Method for controlling of arthropod pests, composition for insecticidal and arachnicidal application, methods for controlling of sucking lice, flies, mites, and cockroaches

FIELD: method for controlling of arthropod pests.

SUBSTANCE: claimed method includes application in environments of pests of germinal calls thereof effective amount at least one vicinal diol of formula R(OH)2 selected from group containing diols, wherein R represents aliphatic hydrocarbon chain with the proviso that carbon atom in the chain adjacent to diol functional group is not substituted with ethyl and chain skeleton contains 8-20 carbon atoms. Composition for insecticidal and arachnicidal application containing abovementioned diol of formula R(OH)2 also is disclosed. Methods for controlling of sucking lice, flies, mites, cockroaches, and pests from group comprising Pediculus humanus, Dermatophagoides pteronyssinus, and Musca domestica.

EFFECT: death or non-vitality of pests after treatment.

26 cl, 4 tbl, 4 ex

 

This invention relates to the use of the replacement of hydrocarbon compounds, in particular vicinal diols, such as 1,2-ALCALDIA for combating arthropod pests.

Background of the invention

There is a need in the class of pesticide remedies that can kill a wide range of conventional arthropod pests of humans, domestic animals and cattle and especially pests phyletically classes Arachinida (ticks and mites) and Jnsecta (cockroaches, fleas, flies, Chechulina, lice). Because of the close relationship of these parasites with the organisms on which they parasitize, i.e. human or animal, to perform any practical problems such funds should be relatively non-toxic to the host body. In addition, in agriculture and gardening, there is a need in the class of pesticide remedies that can kill a wide range of arthropod pests that live on the leaves.

Mainly that the pesticide, in any case, was environmentally friendly (i.e. biodegradable).

Developed and sold as a pesticide means a large number of chemical compounds. However, only a few of them satisfy three criteria: (1) General toxicity against arthropod pests; (2) relatively low toxicity related and humans and domestic animals; and (3) good degradability.

The objects of the invention

The object of the present invention are alternative pesticide remedies that will eliminate or reduce at least some of the disadvantages of commercially available at the present time preparations. In particular, the object of this invention is a method of controlling arthropod pests.

Brief description of the invention

It is now established that vicinal diols very well satisfy the desired criteria. In particular, the current study showed that some compounds of the class of vicinal diols chemical formula R(OH)2where the hydroxyl group is vicinal position and R represents a hydrocarbon chain, which does not necessarily derivatization or substituted, exhibit excellent effectiveness as pesticides desired quality. The determining factor of this invention is the limited number of carbon atoms in the R group. However, good results were observed in those cases where the compound contains at least one hydrocarbon chain length n+2 atoms, where the value of n is preferably equal to at least 2 carbon atoms and vicinal hydroxyl groups occupy the end position, preferably hydroxyl gruppenfoto in the 1,2-positions, so diol forms a head group and a lipophilic tail. When changing the value of n there are different activity. This leads to a preference among them and the differences in the activity of the compounds with lower alkyl groups compared to compounds with higher alkyl groups (C6and above). Therefore, n can have a value up to 20, but compounds in which n has a value from 2 to 12, inclusive, are of the greatest interest. Such diols are chiral in nature, and, for example, in the case of 1,2-diols second carbon is a chiral center. The present invention can usefully be applied racemic mixture, however, the individual optical isomers (enantiomers) or a mixture containing a larger amount of one or more individual optical isomers can also be useful for the purposes of this invention. For example, it is shown that the efficiency of both enantiomers of 1,2-decanediol against lice is comparable with the efficiency of the racemic mixture, the test results of which are shown in the tables below.

The use of 1,2-alcaldias to control bacterial infection has been described. In the patent application of Japan No. JP 50-15925/ (publication No. 51-91327 Kazunori) revealed that 1,2-ALCALDIA, in particular homologues of medium chain length (n=5-9), are effective bacterial plankton is staticheskimi and fungistatic means of General application. In U.S. patent No. 4049830 (Pugliese) describes the use of 1,2-alcaldias to sterilize the nipples of the cow as a treatment for prevention of bacterial mastitis cows. In U.S. patent No. 6123953 (Greff) describes the local application of 1,2-diols to control bacteria that cause skin diseases, including mastitis, acne and dandruff. In addition, in European patent application EP A (Agostini, Cupferman) describes cosmetic preparations containing 1,2-alkyldiol as antibacterial means.

