Stable surfactant compositions capable of suspending components

FIELD: personal hygiene commodities.

SUBSTANCE: invention relates to aqueous fluid compositions and aims at obtaining fluid non-Newton on shear liquefiable composition suitable for use in personal hygiene commodities, which composition is capable of slurring water-insoluble particles and manifests stability under freezing/thawing conditions. Invention provides fluid composition containing, based on the mass of composition, at least one anionic surfactant, 5-30%, at least one alkanolamine, 0.1-10%, at least one electrolyte, and water. Composition may further contain one or several supplemental surfactants. Composition of invention has layered liquid-crystalline structure, has non-Newton on shear liquefaction property, and ability of slurring water-insoluble particles or partially insoluble components, while being stable in at least one freezing/thawing cycle. Proposed are also a method of preparing indicated composition or stable multiphase composition based thereon.

EFFECT: extended choice of practically useful on shear-liquefiable compositions.

54 cl, 11 tbl, 5 ex

 

Prior inventions

This application in accordance with §119 (e) 35 U.S.C. claims the priority of previously filed and located on the joint review of the USA: No. 60/341845, filed December 21, 2001, and No. 60/369216 filed April 1, 2002, the contents of each of these applications are included in this description by reference.

The technical field

This invention relates to a water free flowing compositions. The invention applies in particular to compositions of surface-active substances, which are free flowing and possess property of non-Newtonian shear thinning and the ability to suspended components.

Prior inventions relating to this area

Documented that free flowing personal hygiene, exhibiting non-Newtonian shear thinning shear and consisting of mixtures of strictly certain surfactants capable of suspending water-insoluble particles or partially insoluble components such as vegetable oil, mineral oil, silicone oil, solid particles, abrasives and similar products. Examples of such tools can be found in U.S. patent No. 5556628 and U.S. patent No. 5965500, each of which is incorporated in this description by reference to the CTE is EIW, they are compatible with this application. These systems provide a means of inclusion in the surfactant mixture of components that would be difficult to include other way, giving you the opportunity to get cosmetic products with multifunctional beneficial effect, including in some cases: cleaning, humidification, improved feeling on the skin, exfoliation/abrasion, new look or a combination of these beneficial actions.

It is assumed that the rheological properties of surfactant solutions, including liquid personal care products depend on their microstructure, i.e. the form and concentration of micelles or other savagegarden structures in solutions.

Micelles do not necessarily have a spherical shape and can be, for example, in the form of a cylindrical micelles or micelles having the form of a disk. At elevated concentrations can form more ordered liquid crystal phase, such as layered phase, hexagonal phase or a cubic phase. Surfactants at a concentration of micelles above the critical, or SMS, can take the form of ordered phases. (SMS is defined as the concentration of surfactant at which it begins to form in the solution micelles.) Rheology phase is PTS is ery important from the point of view of usefulness of the surfactant system.

Rheology of surfactant systems can be described from the point of view of Newtonian and non-Newtonian viscosities. Rheology Newtonian surfactant is described as rheology substances with a viscosity independent of shear rate (i.e. the system will have the same viscosity at the application of various efforts shift). Rheology of non-Newtonian surfactant system is described as the rheology of the system, with the viscosity depending on shear rate. For non-Newtonian razzhizhayuschiesya shear system of surfactants with increasing shear rate the viscosity will decrease. These rheological properties of non-Newtonian surfactant systems provide the possibility of effective suspension of undissolved solids, liquids and gases.

According to U.S. patent No. 5556628, free flowing non-Newtonian, razzhizhayuschiesya shear cosmetics with high stability during storage can be obtained using a set of mixtures of surface-active substances (surfactants), consisting of anionic surfactants, sodium lauryl sulphate (also known as esterified sodium lauryl sulphate) and identified auxiliary surfactants, electrolyte is. The experiments show that non-Newtonian compositions, razzhizhayuschiesya shear can be obtained by following the concepts of U.S. patent No. 5556628. Presented in the patent compositions show high stability of viscosity at room temperature (25° (C) and elevated temperature (45°). However, such systems may not be optimal performance under all conditions, including, but without limitation specified conditions of freezing/thawing.

For stabilization of systems with layered phases in other publications suggesting the use of fatty acid structure-formers (see, for example, U.S. patent No. 6150312, 5952286 and 5962395). The disadvantage inherent in such systems that require fatty acid ingredients, is that the fatty acids in hard water to form insoluble salts (salts of CA2+and Mg2+)that leave undesirable residue on surfaces such as hair, skin, solid surface, etc. Specified precipitate particularly undesirable in the formulation of shampoo, as it will cause fading of the hair and will act as a foam suppressor that negatively affects vysokopoyasny cosmetic compositions, such as shampoos and compositions for body wash.

In addition, it is difficult to maintain the stability and integrity of other known who the shaft systems, especially in conditions of freezing/thawing.

Accordingly, it is desirable to obtain a free flowing non-Newtonian razzhizhayuschiesya when shifting composition suitable for use in personal care products, has the ability to suspend the water-insoluble particles and stable under conditions of freeze/thaw.

The invention

Can be obtained a stable free flowing cosmetic compositions containing anionic surfactants, electrolytes and alkanolamide, which include long chain aliphatic hydroxy- (or polyhydroxy)amide (hereinafter referred to in the description alkanolamide long chain aliphatic acids or alkoxysilane long chain aliphatic hydroxy- (or polyhydroxy)amide (hereinafter referred to in the description alkoxycarbonyl alkanolamide long chain aliphatic acids), which are ideal for suspension of insoluble particles.

Compositions of the invention can be obtained by any method suitable for the formation of a free flowing composition. To create balance, which gives a free flowing composition, the amount of electrolyte, surfactant and alkanolamide can be adjusted in various ways.

The composition of the invention is t to be used for suspension components, used for skin care and hair care, including, but without limitation, absorbers of ultraviolet rays, components that have a conditioning effect on the hair, components that have a conditioning effect on the hair and skin for use in the media "2 in 1" for child care, components that have a conditioning effect on the skin, antimicrobial components, the polymers used in the means for stylized hair styling and care of the skin (including, for example, means for rinsing, such as shampoos), polymers with a conditioning effect to hair care means and skin precipitable polymers with conditioning effect for accelerated push for hair and skin, polymers with conditioning effect of high molecular masses and/or high density of cationic charge, designed to care for hair and skin, surfactants, usually associated with solid compositions (such as cocoylisethionate), and nabukenya polymers, which hydratious only when applying. Compositions of the invention can also be used to obtain a stable multi-phase personal care products, including tools with painted stripes designs available on compositions for body wash,shampoo for hair natural cleansers for the skin, care of children, the formulations facial wash and means for skin care.

Detailed description of the invention

The invention relates to surface-active compositions, which appears non-Newtonian shear thinning shear (hereinafter they are referred to as free flowing compositions). These compositions contain water, at least one anionic surfactant, at least one electrolyte and at least one alkanolamide. The composition can additionally contain water-insoluble particles or partially insoluble components, and/or one or more additional surfactants selected from the group consisting of anionic surfactants, nonionic surfactants, amphoteric and/or zwitterionic surfactants and cationogenic surfactants. Compositions of the present invention are stable compositions that can be suspended trudnovymyvaemye components, and are stable under the conditions of freezing/thawing.

Without intending to be bound by theory, the authors believe that in some examples, the compositions of the invention may have a layered structure. Compositions of the invention are freedoms is otakuzine and possess property of non-Newtonian shear thinning and the ability of the suspended components (these properties are known for the surface-active compositions with layered phases).

Anionic substance may represent, for example, an aliphatic sulfonate, such as a primary alkane (e.g., With8-C22) sulfonate, primary alkane (e.g.8-C22) disulfonate,8-C22alkanesulfonyl,8-C22hydroxyethanesulfonic or allylglycidylether (AGS); aromatic sulfonate such as Las, or their mixture.

Anionic surfactant can also be alkylsulfates (for example, C12-C18-alkylsulfates) or esterified by alkylsulfates (including the esterified alkylglycerols). Preferred esterified with an alkyl sulphates are compounds having the formula:

where R is alkyl or alkenyl containing from 8 to 18 carbon atoms, usually from 12 to 18 carbon atoms; n has an average value of usually from 0 to 7; preferably from 0.5 to 3; and M means solubilizers cations such as the cations of sodium, magnesium, potassium, ammonium or substituted ammonium. In some embodiments, as a group R preferred Laurila and redecilla group. The hydrophobic chain may be saturated or unsaturated, having a straight chain or branched.

Anionic surfactant may also predstavljaetsja alkylsulfonate (including mono - and dialkyl, for example, With6-C22-sulfosuccinate), alkyl - and allcounty, alkyl and acylcarnitine, sulfoacetate,8-C22-alkylphosphate, complex alkalemia esters of phosphoric acid, complex alkoxyalkyl esters of phosphoric acid, azelastine,8-C22-monoalkylamines and maleate and utilizationin.

Sulfosuccinate may include monoalkylbenzenes having the formula:

amido-MEA (monoethanolamide)sulfosuccinate formula:

where R4is in the range from C8to C22the alkyl and M means solubilizers cation; and amido-MIPA. (monoisopropanolamine) sulfosuccinate formula:

where M is defined as above for formula (ii), and R is in the range from C8to C22the alkyl.

As anionic surfactants are also included alkoxysilane tetracarboxylate and alkoxysilane sulfosuccinate corresponding to the formula:

where M is defined as above for formula (ii), and R is in the range from C10to C22the alkyl.

Sarcosinate is usually provided by the formula:

RCON(CH3)CH2CO2M, where R is in the range from C8to C22is Lila and M means solubilizers cation.

Taurate are usually identified by the formula:

where R2is in the range from C8to C22of alkyl, R3is in the range from C1to C4the alkyl and M means solubilizers cation.

Another class of anionic surfactants represented by the carboxylates of the following formula:

where R is C8-C22alkyl; n is from 0 to 20; and M is defined as above in formula (ii). Other carboxylates, which can be used include aminoalkylphosphonic.

Other anionic surfactants that can be used to represent a8-C22utilizationin. These esters are obtained by reaction of isetionate alkali metal with a mixture of aliphatic fatty acids having from about 6 to about 22 carbon atoms and the value iodine value of less than about 20. At least about 75% of the fatty acids in the mixture are from about 12 to about 18 carbon atoms and up to about 25% of the fatty acids have from about 6 to about 10 carbon atoms.

Utilization can represent such alkoxycarbonyl isetionate, which is described in U.S. patent No. 5393466 Ilardi et al., included in this description by reference to the extent to which he is the tsya compatible with this invention and application. The compound has the General formula:

where R is alkyl group having from 8 to 22 carbon atoms, m denotes an integer from 1 to 4, X and Y denote hydrogen or an alkyl group having from 1 to 4 carbon atoms and M+means monovalent cations such as the cations of sodium, potassium or ammonium.

In some embodiments, the preferred anionic surfactants with branched alkyl chains, such as tradecraft sodium. In some embodiments, may also be used mixtures of anionic surface-active substances.

The amount of anionic surface-active ingredient usually makes up from about 5 wt.% to about 30 wt.% and preferably from about 10 wt.% to about 20 wt.% relative to the weight of the composition.

