Method for control and dynamic survey for the state of tympanic cavity according to preliminarily fulfilled opening
SUBSTANCE: one should carry out perforation of tympanic membrane with a laser beam at wave length being 0.97 mcm to fulfill an opening of about 2-3 mm diameter. The method provides prolonged terms for the survey and decreased traumatism in a child due to no necessity in conducting repeated tympanotomies in case of survey even during short period of time, moreover, the opening made should be remained for the terms up to 3-4 wk at their further independent closing without development of cicatricial alterations upon a patient's tympanic membrane.
EFFECT: higher efficiency of control and survey.
The invention relates to medicine, namely to control and monitor the status of the tympanic cavity by a pre-made hole, and can be used in ENT clinics and ENT departments in the treatment of patients with diseases of the middle ear.
The known method of monitoring the condition of the tympanic cavity through the ear tubes, followed by the introduction in the section of Teflon tubes [Yakushenkova A.P. "Exudative otitis media in children (diagnosis and treatment), dis. CMN, Moscow, 1996, p.78-84].
The method requires a high level of proficiency in a microscopic technique, in order not to injure important in functional relation to the anatomical structures of the middle ear. Myringotomies incise not capable of long-term remain open, and the introduction of the shunt on long-term atrophy of the tympanic membrane, which loses its conductive properties and durability. Made incise and entered into the tube require special care, as it can clog the dried exudate. Sometimes the shunt spontaneously falls in the external auditory meatus. Furthermore, the method is quite traumatic.
The purpose of the invention is the increase of the period of observation of the tympanic cavity and reducing trauma b is rabanni membrane and the anatomical structures of the middle ear.
This objective is achieved in that the perforation of the eardrum carried out by a laser beam with a wavelength of 0.97 μm, with the formation of holes from 2 to 3 mm.
For a long time a hole in the eardrum, allowing to dynamically observe the tympanic cavity and to produce therapeutic measures in it. In addition, the method does not require the introduction of ventilation tubes.
The method is as follows.
Before carrying out the manipulation of the patient conduct a General analysis of blood and urine, the assessment of the flora of the nasopharynx, the definition of allergic status; endoscopic examination of the nasal cavity, nasopharynx and ear; audiological research, impedancometry and rhinomanometry.
After examination under mask anesthesia perform endoscopic laser tympanotomy with the formation of holes with a diameter of 2 to 3 mm, and the wavelength of the laser beam of 0.97 μm.
In the future, due to continued open within 3 weeks of the hole in the eardrum implemented dynamic observation of the tympanic cavity and have the best options conservative treatment.
The patient Svetlana M., age 8. Clinical diagnosis: Bilateral exudative otitis media. Adenoids 2 degrees.
Complaints of hearing loss is over 2 years old.
When otoscopy: eardrum drawn, dull, translucent yellow contents.
Endoscopic examination: in the lumen nasopharyngeal adenoid vegetations 2 degrees.
Audiogram: bilateral conductive hearing loss of 2 degrees.
Tympanogram: type "B".
The hospital conducted podnagotnaya endoscopic adenotomy.
In order to ensure the continuous monitoring of the condition of the tympanic cavity decided to make bilateral endoscopic laser media by the claimed method.
After giving laryngeal mask anesthesia under the control of the rigid optics the patient underwent bilateral endoscopic laser media in the anterior-inferior tympanic membranes, after which a thin suction apparatus is made to aspirate fluid from the tympanic cavity. Then through the holes with a syringe in the tympanic cavity is entered in 1 ml hydrocortisone, and 1 ml of chymotrypsin.
On the 1st day after the operation, when otoscopy eardrum pale contours are visualized, no blood in the anterior-inferior quadrants foreseeable holes of 2 mm diameter, with sharp edges, tympanic cavity is not changed, ear bones and promontorium very well seen from two sides, no exudate.
On the 3rd day re-introduction b Rabanne cavity of the drug hydrocortisone at a dose of 0.5 ml, and the blowing of the auditory tube by Politzer pneumomassage eardrum; endoscopic examination membranes pale, holes remain open, accumulation of fluid in the tympanic cavity no. Marked improvement in hearing from two sides by 10-20 dB.
On the 6th day inspection of the tympanic membrane pale, the contours are determined, the hole diameter is 1.5 mm to the right and 1.7 mm to the left, the entrance to the tympanic cavity free from two sides, exudate in the middle ear cavity was not found.
