Method for treating patients after removing gallbladder
SUBSTANCE: method involves prescribing conservative training motor activity and feeding diet No 5 with low mineralization low carbonic acid concentration sulfate and hydrocarbonate sodium-calcium mineral water being taken. Mineral water baths with low mineralization low carbonic acid concentration sulfate and hydrocarbonate sodium-calcium mineral water are given at 36-37°C during 12-15 min with 8-10 procedures per treatment course. 2.5% succinic acid solution electrophoresis is additionally applied to interscapular zone from cathode with the other washer - anode being placed on liver and right hypochondrium projection zone using current of 15-25 mA during 15-25 min daily with 10-12 procedures per treatment course.
EFFECT: reduced intensity of digestion disorder syndrome manifestation; stabilized peroxide homeostasis; increased organism adaptation capability.
The method relates to the field of medicine, namely to the section of gastroenterology, and for the treatment of physical factors in patients with biliary tract disease.
Development of methods of treatment of patients after cholecystectomy is an actual problem of modern medicine. The prevalence of gallstone disease and, accordingly, increase in the number of cholecystectomies, reduce disability and quality of life of patients who underwent surgery necessitates the search for effective treatments for this disease. Polyorgano lesions of the digestive system after the operation, the complexity of their pathogenesis and diversity of clinical manifestations, combine the collective term "post-cholecystectomy syndrome, cause difficulty in achieving a therapeutic effect, and the treatment is mainly symptomatic.
There is a method of treatment of patients after cholecystectomy using atraumatic-training regimen physical activity, diet, intake of mineral water, mineral baths when water temperature is 36-37°C for 12-15 minutes, 8-10 treatments of treatment (Balneology and physiotherapy, 1985, Vol.2). This method of treatment is the prototype for this invention.
However, this method is not effektivnym in respect of correction of the disturbed digestion and energy metabolism as manifestations of disorders of adaptive reactions of the organism of patients in new anatomical and physiological conditions, formed after removal of the gall bladder.
These scientific observations and practical work of physicians and health centers indicate that even when assigning adequate from a clinical point of view of medical facilities at the resort are negative results - indigestion with the development of diarrhea, increased clinical manifestations of opportunistic diseases, developed prior to surgery or after it (pancreatitis, duodenal dyskinesia, peptic ulcer, gastroesophageal reflux disease). This fact can be explained by the fact that the appointment of a patient care is carried out without taking into consideration existing in these patients disorders of adaptation processes and energy metabolism.
The technical result of the proposed method is to increase the effectiveness of rehabilitation treatment after removal of the gallbladder through the correction of disturbed digestion, reduced adaptive reserves of the body of patients and the energy exchange in new anatomical and physiological conditions after surgery. This technical result is achieved by the fact that in complex therapy used electrophoresis of succinic acid as a method of complex influence of galvanic current on his background - input foretical by succinic acid - one of the substrates oxide what s in the Krebs cycle, contribute to the improvement of energy metabolism in the body.
The method is performed as follows: patients within the first 3 days of stay at the resort designate the mode with limited motor activity as one of the elements of adaptation and recovery of energy resources of the organism by reducing energy consumption. In the subsequent motor activity is replaced by the gentle and atraumatic-training. Diet nutrition diet №5. Assigned internal reception mineral water Slavophiles hydrocarbonate-sulphate-sodium-calcium, low-salinity (Slavyanovskaya) at a temperature of 55°starting with small doses on 120,0-150,0 ml per one scoop (2.5 g per 1 kg of patient's body weight), leading to a dose of 3.3 g of water per 1 kg of patient's body weight (200,0-of 250.0 ml per admission) for 3-4 days. Mineral water they take 45 minutes before a meal.
Mineral baths are appointed when the water temperature is 36-37°C for 12-15 minutes, every day, 8-10 treatments on the course of treatment.
