Oil-in-water emulsion insecticide composition

FIELD: agriculture.

SUBSTANCE: claimed composition contains a) one or more insecticide, in particular parathyroid: b) one or more solvents selected from group comprising aliphatic monocarboxylic acid esters, aromatic monocarboxylic acid esters, aromatic dicarboxylic acid esters, and tri-n-alkyl phosphates; c) emulsion system including one or more anionic surfactants and two or more nonionic surfactants, wherein one surfactant has HLB of 4-12; d) one or more film-forming agents/thickeners; and e) water. Method for insect pest controlling includes application of claimed composition onto insects or plants.

EFFECT: composition of reduced toxicity.

9 cl, 1 tbl

 

The present invention relates to liquid compositions of insecticides, particularly pyrethroids, in the form of emulsions of the type oil-in-water (EMW), the method of production of such EMW compositions and to their use for pest control.

Due to the vast damage that pests cause to agricultural crops, forests and textile materials and the like, and due to the role they play in the emergence and transmission of human diseases, animals and crops, pesticide use is still inevitable. Insecticides play an important role in integrated pest management and worldwide they are indispensable to ensure acceptable yields.

In particular, the pyrethroids (natural and synthetic) are an important class of lipophilic pesticides. The ability to destroy arthropods based on their strong influence on the sodium channels of nerve membranes arthropods.

The use of liquid compositions for application by spray is for consumers a convenient way to protect their crops from pests. Liquid products are easier to dose before entering into the water and are more easily atomized and dilute after pouring into the tank of the sprayer.

This, in particular, relates to a liquid insecticidal compositions, especially liquid compositions is the s, which as active substances contain one or more pyrethroids. Conventional liquid insecticide, in particular PYRETHROID compositions are mulgirigala concentrates (EC), which are usually based on aromatic hydrocarbon solvents such as xylene, etc.

In WO-A 90/09103 disclosed a PYRETHROID composition of type oil-in-water. In such compositions more acceptable from an environmental point of view, the product part of the organic solvent is replaced by water.

EMW convenient for consumers because, unlike EC, EMW composition to prepare the mixture, directly used for application by spraying, they already represent the emulsion and therefore they are easy to dilute. It should be clear that the manufacturing operations necessary to obtain stable compositions emws are very different and more complex than that used for the preparation of EC.

Although known EMW composition of pyrethroids already have very favorable characteristics, there still remains the possibility of improvement, such as improved Toxicological profile of such compositions.

Now unexpectedly discovered that, on the basis of esters of carboxylic acids, are used as solvents, it is possible to obtain the article is stable EMW composition, containing insecticide, in particular PYRETHROID, which have significantly reduced toxicity. In contrast to the compositions disclosed in WO-A 90/09103, for the compositions of the present invention does not require the use of aromatic hydrocarbons as solvents or auxiliary solvent (cosolvent).

In EP-A 0567368 disclosed EC containing pyrethroids, in which the aromatic hydrocarbon is replaced by a combination of one or more derivatives of biphenyl, a polar co-solvent and a vegetable oil that provides superior portability by inhalation. In WO-A 96/01047 disclosed containing PYRETHROID EK, characterized by improved tolerance when exposed to eye, as the organic solvent includes vegetable oil or other esters. However, these documents do not describe the composition type EMW.

In line with this, one of the objectives of the present invention is to provide an emulsion of the type oil-in-water containing:

a) one or more insecticides, particularly pyrethroids;

b) one or more solvents selected from the group comprising esters of aliphatic monocarboxylic acids, esters of aliphatic dicarboxylic acids, esters of aromatizes the x monocarboxylic acids, esters of aromatic dicarboxylic acids and tri-n-alkylphosphine;

c) emulsifying system containing one or more anionic surfactants and two or more nonionic surfactants, one of which has value products HLB (hydrophilic-lipophilic balance)equal to from 4 to 12, and one of which has value products HLB equal to from 12 to 20;

d) one or more film-forming reagents/thickeners;

e) water.

EMW corresponding to the present invention have significantly weakened characteristics acute toxicity; in many cases they do not belong to the group of substances with acute oral toxicity. In particular, this means that acute oral LD50for rats is > 2000 mg/(kg body mass) and that the composition does not irritate any skin or eyes.

At the same time, these compositions have excellent biological efficiency and all the other benefits customary for EMW, such as ease of use and reduced content of aromatic solvents.

The term "EMW composition" means undiluted composition.

Compositions corresponding to the present invention contain one or more, p is edocfile 1 or 2, more preferably 1 insecticide selected from the group of natural or synthetic pyrethroids.

Examples suitable for use of insecticides, in particular, are:

1) from the group of phosphorus compounds:

Arafat, azamethiphos, azinphos-ethyl, azinphos-methyl, bromophos, bromophos-ethyl, cadusafos (F-67825), chlorethoxyfos, Chlorfenvinphos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, demeton, demeton-S-methyl, demeton-S-methylsulfone, dialifos, diazinon, dichlorvos, dicrotophos, dimethoate, disulfoton, EPN, ethion, ethoprophos, etrimfos, Rampur, fenamiphos, fenitrothion, fensulfothion, fenthion, fonofos, formation, fosthiazate (ASC-66824), heptenophos, isazofos, isocial, isoxathion, Malathion, methacrifos, metamidophos, mitigation, salicion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion, parathion-methyl, pentat, Fort, fosalan, phosfolan, fastcars (BAS-301), phosmet, phosphamidon, phoxim, pirimiphos, pirimiphos-ethyl, pirimiphos-methyl, profenofos, propafol, propetamphos, prothiofos, pyraclofos, peridinin, quinalphos, sulprofos, temephos, terbufos, tebupirimfos, tetrachlorvinphos, thiometon, triazophos, trichlorfon, vamidothion;