All numbers in this description indicating amounts or ratios of materials or conditions of reaction, physical properties of materials and/or application, should be understood as a variable by using the word "about", except in the examples, or where explicitly stated otherwise.

If this description uses the expression "weight of surface-active substances", "weight" should be understood in the average weight of active surfactant except in tables.

The electrolyte which may be added to the composition separately, or it can be included as part of one of the other starting materials. The electrolyte preferably contains an anion, including phosphate, chloride, sulfate or citrate, and cations, including sodium, ammonium, potassium, magnesium or mixtures thereof. Some preferred electrolytes are sodium chloride or ammonium sulfate and sodium or ammonium.

The electrolyte should be present in such quantity that contributes to the formation of free flowing composition. The specified amount will typically be from about 0.1 wt.% to about 15 wt.%, preferably from about 1 wt.% to about 6 wt.%, but if necessary it can be changed.

Typically, the composition comprises from about 3 wt.% to about 30 wt.% surface-active substances. Often surfactants are sold in the form of solutions in water or other solvents which dilute them to the content of the surfactant is less than 100%, therefore, the terms "surfactant" means the actual quantity of surface-active substances, caught in a free flowing composition of a commercial surface-active drug.

In some embodiments, it is desirable that at least one of the components of the compositions, such as anionic surfactant, had the aliphatic chain, which has the branching or unsaturation or a combination of both. "Branching" or "branched" means that at least one carbon atom aliphatic chain is connected to three or four other carbon atoms. "Unsaturation" means that at least two carbon atoms of aliphatic chains are connected by a double bond.

The composition also includes at least one alkanolamide having the General structural formula:

where R represents a C8-C24,or in some embodiments, preferably8-C22or in other variants With8-C18aliphatic group with a saturated or unsaturated, straight or branched chain, R1and R2are the same or different With2-C4aliphatic groups, straight or branched chain, x is from 0 to 10, y is from 1 to 10, with the sum of x and y is less than 10 or equal to 10.

In other words, alkanolamide preferably has a8-C24aliphatic chain and alkanolamide may include from one to two alkanols groups, which can have either a hydrocarbon main chain, or CNS main chain. Hydrocarbon alcoholnye group can be a2-C4aliphatic group with a straight or branched chain. The number alkanolamide in the composition is from about 0.1 wt.% to the Colo 10 wt.% and in some embodiments preferably from about 2 wt.% up to about 5 wt.%. Some preferred alkanolamine include cocamide MEA (communautarisme) and cocamide MIPA. communityrelated).

The term "alkanolamine" is used hereinafter in the description to enable aggregate of alkanolamides long chain aliphatic acid, alkoxysilane of alkanolamides long chain aliphatic acid, and mixtures thereof. In addition, alkanolamide long chain aliphatic acids may be referred to in the art alkanolamide fatty acids. The term "alkoxycarbonyl" means alkanolamide produced from (R1O)xH, where R1represents a C2-C4aliphatic group with a straight or branched chain and x is equal to from 2 to 10. Examples of formulations of free flowing compositions shown below in table 1. One advantage of this invention over previously known compositions is that for formulations of the compositions of the invention are not required as a regulator of fatty acid structure-former, which, in turn, can negatively affect performance products.

For the formation of a free flowing composition capable of suspending water-insoluble particles or partially insoluble components may be included optional additional surfactants of the classes neino the military surfactants, amphoteric and/or zwitterionic surface-active substances.

Amphoteric and/or zwitterionic surfactants that can be used in this invention preferably include at least one acid group, which may be a carboxylic group or sulfonic acid. Such surfactants include Quaternary nitrogen and therefore represent a Quaternary amicability. They usually include alkyl or alkenylphenol group containing from 7 to 18 carbon atoms, and usually obey the General structural formula:

where R1means alkyl or alkenyl containing from 7 to 18 carbon atoms; each of R2and R3independently represents hydrogen, alkyl, hydroxyalkyl or carboxylic containing from 1 to 3 carbon atoms; n is from 2 to 4; m is from 0 to 1; X means alkylene containing from 1 to 3 carbon atoms, optionally substituted with hydroxyl; and Y represents-CO2- or-SO3-.

Suitable amphoteric and/or zwitterionic surfactants, obeying the above General formula include simple betaines of formula:

and aminobutane formula:

where m is 2 or 3.

In both formulas (xi) and (xii) R 1, R2and R3determined, as indicated in the formula (x). R1may, in particular, to be a mixture of C12and C14-alkyl groups, produced from coconut oil, so that at least half, preferably at least three quarters of the groups R1had from 10 to 14 carbon atoms. R2and R3preferably represent methyl.

An additional possibility is that the amphoteric and/or zwitterionic detergent was sulfobetaine formula:

where m is 2 or 3, or variants, in which -(CH2)3SO3replaced by a group

In these formulas (xiii), (xiv) and (xv) R1, R2and R3determined, as indicated in the formula (x).

Can also be used atacamite and diaphaneity. Emphaticaly typically correspond to the following formula:

and diaphaneity typically correspond to the following formula:

where R is an aliphatic group containing from 8 to 18 carbon atoms, and M stands for a cation, such as a cation of sodium, potassium, ammonium or substituted ammonium. In some embodiments, the preferred lauroamphoacetate sodium, cocoamphoacetate sodium, dinate is lauroamphoacetate and dinitrilotetraacetic.

Surfactant system or composition may also optionally include a non-ionic surfactant. Nonionic surfactants that may be used include in particular the reaction products of compounds having a hydrophobic group and a reactive hydrogen atom, for example aliphatic alcohols, acids, amides or alkyl phenols with acceleratedly, in particular with ethylene oxide, taken or separately, or in combination with propylene oxide. Specific nonionic surfactants include condensates of alkyl (C6-C22) phenols and ethylene oxide, the condensation products of aliphatic (C8-C18) primary or secondary linear or branched alcohols with ethylene oxide, and products obtained by condensation of ethylene oxide with the reaction products of propylene oxide and Ethylenediamine. Other so-called nonionic surface-active compounds include alkylamines, alkylamidoamines, alkyl(tertiary phosphine)oxide, diallylsulfide, esters With8-C22alcohols or ethoxylated alcohols with aliphatic fatty acids, alkoxylalkyl, sorbitan, esters sorbitan and esters of sucrose.

Nonionic surfactant may also be saharaui the Ohm, such as polycaproamide. More specifically surfactant may be one of lactobionate described in U.S. patent No. 5389279, or one of sheremetov described in U.S. patent No. 5009814, both of these patents are included in this description by reference to the extent that they are compatible with this application.

Other surfactants that may be used are the substances, which are described in U.S. patent No. 3723325, and alkylpolyglycoside nonionic surfactants disclosed in U.S. patent No. 4565647, both of these patents are included in this description by reference. Preferred alkylpolyglucoside are alkylpolyglycoside formula

where R2selected from the group consisting of alkyl, alkylphenyl, hydroxyalkyl, hydroxyalkyloxy and mixtures thereof, where the alkyl groups contain from about 10 to about 18, preferably from about 12 to about 14 carbon atoms; n is from 0 to about 3, preferably 2; t is from 0 to about 10, preferably 0; and x is from about 1.3 to about 10, preferably from about 1.3 to about 2.7. Glycosyl preferably produced from glucose. To obtain these compounds are first formed alcohol or alkylphenolethoxylates the th alcohol, and then one of these compounds is subjected to interaction with glucose or a source of glucose with the formation of glucoside (accession in position 1). Additional glucosamine links can be attached between position 1 and position 2, 3, 4 and/or 6, preferably the position of the 2 preceding helicoiling links.

In some embodiments, preferred nonionic surfactants include modified alkoxysilane fatty acids alcohols or alkylpolyglycoside. Preferred in some embodiments, amphoteric and/or zwitterionic surfactants include betaines, Sultani, atacamite, diaphaneity or mixtures thereof. The total number of active non-ionic surfactants and amphoteric and/or zwitterionic surfactants is generally from about 1 wt.% to about 20 wt.% and preferably from about 3 wt.% up to about 10 wt.%.

The total amount of all surfactants, for example anionic surfactants, nonionic surfactants, amphoteric and/or zwitterionic surfactants and cationogenic surfactants, taken together, is usually from about 8 wt.% to about 30 wt.% and preferably from about 10 wt.% up to about 25 wt.%. Some of the options that preferably to at least one of the surfactants had an aliphatic chain, which has a branching or desaturation or a combination of both.

One variant of the invention relates to water-free flowing composition comprising (a) water, (b) at least one anionic surfactant comprising a hydrophobic substance containing a linear or branched hydrophobic group, (C) at least one electrolyte (which may be added or separately or included in one of the source materials), and (d) at least one alkanolamide. The mixture may additionally contain water-insoluble particles or partially insoluble components and/or one or more additional surfactants selected from the classes of anionic, nonionic, amphoteric, zwitterionic and cationogenic or from their combination.

Surface-active substances (as defined in this description as surface-active agents, including any of anionic, nonionic, amphoteric and/or zwitterionic and cationogenic surface-active species and their various mixtures) are included in the composition in such amounts that the composition has been observed: (i) non-Newtonian shear thinning shear, (ii) a viscosity equal to or greater about 3000 SP, measured by the viscometer is of rockfeld LVT rotating with the 6th speed terminal 3 at 25° C for 30 seconds, and (iii) the viscosity is stable under conditions of freeze/thaw without having to add a separate stabilizer freeze/thaw. The term "sustainable" is defined in this description as % reduction of viscosity of not more than 40%, preferably not more than 35%, measured at least after one (1) cycle of freezing/thawing, preferably, at least after four (4) cycles of freezing/thawing. As used in this description, the expression "one cycle of freeze/thaw" means a 24-hour period when the temperature of the environment immediately surrounding the test sample, is equal to -10°C for 12 hours and 25°C for 12 hours. In some embodiments, the composition may hold the water-insoluble particles or partially insoluble components in suspension.

The compositions of this invention are intended to include all formulations comprising presented in this description of the surfactant system, alkanolamide, electrolyte and water. These songs are free flowing and capable of suspending the component(s)that provide(s) a beneficial effect, and to maintain stability in conditions of freezing/thawing.

In some embodiments of the present invention, it is desirable to include in the loose the fluid composition of the water-insoluble particles or partially insoluble components. The terms "water-insoluble particles and partially insoluble components" means solid or non-solid substance, which is not fully solubilized in the aquatic environment of the claimed compositions and include either insoluble or partially soluble particles. The terms "water-insoluble particles and partially insoluble components" is also understood as meaning, covering such cases, when a solid or non-solid substances are present at concentrations above their solubility limit, and so part of them is not dissolved. Typically the water-insoluble particles or partially insoluble components can be represented as solid particles, liquid ingredients, gases, or mixtures thereof. Some preferred examples of gases include air bubbles. The solid particles may include, for example, solid particles of zinc-pyrithione, mica, aluminum oxide, silicon pigments, moisturizing beads, natural abrasives, synthetic abrasive materials (to exfoliate), such as polyoxyethylene balls, and apricot seeds. The water-insoluble particles usually have an average particle size of from about 0.5 to about 3000 microns in diameter. The ability to suspend the water-insoluble particles or partially soluble components is desirable hallmark the second feature free flowing non-Newtonian razzhizhayuschiesya shear liquid composition of the present invention.