With the purpose of correcting existing patients after cholecystectomy violations adaptation processes and energy metabolism appoint electrophoresis of succinic acid, which is carried out as follows: the hydrophilic spacer cathode (-) area of 250-280 cm2impregnated with a 2.5% solution of succinic acid which you have in the interscapular region (D 4-D10segments), strip anode (+) area of 200 cm2impregnated with tap water and placed on the region of the liver and right hypochondrium. Current 15-25 mA (when the light burning sensation under the electrodes), the duration of the treatment 15-25 minutes (gradually increasing in the early days of treatment), exposure is performed daily in the treatment of 10-12 procedures. The methodology is data about important therapeutic role of the influence of galvanic current and succinic acid (substrate oxidation in the Krebs cycle), moreover, that in this category of patients identified disorders of energy metabolism (see data table 2). The location of the electrodes is caused by the need to influence both the overall health and functional status of the liver.
The method can be explained by the following examples.
Patient TLV, 47 years old, medical history, No. 446. Diagnosis at admission: ECB. Cholecystectomy in 1998 Chronic biliarsky pancreatitis in the phase of incomplete remission. Upon receipt complained of expressed General weakness, fatigue, headache, bitter taste in the mouth, nausea, aching pain in the upper abdomen, change of constipation by softening the stool.
Palpation of the abdomen is marked moderately severe pain in the right hypochondrium and epigastrium. Liver invoice is Paeth from under the edge of the costal arch by 1.5-2 cm, sensitive to palpation. Blood count; white blood cell count - 4·109/l, lymphocytes - 22%, neutrophils - 68%, monocytes - 10%, eosinophils - 0. Blood bilirubin - 12.1 µmol/l, cholesterol - 8.4 mmol/l, alkaline phosphatase - 156 u/l, the level of MDA in plasma were 1,268 µmol/l Detected overall energy deficit: the level of ATP in erythrocytes - 508 μmol/l AMP - 68 µmol/l, the energy charge is 0.80, the LDH activity in lymphocytes - 1055 units and GFDG - 530 units of lactate - 1,89 mmol/l pyruvate - 0,966 mmol/L. treatment - regimen physical activity sparing, meals according to the diet №5, internal intake of the mineral water source Slavyanovskaya", mineral baths (8), electrophoresis of 2.5% solution of succinic acid by the method described above, 10 sessions of treatment. At discharge from the hospital had no complaints, pain abdominal palpation was not determined. The size of the liver decreased to the normal range. Survey data after treatment: the number of leukocytes - 4,6·109/l, lymphocytes - 27%, neutrophils - 65%, monocytes - 5%, eosinophils - 2%. Blood bilirubin - 10.1 µmol/l, cholesterol - 4.4 mmol/l, alkaline phosphatase - 136 u/l, the level of MDA in plasma - kgs 1,090 µmol/l, ATP in erythrocytes - 584 μmol/l AMP - 38 µmol/l, the energy charge - 0,89% the Activity of LDH - 1090 units and GFDG - 570 units, lactate - 1,36 mmol/l pyruvate - 0.061 mmol/L. Thus, the p is vedennogo treatment has a positive dynamics as subjective symptoms, and laboratory studies demonstrating the improvement of the functional state of liver energy metabolism and adaptation processes.
Patient SNN., 55 years history No. 944. Diagnosis at admission: ECB. Cholecystectomy in 2005, Chronic biliarsky pancreatitis in the phase of incomplete remission. Complaints at admission: General weakness, fatigue, pain in the epigastric region and around the navel soon after eating, flatulence, constipation. Palpation of the abdomen - mild tenderness in the epigastric region, the projection of the pancreas and in the right hypochondrium. Liver at the edge of the costal arch, painless.
Blood count; white blood cell count is 3.5·109/l, lymphocytes - 20%, neutrophils - 68%, monocytes - 8%, eosinophils - 2. Blood bilirubin - 29 mmol/l, cholesterol - 3.6 mmol/l, alkaline phosphatase - 124 u/l, the MDA level in plasma is 1.16 mmol/l ATP in erythrocytes - 600 µmol/l AMP - 60 µmol/l, the energy charge - 0,82 ed, the LDH activity in lymphocytes - 1025 units and GFDG - 525 units, lactate - 2.9 mmol/l pyruvate - 0,080 mmol/l, which is typical for a deficit of energy metabolism. A course of treatment: mode of motor activity sparing, meals according to the diet №5, internal reception mineral water source Slavyanovskaya", mineral baths (10) electrophoresis of 2.5% solution of succinic acid in the description of the Noah above methodology, 10 sessions of treatment. At discharge from the hospital had no complaints. Palpation tenderness of the abdomen was not determined. The liver is not enlarged. Blood count: leukocytes - 6,2·109/l, lymphocytes - 33%, neutrophils - 59%, monocytes - 4%, eosinophils - 2%. Blood bilirubin is 17.2 µmol/l, cholesterol - 3.6 mmol/l, alkaline phosphatase - 101 u/l, the level of MDA in plasma - 0.84 µmol/l, ATP in erythrocytes - 680 µmol/l AMP - 43 µmol/l, the energy charge - 0,89%, LDH activity in lymphocytes - 1070 units and GFDG - 560 units, lactate - 2.0 mmol/l pyruvate - 0,070 mmol/L. Thus, improving clinical assessment is marked on the background of the improvement of the functional status of the liver and energy metabolism and the state of adaptation. He was discharged with improvement.