2) from the group of carbamates:

alankar (CA-135), aldicarb, 2-second-butylphenylmethyl (VRMS), carbaryl, carbofuran, carbosulfan, cloethocarb, benfuracarb, ethiofencarb, furathiocarb, HCN-801, isop ocarb, methomyl, 5-methyl-m-kumanivtsi-(methyl)-carbamate, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, 1-methylthio-(ethylidene)-N-methyl-N-(morpholinothio)-carbamate (UC 51717), triazamate;

3) from the group of pyrethroids:

acrinathrin, allethrin, alphamethrin, 5-benzyl-3-furylmethyl (E)-(1R)-CIS-2,2-dimethyl-3-(2-oxathiolan-3-ylidenemethyl)-cyclopropanecarboxylate, beta-cyfluthrin, beta-cypermethrin, bioallethrin, bioallethrin ((S)-cyclopentenyl isomer), bioresmethrin, bifenthrin, (RS)-1-cyano-1-(6-phenoxy-2-pyridyl)-methyl (1RS)-TRANS-3-(4-tert-butylphenyl)-2,2-dimethylcyclopropanecarboxylate (NCl 85193), cicloprofen, cyfluthrin, cigalotrin, Caitrin, cypermethrin, cyphenothrin, deltamethrin, empenthrin, esfenvalerate, fenfluthrin, fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate (D-isomer), imiprothrin (S-41311), lambda cigalotrin, permethrin, phenothrin ((R)-isomer), prallethrin, pyrethrins (natural products), resmethrin, tefluthrin, tetramethrin, theta-cypermethrin (TD-2344), tralomethrin, transfluthrin, Zeta-cypermethrin (F-56701);

4) from the group amidino:

amitraz, Chlordimeform;

5) from the group of compounds of tin:

cyhexatin, fenbutatin;

6) others:

the abamectin, ABG-9008, acetamiprid, Anagrapha falcitera, AKD-1022, AKD-3059, ANS-118, Bacillus thuringiensis, Beauveria bassiana, bensultap, bifenazate (D-2341), Bina-pakil, BJL-932, bromopropylate, BTG-504, BTG-505, buprofezin, camphechlor, cartap, chlorbenzyl is, chlorfenapyr, chlorfluazuron, 2-(4-chlorophenyl)-4,5-diphenylthiophene (UBI-T 930), chlorphenesin, chromafenozide (ANS-118), CG-216, CG-217, CG-234, A-184699, (2-naphthylmethyl)-cyclopropanecarboxylate (Ro12-0470), cyromazine, dialogen (thiamethoxam), diafenthiuron, ethyl-N-3,5-dichloro-4-(1,1,2,3,3,3-hexamer-1 propyloxy)-phenyl)-carbarnoyl)-2-chlorobenzoyloxy, DDT, di-syrups, diflubenzuron, N-(2,3-dihydro-3-methyl-1,3-thiazol-2-ilidene)-2,4-xylidine, dinobuton, dinocap, giovanola, DPX-062, amaneciendo (MK-244), endosulfan, ethiprole (sulfation), etofenprox, etoxazole (YI-5301), fenazaquin, fenoxycarb, fipronil, fluazuron, flumet (Florentin, SZI-121), 2-fluoro-5-(4-(4-ethoxyphenyl)-4-methyl-1-pentyl)-diphenyl ether (MTI 800), viruses granules and nuclear polyhedrosis, fenpyroximate, benthiocarb, flibanserin, flucycloxuron, flufenoxuron, flavandiols (ICI-A5683), propoxyphen, gamma-HCH, halogenated (RH-0345), halftracks (MTI-732), hexaflumuron (DE-473), hexythiazox, HOI-9004, hydramethylnon (AC 217300), lufenuron, Imidacloprid, indoxacarb (DPX-MR), kanamit (AKD-2023), M-020, MTI-446, ivermectin, M-020, methoxyfenozide (Empire state building, RH-2485), milbemectin, NC-196, neergard, nitenpyram (TI-304), 2-nitro methyl-4,5-dihydro-6N-thiazin (DS 52618), 2-nitro methyl-3,4-dihydrodiol (SD 35651), 2-nitromethylene-1,2-diazinon-3-ylcarbamate (WL 108477), pyriproxyfen (S-71639), NC-196, NC-1111, NNI-9768, novaluron (MCW-275), OK-9701, OK-9601, OK-9602, propargite, pymetrozine, pyridaben, pyrimidifen (SU-8801),RH-0345, RH-2485, RYI-210, S 1283, S-1833, SB7242, SI-8601, selflove, Solomatin (CG-177), spinosad, SU-9118, tebufenozide, tebufenpyrad (MK-239), teflubenzuron, tetradifon, tetrasul, thiacloprid, thiocyclam, TI-435, tolpinrud (OMI-88), triazamate (RH-7988), triflumuron, verboten, vertalec (mycotal), YI-5301.

A preferred group of insecticides are natural or synthetic pyrethroids, for example:

acrinathrin, allethrin, alphamethrin, 5-benzyl-3-furylmethyl (E)-(1R)-CIS-2,2-dimethyl-3-(2-oxathiolan-3-ylidenemethyl)-cyclopropanecarboxylate, beta-cyfluthrin, beta-cypermethrin, bioallethrin, bioallethrin ((S)-cyclopentenyl isomer), bioresmethrin, bifenthrin, (RS)-1-cyano-1-(6-phenoxy-2-pyridyl)-methyl(1RS)-TRANS-3-(4-tert-butylphenyl)-2,2-dimethylcyclopropanecarboxylate (NCI 85193), cicloprofen, cyfluthrin, cigalotrin, Caitrin, cypermethrin, cyphenothrin, deltamethrin, empenthrin, esfenvalerate, fenfluthrin, fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate (D-isomer), imiprothrin (S-41311), lambda cigalotrin, permethrin, phenothrin ((R)-isomer), prallethrin, pyrethrins (natural products), resmethrin, tefluthrin, tetramethrin, theta-cypermethrin (TD-2344), tralomethrin, transfluthrin and Zeta-cypermethrin (F-56701).