Other examples of components that can be suspended by the compositions of the present invention, represent a number of components that have beneficial effects. The terms "component, providing a beneficial effect"means any active ingredient which must be transported to the skin or hair, or skin or hair or both in/on the skin and hair. Suspended agents that have beneficial effects may be present in amount from about 0 to about 35 wt.% relative to the weight of the composition.

More specifically, the suspended agents that have beneficial effects may include: vegetable oils, including peanut oil, castor oil, cocoa butter, coconut oil, corn oil, cottonseed oil, olive oil, palm kernel oil, rapeseed oil, safflower oil, sesame oil and soybean oil; esters, including Boutilimit, cetylpalmitate, decillia, literallayout, glyceryltrinitrate, literallayout, glycerylmonostearate, exellent, isobutylacetate, isolatedstore, isopropyltoluene, isopropylene, isopropylidene, isopropylmyristate, isopropyl, isopropylene, monolaurate propylene glycol, ricinoleic propylene glycol, propylene glycol stearate, and propylene glycol isostearate; animal fat is, including acetylated lanolin alcohols, lanolin, lard, mink fat and tall oil; and fatty acids and alcohols, including beenbuy acid, palmitic acid, stearic acid, beganovic alcohol, cetyl alcohol, Aksaray alcohol and societally alcohol.

Other examples of suitable components that have beneficial effects include: components for depigmentation; reflectors; absorbers of ultraviolet rays, thickening components; components for moisture and easy combing hair; film forming polymers; water-retaining substance; amino acids and their derivatives; antimicrobial components; protivougrevoe means; a means of slowing the aging process; antiseptics; analgesics; local anesthetics; anti-hair loss; inhibitors of hair growth; anti-inflammatory agents; proteins (proteins); deodorants and antiperspirants; means for treatment of dandruff, seborrheic dermatitis and psoriasis; emollient cosmetic substances for skin and skin moisturizers; hair conditioners; hair softeners; hair moisturizers; vitamins; components contributing to tan; components, whitening the skin; antifungal agents, such as anti-fungal components of care for the feet; depilatories; components against skin irritation; means the and, applied with hemorrhoids; insecticides; pigments or cloud emulsions; moisturizing beads; natural abrasives; synthetic abrasive materials such as polyoxyethylene balls, mineral oil, petrolatum, silicone oils, polyalkyloxy, polyalkylacrylate, sunscreen and the like; and mixtures thereof.

Examples of suitable reflectors include mica, aluminum oxide, calcium silicate, glikolevaya, picoliter, silicon dioxide, magnetoresistant sodium and mixtures thereof.

Examples of suitable absorbers of ultraviolet rays include benzophenone, Bordelon, RAVA (para-aminobenzoic acid), Batyrova, cinemediapromo, dinitrodiethylenediamine, methoxycinnamate potassium and mixtures thereof.

For use in this invention are suitable commercially available thickening components capable of imparting the appropriate viscosity of the composition. Examples of suitable thickening components include complex mono - or diesters of polyethylene glycol (PEG) formula:

where z denotes an integer from about 3 to about 200; fatty acids containing from about 16 to about 22 carbon atoms; esters of fatty acids and alkoxyphenyl; alkoxybenzenes complex mono - and diesters of fatty acids and glaze the ina; hydroxyethylcellulose; alkylaryl; hydroxyethylcellulose and mixtures thereof. More specifically, suitable thickening components include, but are not limited to, for example, beenaccumulated, cetyl alcohol, quaterni 46, propylene glycol (PG)-hydroxyethyl cellulose, cocodimonium, polyquaternium 6, polyquaternium 7, quaterni 18, a mixture of oleate/Cocoate PEG-18-glycerol, a mixture of a copolymer of acrylates and spirit-50-acrylates, Laureth 3, and propylene glycol, a mixture of aminopropylation fatty acids of coconut oil and literallayout, a mixture of propylene glycol, PEG-55 and propilengikolya and mixtures thereof. Preferred thickeners include ester of polyethylene glycol and more preferably distearate PEG-150.

Suitable components for moisture and easy combing hair include dioleoylphosphatidylcholine, di(maiolati) hydroxyethylaminomethyl, hydroxyethylidenediphosphonic, leukonychia, polyquaternium 47, stearalkonium, treatymonitoring, qualitativeprinciples, hydroxypropylmethylcellulose and mixtures thereof.

Suitable film-forming polymers include polymers which dries to give on the hair, skin or nails essentially continuous coating or film. Examples of suitable film-forming p the materials include a copolymer of acrylamidophenylboronic and of acrylamide; the copolymer corn starch, acrylamide and sodium acrylate; polyquaternium 10, polyquaternium 47; a copolymer of methylparabene and maleic anhydride; copolymers of styrene and acrylates; and mixtures thereof.

Suitable for use in the present invention are commercially available water-holding substances that are able to provide compositions moisturizing ability and conditioning properties. Water-retaining substance is preferably present in amount from about 0% to about 10%, more preferably from about 0.5% to about 5% and most preferably from about 0.5% to about 3%, based on the total weight of the composition. Examples of suitable water-retaining substances include water-soluble liquid polyols, such as glycerin, propylene glycol, hexyleneglycol, butyleneglycol, pentilenglikol, dipropyleneglycol and mixtures thereof; polyalkylene glycols of the formula:

where R" means alkylenes group containing from about 2 to about 4 carbon atoms, and b denotes an integer from about 1 to about 10 (e.g., PEG-4); simple polietilenglikolya esters of methylglucose having the formula:

where C denotes an integer from about 5 to about 25; urea, fructose; glucose; honey; lactic acid; maltose; sodium glucuronate; and mixtures thereof. More PR is doctitle embodiment, the hydrophilic substance is a glycerin.

Suitable amino acids which can be beneficial for hair and skin and in some cases can be included in the composition of the present invention as a component with a conditioning effect, include amino acids resulting from the hydrolysis of various proteins, as well as their salts, esters and acyl derivatives. Examples of such amino acids include, but are not limited to, amphoteric and/or zwitterionic amino acids, such as alkylmethacrylamide; sterilazation, capillarisation silk, capillarisation collagen; capillarisation keratin; capillarisation peanuts; cocodimethylamine silk; amino acids gluten free corn; cysteine; amino acids of the hair keratin; amino acids hair, such as aspartic acid, threonine, serine, glutamic acid, Proline, glycine, alanine, polycystin, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, cysteine acid, lysine, histidine, arginine, cysteine, tryptophan, citrulline; other amino acids silk and wheat amino acids; and mixtures thereof.

Suitable proteins that can be beneficial for hair and skin and in some cases can be included as components of the conditioning effect, include such polymers, which have long chain that is at least about 10 carbon atoms, and a high molecular weight that is at least about 1000, and is formed by samakonasana amino acids. Examples of such proteins include collagen, desoksiribonukleaza, audirovannyj protein from corn cobs, keratin, milk protein, protease, whey protein, silk protein, sweet almond, protein, wheat germ, wheat protein, alpha helical and beispiele of keratin proteins, the proteins of hair, such as proteins of intermediate filaments, high-sulphur proteins, sverhvysokoskorostnaya proteins, proteins that associate with intermediate filaments, proteins with a high content of tyrosine, protein tyrosine with a high content of glycine, trichohyalin and mixtures thereof.

Examples of suitable vitamins, which can be beneficial for hair and skin and in some cases can be included as components of the conditioning effect, include vitamin b complex, including thiamine, nicotinic acid, Biotin, Pantothenic acid, choline, Riboflavin, vitamin B6, vitamin B12, pyridoxine, Inositol, carnitine, vitamins A, C, D, E, K and their derivatives, such as vitamin a palmitate; and provitamins, such as panthenol (provitamin B5), panthenol triacetate, and mixtures thereof.

Examples of bactericidal components for skin care include bacitracin, erythromycin, triclosan, neomycin, t is tricyclin, chlortetracycline, benzenehexachloride, phenol, parachlorometaxylenol (PCMX), trichlorsilane (TCC), chlorhexidine (CHG), zinc-pyrithione, selenium sulfide, and mixtures thereof.

Examples of suitable emollients cosmetic substances for skin and skin moisturizers include vegetable oils such as peanut oil, castor oil, cocoa butter, coconut oil, corn oil, cottonseed oil, olive oil, palm kernel oil, rapeseed oil, safflower oil, sesame oil and soybean oil; esters, such as Boutilimit, cetylpalmitate, decillia, literallayout, glyceryltrinitrate, literallayout, glycerylmonostearate, exellent, isobutylacetate, isolatedstore, isopropyltoluene, isopropylene, isopropylidene, isopropylmyristate, isopropyl, isopropylene, monolaurate propylene glycol, ricinoleic propylene glycol, propylene glycol stearate, and propylene glycol isostearate; animal fats, such as acetylated lanolin alcohols, lanolin, lard, mink fat and tall oil; fatty acids and alcohols beganovi acid, palmitic acid, stearic acid, beganovic alcohol, cetyl alcohol, Aksaray alcohol and societally alcohol.

Additional components for skin care and components with a conditioning effect on the skin include salicylic is islote, alpha-hydroxy acids, vitamins, vitamins, abrasives, silicones, silicone derivatives, polymers, natural oils, synthetic oils, mineral oils, lanolin, vegetable oils, zosterisessor, literallayout, metalglory 10, metalglory 20, chitosan and mixtures thereof.

Examples of suitable hair conditioners include silicones, derivatives, silicones, natural oils, synthetic oils, nonionic poverhnosti-active substances, cationogenic surfactants, waxes and polymers. Can also be used quaternion compounds such as behenamidopropyl PG-demoniacal, triethylammonium, aminoethylaminomethyl digidrirovannoe tall oil, and mixtures thereof, as well as lipophilic compounds such as cetyl alcohol, stearyl alcohol, gidrirovannogo polydecene, and mixtures thereof.

Examples of suitable polymers used in hair conditioners include natural and/or synthetic cationogenic polymers, for example quaternionic guar, quaternion cellulose, polyquarternium-7, and such polymers typically at concentrations of from about 0.1 wt.% up to about 3 wt.% relative to the weight of the specified composition; natural and/or synthetic nonionic polymers, such as alkoxycarbonyl or propoxide is consistent guar or cellulose, alkyllead or cellulose, polyethylene glycol, or a mixture of natural and synthetic nonionic polymers typically at concentrations of from about 0.1 wt.% to about 3.0 wt.% relative to the weight of the specified composition; and polyhedrally humectants, for example glycerol, propylene glycol, sorbitol and the like polymers. The preferred concentration polyhedrally moisturizing components are usually in the range from about 0.2 wt.% up to about 0.5 wt.% relative to the weight of the composition.

Examples of suitable emollients include hair such silicone compounds that are either non-volatile or volatile, or a mixture of such compounds, which are soluble or not soluble in water, or mixtures thereof. Examples of suitable silicones include organosiloxane polysiloxane, which are either linear or cyclic polymers of monomers silicone/oxygen and which include acidisation, a copolymer of cetyltrimethylammoniumbromide and polioptila, cyclomethicone, a copolymer of Dimethicone and polyol copolymer dimetikona and polylactate, copolymer of hydrolyzed soy protein and dimethylamylamine, siliconware 13, a copolymer of stearalkonium and polioptila, stearamidopropyl and mixtures thereof.

