Method for treating patients for glaucoma
SUBSTANCE: method involves applying gel Pantonic over mucous membrane of nasal passages and over superior cervical sympathetic nodes. Each of four fields is sequentially exposed to ultrasonic frequency current action. Action power is 1-2 kV. Action time is equal to 3-4 min.
EFFECT: improved optic nerves excitability and conductivity.
The invention relates to physical therapy and ophthalmology, and is intended for the treatment of glaucoma including in the early postoperative period.
Primary glaucoma is chronic nonspecific respiratory disease characterized by continuous or periodic increase in IOP, the development of specific atrophy of the optic nerve (glaucoma excavation), in connection with development of atrophy - progressive decline in the function of peripheral vision narrowing of the field of view). Currently, most researchers believe glaucoma multifactorial disease in which the result of increased intraocular pressure (IOP) above the tolerance level is infringement of a bundle of nerve fibers in the deformed lattice membrane develops diffuse ischemia and hypoxia in the optic nerve head. Despite the fact that the circulation in the internal structures of the eye are relatively Autonomous and has the ability to autoregulation development of primary glaucoma is caused by changes in the vascular system and of CSF dynamics eyes, on the background of chronic somatic pathology. Therefore, the glaucoma treatment should be complex, aimed not only at reducing intraocular pressure, but also on the activation of the arterial link, improve the trophic and metabolic processes in the nervous ledah of the retina.
The known method of applying darsonvalization region of the orbit in the complex treatment of glaucoma, which use pulsed alternating current of high frequency (110 kHz), high voltage (20 kV) and low power (0.2 mA) (I.N. Sosin and other "Physical therapy of eye diseases, Simferopol, 1998, str).
The method of providing distraction, reflex analgesic effect, improves trophic through increased blood flow, but does not cause a pronounced reduction of intraocular pressure, due to the lack of stimulation of the venous and lymphatic outflow. Selected operational parameters provide for the creation of the spark discharges that affect the eye area, which creates some discomfort of the procedure.
The functionality of the method is limited, as it is used primarily on the testimony of neurological manifestations. In addition, darsonvalization contraindicated in cardiovascular disease, cerebrovascular disease, hypertensive disease, which often features in patients with glaucoma.
Closest to the present invention is a method for the treatment of patients with glaucoma, including the effects on the reflex zones currents supersonic frequency (U.S. Pat. Of the Russian Federation No. 2085157, class a 61 F 9/00, 1993).
In the known method using currents supersonic frequency power is awn up to 3 watts for 15 minutes, the treatment duration 3-5 sessions.
The disadvantages of the method are: high dose rate, which does not allow to use this method in the early postoperative period because of the potential risk of haemorrhagic complications; local impact only on the eye area without considering the etiopathogenetic mechanisms of development of glaucoma with the interest of the Central structures of the brain.
In addition, prolonged exposure to electric current for 15 min for one procedure may lead to a paradoxical reaction and subsequent deeper damage to the nervous apparatus of the eye. Because nerve cells are in a constant state of compression, and are unable to respond adequately to the increased loads due to the disturbance of the energy balance, depletion of secretory (mediator) function, the increase in the duration of the stimulus causes irritation in additional depletion makroenergeticheskie compounds that eventually leads to degenerative changes within the cell, with subsequent connective tissue its rebirth.
This method is based only on the use of domestic energy reserves of the body, does not provide a mild deficiency of microelements and biologically active substances.<> In accordance with this task, aimed at the creation of a method, which would have had greater functionality, including through the use of it in the early postoperative period, provided comprehensive impact of having a vascular, antispasmodic, analgesic effect, reduced the production of intraocular fluid, improved its outflow, circulation and trophic in the optic nerve and the retina was stimulated by their function, as well as intensified tissue metabolism, compensated for the deficiency of trace elements and biologically active substances.
To compensate for the deficiency of trace elements and biologically active substances, to enhance tissue immunity by adding a multifunctional component, which is the biologically active complex drug derived from the blood of deer antlers during the rut - "Pantonic (TU 9158-012-34616468-03).