On the 10th day when otoscopy tympanic membrane pale, diameter tympanoctomys holes to the right of 1.1 mm, left 1.3 mm, tympanic cavity without the negative dynamics; produced pneumomassage eardrum.
On the 16th day after the operation, the diameter of the holes in the ear-drum to the right and to the left is 0.2 mm and 0.4 mm, respectively, membranes clearly contribute, exudate absent.
Finally closing tympanostomy holes happened to the 21-th day; tympanic membrane pale, clear contours, cicatricial changes.
The course of treatment the patient was 21 days.
After treatment according to the audiogram hearing is restored to normal values, tympanogram - type ' a'; the child was discharged from outpatient hospital under observation.
The Patient Anatoly Is., 12. Clinical diagnosis:
The right recurrent otitis media.
History of frequent otitis, hearing loss.
When otoscopy: eardrum drawn to the right, dull, contours are not clear.
Endoscopic examination: the mouth of the auditory tube is covered with a tube tonsils.
Audiogram: right-sided conductive hearing loss 2 degrees.
The hospital conducted endoscopic laser destruction of the tubal tonsils.
In order to ensure the continuous monitoring of the condition of the tympanic cavity and holding of medication made right endoscopic laser media by the claimed method.
Under the mask anesthesia, hard-optics produced right endoscopic laser media in the anterior-inferior quadrant of the tympanic membrane; then made through the hole made the drug fluimucil is an antibiotic in the dose of 1.5 ml.
On the 1st day after surgery when viewed eardrum without signs of inflammation in the anterior-inferior quadrant is visualized hole with a diameter of 2.5 mm; tympanic cavity anatomical structures of the middle ear intact mucosa of the middle ear several hyperamylasemia, pathological secret is not found.
On the 3rd day when otoscopy eardrum pale contours foreseeable, tympanoctomys hole with sharp edges, the tympanic cavity is well visible, hyperemia of the mucous sharply decreased, detachable none; re-introduction into the cavity of the middle ear through the remaining hole of the drug fluimucil is an antibiotic in a dose of 1 ml; also produced pneumomassage the eardrum to the right.
On the 5th day when endoscopic examination of the right ear marked reduction of the diameter of the holes of 0.6 mm, eardrum pale, contoured, tympanic cavity without evidence of inflammation, discharge does not contain. There has been improvement in hearing from the right by 10 dB.
On the 9th day when inspecting the diameter tympanoctomys hole is 1.4 mm, eardrum pale contours foreseeable, the mucosa of the tympanic cavity pink; re-introduction of fluimucil-antibiotic at a dose of 0.5 ml, and did the blowing off of the auditory tube by Politzer pneumomassage eardrums.
On the 12th day when otoscopy eardrum pale contours intact, the hole diameter is 1 mm, edges crisp, dry; tympanic cavity without evidence of inflammation. Produced by the blowing of the auditory tube and pneumomassage eardrums.
On the 16th day during the inspection. is fair membrane pale, contoured, diameter tympanoctomys hole is 0.4 mm Conducted the hearing blowing pipes and pneumomassage eardrums.
Final closure tympanostomy occurred on the 20th day of treatment, eardrum pale contours very well seen, cicatricial changes.
The treatment of the child was 20 days.
According to rerun the test the child's hearing is restored to normal values. The patient was discharged from the outpatient hospital under observation.
The patient Nicholas D., 7 years. Clinical diagnosis:
Left exudative otitis media. Adenoids 3 degrees.
History of frequent colds, ear infections, tinnitus, hearing loss.
When otoscopy: eardrum dull, paths cleared, her mobility is limited, translucent exudate.
Endoscopic examination: in the lumen nasopharyngeal adenoid vegetations of 3 degrees.
Audiogram: left conductive hearing loss 2 degrees.
Tympanogram: type "B".
The hospital conducted podnagotnaya endoscopic adenotomy.
In order to ensure the continuous monitoring of the condition of the tympanic cavity and holding her rehabilitation decided to make a left-endoscopic laser media by the claimed method.
After the issuance of the mask on the goat under the control of the rigid optics the patient underwent bilateral endoscopic laser media in the anterior-inferior quadrant of the tympanic membrane, then the electric pump with thin atticum probe made aspiration of thick fluid from the tympanic cavity and the introduction made through the hole with a syringe 1.5 ml hydrocortisone, and 1 ml of trypsin.
On the 1st day after surgery with endoscopic examination of the left ear is defined pale with indistinct contours eardrum with very well seen in the front-lower quadrant tympanocentesis hole diameter of 3 mm, the mucosa of the tympanic cavity hot pink, promontorium and ear bones intact, revealed a small accumulation of mucous discharge.
