Agent for treatment of urolithiasis


FIELD: medicine, pharmacy, phytotherapy.

SUBSTANCE: invention relates to an agent that can be used in treatment of urolithiasis. Agent represents the herbal species comprising the following components: common juniper fruits, common hop cones, cowberry leaves, horse-tail herb, medicinal sweet clove herb, shepherd's purse herb, cornflower flowers, flax seeds, parsley herb, madder roots, linden flowers, knot-grass herb, fenestrate Saint-Johns-wort herb, field rest-harrow roots, Java tea herb, medicinal garden angelica rhizomes and roots, medicinal anise fruits, birch buds, tricolor violet herb, fennel fruits, maize stigmas, sandy common immortelle flowers, sweet flag roots and rhizomes, licorice roots, medicinal dandelion roots, common berry herb and common wormwood herb taken in the definite ratio. Intake of the proposed agent results to elimination of concretions from kidneys, disappearance of inflammatory symptoms, normalization of functional state of kidneys and the stable remission in the patient state and the absence of adverse reactions and toxic effect. Invention can be used in treatment of urolithiasis.

EFFECT: improved and enhanced properties and effectiveness of agent.

2 tbl, 4 ex

 

The invention relates to the field of pharmacy, in particular herbal medicine and can be used for the treatment of urolithiasis.

Urolithiasis continues to be one of the first places among all urological diseases, averaging across Russia 34,25% (Zernov NICHOLAS, Yanenko E.K. Surgical treatment of Staghorn calculi protease. Urology, 2004, No. 1, p.34-38).

There is a method of treating kidney stones nephrolithiasis under the scheme, including the use of drugs: blamore under the control of the pH of urine, aleirina, chimes, festal in normal doses and diuretic herbs used 10 days in a month (jurak B.C., Savchuk, V.I. Zastosowania citrate sums "Blamore" in complex licuan cecosesola stone. In the book: Urolithiasis. Edited by Prof. Pereverzev. Kharkov, 1999, s-399).

But when using this method of treatment does not always achieve the desired clinical effect and some patients sometimes allergic skin rash, dyspepsia, and nausea (jurak B.C., Savchuk, V.I. Zastosowania citrate sums "Blamore" in complex licuan cecosesola stone. In the book: Urolithiasis. Edited by Prof. Pereverzev. Kharkov, 1999, s-399).

For many years, was created recipes for medicinal charges for treatment of kidney stones, such as collection, consisting of pods FAS is whether ordinary 20,0, leaves of motherwort hairy 25,0, roots of Berenice (saxifrage) 10,0, grass gryzhnika smooth 10,0, grass shepherd's purse is 5.0. A mixture of (2-style. spoons) zaparivajut in a glass boiling water, insist 3-4 hours, drink 2 table. spoon 3-4 times a day (Kruglyak L. kidney Stones. St. Petersburg, Peter, 2002, s).

However, the fee is not always effective due to inadequate diuretic actions and, as the leaves of motherwort have hairy commulative properties with long-term use of this collection of possible toxic effect.

It is also known the use of the collection, which consists of the fruits of anise 50,0, fruits parsley seed 50,0, grass shepherd's purse 15,0, the fruits of Juniperus communis l 15,0, the root of harrow barbed 15,0, the root of lovage drug 15,0, the root of the dandelion 15,0. It is recommended to take the decoction obtained from two tablespoons of the mixture and boiled in two glasses of water to drink in two steps (Kruglyak L. kidney Stones. St. Petersburg, Peter, 2002, p.95).

However, this collection may cause side effects in the form of strengthening choleresis, further leading to attacks of cholecystitis due to the relatively high content of fruits of anise ordinary. In some patients, this collection can cause movement of calculus, which leads to pain syndrome and sometimes urgent hierarchicalcodelist.

Famous collection, including nettle 5,0, calamus rhizomes of marsh 5,0, peppermint leaves 5,0, grass horsetail 15,0, black elderberry flowers 15,0, lime flowers, heart 15,0, the fruits of Juniperus communis l 15,0, hips 15,0. Broth, cooked at the rate of 1:20, take 1 Cup in the morning and evening (Tiktinsky O.A., Alexandrov VP Urolithiasis. St. Petersburg, Peter, 2000, s).

Use this collection does not always lead to clinical effect, as it does not have a significant effect on diuresis and not always normalizes the function of the urinary system.

