FIELD: medicine, in particular biologically active mud preparation useful in therapy as applications.
SUBSTANCE: claimed peloid applicator contains mud paste from peat peloids with deterioration ratio of 50 % or more and mineral sodium hydrocarbonate water in ratio of 3:1 and additionally it contains dihydroquercetine in amount of 39-41 g per 1 kg of paste.
EFFECT: applicator with sufficient skin penetration and high antioxidant properties.
The invention relates to medicine, namely to create biologically activated mud drugs, and can be used in physiotherapy as applications.
The prior art mud preparations from native mud in which to increase the biological activity impose additional biologically active substances. For example, the famous mud preparation of sulfide mud with addition of whey in the amount of 155 ml per 1 kg of air-dry dirt and 395 ml of tap water (EN p, AC 35/10).
The technology of manufacturing of this drug allows you to use it only at home.
There is a method to increase the biological activity of aqueous fraction of mud, according to which the aqueous fraction is divided into two equal parts, the first portion is irradiated with UV rays from a distance of 25-30 mm for 10-12 minutes, and the second add ascorbic acid in a concentration of 50-60 mg per 1 l of aqueous extract, after which the two portions are mixed (EN p, A61K 35/02).
This method allows to increase the output of ascorbic acid in 3-4 times, and total protein by 25%. The liquid state of this drug would narrow its application. So, for the treatment of relevant diseases it can be used during electrophoresis, acceptance bathrooms procedures, excluding the application. In addition, t is hnology preparation of this drug complex.
The closest technical solution to the claimed is peloid applicator peat mud paste "Chinska from peat peloids with the degree of decomposition of 50% or more and mineral sodium bicarbonate water "Khabarovsk 1 in the ratio 3:1 obtained according to the method according to p, A61K 7/48, A61K 35/10.
Balanced natural complexes of biologically active and nutrients peat peloids and mineral water "Khabarovsk 1" define a sufficiently high biological value pasta. However, the production of pasta by mixing peat peloids and alkaline mineral water still does not allow to obtain a sufficiently high concentrations of amino acids, although their composition in the mixing increases to 19 items. This non-essential amino acids: arginine, cysteine, tyrosine, alanine, serine, Proline, glycine, asparagine, aspartic acid, glutamine, glutamic acid, essential acids: histidine, valine, isoleucine, leucine, lysine, methionine, threonine, phenylalanine.
The use of this drug with such a concentration of basic amino acids as self-healing agent does not bring the desired effect because of its lack of permeability through the skin. In addition, the drug and the above-mentioned analogues have insignificant the mi antioxidant properties.
The technical result of this technical solution is the creation of peloid applicator with sufficient permeability of the skin and elevated natural antioxidant properties.
The technical result is achieved by the fact that peloid applicator containing peat mud paste "Chinska from peat peloids with the degree of decomposition of 50% or more and mineral sodium bicarbonate water "Khabarovsk 1 in the ratio 3:1, while further comprises dihydroquercetin with concentration 39-41 lhs for 1 kg of paste.
Included in the applicator dihydroquercetin in the claimed amount in the process of mixing components in connection with mineral alkaline water enhances cationic exchange its homogeneous mass, which provides sufficient permeability of the skin to Deposit in the body of nutrients and biologically active substances, even in small concentrations, and enhanced therapeutic effects on the human body a wide range of natural vitamins: B1In2In3In5In6In9B12. In addition, dihydroquercetin, as a synergist with vitamin C, stimulates the immune system of the human body, acting as immunocorrector, i.e. usalive is its natural antioxidant properties.
The applicator is prepared as follows.
Previously, mineral water "Khabarovsk 1" enter dihydroquercetin based 39-41 lhs 1 kg pasta "Chinska and stirred until complete dissolution. Preparation of peat and further preparation of the applicator conduct similar to cooking pasta "Chinska" according to p. No. 2256438.