Preferred are acrinathrin, bioallethrin, (S)-bioallethrin and deltamethrin. Especially preferred are acrinathrin and/or deltamethrin, even more preferred is is deltamethrin.

It is also preferable to use a mixture of one or more pyrethroids and one or more naperedodni insecticides, such as pipoly, nitromethylene, carbamates.

From naperedodni insecticides especially preferred are pipoly, acetamiprid and primicarb.

The concentration of the active substance (s) is usually from 0.05 to 200 g/l, preferably from 0.1 to 50 g/l, particularly preferably from 1 to 25 g/L.

Pyrethroids and other listed insecticides are well known and generally commercially available. They are described, for example, guide The Pesticide Manual, 11thed., British Crop Protection Council, Farnham 1997.

Esters, used as the organic solvent, selected from the group comprising esters of aliphatic monocarboxylic acids, esters of aliphatic di - and tricarboxylic acids, esters of aromatic monocarboxylic acids, esters of aromatic di - and tricarboxylic acids and tri-n-alkylphosphine, preferably tri-n-(C1-C6-alkylphosphate, such as tri-n-butylphosphate.

It is preferable to choose them from the group comprising esters of aliphatic monocarboxylic acids, esters of aliphatic di - and tricarboxylic acids and esters of aromatic monocarboxylic acids.

An example is mi esters of aliphatic monocarboxylic acids are aliphatic such as methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, n-pentalogy, isopentylamine, neopentylene, n-hexyl, isohexyl, n-p, isolately, n-oktilovom, ethylhexyloxy, n-nonlevy and econonomy) and aromatic (such as benzyl) esters of fatty acids, such as acetic acid (such as ethyl acetate and n-butyl acetate), hexanoic acid, Caprylic acid, capric acid, a mixture of Caprylic and capric acid, lauric acid, myristic acid, a mixture of lauric and myristic acids, palmitic acid, stearic acid, a mixture of palmitic and stearic acids, Mirandolina acid, palmitoleic acid, oleic acid, linoleic acid and linolenic acid, and carboxylic acids containing additional functional groups, such as lactic acid (such as ethyllactate, butylacetate, Ethylhexylglycerin and 1-methoxy-2-propyl).

A preferred group of esters of aliphatic monocarboxylic acids are vegetable oils and animal fats. When used in the present invention, the term "vegetable oil" means oil extracted from oilseeds, such as rapeseed oil, soybean oil, palm oil, sunflower oil, cottonseed oil, corn oil, linseed oil, coconut oil is, oil from the seeds of thistles and castor oil. When used in the present invention, the term "animal fat means the fat obtained from animal fat breeds, such as butter. Other examples of esters of monocarboxylic acids are products of interesterification of these oils, such as alkalemia esters such as methyl esters of the acids of rapeseed oil, such as Radia 7961 (Fina Chemicals, Belgium), or ethyl esters of the acids of rapeseed oil.

Preferred vegetable oils are esters (C10-C22)fatty acids, more preferable - (C12-C20)fatty acids. These esters (C10-C22)-fatty acids are, for example, esters of unsaturated or saturated (C10-C22)-fatty acids, in particular with an even number of carbon atoms, for example, CIS-erucic acid, sorokovoy acid, lauric acid, palmitic acid, myristic acid, particularly With18fatty acids such as stearic acid, linoleic acid or linolenic acid.

Examples of esters (C10-C22)-fatty acids are esters that get by the reaction of glycerol or glycol with (C10-C22)fatty acids and which contains, for example, oils, oilseeds, and (C -C20)-alkyl esters (C10-C22)-fatty acids, which can be obtained, for example, by transesterification of the above esters of glycerol or glycol with (C10-C22)-fatty acids with (C1-C20)-alcohols (such as methanol, ethanol, propanol or butanol). The transesterification may be carried out by methods well known in the art, described, for example, in the management of Römps Chemie Lexikon, 9thedition, Volume 2, page 1343, Thieme Verlag, Stuttgart.

Preferred (C1-C20)-alkyl esters (C10-C22)fatty acids are the methyl esters, ethyl esters, n-propyl esters, isopropyl esters, n-butyl esters, isobutyl esters, n-pentalonia esters, isopentylamine esters, neopentyl esters, n-hexyl esters, isohexyl esters, n-p esters, isoheptane esters, n-oktilovom esters, 2-ethylhexylamine esters, n-Monrovia esters, izonanelwa esters and dodecylamine esters. As esters of glycerol and glycol with (C10-C22)-fatty acids are preferred pure or mixed ethers of glycerol or glycol with (C10-C22)fatty KIS is otami, especially with fatty acids with an even number of carbon atoms, such as CIS-erucic acid, ISO-erucic acid, lauric acid, palmitic acid, myristic acid, in particular, C18fatty acids such as stearic acid, linoleic acid and linolenic acid.

EMW composition corresponding to the present invention may contain vegetable oils in the form of commercially available auxiliary compositions of oils, for example on the basis of rapeseed oil, such as Hasten®(Victorian Chemical Company, Australia, the main component of the ethyl esters of the acids of rapeseed oil), Actirob®B (Novance, France, the main component of the methyl esters of the acids of rapeseed oil), Rako-Binol®(Bayer AG, Germany, the main component in rapeseed oil), Renol®(Stefes, Germany, the main component of the methyl esters of the acids of rapeseed oil) and Stefes Mero®(Stefes, Germany, the main component of the methyl esters of the acids of rapeseed oil).

Examples of esters of aromatic monocarboxylic acids include esters of benzoic acid (such as n-butylbenzoate, benzyl benzoate, delventhal, dodecylbenzene, hexylbenzoate, isostearate, methylbenzoate, octadecylphenol, (C12-C15-alkylbenzoic) or salicylic acid.