The prototype of the present invention is the collection consisting of 14 species of medicinal plants: herbs of lavender, spike 10,0, black currant leaves 10,0, birch leaves 10,0, budry plyuschevidnaya 10,0, juniper berries ordinary 10,0, hop cones 10,0, cowberry leaf 20,0, plantain leaves 28,0, fruits strawberry 60,0, horsetail shoots 60,0, grass clover medicinal 50,0, grass shepherd's purse 15,0, flowers of cornflower blue 30,0, seed flax ordinary 40,0.

Available components brew 10 g in 750 ml of boiling water, boil for 5-6 minutes, insist 2 hours. The discharge of the stone, the dose of the mixture is recommended (Kruglyak L. kidney Stones. St. Petersburg, Peter, 2002, s) be reduced to 5 g per 500 ml of boiling water (Tiktinsky A, Alexandrov VP Urolithiasis. Saint-Petersburg. Peter, 2000, p.223).

The collection of the prototype does not always produce the desired clinical effect. When using this collection of possible allergic reactions to the herbs of the lavender, spike cough and runny nose. Due to the high content of plantain leaves patients with high acidity may experience dyspepsia in the form of heaviness in the epigastric region, nausea and constipation. With long-term use of the fruit of the strawberry some patients may develop hypersensitivity to him, accompanied allergic rash. Boudreau plyuschevidnaya can sometimes cause irritation of the kidneys, reflected in rapid urination and discomfort in the lumbar region and back. As medicinal raw materials included in the collection, not homogenized, it does not fully extraction of active substances, and thereby the clinical effect is weakened.

The invention aims to strengthen the clinical steps of collecting and receiving therapeutic effect in terms of the dissolution and removal of stones and sand from the kidneys of the patient in the absence of adverse reactions and toxic effects.

The problem is solved in that the tool representing the herbal collection includes fruits morewell the ka ordinary, hop cones ordinary leaves of bilberry, horsetail grass, grass clover medicinal, herb shepherd's purse, cornflower blue, flax seeds, additionally includes 19 medicinal plants: grass, parsley roots of madder, lime flowers, grass knotweed, the herb St. John's wort herb, the roots of harrow field, grass renal tea, rhizomes and roots of dagala medicinal, fruits anise drug, birch buds, grass tricolor violet, fennel fruit, corn stigmas, immortelle flowers sand, roots and Acorus calamus rhizome, licorice root, the roots of dandelion, grass, bearberry leaf the herb wormwood at the following mass ratio of components:

Juniper fruits3-5
Hop cones9-11
Cranberries, leaves7-9
Horsetail grass6-8
Clover medicinal, herb8-10
Shepherd's purse, grass7-9
Cornflower blue flowers4-6
The flax seed10-12
Parsley, grass9-11
Madder roots5-7
Linden flowers14-16
Knotweed, grass7-9
Hypericum perforatum, grass8-10
Of harrow field, roots7-9
Kidney tea, herb10-12
Dagele drug, rhizomes and roots7-9
Anise medicinal, fruit11-13
Birch buds5-7
Tricolor violet, grass12-14
Fennel fruit7-9
Cornsilk6-8
Immortelle sandy, flowers4-6
The roots and rhizomes of calamus3-6
Licorice root6-8
Dandelion roots5-7
The bearberry leaf, grass3-5
Wormwood, grass2-4

The fruits of juniper common anti-inflammatory and bactericidal effects. They provide filtered in the glomeruli and inhibit reverse resorption of ions of sodium and chlorine in the convoluted tubules of the kidneys, thereby, improve their function, increase diuresis and contribute to the discharge of small spiral the clients and sand on the ureter.

Hop cones ordinary provide anti-inflammatory, antiulcer, hyposensitizing and analgesic effect. They regulate kidney function, increased urination, promote the passage of sand through the ureters and the removal of his bladder. Hop cones reduce spasms in the intestines, promote the secretion of bile from the gallbladder and generally regulate mineral metabolism.

The cowberry leaves have antibacterial, antiseptic, anti-inflammatory, astringent, diuretic and choleretic action. They reduce the permeability and fragility of capillaries, improve blood supply to the gastric mucosa, thereby promote epithelialization of ulcers of the stomach and duodenum.

