Device for making physiotherapeutic effect

FIELD: medicine.

SUBSTANCE: device belongs to wide spectrum of influence devices, which is able to make prophylactic and medicinal influence onto human body; in particular, it can be used for destroying benign and malignant tumors and other concentrated formations. Device for making physiotherapeutic effect has control unit and influence localization unit connected with influence localization area. It also has hard base and unit for movement along x, y and z coordinates. Physiotherapeutic device is made in form of frame mounted onto hard base for shift in linear coordinates x, y and z, and n physiotherapeutic influence sources. The sources are disposed along perimeter of frame, which frame is connected mechanically with corresponding outputs of shift unit along coordinates x, y and z. Inputs o shift unit are connected with corresponding outputs along coordinates x, y and z of control unit. Corresponding inputs of control unit are connected with additional outputs of shift unit along coordinates x, y and z. Control input of control unit is connected with output of influence localization unit.

EFFECT: improved efficiency of physiotherapeutic effect; reduced negative reactions of organs and tissues surrounding the area.

13 cl, 5 dwg

 

The invention relates to medicine, namely to devices of a wide range of actions, including preventive and curative physical effects on the human body and other biological objects. The invention can find application for physiotherapeutic influence the pathological lesions in the body, in particular for the destruction of benign and malignant tumors and other concentrated formations, such as stones in the internal organs. In addition, it can be used for stimulation and/or correction of the functional state of the body, prevention of various diseases and physical therapy, stimulating and vital activity of certain areas of internal organs and tissues.

In the prior art is widely known various devices to influence the pathological foci in living organisms, the principle of which is determined by the method of physical impact on pathological lesions, for example, ultrasound, magnetic fields, microwave currents, signals, radiation therapy, etc.

Wide application in medicine find technical means of radiation on tumors of internal organs, such as linear accelerators, gamma-AIDS, etc. frequently mentioned means of radiation near the actions used in combination with the introduction of medicines, chemotherapy, etc. for example, the known device that allows you to vary the dose depending on the individual parameters of the marginal increase blood flow in the exposure zone (patent RU №2088285, a 61 N 5/06, 1997.08.27), taking into account the neoplastic process (patent RU №2089247, AND 61 N 5/10, 1997.09.10), depending on other means of treatment given to a patient concurrently with radiation therapy (patent RU №2163823, AND 61 N 5/00, 2001.03.10).

However, in these devices for radiation exposure to high severity of radiation reactions and complications surrounding the hearth impact of organs and tissues, the maximum surface dose in the exposure zone.

A device for high-frequency therapy (patent RU №2048822, AND 61 N 1/04, 1995.11.27)containing electrodes with individual applicators in which to increase the degree of localization of high-frequency electric field in a given area of the body electrodes and bonded with them the walls of applicators mounted for movement.

However, in this device, the power of impact in a particular area is limited due to possible complications in the internal organs and in the surrounding pathological lesion tissues.

Known devices for therapeutic intervention, carries combined methods with radiation therapy, in which are recorded ajesty General toxic and radiation reactions in radiation therapy, therefore to mitigate the radiation damage of tissues on the area of irradiation is applied drug (patent RU №2089247, AND 61 N 5/10, 1997.09.10).

However, these devices also do not allow to sufficiently reduce the severity of General toxic reactions in patients caused by the use of radiation therapy in the internal organs and tissues, as the latter remain unprotected.

A device for the treatment of patients with malignant tumors containing the means of irradiation lesion, the unit determining the scope of neoplastic lesions and areas of its regional metastasis and a control unit that allows you to vary the parameters of radiation exposure and to manage the local impact on clinically defined pathological lesions (patent RU №2141366, AND 61 N 5/10, 1997.06.20). The specified device allows you to vary the amount of radiation from the lesser to the greater, for example, by summing the area of the pathological focus of the third part of the radical total focal dose. This reduces complications in the beginning of the exposure, creates a sharp gradient of doses between irradiated and publicenemy tissues, however, this device does not significantly reduce damage in the surrounding pathological lesion tissues and internal organs if the application required a radical doses for deterriorating results radioparadise.