Examples of esters of aliphatic di - and tricarboxylic to the slot include esters of maleic acid (methyl, ethyl), diesters and treatery adipic acid (such as diisopropylamide (such as Crodamol®DA (Croda Oleochemicals, UK), diisobutylamine), citric acid (such as tributyltin, acetyltributyl), glutaric acid and succinic acid (such as esters of dibasic acid: a mixture of methyl esters of adipic, glutaric and succinic acids) and sabatinovka acid (such as n-octylbenzene).

Examples of esters of aromatic dicarboxylic acids include phthalates (such as dimethylphthalate, diethylphthalate, dibutyl phthalate or diisononylphthalate).

Along with using as solvent one complex ester is also preferable to use two or more.

It may be useful, particularly if the active substance is not very soluble in the used solvent ether complex, to include one or more polar co-solvents. When used in the present invention, the term "polar co-solvents" means the co-solvents that are completely or partially soluble in water (for example, from 0.1 to 100%). Usually choose a co-solvent with low toxicity and low ability to cause irritation to skin and eyes.

Examples of polar co-solvents are ketones (such as cyclohexane is, the acetophenone, methyl-n-amylketone and 2 heptane), alcohols (such as benzyl alcohol), alkylamide (such as N,N-dimethylacetamide), alkylpyridine (such as N-organic N-octylpyrimidine, N-dodecylmercaptan and N-hydroxy-2-ethylpyrrolidin), diallylsulfide (such as dimethylsulfoxide), ethers (such as anisole and 1-methoxy-2-propanol) or urea derivatives (such as dimethylpropyleneurea).

Preferred polar co-solvents are cyclohexanone (solubility in water: 8% at room temperature), 2-heptanol, benzyl alcohol (solubility in water: 4% at room temperature), N,N-dimethylacetamide (solubility in water: soluble no data), N-organic (solubility in water: 100% at room temperature), dimethylsulfoxide (solubility in water: 100% at room temperature) and 1-methoxy-2-propanol (solubility in water: 100% at room temperature), especially in combination with deltamethrin as the active substance.

The content of the polar co-solvent is usually from 1 to 25 wt.%, preferably from 2 to 20 wt.%, more preferably from 8 to 20 wt.%. The content of the co-solvent should usually choose as low as possible but high enough to increase the solubility of the active substance so as to provide the necessary content activegeodiv in the finished product and to avoid crystallization during dilution before application.

In a preferred embodiment, the composition corresponding to the present invention, does not contain any other solvent addition of ester (esters)used as a main solvent, and an optional polar co-solvent, i.e. the part of the song, which solvent contains mainly ester component and optionally one or more polar cosolvent.

Compositions additionally contain mulierum system comprising one or more anionic emulsifiers and two or more non-ionic emulsifiers.

Examples of anionic emulsifiers are the phosphates and sulphates of polatok-sidirovanii (preferably from 2 to 30) of fatty alcohols (preferably from C6to C22), such as ethoxylated phosphate (2 EA)-olejowego alcohol (EO means ethylenoxide group) (for example, Empiphos®O3D, Albright &Wilson, UK), ethoxylated phosphates olejowego alcohol (for example, Crodafos®N serie, Croda Oleochemicals, UK), ethoxylated phosphates (2-10 EA)-Zeta/stearyl alcohol (for example, Crodafos®CS serie, Croda Oleochemicals, UK), ethoxylated phosphates (4-6 EA)-tridecylalcohol alcohol (for example, Emphos®PS serie, CK Witco, USA), ethoxylated phosphates, fatty alcohols (for example, Crafol®AR serie Henkel Iberica, Spain), ethoxylated phosphates (3-6 EO)-fatty alcohols (for example, Rhodafac®serie, Rhodia Chimie, France), acids obtained by saponification of complex organic phosphates (e.g., Beycostat®serie, Ceca S.A., France), phosphates polyethoxysiloxane (from 8 to 25 EO)-kilfenora (such as polyethoxysiloxane di-and cristianfmemoli) (for example, Soprophor 3D33, Rhodia Chimie, France), sulfates polyethoxysiloxane of kilfenora (such as polyethoxysiloxane di - and cristianfmemoli) (for example, Soprophor DSS/7, Soprophor 4D384, Rhodia Chimie, France), inorganic alkylbenzenesulfonate (such as dodecylbenzenesulfonate calcium and inorganic salts of polybasic carboxylic acids, such as sodium and potassium salts, which are preferred.

Nonionic emulsifiers are usually chosen from the class polyethoxylated ALKYLPHENOLS. Examples of suitable nonionic emulsifiers are polyethoxysiloxane (from 30 to 40 EO)-castor oil, polyethoxysiloxane (from 6 to 20 EO)-(C8to C22)-fatty alcohols, polyethoxysiloxane (from 8 to 25 EO)-kilfenora (such as polyethoxysiloxane di - and cristianfmemoli), politicologie ethers tridecylalcohol alcohol (such as ethoxylated (6 EA)-tridecylamine alcohol: Genapol®X-060, Clariant, Germany), polyalkoxysiloxanes alkalemia esters (such as polyalkoxysiloxanes butyl ether: Witconol#x000AE; NS 500 K, CK Witco, USA), block copolymers of ethylene oxide with propylene oxide (molecular weight in the range from 4000 to 20000, preferably in the range from 6500 to 15000).

Usually use a combination of anionic emulsifier with a combination of two or more, preferably two, nonionic emulsifiers, in which one nonionic emulsifier has the products HLB value equal to from 4 to 12, preferably from 8 to 12, and one nonionic emulsifier has the products HLB value equal to from 12 to 20, preferably from 14 to 18. This will provide a particularly good physico-chemical characteristics of the composition EMW at high and low temperatures.

Index products HLB (hydrophilic-lipophilic balance) is an empirical value entered W.C.Griffin (J. Soc. Cosmetic Chemists, 1, 311 (1949)), which characterizes the amphiphilic nature of the emulsifying reagents (particularly non-ionic surfactants). Less hydrophilic surfactant correspond to smaller values of products HLB index.