To solve this problem in the treatment of patients with glaucoma, including the effects on the reflex zones currents supersonic frequency, proposed as the reflex zones of the use of the mucous membrane of the nasal passages and the upper cervical sympathetic nodes, with pre-applied to these zones gel "Partonic", and then to influence current of supersonic frequency power 1-2 kV is for 3-4 minutes on each of the four fields, if this course of treatment is 7-10 procedures carried out daily.
Reflex zones of the mucous membrane of the nasal passages and the upper cervical sympathetic nodes selected in accordance with the anatomical features of the arterial and venous circulation in the area of the orbit, reflexive relationship receptors of the nose with autonomic centers Cnsmin impact zone of the upper cervical sympathetic nodes is determined by the impulses of the aortic-carotid receptors, which contributes to enhanced blood circulation in the Central nervous system in General and the vessels of the eye. All the above was the basis of the selected complex physiotherapeutic treatment.
For carrying out the method is used, the apparatus Ultratone-AM, which generates a continuous sinusoidal oscillation frequency of 22 kHz and a voltage up to 5 kV.
The method is as follows.
The patient sits on the couch. On the area of the mucous membrane of the nasal passages causing gel drug "Partonic". The electrode of the device, "Ultratone-AM alternately injected into the nasal passages and affect the mucous membrane of the nose shock supersonic frequency power 1-2 kV for 3-4 minutes. Then using a small mushroom-shaped electrode affect the area of the upper cervical sympathetic nodes, which are also pre-lubricated with a gel Pantone is to", conduct impact current of supersonic frequency power 1-2 kV for 3-4 minutes on each field. The total time of exposure per procedure does not exceed 20 minutes. Treatment is 5-10 daily procedures.
Examples of implementation of the method:
Patient A., born in 1934, was in the ophthalmology Department at MONICA with 9.07.2004. on 27.07.2004 with a diagnosis of Open-angle 3 (a) glaucoma, primary cataract, complicated and high myopia in both eyes. Andb 12880.
Admission: visual acuity of the right eye with sph -6,0 D=count fingers at a person, the total field of view 55°, EB optic nerve 570 mA, kcsm the red stimulus 15 Hz, the green stimulus - 14 Hz. Visual acuity of the left eye sph -6,0 D=0.1, the total field of view -65°, EB optic nerve 510 mA, kcsm the red stimulus 18 Hz, the green stimulus 17 Hz.
Conclusion: there are significantly decreasing the excitability and conductivity of the optic nerve in both eyes, optic nerve atrophy stage 3.
Underwent surgical treatment of the right eye - revascularization of the choroid with the subsequent course of physiotherapy treatment: gel drug " Partonic" was applied to the mucous membrane of the nasal passages and upper cervical sympathetic nodes. Then the electrode apparatus "Ultratone-AM consistently introduced into the nasal passages and affected mucous Obol is CCW nose current of supersonic frequency power 1 kV for 3 minutes on each field. Then using a small mushroom-shaped electrodes affected zone of the upper cervical sympathetic nodes with a capacity of 2 kV for 3 minutes on each field. The course of treatment was 5 daily procedures.
At discharge: the visual acuity of the right eye sph -6,0 D=0.1 (increase of visual acuity), the total field of vision of the right eye increased to 120°, EB optic nerve of the right eye decreased to 370 mA, kcsm the red stimulus was increased to 20 Hz, the green stimulus was increased to 18 Hz. Visual acuity of the left eye remained the same, however, the total field of view was increased to 161°, EB dropped to 355 mA, kcsm the red stimulus was increased to 24 Hz, the green stimulus to 21 Hz. Conclusion: the observed improvement of conductivity and excitability of the optic nerves of both eyes after surgical treatment of the right eye and physical therapy.
Patient M., born in 1941, was in the ophthalmology Department at MONICA c29.06.2004. on 14.07.2004 diagnosed with narrow-angle 3 (C) glaucoma of the left eye, narrow-angle 1 (a) glaucoma of the right eye. Andb 12087.
Admission: visual acuity of the right eye of 0.9, the total field of view 495°, EB optic nerve 120 mA, kcsm the red stimulus 33 Hz, the green stimulus - 34 Hz. Visual acuity of the left eye=0.05 with sph -3,5D =0.1, the total field of view 85°, EB optic nerve 410 mA, kcsm the red stimulus 14 Hz, the green is timul 13 Hz.