Patient SGA 52-year history No. 1543. Diagnosis: ECB. Cholecystectomy in 2003, Chronic gastroduodenitis with stored secretory activity in the phase of incomplete remission. Complaints at admission: General weakness, decreased performance, irritability. Pain whining character in the upper abdomen after 1 hour after eating, heaviness in the right hypochondrium, heartburn, bitter taste in the mouth, belching air, flatulence, constipation change breaks a chair. Blood count: leukocytes - 3,7·109/l, lymphocytes - 18%, neutrophils - 70%, monocytes 8%and eosin is the world of cultural - 2. Blood bilirubin at 18.1 µmol/l, cholesterol - 4.8 mmol/l, alkaline phosphatase - 211 u/l, the level of MDA in plasma - 1,29 mmol/l Detected overall energy deficit: the level of ATP in erythrocytes - 524 μmol/l AMP - 72 µmol/l, the energy charge to 0.08, units of LDH activity in lymphocytes - 1095 units and GFDG - 580 units, lactate is 2.44 mmol/l pyruvate - 0.09 mmol/l treatment - regimen physical activity sparing, meals according to the diet No. 5, the internal intake of the mineral water source Slavyanovskaya", mineral baths (10), electrophoresis of 2.5% solution of succinic acid by the method described above, 12 procedures for the course of treatment. At discharge from the hospital had no complaints, pain abdominal palpation was not determined. The liver was reduced to normal size. As a result of the treatment the patient's condition has improved, disappeared abdominal pain, dyspepsia, became more regular stools, decreased bloating, improved appetite, sleep, became more cheerful, decreased General weakness.
Survey data after treatment: the number of leukocytes - 7,8·109/l, lymphocytes - 23%, neutrophils - 65%, monocytes 7%, and eosinophils - 3%. Bilirubin blood of 13.1 µmol/l, cholesterol - 4.1 mmol/l, alkaline phosphatase - 136 u/l, the MDA level in plasma is 0.86 µmol/l, ATP in erythrocytes - 582 µmol/l AMP - 48 µmol/l, the energy charge - 0,83% the Activity of LDH - unit 1040, a-GPD is - 550 units, lactate - to 1.42 mmol/l pyruvate - 0,049 mmol/l In the treatment of positive dynamics of clinical symptoms and laboratory data (Hematology indicators, test, liver function test, indices of adaptation and energy metabolism).
The method was tested in conditions of Zheleznovodsk clinic - branch of Federal state institution "Pyatigorsk, GNIIT University on two groups of patients - main (20 people) and in the comparison group - control (25 people), treated according to the method of the invention and prototype respectively. Clinical characteristics of patients are shown in table 1.
Clinical characteristics of the main and control groups of patients
|Index||The main group n=20 number %||Control group n=25 number %|
|over 50 years||10-50||12-48|
|Time after surgery||up to 3 years||6-30||12-48|
|more than 5 years||8-40||10-40|
As the data in table 1, the distribution of patients according to the main clinical characteristics in the main and control groups was identical.
We identified a significant impairment of energy metabolism in patients after cholecystectomy. The data of these indicators in comparison with healthy individuals are given in table. 2.