The herb horsetail causes hemostatic and anti-inflammatory effect. She also has a strong diuretic effect, plays an important role in metabolism and functional activity of connective tissue, mucous membranes and blood vessel walls. In urine silicon substances contained in the herb horsetail, form protective colloids, preventing crystallization of some mineral components and thus hinder the formation of urinary stones and contribute to their dissolution.

Grass clover drug has pronounced detoxication the s ' property, increases the phagocytic activity of leukocytes, improves peripheral blood flow to the tissues of the liver, exhibits antibacterial properties, improves liver function, strengthens haeres.

Grass shepherd's purse has a volatile and expressed a haemostatic effect. High efficiency shepherd's purse in renal bleeding, so it plays an important role in stopping bleeding that occurs after the passage of concretions and fine sand on the ureter, leading in some cases to injuries.

Cornflower blue have anti-inflammatory and disinfectant properties. They are effective for urolithiasis as reinforce filtering and improve microcirculation in the renal glomeruli and tubules. They also contribute to the discharge of urine and have an antimicrobial effect in the kidney, ureter and bladder.

Flax seeds have anti-inflammatory, coating and minor analgesic properties. When intake per os flax seeds are covered with a thin layer of mucous membrane of the stomach and duodenum, protecting it from irritation. This action is especially effective for stomach ulcers, accompanied by hypersecretion. Under the influence of the enveloping means decreases the absorption of the of Chechnya infectious toxins, which can cause the phenomenon of intoxication of the organism.

The parsley herb has antimicrobial property, improves choleras and enhances filtration in the renal tubules, thereby helps dissolve stones. It also stimulates diuresis and normalizes the function of the bladder, promotes the removal of small stones and sand from the ureter.

The roots of the madder contribute to the loosening of kidney stones, trigger a process of grinding and removal of stones and sand from the kidneys and urinary tract. In addition, Morena dye increases energy and enhances the peristaltic contractions of the musculature of the renal pelvis and ureter, at the same time, reduces spasms, facilitating the passage of kidney stones and urinary tract.

Linden flowers have antimicrobial, anti-inflammatory and anti-edema effect, have a calming effect. In addition, lime flowers help to increase choleresis and facilitate the flow of bile into the duodenum, stimulates the secretion of gastric juice, increase diuresis, increase ecsoc-rinnooy the function of the pancreas.

Grass knotweed different diverse clinical properties, including antimicrobial, anti-inflammatory and astringent. It also increases diuresis, displays with mocha the excess of sodium ions and chlorine, resulting in increased filtering of renal glomeruli and reduced reverse resorption in the renal tubules. In the grass knotweed contains soluble compounds of silicic acid, which in significant concentrations are removed with the urine, thereby helping to dissolve kidney stones and preventing formation of new ones.

The herb St. John's wort herb has antimicrobial, antibacterial, anti-inflammatory and astringent effect, improves bile secretion into the duodenum, restores normal peristalsis, increases digestive capacity of the gastrointestinal tract, relieves spasms of the blood vessels, especially capillaries, providing capillaries strengthening effect, improves venous circulation and overall blood supply to the stomach. Herb Hypericum perforatum enhances regenerative properties of tissues, thereby promotes scarring ulcers of the stomach and duodenum.

The roots of harrow field cause diuretic and laxative action and are anti-inflammatory and laxative effect. In addition, the roots of harrow field reduces the permeability and fragility of capillaries, causing a diuretic effect, promote dissolution of the stones and the subsequent removal of small stones and sand from the kidneys. They reduce painful the ity with the passage of sand through the ureters and bladder.

Grass kidney tea has a pronounced diuretic, promotes the excretion of chloride, urea and uric acid, which causes dissolution of stones, especially urates. The combination of mild diuretic effect and some antispasmodic actions helps to reduce pain during bouts of kidney stones. Kidney tea has a beneficial effect on patients with gallstone and kidney stone disease, it improves appetite, reduces mucus and blood in the bile, and normalizes the function of the kidneys and bladder.

Rhizomes and roots of dagala drugs have anti-inflammatory, antispasmodic and diaphoretic action. They also have antibacterial and diuretic effect and increase the filtration in the kidneys and contribute to the passage of sand along the ureter.

Anise fruits medicinal anti-inflammatory, antispasmodic and a bactericidal effect. They reduce spasms of smooth muscles of the intestines and urinary tract, have a diuretic and anti-inflammatory effect, helps to normalize the function of the kidneys and bladder and improve the removal of small stones and sand from the kidneys and passing them through the ureter.