Conclusion: there are significantly decreasing the excitability and conductivity of the optic nerve of the left eye, optic nerve atrophy 3 stage left eye.
Underwent surgical treatment of the left eye-revascularization of the choroid with the subsequent course of physiotherapy treatment: gel drug " Partonic" was applied to the mucous membrane of the nasal passages and upper cervical sympathetic nodes. Then the electrode was sequentially introduced into the nasal passages and worked on the mucous membrane of the nose shock supersonic frequency power 2 kV for 3 minutes. Then using a small mushroom-shaped electrodes impacted areas of projection of the upper cervical sympathetic nodes with a capacity of 2 kV to 4 minutes on each field. Treatment 5 daily procedures.
At discharge: the visual Acuity of the left eye improved to 0.08 with sph -3,5D=0.2, a total field of view was increased to 165°, EB decreased to 350 mA, kcsm the red stimulus was increased to 20 Hz, the green stimulus to 18 Hz. Conclusion: the observed improvement of conductivity and excitability of the optic nerve of the left eye after surgical treatment and physical therapy.
Thus, after surgical intervention, and treatment TNC on reflexogenic zones of the patients improved visual acuity, electric is the sensitivity of the optic nerve, Ccsm, expanded field of view.
The use of the proposed method will improve the efficiency of complex treatment of glaucoma, reduce the time of rehabilitation in the postoperative period, normalize intraocular pressure, improve visual function. The use of domestic physical therapy facilities and medical gel "Partonic" allows the use of this technique both in the inpatient and outpatient settings.
A method of treating glaucoma comprising impact on reflex zones currents supersonic frequency, characterized in that as the reflex zones of the use of the mucous membrane of the nasal passages and the upper cervical sympathetic nodes, with pre-applied to these zones gel "Partonic", and then affect the current supersonic frequency power 1-2 kV, for 3-4 min on each of the four fields, with the course of treatment is 7-10 procedures carried out daily.
FIELD: medical equipment.
SUBSTANCE: according to the first version the electrotherapeutic device has sections of power supply, pulse generation sections, bipolar output sections and alarm function operation time control section. Power supply sections intend for generation of high voltage signals with preset generation frequency, which signals come to bipolar output sections after pulse generation frequency are adjusted. Pulse generation sections intend for application of preset direct current to other sections of device after alternative current voltage is rectified by means of bridge. Bipolar output sections are made for choose of poles due to operation of switch after signals are amplified, which signals come from outputs of pulse generation sections. Power supply section and pulse generation section are provided for any pole. Any output terminal of bipolar output sections is provided with resistor and triangular pulse generator to exclude short circuiting. According to the second version, electrotherapeutic device has power supply for full-wave rectification ac circuit voltage and for application of preset direct current to other sections of device, central processor for controlling operations of device, indication section for representation of operations to be performed, control unit for introduction of control signals, buzzer section for generation of sonic signal of buzzer at moments of beginning and finishing of operation of device and at moment of introduction of control signals, output regulating section intended for adjusting signals, and output sections which has cascades. Pulse generation section serves for application of signals with specified generation frequency to output section after pulse generation frequency is adjusted. Output signal is provided with separate transformer and independent rectifying section for any corresponding cascade to get unipolar output signals. Device has sets, any of which set has pulse generation section and output section, which are connected in parallel to perform simultaneous selection of multiplicity of poles.
EFFECT: ability of elimination of short circuit; reduced time for treatment; improved efficiency of procedure.
5 cl, 5 dwg
SUBSTANCE: method involves talking to patient and parents for setting diagnosis. Detoxication, prohibitory and rehabilitative therapy is carried out in hospital. Basic therapy is administered with Clophellinum, Hemineurine, Tizercine, Galoperidol, Loperamide before beginning detoxication. Ultra-rapid opioid detoxication is carried out and vitamin and cardioprotector therapy is applied for 1-2 days after it is finished. Comatose atropine therapy and electric convulsion therapy are alternated every other day at the prohibitory therapy stage. Total number of procedures is equal to 5-6. Ozone therapy is applied every day at the same stage in 80 mg/l mode at a rate of 0.1 l/min. Premedication is carried out before electric convulsion therapy with 0.5 ml of 0.1% atropine sulfate solution, 2 ml of 2% Ditiline solution, 10-15 ml of 20% sodium oxybarbiturate solution. Transcrtanial electric stimulation is carried out at rehabilitation stage. Electric convulsion therapy is carried out once per two-week period during the whole period. Ozone therapy is carried out on the background of anti-depressant introduction twice per 10-14 days.