Indicators of energy metabolism in the blood of patients after cholecystectomy and healthy persons
|healthy individuals (n=15)||sick individuals (n=45)||I-II|
|ATP µmol/l||689,87±25,64||472,9 6,16||<0,05|
|SDG, % active.||1071,13±4,51||1246±6,40||<0,05|
|MDA plasma, mmol/l||1,03±0,02||0,98±0,03||>0,05|
Insufficient energy supply significant portion of patients after cholecystectomy leads to the need to consider this fact as in the appointment of the motor mode and the degree of load treatments, and the inclusion of additional medical factors.
Dynamics of clinical manifestations of the disease in the main and control Gruppo reflected in the table. 3.
|Tab the Itza 3|
Dynamics of clinical symptoms and objective data that results from the application of the method of the invention (I) and prototype (II)
|Index||I main group (n=20)||II control group (n=25)|
|the source frequency indicator||positive dynamics||the source frequency indicator||positive dynamics||P|
|Tenderness to palpation of the abdomen||6-30%||5-83,3%||7-28%||3-43%||<0,05|
Are given in table. 3 data show that the positive dynamics of the main manifestations of the disease was more pronounced in the study group compared to control who inoj - this refers to pain and dyspeptic syndrome and normalization of liver size.
According to laboratory studies noted the following changes in the main indicators of the functional state of the liver, lipid peroxidation and energy metabolism in the main and control groups (table 4, 5).
Blood biochemical parameters before and after treatment in the main and control groups of patients
|Index||I main group (n=20) M±m||II control group (n=25) M±m||p|
|before the treatment||after the treatment||before the treatment||after the treatment||I-II|
|Alkaline phosphatase, u/l||123,3±5,0||by 115.7±4,2||of 123.2± and 4.9||121, 1million±4,8||>0,05|
|MDA in plasma, mmol/l||1,03±0,04||0,85±0,03||0,94±0,03||0,91±0,03||<0,05|
Indicators of energy metabolism before and after treatment in the main and control groups of patients
|Index||I main group (n=20)||II control group (n=25)||p|
|before the treatment||after the treatment||before the treatment||after the treatment||I-II|
|ATP µmol/l||473,2±a total of 8.74||524,9±10.30 a.m.||472,6±8,78||484,3±6,86||<0,05|
|Lactate, mmol/l||3,49±of € 0.195||a 3.87±0,558||4,01±0,21||3,9±0,43||>0,05|
The survey results show an improvement of the functional state of the liver, indicators of lipid peroxidation and energy metabolism. When comparing the results of treatment in both groups was observed a marked advantage medical complex using electrophoresis of succinic acid. In contrast to the control group of patients in the study group was significantly decreased levels of bilirubin in the blood and MDA in plasma significantly increased ATP levels and energy charge, decreased levels of AMP and pyruvate.
Thus, patients who underwent cholecystectomy, there is considerable disturbance of the General condition in the form of pain, dyspeptic and astheno-neurotic syndrome, as well as violations of the functional state of the liver and processes of adaptation according to the hematological parameters, lipid peroxidation and energy in the ical exchange.
To increase the effectiveness of rehabilitation treatment after removal of the gall bladder at the stage of sanatorium-resort treatment, along with the ingestion Slavophiles mineralized sulphate-hydrocarbonate calcium-sodium mineral water and mineral baths, recommended the appointment of electrophoresis of 2.5% solution of succinic acid by the developed technique, this helps to reduce the severity of the syndrome of disturbed digestion after surgery, stabilization of peroxide homeostasis and increase the adaptive capacities of the organism, including energy metabolism.
The method of treatment of patients after gallbladder removal, which includes gentle or gently-training regimen physical activity, meals according to the diet №5, ingestion mineralized Slavophiles sulphate-hydrocarbonate sodium-calcium mineral water and holding mineral baths using Slavophiles sulphate-hydrocarbonate sodium-calcium mineral water at a temperature of 36-37°C for 12-15 min, 8-10 treatments on the course of treatment, characterized in that it further carry out electrophoresis of 2.5%aqueous solution of succinic acid in the interscapular area with the cathode at the location of the other strip - anode - area projection of the liver and right poreber is at an amperage of 15 to 25 mA for 15-25 minutes each day, treatment of 10-12 procedures.
FIELD: medicine, surgery.