Birch buds have antiseptic, anti-inflammatory, deinfitely them and diuretic action. They also contribute to the dissolution of rocks, mainly of phosphate and carbonate of origin. In addition, birch kidneys increase diuresis and have a positive effect in the removal of small stones and sand through the ureters and removing them from the bladder.

Grass tricolor violet causes anti-inflammatory, spasmolytic, choleretic and diuretic effect, but also reduces the permeability of blood vessels and inhibits the development of traumatic edema, thus enhancing diuresis helps remove sand from the kidneys and urinary tract.

Fennel fruit increase the secretion of digestive glands, have choleretic, spasmolytic and diuretic effect, have some antibacterial effect, increase the secretion of pancreatic juice and bile excretion.

Corn silk can cause marked choleretic effect, regulating the secretion of bile from the gall bladder and the outflow of pancreatic juice, thereby normalize the evacuation of food from the stomach. They help stop nausea and vomiting, as well as accelerate the clotting of blood and cause hemostatic effect in gastric ulcer and duodenal ulcer.

Immortelle flowers sand have anti-inflammatory, antibacterial, inflammatory and choleretic on the op perate. They stimulate the secretion of gastric juice and activate the secretory capacity of the pancreas, has antispasmodic effects on the blood vessels, helping to improve circulation of the stomach and duodenum.

The roots and rhizomes of calamus are able to exert anti-inflammatory, bacteriostatic, fungistatic and some antispasmodic action. They are also weak analgesic effect and contribute to the cure of chronic gastritis, especially in cases with low acidity of gastric juice, as well as accelerate the scarring ulcers of the stomach and duodenum.

Licorice root has a pronounced anti-inflammatory properties and also stimulates the adrenal cortex, providing corticosteroidogenic effect, improves choleris, reduces the viscosity of the bile, thereby restoring impaired liver function.

Dandelion roots medicinal normalize secretory and motor function of the stomach and intestines, increasing bile secretion and the secretion of digestive glands. They have antispasmodic, diuretic and laxative effect, stimulates appetite, improves digestion and normalizes the evacuation of food from the stomach.

Bearberry common causes diuretic and antibacterial action, in addition, it has spasmo eticheskim and choleretic action, positively affects the vessels of the terminal vascular beds and stimulates regeneration of liver cells. Due to its disinfectant properties, it reduces inflammation in the biliary tract and partially gall bladder.

Absinth sage herb has anti-inflammatory, bactericidal and fungicidal properties and also contributes to the stabilization of immune responses, enhances the proliferative phase phenomena in places of ulcers of the stomach or duodenum, thereby providing an anti-ulcer action. She removes diarrhoeal phenomenon, improves digestion and has anti-parasitic and anthelminthic action.

The mixture is ground to a powder consistency, then 2/3 teaspoon brewed in 300 ml of boiling water, insist 15 minutes, Take 100 ml three times a day after meals at normal and high pH, while cold before eating for one and a half months.

As examples are extracts from the histories.

Example 1.

And/b No. 1021. Patient I., 44.

Diagnosis: kidney stones

Complains of pain in the lumbar region with irradiation in the right thigh, dysuric phenomena in the form of painful urination, urine color "meat slops", reducing the amount of urine. Considers himself ill about 5 years when he first came to Noah is their pain in the lumbar region, dysuric phenomena. Medical help is not sought. About a week ago after exercise increased pain in the lumbar region, decreased amount of urine appeared dysuric phenomena. Hospitalized in therapeutic monitoring.

Objectively: the State of moderate severity. The skin is clean. Pastos person. Pulse 88 beats per minute, rhythmic. HELL 130/90. Muffled heart sounds. The vesicular breathing. Tongue coated white bloom. The abdomen is soft. Liver, spleen not palpable. Is palpated painful right kidney. Positive symptom tapping on the lumbar region on the right. Peripheral edema no.

The wedge. blood analysis: Hb 120 g/l; Er,8×1012/l, leukocytes 8.6×109/l; B.1, e, p.3, S. 66, HP 22, m 6; ESR 25 mm/hour.