EFFECT: wide range of functional applications.
SUBSTANCE: method involves injecting membrane-associated antigen vaccine from destroyed tumor cells. Biopsy tumor cells taken from patient are used as raw vaccine material. Vaccine is produced by irradiating cell suspension with pulsating electric field having succession frequency and rectangular pulse duration equal to 35-50 Hz and 5-7 ms, respectively, specific current amplitude being equal to 300-500 mcA during 30-40 min in microelements presence. The injection is carried out by subcutaneously implanting incubator-carriers manufactured from porous titanium nickelide having vaccine deposited into the pores.
EFFECT: enhanced effectiveness of oncologic disease treatment.
SUBSTANCE: the present innovation deals with treating ischemic insult, especially at rehabilitation of patients at its acute phase. Along with medicinal therapy it is necessary to fulfill nervous-muscular electrostimulation (NES) of paretic extensors of fingers and wrist followed by evaluation of motor function. NES of paretic extensors of fingers and wrist should be started from the moment of establishing the fact of ischemic insult to be continued during 3-4 wk. Duration of 1 seance lasts for about 20-30 min twice daily. Impulses should be supplied every 4 sec at 2-sec-long duration. The innovation increases the quality of motor and functional reconstruction in post-insult patients due to changing the terms for the onset of NES technique towards its decreasing.
EFFECT: higher efficiency of reconstruction.
1 ex, 1 tbl
SUBSTANCE: method involves applying fractured bone fragments reposition at the first stage and implanting metal electrodes at the second stage into the osteolysis zone. Beck wires with dielectric coating are used as the electrodes. The wires are introduced transcutaneously in parallel to femur neck axis and mounted on epiphyseal germination zone with their working ends penetrating not less than 3 mm deep. Then, flexible electrodes are subcutaneously implanted in hip joint projection zone. Electric stimulator is connected to the skin ends of the electrodes. Pulsating current of negative polarity is supplied to intraosseous electrodes, whereas the flexible electrodes receive current of negative polarity from 5 to 10 mcA, frequency of 1 Hz and voltage of 8.8 V. Total duration and cross-section of rectangular pulses is not longer than 200 mcs. Pulsating electric current acts the whole day to achieve full closure of the germination zone.
EFFECT: enhanced effectiveness of treatment; prevented adverse side effects.
SUBSTANCE: method involves applying drug therapy under ischemic lesion focus state control with magnetic resonance tomography (MRT) being used. Bioenergetic evaluation of focus state, its size and cerebral blood circulation condition are evaluated in dynamics. Therapy without drugs is concurrently applied for observing ischemic lesion focus at the end of acute period using MRT-mode with suppressed signal from free liquid surface. The MRT observation is started at the first two days from the ischemic stroke beginning.
EFFECT: enhanced effectiveness of treatment.
SUBSTANCE: the present innovation deals with treating and rehabilitating patients after insult cases. Electrostimulation should be carried out due to transcranial impact with direct and impulse current with frontal-mastoidal disposition of electrodes, current power being about 2-3 mA, impulse current frequency being 77 Hz, duration being 3.5 msec. Simultaneously, one should affect peripheral nerves of paralyzed and healthy limbs with direct current of 60-90 Hz frequency and voltage up to 70 V. Moreover, at paralyzed limb polarity should be altered every 10-15 min. Therapy should be fulfilled by courses consisted of about 7-10 seances, each being of about 1.2-1.5 h. The innovation enables to increase hemodynamics and enhance cerebral circulation.
EFFECT: higher efficiency of therapy.
1 cl, 2 ex
FIELD: medicine; neurology.