In GB 687850 (Airs) described the use of some vicinal diols as insect repellents in combination with known insecticides that do not contain solvent. The possibility of using vicinal diols as the active ingredient for the control of pests through their destruction or the destruction of their female germ cells (ova) before this time were not considered. In U.S. patent 4368207 (Lover, Singer et al.) describes the use of a number of monohydroxy alcohols to fight lice and their eggs and mites (mites). Similarly, in UK patent 1604856 (Lover, Singer et al.) describes the use of neficiary diols, in particular, 1,3-diols. In the mentioned patent proposes the use of such compounds for the control of ectoparasites and their female germ cells.

It is now established that vicinal diols, p is edocfile embodiment of readily available 1,2-diols, have a wonderfully elevated pesticide properties compared with monohydroxy alcohols or nevizualnye dialami. 1,2-ALCALDIA can be used to destroy a wide range of conventional arthropod pests, especially arachnids insects such as ticks and mites, and insects, such as flies, cockroaches, Chechulina, lice, and can be shown activity against their female germ cells. In addition, it is established that they can be subjected to decomposition and largely acceptable as useful pesticides for application in various fields.

Although the potential and efficiency of themselves vicinal diols proven so selected diols themselves are useful, in most cases, the target pests can be effectively destroyed their diluted solutions, and for some purposes a preferred form of delivery will offer additional technical advantages.

Thus, in accordance with this invention are also drugs that are suitable for contact application of such vicinal diols or their derivatives containing at least one vicinal diol in a physiologically acceptable medium, for control of specific animal and human diseases, mediated by pests, including the contamination of the head or a lice, infection carpeted lexicom, sheep scab, caused by the tick-borne infection (sheep-scab mite infection) infection is associated with meat flies (blow-fly strike).

Usually drugs will contain only the preferred compositions of the vicinal diols or in combination with suitable auxiliary additives, when necessary, and a carrier suitable for delivery of an effective amount of vicinal(data) diol(s) in place of pest infestation. Typically the carrier will be selected to ensure prolonged contact with the target pest. Depending on the target intrusion carrier can be a finely ground solid or liquid and may be selected from a powder, resin and water or organic liquids. Hence, suitable for the preparation of the drug and excipients may be selected from liquid fillers, solid carriers, auxiliary additives, emulsifiers, dispersants, resins, gums, adhesives, solvents and fillers.

The pesticide composition for delivering an active substance can be appropriately prepared in the form of a drug selected from a solution, dispersion, emulsion, finely powdered, paste, aerosol, cream, foam, substrate with a coating, for example, adhesive paper, pellets or blocks, for example, as bait for traps. Liners is qualified specialist will be necessary to select a physiologically favorable or acceptable carrier, when the pest must be disposed directly on a living organism, the host, and may choose such media of pharmaceutically acceptable carriers, in particular, intended for local use, to obtain creams, gels, pastes and ointments, aerated (foam/mousse) song, or fine powders, for example, talc.

Hereinafter the invention will be described in more detail using the example if necessary with reference to the accompanying drawings.

Figure 1 is a graph of the values LC50for a number of 1,2-diols against a lice person (Pediculus humanus).

Figure 2 is a graph showing the dependence of the activity of the eggs of lice, processed dialami, from the length of the chain diols.

The results are given below will serve to illustrate the efficiency of the selected vicinal diols against a number of pests, but they should not be considered as a predefined limit to their effectiveness only in respect of these or other organisms. Data on the effectiveness of selected vicinal diols in this description is not intended to exclude from the scope of the present invention similar except specifically mentioned herein, and you should pay attention to the claims, the following description that opredelyaetsya of the present invention.

Example 1:

Effectiveness against Pediculus humanus

This example shows the pesticide effectiveness of the compositions of this invention in relation to a lice person (Pediculus humanus) using vicinal diols in the tests in accordance with generally accepted methods of technical tests.

The data presented in tables 1 and 2 illustrate the unique nature of vicinal diols and the value of their effectiveness, where the values LC50some of diols and monohydroxy alcohols obtained in the tests of lice. The data of table 1 show the unexpected superiority of vicinal diols, compared with 1.3 - and other nevizualnye dialami. For example, 1,2-decanediol far exceeds 1,3-decanediol, and the table shows the advantage of vicinal connections in all the examples with the specified length of the chain.