A device for treatment of urolithiasis (patent RU №2125899, a 61 N 5/06, a 61 N 2/04, 1995.06.14), including the unit of electric shocks frequency 10-130 Hz and a scheme for the combined magnetic effect.

The specified device is also not devoid of the disadvantages of the above devices, as there is no possibility of applying the necessary concentration limits impacts in a localized area without negative reactions from others pathological lesion tissues and organs.

The closest in technical essence and the achieved result to the claimed system is the treatment of radiation therapy for exposure of the subject (patent RU 2091093 WITH 1 MPC6A 61 N 5/10 27.09.97)containing means for generating x-ray beam consisting of multiple x-ray beam generators placed around the subject, a computer device with a control unit and a memory unit, and means for tomographic imaging. This device uses a method of radiation therapy based on the irradiation subject effects modulated by the intensity of the scanning x-ray beam, the detection of the last radiation and sequential actuation of the x-ray beam generators.

A disadvantage of the known device is the lack of efficiency associated with the abnormal detection of the pathological focus and methods of influence on him. This device must modulate the x-ray beam at a frequency suitable for the application of microwave signal in a particular place or places within the entity, to scan the subject to determine which of the microwave frequency or frequencies will be useful. However, in this device there is no concentration of energy in the pathological focus, which reduces the efficiency of the device as a whole.

The main task to be solved by the claimed invention is a device for physiotherapeutic effects, allowing to increase the efficiency while reducing negative reactions to physiotherapeutic effect surrounding the lesion tissues and organs.

The problem is solved in that in the known device for physiotherapeutic effects containing apparatus physiotherapy impact made in the form of a frame and n sources physiotherapy impacts along the perimeter of the frame, the control unit and block the localization effects connected with the zone of localization effects, introduced a rigid base and the block move in the x, y, z, while the frame is of Parata physiotherapeutic effects, mounted on the rigid base can move in linear coordinates x, y, z, mechanically connected with the corresponding outputs of the block move by coordinates x, y, z, the input of which is connected to the corresponding outputs on the coordinates x, y, z control unit, the inputs of which are connected with the corresponding additional output block move by coordinates x, y, z, while the control input of the control unit is connected to the output of the localization effects.

Sources physiotherapy interventions may be made in the form of small-sized electronic guns, or current generators of super-high frequency, or optical quantum generators, or generators of ultrasonic vibrations, or any other sources of physical therapy effects depending on the desired effect.

In addition, it is possible to identify sources of physical therapy effects in any combination in the case of application, for example, combined treatment methods.

Source type of physical therapy effects is chosen depending on the desired effect on the pathologic lesion or stimulation of the functional state of the organism. If necessary, the destruction of tumors can be used radioactive sources or x-ray exposed the Oia. In the case of using such a key factor in treatment, as termoustoychivee on the tumor, can be used radiators in the form of microwave oscillators in the frequency range from units to tens of gigahertz, or compact electron gun. In the case of exposure to concentrated education such as stones in the internal organs, can be used generators of ultrasonic vibrations.

It is advisable to perform a frame in the form of a ring or a hemisphere covering the upper surface of the rigid base.

A rigid base may be perforated for use impacts along the entire perimeter of the frame.

On the ring, it is advisable to install telescopically retractable rod, each of which can be installed source physiotherapeutic effects.

While the sources of therapeutic effects must be installed on the ring or telescopically retractable rods so that directed them signals the impact formed a cone, the base of which is the circle bounded by the ring, and the vertex is the intersection point of rays or signals.

