Plaster

FIELD: medicine.

SUBSTANCE: plaster can be used in cosmetology as local aid for making effect on skin and under-skin layers to achieve anti-cellulite improvement. Plaster has support layer made of polymer material covered with coating preventing penetration of flying compounds from polymer layer into surrounding surfaces when applying the plaster onto skin. Working matter is uniformly distributed onto surface of the layer. Plaster also has top protection layer. Working matter has orange essential oil, hips water-alcohol extract and menthol. Plaster can be used by patients suffering from gynecological diseases due to exclusion of warming effect. Lipid and water exchange can be activated in skin cells and skin turgor can be improved.

EFFECT: widened assortment of anti-cellulite plasters.

4 ex

 

The invention relates to outdoor applications, namely the patches used for exposure of the skin and smash of deep tissue, and can be used in cosmetology as a local tool to achieve anti-cellulite effect.

Cellulite is not just fat under the skin. This metabolism in subcutaneous adipose tissue, manifested in the accumulation of fat in the cells, the violation of the outflow of tissue fluid (edema), the deformation of cells (they get "spumescence"), as well as in the inflammatory response, developing as a consequence of these violations.

There are different approaches to treatment and prevention of cellulite, including compliance with certain diet; exercise; Spa treatments; the use of medicines containing drugs potassium and trace elements; drugs that strengthen the walls of blood vessels; drug-inhibitor of gastrointestinal lipases.

For local impacts apply peeling, anti-cellulite massage, mud wraps, seaweed, gel with anti-cellulite products.

The use of these funds is connected with the necessity of applying termeffects in conditions of special cosmetic treatments, which makes the process of temporary inconvenience and financial nature, and not everything is available, and unacceptable for women, the main category of consumers cellulite funds and programmes), which are contraindicated for heat treatments, massages, mud therapy due to the predisposition to gynecological diseases, for example, tumor focus.

Oral introduction into the body of drugs potassium to influence isotonicity cells, characterized by the response of the cardiac muscle by reducing its excitability and conductivity, depressed automaticity and contractility of the myocardium. The great danger of this kind of side effects (Mashkovsky PPM, Medicines. In two parts., part II - M.: Medicine, 1993, p.143).

The prior art balm-gel "Russian bath" from cellulite by RF patent No. 2203023 (publ. 2003.04.27., Bulletin No. 12, 49) for local effects on problem areas of the skin. The composition is used in combination with the indispensable wrap, and with a warming effect to drain excess fluid, leaves traces on clothing, i.e. has a low consumer properties and contraindications for specific groups of women, which narrows the number of potential users. Multicomponent composition complicates the technological process in the manufacture.

Known biologically active substance according to the patent of Russian Federation №2224534, publ. 2004.02.27, Bulletin No. 6, s, the use of which requires more than simply applied to the skin, and is accompanied by massage, which limits its range of application among groups of consumers. In addition, a large number of essential oils in the composition may cause allergic reactions.

Thus, each of the known from the prior art anti-cellulite means has an unpleasant restrictions that need to be overcome.

More simple and convenient form for local application on the skin of the existing tools is the patch, appliciruemah in the problem area and with precise positioning.

Patches of cellulite orientation in the prior art is not found.

The closest in composition of substances and elements included in its structure, is the patch RF patent No. 2180857 (publ. 2002.03.07., Bulletin No. 9, pp.163)containing a supporting layer made of polymer material with a coating that prevents the spread in the environment when apliciranje on the skin of volatile compounds from the polymer layer, which is uniformly distributed operating means, and a protective layer.

The patch in the prototype relates to irritant, anti-inflammatory action, activates the blood flow. The composition of the patch is not optimized to the specific conditions associated with cellulite. Fir needle oil is, used as an active tool, helps to create a relaxing effect, and in the fight against cellulite important is the turgor of the skin. In addition, the disadvantages of the prototype include a heating effect, which is undesirable for women with gynecological pathologies.