The data in table 2 also show the superiority of vicinal diols on monohydroxy alcohols and some trioligy. The best efficiency of the tested monohydroxy alcohols is only 36% efficiency 1,2-decanediol. Excellent efficiency vicinal diols provides a useful action that can provide effective control of the pest even when used in less than ideal way to target organisms. Another advantage of these compounds is that he is, as shown, can easily metabolized normal soil bacteria, obtained from different regions, and therefore will easily degrade under dispersion in the environment.

Table 2
ConnectionThe value of LC50(mmol)Performance indicator (%)
1,2,3-HexanetriolNot evaluatedNot effective
1,2,6-HexanetriolNot evaluatedNot effective
2-Ethyl-1-hexanol3004
2-Ethyl-1,3-hexanediol6020
1-Decanol3532
2-Decanol3734
4-Decanol1836
9-Mission-1-ol3336
1,2-decanediol12100
3-Ethyl-1,3-decandiol6220
3-Octyl-1,2-decanediol9712
3-Ethyl-1,2-decanediolNot evaluatedNot effective
*The activity indicator represents the percentage of the values obtained LC50and values LC501,2-decanediol (=100%).

The effect of diol chain length on the activity shown in Figure 1, which shows a graph of the values LC50some of 1,2-diols against a lice of man.

These results indicate that 1,2-diols have pediculicide activity, With4-C16diols are active, thus are preferred With8-C14-diols, and the most preferred 1,2-octanediol, 1,2-decanediol and 1,2-dodecanediol.

Figure 2 shows the additional useful property of the object of the present invention, namely the inhibition of egg laying lice, which is an important distinction, because the inhibition or cessation of egg laying life cycle of the target organism is interrupted. This can be seen from the graph of the efficiency of some of diols, which shows that with increasing chain length diol activity eggs treated lice is significantly reduced. 1,2-Octandiol particularly effective to prevent the laying of eggs.

There Oficina activity, but studies of this aspect of the activity is ongoing, and results are not included in this description.

Example 2:

Effectiveness against Dermatophagoides pteronyssinus

Useful action is of vicinal diols is additionally illustrated by the results of the tests on the house dust mites Dermatophagoides pteronyssinus in accordance with generally accepted methods of technical tests. The mites are placed in a cotton wrap and dipped for a short time (5 seconds) in diluted solutions (2,5%) selected diols. Within 1 hour after immersion assess the condition of ticks and calculate the mortality. The results are presented in table 3 below, where for comparison the results of tests using carpet shampoo, permetrina insecticide and water (as a control).

Table 3
ProcessingMortality
1,2-Octandiol65
1,2-Decanediol95
Water3
3% carpet shampoo3
0.25% permethrin100

Example 3

Effectiveness against Musca domestica

An additional example of the application of the compounds of this invention represented by the test decane-1,2-diol against house flies in accordance with generally accepted method of technical tests of insecticides. 24 hours after treatment see more than 80% mortality, while decane-1,10-diol does not show insecticidal activity.

Example 4:

The preparation and use

Vicinal diols are easily incorporated into the composition of aquatic systems using nontoxic chorustorete is her such as isopropyl alcohol, or by using surfactants, such as Tween®. This allows you to easily enter them in a large number of products for home or industrial use, pesticides or cleaning agents. In particular, they can be entered in pharmaceutical preparations for use in humans or animals. The results of the treatment of lice and cockroaches preparations containing 1,2-octanediol or 1,2-decanediol presented in table 4 along with the results of tests of control systems solvent. In accordance with the generally accepted method of technical tests, insects immersed for several seconds in the test preparations and dried with blotting paper. Mortality for lice determined after 24 hours, cockroaches after 1 hour.

Industrial applicability

Based on the above advantages and pesticide properties of compounds used in described in this invention the compositions of the invention will be useful to apply in areas related to the presence of pests, such as agriculture, horticulture, sanitation, hygiene and veterinary medicine.

1. Method of combating arthropod pests, comprising applying to the habitat of the pests or their germ cells an effective amount of at least one Jared Lee loughner is a high diol R(OH) 2resulting pests are killed or become unviable, where specified vicinal diol selected from the group consisting of diols in which R represents an aliphatic hydrocarbon chain, provided that in the chain carbon atom, following the diol functional group, is not tilsammen, and this chain contains from 8 to 20 atoms.

