Biologically active agent of wide action spectrum and method for production thereof

FIELD: chemical-and-pharmaceutical industry, food processing and cosmetic industry.

SUBSTANCE: claimed agent represents extract obtained by treatment of natural Baltic amber with 40-96 % and further 88-96 % ethanol and contains succinic acid, salts thereof, amber oil, iodol, carbon-oxygen-hydrogen-containing substances, 40-96 % ethanol in specific component ratio. Agent may be performed in form of solution, powder or tablet. Method for production of said agent includes sequential washing of natural Baltic amber with water, then with salt aqueous solution, followed by double extraction with ethanol.

EFFECT: agent with wide spectrum of therapeutic action.

3 cl, 6 ex

 

The invention relates to pharmaceutical industry and can be used in medical, cosmetic and food industries based on natural Baltic amber.

Known biologically active food supplements containing the basis of succinic acid or its salts obtained, usually by chemical means (patent N2035880, the application N97121485).

Succinic acid under physiological conditions has the form anion (succinate), the term "treatment" is used as a synonym of the term "succinic acid".

Succinic acid can be found in brown coal, resins, amber, fruits, vegetables, plasma human blood.

Succinic acid and its salts (succinate) possess adaptogenic ability and have antigipoksicheskoe, anti-stress and neurotropic action, normalizes energy and plastic metabolism and General physiological condition of the body, enhances the biochemical and physiological recovery processes in pathology and intensive physical activity.

Unlike used amber tinctures, the invention allows better use available in amber connection, which identified more than 40, to improve organoleptic characteristics.

The present invention is to obtain funds from a wide range of actions on the basis of p is arodnogo Baltic amber.

The problem is solved by a group of inventions.

The proposed biologically active agent, broad-spectrum, representing the extract obtained by processing natural Baltic amber ethyl alcohol 40-96% and then 88-96%, succinic acid, salts of succinic acid, succinic oil, idol, carbon-oxygen-hydrogen compounds succinate (over 40), ethyl alcohol 40-96% in the following ratio of ingredients, wt.%:

succinic acidof 0.001 to 1.0
salt of succinic acidof 0.001 to 1.0
amber oil0,001-0,3
idol0,001-0,1
carbon-oxygen-hydrogen
connection of succinite (over 40)of 0.001 to 2.0
ethyl alcohol 40-96%rest

The tool may be made in the form of a solution, powder, tablets.

A method of obtaining biologically active funds a broad spectrum of action, namely, that natural Baltic amber sequentially washed first with water at a temperature of 55-60°With, then salt aqueous 20% solution, then the extraction is carried out with ethyl alcohol 40-96% when the ratio of amber and alcohol is t 1:1 to 1:10, respectively, within 1 to 90 days, and separating the extract, then re-extracted with ethyl alcohol 88-96% within 3 to 10 days, the extract is separated, then the extracts pooled.

The tool is called "Amber balm".

The invention is illustrated by the following example.

Take natural Baltic amber of any shape, texture, transparency and color, and can also be used in waste during the processing of natural amber, especially consisting of the oxidized surface of amber containing up to 8% succinic acid. You cannot use "immature" amber (age less than 35 million years), such as "dig" fields of Australia, New Zealand and Oceania, Africa, Central and South America that do not contain succinic acid. Unlike the Baltic amber kopali dissolved in ether. You should also not use the amber pressed, as it is the product of the processing of amber flour at high temperature and pressure. If the surface of pressed amber strongly rubbed with a cloth soaked in ether, then it becomes sticky unlike natural amber. In Presolana amber can be observed under a magnifying glass of the flow structure, the balls of the dense core mass, small clumps of dye. Imitation amber of polymers can be easily determined by applying to a surface heated to a red needle and unpleasant chemical Zap the ha, while amber outstanding natural smell of tar.

Prepared for the production of amber should be washed in hot water at 55-60°C by continuous stirring and again wash in salted water 20% solution, rinsed with water and dried. Prepared amber is used both in original form and in the form of ground to amber flour by Bay of their water-alcohol liquid strength from 40% to 96% in a ratio of from 1:1 to 1:10 and infusion for 1 to 90 days with daily stirring and subsequent discharge of the blended liquors in the tank.

For the secondary infusion amber use ethyl alcohol of the highest cleaning strength from 88% to 96% in the ratio of 1:3 within 3-10 days with periodic stirring. Extracts merge in blended Chan, and the secondary infusion is poured in the amount of 80%, and the remaining 20% add after analysis of the blend are in compliance with required parameters. The blend is mixed and sent to the filtering that is performed on a filter press using as filter material filter brand cardboard "e-coat-1P" or "T" and other brands. The average speed of filtering BAD 45-65 gave/h·m2. Included in the means ingredients are used at the following content in kg per 1000 gave the finished product: succinic acid is 0.01 to 10.0; salts of succinic acid is from 0.01 to 10.0; amber oil is 0.01 to 3.0; antiseptic idol 0,1-1,0; other carbon-cisliano-hydrogen compounds succinite from 0.01 to 20.0; ethyl alcohol of the highest purification and drinking water corrected by calculation on the fortress from 40% to 96% of the rest.

The tool has a light brown color, slightly burning taste of pine resin and a subtle milky tint in the reduction of the fortress below 88%.

The present invention allows to obtain a biologically active agent with a broad spectrum of action.

The tool has a wide range of medical action: stimulates the nervous system, improves the function of the kidneys, intestines, liver, used as antistress, anti-inflammatory and anti-toxic agent. Improves the intracellular metabolism, it contributes to the overall improvement of the body, slowing the aging process, regulate the nutrition of the heart muscle, and enhances the action of other medicines.