Examples of suitable humectants include hair simple pan is unilateraly ether, phytantriol and mixtures thereof.

Examples of sunscreens include butylperoxybenzoate, octylmethoxycinnamate, oxybenzone, octocrylene, octisalate, vinylbenzenesulfonic acid, ethylhydroxylamine, methylanthranilate, aminobenzoic acid, cinoxate, diethanolammonium, glycerylmonostearate, titanium dioxide, zinc oxide, oxybenzone, octyldodecyl p-aminobenzoic acid RAVA (padimate About), red petrolatum, and mixtures thereof.

An example of a suitable component contributing to tan, includes dihydroxyacetone.

Examples of components, whitening the skin, include hydroquinone, catechin and its derivatives, ascorbic acid and its derivatives and mixtures thereof.

Examples of suitable insecticides, including repellents to deter insects, protivochesotocnaya means and means to control head lice are permethrin; pyrethrin; piperonylbutoxide; Imidacloprid; N,N-diethyltoluamide, which represents a compound containing predominantly the meta isomer, i.e., N,N-diethyl-m-toluamide, also known as DEET; compounds of the formula:

where R5represents a branched or unbranched alkyl group containing from about 1 to about 6 carbon atoms, R6represents H, methyl or ethyl, R7represents the t a branched or unbranched alkyl or CNS group, containing from about 1 to about 8 carbon atoms and is a group -- CN or -- COOR8where R8represents a branched or unbranched alkyl group containing from about 1 to about 6 carbon atoms; natural or synthetic pyrethroids, with natural pyrethroids are contained in pyrethrum; extract of ground flowers Chrysanthemum cinerariaefolium or Chrysanthenum coccineum; and mixtures thereof. The structure of the formula (xx) is a compound ethyl 3-(N-butylacetamide)propionate, where R7represents a group-CH3, R5is a n-boutelou group, R6is H, K is COOR8and R8means ethyl.

Example antifungal component means of foot care includes tolnaftate.

Examples of suitable means for hair removal include thioglycolate calcium, thioglycolate magnesium, thioglycolate potassium, thioglycolate strontium and mixtures thereof.

Examples of suitable analgesics for topical application and local anesthetics include benzocaine, dibucaine, benzyl alcohol, camphor, capsaicin, capsicum, a mixture of natural resins with capsicum, prigoreloe oil kalokerinou juniper, menthol, methylnicotinate, methyl salicylate, phenol, resorcinol, turpentine, and mixtures thereof.

Examples of suitable antiperspirants and deodorants include chlorhydrate aluminum, chlorhidrate aluminum-zirconium and the x of the mixture.

Examples of suitable components against skin irritation include camphor, menthol, methyl salicylate, peppermint oil, clove oil, ichthammol and mixtures thereof.

An example of a suitable anti-inflammatory agent is hydrocortisone.

Examples of suitable agents which are used for hemorrhoids include anesthetics such as benzocaine, hydrochloride pramoxine, and mixtures thereof; antiseptics, such as benzathine; binding agents, such as zinc oxide, subgallate bismuth, balsam Peru, and mixtures thereof; means for protection of the skin, such as cod liver oil, vegetable oil, and mixtures thereof.

Examples of suitable means, have beneficial effects on the skin with therapeutic components, which are effective for the treatment of dandruff, seborrheic dermatitis and psoriasis, as well as associated symptoms include zinc pyrithione; shale tar and its derivatives, such as sulfonated shale tar; selenium sulfide; sulfur; salicylic acid, coal tar; povidone-iodine; imidazoles such as ketoconazole, dichlorophenylisocyanate, clotrimazole, Itraconazole, miconazole, climbazole, tioconazole, sulconazole, butoconazole, fluconazole; miconazoleinchite and any possible stereoisomers and derivatives, such as anthralin; pyroceramic (Octopirox); selenium sulfide; ciclopirox is in; protivopsoriaticescoe tools, such as vitamin D analogues such as calcipotriol, calcitriol and caculator; vitamin a analogues, such as esters of vitamin a, including palmitate vitamin a, retinoids, retinol and retinoic acid; corticosteroids, such as hydrocortisone, clobetasone, butyrate, globalatlanta and mixtures thereof.

Some preferred components that have beneficial effects in the treatment of dandruff, seborrheic dermatitis and psoriasis, as well as associated symptoms include sulfonated shale oil, Albiol, 6-(1-piperidinyl)-2-4-pyrimidinediamine-3-oxide, finasteride, ketoconazole, salicylic acid, zinc pyrithione, coal tar, benzoyl peroxide, selenium sulfide, hydrocortisone, sulfur, menthol, precommercial, chloride of trichotillomania, polyquaternium 10, panthenol, antinatriuretic, vitamin a and its derivatives, vitamin C and its derivatives vitamin C and its derivatives vitamin D and its derivatives vitamin E and its derivatives, vitamin K and its derivatives, keratin, lysine, arginine, hydrolyzed wheat, hydrolyzed silk, octylmethoxycinnamate, oxybenzone, Minoxidil, titanium dioxide, dioxide, zinc, retinol, erythromycin, tretinoin and mixtures thereof.

Examples of components that have beneficial effects and is suitable for cured the I hair loss, include, but are not limited to, the discoverers of potassium channels or vasodilators peripheral blood vessels, such as Minoxidil, diazoxide, and such compounds as N-cyano-N-(tert-pentyl)-N'-3-pyridinylamino("P-1075), which are disclosed in U.S. patent No. 5244664 included in this description by reference; vitamins, such as vitamin E and vitamin C, and derivatives thereof, such as acetate vitamin E and palmitate vitamin C; hormones such as erythropoietin; prostaglandins, such as prostaglandin EI and prostaglandin F2-alpha; fatty acids such as oleic acid; diuretics, such as spironolactone; proteins against thermal shock ("HSP"), such as HSP27 and HSP72; calcium channel blockers such as verapamil HCl, nifedipine and diltiazemcream; immunosuppressive drugs such as cyclosporin and Fk-506; inhibitors of 5-alpha-reductase such as finasteride; growth hormones such as EGF, IGF and FGF; TGF-beta growth factor; tumor necrosis factor; non-steroidal anti-inflammatory tools such as benoxaprofen; retinoids and their derivatives, such as tretinoin; cytokines, such as IL-6, IL-1 alpha and IL-1 beta; adhesion molecules cells, such as ICAM; glucocorticoids such as betamethasone; plant extracts, such as extracts of aloe Vera, clove, ginseng, rehmannia, Swertia albmarginata, orange sweet, Zanthoxylum, Serenoa repens (Palma, Serenoa), Hypoxis rooperi, nettle, pumpkin seed Pepo and pollen of rye seed; other plant extracts, including extracts of sandalwood, roots beetroot red, chrysanthemum, rosemary, burdock, and other activators, accelerating hair growth is disclosed in DE4330597 included in this description by reference to the extent compatible with this application; homeopathic agents such as Kalium Phosphoricum D2, Azadirachta indica D2, and Joborandi D1; genes for cytokines, growth factors and anti-balding men floor; antifungal components, such as ketoconazole and eluvial; antibiotics such as streptomycin; inhibitors of proteins, such as cycloheximide; acetazolamide; benoxaprofen; cortisone; diltiazem; hexachlorobenzene; as; nifedipine; penicillamine; phenothiazines; pinacidil; psoralens; verapamil; zidovudine; alpha glycosidically rutin, having at least one rutin selected from quercetin, isoquercitrin, hesperidin, naringin and metilgistamina; and flavonoids and their transglucosidase derivatives, all of which are disclosed in JP7002677 included in this description by reference to the extent compatible with this application; and mixtures thereof.

Examples of components that have beneficial effects and is suitable for use in podavini the hair growth, include semipretioase, such as trypsin; vitamins such as alpha-tocopherol (vitamin E) and derivatives thereof, such as tocopherol acetate and tocopherolacetate; antineoplastic agents such as doxorubicin, cyclophosphamide, chlormethine, methotrexate, fluorouracil, vincristine, daunorubicin, bleomycin and hydroxycarbamide; anticoagulants, such as heparin, heparinoid, coumarins, detran and indandione; remedies against diseases of the thyroid gland, such as iodine, thiouracil and carbimazole; lithium and lithium carbonate; interferons such as alpha interferon, alpha-2A-interferon and alpha 2b-interferon; retinoids, such as retinol (vitamin a), isotretinoin; glucocorticoids such as betamethasone and dexamethasone; protivoepidemicheskie tools such as triparanol and clofibrate; thallium; mercury; albendazole; allopurinol; amiodarone; amphetamines; androgens; bromkriptin; butyrophenones, carbamazepine; cholestyramine; cimetidine; clofibrate; danazol; desipramine; dickersin; ethambutol; ethionamide; fluoxetine: gentamicin; gold salts; hydantoins; ibuprofen; imipramine; immunoglobulins; indandione; indomethacin; Itraconazole; levodopa; maprotiline; methysergide; metoprolol; metyrapone; nadolol; nicotinic acid; potassium thiocyanate; propranolol; pyridostigmine; salicylates; sulfasalazin; terfenadine; thiamphenicol; thiouracil; trimetal is he; triparanol; valproate acid; and mixtures thereof.

Examples of suitable AIDS in slowing the aging process include inorganic sunscreens such as titanium dioxide and zinc oxide; organic sunscreens such as octylmethoxycinnamate and derivatives thereof; retinoids; vitamins, such as vitamin E, vitamin a, vitamin C, vitamin b and derivatives thereof, such as acetate vitamin E palmitate vitamin C and similar funds; antioxidants including beta-carotene, alpha-hydroxy acid such as glycolic acid, citric acid, lactic acid, malic acid, mandelic acid, ascorbic acid, alpha-hydroxybutyric acid alpha-occaisonally acid, alpha-occaisionaly acid, atractiva acid, alpha-oksietilenovym acid, etherpiraat, galacturonic acid, glucoheptonate acid, glucoheptonate,4-lactone, gluconic acid, gluconolactone, glucuronic acid, glucuronolactone, glycolic acid, isopropylparaben, methylpiruvate, mucus acid, pyruvic acid, sugar acid, 1,4-lactone of a sugar acid, tartaric acid and castronova acid; beta-hydroxy acid, such as beta-hydroxybutyric acid, beta-phenylmalonate acid, beta-phenylpropanolamine acid; plant extracts, such as extracts of green tea, soybean, restore the Shi, algae, aloe, Angelica, bitter orange, coffee, coptis three leaf, grapefruit, hoellen, honeysuckle, Coix lacryma-jobi, lithospermum, mulberry, peony, puerarua, rice, safflower, and mixtures thereof.

Some preferred means of slowing the aging process, including retinoids include retinol and tretinoin, antioxidants, alpha hydroxy acid and beta hydroxy acid (Aha).