2. The method according to claim 1, where vicinal diol consists of an aliphatic hydrocarbon chain containing n+2 atoms in its basis, where the hydroxyl vicinal diol occupy the end position, and thus the hydroxyl group of the diol and the carbon atoms to which they are attached, form a head group, and n represents an integer equal to at least 6.

3. The method according to claim 2, where n has a value of not more than 12.

4. The method according to claim 2, where the value n is an even number.

5. The method according to claim 2, 3 or 4, where the hydroxyl groups are vicinal diol take 1,2-position of the chain.

6. The method according to claim 1, where the hydrocarbon chain is branched.

7. The method according to claim 1, where these vicinal diols are 1,2-diols.

8. The method according to p. 7, where these vicinal diols are selected from the group consisting of linear aliphatic 1,2-diols with chain length from 8 to 14 carbon atoms.

9. The method according to claim 7, where these vicinal diols chosen by the group, consisting of linear aliphatic 1,2-diols with chain length from 8 to 12 carbon atoms.

10. The method according to claim 7, where these vicinal diols are selected from the group consisting of 1,2-octanediol, 1,2-decanediol and 1,2-dodecanediol.

11. Composition for insecticidal or ironizing applications, in particular for the suppression or destruction of arthropod ectoparasites, where as the active insecticidal or ironizing tools use effective amount of vicinal diol R(OH)2in which R represents an aliphatic hydrocarbon chain, provided that the carbon atom in the chain, following the diol functional group, is not tilsammen and the Foundation chain contains from 8 to 20 atoms, in combination with an auxiliary agent selected from the group consisting of liquid fillers, solid carriers, auxiliary additives, emulsifiers, dispersants, resins, adhesives, solvents and fillers.

12. The composition according to claim 11 in the form of the drug for delivery selected from the group consisting of a solution, dispersion, emulsion, finely powdered, gel, paste, aerosol, cream, foam, substrate coated granules and block.

13. The composition according to claim 11 or 12, where these vicinal diols are 1,2-diols.

14. The composition according to item 13, where these vicinal diols are selected from the GRU is dust, consisting of linear aliphatic 1,2-diols with chain length from 8 to 14 carbon atoms.

15. The composition according to item 13, where these vicinal diols are selected from the group consisting of linear aliphatic 1,2-diols with chain length from 8 to 12 carbon atoms.

16. The composition according to item 13, where these vicinal diols are selected from the group consisting of 1,2-octanediol, 1,2-decanediol and 1,2-dodecanediol.

17. The composition according to item 13, where vicinal diol is a 1,2-decanediol.

18. The way to deal with lice, including the use of a composition according to claim 11 or 12 in the areas of head lice infestation.

19. Way of dealing with lice for p, where this composition contains an effective amount of 1,2-decanediol.

20. The way to combat flies, including the use of a composition according to claim 11 in the focus of infection.

21. The way to combat flies, including the introduction of an infectious baits or traps treated with a composition according to item 11.

22. The way to combat mites comprising applying the composition of claim 11 in the focus of infection.

23. The way to deal with cockroaches, comprising applying the composition of claim 11 in the focus of infection.

24. The way to deal with cockroaches, including the introduction of an infectious baits or traps treated with a composition according to item 11.

25. The way to deal with pest selected from the group consisting of Pediculus humanus, Dermatophagoides pteronyssinus and Musca domestica, vkljuchajuwih the introduction to infectious pest compositions containing as the active ingredient vicinal diol selected from the group consisting of 1,2-octanediol, 1,2-decanediol, 1,2-dodecanediol.

26. The method according A.25, where the diol is injected in the form of a drug selected from the group consisting of a solution, dispersion, emulsion, finely powdered, gel, paste, aerosol, cream, foam, substrate coated granules and block.



 

Same patents:

FIELD: organic chemistry, nematocides.