The composition typically contains from 0.01 to 20 wt.%, preferably from 0.1 to 10 wt.% combinations of anionic and nonionic emulsifiers, more preferably, a combination ranged from 0.01 to 10 wt.%, more preferably from 0.1 to 3 wt.% anionic emulsifier and from 0.01 to 15 wt.%, more before occhialino from 0.1 to 7 wt.% two or more nonionic emulsifiers.

The composition additionally includes one or more film-forming reagents/thickeners. Examples of suitable film-forming reagents/thickeners are thermoplastic resins, such as polyvinylpyrrolidone (such as®Luviskol K 90, BASF AG, Germany, with equal from 88 to 96 index K, which characterizes the viscosity of an aqueous solution containing 1 wt.% this brand polyvinylpyrrolidone), polyvinyl alcohol obtained by partial hydrolysis of polyvinyl acetate (such as products Mowiol characterized by the viscosity of an aqueous solution containing 4 wt.% product Mowiol, Clariant, Germany) and copolymers of vinyl pyrrolidone/vinyl acetate (such as Agrimer VA 6, ISP, USA, which contains 60% vinylpyrrolidone).

The use of appropriate emulsifiers in combination with film-forming agents/thickeners is a particularly useful way of ensuring high stability of the composition.

Film-forming reagents/thickeners are usually added in amounts of from 0.1 to 5.0 wt.%, preferably from 0.5 to 3.0 wt.%.

The composition typically contains from 5 to 99 wt.%, preferably from 10 to 85 wt.%, more preferably from 45 to 65 wt.% water.

The composition optionally contains additional additives or auxiliary substances, preferably antifreeze, stabilizing substances, the anti-Christ. Osinovaya and panagsama substances, preservatives, colorants and/or products, masking the smell.

Examples of suitable antifreeze is ethylene glycol, monopropellant, glycerin, hexyleneglycol, 1-methoxy-2-propanol, cyclohexanol, and preferably monopropellant.

They do not necessarily add to the number, preferably equal to from 1 to 30 wt.%, more preferably from 5 to 15 wt.%.

Stabilizing substances, which are not necessarily added in the composition, are acids, preferably organic acids such as dodecylbenzenesulfonic acid, acetic acid, propionic acid and citric acid, preferably citric acid, and antioxidants such as equivalent (OSH), butylhydroxyanisole (BHA), preferably equivalent.

Stabilizing substances are not necessarily added in amount equal to from 0.01 to 2 wt.%, preferably from 0.1 to 1 wt.%.

Preferred protivovspenivayushchie and panagsama substances based on silicone, particularly preferred are aqueous emulsion of dialkylammonium, sold under the name Rhodorsil®426R by the company Rhodia Chimie France, series SE Wacker production Wacker, Germany, and the mixture dialkylammonium in the form of oil, sold under the name Rhodorsil®416 by the company Rhodia Chimie France, Wacker 184 and Wacker SL production company Wacker, Germany.

Protivovspenivayushchie/panagsama substances optionally added in amounts equal to from 0.01 to 2 wt.%, preferably from 0.1 to 1.5 wt.%.

Optional add conventional preservatives, such as, for example, derivatives of benzoic acid, sorbic acid, formaldehyde, in particular, the combination of methylparahydroxybenzoate (such as Preserval®M (Laserson & Sabetay, France)with propilparagidroksibenzoat (such as Preserval®P (Laserson & Sabetay, France)), usually in a quantity of from 0.1 to 1.0 wt.%, preferably from 0.2 to 0.5 wt.%.

Other preferred optional additives are coloring agents such as Vitasyn®Patentbiau (Clariant, Germany) and products, masking the smell, such as a mixture of numerous natural and synthetic perfumes such as Perfume®TM 4242 (Technicoflor, France).

They do not necessarily add to the number equal to from 0.01 to 1 wt.%, preferably from 0.1 to 0.5 wt.% for colorants and from 0.02 to 2 wt.%, preferably from 0.1 to 1 wt.% for products that mask the smell.

Another object of the present invention is the provision of a method of preparation of insecticidal, in particular PYRETHROID described above emulsion of the type oil-in-water (EMW), which is a three-stage method:

A. preparation of the organic phase is, including the dissolution of insecticide, in particular PYRETHROID, is active substance (s) in one or more organic solvents and, optionally, a polar co-solvent (polar cosolvent) and further addition of emulsifiers and, optionally, stabilizing agents and/or preservatives, preferably using a mixer, such as a paddle mixer.

To facilitate solubilization of hydrophilic emulsifier include optional stage heating (temperatures reaching 30°).

C. Preparation of the aqueous phase, comprising mixing water with optional antifreeze using, for example, rotor-stator ultradispersed device (CDN) with the subsequent addition of film-forming reagent/thickener. To prevent the formation of lumps useful to sprinkle powdered polymer (film-forming agent) on the surface of the aqueous phase.

Using a mixer, such as a paddle mixer, in the above liquid phase at room temperature, you can add the following optional components:

- the dye,

products, masking the smell and

- protivovspenivayushchie substances.

The operation of the mixing continued until a homogeneous aqueous phase.

C. Third stage VC is uchet preparation ready PYRETHROID insecticidal emulsion of the type oil-in-water (EMW) by dispersion of water or aqueous phase, obtained at stage b, the organic phase obtained in stage A, preferably at room temperature and at high shear force using, for example, mixer, which creates high shear stress, such as rotor-stator mixer, produced by companies such as Silverson (UK) and IKA (Germany). It is preferable first to combine these two phases without any mixing. Then this mixture is exposed to large shear forces (maximum T=35°).