Examples of suitable protivopravnych funds include, but are not limited to, retinoids local actions, including tretinoin, isotretinoin, motretinide, adapalene, tazarotene, azelaic acid, retinol; salicylic acid; benzoyl peroxide; resorcinol; antibiotics such as tetracycline and isomers; erythromycin; anti-inflammatories, such as ibuprofen, naproxen, galprofen, plant extracts, such as extracts alder, amica, wormwood Artemisia capillaris root of wild ginger Asiasarum, placenta, calendula, chamomile, Cydia, comfrey, fennel, Galla rhois, hawthorn, Houttuynia, Hypericum, jujube, kiwi, licorice, Magnolia, European olive, peppermint, philodendron, Salvia, Sasa albomarginata; imidazoles such as ketoconazole and eluvial; such protivougrevoe funds, which are disclosed in: Gollnick, H. et al. 196 (I) Dermatology Sebaceous Glands, Acne and Related Disorders, 119-157 (1998), included in this description by reference to the extent compatible with this application; and mixtures thereof.

here are some Examples, suitable for depigmentation include retinoids such as retinol; kojic acid and its derivatives, such as dipalmitate koiwai acid; hydroquinone and its derivatives such as arbutin; transexaul acid; vitamins such as Niacin, vitamin C and its derivatives; azelaic acid; placertia; licorice; extracts such as extracts of chamomile and green tea; and mixtures thereof. Preferred retinol, kojic acid and hydroquinone.

Other examples of components that have beneficial effects include inhibitors allergies, means preventing the appearance of wrinkles, antipruritic tools, antitussives, fast hair growth, antihistamines, anticholinergics, antiemetics, antimicrobial components, vasoconstrictor tools, vasodilator, tools, accelerating wound healing, peptides, polypeptides, medicines, shaving, means on the basis of sumac, which is developing tools based Zeltennia, anti-burns, anti-diaper rash in infants, anti-tingling in thermal burns, herbal extracts, retinal, ploidy, tools, reducing the olfactory sense, conditioners for skin care remedies to lighten hair, accelerators tile is knogo exchange and similar tools, and mixtures thereof.

Other components that can be added to the compositions include typical components that are added to personal care products, all of which are applicable to enhance the appearance or cosmetic properties of the product. These may include, for example, an auxiliary thickeners, such as carboxymethylcellulose, magnesium aluminosilicate, hydroxyethylcellulose, methylcellulose, carbopol, glucamine; components with exfoliating action, such as ethylenediaminetetraacetate sodium (Na4-EDTA), EHDP or mixtures thereof, which may be present in varying amounts, including amounts in the range from about 0.01 to about 5%, preferably from about 0.01% to about 3%; and colorants, pigments, perfumes, cloud emulsions and pearlescent additives, such as zinc stearate, magnesium stearate, TiO2, EGMS (glycol monostearate) and Lytron 621 (styrene and acrylate).

In some embodiments, may be advantageously used, the inclusion of antimicrobial components. Such antimicrobial components include, for example, a simple 2-hydroxy-4,2',4'-trichlorodiphenyl ether (DP 300); preservatives, such as dimethylhydantoin (Glydant XL1000), parabens, sorbic acid and the like; antioxidants, such as bottled hydroxytoluene (BHT), and mixtures thereof.

Compositions of the invention can be obtained l is the favorite color method suitable for formation of a free flowing compositions. To create balance, providing free flowing non-Newtonian compositions of the present invention, showing the dilution when the shift amount of the electrolyte, surfactant and alkanolamide may be regulated in different ways.

Free flowing compositions of the present invention, showing non-Newtonian shear thinning shear, in some embodiments, may function as a delivery system. The quantity of the component, providing a beneficial effect subject to Association with the composition of the invention may vary, for example depending on the desired beneficial results from the sensitivity of the user to the component that have beneficial effects. Unless otherwise specified, the component that have beneficial effects, is usually present in the means of personal hygiene in the amount of from about 0,001% to about 20%, based on the total weight of free flowing composition with non-Newtonian shear thinning shear. In a preferred embodiment, component, have beneficial effects, is present in amounts in the range of from about 0,001% to about 10% relative to the weight of the composition, most preferably in the range of from about 0,001% to about 5%. Although it is expected that the composition can be IP is alsomany one or more components, have beneficial effects, the choice of component(s)that provide(s) the beneficial effects that include(s) in the composition will depend on the proposed end use of the composition and mutual compatibility of the selected ingredients that have a beneficial effect.

Compositions of the invention can also be used for the preparation of shampoos and conditioners, cleansers, compositions for delivery of cosmetics or local therapeutic agents, etc.

Compositions of the invention can be used for suspension of the components used for skin care and hair care, including, but not limited to, absorbers of ultraviolet rays, components that have a conditioning effect on the hair, components that have a conditioning effect on the hair and skin for use in means of child care, including shampoos "without tears" and baby tools for baths, components that have a conditioning effect on the skin, antimicrobial components, the polymers used in the means for stylized hair styling and care of the skin (including, for example, shampoos for washing), polymers with a conditioning effect to the means for hair care and skin precipitable polymers conditioning with de is due to the accelerated push for hair and skin, polymers with conditioning effect of high molecular masses and/or high density of cationic charge, means for care of hair and skin, surfactants, usually associated with solid compositions (such as cocoylisethionate), and nabukenya polymers, which hydratious only when applying. Compositions of the invention can also be used to obtain a stable multi-phase personal care products, including tools with painted stripes, available in formulations for body wash, shampoos for hair, natural cleansers for the skin, care of children, including shampoos "without tears"shampoos-conditioners for children and baby tools for baths, compositions for washing your face and means for skin care.

In such embodiments, where the composition of the invention containing the component that have beneficial effects, is used in the form of a shampoo, the shampoo is applied to wet hair, then the hair is washed in accordance with known practice. More preferably, the composition remains on the hair before rinsing during the time from about 0 to about 10 minutes and preferably from about 1 to about 5 minutes.

The following non-restrictive examples illustrate how a wide range of free flowing compositions with non-Newtonian shear thinning when the shift is, which can be prepared and used in accordance with the present invention.

Example 1

Typical composition

Table 1 shows the seven explanatory of examples of compositions of the present invention (No. 1-7), showing non-Newtonian shear thinning shear. It should be noted that the percentage of data without parentheses are the amounts added commercial product, and the values given in parentheses are the amounts added of the active ingredient.

The composition of table 1 include explanatory examples that include oil, softening substance or modifiers appearance. These examples are presented as typical examples and are not intended to limit the inclusion of specific additives in the concrete composition and do not mean what can be included only additive. In fact, in some embodiments it may be desirable, the inclusion of multiple types of water insoluble substances, particles, components that have beneficial effects, other optional ingredients or mixtures thereof.

Q.S.
TABLE 1
12345 67
Empicol ESB 70

(Rhodia)
70% active sodium Laureth sulphate8,15

(5,70)(1)
Rhodapex EST-30 (Rhodia)30% active tigecycline sodium48,50

(14,55)
48,50

(14,55)
47,453,253,2
Empicol BSD-52 (Albright & Wilson)52% active sodium Laureth sulphate/magnesium28,30

(14,72)
Empilan CIS (Albright & Wilson)Cocamide MIPA.2,603,003,90---
Alkamide C-4 (Rhodia)Cocamide PEG-52,9--
Alkamide C-212 (Rhodia)Cocamide MEA3,00-5,05,0
Miranol Ultra L-32

(Rhodia)
32% of the active lauroamphoacetate soda is I 15,00

(4,8)
15,00

(4,8)
14,5--
Water24,936,536,5
Empigen BB (Albright & Wilson)Laurylether0,70

(0,21)
13,00

(3,9)
Laureth-21,503,00
Glycerin1,00
Jaguar C-17 (Rhodia)Gurgitate-propylsilane-chloride0,500,50
Sodium chloride12,40

(12,00)
3,003,0016,20

(15,55)
8,65,05,0
Citric acid (to pH 4,0-6,5)Q.S.
Citric acid, 50%1,70,30,3
Sunflower oilto 6.67
Vaseline3,33
Sibione 47V600003,00
TiO20,50
Mica1,00
Looperlative additiveThe composition of "Faith" and mineral oil1,00
AppearanceOpaque liquidWhite lotionWhite lotionOpaque liquid
The temperature of the sample when measuring the viscosity24°C23°C23°C
The initial viscosity (X1000) SP7,715212016,78,510,710,3
Viscosity after 4 days freeze/thaw (F/T (X1000) SP8,5
Viscosity after 5 days F/T (X1000) SP9,6the 9.7
The viscosity after the loop F/T (X1000) SP7,816011916,6
(1)The values given in round RMS is Kah, are the quantities of the active ingredient

Example 2

The compositions and test compositions containing alkoxyalkane

To obtain a structured liquid composition with treecelleditor sodium, lauroamphoacetate sodium and sodium chloride used alkoxyalkanols (Cocamide PEG-5, Alkamide® (C-4). Basic components of this composition are presented in table 2.

/tr>
TABLE 2
ComponentWt.(g)Wt./wt.%% active connections
Rhodapex EST3068650,8115,0
Miranol Ultra L-3221015,56a 4.9
Alkamide C-4 (PEG-5 cocamide)423,113,1
Water360,826,73
50% citric acid24,21,79
Sodium chloride272,00
1350 g100,00%23,0PH between 6.08

Received and tested a number of samples containing different salt concentrations on the number of base composition table 2. The composition of the tested samples are presented below in table 3.

TABLE 3
Sample% Rhodapex EST30% Miranol Ultra L-32% Alkamide C-4% added NaClWater/inert matter %
8-150,8the 15.63,12,028,5
8-250,315,43,13,028,2
8-349,815,23,04,028,0
8-4to 49.315,13,0a 4.927,7
8-548,814,93,05,927,4
8-648,314,93,06,827,1
8-747,814,62,97,726,9
8-847,414,52,98,626,6
8-946,914.4V2,99,526,3

Measured viscosity of each of these typical compositions to a 4-day cycle of freezing/thawing and after him. The viscosity was measured using LVT No. 3, 25°C, 6 rpm for 0.5 min appearance was determined by visually observing the presence of bubbles and save the air bubbles suspended in the state before and after a cycle of freezing/thawing. Carried out the measurement only for samples that are in the original test in the centrifuge was in the form of a single phase. The results presented below in table 4 show that adding to the composition at least 8.5% of NaCl provided a stable composition. As used in this description, the term "structure" or "structured" means a system that exhibits shear thinning shear.

TABLE 4
SampleViscosity before F/TViscosity after F/TWhether the appearance structured?
8-44680-No
8-57760-No
8-6115004600 Yes
8-7130007900Yes
8-885408500Yes
8-984408860Yes

Example 3

Compositions not containing amphoteric and/or zwitterionic surfactant

The compositions containing trilateralist sodium, sodium chloride and or cocamide MEA or cocamide MIPA., examined visually for the presence of a structured appearance and viscosity loss in the cycle of freezing/thawing. In these compositions amphoteric surfactant was not used. Typical formulations used for these compositions shown below in tables 5 and 6.