SUBSTANCE: invention relates to compounds of the formula (I): wherein Ar1 and Ar2 mean independently of one another unsubstituted phenyl or mono- or multi-substituted phenyl with substitutes having independent of one another values and chosen from the group including halogen atom, (C1-C6)-alkyl or halo-(C1-C6)-alkyl; Q1 means -OCH2 or -C(O); Q2 means a direct bond or -C(O); R3 means hydrogen atom; R4, R5 and R6 mean independently of one another hydrogen atom or (C1-C6)-alkyl; W means O or S atom; a means 1, 2, 3 or 4; b means 0; n means 0 or 1. Also, method proposes a method for synthesis of compound of the formula (I) and carriers and/or dispersers also. Also, invention proposes using compound of the formula (I) for control of nematodes. Invention provides preparing derivatives of benzamidoacetonitrile used in control of nematodes.

EFFECT: improved preparing method, valuable properties of compounds.

10 cl, 2 tbl, 19 ex

FIELD: agriculture, herbicides.

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EFFECT: herbicide with decreased toxic action on sunflower.

FIELD: agriculture.

SUBSTANCE: invention relates to preparations obtained by pharmacopoeia method from overground and underground parts of calamus (Acorus calamus L.) for controlling of freshwater mollusk.

EFFECT: enhanced assortment of effective agents for controlling of freshwater mollusk.

6 ex

FIELD: agriculture.

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EFFECT: composition of reduced toxicity.

9 cl, 1 tbl

FIELD: organic chemistry, agriculture.

SUBSTANCE: invention relates to anthranylamide derivative selected from compound of formula I or N-oxides thereof, wherein R1 represents methyl, F, Cl, Br; R2 represents F, Cl, Br, I, CF3; R3 represents CF3, Cl, Br, OCH2CF3; R4a represents C1-C4-alkyl; R4b represents H, CH3; and R5 represents Cl, Br, and agriculturally acceptable salt thereof. Also disclosed are composition for pest controlling containing biologically effective amount of formula I and at least one additional component selected from group comprising surfactants, solid and liquid diluents; composition for invertebrate insect controlling containing biologically effective amount of formula I and at least one additional biologically active compound or agent. Also disclosed are method for insect controlling as well as intermediates such as benzoxazinone and parasolocarboxylic acid derivatives.

EFFECT: compounds with insecticide activity, useful in insect controlling.

20 cl, 16 tbl, 33 ex

FIELD: organic chemistry, agriculture.

SUBSTANCE: invention relates to ortho-substituted arylamides of formula I , wherein J represents phenyl ring or pyrazole ring each substituted with one or two substitutes independently selected from R5; K represents -NR1C(=A)- or -NR1SO2-; L represents -C(=B)NR2-, -SO2NR2- or -C(=B)-; A and B represent O; R1 and R2 represent H; R3 represents C1-C6-alkyl optionally substituted with one or more substitutes, independently selected from group containing CN, NO2, C1-C4-alkylsulfonyl and C2-C6-alkoxycarbonyl; each R4 independently represents C1-C6-alkyl, halogen or CN; each R5 independently represents C1-C6-alkyl, halogen or C1-C4-haloalkoxy or pyridinyl optionally substituted with one substitute independently selected from R9; wherein R9 represents halogen; n = 1-2; with the proviso, that when K represents -NR1C(=A)- L is not -C(=B)NR2-, and salts thereof, method for insect controlling by using abovementioned compounds. Intermediate for synthesis of target compounds having formula 2 also is disclosed.

EFFECT: compounds with insecticide activity, useful in insect controlling.

15 cl, 21 tbl, 9 ex

FIELD: chemistry of organophosphorus compounds, agriculture, pesticides.

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EFFECT: valuable agricultural properties of agent.

1 tbl, 2 ex

FIELD: protective agent for houseplants.

SUBSTANCE: claimed agent contains (mass %): dried calendula flowers as active ingredient 1.67-1.86; milk as solvent 95.35-96.25; sand sugar as adhesive agent 2.08-2.79.

EFFECT: protective agent of increased effectiveness.

1 tbl, 3 ex

FIELD: agriculture, fungicides.