On the 3rd day after surgery with otoscopy eardrum pale contours are not defined, the hole in the eardrum wealthy, tympanic cavity without obvious signs of inflammation, contains a small amount of mucus; us re-aspiration of mucus and introduction to the tympanic cavity 1 ml hydrocortisone, and 1 ml of trypsin performed through tympanostomy.
On the 6th day inspection of the eardrum pale contours are visualized, the diameter tympanoctomys hole is 2.3 mm, smooth edge; mucosa of the tympanic cavity pink, not swollen; produced by injecting auditory tube by Politzer pneumomassage eardrum. According to the diagramme marked improvement in hearing left by 10-20 dB.
On the 10th day when otoscopy eardrum pale diameter tympanoctomys hole is 1.9 mm, the mucosa of the tympanic cavity pink, exudate does not accumulate; continuing through the hole into the cavity of the middle ear is entered 0.5 ml hydrocortisone; produced by injecting auditory tubes and pneumomassage eardrums.
On the 14th day inspection of the eardrum pale contours are determined, the diameter of tympanostomy is 1.5 mm, detachable no, tympanic cavity without inflammatory changes; produced by injecting auditory tubes and pneumomassage eardrums.
On the 18th day of observation at otoscopy diameter tympanoctomys holes is 1 mm, eardrum pale, contoured, detachable none; produced by injecting auditory tubes and pneumomassage eardrums.
On the 22nd day of the diameter of tympanostomy amounted to 0.4 mm, eardrum pale, clear contours; produced pneumomassage eardrums.
On the 25th day tympanoctomys hole closed completely; when otoscopy eardrum pale, clear contours, scarring us not identified.
The course of treatment the patient was 25 days.
These audiograms and tympanograms after treatment within normal limits. The child was discharged from the hospital with pollingstation hearing under outpatient supervision.
Despite its apparent simplicity, the method is very effective, does not require repeated surgical interventions, easily tolerated during the whole period of observation and treatment (up to 3-4 weeks)until full self-closing hole in the eardrum.
However, the claimed method of control and dynamic observation of the tympanic cavity is not obvious for specialists working in this field.
This, in particular, by the fact that even with a relatively simple surgical interventions on the tympanic cavity, if necessary, monitor the status of the repair process until the proposed method had repeatedly, and sometimes repeatedly perform the media due to self-close the hole in the eardrum.
Moreover, due to the frequently observed spontaneous closure of the hole in the eardrum, is accomplished by conventional incisio, often had to ReWire all the forced tympanopuncture and ear tubes, exposing the child to the risk of secondary bacterial complications.
Previously to prevent premature closure is made in the eardrum holes recommended to leave it for the required period shunt, i.e. thin tubes, specialno made for this purpose from titanium or plastic.
Currently, when the surgical intervention with the application of the proposed method such necessity is not present.
Not obvious for specialists working in this field, was the fact of spontaneous closure of the hole in the eardrum performed using a laser tympanostomy, without any scarring, while at repeated regular incised, as a rule, these changes take place.
In some cases these changes are serious enough and with the further growth and development of the child behave differently, until the dysfunction of the hearing.
Therefore, the absence of any scarring on the eardrum is very important in prognostic terms.
Despite the simplicity, the claimed method was developed to some extent unexpected, however, this in no way reduces its exceptional value for pediatric otorhinolaryngology.
The simple way available for implementation in the present description and will find, as we hope, the widespread use in pediatric otolaryngology.
Control method and dynamic observation of the tympanic cavity by a pre-made hole, characterized in that, to increase the observation time and reduce trauma, perforation is urabandai membranes carried out by a laser beam with a wavelength of 0.97 μm, with the formation of holes from 2 to 3 mm.
FIELD: veterinary science.
SUBSTANCE: it is necessary to carry out complete dissection of gilts' carcasses to remove organocomplex and investigate vertebral column. Acute rachitis form should be diagnosed by detecting thickenings in intervertebral cartilaginous disks, in thoracic and lumbar departments, particularly. The innovation enables to decrease economical losses.
EFFECT: higher efficiency and accuracy of diagnostics.
2 dwg, 2 ex
FIELD: medicine, stomatology.
SUBSTANCE: it is necessary to determine the quantity of dental covering according to dyestuff intensity by a 5-point scale. Bridgework denture should be dyed with certain 0.1%-rhodamine solution. The quantity of dental deposits should be detected due to ultraviolet light spectrum of about 300-400 nm. The innovation enables to detect both the quantity and the quality of dental deposits and evaluate the index of oral hygiene in patients with bridge work dentures, provides dyeing picture in ultraviolet light only and requires no additional washing.