The control unit may be in the form of a memory block of the coordinates x, y, z, the signal processing unit of the sensor coordinates x, y, z, block comparison of the coordinates x, y, z, the imp is United in a schema comparison for the x coordinate, schema compare for the y coordinate and the comparison circuit for the z coordinate, each of which has direct and inverse inputs, which respectively direct and inverse inputs of the block comparison of the coordinates x, y, z, and block amplifiers made in the form of first, second and third amplifiers, the group of outputs of the memory block of the coordinates x, y, z are connected with the related direct inputs of the block comparison of the coordinates x, y, z, the group of inputs of the signal processing unit of the sensor coordinates x, y, z is a group of inputs of the control unit, and a group of outputs the signal processing unit of the sensor coordinates x, y, z are connected with the corresponding inverse inputs of the block comparison of the coordinates x, y, z, and the outputs of the block comparison of the coordinates x, y, z are connected to the corresponding inputs of the block amplifiers whose outputs are the outputs of the coordinates x, y, z control unit, and the input of the memory block of the coordinates x, y, z is a control input of the control unit.

Block move by coordinates x, y, z can be connected in series for each of the coordinates of the motor, a sensor coordinate frame, the first output of which is connected to the gearbox and helical gears, while the inputs of the motors for each of the coordinates are the corresponding inputs of the unit peremeshany the coordinates x, y, z, shaft helical gear on each of the coordinates are the corresponding outputs of the block move by coordinates x, y, z, a second set of outputs of the sensor coordinate frame are the corresponding additional output block move by coordinates x, y, z.

Distributed surface and interstitial physiotherapeutic effect, carried out by executing the structure of the device so that the pre-mixing of the signals of the sources of exposure at the point of intersection, which is then installed in the location of the nidus, or another area of impact, pre-localizable linear coordinates x, y, z, allows us to concentrate physiotherapeutic effect the required power in the place of localization effects with minimum doses in the surrounding area of influence organs and tissues.

The device, in which apparatus physiotherapy action is made in the form of a frame with distributed it n sources physiotherapy impacts can be moved in longitudinal and transverse direction left or right along the corresponding coordinates x, y, z, mounted on rigid base on which to place the patient within the ring, a control unit connected to the unit, move the ring on the corresponding coordinates x, y, z, improves the efficiency impacts, focusing the maximum signal in a particular zone of influence. This physical impact, taking into account distributed around the perimeter of the frame (or arc - half of the circumference of the ring) n sources of exposure beams or signals are merged into one region according to certain coordinates x, y, z, minimizes both surface and interstitial dose effects on the internal organs and, thus, to reduce the adverse reactions on the body, which are defined as radiation reactions and other complications from exposure, for example from overheating surrounding the pathologic lesion tissue by irradiation of high-frequency signals.

1 schematically shows a General view of the structure and the flowchart of the device.

Figure 2 schematically shows a structure diagram of the device.

Figure 3 shows the functional diagram of the control unit.

Figure 4 (a, b, C) shows a schematic representation of the design block navigation coordinates x, y, z, and the mechanics of its movement.

Figure 5 shows a schematic picture of the device frame with telescopic rods (a) and (b).

The device (1) contains the device physiotherapy impact made in the form of n sources 1 physiotherapeutic influence the of conduct, evenly spaced around the circumference of the frame, made in the form of ring 2 on the telescopic sliding rod 3, and block 4 of localization effects, optically associated with the region of localization effects. The ring 2 is installed on a rigid base 5 can move in the longitudinal direction (x-coordinate) and the upward and downward direction (the y coordinate) and right-left (z coordinate). The device also includes a control unit 6 connected to the unit 7 move by coordinates x, y, z, the group of outputs of which are connected mechanically with the ring 2.

The control unit 6 (figure 2) contains the memory unit 8 of the coordinates x, y, z, block 9 of the signal processing of the sensor coordinates, the unit 10 comparison performed in the comparison circuit 10-1 on the x-coordinate of the comparison circuit 10-2 on the y coordinate, the comparison circuit 10-3 z coordinate, unit 11 amps, made in the form of the first 11-1, 11-2 second and third 11-3 amplifiers, and the outputs of the memory unit 8 of the coordinates x, y, z are connected respectively with direct inputs x, y, z corresponding schemas comparison 10-1, 10-2, 10-3 on coordinates x, y, z, the group of inputs of block 9 of the sensor signal of the coordinates x, y, z is the corresponding group of inputs of the control unit 6, and a group of outputs of block 9 of the sensor signal of coordinates connected with the corresponding inverted inputs x, y, z schema comparisons 1-1, 10-2, 10-3, the output of the comparison circuit 10-1 on the coordinate x is connected to the input of the first amplifier 11-1 whose output is the output x of the control unit 6, the output of the comparison circuit 10-2 on the y coordinate is connected to the input of the second amplifier 11-2, the output of which is output from the control unit 6, the output of the comparison circuit 10-3 z coordinate is connected to the input of the third amplifier 11-3 whose output is the output z of the control unit 6, the input unit 8 to the memory of the coordinates x, y, z is a control input of the control unit 6.