SUBSTANCE: claimed composition contains two components as active ingredients in synergistically effective amount in combination with respective filler, wherein component 1 represents O-methyloxime of 2-[α-{[(α-methyl-3-fluoromethylbenzyl)imino]oxy7}ortho-tolyl]-glyoxylic acid methyl aster, and component II represents compound selected from group containing II1 4-(2,2-difluoro-1,3-(benzodioxol-4-yl)-pyrrol-3-carbonitrile (fludioxanyl); II2 4-(2,3-dichlorophenyl)-pyrrol-3-carbonitrile (phenpiclonyl); II3 1-methylcyclohexanecarboxylic acid (2,2-dichloro-4-hydroxyphenyl)-amide (phenhexamide); II4 2-{2-[6-(2-cyanophenoxy)-pyrimidine-4-yloxy]phenyl}-3-methoxyacrilic acid methyl ester (azoxystrobin); II5 methoxyimino-(2-ortho-tolyloxymethylphenyl)-acetic acid methyl ester (cresoxymemethyl). Method for controlling and preventing of plant diseases also is disclosed. Claimed method includes application of stricken plant parts with component I and component II on any order or simultaneously in synergistically effective amount.

EFFECT: fungicide of high activity.

3 cl, 6 tbl, 4 ex

FIELD: forestry and agriculture.

SUBSTANCE: claimed stimulator contains running waters from distillation of essence oils such as fir, spruce, pine, larch, ledum, and birch.

EFFECT: agent of increased effectiveness; enhanced assortment of plant growth stimulators.

2 cl, 2 tbl

FIELD: organic chemistry, nematocides.

SUBSTANCE: invention relates to compounds of the formula (I): wherein Ar1 and Ar2 mean independently of one another unsubstituted phenyl or mono- or multi-substituted phenyl with substitutes having independent of one another values and chosen from the group including halogen atom, (C1-C6)-alkyl or halo-(C1-C6)-alkyl; Q1 means -OCH2 or -C(O); Q2 means a direct bond or -C(O); R3 means hydrogen atom; R4, R5 and R6 mean independently of one another hydrogen atom or (C1-C6)-alkyl; W means O or S atom; a means 1, 2, 3 or 4; b means 0; n means 0 or 1. Also, method proposes a method for synthesis of compound of the formula (I) and carriers and/or dispersers also. Also, invention proposes using compound of the formula (I) for control of nematodes. Invention provides preparing derivatives of benzamidoacetonitrile used in control of nematodes.

EFFECT: improved preparing method, valuable properties of compounds.

10 cl, 2 tbl, 19 ex

FIELD: agriculture, herbicides.

SUBSTANCE: invention relates to agent for reducing of toxic action of hormonal herbicidal 2,4-dichlorophenoxyacetic acid on sunflower sprouts. Claimed agent contains 2-(2-furil)-1,3-dioxolane of formula I .

EFFECT: herbicide with decreased toxic action on sunflower.

FIELD: agriculture.

SUBSTANCE: invention relates to preparations obtained by pharmacopoeia method from overground and underground parts of calamus (Acorus calamus L.) for controlling of freshwater mollusk.

EFFECT: enhanced assortment of effective agents for controlling of freshwater mollusk.

6 ex

FIELD: agriculture.

SUBSTANCE: claimed composition contains a) one or more insecticide, in particular parathyroid: b) one or more solvents selected from group comprising aliphatic monocarboxylic acid esters, aromatic monocarboxylic acid esters, aromatic dicarboxylic acid esters, and tri-n-alkyl phosphates; c) emulsion system including one or more anionic surfactants and two or more nonionic surfactants, wherein one surfactant has HLB of 4-12; d) one or more film-forming agents/thickeners; and e) water. Method for insect pest controlling includes application of claimed composition onto insects or plants.

EFFECT: composition of reduced toxicity.

9 cl, 1 tbl

FIELD: organic chemistry, agriculture.

SUBSTANCE: invention relates to anthranylamide derivative selected from compound of formula I or N-oxides thereof, wherein R1 represents methyl, F, Cl, Br; R2 represents F, Cl, Br, I, CF3; R3 represents CF3, Cl, Br, OCH2CF3; R4a represents C1-C4-alkyl; R4b represents H, CH3; and R5 represents Cl, Br, and agriculturally acceptable salt thereof. Also disclosed are composition for pest controlling containing biologically effective amount of formula I and at least one additional component selected from group comprising surfactants, solid and liquid diluents; composition for invertebrate insect controlling containing biologically effective amount of formula I and at least one additional biologically active compound or agent. Also disclosed are method for insect controlling as well as intermediates such as benzoxazinone and parasolocarboxylic acid derivatives.

EFFECT: compounds with insecticide activity, useful in insect controlling.

20 cl, 16 tbl, 33 ex

FIELD: organic chemistry, agriculture.