The present invention is to expand the range of local patches of skin exposure to specific anti-cellulite orientation in accordance with existing demand while ensuring the possibility of using a group of consumers with gynecological pathologies due to the exclusion of a warming effect in the simultaneous activation of lipid and water metabolism in the cells knives and increase its turgor.

The problem is solved proposed patch, which includes a support layer made of polymer material with a coating that prevents the spread in the environment when apliciranje on the skin of volatile compounds from the polymer layer, which is uniformly distributed operating means, and a protective layer. The peculiarity lies in the fact that the current means includes orange essential oil, water-alcohol extract of wild rose and menthol.

A comparison of the proposed patch with the prototype shows that the proposed patch is different is tsya other applicable means, comprising an effective amount of essential oil of orange, preferably from 2.2 to 3.0 wt.%, water-alcohol extract of rosehip, preferably from 53,0 to 61.0 wt.%, and menthol, preferably from 2.0 to 2.8 wt.%, sufficient to provide anti-cellulite effect.

The analysis of the prior art showed that the unknown patch, which would place the proposed combination of signs. But it is precisely stated set of features helps to achieve the above technical result and to solve the problem.

Orange essential oil contains vitamins C, B1In2, A and P, a large number of sugars and minerals (calcium, phosphorus, potassium), citric acid, volatile. Vitamin C is involved in the synthesis of collagen, the b vitamins are involved in the process of fat metabolism.

Water-alcohol extract of rose hips contain vitamins C, K, R, A, B1In2B6E , flavonoids, sugars, organic acids, potassium, sodium, calcium, phosphorus, iron, magnesium, catechins.

Ascorbic acid, determining the biological activity of these two components of the patch significantly increases the redox processes in the skin, is involved in the synthesis of collagen, stabilizes the level of adrenaline and other catecholamines that controls the alpha - and beta-receptors of the skin, which is prevlayout functions of fat cells, play a major role in the development of cellulite. Under the influence of adrenaline is increased tissue metabolism, improves the flow of fluid from the swollen cells.

Potassium present in the essential oil of orange and in aqueous-alcoholic extract of rose hips, ions which support isotonicity cells, when introduced through the skin delicately (unlike pills injection of potassium in the treatment of cellulite) affects the body, stimulating the release of adrenaline.

This orange essential oil is a function of the fat component adhesive that softens the skin and has a delicate flavor (unlike the specific and the sharp smell of pine oil prototype). Orange oil is not only highly compatible with the skin, but also resistant to rancidification by sharing with a water-alcohol extract of rose hips, which gives the patch stability even after prolonged storage.

Water-alcohol extract of rose hips as a source of important anti-cellulite substances, it has the ability to remove the products of the decay of tissues, stimulates the excretory function of the skin, especially with repeated use of the patch.

Menthol relates to stimulating the receptors of the skin and subcutaneous tissues. Very easily soluble in alcohol, easily in fatty acids. When rubbing into the skin m is ntol irritates nerve endings, exhibits a cooling effect that when using it in the patch prevents diaper rash, which may occur in the area of the contacting surfaces of the patch and the skin. Stimulates the receptors of the skin and subcutaneous formations, has an impact on regulatory processes, normalizes fat metabolism in Addition, menthol, having absorbability and solubility in the essential oil of orange and in the spirit of the hips, draws these components and together with them diffuses into the skin and into the subcutaneous tissue. While the menthol helps to improve the consistency of the adhesive mass deposited on a support layer, its softness.

Substances ingredient of plaster evenly distributed in bioadhesive polymer layer consisting of spirtosoderjasimi polymers that are valid for use in medicine (one of which is a binder, and a second wetting agent, their combination allows to create a uniform stagnant mass), give the patch a full completeness for the correction of cellulite processes and texture, appropriate cosmetic purpose. The patch is non-toxic, which is confirmed by the Protocol Toxicological evaluation Center for state sanitary and epidemiological surveillance in Moscow, provides for minimizing leakage and evaporation components acting is on the money.

Examples of specific performance.