EFFECT: higher accuracy and efficiency of detection.
1 cl, 3 dwg
SUBSTANCE: method involves carrying out diagnostic examination of ophthalmic diseases. Health state of organism systems and organs is additionally estimated. Systems and organs having deviations from norm are selected and bound to channels P, RP, C, R, F. Actions are applied by showing images to patient. Image colors exert curative action in accordance to color tables of Ancient China philosophy and WU-SING doctrine. The color exerting curative action upon a channel is selected to be the same with the color exerting curative action upon organ belonging to the channel. Detected pathologically changed organ or system is acted during the first treatment course. The channel having the detected pathologically changed organ or system, is treated at the second treatment course. The following treatment courses deal with the channels conjugated to the first one corresponding to WU-SING doctrine. The total treatment per each organ or system and each channel course is 10 procedures long.
EFFECT: enhanced effectiveness of treatment with the whole organism state taken into consideration.
1 dwg, 7 tbl
FIELD: medicine, cardiology.
SUBSTANCE: one should carry out discriminant analysis to create discriminant function with coefficients of independent variables, such as: arterial hypertension, anemia, gynecological disease, hyperglycemia, cholelithiasis, smoking, lipid disorders, pathological menopause, excessive body weight and thyroid diseases. It is necessary to evaluate every risk factor and solve the function. At the value of function being above 1.710 one should predict the absence of atherosclerotic lesion of coronary vessels. The innovation enables to establish the probability of atherosclerotic lesion of coronary vessels or its absence according to risk factors in female patients due to carrying out discriminant analysis.
EFFECT: higher accuracy of prediction.
FIELD: medicine, photodynamic therapy.
SUBSTANCE: one should treat affected part with a preparation containing 5-aminolevulinic acid, cover with a light-tight bandage to keep for about 4-6 h. Then comes fluorescent diagnostic survey followed by a 2-fold laser vulval irradiation at the dosage of about 30-75 J/sq. cm at 1-h-long interval that totally corresponds to 100-150 J/sq. cm. The suggested innovation enables to carry out curative process in soft mode, decrease the risk for further development of vulval cancer, achieve healing without any cicatrices and avoid such side effects as phototoxicity.
EFFECT: higher efficiency.
1 cl, 3 ex
SUBSTANCE: method involves determining preoperative factors like clinical stage of prostate neoplasm, prostate-specific antigen level, prostate capsule invasion with tumor from rectal finger palpation test data, prostate capsule invasion with tumor from transrectal ultrasonic examination data, the number of positive biopsy bars in carrying out transrectal prostate biopsy, neoplasm differentiation stage from transrectal ultrasonic examination, malignance degree from transrectal ultrasonic examination according to Glisson scale. Histological examination results are evaluated after previously done transurethral prostate resection. Postoperative factors like pathological neoplasm development stage, malignance degree from morphologic examination data according to Glisson scale and prostate tumor invasion into seminal vesicles from morphologic examination data are also determined. Remote metastasis index is calculated from formula M=0.24xT - 0.010xP + 0.87xR + 0.02xC + 0.15xB - 1.12xD + 0.07xKG + 0.38xH - 0.38xpT + 0.11xPG + 2.02xV, where M is the remote metastasis index, T is the clinical prostate neoplasm stage: 1 - T1; 2 - T2; 3 - T3; P is the prostate-specific antigen level before operation in ng/ml; R is the prostate capsule invasion with tumor according to rectal finger palpation test data: 0 - no invasion; 1 invasion available; C is the prostate capsule invasion with tumor according to transrectal ultrasonic examination data: 0 - no invasion; 1 invasion available; B is the number of positive biopsy bars in carrying out transrectal prostate biopsy: 1-6; D is the neoplasm differentiation stage from transrectal prostate biopsy: 1 low level differentiation degree;2 - moderate level differentiation degree; 3 - high level differentiation degree; KG is the malignance degree according to transrectal prostate biopsy data using Glisson scale 2-10; H is the histological examination after previously done transurethral prostate resection: 0 - not applied; 1 - benign prostate hyperplasia; 2 - prostate adenocarcinoma; pT is the pathological neoplasm development stage: 1 - pT2a; 2 - pT2b; 3 - pT3a; 4 - pT3b; PG is the malignance degree from morphologic examination data according to Glisson scale: 2-10; V is the prostate tumor invasion into seminal vesicles from morphologic examination data: 0 - no invasion; 1 invasion available; and if M>-1.55, remote metastasis formation is predicted.