TABLE 5< / br>
Basic components 9-1< / br>
Cocamide MIPA. (Empilan CIS)
ComponentWt.(g)Wt./wt.%% active connections
Rhodapex EST30278,754,6316,1
Empilan CIS265,105,1
Water191,337,49
50% citric acid1,700,33
Sodium chloride12,52,45
510,2 g100,00%of 21.2the pH of 5.4

TABLE 6< / br>
Basic components 9-2< / br>
Cocamide MEA (Alkamide® C-212)
ComponentMass.(g)Wt./wt.%% active connections
Rhodapex EST30278,754,6316,1
Alkamide® C-212265,105,1
Water191,337,50
50% citric acid1,640,32
Sodium chloride12,52,45
510,14 g100,00%of 21.2pH of 5.6

Got some samples on the basis of each of the aforementioned base compounds in tables 5 and 6 according to the respectively different salt concentrations on the number of base composition. Got a typical composition, the compositions of which are shown below in tables 7 and 8.

TABLE 7
Sample% Rhodapex EST30% Empilan CIS% added NaClWater/inert matter%
9-1-154,65,12,5of 37.8
9-1-253,85,04,037,2
9-1-353,25,05,036,8
9-1-452,7a 4.95,936,5
9-1-552,1a 4.96,936,1
9-1-651,64,87,835,8

9-2-3
TABLE 8
Sample% Rhodapex EST30% Alkamide®< / br>
C-212
% added NaClWater/inert matter%
9-2-154,65,12,5of 37.8
9-2-253,85437,2
53,25536,8
9-2-452,7a 4.95,936,5
9-2-552,1a 4.96,936,1
9-2-651,64,87,835,8

The viscosity of these compositions before and after 5-day cycle of freezing/thawing was measured in accordance with the methods specified above in example 2. The results are shown below in table 9. As shown below in table 9, data on viscosity and appearance before and after a cycle of freezing/thawing for the compositions of tables 7 and 8 show that the stable composition of the above compositions can be obtained by adding 5% or more of sodium chloride.

td align="center"> Single phase
TABLE 9
SampleThe original appearanceThe initial viscosityViscosity after F/TWhether the appearance structured?
9-1-1Transparency 25%---
9-1-2Single phase118001540No
9-1-3102809700Yes
9-1-4Single phase966011300Yes
9-1-5Single phase948011760Yes
9-1-6Single phase60009200Yes
9-2-1Transparency 15%---
9-2-2Single phase133603000No
9-2-3Single phase107209600Yes
9-2-4Single phase946011900Yes
9-2-5Single phase800012200Yes
9-2-6Single phase230010400Yes

Example 4

Compositions and study the influence of increasing levels of alkanolamide

To create a structured liquid composition with treecelleditor sodium, lauroamphoacetate sodium and sodium chloride used Alkamide® C-212 (cocamide MEA). The compositions of typical compositions are presented below in table 10.

TABLE 10
Sample% Rhodapex EST30% Alkamide®< / br>
C-212
% Miranol Ultra L-32% NaCl% waterthe pH after adding citric acid
10-147,6014,72,035,75,8
10-247,61,014,72,0to 33.85,8
10-347,62,014,72,032,85,88
10-447,62,914,72,0of 31.8of 5.82
10-547,6a 3.914,72,030,8of 5.75
10-647,6a 4.914,72,029,95,9
10-747,65,914,72,028,95,86

The viscosity was measured before and after a one-day cycle of freezing/thawing in accordance with the methods presented in example 2, the results are summarized below in table 11. As follows from the ablity 11, data viscosity and appearance before and after the cycle (1 day) freeze/thaw for the compositions of table 10 show that in the presented examples, a stable composition can be obtained with the addition of 3% or more cocamide MEA.

TABLE 11
SampleViscosity before F/TViscosity after F/TAppearance
10-1800400Turbidity 75%
10-234003600Muddy
10-338004100Muddy
10-459006400The increase in turbidity
10-575007100The increase in turbidity
10-687009000The increase in turbidity
10-71100011500The increase in turbidity

Example 5

The preparation of compositions

Methods of obtaining compositions exhibiting non-Newtonian shear thinning shear, can be changed in accordance with the physical properties of a particular composition.

A typical way to obtain systems with Pont is defined viscosity, containing solids, such as compositions 1 and 4 of table 1, is as follows: all surface-active substances (i.e. surfactants), including alkanolamide, was added to the water under moderate agitation with agitation. When used solid surfactant, the mixture was heated to a temperature of at least 5-10°C above the melting temperature of the solid surface-active substance. The mixture was stirred until, when they became homogeneous, and when used heat, stirring is continued until cooling the mixture to ambient temperature. Then brought the pH to a value of from about 5.5 to 6.5 and under stirring to the dispersion was added to the electrolyte and a solid component, providing a beneficial effect.

A typical method include emollients in systems with high viscosity, such as compositions 2 and 3 of the above table 1 is as follows. First, water was added to the cationic polymer. The addition was carried out either prior solubilization of cationic polymer in the glycerin, or by adding a cationic polymer directly to the water and bring the pH to 4-5. Added anionic surfactant and the secondary surfactant or ingredients (other than amphoteric and/or zwitterionic surface is active substances and alkanolamide) and the mixture was heated to about 65-80° With, for example, to a temperature above the melting temperature used alkanolamide. Then added alkanolamide and the composition was stirred with a stirring speed of 200-400 rpm using a mechanical stirrer shaft, which includes two (2) of the impeller, each with four inclined blades, and the sharp end of each blade is inclined more strongly than the Central part, and the sharp end of each blade is moved alternately up and down. The temperature, at least above the melting point alkanolamide 5-10°maintained up until the system became homogeneous. Softening substance was heated to a temperature of about 60-65°and added to the surfactant mixture as soon as the surface-active mixture reached approximately the same temperature, that is about 60-65°C. the mixture is Then cooled to 30-35°and, if used amphoteric and/or zwitterionic surfactant, was added at the beginning of the cooling process. When he reached the temperature of 30-35°C, pH was brought citric acid and added supplements, sensitive to heat, such as coloring, flavoring and preservatives, as well as the electrolyte. After adding electrolyte stirring was continued for at least 1-2 hours. Received generally from 500 g to 1000 g each load.

the illusion in this field will understand, what the present invention has a wide range of usefulness and applications. Many variations and modifications of the invention, including various methods of preparing compositions of the present invention, other than those disclosed in this description, as well as many changes and modifications will be apparent from a reasonable proposed in the present invention and the preceding description without deviating from the essence or scope of the present invention. Accordingly, although the present invention is described in detail in typical embodiments, it should be understood that this description is only explanatory and illustrative example of the present invention and is used only for the purpose of ensuring full and possible disclosure of the invention. The foregoing is not intended to limit the invention, or it should not be interpreted as limiting the present invention or exclude any other options, alterations, changes, modifications, while the present invention is limited only by the attached claims and their equivalents.

1. Water free flowing composition comprising, based on the weight of the composition

(a) at least one anionic surfactant in an amount of from about 5 to about 30%;

(b) at least one alkanolamide in the number is the firmness of from 0.1 to about 10%;

(c) at least one electrolyte;

(d) optionally, one or more additional surfactants selected from the group consisting of nonionic, amphoteric and zwitterionic surfactants; and

(e) water,

in which at least one of the components (a), (b) and (d) has an aliphatic chain, which has a branching, saturation, or a combination thereof, and these, at least one anionic surfactant, at least one alkanolamine and at least one electrolyte is present in such total amount that the composition has a lamellar liquid crystal structure, has the property of non-Newtonian shear thinning and stable viscosity, at least one cycle of freezing/thawing, and is capable of suspending the water-insoluble particles or partially insoluble components.

2. The composition according to claim 1, where the composition contains, based on the weight of the composition, from 1 to 20% of one or more additional surfactants selected from the group consisting of nonionic, amphoteric and zwitterionic surfactants or combinations thereof.

3. The composition according to claim 1, additionally containing at least one compound selected from the group, ostoja essentially of water insoluble particles, partially insoluble components and components that have beneficial effects, suspended in the composition.

4. Free flowing composition according to claim 1, where the initial viscosity, free flowing composition is equal to or exceeds 3000 SP.

5. Free flowing composition according to claim 1, where the free flowing composition is stable for at least three cycles of freezing/thawing.

6. Free flowing composition according to claim 1, where at least one anionic surfactant selected from the group consisting of surfactants having a branched aliphatic chain, unsaturated aliphatic chain, and combinations thereof.

7. Free flowing composition according to claim 1 where the anionic surfactant is trilateralist sodium.

8. Free flowing composition according to claim 1, where alkanolamide selected from the group consisting of alkanolamides having a branched aliphatic chain, unsaturated aliphatic chain and their combinations.

9. Free flowing composition according to claim 1, where alkanolamine represented by the formula

where R represents a C8-C24saturated or unsaturated aliphatic group with a straight or branched chain, R1and R2are the same or different, C2-C 4aliphatic gruppe straight or branched chain, x is equal to from 0 to 10, y is from 1 to 10 and the sum of x and y is less than 10 or equal to 10.

10. Free flowing composition according to claim 1, where at least one additional surfactant includes lauroamphoacetate sodium.

11. The composition according to claim 1, where the composition contains, based on the weight of the composition, from 0.1 to 15 wt.% at least one electrolyte.

12. The composition according to claim 1, where at least one anionic surfactant is from about 10 to about 20 wt.% relative to the weight of the composition, the amount of at least one alkanolamide is at least from about 2 to about 5 wt.% relative to the weight of the composition and quantity of at least one electrolyte comprises at least from about 1 to about 6 wt.% relative to the weight of the composition.

13. The composition according to claim 3, where component providing a beneficial effect selected from the group consisting of protivoprigarnykh components, pigments or cloud emulsions, moisturizing beads, natural abrasives, synthetic abrasive materials, such as polyoxyethylene balls, sunscreen, vegetable oils, animal fats, mineral oils, petrolatum, silicone oils, polyallylamine, polyalkyl is siloxane, esters, fatty acids and alcohols, means for depigmentation, reflectors, absorbers of ultraviolet rays, thickening components, means for moistening and easy combing hair, film-forming polymers, water-retaining substances, amino acids and their derivatives, antimicrobial components, protivopravnych funds of funds, slow aging, antiseptics, analgesics, local anesthetics, anti hair loss, inhibitors of hair growth, anti-inflammatory drugs, protein, deodorants and antiperspirants; preparations for treatment of dandruff, seborrheic dermatitis and psoriasis, mitigating cosmetic substances for skin, skin moisturizers, conditioners hair, hair softeners, humidifiers, hair vitamins, components, contributing to tan, components, whitening skin, antifungal agents, tools for hair removal, components against skin irritation, the funds used for hemorrhoids, insecticides, sunscreens and mixtures thereof.

14. Free flowing composition according to item 13, where protivopekhotnymi component selected from the group consisting of zinc-pyrithione and mica.

15. Free flowing composition according to item 13, where the vegetable oil is selected from the group consisting of peanut oil, castor oil, cocoa butter, coconut oil, kukuruznik the oil, cottonseed oil, olive oil, palm kernel oil, rapeseed oil, safflower oil, sesame oil and soybean oil.