Travel unit 7 (figure 2) at the coordinates x, y, z are made in the form of the first 12-1, 12-2 second and third 12-3 helical gear, the first 13-1, the second 13-2 and third 13-3 gears, the first 14-1, the second 14-2 and 14-3 third sensor coordinate frame 2, the first 15-1, second 15-2 and third 15-3 motors, the inputs of which are respectively the inputs x, y, z unit 7 move by coordinates x, y, z, a, the outputs of the motors 15-1, 15-2, 15-3 connected respectively to the inputs of the first 14-1, the second 14-2 and the third 14-3 sensor coordinate frame 2, the first outputs are connected respectively to the first 13-1, the second 13-2 and third 13-3 gearboxes. The second outputs of the sensors 2 coordinate frame 14-1, 14-2, 14-3 are respectively additional outputs of the block 7 to move in the coordinates x, y, z.

Sources 1-n physiotherapeutic effects, for the threaded depending on the desired dosage and prescribed therapeutic or preventive actions, can be made in the form of small-sized electronic guns, generators currents microwave, ultrasonic vibrations, etc.

Sources 1-n physiotherapeutic effects before operation of the device is positioned so on the ring 2 or telescopically retractable rods 3 that are directed from them signals the impact formed a cone, the base of which is the circle bounded by the ring 2, and the top of the point of intersection of beams or signals.

A rigid base 5 perforated in cases where the exposure is carried out using sources that are installed around the perimeter of the frame, made in the form of a ring 2 comprising a rigid base. The ring 2 may be made in the form of a hemisphere covering the upper surface of the rigid base 5. This rigid base 5 may be made solid.

When conducting radiation therapy device may be provided with an additional ring to absorb the rays passing through the tumor or other pathological lesion of the patient.

A device for physiotherapeutic effect works as follows.

The frame is made in the form of a ring 2, is mounted on the rigid base 5 can move in the longitudinal, transverse and left-right direction in linear coordinates x, y, z. Ring 2 connect the network mechanically rigid helical gear 12, connected in series with the gear 13, the sensor coordinate frame 14 and motor 15. For the organization of high precision movement on the corresponding linear coordinates x, y, z are used stepper motors or brushless direct current.

Ring 2 with a stiff helical gears 12-1, gearbox 13-1, sensor coordinate frame 14-1, motor 15-1, still attached to the rigid base 5 can move along the rigid base 5, the coordinate x (forward-backward). Accordingly, by using helical gears 12-2, gearbox 13-2, sensor coordinate frame 14-2 and motor 15-2 is moving the rings up and down the line the y coordinate. Similarly moves the ring to the left to the right on a linear coordinate z by means of a screw transmission 12-3, gearbox 13-3, sensor coordinate frame 14-3 and motor 15-3.

Before you begin the ring is in original condition so that the point of convergence (it is strictly fixed relative to the ring and is specified when setting up the apparatus) was located in the middle of the rigid base for the coordinates x and z, and 10-15 cm above the rigid base for cordinate. And this point is taken as the beginning of the fixed coordinate system. Sources physiotherapy exposure to 1-n d who should be set no telescopically retractable rods 3 thus, to be directed from them signals the impact formed a cone, the base of which is the circle bounded by the ring, and the top of the point of intersection of the rays or other signals of physical therapy effects.

Telescopic rod 3 that are sources of impact 1-n, ejected automatically or manually by an operator.