Preferably, the insecticide, in particular, a PYRETHROID, the emulsion of the type oil-in-water (EMW), obtained with the help of this method, had the following characteristics:

- when measuring with an instrument Brookfield, equipped with a module LV2, rotating at 30 and 60 rpm, the viscosity of the composition of the electric wave corresponding to the present invention is in the range from 50 to 150 MPa·C. the Measurements were carried out at a temperature equal to 25±5°C;

- spontaneous formation of a homogeneous emulsion upon dilution of the composition with water (when mixing from 0.1 to 5 wt./about. % composition of water in the cylinder 100 ml) is extremely strong due to the low viscosity;

- when measured with a laser particle size analyzer, such as equipment sold companies and Cilas Malvern distribution of droplets in size, characterized by a mean diameter varies in the range from 0.3 to 0.8 μm, and 80% of the droplets have a diameter of less than 1 micron.

Preferably, the composition (compositions) of the electric wave corresponding to the present invention was stable for at least 2 weeks at 54°C, 6 weeks at 50°and -10°and at least two years at room temperature.

The present invention also relates to a method of combating pests, such as harmful arthropods, such as insects and mites which comprises applying an effective amount of the above insecticidal, in particular PYRETHROID compositions of the type oil-in-water (EMW), preferably in the form of an aqueous solution, these pests or plants, soil, surface, etc. contaminated by them, to insecticidal, in particular PYRETHROID compositions of the type oil-in-water (EMW) for plant protection, fight against other pests, such as the fight against vector control, use at home, for the treatment of domestic animals, etc. and in veterinary medicine.

The composition corresponding to the present invention, simply put by dilution of the emulsions of the type oil-in-water (EMW) the required amount of water, intermittent stirring of the mixture and its application to plants, soil, surface, etc.

The present invention updat is further illustrated by the examples, listed in table I and do not limit the present invention.

Table
(The concentrations of all components are expressed in g/l)Example No.
Component (trade name)Component (function)1234567891011
Deltamethrin (98,5%)The active ingredient5,115,215,215,215,215,215,215,215,215,2
FipronilThe active ingredient15,0
DiethylphthalateSolvent80,080,0120,0120,0120,0
Crodamol DA Solventat 149.5at 149.560,060,0162,7162,760,060,0
n-ButylbenzoateSolvent107,8
The benzyl benzoateSolvent120,0
Methyl esters of the acids of rapeseed oilSolvent300,0
Tributyl phosphateSolvent150,0
Cyclohexanoneco-solvent 130,0130,0120,0120,0120,0120,0120,0120,0120,0
Heptane-2-heThe co-solvent90,0
The sulfoxideThe co-solvent60,0
Empiphos O3DAnionic emulsifier10,010,05,010,010,010,010,010,010,010,010,0
Genapol X-060Nonionic emulsifier20,035,0of 17.5of 17.5of 17.5of 17.5of 17.5of 17.5of 17.5of 17.5of 17.0
Witconol NS 500 ToNonionic emulsifier40,035,0 of 17.5of 17.5of 17.5of 17.5of 17.5of 17.5of 17.5of 17.5of 17.0
Luviskol K 90Film-forming substance10,020,015,015,015,015,015,015,015,015,05,0
Rhodorsil416Protivovspenivayushchie substance0,20,20,20,20,20,20,20,20,2
Rhodorsil 426 RProtivovspenivayushchie substance0,20,20,20,20,20,20,20,20,2
Preserval PPreservative0,10,10,10,10,10,10,10,10,2
Preserval MPreservative0,10,10,10,10,10,10.1/td> 0,10,2
Citric acidStabilizer0,20,20,2
Perfume TM 4242Perfume0,5
Vitasyn PatentblauThe dye0,2
Propylene glycolAntifreeze80,0120,0120,0120,0120,0120,0120,0120,0100,0
Water,1 l1 l1 l1 l1 l1 l1 l1 l1 l1 l1 l

1. Insecticidal EMU is sionna composition of type oil-in-water, contains

a) one or more insecticides, particularly pyrethroids;

b) one or more solvents selected from the group comprising esters of aliphatic monocarboxylic acids, esters of aliphatic dicarboxylic acids, esters of aromatic monocarboxylic acids, esters of aromatic dicarboxylic acids and tri-n-alkylphosphine;

c) emulsifying system containing one or more anionic surfactants and two or more nonionic surfactants, one of which has the value hydrophilic-lipophilic balance of from 4 to 12, and one of which has the value hydrophilic-lipophilic balance of from 12 to 20;

d) one or more film-forming reagents/thickeners; and

e) water.

2. Insecticidal composition according to claim 1, in which the insecticide is a PYRETHROID.

3. Insecticidal composition according to claim 2, in which the PYRETHROID is deltamethrin.

4. Insecticidal composition according to claim 1, containing a polar co-solvent.

5. Insecticidal composition according to claim 1, optionally containing additives and/or auxiliary substances selected from the group including antifreeze, stabilizing substances which, protivovspenivayushchie/panagsama substances, preservatives, colorants and products, masking the smell.

6. Insecticidal composition according to one of claims 1 to 5, containing from 0.05 to 200 g/l of active substances (active substances).

7. Method of controlling insects comprising applying an aqueous solution of insecticidal emulsion compositions of the type oil-in-water according to claim 1 to the insects or plants or other locations, infected or frequented by insects.

8. The method according to claim 7, in which the insecticide is a PYRETHROID.

9. The method according to claim 8, in which the PYRETHROID is deltamethrin.



 

Same patents:

FIELD: organic chemistry, agriculture.

SUBSTANCE: invention relates to anthranylamide derivative selected from compound of formula I or N-oxides thereof, wherein R1 represents methyl, F, Cl, Br; R2 represents F, Cl, Br, I, CF3; R3 represents CF3, Cl, Br, OCH2CF3; R4a represents C1-C4-alkyl; R4b represents H, CH3; and R5 represents Cl, Br, and agriculturally acceptable salt thereof. Also disclosed are composition for pest controlling containing biologically effective amount of formula I and at least one additional component selected from group comprising surfactants, solid and liquid diluents; composition for invertebrate insect controlling containing biologically effective amount of formula I and at least one additional biologically active compound or agent. Also disclosed are method for insect controlling as well as intermediates such as benzoxazinone and parasolocarboxylic acid derivatives.