Urinalysis - urine with a reddish shade, cloudy, sour 200,0, beats. V, protein 0,66%, no sugar; er. 20-25 in PSR.; leukocytes in 10-15 PSR.; bacteria 150,000 in 1 ml; the cylinders are missing.

Examination of urine on Nechiporenko: leukocytes 6000 in 1 IO; erythrocytes 9000 in 1 ml; cylinders 2.

Biochemical blood test: whole protein 80 g/l; albumin 60%: globulins α13%; α28%; β12%; γ17%; creatinine 115 µmol/l; urea 8.3 µmol/l; uric acid 430 µmol/l; glomerular filtration 80 ml/min; the tubular reabsorbtion 96%.

Ultrasound of the kidneys and urinary tract kidney: the floor of the local system of normal size and shape, not deformed. In the pelvis of the right kidney are rendered 3 concrement in the form of a hyperechogenic rounded education with a diameter of 5 mm, the ureters and the bladder is not changed.

Review radiograph 3 projections of the right kidney are defined shadows suspicious concretions.

In/in urography - buds usually are not changed in size and shape. Abdominal system of the kidneys is not changed, in the pelvis of the right kidney are rendered 3 concrement in the form hogenova rounded education with an acoustic shadow in diameter 5 mm

In the clinic the patient were treated: avison 2 so 3 times a day, nitroxoline 0.05 g 4 times a day, 2% solution nospy - 2,0.

On the background of therapy decreased pain in the lumbar region, at the same time increased dysuric phenomena, urine remains tinged with red. Urinalysis - urine with a reddish shade, cloudy, sour 200,0 beats. V protein of 0.066% no sugar; er. 30-35 in PSR.; L10-12 in PSR.; bacteria 45000 1 ml urine on Nechiporenko: 5000 leukocytes in 1 ml; erythrocytes 7000 in 1 ml; the cylinders are missing.

The wedge. blood analysis: Hb 115 g/l; er. 3,7 1012/l, WBC 8.4 109/l; B.1, e, p.4, c.66, l, m; erythrocyte sedimentation rate of 30 mm/hour.

Biochemical blood test: whole protein 78 g/l; albumin 52%; globulins α14%; α29%; β12%; γ17%; creatinine 110 µmol/l; urea 8.2 mmol/l; uric acid 430 is KMOL/l; glomerular filtration 84 ml/min; the tubular reabsorbtion 98%.

Ultrasound of the kidneys and urinary tract kidney: pelvis of the right kidney are rendered 3 concrement in the form of a hyperechogenic rounded education diameter 5 mm

Due to the lack of a positive result of the treatment to therapy the patient is assigned herbal collection, including: the fruits of Juniperus communis l 3,0 (15 g), hops ordinary 9 (45 g), leaves of cowberry 7 (3 5 g), the herb horsetail 6 (30 g), grass clover medicinal 8 (40 g), grass shepherd's purse 7 (35 g), cornflower blue 4 (20 g), flax seeds 10 (50 g), parsley herb 9 (45 g), the roots of the madder 5 (25 g), lime flowers, 14 (70 g), grass knotweed 7 (35 g), herb Hypericum perforatum 8 (40 g), roots of harrow field 7 (35 g), grass kidney tea 10 (50 g), rhizomes and roots of dagala drug 7 (3 5 g), anise fruit medicinal 11 (55 g), birch buds 5 (25 g), grass tricolor violet 12 (60 g), fennel fruit 7 (35 g), corn silk 6 (30 g), immortelle flowers sand 4 (20 g), roots and rhizomes of calamus 3 (15 g), licorice root 6 (30 g), the roots of dandelion 5 (25 g), grass, bearberry leaf 3 (15 g), herb wormwood 2 (10 g).

The mixture was ground to a powder consistency, then 2/3 teaspoon was poured on 300 ml of boiling water, insist 15 minutes the mixture stood for, and ill the th received 100 ml three times a day for two months.

After this treatment the patient's condition has improved. No pain in the lumbar region, dysuric phenomena, normal color of urine.

Objectively: the patient is in satisfactory Condition. The skin is clean. The heart rate of 78 beats per minute, rhythmic. HELL 130/80. Muffled heart sounds. The vesicular breathing. The language clean. The abdomen is soft. Liver, spleen not palpable. The kidneys are not palpable. Symptom tapping on the lumbar region is negative on both sides. No edema.