The patient is placed on the hard ground inside the ring 2. If after placing the patient on the hard ground, the impact zone was hit in the beginning of coordinates, then all the signals in x, y, z at the input of the control unit 6 will be zero and the ring will not move. In all other cases, it will move to the desired length.

Using the unit 4 containment impact zone is established exposure - pathological focus or area of stimulation of a functional condition of an internal organ or tissue in the coordinates x, y, z of the patient. Unit 4 the localization effects can be performed with ultrasound computer tomograph, which determines and enters into the control unit 6 information on pathological lesion or other area of the desired impact in three linear coordinates x, y, z. Ultrasonic tomograph, in the particular case of execution of a block of localization effects, associated with the control unit of conventional electrical connections, and ve is hichina electrical signals, transferred from unit 4 localization in the control unit 6 is proportional to the coordinates x, y, z. In addition to the ultrasonic scanner it can be any imaging system images the impact zone, for example, the device x-ray tomography, nuclear magnetic resonance system.

When the power is on, the motors 15 are rotated, causing the ring 2 is moved in all three coordinates x, y, z. The signals at the outputs of the sensors 14 coordinate frame, which is the additional output unit 7 move by coordinates x, y, z arrive at the inputs of the control unit 6, which is the corresponding inputs x, y, z unit 9 of the sensor signal of the coordinates x, y, z.

Pre-installed in the patient's pathological focus or area of influence to stimulate specific body to organize the necessary physiotherapy, represented in linear coordinates x, y, z with unit 4 the localization effects, is fed to the control input of the control unit 6, which is the input of the memory unit 8 of the coordinates x, y, z. The memory unit 8 of the coordinates x, y, z contains at least three memory cells in x, y, z, the output of which signals the magnitude of which correspond to certain coordinates on the x, y, z, in the digital code received is on the corresponding direct input schema comparison x (10-3), on (10-2) z (10-1).

On the inverted inputs of the respective schemes comparison 10 for x, y, z signals by coordinates x, y, z with the respective outputs of block 9 of the sensor signal of the coordinates x, y, z, is proportional to the value of coordinates on the x, y, z of the point of convergence, which in the initial state is equal to zero. At the outputs of block 10 comparison of the coordinates x, y, z are formed signals proportional to the difference between signals from the memory unit 8 of the coordinates x, y, z and block 9 of the sensor signal of the coordinates x, y, z. When matching on the signal level on the direct and inverse inputs of each of the schemes comparison unit comparing the 10 signals on their outputs become equal to zero, which leads to stopping of the motors 15 unit 7 move by coordinates x, y, z.

Stop a mechanical transmission systems unit 7 move by coordinates x, y, z means that the area of the pathological focus or the center for preventive action of the patient coincides in linear coordinates x, y, z with area information-rays or other physical signals.

The device may be provided with an additional ring (not shown)rigidly connected with the ring 2 and serving for the absorption signals of radiation diverging after the point of intersection of the rays.

In that case, if the frame is made in the form of a ring 2 and covers estae base 5, the latter is perforated.

The device can be used combined influence on pathological lesions or other areas of impact, therefore, on telescopic rods 3 can be installed at the same time, for example, sources of radiation and microwave or in a different combination.

You can also move a rigid base with a stationary frame-ring 2 in the longitudinal, transverse and upward-downward.

Sources 1-n physiotherapeutic effects connected after installation of the pre-calculated exposure modes, characterized by the intensity and time of exposure. Modes of exposure are determined depending on the magnitude of pathological or other source of exposure and selected physical method of exposure.

The claimed device allows a wide range of physiotherapeutic effects on different types of tumors and other concentrated formations in the internal organs.

The device allows you to change the range of impacts from the promotion and revitalization of healthy cells to destruction of tumor cells.

The claimed device can specifically and effectively influence the pathological lesions in the body or other areas requiring preventive or STI is wirausaha impact, minimizing the negative reaction of the surrounding hearth impact of organs and tissues.