Especially with high efficiency, it saves you from mastitis, cysts, fibroids and infertility. Impact tools for many types of tumors, including malignant, is associated with the inhibition of abnormal cell division allowing the tumor turns into a cluster of dead cells, which gradually dissolve. In diseases of the joints he restores local krooo the treatment, allowing output of salt.

The tool has a rejuvenating effect, finds himself in the body of those areas that need it. It can be used as in the form of solutions, and in the form of powders or tablets.

Remedy during pregnancy facilitates hormonal changes in the body of the mother, helps to meet the increased needs of the body stores of energy, supports the activity of the immune system, prevents abortion lowers the risk of various complications. The fetus is developing in optimal conditions, with a good supply of oxygen and nutrients, and fortified the placental barrier prevents penetration to the fruit of various toxins, viruses and bacteria. This significantly reduces the risk of a birth of the sick child, the birth process is noticeably shorter and easier. In the postpartum period, he promotes rapid recovery of the parent body and increases the amount of milk. A small dose of funds in the form of food additives contribute to the formation of persistent immunity, improve the health of the child and increases the degree of preparedness for the future.

The tool is capable of preventing dangerous for the body lipid oxidation for a few days to recover memory and physical rabotosposobnom the , to optimize (in moderation abilities of the body) his regular mechanisms and metabolic processes. This retreat "senile disease, normal sleep, eliminated the side effects of medication. To supply the heart muscle is more efficient to combine glucose with the tool.

The tool did a good job in the fight against abortion, accompanying cancer and their treatment with chemotherapy and radiotherapy, as well as at a poisoning of the body by the breakdown products of the tumor.

The tool can be used as supplements to all types of vodka, tinctures, balms, beer and other beverages in liquor industry, as it is largely neutralizes the toxic effects of alcohol.

Specific examples of the application of funds

Example 1.

Prepared Baltic amber natural form is filled with 40% alcohol (vodka) at a ratio of from 1:1 to 1:4 and extracted 90 days at a temperature of 18-20°C. Mixed 1 time per week. The resulting milky white solution is drained, filtered. It has a natural succinic acid and salts of succinic acid. It can be used both in solution and in the form of powders and tablets. The most appropriate application in the form of tablets and powders during pregnancy, when the deseases mastitis, cysts, fibroids and infertility.

Example 2.

Prepared Baltic amber is crushed to a fraction of 0.5 mm and pour a 40% alcohol (vodka) at a ratio of from 1:1 to 1:4 and insist 45 days at a temperature of 18-20°C. Mixed 2 times a week. The resulting solution was used as in example 1.

Example 3.

Prepared Baltic amber natural form is filled with 70% alcohol at a ratio of from 1:1 to 1:4 and insist 30 days at a temperature of 18-20°C. Mixed 1 every 3 days. The resulting solution was faint yellowish tint blends, filtered. It has a natural succinic acid, salts of succinic acid, succinic oil. It can be used both in solution and in the form of powders and tablets. Wide application of this tool has shown to restore the memory and physical performance, in the fight against abortion, as well as at a poisoning of the body by the breakdown products of the tumor.

Example 4.

Prepared Baltic amber is crushed to a fraction of 0.5 mm, and fill in 70% alcohol at a ratio of from 1:1 to 1:4, and insist 20 days at a temperature of 18-20°C. Mixed 1 every 2 days. The resulting solution was used as in example 3.

Example 5.

Prepared Baltic amber natural form is filled 95-96% alcohol. Infuse for 15 days at a temperature of 18-20°C. PE amerivest daily. The resulting solution was yellow in color with a full complement dissolved in alcohol substances fused, filtered. It can be used both in solution and in the form of powders and tablets. Wide application in the form of supplements for all types of vodka, tinctures, balms, beer and other beverages in liquor industry, largely neutralizes the toxic effects of alcohol. In the form of powder and tablets in wide use can be in the treatment of hepatitis and cancer.

Example 6.

Prepared Baltic amber is crushed to a fraction of 0.5 mm and filled with 95-96% ethanol, heated to 50°C for 30 minutes with stirring. Infuse for 1 day. The resulting solution was used as in example 5.

1. Biologically active agent, broad-spectrum, characterized by the fact that it is an extract obtained by processing natural Baltic amber ethyl alcohol 40-96% and then 88-96%, and succinic acid, salts of succinic acid, succinic oil, idol, carbon-oxygen-hydrogen compounds succinate (over 40), ethyl alcohol 40-96% in the following ratio of ingredients, wt.%:

succinic acid0,001 -1,0
salt of succinic acid of 0.001 to 1.0
amber oil0,001-0,3
idol0,001-0,1
carbon-oxygen-hydrogen
connection of succinite (over 40)of 0.001 to 2.0
ethyl alcohol 40-96%rest

2. The tool according to claim 1, which can be made in the form of a solution, powder, tablets.

3. The method of obtaining biologically active funds a broad spectrum of action, characterized by the fact that natural Baltic amber sequentially washed first with water at a temperature of 55-60°With, then salt aqueous 20% solution, then the extraction is carried out with ethyl alcohol 40-96% when the ratio of amber and alcohol from 1:1 to 1:10, respectively, within 1 to 90 days, and separating the extract is then extracted repeatedly with ethyl alcohol 88-96% within 3 to 10 days, the extract is separated, then the extracts are combined and add water to the fortress 40-96%.



 

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