Because of dihydroquercetin is a preservative, in the manufacture of the drug there is no need for preservatives as DMDM (a derivative of formaldehyde), affecting the skin of the person. Ready applicator Packed in sealed plastic bags suitable for packing food products with a capacity of 0.5 to 5 kg, which is placed in a transport package weight 20, 30 and 50 kg and is sent to the finished goods warehouse, where it is left for 30 days. 7 days before sending to the consumer, generate random samples for sanitary-microbiological control for compliance with the quality indicators new project pharmacopoeial articles.
Peloid applicator "Thelma" is a homogeneous plastic mass and has a high aromaticity, characterizing the degree of permeability.
|Granular composition of carbon in liquid concentrated phase of peloid applicator "Thelma".|
|Designation||The content of the structural fragments of qx,% Rel.||The range of chemical shifts (CS), ppm, assignment signals|
|With=O||4,4||220-186||Carbon atoms karbonilnyh groups|
|COhin||9,8||186-180||Carbon atoms quinoid groups|
|(O)HE, C(O)OR||15,2||185-168||The carbon atoms, carboxyl, hard-ester groups|
|Cap-O||17,9||164-140||Aromatic carbon atoms connected with oxygen atoms|
|WitharC,H||38,4||140-103||C - and N - substituted aromatic carbon atoms|
|Clcarbohydrates||5,1||103-96||Anomeric atoms plastoglobuli|
|3,6||93-80||The carbon atoms in α-O-4 and β-O-4-linkages "lignin" components|
|Cho, CH2O||5,5||80-58||The carbon atoms-CH-O CH-N-fragments|
|CH3About||0||58-54||Carbon atoms metaxylene groups|
|WithAla||0,1||54-20||The carbon atoms of alkyl fragments|
|The degree of aromaticity (ƒa)||57||164-103||ƒa=Iap/I total|
Declare peloid applicator "Thelma", providing optimum permeability of the skin, and also has an antioxidant effect, will find, in the author's opinion, wide application.
Peloid applicator containing peat mud paste "Chinska from peat peloids with the degree of decomposition of 50% or more and mineral sodium bicarbonate water "Khabarovsk 1 in the ratio 3:1, characterized in that it further comprises dihydroquercetin with concentration 39-41 lhs for 1 kg of paste.
FIELD: medical engineering.
SUBSTANCE: system is selectable from a group having implant, intrauterine system, intracervical system or intravaginal system having core and membrane. The core has at least one therapeutic agent and at least the first and the second part. At least one separating membrane is available between the first and the second part. The core and membrane are manufactured from elastomer composition like poly(dimethylsiloxane), siloxane -based elastomer having 3,3,3-trifluoropropyl groups attached to Si atoms of siloxane links, or elastomer composition having poly(alkyleneoxide) groups available as alcoxi- terminal engrafting or units connected to polysiloxane links with carbonic silicon bonds, or as mixture of given forms and combination at least of two from them. The core and membrane have identical or different elastomer compositions.
EFFECT: enabled at least two agents release at the same time at preset rates; excluded harmful action in system damage cases.
22 cl, 14 dwg
FIELD: medical engineering.
SUBSTANCE: device has casing structure and at least one capsule containing pharmaceutical composition. The capsule has at least the first and the second end. The casing structure has at least two stopping members. Each stopping member has at least the first and the second end. The first one has surface fitted for converting and coating one of at least the first and the second capsule end. Diameter of at least one stopping member varies with its length between the first and the second end. The capsule is mounted between said the mentioned at least two stopping members. The casing structure is produced by molding under pressure. The capsule is produced by molding under pressure on the casing structure at the next stage.
EFFECT: excluded capsule displacement on the casing; excluded capsule separation from the case; simplified system removal from body cavity.
11 cl, 30 dwg
SUBSTANCE: method involves applying sacral neuromodulation treatment including search and puncture sacral orifices using injection needles. Right and left sacral apertures are punctured at S3 level with alloplant solution being introduced into them. The quantity of the alloplant solution injected is equal to 2 ml in each orifice. The total treatment course is 3 injections long with one injection introduced every З days.
EFFECT: wider gamma of sacral neuromodulation methods; avoided adverse side effects; accelerated 10 days long treatment course.