1. A device for physiotherapeutic effects containing apparatus physiotherapy impact made in the form of a frame with n sources physiotherapy exposure, located on its perimeter, the control unit and block the localization effects, characterized in that it introduced a rigid base and a block move by coordinates x, y, z, while the frame of the apparatus physiotherapy impact, installed on the hard ground with the ability to move in linear coordinates x, y, z, mechanically connected with the corresponding outputs of the block move by coordinates x, y, z, the input of which is connected to the corresponding outputs on the coordinates x, y, z control unit, the inputs of which are connected with the corresponding additional output block move by coordinates x, y, z, while the control input of the control unit is connected to the output of the localization effects.

2. The device according to claim 1, characterized in that each of the sources physiotherapy action is made in the form of electron gun.

3. The device according to claim 1, characterized in that each of the sources physiotherapy action is made in the form of a generator of ultra high frequency currents.

4. The device according to claim 1, trichomania fact, each of the sources physiotherapy action is made in the form of optical quantum generator.

5. The device according to claim 1, characterized in that each of the sources physiotherapy action is made in the form of a generator of ultrasonic vibrations.

6. The device according to claim 1, characterized in that the frame is made in the form of a ring.

7. The device according to claim 1, characterized in that the frame is made in the form of a hemisphere, covering part of the rigid base.

8. The device according to claim 1, wherein the hard base is perforated.

9. The device according to claim 6, wherein the ring further comprises a rod, each of which has a source of physical therapy effects.

10. The device according to claim 9, characterized in that the rod is made telescopically retractable.

11. The device according to claim 10, characterized in that the sources of therapeutic effects telescopically mounted on sliding rods with the possibility of forming their signals cone, the apex of which is the point of intersection signals.

12. The device according to claim 1, characterized in that the control unit contains a memory block of the coordinates x, y, z, the signal processing unit of the sensor coordinates x, y, z, block comparison of the coordinates x, y, z, made in the form of the comparison circuit for the x-coordinate of the comparison circuit is on the y coordinate and the comparison circuit for the z coordinate, each of which has direct and inverse inputs, which, respectively, direct and inverse inputs of the block comparison of the coordinates x, y, z, and the unit amplifiers made in the form of first, second and third amplifiers, the group of outputs of the memory block of the coordinates x, y, z are connected with the related direct inputs of the block comparison of the coordinates x, y, z, the group of inputs of the signal processing unit of the sensor coordinates x, y, z is a group of inputs of the control unit, and a group of outputs of the signal processing unit of the sensor coordinates x, y, z connected to respective inverted inputs of the block comparison of the coordinates x, y, z, and the outputs of the block comparison of the coordinates x, y, z are connected to the corresponding inputs of the block amplifiers whose outputs are the outputs of the coordinates x, y, z control unit, and the input of the memory block of the coordinates x, y, z is a control input of the control unit.

13. The device according to claim 1, characterized in that the block move in the x, y coordinates, z is made in the form connected in series for each of the coordinates of the motor, a sensor coordinate frame, the first output of which is connected to the gearbox and helical gears, while the inputs of the motors for each of the coordinates are the corresponding input block move by coordinates x, y, z, shafts, vintagered for each of the coordinates are the corresponding outputs x, y, z block move by coordinates x, y, z, and the second outputs of the sensor coordinate frame are the corresponding additional output block move by coordinates x, y, z.



 

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4 dwg, 1 tbl

FIELD: medicine.

SUBSTANCE: method involves administering Wobenzyme combined with brachytherapy with radiomodification and transpupillary thermotherapy or combined with isolated transpupillary thermotherapy. When combined with brachytherapy with radiomodification, Wobenzyme is given 2 days before brachytherapy at a dose of 3 pills 3 times a day with the exception of 8 h before fixation and removal of β-applicator. Next to it, Wobenzyme is given at a dose of 4-6 pills 3 times a day during 3 months. Then, the dose is reduced by 2 pills every month at the fourth, fifth and sixth months. Adjuvant transpupillary thermotherapy is carried out 6 months later after brachytherapy. Wobenzyme is given at a dose of 2-3 pills 3 times a day 2 days before transpupillary thermotherapy. Then, the dose is 4-6 pills 3 times a day during 2 months with following dose reduction by 3 pills every month to prophylactic dose of 1 pill a day. When carrying out isolated transpupillary thermotherapy, Wobenzyme is given in the same mode that it was the case when carrying out adjuvant transpupillary thermotherapy after brachytherapy. To prevent metastasis occurrence, Wobenzyme administration is continued at a dose of 1 pill 7 days every month during the first year and at a dose of 1 pill 3 days every month during the second observation year.