16. Free flowing composition according to item 13, where the ester is selected from the group consisting of butylmalonate, cetylpalmitate, decollete, literallayout, glyceryltrinitrate, glycerylmonostearate, glycerylmonostearate, vexillata, isobutylacetate, societystate, isopropylacetate, Isopropylamine, isopropylmalate, isopropylmyristate, isopropylpalmitate, isopropylmalate, monolaurate propylene glycol, ricinoleate propylene glycol, propylene glycol stearate and isostearate propylene glycol, vegetable oil selected from the group consisting of peanut oil, castor oil, cocoa butter, coconut oil, corn oil, cottonseed oil, olive oil, palm kernel oil, rapeseed oil, safflower oil, sesame oil and soy oil.

17. Free flowing composition according to item 13, where animal fat selected from the group consisting of acetylated lanolin alcohols, lanolin, lard, mink oil and tall oil.

18. Free flowing composition according to item 13, where fatty acid and an alcohol selected from the group consisting of beganovi acid, palmitic acid, stearic acid, BeginInvoke alcohol, cetyl alcohol, ahsanullah Speer is a, isoreticular alcohol.

19. The composition according to item 13, where the component that have beneficial effects, is an absorber of ultraviolet rays, useful in applications for care of the skin to protect the skin from ultraviolet light.

20. The composition according to item 13, where the component that have beneficial effects, is an absorber of ultraviolet rays, useful in applications for care of hair to protect hair from UV light.

21. The composition according to item 13, where the component that have beneficial effects, is a hair conditioner.

22. The composition according to item 21, where hair conditioner selected from the group consisting of silicones, silicone derivatives, natural oils, nonionic surfactants, waxes, synthetic oils, cationogenic surfactants and polymers.

23. The composition according to item 13, where the component, providing a beneficial effect selected from the group consisting of air conditioners for hair and skin, designed to care for children.

24. The composition according to item 23, where the component, providing a beneficial effect selected from the group consisting of silicones, silicone derivatives, natural oils, nonionic surfactants, waxes, synthetic oils, cationogenic surfactant in the substances and polymers.

25. The composition according to item 23, where the means to care for children selected from the group consisting of shampoo, "no tears"shampoo-conditioner for children, and the means for bathing.

26. The composition according to item 13, where the component, providing a beneficial effect selected from the group consisting of means for skin care and ingredients that have a conditioning effect on the skin.

27. The composition according to p, where component providing a beneficial effect selected from the group consisting of salicylic acid, alpha hydroxy acids, vitamins, vitamins, abrasives, silicones, silicone derivatives, natural oils, synthetic oils and polymers.

28. The composition according to item 13, where the component, providing a beneficial effect selected from the group consisting of antimicrobial components.

29. The composition according to p, where the antimicrobial component is selected from the group consisting of triclosan, trichlorsilane, chlorhexidinegluconate, zinc-pyrithione, a pair of chlormethiazole and selenium sulphide.

30. The composition according to item 13, where the component that have beneficial effects, contains polymers for stylized hair styling.

31. The composition according to item 13, where the component, providing a beneficial effect selected from the group consisting of polymers with conditioning effect of high molecular masses, and poly is ' with conditioning effect, with a high density of cationic charge.

32. The composition according to item 13, where the component that have beneficial effects, includes precipitated polymer with a conditioning effect.

33. The composition according to item 13, where the component that have beneficial effects, includes a surfactant, usually associated with hard structures.

34. The composition according to p, where the surfactant includes cocoylisethionate.

35. The composition according to item 13, where the component that have beneficial effects, includes nabuhay polymer, such as hydrated only in the application.

36. Stable multi-phase composition in the form of personal care products containing the composition according to claim 1.

37. The composition in the form of personal care products on p, where the composition is selected from the group consisting of the compounds for body wash with stripes, shampoos for hair cleansers, compositions in the form of funds for child care formulations facial wash and compositions for skin care.

38. The way to obtain water free flowing composition, including mixing, based on the weight of the composition

(a) at least one anionic surfactant in an amount of from about 5 to about 30%;

(b) at least one alkanolamide in the amount of from 0.1 to about 10%;

(c) at least one the first electrolyte; and

(d) optionally, one or more additional surfactants selected from the group consisting of nonionic, amphoteric and zwitterionic surfactants; and

(e) water,

where at least one of the components (a), (b) and (d) has an aliphatic chain, which has a branching, unsaturation, or a combination thereof, and these, at least one anionic surfactant, at least one alkanolamine and at least one electrolyte is present in such total amount that the composition has a lamellar liquid crystal structure, has the property of non-Newtonian shear thinning and stable viscosity, at least one cycle of freezing/thawing, and can not suspended the water-soluble particles or partially insoluble components.

39. The method according to 38, additionally comprising introducing into the composition, of at least one compound selected from the group consisting essentially of water-insoluble particles partially insoluble components and components that have beneficial effects.

40. The method according to 39, where the at least one connection is a solid.

41. The method according to 39, where the at least one connection is particularly the liquid.

42. The method according to 39, where the at least one connection is gas.

43. Water free flowing composition comprising, based on the weight of the composition, essentially from

(a) at least one anionic surfactant in an amount of from about 5 to about 30%;

(b) at least one alkanolamide in the amount of from 0.1 to about 10%;

(c) at least one electrolyte;

(d) optionally, one or more additional surfactants selected from the group consisting of nonionic, amphoteric and zwitterionic surfactants; and

(e)water,

in which at least one of the components (a), (b) and (d) has an aliphatic chain, which has a branching, unsaturation, or a combination thereof, and these, at least one anionic surfactant, at least one alkanolamine and at least one electrolyte is present in such total amount that the composition has a lamellar liquid crystal structure, has the property of non-Newtonian shear thinning and stable viscosity, at least one cycle of freezing/thawing, and is capable of suspending the water-insoluble particles or partially insoluble components.

44. Comp is the position of item 43, where the composition contains, based on the weight of the composition, from 1 to 20% of one or more additional surfactants selected from the group consisting of nonionic, amphoteric and zwitterionic surfactants or combinations thereof.

45. The composition according to item 43, additionally containing at least one compound selected from the group consisting essentially of water-insoluble particles partially insoluble components and components that have beneficial effects, suspiciously in composition.

46. Free flowing composition according to item 43, where the initial viscosity, free flowing composition is equal to or exceeds 3000 SP.

47. Free flowing composition according to item 43, where free flowing composition is stable for at least three cycles of freezing/thawing.

48. Free flowing composition according to item 43, where at least one anionic surfactant selected from the group consisting of surfactants having a branched aliphatic chain, unsaturated aliphatic chain, and combinations thereof.

49. Free flowing composition according to item 43, where alkanolamide selected from the group consisting of alkanolamides having a branched aliphatic chain, unsaturated aliphatic chain, and combinations thereof.

50. The composition according to item 43, g is e, the composition contains, based on the weight of the composition, from about 0.1 to about 15 wt.% at least one electrolyte.

51. The composition according to item 43, where the amount of at least one anionic surfactant is from about 10 to about 20 wt.% relative to the weight of the composition, the amount of at least one alkanolamide is at least from about 2 to about 5 wt.% relative to the weight of the composition and quantity of at least one electrolyte comprises at least from about 1 to about 6 wt.% relative to the weight of the composition.

52. The composition according to item 45, where the component, providing a beneficial effect selected from the group consisting of protivoprigarnykh components, pigments or cloud emulsions, moisturizing beads, natural abrasives, synthetic abrasive materials, such as polyoxyethylene balls, sunscreen, vegetable oils, animal fats, mineral oils, petrolatum, silicone oils, polyallylamine, polyalkylacrylate, esters, fatty acids and alcohols, means for depigmentation, reflectors, absorbers of ultraviolet rays, thickening components, means for moistening and easy combing hair, film-forming polymers, water-retaining substances, amino acids and their derivatives, antimicrobial compound is, protivopravnych funds of funds, slow aging, antiseptics, analgesics, local anesthetics, anti hair loss, inhibitors of hair growth, anti-inflammatory drugs, protein, deodorants and antiperspirants; preparations for treatment of dandruff, seborrheic dermatitis and psoriasis, mitigating cosmetic substances for skin, skin moisturizers, hair conditioners, softeners, hair, hair moisturizers, vitamins, components, contributing to tan, components, whitening skin, antifungal agents, tools for hair removal, components against skin irritation, the funds used for hemorrhoids, insecticides, sunscreen and mixtures thereof.

53. The composition according to claim 5, where the aforementioned at least one anionic surfactant is a branched alkyl chain.

54. The composition according to claim 1, where the aforementioned at least one anionic surfactant contains alkylsulfate or esterified alkylsulfate formula RO(CH2CH2O)nSO3M, where R is tridecyl, n has an average value from 0 to 7, and M represents solubilizers cation.



 

Same patents:

FIELD: detergents.

SUBSTANCE: invention provides detergent that can be used in all industrial areas wherein surfaces may be polluted by organic-origin products (oil, grease, crude oil, emulsions, asphalt-tar-paraffin deposits), for instance in production processes and equipment restoration, including mechanical engineering, transport, service centers, agricultural farms. Detergent contains, wt %: "sinterol" 10-12, sodium metacilicate (liquid glass) 2-5, sodium tripolyphosphate or trisodium phosphate 15-20, bactericidal-anticorrosive additive 3-5, and calcium carbonate to 100%. Bactericidal-anticorrosive additive is quaternary ammonium salt obtained by reaction of N,N-tetramethyldiaminomethane with alkyl- and alkenyl chlorides. Thus obtained detergent possesses a complex of useful physicochemical properties: dissolving, moistening, degreasing, emulsifying, and anticorrosive capabilities.

EFFECT: improved consumer properties, extended application area, and reduced consumption of detergent.

3 cl, 2 tbl, 6 ex

Synthetic detergent // 2259392

FIELD: detergents.

SUBSTANCE: detergent applicable for washing and watering of all types of textiles both under domestic conditions and in industrial contains, wt %: surfactants 1-14, sodium tripolyphosphate 20-30, sodium liquid glass 3, carboxymethylcellulose 0.5-0.8, polycarboxylate "Akremon" 0.1-1.5, soda ash 5-10, optical bleacher 0.2-0.3, odorant 0.05-0.1, sodium chloride 0.5-4.0, oxyethylated isononylphenol/triethanolamine/sodium hydroxide interaction product 1-14, water and sodium sulfate to 100%. Detergent may further contain of nonionic surfactants 0-3, sodium bicarbonate 0-5, polyvinylpyrrolidone 0-0.3, and foam suppressor 0-0.2.

EFFECT: enhanced detergent effect and acquired softening effect.

8 cl, 2 tbl, 8 ex

The invention relates to detergents for cleaning metal surfaces and can be used to remove contaminants from the surface in mechanical production and to prepare the surface before applying paint coatings in the automotive industry

The invention relates to the industrial production of detergents or detergents, and more particularly to a composition of amorphous alkali metal silicate, obtained by spray drying with the secondary cleaning effect, the cleaning tool or detergent and extruded cleaning tool or detergent containing the composition

FIELD: organic chemistry, medicine, pharmacy, cosmetology.