4 cl, 12 tbl
SUBSTANCE: method involves administering triple injections of medicament mixture composed of Lidase 32 units, Anicaine 4ml, Dexamethazon 4 mg, Alflutop 1 ml, into Hoff fat pad.
EFFECT: reduced pain and knee joint edema manifestations; increased joint range of motions.
SUBSTANCE: method involves beginning disinvagination with mask narcosis by pumping air into large intestine under X-ray control. The invaginate remaining unstretched, the air is discharged from the intestine by massaging abdomen along the large intestine and pressing abdomen flanks. Next to it, air is pumped into the large intestine and invaginate stretching is carried out with an additional coercion by squeezing invaginated head out towards the neck part. No success being achieved, the procedure is repeated with mask narcosis to eight times. The invaginate remaining unstretched, endotracheal narcosis is given to the patient and myorelaxant drug of transitory action is introduced. Air volume introduced into the intestine is increased. The invaginate-stretching procedure is repeated with endotracheal narcosis to five times.
EFFECT: enhanced effectiveness of treatment.
SUBSTANCE: invention provides a chemotherapy method that can be used in treatment of patients with widespread abdominal tumors. When performing laparotomy, sub-peritoneal infiltration with autoblood solution containing chemical agent is effected on zones of tumor infiltrates (supraperitoneal paraaortic tissue) and root of mesentery region.
EFFECT: expanded tumor treatment possibilities.
FIELD: medicine, arthrology.
SUBSTANCE: the present innovation deals with treating arthritis of different etiology. For this purpose one should introduce medicinal preparation into articular cavity and immediately after introduction one should periodically change spatial articular position at the interval of 20-30 min. The present innovation provides efficient and safe treatment of arthritis due to steady distribution of medicinal substance along the whole area of articular surface.
EFFECT: higher efficiency of therapy.
1 cl, 2 ex
FIELD: medicine, in particular, rectal dosed transportation of medicinal drugs into straight intestine.
SUBSTANCE: dosing apparatus has casing adapted for introduction into hollow organ and made in the form of continuous rod. Cavities for treating ointments on cylindrical outer part of rod are formed as slots. Rear end of rod has reduced diameter in comparison with maximal diameter of rod. Guiding pipe loosely put onto said end has outer diameter exceeding maximal diameter of casing. Figures are applied in equally spaced relation along length of pipe. Flexible cord with round restricting member is fixed at rear end of rod.
EFFECT: increased efficiency in transporting of high-density medicinal drugs, in particular, treating ointments, immediately to point of application.
2 cl, 2 dwg
FIELD: medical procedures.
SUBSTANCE: patients preliminarily undergo endoscopic papillo-sphincterotomy, whereupon stone in common bile duct is dissolved and removed by way of supplying stone-dissolving therapeutic mixture, in particular 1:1 solution of diethyl ether in olive oil, directly to bile stone. Therapeutic mixture creates, in the lumen of bile duct, hydrostatic pressure 200 mm water head. More specifically, 120 ml of therapeutic mixture is supplied during one day at a rate of 10 drops/min, while performing 5 to 16 daily sessions of stone-dissolving therapy.
EFFECT: increased efficiency in removal of sparingly soluble stones in common bile duct.
FIELD: medicine, medicinal parasitology.
SUBSTANCE: the present innovation deals with affecting the helminthes with curative mixture made out of eucalyptus leaf at addition of eucalyptus essential oil. Curative mixture at the quantity of 1 l at 40-42 C should be daily introduced into patient's rectum with enemas for 5-7 d at intestinal keeping for 15-20 min. Before introducing the curative mixture it is necessary to apply purifying enema. The method suggested provides removal of different types of helminthes at excluding toxic action upon human body.
EFFECT: higher efficiency of helminthic removal.
FIELD: chemical-and-pharmaceutical industry, food processing and cosmetic industry.