EFFECT: compounds with insecticide activity, useful in insect controlling.

20 cl, 16 tbl, 33 ex

FIELD: organic chemistry, agriculture.

SUBSTANCE: invention relates to ortho-substituted arylamides of formula I , wherein J represents phenyl ring or pyrazole ring each substituted with one or two substitutes independently selected from R5; K represents -NR1C(=A)- or -NR1SO2-; L represents -C(=B)NR2-, -SO2NR2- or -C(=B)-; A and B represent O; R1 and R2 represent H; R3 represents C1-C6-alkyl optionally substituted with one or more substitutes, independently selected from group containing CN, NO2, C1-C4-alkylsulfonyl and C2-C6-alkoxycarbonyl; each R4 independently represents C1-C6-alkyl, halogen or CN; each R5 independently represents C1-C6-alkyl, halogen or C1-C4-haloalkoxy or pyridinyl optionally substituted with one substitute independently selected from R9; wherein R9 represents halogen; n = 1-2; with the proviso, that when K represents -NR1C(=A)- L is not -C(=B)NR2-, and salts thereof, method for insect controlling by using abovementioned compounds. Intermediate for synthesis of target compounds having formula 2 also is disclosed.

EFFECT: compounds with insecticide activity, useful in insect controlling.

15 cl, 21 tbl, 9 ex

FIELD: chemistry of organophosphorus compounds, agriculture, pesticides.

SUBSTANCE: invention describes bis-(diethylammonium)-dihydrogen-1-hydroxyethyl-1,1diphosphonate monohydrate of the formula (I) showing properties of stimulator of growth o agricultural root crop plants. Invention provides enhancing productivity of root crops beet and carrot and expanding assortment of agents for this designation.

EFFECT: valuable agricultural properties of agent.

1 tbl, 2 ex

FIELD: protective agent for houseplants.

SUBSTANCE: claimed agent contains (mass %): dried calendula flowers as active ingredient 1.67-1.86; milk as solvent 95.35-96.25; sand sugar as adhesive agent 2.08-2.79.

EFFECT: protective agent of increased effectiveness.

1 tbl, 3 ex

FIELD: agriculture, fungicides.

SUBSTANCE: claimed composition contains two components as active ingredients in synergistically effective amount in combination with respective filler, wherein component 1 represents O-methyloxime of 2-[α-{[(α-methyl-3-fluoromethylbenzyl)imino]oxy7}ortho-tolyl]-glyoxylic acid methyl aster, and component II represents compound selected from group containing II1 4-(2,2-difluoro-1,3-(benzodioxol-4-yl)-pyrrol-3-carbonitrile (fludioxanyl); II2 4-(2,3-dichlorophenyl)-pyrrol-3-carbonitrile (phenpiclonyl); II3 1-methylcyclohexanecarboxylic acid (2,2-dichloro-4-hydroxyphenyl)-amide (phenhexamide); II4 2-{2-[6-(2-cyanophenoxy)-pyrimidine-4-yloxy]phenyl}-3-methoxyacrilic acid methyl ester (azoxystrobin); II5 methoxyimino-(2-ortho-tolyloxymethylphenyl)-acetic acid methyl ester (cresoxymemethyl). Method for controlling and preventing of plant diseases also is disclosed. Claimed method includes application of stricken plant parts with component I and component II on any order or simultaneously in synergistically effective amount.

EFFECT: fungicide of high activity.

3 cl, 6 tbl, 4 ex

FIELD: forestry and agriculture.

SUBSTANCE: claimed stimulator contains running waters from distillation of essence oils such as fir, spruce, pine, larch, ledum, and birch.

EFFECT: agent of increased effectiveness; enhanced assortment of plant growth stimulators.

2 cl, 2 tbl

FIELD: organic chemistry, veterinary science.

SUBSTANCE: invention describes using aminoacetonitrile compounds of the formula (I): wherein Ar1 and Ar2 mean independently of one another unsubstituted phenyl or phenyl substituted with halide; Q means -C(R1)(R2) wherein R1 and R2 or independently of one another mean hydrogen atom, or in common with carbon atom to which they are bound form (C2-C6)-alkylene; d = 1; R3 means hydrogen atom, (C1-C6)-alkyl or (C2-C6)-alkynyl; each among R4, R5, R6, R7 and R8 means independently of one another hydrogen atom, (C1-C6)-alkyl or (C3-C6)-cycloalkyl; or R4 and R5 mean in common (C2-C6)-alkylene; W means oxygen atom; a and b mean independently of one another 0 or 1, and optionally of their enantiomers in control of endoparasitic pests in warm-blooded productive cattle and domestic animals. Also, the invention describes the composition and a method for control of endoparasitic pests. Above said compounds are used for control of endoparasites, especially, helminthes in warm-blooded productive cattle and in domestic animals.

EFFECT: valuable properties of compounds.

6 cl, 3 tbl, 5 ex

FIELD: agents for plant protection useful in controlling of plant diseases of viral, bacterial and fungal etiology as well as in controlling of hookworms and arthropods.

SUBSTANCE: claimed agent contains (wt. %): water soluble product of iodine interaction with organic reagent 7-70; organic solvent 2-20; non-ionic surfactant 1-10; and water 1-90. Abovementioned organic reagent represents polyethylene glycol alkyl or alkylphenyl ester; and organic solvent represents ethylene glycol, triethylene glycol or polyethylene glycol. Weight ratio of iodine and organic reagent is from 1:2 to 1:10. As non-ionic surfactant preferably proxanol or oxyethylated alkylphenol based on polymer distillate is used.

EFFECT: simplified agent for plant protection.

3 cl, 3 tbl, 10 ex

FIELD: agents for plant protection useful in controlling of plant diseases of viral, bacterial and fungal etiology as well as in controlling of hookworms and arthropods.