EFFECT: high accuracy of prognosis.
SUBSTANCE: method involves carrying out chronobiological studies in morning, day and evening hours. 9-11 measurements are taken for studying intraocular pressure values with 1-2.5 h long pauses during 4-5 days with 2-3 different measurements in succession falling on each day.
EFFECT: high accuracy of diagnosis.
SUBSTANCE: method involves determining concentrations of carcinogens like aniline, toluyline, diethyl alanine, diphenyl and 1-naphtholamine in urine and urodynamic disorders and proliferative urothelium activity from Ki-67 expression degree data. High carcinogen concentrations and urodynamic disorders being detected apart from the fact of tumor removal and unchanged mucosa biopsy, transurethral prostate resection or urinary bladder neck resection is carried out. Next, liquid consumption increase in postoperative period and carcinogen contact reduction are advised. Three months later, control study is carried out. Carcinogen concentration level remaining high and no proliferative urothelium activity reduction being observed on the background of urodynamic disorders, cystectomy is to be repeatedly carried out.
EFFECT: enhanced effectiveness of treatment; high accuracy of diagnosis.
FIELD: medicine, diagnostics.
SUBSTANCE: due to spectrophotometry on should study body biological material to detect the concentration of porphyrin in tissues of biological material and compare it values against the standard. As biological material one should apply that part of the tissue at patient's body where spectrophotometric investigation should be carried out in vivo. Moreover, One should affect this part with low-intensity laser radiation, wave length corresponds to one of the maximums of protoporphyrins' absorption range. One should determine the amplitude of fluorescence radiation of this part. As a standard for comparison one should take the amplitude of fluorescence of protoporphyrin IX that models the concentration of protoporphyrin in blood erythrocytes ranged 100-1500 mcg/l and more. At equality of amplitudes it is necessary to establish concentration of proptoporphyrin IX in blood erythrocytes of biological tissue under testing. Moreover, wave lengths corresponding to maximums of absorption range of protoporphyrins correspond to 337, 370, 405, 532, 632 nm. The innovation enables to considerably simplify the investigation of values that indirectly characterize lead concentration in tissues and, thus, total degree lead intoxication in patients with the risk of lead intoxication.
EFFECT: higher efficiency of diagnostics.
1 cl, 1 ex
FIELD: medicine, oncology.
SUBSTANCE: one should carry out immunohistochemical and morphological tumoral study. At values of antigen KI-67 expression level being below 10%, mutated gene-suppressor P53 being below 10% and mitotic activity in the tumor being below 10 mitoses per 10 vision fields one should predict favorable prognosis of the disease. At values of Ki-67 being above 10%, P53 being above 10% and mitotic activity in tumor being above 10 mitoses per 10 vision fields one should predict unfavorable prognosis of the disease in question. The innovation enables to obtain quantitative objectivity of the results achieved.
EFFECT: higher accuracy of prediction.
1 dwg, 2 ex
FIELD: medicine, clinical toxicology.
SUBSTANCE: at patient's hospitalization one should gather the data of clinical and laboratory values: on the type of chemical substance, patient's age, data of clinical survey and laboratory values: body temperature, the presence or absence of dysphonia, oliguria being below 30 ml/h, hemoglobinuria, erythrocytic hemolysis, exotoxic shock, glucose level in blood, fibrinogen and creatinine concentration in blood serum, general bilirubin, prothrombin index (PTI), Ph-plasma, the state of blood clotting system. The state of every sign should be evaluated in points to be then summed up and at exceeding the sum of points being above "+20" one should predict unfavorable result. At the sum of "-13" prediction should be stated upon as favorable and at "-13" up to "+20" - prediction is considered to be doubtful.
EFFECT: higher accuracy of prediction.
2 ex, 3 tbl
SUBSTANCE: method involves studying blood samples with venous blood mixed with vital stain like methylene blue. Degree of vital stain absorption by erythrocytes is determined by applying photocolorimetry. The value drop being more than 25%, extracorporal detoxication is to be predicted as ineffective.
EFFECT: simplified method.
SUBSTANCE: method involves evaluating prognostic signs and calculating their prognostic weight. Consciousness disorders and diagnosis set at prehospital stage are used as the prognostic signs. Calculations are carried out from formula: lethal outcome %= -15.99+19.1•C+14.7•DS-2.79•C•DS, where C is the ranged consciousness disorder degree, DS is the diagnosis set prehospital stage. The higher is the value, the higher is lethal outcome probability.