EFFECT: accelerated resorption processes; reduced risk of radiation treatment complications.

FIELD: medicine, oncology.

SUBSTANCE: one should carry out radiation therapy with quick neutrons 6.3 Mev twice weekly in two stages: at the first stage it is necessary to prescribe 3-4 seances of neutron therapy at interval of 48-72 h directly onto area of tumoral relapse and onto surrounding normal tissues at the distance of about 3-5 cm against tumoral foci, single focal dosage being 1.6-2.0 Gy, relative biological efficiency corresponds to 2.91-2.79, onto the skin - 2.0-2.2 Gy, up to total focal dosage being 6.6±1.5 Gy, onto the skin - 8.3±1.3 Gy, at the second stage it is necessary to carry out gamma- or electronic therapy at single focal dosage being 2.0-3.0 Gy, 5 fractions weekly, moreover, total course dosage of neutron-photon irradiation per a focus corresponds to 60 Gy by isoeffect at duration of irradiation course of about 20-25 d.

EFFECT: higher efficiency of therapy.

2 dwg, 3 ex

FIELD: medicine.

SUBSTANCE: assembly can be used for revealing pathologic cells when determining elemental composition of matter from gamma-radiation, for example, from 59Fe isotope stored in mammal gland. Gamma-spectrometry assembly for inspection of mammal gland has patient's chair, collimators, radiation protection, drives for moving chair, spectrometer, ionizing radiation detectors and control board. Collimators are disposed in radiation protection aid and they are made of material which well absorbs ionizing radiation. Collimators are mounted for direction of radiation onto ionizing radiation detectors. Collimators and ionizing radiation detectors are mounted in unit with cavities in form of cups for placing objects to be tested.

EFFECT: improved radiation safety.

2 cl, 3 dwg

FIELD: medicine, ophthalmology.

SUBSTANCE: before the onset of protonotherapy one should surgically withdraw eyelids beyond bony orbital borders for the purpose of complete prevention of complications associated with blepharoirradiation at conducting protonotherapy and creating conditions for the next valuable prosthetics. Thus, after external canthotomy one should make two through vertical incisions of the upper eyelid up to bony orbital border at developing a P-shaped fragment of the upper eyelid, moreover, internal incision should be made about 2-3 mm laterally against the upper lacrimal point, and external one - against internal edge of canthotomic incision. Then one should apply per one P-shaped suture onto both external and internal angles of the fragment, moreover, it is necessary to puncture in needles from cutaneous side of the fragment by applying ligatures in palpebral thickness at capturing a cartilage and perform punctures out into intramarginal space. Similarly, one should apply a single similar P-shaped suture onto the lower eyelid in area of its middle part. The ends of P-shaped sutures should be fixed without tightening frontal and buccal skin, correspondingly. Before carrying out the seance of protonotherapy it is necessary to tighten sutures till eyelids come beyond bony orbital borders, and on finishing the seance of protonotherapy sutures should be weakened till the moment of palpebral juncture.

EFFECT: higher efficiency of prophylaxis.

1 cl, 1 dwg, 1 ex

FIELD: medicine, oncology.

SUBSTANCE: one should carry out morphological testing of therapy results, moreover, in the course of therapy it is necessary to conduct immunohistochemical study for the levels of Ki-67 antigen expression, markers to protein-negative regulator of apoptosis: p53 and Bcl-2 and the level of melanoma marker expression HMB-45 and at decreased levels against the values in untreated tumors it is possible to state upon therapy as efficient. The innovation enables to achieve high clinical efficiency of therapy due to applying neoadjuvant autohemochemotherapy in combination with radiation therapy.