SUBSTANCE: claimed agent represents extract obtained by treatment of natural Baltic amber with 40-96 % and further 88-96 % ethanol and contains succinic acid, salts thereof, amber oil, iodol, carbon-oxygen-hydrogen-containing substances, 40-96 % ethanol in specific component ratio. Agent may be performed in form of solution, powder or tablet. Method for production of said agent includes sequential washing of natural Baltic amber with water, then with salt aqueous solution, followed by double extraction with ethanol.
EFFECT: agent with wide spectrum of therapeutic action.
3 cl, 6 ex
FIELD: medicine, in particular therapeutic stomatology.
SUBSTANCE: claimed method includes using of Bezornyl ointment, wherein in generalized paradontitis of mild case ointment is applied on region of marginal parodontium and dentogingival papillae in dose of 0.005-0.1 g under dressing for 2 hours, and in generalized paradontitis of medium and severe case ointment is introduced directly in each parodontal pocket in dose of 0.005 g. Treatment course is 2-5 procedures with interval of 1 day.
EFFECT: effective preparation for topical application without administration of antibiotics and complex preparations.
2 ex, 1 tbl
SUBSTANCE: method involves carrying out vacuum massage of prostate with an apparatus. Tampons with 40-45°C hot sulfide mud taken from Sucsun pond are additionally rectally introduced for 20-30 min. The total treatment course is 8-10 procedures long. Daily microenemas are prescribed with mineral water at 36°C in a 10 procedures long course.
EFFECT: enhanced effectiveness of treatment.
FIELD: medicine, pharmacy.
SUBSTANCE: invention relates to inflammatory agents. Invention proposes the ointment that comprises liquid potassium humate, birch tar, sodium silicate, vaseline wherein the potassium liquid humate comprises the humic substances in the amount 4.5 g/l, not less. Invention provides enhancing storage time, stability, high effectiveness and the broad spectrum of effect.
EFFECT: valuable medicinal and pharmaceutical properties of ointment.
2 cl, 6 ex
FIELD: pharmaceutical industry, in particular production of moor preparation.
SUBSTANCE: claimed method includes extraction of moor raw material such as peaty piloids with decomposition rate of 50 % or more, decontamination, homogenization by agitation in mortar-mixer with addition of mineral sodium hydrocarbonate water under specific conditions followed by pulping through screen to produce product with shearing resistance of 1500-4000 din/cm3 and conserving agent addition. As conserving agent hydantoin in specific ratio is used. Then product is pre-packed in sealed containers and conditioned in stock for ageing.
EFFECT: peaty moor dough with increased biological value, high penetrability, improved nutrient and healing effects.
FIELD: method for production of bioproducts from native divot peloid with high biological activity.
SUBSTANCE: claimed method includes extraction of fine dispersed divot peloid having plant residual decomposition ratio of 50 % or more with sodium hydrocarbonate-containing water at elevated temperature under intensive agitation to produce homogeneous suspension followed by separation under certain conditions.
EFFECT: ecologically pure concentrated peloid extract with high biological activity.
FIELD: medicine, phthisiology.
SUBSTANCE: in early period the preparation "Yantar-antitoks" is used in the dose 0.5 g, 3 times per a day for one month in addition to the conventional antituberculosis therapy. Invention promotes to elimination of symptoms associated with the total intoxication, resorption of focus-infiltration changes, elimination of destructions and ceasing secretion of microorganisms for shorter periods. Invention can be used in treatment of pulmonary tuberculosis.
EFFECT: improved method for treatment.
4 tbl, 1 ex
FIELD: medicine, pharmacology.
SUBSTANCE: invention relates to a medicinal agent used in treatment of warts. Proposed agent contains an active compound chosen from isopropyl laurate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, ethyl myristate, propyl myristate, butyl myristate and/or ethyl oleate and at least a mixture containing (-)-epicatechol, (-)-epicatechol gallate, (-)-epigallocatechol, (-)-epigallocatechol gallate, (+)-gallocatechol and (-)-gallocatechol gallate possessing the enhanced effectiveness.
EFFECT: valuable medicinal properties of drug.
7 cl, 2 ex