Example 1. to 5.2 g (2.6 wt.%) essential orange oil mixed with 4.8 g (2.4 wt.%) menthol, then add 114 g (57 wt.%) alcoholic extract of rose hips, the resulting mixture is combined with 76 g (38 wt.%) pharmaceutically acceptable spirtosoderjasimi polymers (polyvinylpyrrolidone mol. mass 850000-1200000 and polyethylene glycol (mol. weight of 400 in the ratio of 1.7:1). The mixture is stirred for from 1.0 to 1.15 PM the mixing Process finish when you achieve homogeneity of the solution (visual inspection). The resulting mixture was poured into an accumulation tank for sludge from bubbles. Time advocate for 1.5-2.0 hours. The resulting mass is put on a metallized polyethylene terephthalate film (on THE 6-19-611 or THE 6-19-371) - support layer of adhesive; can be used any polymer material acceptable for use in medicine. Film with a deposited layer of a specified mass passes through the drying chamber. Then the polymer layer, in which evenly distributed the current tool, contains 88,67% of a mixture of polymers, 4,58% pure essential orange oil, 2,43% rosehip extract and is a solid surface of the transparent mass.

At the outlet from the chamber film coated with a polymer layer mass close with a protective layer of paper, adhesive, dividing to sticky the medical films or polyethylene terephthalate film with a silicone coating.

Received the patch, passing through a system of longitudinal and transverse knives, cut in the required dimensions for length and width. Made the patch is placed on the packaging machine and method of heat sealing packaged in individual packages.

Example 2. to 5.2 g (2.6 wt.%) essential orange oil mixed with 4.8 g (2.4 wt.%) menthol, then add 114 g (57 wt.%) alcoholic extract of rose hips, the resulting mixture is combined with 76 g (38 wt.%) pharmaceutically acceptable spirtosoderjasimi polymers (polyvinyl butyral acetal butyric aldehyde and polyvinyl alcohol with a degree of polymerization of 500-800 and polyethylene glycol (mol. weight of 400 in the ratio of 1.7:1). The mixture is stirred for from 1.0 to 1.15 p.m. And hereinafter in example 1.

Example 3. to 5.2 g (2.6 wt.%) essential orange oil mixed with 4.8 g (2.4 wt.%) menthol, then add 114 g (57 wt.%) alcoholic extract of rose hips, the resulting mixture is combined with 76 g (38 wt.%) pharmaceutically acceptable spirtosoderjasimi polymers (polyvinylpyrrolidone mol. mass 850000-1200000 and polyethylene glycol (mol. weight of 400 in the ratio of 1.7:1). The mixture is stirred for from 1.0 to 1.15 PM the mixing Process finish when you achieve homogeneity of the solution (visual inspection). Received mesh drain the holding tank for sludge from bubbles. Time advocate for 1.5-2.0 hours. The resulting mass is put on a siliconized film (on THE OP 13-0281020-15) - support layer of adhesive; can be used any polymer material acceptable for use in medicine. And further in the text of example 1.

Example 4. to 5.2 g (2.6 wt.%) essential orange oil mixed with 4.8 g (2.4 wt.%) menthol, then add 114 g (57 wt.%) alcoholic extract of rose hips, the resulting mixture is combined with 76 g (38 wt.%) pharmaceutically acceptable spirtosoderjasimi polymers (polyvinyl butyral (acetal butyric aldehyde and polyvinyl alcohol with a degree of polymerization of 500-800 and polyethylene glycol (mol. weight of 400 in the ratio of 1.7:1). The mixture is stirred for from 1.0 to 1.15 PM the mixing Process finish when you achieve homogeneity of the solution (visual inspection). The resulting mixture was poured into an accumulation tank for sludge from bubbles. Time advocate for 1.5-2.0 hours. The resulting mass is put on a siliconized film (on THE OP 13-0281020-15) - support layer of adhesive; can be used any polymer material acceptable for use in medicine. And further in the text of example 1.

The patch containing the reference layer made of a polymeric material with a coating that prevents the spread in the environment when apliciranje on the skin of volatile compounds from karnego layer, which evenly distributed the current tool, and a protective layer, characterized in that said operating means includes orange essential oil, water-alcohol extract of wild rose and menthol, taken in an effective amount.



 

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