SUBSTANCE: claimed agent contains (wt. %): water soluble product of iodine interaction with organic reagent 7-70; organic solvent 2-20; non-ionic surfactant 1-10; and water 1-90. Abovementioned organic reagent represents polyethylene glycol alkyl or alkylphenyl ester; and organic solvent represents ethylene glycol, triethylene glycol or polyethylene glycol. Weight ratio of iodine and organic reagent is from 1:2 to 1:10. As non-ionic surfactant preferably proxanol or oxyethylated alkylphenol based on polymer distillate is used.

EFFECT: simplified agent for plant protection.

3 cl, 3 tbl, 10 ex

FIELD: agents for plant protection useful in controlling of plant diseases of viral, bacterial and fungal etiology as well as in controlling of hookworms and arthropods.

SUBSTANCE: claimed agent contains (wt. %): water soluble product of iodine interaction with organic reagent 7-70; organic solvent 2-20; non-ionic surfactant 1-10; and water 1-90. Abovementioned organic reagent represents polyethylene glycol alkyl or alkylphenyl ester; and organic solvent represents ethylene glycol, triethylene glycol or polyethylene glycol. Weight ratio of iodine and organic reagent is from 1:2 to 1:10. As non-ionic surfactant preferably proxanol or oxyethylated alkylphenol based on polymer distillate is used.

EFFECT: simplified agent for plant protection.

3 cl, 3 tbl, 10 ex

FIELD: veterinary, in particular formulation for controlling of mammalian skin pests.

SUBSTANCE: claimed formulation contains (mass %): fipronil 0.3-5; methopren up to 1 %; benzylbenzoate 5-40 and balance: alcohol solvent. Formulation of present invention is useful in agriculture and treatment of domestic and wild animals, as well as treatment of apartments.

EFFECT: effective formulation for controlling of mammalian skin pests with prolonged storage time.

4 cl, 5 ex

FIELD: agriculture, veterinary.

SUBSTANCE: claimed formulation contains (mass %): deltametrin 0.01-0.05; acetone 5.0-10.0; dimethyl formamide 5.0-10.0; butanol 5.0-10.0; and balance: emulsifier.

EFFECT: preparation of increased activity.

2 cl, 1 tbl, 12 ex

Acaricide // 2280983

FIELD: agriculture.

SUBSTANCE: invention relates to acaricidal agent containing (mass %): alpha-cypermetrin 0.15-0.25; imiprotrin 0.10-0.35; N-octylbicycloheptadicarboximide 0.8-1.2; triethylene glycol 1.0-2.0; solvent 43.0-50.0; and balance: hydrocarbon propellant.

EFFECT: acaricide of increased effectiveness against red ticks (Rhipiceplalus everti).

2 cl, 4 tbl

FIELD: agriculture.

SUBSTANCE: smoke-flavoring preparation is used as growth promoter for green onion plant.

EFFECT: improved yield of green mass, increased safety for worker and environment.

3 tbl, 3 ex

FIELD: insecticides, agriculture.

SUBSTANCE: invention describes an acaricide composition comprising dihydrolinalool as an active component taken in the effective amount and special additives. The composition shows activity against mites in agricultural crop plantings.

EFFECT: valuable properties of composition.

1 tbl

FIELD: organic chemistry, agriculture.

SUBSTANCE: claimed composition contains (mass %): 2,4-dichlorophenoxyacetic acid 2-ethylehexyl ester 35-77; 2-methoxy-3,6,-dichlorobenzoic acid 2-ethylehexyl ester 5-11; surfactant 5-7.5; and balance: solvent.

EFFECT: herbicidal composition with increased storage stability and improved effectiveness in respect to wide range of weeds, including sow-thistle.

2 cl, 5 tbl, 16 ex

FIELD: agriculture.

SUBSTANCE: claimed composition contains arachidonic acid and urea in ratio of 1:1-1:8 and additionally lower C1-C4-alkohol as solvent. More particularly composition contains (mg/1 ml of solvent): arachidonic acid 0.01-1.00 and urea 0.01-3.00. Moreover composition optionally contains ionol as antioxidant in ratio arachidonic acid/ionol of 1:1.

EFFECT: composition for plant treatment with improved effectiveness.

3 cl, 9 tbl, 7 ex

FIELD: herbicides, agriculture.

SUBSTANCE: invention describes a herbicide composition comprising components in the following their contents, g/l: phenmedifam, 30-160; desmedifam, 30-160; mixture of non-ionogenic and anion-active surface-active substance, 150-350; liquid carboxylic acid amide, 20-200; co-solvent, 30-300; citric acid, 2-6; 1-phenyl-(1,2,4-triazole-4-yl)urea, 2-20; solvent, the balance, up to 1 l. The composition can comprise additionally ethofumezat in the amount 30 g/l. Invention provides the development of herbicide composition based on phenmedifam and desmedifam possessing the enhanced herbicide activity that allows reducing doses of preparations in their consumptions.

EFFECT: improved herbicide activity of composition.

2 cl, 2 tbl, 1 ex

FIELD: agriculture, fungicides.

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EFFECT: enhanced effectiveness of composition.

2 cl, 5 tbl, 2 ex

FIELD: agriculture, in particular potato storage technology.

SUBSTANCE: potato is treated with hydrogen peroxide solution to its spring inhibition. Said solution has pH of not more than 6 and contains silver, copper and zinc ions in amount of 10-20000 ppm. Solution additionally contains one acid selected from group containing peracetic acid, nitric acid, sulfuric acid and phosphoric acid. Solution is applied in form of dry fist, smoking agent or smoke. Solution comprises microdrops with diameter of 0.001-100 mum. Potato storage is carried out in high moisture conditions inhibiting thereby potato striking roots.

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19 cl

FIELD: plant protection.

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EFFECT: reduced stress effects on plants.

1 tbl

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