SUBSTANCE: invention relates to ortho-substituted arylamides of formula I , wherein J represents phenyl ring or pyrazole ring each substituted with one or two substitutes independently selected from R5; K represents -NR1C(=A)- or -NR1SO2-; L represents -C(=B)NR2-, -SO2NR2- or -C(=B)-; A and B represent O; R1 and R2 represent H; R3 represents C1-C6-alkyl optionally substituted with one or more substitutes, independently selected from group containing CN, NO2, C1-C4-alkylsulfonyl and C2-C6-alkoxycarbonyl; each R4 independently represents C1-C6-alkyl, halogen or CN; each R5 independently represents C1-C6-alkyl, halogen or C1-C4-haloalkoxy or pyridinyl optionally substituted with one substitute independently selected from R9; wherein R9 represents halogen; n = 1-2; with the proviso, that when K represents -NR1C(=A)- L is not -C(=B)NR2-, and salts thereof, method for insect controlling by using abovementioned compounds. Intermediate for synthesis of target compounds having formula 2 also is disclosed.

EFFECT: compounds with insecticide activity, useful in insect controlling.

15 cl, 21 tbl, 9 ex

FIELD: chemistry of organophosphorus compounds, agriculture, pesticides.

SUBSTANCE: invention describes bis-(diethylammonium)-dihydrogen-1-hydroxyethyl-1,1diphosphonate monohydrate of the formula (I) showing properties of stimulator of growth o agricultural root crop plants. Invention provides enhancing productivity of root crops beet and carrot and expanding assortment of agents for this designation.

EFFECT: valuable agricultural properties of agent.

1 tbl, 2 ex

FIELD: protective agent for houseplants.

SUBSTANCE: claimed agent contains (mass %): dried calendula flowers as active ingredient 1.67-1.86; milk as solvent 95.35-96.25; sand sugar as adhesive agent 2.08-2.79.

EFFECT: protective agent of increased effectiveness.

1 tbl, 3 ex

FIELD: agriculture, fungicides.

SUBSTANCE: claimed composition contains two components as active ingredients in synergistically effective amount in combination with respective filler, wherein component 1 represents O-methyloxime of 2-[α-{[(α-methyl-3-fluoromethylbenzyl)imino]oxy7}ortho-tolyl]-glyoxylic acid methyl aster, and component II represents compound selected from group containing II1 4-(2,2-difluoro-1,3-(benzodioxol-4-yl)-pyrrol-3-carbonitrile (fludioxanyl); II2 4-(2,3-dichlorophenyl)-pyrrol-3-carbonitrile (phenpiclonyl); II3 1-methylcyclohexanecarboxylic acid (2,2-dichloro-4-hydroxyphenyl)-amide (phenhexamide); II4 2-{2-[6-(2-cyanophenoxy)-pyrimidine-4-yloxy]phenyl}-3-methoxyacrilic acid methyl ester (azoxystrobin); II5 methoxyimino-(2-ortho-tolyloxymethylphenyl)-acetic acid methyl ester (cresoxymemethyl). Method for controlling and preventing of plant diseases also is disclosed. Claimed method includes application of stricken plant parts with component I and component II on any order or simultaneously in synergistically effective amount.

EFFECT: fungicide of high activity.

3 cl, 6 tbl, 4 ex

FIELD: forestry and agriculture.

SUBSTANCE: claimed stimulator contains running waters from distillation of essence oils such as fir, spruce, pine, larch, ledum, and birch.

EFFECT: agent of increased effectiveness; enhanced assortment of plant growth stimulators.

2 cl, 2 tbl

FIELD: agriculture, in particular, means for killing of mice and rats.

SUBSTANCE: rodenticide composition contains active substance - anticoagulant, attractant, food base, and sodium citrate, said components being used in the following ratio, wt%: anticoagulant 0.005-0.02; sodium citrate 3-5; attractant 2-5; food base the balance. Warfarin, difenacin, ethylfenacin, isoindan may be used as anticoagulant. Sugar, non-refined vegetable oil, and dried milk may be used as attractant. Cereal grain and groats, and combined feed may be used as food base. Rodenticide may further contain food colorant used in an amount of 0.02-0.05 wt%, with methylene blue or brilliant green or indigo carmine being used as colorant.

EFFECT: increased activity of rodenticide composition.

6 cl, 22 ex

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