EFFECT: higher accuracy of detection.

2 ex

FIELD: medicine.

SUBSTANCE: method involves applying chemotherapy and/or multi-fraction irradiation daily in two fractions. Variable volume irradiation is carried out during 12 days under radiation dose of 16-20 Gy with dose power being control by means of control unit at the level of 0.18-0.22 Gy/min. Systemic irradiation of tumor dissemination region is carried out with single fraction through a large field. Lymph nodes locally participating into the process and clinically proved lesion foci are irradiated with another fraction after 4.5-6 h long reparation period to total dose equal to 22-24 Gy with unit dose equal to 1.4-1.6 Gy. Medicated sensibilization is carried out during the reparation period.

EFFECT: enhanced effectiveness of treatment; high frequency of no relapse cases.

3 dwg, 1 tbl

FIELD: medical engineering.

SUBSTANCE: device has elongated bioabsorbing carrier containing radioactive sources inside. The sources are separated with spaces. The elongated bioabsorbing carrier is solid composition molded around radiation sources. Moulds are used when producing cells containing radioactive material. A set of radioactive grains is introduced into the mould. Liquid material is introduced into the mould for making it harden. Hardened product is removed from the mould. To treat patients for states manifested as response to radiation therapy, a cell containing radioactive material is arranged in immediate proximity to the patient body zone under treatment for time period required for providing therapeutically effective radiation dose.

EFFECT: produced easy-to-use cell having rigid coating stable in operation.

24 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: method involves applying preradiation topometry with irradiation fields being formed. Irradiation is carried out 5 times a week from two opposite fields to reach total radiation dose of 50 Gy under unit focal dose being equal to 2 Gy. The irradiation is applied from rectangular fields having the following boundaries. The lower one is upper edge of the second lumbar vertebra body. The upper boundary is 10 cm higher than the lower one. The right one is 2 cm far from vertebral column contour to the right. The left boundary is 15 cm far from the right one. Removed stomach bed, paracardial lymph nodes, lymph nodes of lesser omentum, gastropancreatic ligament along the left gastric and splenic arteries to the splenic porta and celiac lymph nodes. The tumor propagating over abdominal or supradiaphragmatic esophageal segments, additional anterior and posterior rectangular irradiation fields are formed with paraesophageal and bifurcational nodes being included into the zone.

EFFECT: reduced risk of complications after radiation treatment; maximum amount of healthy tissues retained.

3 cl, 3 dwg

FIELD: medicine.

SUBSTANCE: method involves doing surgical intervention including gastropancreaticoduodenectomy with pancreatojejunal anastomosis being created. Small fraction radiation therapy course is preliminarily applied during 3 weeks before operation by treating pancreas projection region and lymph discharge path with gamma-radiation at total dose of 35-40 Gy. Hemcytabine is introduced into gastroduodenal artery at a dose of 0.2 g/m2 in radiopaque oil during operation before carrying out gastropancreaticoduodenectomy.

EFFECT: enhanced effectiveness of treatment.

FIELD: medicine.

SUBSTANCE: method involves administering chemotherapy in 1-5 days long courses. The treatment is accompanied with subtotal patient body irradiation with field concentrated in the area from diaphragm vault to feet everyday once a day before every chemotherapy course. Irradiation dose is equal to 0.1 Gy within total dose of 0.8 Gy. The combined treatment is repeated with 2-3 months long pauses to reach remission or total dose of 1 Sv in subtotal patient body irradiation.

EFFECT: enhanced effectiveness of treatment.

FIELD: medicine.

SUBSTANCE: method involves consuming nutrient substances and energy as electromagnetic radiation. Energy unbalance symptoms appearing, the organism is treated with infrared radiation and visible light having spectrum of solar radiation reaching earth surface and/or radiation emitted by artificial light sources of wavelength in 0.65-1.2 mcm range and/or infrared radiation of heated things of wavelength in 1.21-10.0 mcm range.

EFFECT: enhanced effectiveness in treating chronic and acute diseases.

2 cl

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