SUBSTANCE: right and left forehead, cervical and temporal areas of brain are subject to simultaneous trans-cranial influence of amplitude-frequency-modulated magnetic field during 3 minutes and to amplitude-frequency-modulated electric waves onto mammiform appendices with modulation frequency of 3 Hz and current up to 100 mcA during 20 minutes. Then carotid and vertebral arteries are subject from the left and from the right to low-intensity IR-radiation laser with modulation frequency up to 3 Hz, depth of modulation up to 50%, power up to 50 J, wavelength of 960 nm from the right and from the left during 5 minutes. Then vision analyzer is subject to influence of amplitude-frequency-modulated low-intensity IR waves with modulation frequency up to 3 Hz, depth of modulation up to 50%, 850 nanometer's wavelength and with power up to 2 mW/cm2 during 30 minutes. Course of treatment consists of 15 procedures.
EFFECT: stronger metabolic processes in brain tissue; improved parameters of arterial and venous blood current, rheologic properties of blood; restored cortical neuro-dynamics.
SUBSTANCE: the present innovation deals with treating patients with the lesion of spinal cord of uninflammatory character. Electrostimulation should be carried out in three stages: at the first stage due to applying electrodes: anode-needle-electrode should be introduced into inter-spinous space along the middle line being below the site of lesion, and cutaneous electrode-cathode should be located in frontal-parietal area, in projection of motor and promotor cerebral areas. At the second stage, electrostimulation should be conducted by applying electrodes: cathode-needle-electrode by introducing into inter-spinous space along the middle line being above the site of lesion, and cutaneous electrode-anode should be located in projection of a nerve bundle under stimulation. At the third stage electrostimulation should be carried out by changing the polarity of electrodes and applying: electrodes anode-needle-electrode to be kept in inter-spinous space along the middle line being above the site of lesion, and cutaneous electrode-cathode should be located above affected muscles or in areas of affected sensitivity. The innovation enables to accelerate the reconstruction of the functions of spinal cord at its keeping.
EFFECT: higher efficiency of reconstruction.
FIELD: medicine, veterinary science.
SUBSTANCE: it is necessary to affect biologically active points (BAP) with current of 15-30 mcA, frequency of 8 Hz. The ratio of the duration of impulses of positive and negative current polarities corresponds to 1:1. The impact lasts for 2 min once daily. In case of femur fracture one should affect BAP 108 and 109, and in case of shin bones fracture - BAP 115 and 116. Therapy course lasts for 7 d. The method shortens terms of therapy due to applying the current of the above-mentioned parameters.
EFFECT: higher efficiency of stimulation.
1 dwg, 2 ex, 1 tbl
FIELD: chemical-pharmaceutical industry, pharmacy.
SUBSTANCE: invention relates to a pantohematogen-base medicinal formulation for external using that comprises the following components, wt.-%: dry pantohematogen, 0.01-6; polymeric gel-forming composition, 0.1-20, and water, the balance. Proposed medicinal formulation provides using pantohematogen an aqueous solution without addition of alcohol and therefore it can be used in cases wherein alcohol-containing formulations are contraindicative - in burns of different degree, small skin damages and others and can be used in treatment of patients showing intolerance to alcohol-containing preparations. Method for preparing the pantohematogen medicinal formulation for external using involves preparing "dry" pantohematogen aqueous solution in the ratio limits pantohematogen : water = (1:50)-(1:200) by weight and solution is kept under normal conditions for 1 h and filtered. Additionally an aqueous solution of rare-linked polymer is prepared in the ratio = (1:10)-(1:200) and an aqueous solution of neutralizing agent in the amount necessary for providing slightly alkaline medium of final solution. In the volume ratio of pantohematogen aqueous solution and rare-linked polymer in the ranges = (3:1)-(1:10) components are mixed and stirred to obtain the homogenous solution. Then neutralizing agent aqueous solution is added to a mixture and stirred to obtain homogenous solution with slightly alkaline reaction (pH = 6-8). The advantage of proposed technology in preparing the medicinal formulation involves its simplicity and providing prolonged fitness period.
EFFECT: improved preparing method.
6 cl, 1 ex
FIELD: medicine, cardiosurgery.