EFFECT: accelerated and simplified prognosis method.
SUBSTANCE: method involves evaluating proliferating processes by calculating index of positive cell nuclei (Ki-67). The Ki-67 value being from 6 to 16%, erosive ulcerating stomach lesions accompanied by stomach hemorrhage and hemorrhagic shock is to be predicted. The value being from 17 to 30%, erosive ulcerating stomach lesions without hemorrhage is to be predicted.
EFFECT: high accuracy of prognosis.
FIELD: medicine, urology.
SUBSTANCE: the present innovation deals with differential diagnostics of prostatic cancer and other prostatic diseases at the stage of primary inspection. The method includes the detection of PCA and calculation of probability coefficient for prostatic cancer (PCC) by the following formula: where e - the foundation of natural logarithm (e=2.718…), PCA - the level of total blood PCA in ng/ml, V - patient's age in years. At PCC value being above 0.2 one should diagnose prostatic cancer and to establish final diagnosis one should perform polyfocal prostatic biopsy. The method enables to increase accuracy of diagnostics at decreased number of unjustified prostatic biopsies.
EFFECT: higher efficiency of diagnostics.
SUBSTANCE: method involves determining homeostasis values and absolute number of neutrophils and lymphocytes in particular. Low neutrophil number being determined in a child during a number of years and low number of lymphocytes in the persons from the nearest child surrounding, the persons are to be examined for given psychosomatic pathology availability with following medical treatment to be applied to eliminate the detected pathology and to normalize homeostasis values and lymphocyte number among others.
EFFECT: enhanced effectiveness of prophylaxis.
SUBSTANCE: method involves measuring radio signals and low frequency spectra of signals emitted by oral cavity organs and tissues in maxillofacial area. Decoding and comparison of the spectra to healthy organs and tissues spectra is carried out. Then, modulated information signals in infra-low frequency bandwidth corresponding to healthy organs and tissues signals are applied. Low frequency radio signals and spectra are measured. Treatment with modulated signals in infra-low frequency bandwidth is applied directly to organ or its location zone via skin.
EFFECT: enhanced effectiveness in diagnosing and treating oral cavity organs and tissues in maxillofacial area.
5 cl, 3 tbl
FIELD: medical engineering.
SUBSTANCE: device has bottom and cover joined in inseparable way so that no chance is available to mismatch covers belonging to different containers. The bottom and internal part of cover are lined with sponge so that the allergenic disks are kept in uniformly wetted state. Grate with holes is attached to lower sponge, the holes narrowing downward as cones so that the allergenic disks are kept in stable vertical position.
EFFECT: simplified access to disks using forceps; excluded misidentification risk.
5 cl, 6 dwg
FIELD: medicine, operative gynecology.
SUBSTANCE: at final stage of laparoscopic operation for 5-7 min one should introduce 16 U lidase in 1 ml 2%-lidocaine solution into uterine mesentery from both sides, and then, by not removing a needle - a half of single dose of antimicrobial preparation in 1 ml 2%-lidocaine solution, then in postoperational period - an antimicrobial preparation applied during laparoscopy lymphotropically under mucosa of lateral vaginal arch from both sides for 5-7 d once daily and one antimicrobial preparation - intravenously for 5-7 d, moreover, as antimicrobial preparations one should apply gentamicin, metrogyl and other preparations permitted for intravenous application. The present innovation stimulates lymphatic drainage in area of inflammation and activates interstitial humoral transport of antimicrobial preparations that, in its turn, favors complete sanitation of inflammation foci and prophylaxis of disease relapses.
EFFECT: higher efficiency of therapy.
1 cl, 1 ex
SUBSTANCE: method involves applying biological indicator as mixture composed of 0.1% aqueous solution of amino acids: leucine, glycine, proline, serine, phenylalanine, histidine, oxyproline, arginine, glutamic amino acid and aspartic amino acid, 0.5% aqueous solution of neuromediators like dopamine and histamine, 12% aqueous solution of magnesium sulfate in proportion of amino acids : neuromediators : magnesium sulfate = 4:1:5. Indicator kept on neck surface in thyroid gland projection during 3-5min. It is dried at T=+35-40°C, studied in polarized light with quartz compensator. Columnar, columnar-and-striated, sheaf-like crystals and discharged polygonal variegated chambers being observed, thyroid gland hyperfunction is to be diagnosed.
EFFECT: high accuracy of diagnosis.