The wedge. blood analysis: Hb 125 g/l; er. 4×1012/l, leukocytes 6,5×109/l; B.1, item 4, S. 65, L.25, m 5; ESR 10 mm/hour.

Urinalysis: color - yellow straw, transparent, beats. century 1015, no protein, no sugar; er. 0-1 in PSR.; leukocytes in 1-2 PSR.; bacteria are not defined.

Examination of urine on Nechiporenko: leukocytes 3000 1 NC; erythrocytes 500 in 1 ml; the cylinders are missing.

Biochemical blood test: whole protein 78 g/l; albumin 60%: globulins α12%; α28%; β13%; γ17%;; creatinine 70 µmol/l; urea 4.5 mmol/l, uric acid 320 µmol/l; glomerular filtration 90 ml/min; the tubular reabsorbtion 98%.

Ultrasound of the kidneys and urinary tract: kidneys of normal size and shape, cavity system is not deformed. The concretions are not rendered. The ureters and bladder are not changed.

In/in urography - kidney normal shape and size, strips the Fes system of the kidneys is not changed. The concretions are not defined. Excretory function is not impaired.

Remission after therapy is 12 months.

Example 2

And/b No. 325. Patient P., 37 years.

Diagnosis: kidney stones, stones in the left kidney.

Complains stabbing pain on the left with irradiation in the groin area, painful urination, dark urine, fever up to 38°C. Ill for about 3 years, when first appeared dysuric phenomena, puffy face in the morning. Ultrasound kidney first discovered calculus of the left kidney. Not treated. Yesterday, after a workout in the gym there was a severe pain in the lumbar region to the left, pain during urination, dark urine, increased temperature to 37.8°C. Applied for medical assistance in Policlinico, where a doctor was sent for therapeutic monitoring.

Objectively: the State of moderate severity. The skin is clean. Pastos person. Pulse 86 beats per minute, rhythmic. HELL 135/90. Muffled heart sounds. The vesicular breathing. The language clean. The abdomen is soft. Liver, spleen not palpable. Is palpated painful left kidney. Positive symptom tapping on the lumbar region on the left. Peripheral edema no.

The wedge. blood analysis: Hb 118 g/l; er. 3,7×1012/l, leukocytes 8,4×109/l; a, p.5, S. 64, HP 21, 7 m; erythrocyte sedimentation rate of 20 mm/hour.

The clinically. urine analysis - Qty - 200,0, m the percentage, sour 200,0 beats. century 1011, protein 0,33%, no sugar; er. 30-35 in PSR.; leukocytes in 15-20 PSR.; bacteria 100000 in 1 ml.

Examination of urine on Nechiporenko: leukocytes 5700 in 1 ml; erythrocytes 8000 in 1 ml.

Biochemical blood test: whole protein, 75 g/l; albumin 50%: globulins α14%; α28%; β15%; γ23%; creatinine 118 µmol/l; urea of 8.2 mmol/l, uric acid 430 µmol/l; glomerular filtration 78 ml/min; the tubular reabsorbtion 96%, uric acid 430 µmol/L.

Ultrasound of the kidneys and urinary tract: kidney is normal in size and shape, cavity system is not deformed. In the pelvis of the left kidney defined 2 concrement in the form of a hyperechogenic rounded education with a diameter of 6 mm, the ureters and the bladder is not changed.

Review the chest x-ray in the projection of the right kidney are defined shadows suspicious concretions.

In/in urography - buds usually are not changed in size and shape. Abdominal system of the kidneys is not changed, in the pelvis of the right kidney visualized 2 concrement in the form hogenova rounded education with an acoustic shadow in diameter 6 mm Excretory function is not impaired.

In the hospital the patient were treated: avian 2 so 3 times a day, nitroxoline 0.05 g 4 times a day, the solution shpy 2-2,0,

On the background of therapy pain in the renal region has not diminished, is still painful urination, the body temperature of 37.5°C.

The wedge. blood analysis: Hb 120 g/l; er. 3,8 10×12/l, leukocytes 8,2×109/l; a, paragraph 5, p.63 L.22, m 8; erythrocyte sedimentation rate of 22 mm/hour.

The clinically. urine analysis - Qty - 250,0, cloudy, sour 200,0, beats. century 1012, protein 0,33%, no sugar; er. 25-20 in PSR.; leukocytes 35-50 in PSR.; bacteria more than 100,000 in 1 ml.