SUBSTANCE: the present innovation deals with complex procedures for carrying out open-heart operations associated with high blood losses and considerable requirement for blood-substitution therapy. It is necessary to carry out preoperational autoblood sampling in cardiosurgical patients due to a single exfusion of 5-10% volume of patient's circulating blood and its conservation, moreover, 1-2 d before autoblood sampling it is necessary to conduct total hypoxic sample, detect the values of oxygen balance and lactate concentration in blood serum and at its values being SpO2>85%, SvO2>60%, O2EI<30 and the absence of lactate concentration growth at the background of 40-min-long respiration with hypoxic gaseous mixture with 10%-content of oxygen one should consider tolerance to hypoxia to be high and sample autoblood at the quantity of 10% against total volume of circulating blood; at physiological ability of a patient to breathe for 40 min with hypoxic gaseous mixture with 12%-content of oxygen it is possible to consider tolerance to hypoxia to be average and sample autoblood at the quantity being not more than 7% against the volume of circulating blood, and at physiological ability of a patient to breathe with hypoxic gaseous mixture only at the content of oxygen being under 14% tolerance to hypoxia should be stated to be low and, thus, one should sample not more than 5% against the volume of circulating blood. The innovation decreases postoperational complications, increases efficiency of hemotransfusional therapy due to individualized approach for detecting optimal quantity of autoblood sampled.
EFFECT: higher efficiency of sampling.
SUBSTANCE: the suggested hemostatic material contains collagen and thrombocytic mass dried due to freeze drying and structured in formaldehyde vapors, moreover, it contains transfusion-unsuitable thrombocytes at the following ratio: collagen : thrombocytes = 100:(0.5-2.5). Additionally, this material may contain antiseptics or antibiotics of wide spectrum of action. The innovation enables to apply thrombocytes after cryodestruction, and, also, transfusion-unsuitable thrombocytes (overdue storage period), that is apply the material which is considered to be useless. The material suggested is of high hemostatic activity.
EFFECT: higher efficiency of application.
FIELD: medicine, infectious diseases.
SUBSTANCE: method involves carrying out the step-by-step treatment wherein the following agents are administrated at the first step in turn: inhibitor and activator of virus replication; hemosorption is carried out at the second step; reablement of immune system is carried out at the third step by using blood enriched with stem cells, and specific immunostimulation. Hemosorption is carried out by using columns wherein each comprises a matrix with agarose-immobilized ligands comprising, respectively: the first - specific antiviral antibodies, the second - CD4-receptors, the third - receptors raised to gamma-interferon, the fourth - receptors raised to Fc-fragment of immunoglobulin G, the fifth - antimicrobial proteins of mammalian origin, and blood enriched with stem cells is administrated by intravenous route. Invention promotes to the maximal sorption of HIV and its elimination, limiting the iatrogenic immunosuppression that, in turn, promotes to reducing risk for virus persistence in the patient body. Invention can be used in treatment of patients with AIDS.
EFFECT: enhanced effectiveness of treatment.
FIELD: medicine, ophthalmology.
SUBSTANCE: it is necessary to carry out complex therapy including introduction of lidase, tactivin, dexason, coffeinum, nootropil, halidor, emoxipin, proserinum, actovegin, vinpocetine, cerebrum compositum, mildronate, dibasol, Magne-B6 and gliatilin at certain dosages and ways of injection, in combination with hirudotherapy, electrostimulation of optic nerve, electrophoresis with lekosym and magnetostimulation in superciliary, frontal, parietal and occipital areas. The suggested innovation improves acuity due to improved microcirculatory and metabolic processes in encephalon and optic analyzer.
EFFECT: higher efficiency of therapy.
1 ex, 3 tbl
SUBSTANCE: the present innovation deals with treating diseases associated with affected tissue circulation. It deals with injecting mononuclear cells of donor's umbilical cord blood into the blood. Moreover, the above-mentioned donor's cells have got the set of antigens HLA-A, HLA-B, HLA-DR being distinct against the recipient's set of antigens HLA-A, HLA-B, HLA-DR by not less than four antigens. The quantity of introduced cells ranges 2.5 x 106 up to 10 x 106/kg body weight/d. Injection should be repeated 2-10 times at interval of 10-60 d. The innovation provides substitution of dead and/or recipient's regeneration-impotent cells with the above-mentioned donor's cells and enables to decrease the frequency of immunopathological reactions at decreasing the number of introduced donor's mononuclear cells.