SUBSTANCE: invention relates to a method for prophylaxis of arising complications in period of post-operation treatment of patients. Method involves carrying out cannulation of umbilical vein in patients. During post-operation period intraportal infusions of ozonized sodium chloride physiological solution is carried out in the dose 200 ml, 2 times per 24 h. The ozone concentration in solution is 3-5 mg/l at the rate of administration 10 ml/min. Immediately before infusion 10 ml of 0.25% novocain solution is administrated by intraportal route. Method provides rapid administration of ozonized solution into the portal system and without development of pain syndrome and adverse responses of body as dyspeptic disorders.
EFFECT: improved method of prophylaxis.
FIELD: pharmaceutical industry.
SUBSTANCE: invention proposes use of 2-amino-7-bromo-4-acetylazo[5,4-b]indol depicted by formula: against hyperbaric and hematic hypoxia and protection of liver against carbon tetrachloride poisoning. Use of this compound reduces concentration of AlAT by a factor of 2.6 and that of AcAT by a factor of 1.67.
EFFECT: increased therapeutic activity.
SUBSTANCE: method involves administering pharmaceutical composition for restoring liver functions, cholesterol metabolism and intestinal biocenosis.
EFFECT: enhanced effectiveness of treatment.
13 cl, 1 tbl
SUBSTANCE: method involves introducing human fetus liver cells suspension containing stem cells, into patient liver and/or in pareneteral way. The suspension is introduced under ultrasonic control in the amount of 200-300 millions of cells under hepatic capsule at a depth of 0.5-1.0 cm. Being intravenously introduced, the dose is equal to 1.0-1.5 billions of cells. When combining both introduction methods, the total dose does not exceed 1.5 billions of cells.
EFFECT: stable restoration of kidney functions.
SUBSTANCE: method involves introducing Detralex at a dose of 500 mg twice a day. No hemorrhages threatening, the grug is introduced in interrupted mode like 30 days receiving the drug and 1 month log pause. Marked gastroenteropathy being the case with hemorrhages threatening, the drug is administered in continuous mode within 2-6 months. Control esopahagoduodenoscopy and endoscopically sclerosing varicose veins of cardia is carried out when indicated. Next, the treatment is continued in interrupted mode. General therapy period is equal to 2-4 years in both groups.
EFFECT: enhanced effectiveness of treatment; no adverse side effects observed; reduced risk of gastrointestinal hemorrhages.
FIELD: chemical-pharmaceutical industry, medicine, pharmacy.
SUBSTANCE: invention relates to a solid medicinal formulation of hepatoprotective effect that comprises combination of flavanolignan with phopholipids as active components and special additive - colloidal silicon dioxide, polyvinylpyrrolidone, trehalose, sodium stearylfumarate, calcium phosphate and/or mannitol. Method for preparing this medicinal formulation involves a wetting step of mixture of phospholipid with colloidal silicon dioxide with small amount of water in the mass ratio about 2:1, respectively, addition of flavanolignan, calcium phosphate and/or mannitol, trehalose followed by wetting the mixture with 15% polyvinylpyrrolidone aqueous solution, wet and dry granulation and powdering dry granulate with sodium stearylfumarate. Agent is prepared in form of capsule preferably. Invention provides simplifying technology and enhancing stability of agent and expands assortment of agents of hepatoprotective effect.
EFFECT: improved and valuable medicinal properties of formulation.
4 cl, 1 tbl
FIELD: medicine, hepatology.
SUBSTANCE: invention proposes a drug for treatment of chronic hepatitis B in the exacerbation stage based on using fumaric acid (tris-2-oxyethylammionium fumarate) triethylamine salt. This salt possesses antioxidant and immunomodulating properties, allows decreasing the level of autoimmune damage of liver cells. Effect of this drug has been studied by indices of intoxication syndrome in patients, decreasing bilirubin content and cytolysis enzymes.
EFFECT: valuable medicinal properties of drug.
FIELD: medicine, pharmaceutical industry, phytotherapy, pharmacy.
SUBSTANCE: invention proposes a hepatoprotective agent showing antioxidant activity, in particular, to using a plant dropwort (Filipendula ulmaria (L.) Maxim.) above-ground part as a hepatoprotective agent possessing the antioxidant activity. Method for preparing a hepatoprotective agent possessing the antioxidant activity involves extraction of vegetable raw with ethanol in percolator devices battery wherein dropwort (Filipendula ulmaria (L.) Maxim.) above-ground part is subjected for extraction under definite conditions. Extract possessing the hepatoprotective effect prepared by above describes method possesses the enhanced antioxidant activity.