SUBSTANCE: invention relates to novel biphenylmethylthiazolidinedions of the general formula (I): , their salts, and to their optical and geometrical isomers possessing agonistic activity with respect to PPARγ receptors, to pharmaceutical and cosmetic compositions based on thereof, and to their using for preparing composition used in treatment of different cutaneous diseases. In compound of the formula (I) R1 means radical of the following formula (a): or (b): ; R2 and R3 mean hydrogen atom; X means binding groups showing the following structures: -CH2-N(R8)-CO-, -N(R8)-CO-N(R9)- that can be read from left to right or vice versa; R4 means phenyl substituted with group R10, pyrrolyl, naphthyl, biphenyl, indenyl, benzothienyl and all these groups can be mono- or di-substituted with group R11 and/or R12, group -(CH2)n-(CO)qR13, adamantyl, cyclopentylethyl, group -(CH2)n-O-R13; R5 means hydroxyl or alkoxyl with 1-19 carbon atoms; R6 means group -OR14. Values R8, R9, R10, R11, R12, R13, n and q are given in the invention claim.

EFFECT: valuable medicinal properties of compounds.

25 cl, 2 dwg, 37 ex

FIELD: organic chemistry, medicine, pharmacy, cosmetology.

SUBSTANCE: invention relates to novel biphenylmethylthiazolidinedions of the general formula (I): , their salts, and to their optical and geometrical isomers possessing agonistic activity with respect to PPARγ receptors, to pharmaceutical and cosmetic compositions based on thereof, and to their using for preparing composition used in treatment of different cutaneous diseases. In compound of the formula (I) R1 means radical of the following formula (a): or (b): ; R2 and R3 mean hydrogen atom; X means binding groups showing the following structures: -CH2-N(R8)-CO-, -N(R8)-CO-N(R9)- that can be read from left to right or vice versa; R4 means phenyl substituted with group R10, pyrrolyl, naphthyl, biphenyl, indenyl, benzothienyl and all these groups can be mono- or di-substituted with group R11 and/or R12, group -(CH2)n-(CO)qR13, adamantyl, cyclopentylethyl, group -(CH2)n-O-R13; R5 means hydroxyl or alkoxyl with 1-19 carbon atoms; R6 means group -OR14. Values R8, R9, R10, R11, R12, R13, n and q are given in the invention claim.

EFFECT: valuable medicinal properties of compounds.

25 cl, 2 dwg, 37 ex

FIELD: medicine, dermatology.

SUBSTANCE: the present innovation deals with applying the preparation to prevent contact allergic dermatitis induced with salts of nickel or other metals under conditions of nickel plating at galvanic manufacturing. The preparation for preventing contact allergic dermatitis induced with nickel salts contains natural zeolite (for example, from Kholinskoe origin at isolated fraction being less than 0.25 mm). It consists of zeolite dispersed in the foundation out of starchy gel at the following ratio of the components, weight%: zeolite 26.0-29.0; 2.0-4.0 weight% starchy gel - the rest. The preparation declared is of good sorption properties, covers the skin steadily and is retained well upon it; it is easily removed with water that in combination enables to decrease the quantity of nickel ions in surface and deep cutaneous layers and, thus, prevents the development of contact dermatosis.

EFFECT: higher efficiency of prophylaxis.

3 ex, 1 tbl

FIELD: medicine, stomatology.

SUBSTANCE: the present innovation deals with taking care of oral cavity. The suggested composition includes 0.01-20 weight% of finely divided natural chalk and about 5-60 weight% perlite. The innovation produces improved abrasive result.

EFFECT: higher efficiency.

3 cl, 2 ex

FIELD: cosmetology.

SUBSTANCE: the present innovation refers to cosmetic preparations and deals with antiperspirants and deodorants. Emulsion composition of water/salt of antiperspirant contains dissolved astringent salt chosen out of the salts of aluminum, zirconium and mixed salts of aluminum-zirconium, an emulsifying agent and, in separate phase, a polymer containing the groups of Brönsted acids. The suggested composition enables to decrease perspiration.

EFFECT: higher efficiency.

9 cl, 8 ex, 6 tbl

FIELD: medicine, stomatology.

SUBSTANCE: invention discloses a substrate containing about from 5 wt.-% to 30 wt.-% of added gum. Also, invention discloses a method for preparing a substrate with added or applied gum. Also, invention involves agent for teeth care and comprising a gum-treated substrate and one or more components chosen from group consisting of wetting agents, abrasives, thickening agents, binding agents, stabilizing agents, bactericidal agents, fluorides, sweetening agents and surfactants. Invention provides delayed increasing viscosity in addition of substrate to the personal hygiene composition, such as dental paste.

EFFECT: improved method of addition.

13 cl, 4 tbl, 10 ex

FIELD: industrial hygiene.

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EFFECT: improved and valuable properties of cream.

7 cl, 2 tbl

Powder-deodorant // 2322229

FIELD: cosmetology, medicine, hygiene.

SUBSTANCE: invention relates to curative-prophylactic agents designated for care and improving the physiological state of body, hands and legs skin. Proposed powder-deodorant for skin comprises cation-substituted forms of natural zeolite, filling agents and cosmetic additives. As a cation-substituted form of zeolite powder-deodorant comprises Na-form and hydrophobic form of natural zeolite taken in the ratio from 1:10 to 10:1. Components are taken in the definite quantitative content. Proposed powder provides possibility for the more removal of fat and/or salts secreted with sweat being among them heavy metal salts, ammonia, decreasing superdrying skin in multiple using powder-deodorant, and cosmetic properties directed for protection and improving the physiological state and skin breathing.

EFFECT: improved and valuable properties of powder-deodorant.

4 cl, 5 ex

Powder-deodorant // 2322229

FIELD: cosmetology, medicine, hygiene.

SUBSTANCE: invention relates to curative-prophylactic agents designated for care and improving the physiological state of body, hands and legs skin. Proposed powder-deodorant for skin comprises cation-substituted forms of natural zeolite, filling agents and cosmetic additives. As a cation-substituted form of zeolite powder-deodorant comprises Na-form and hydrophobic form of natural zeolite taken in the ratio from 1:10 to 10:1. Components are taken in the definite quantitative content. Proposed powder provides possibility for the more removal of fat and/or salts secreted with sweat being among them heavy metal salts, ammonia, decreasing superdrying skin in multiple using powder-deodorant, and cosmetic properties directed for protection and improving the physiological state and skin breathing.

EFFECT: improved and valuable properties of powder-deodorant.

4 cl, 5 ex

FIELD: medicine, disinfection.

SUBSTANCE: the present innovation refers to preparations indicated for treating the skin of hands and removing contaminations while carrying out works under industrial and household conditions. The suggested preparation contains a surface-active substance, glycerol, kaolin, water-soluble ethers of cellulose, natural polysaccharides, citric acid and water. Due to empirically matched composition of the ingredients it has been provided the increase of purifying capacity of the present preparation at keeping stable viscosity characteristics for the whole storage period. The suggested preparation efficiently protects and purifies hands against spots of general technical and household nature, removes radioactive contaminations from hands' skin, avoids skin drying and chapping in case of frequent usage, it is easily applied and removed and keeps hands clean, soft and aromatic.

EFFECT: higher efficiency of disinfection.

3 cl, 3 tbl

FIELD: organic chemistry, medicine, pharmacy, cosmetology.

SUBSTANCE: invention relates to novel biphenylmethylthiazolidinedions of the general formula (I): , their salts, and to their optical and geometrical isomers possessing agonistic activity with respect to PPARγ receptors, to pharmaceutical and cosmetic compositions based on thereof, and to their using for preparing composition used in treatment of different cutaneous diseases. In compound of the formula (I) R1 means radical of the following formula (a): or (b): ; R2 and R3 mean hydrogen atom; X means binding groups showing the following structures: -CH2-N(R8)-CO-, -N(R8)-CO-N(R9)- that can be read from left to right or vice versa; R4 means phenyl substituted with group R10, pyrrolyl, naphthyl, biphenyl, indenyl, benzothienyl and all these groups can be mono- or di-substituted with group R11 and/or R12, group -(CH2)n-(CO)qR13, adamantyl, cyclopentylethyl, group -(CH2)n-O-R13; R5 means hydroxyl or alkoxyl with 1-19 carbon atoms; R6 means group -OR14. Values R8, R9, R10, R11, R12, R13, n and q are given in the invention claim.

EFFECT: valuable medicinal properties of compounds.

25 cl, 2 dwg, 37 ex

FIELD: organic chemistry, medicine, pharmacy, cosmetology.

SUBSTANCE: invention relates to novel biphenylmethylthiazolidinedions of the general formula (I): , their salts, and to their optical and geometrical isomers possessing agonistic activity with respect to PPARγ receptors, to pharmaceutical and cosmetic compositions based on thereof, and to their using for preparing composition used in treatment of different cutaneous diseases. In compound of the formula (I) R1 means radical of the following formula (a): or (b): ; R2 and R3 mean hydrogen atom; X means binding groups showing the following structures: -CH2-N(R8)-CO-, -N(R8)-CO-N(R9)- that can be read from left to right or vice versa; R4 means phenyl substituted with group R10, pyrrolyl, naphthyl, biphenyl, indenyl, benzothienyl and all these groups can be mono- or di-substituted with group R11 and/or R12, group -(CH2)n-(CO)qR13, adamantyl, cyclopentylethyl, group -(CH2)n-O-R13; R5 means hydroxyl or alkoxyl with 1-19 carbon atoms; R6 means group -OR14. Values R8, R9, R10, R11, R12, R13, n and q are given in the invention claim.

EFFECT: valuable medicinal properties of compounds.

25 cl, 2 dwg, 37 ex

FIELD: medicine, dermatology.

SUBSTANCE: the present innovation deals with applying the preparation to prevent contact allergic dermatitis induced with salts of nickel or other metals under conditions of nickel plating at galvanic manufacturing. The preparation for preventing contact allergic dermatitis induced with nickel salts contains natural zeolite (for example, from Kholinskoe origin at isolated fraction being less than 0.25 mm). It consists of zeolite dispersed in the foundation out of starchy gel at the following ratio of the components, weight%: zeolite 26.0-29.0; 2.0-4.0 weight% starchy gel - the rest. The preparation declared is of good sorption properties, covers the skin steadily and is retained well upon it; it is easily removed with water that in combination enables to decrease the quantity of nickel ions in surface and deep cutaneous layers and, thus, prevents the development of contact dermatosis.

EFFECT: higher efficiency of prophylaxis.

3 ex, 1 tbl

FIELD: medicine, stomatology.

SUBSTANCE: the present innovation deals with taking care of oral cavity. The suggested composition includes 0.01-20 weight% of finely divided natural chalk and about 5-60 weight% perlite. The innovation produces improved abrasive result.

EFFECT: higher efficiency.

3 cl, 2 ex

FIELD: cosmetology.

SUBSTANCE: the present innovation refers to cosmetic preparations and deals with antiperspirants and deodorants. Emulsion composition of water/salt of antiperspirant contains dissolved astringent salt chosen out of the salts of aluminum, zirconium and mixed salts of aluminum-zirconium, an emulsifying agent and, in separate phase, a polymer containing the groups of Brönsted acids. The suggested composition enables to decrease perspiration.

EFFECT: higher efficiency.

9 cl, 8 ex, 6 tbl

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