EFFECT: higher efficiency of therapy.
2 cl, 8 ex, 1 tbl
SUBSTANCE: method involves determining lymphocyte CD 56+ in peripheral blood before planned pregnancy. The content exceeding norm, lymphocytoimmunotherapy courses are applied with donor lymphocytes. The courses are applied at the fifth-eighth day of fertility cycle until normal lymphocyte CD 56+ values become restored. Pregnancy being proved, lymphocytoimmunotherapy courses are applied with ultrasonic examination results having in view. Choriohypoplasia being available, the courses are applied every 2 weeks. Chorion thickness being in conformity with gestation age, the courses are applied every 3-4 weeks to 12-14 pregnancy weeks.
EFFECT: adequate chorion and placenta development.
SUBSTANCE: preparation has autologic hemopoietic stem cells separated from peripheral patient blood enriched in cells containing CD34 antigen in final concentration of (40-100)x106 cells/ml. Blood enrichment is carried out by introducing granulocyte colony-stimulating factor like Neupogen in glucose solution in intermittent mode according to known scheme. Method involves applying the claimed preparation.
EFFECT: reduced tissue incompatibility and transplant rejection; enhanced effectiveness of treatment.
9 cl, 1 dwg, 2 tbl
SUBSTANCE: method involves carrying out contact-mode laser photocoagulation with laser having wavelength of 1064 nm and power of 6-10 W. exposure time is equal to 2-4 s. Autoblood injections are additionally introduced before applying laser radiation treatment, in peripheral zone relative to hemorrhage source.
EFFECT: enhanced effectiveness in arresting gastroduodenal hemorrhages.
FIELD: medicine; medical engineering.
SUBSTANCE: method involves dipping plastic bags containing blood plasma frozen to -25 - -30°C and lower, into bath filled with water to achieve full thaw at water temperature not exceeding 8°C or at 35-37°C washing the bags with turbulent flow. The bags are arranged in chessboard order and defrosting process is carried out as follows. First, the bags containing blood preparations are defrosted to 0-4°C. The temperature being achieved is determined from water level reduction in the bath to a calculated value determined from formula Δh = n(Vfp - Vlp)/S, (1), where Δh is the given value of water level reduction in the bath when thawing the plasma, n is the number of bags containing frozen plasma, placed in the bath at a time, Vfp is the frozen plasma bag volume, Vlp is the liquid plasma bag volume, S is the bath area. Timer is switched on for a calculated time applied to bring the bags containing blood components to 7-8°C. Device has bath filled with distilled water, heating and cooling device temperature sensor and control circuit as well as mixer having electric drive connected to executive circuit of the control circuit and water level sensor connected to control circuit input. The bath has canals for letting water flow from bath end to compartment where the mixer is placed. The mixer is separated from the rest objects in the bath with vertical partition communicating with the bath via connecting hole in the lower part of the compartment. The control circuit comprises the timer.
EFFECT: accelerated defrosting process.
2 cl, 2 dwg, 1 tbl
FIELD: medicine, ophthalmology.
SUBSTANCE: it is necessary to conduct scanning laser impulse irradiation of newly formed corneal vessels with scattering light bundle for about 5-10 min at applying the following parameters: wave length 890-900 nm, irradiation power 1-5 W in impulse, the frequency of impulses 140-160 Hz and impulse duration 50-300 nsec. Then it is necessary to introduce 0.1-1%-aqueous solution of photosensitizer of khlorin type taken out of the group of photolon, radakhlorin or photoditasin, at the dosage of about 0.8-1.1 mg/kg. Then one should perform exposition of newly formed corneal vessels without light access for about 15-20 min. Then it is necessary to apply the gel based upon hyaluronic acid viscoelastic onto corneal surface, this gel should be chosen out of the group of chealon, viscoate or hyatulon and, moreover, it is important to locate a laser light-scattering device upon corneal surface. Laser irradiation of newly formed corneal vessels should be fulfilled with scattered laser radiation at the density of laser radiation energy being 30-60 J/sq. cm. The innovation provides high efficiency in destructing newly formed corneal vessels followed by technique of optico-reconstructive keratoplasty.
EFFECT: higher efficiency of photodynamic therapy.
1 cl, 2 ex