EFFECT: valuable medicinal property of agent, improved prepared method.
3 cl, 5 tbl, 4 ex
FIELD: medicine, hepatology.
SUBSTANCE: invention proposes a preparation containing spotted milk thistle fruits extract and field artichoke leaves extract or pumpkin seeds extract, and normophlora active microorganisms sorbed on a carrier. The preparation comprises lactulose or lactose, or lactite as an agent stimulating multiplication of microorganisms. Components of the preparation are placed into two capsules wherein one capsule comprises plant extracts possessing the hepatoprotective effect, and another capsule comprises intestine normophlora microorganisms and agent stimulating multiplication of microorganisms. Invention provides enhanced effectiveness in treatment of diseases associated with liver damage, accelerating regeneration and recovering functional activity of hepatocytes. Invention can be used in treatment of liver and hepatobiliary system diseases.
EFFECT: valuable properties and enhanced effectiveness of preparation.
6 cl, 4 tbl, 8 ex
SUBSTANCE: it has been suggested the method for introducing a preparation in efficient dosage being either a substance or preparation prepared according to homeopathic technique or biologically active additive that contains a substance isolated out of hepatic cells being slightly hydrophobic, water-soluble, negatively charged at alkaline pH, at molecular weight ranged 500-15000 Da that enables to decrease tissue-specifically the ratio of phosphorylated adenosine diphosphate against the quantity of atomic oxygen spent by highly energized mitochondria in the course of oxidizing phosphorylation. The suggested method and preparation enable to treat efficiently astheno-depressive state and, also, increases the efficiency of complex therapy of pulmonary and intestinal diseases.
EFFECT: higher efficiency of therapy.
16 cl, 21 ex
FIELD: medicine, medicinal equipment.
SUBSTANCE: the present innovation deals with devices and methods for perosseous and/or intraosseous injection of medicinal substances. The kit for delivering electric current and/or voltage to a part of skin and/or for perosseous or intraosseous injection of substances contains a cutaneous applicator that contains a power pack and, at least, two electrodes being electrically connected with the power pack and indicated for electric connection with a patient's part of skin and, at least, one separator for keeping electroconductive flowing medium. The latter is indicated to be applied onto, at lest, one electrode and/or locally applied onto a patient's part of skin. In one variant, a thin elastic cutaneous applicator has got a thin elastic power pack and thin chamber that contains electroconductive flowing medium/composition, in which a thin chamber is located in, at least, one mentioned negative electrode and, at least, on one positive electrode. The innovation enables to increase the universality of cutaneous applicators due to introducing any desired number of substances in any desired dosages.
EFFECT: higher efficiency.
85 cl, 6 dwg
SUBSTANCE: method involves applying therapy course containing iodine-bromine baths and vaginal irrigations given every other day. Electrophoresis is administered in days free of baths and irrigations after 2 adaptation days with silt mud enriched in hydrogen sulfide water containing hydrogen sulfide in concentration of 350 mg/l. The treatment is applied to hypogastric and lumbosacral region at the level of L4-S2 vertebrae. Electric current intensity is equal to 0.05-0.1 MA/cm2 during 20 min. The total treatment course is 8 balneo- and physioprocedures long.
EFFECT: reduced peritoneal commissure process intensity; normalized vegetative nervous system and ovarian functions; improved cellular and humoral immunity; increased female fertility.
SUBSTANCE: method involves placing three circular electrodes of different area so that the smaller two are placed on orbital and upper eyelids region skin when eyes are closed. They are connected with split wire to an electrode of greater area that is placed in cervico-occipital region of patient head. Injured regions electrophoresis is carried out with 1.5% Neuromidine solution according to ophthalmo-occipital method placing patient in dorsal position. Current is supplied to light pricking sensation under the electrodes. Given current intensity is controlled over the treatment time. Procedure duration is 15-20 min and treatment course is 15 daily sessions long.
EFFECT: enhanced effectiveness in treating defective neuromuscular eyeball synapses and nuclear structures of oculomotor nerves.
SUBSTANCE: in pre-surgical period one should introduce Collagenase CC due to electrophoresis onto anterior abdominal wall in area of adhesive process. After abdominal cavitary sanitation and the main stages of operation it is necessary to introduce 500 mg Collagenase CC 250 U dissolved in 100 ml physiological solution into area of deserosed intestine. The innovation prevents the relapse of adhesions.
EFFECT: higher efficiency of therapy.
2 ex, 1 tbl
FIELD: medical equipment.
SUBSTANCE: therapeutic needle electrode, used for through-skin galvanic therapy of tumors, can be used for visualization due to methods of forming image; it is made of titanium. Electrode has coating made of platinum; coating is applied by method condensation from vapor phase. Excluding end area of needle, electrode is covered with electrical insulating polymer.
EFFECT: reduced costs; higher strength of electrode; prevention of traumatism of tissues.
15 cl, 1 tbl, 1 ex
SUBSTANCE: method involves making local 5% aminocaproic acid injection into periocular tissues in the amount of 1.0 ml. Then, bath electrophoresis is carried out 1-2 h later in hyphaema cases. Endonasal electrophoresis is applied in hemophthalm cases and eye fundus hemorrhages with proteolytic enzymes like 0.2% trypsin and chemotrypsin solution for 15-20 min with current intensity of 1.5 mA. Intravenous infusion of 100 ml of 0.03% sodium hypochlorate solution is carried out once or twice a day with the number of injections equal to 2-3 in hyphaema cases and 3-5 injections in hemophthalm and hemorrhages cases.
EFFECT: high accuracy of early stage diagnosis.
SUBSTANCE: method comprises sparing or sparing and training regimen of motion activity, special diet (number 5), oral administration of low-mineralized and low-carbonized calcium-sodium sulfate-hydrocarbonate mineral water and performance of low-carbonized calcium-sodium sulfate-hydrocarbonate mineral baths. Additionally, electrophoresis with 2% succinic acid solution is effected for 15-20 min on trigeminal nerve innervation region in the form of half-mask. Treatment of the left and right halves of the face are alternated. Treatment course comprises 12 procedures.
EFFECT: improved energetic exchange and adaptation processes.
1 tbl, 2 ex
SUBSTANCE: device has copper activator and sealing cuff. The sealing cuff, restrictor and cap sealing activator end face are pressed against the activator end face.
EFFECT: strengthening antitumor activity of the organ.
SUBSTANCE: method involves carrying out single intracanal electrophoresis with 50% Dimexid solution during 4-6 min from anode before setting permanent filling into dental canals. Then the canals are temporally filled with professional Metrogil gel for 7-10 days.
EFFECT: enhanced effectiveness of treatment; improved bactericidal and anti-inflammatory results.
SUBSTANCE: method involves introducing medical preparations in retrobulbar way during 10 days 4-6 times a day with 2-4 h long pauses through an orbital photoelectrode-catheter. Laserophoresis and direct laser stimulation are applied after the first retrobulbar introduction of the preparations, giving one session every day using therapeutic ophthalmologic laser device operating on wavelength equal to 0.633±0.003 mcm during 8-10 min in combination with drug electrophoresis introduced in retrobulbar way from positive pole and optic nerve and retina electrostimulation carried out with a device during 10-12 min one session a day. Electrostimulation is carried out in package mode with rectangular pulses having amplitude of 5-1000 mcA, pulsation frequency of 0.5-100 Hz, pulse duration of 1-500 ms. The pulses are collected in packages having 2-75 pulses in a pack with pause duration between packages equal to 0.5-60 s. The number of packages in one series is equal to 5-300. The number of series is 3-30 and pause duration between series is equal to 5-150 s. Laserophoresis with laser stimulation and electrophoresis with electrostimulation are applied in arbitrary sequence or given in single stage.
EFFECT: created required therapeutic concentration of medical preparations directly in retina and optic nerve; increased metabolism intensity; stimulated regeneration processes.
SUBSTANCE: method involves administering peloidotherapy as applications over lower extremities with sulfide mud temperature of 37-38°C during 10-15 min in 10 procedures long course alternating with carbonic-acid/hydrogen-sulfide water baths taken at 36°C during 10-15 min. The total treatment course is 10 procedures long.
EFFECT: reduced glycemia profile level; reduced lipid metabolism indices; improved regional blood circulation.