Examination of urine on Nechiporenko: leukocytes 4700 in 1 ml; erythrocytes 6000 in 1 ml.

Biochemical blood test: whole protein 72 g/l; albumin 48%: globulins α14%; α29%; β16%; γ23%; creatinine 116 µmol/l; urea 8.0 µmol/l; uric acid 410 µmol/l; glomerular filtration 76 ml/min; the tubular reabsorbtion 97%, uric acid 430 µmol/L.

Ultrasound of the kidneys and urinary tract in the pelvis of the left kidney visualized 2 concrement in the form of a hyperechogenic rounded education diameter 6 mm

Due to the lack of a positive result of the treatment to therapy the patient is assigned herbal collection, including: the fruits of Juniperus communis l 4,0 (20 g), hops ordinary 10 (50 g), leaves of cowberry 8 (40 g), horsetail grass 7 (35 g), grass clover medicinal 9 (45 g), grass shepherd's purse 8 (40 g), cornflower blue 5 (25 g), flax seeds 11 (55 g), parsley herb 10 (50 g), the roots of the madder 6 (30 g), lime flowers, 15 (75 g), grass knotweed 8 (40 g), herb Hypericum perforatum 9 (45 g), roots of harrow polevogo (40 g), grass kidney tea 11 (55 g), rhizomes and roots of dagala drug 8 (40 g), anise fruit medicinal 12 (60 g), birch buds 6 (30 g), grass tricolor violet 13 (65 g), fennel fruit 8 (40 g), corn silk 7 (35 g), immortelle flowers sand 5 (25 g), roots and rhizomes of calamus 4 (20 g), licorice root 7 (35 g), the roots of dandelion 6 (30 g), grass bearberry ordinary 4 (20 g), herb wormwood 3 (15 g).

The mixture was ground to a powder consistency, then 2/3 teaspoon was poured on 300 ml of boiling water, insist 15 minutes the mixture was defended and the patient was taken in a 100 ml three times a day for two months.

After this treatment the patient's condition has improved. No pain in the lumbar region, dysuric phenomena, normal color of urine.

Objectively: the patient's Condition is satisfactory. The skin is clean. The heart rate of 74 beats per minute, rhythmic. HELL 115/80. Muffled heart sounds. The vesicular breathing, wheezing no. The language clean. The abdomen is soft. Liver, spleen not palpable. The kidneys are not palpable. Symptom tapping on the lumbar region is negative on both sides. No edema.

The wedge. blood analysis: Hb 122 g/l; er. 4,1×1012/l, leukocytes 6,0×109/l; e, p. 2, c.67 L. 24, m; erythrocyte sedimentation rate of 7 mm/h.

The wedge. urine analysis - Qty 210,0; straw-yellow, slightly transparent, beats. century 1015, be the ka no, no sugar; erythrocytes 0-1 in PSR.; the leukocyte - 0-1V PSR.; bacteria are absent, the cylinders are missing.

Examination of urine on Nechiporenko: leukocytes 2500 1 NC; erythrocytes 750 in 1 ml.

Biochemical blood test: whole protein 80 g/l; albumin 56%: globulins α14%; α27%; β13%; γ19%; creatinine 80 µmol/l; urea 6.0 µmol/l; uric acid 250 µmol/l; glomerular filtration 120 ml/min; the tubular reabsorbtion 98%.

Ultrasound of the kidneys and urinary tract: kidneys of normal size and shape, cavity system is not deformed. The concretions are not rendered. The ureters and bladder are not changed.

In/in urography - kidney normal shape and size, cavity system of the kidneys is not changed. The concretions are not defined. Excretory function is not impaired.

Remission after therapy 18 months.

Example 3

And/b No. 1120. Patient C., 43

The diagnosis of Urolithiasis stone in right kidney.

Complains of stabbing pain in the lumbar region to the right with irradiation in the groin area, thigh, painful urination, "red urine", high temperature - 38°C. Sick for about 5 years, when first appeared pain in the lumbar region. Medical help is not sought. About a week ago after exercise appeared stabbing pain in the lumbar region on the right, disa is practical phenomena, change the color of urine. I went to the doctor clinic. Aims to inpatient treatment in therapeutic monitoring.

Objectively: the State of moderate severity. The skin and mucous net. Pastos person. Pulse 88 beats per minute, rhythmic. HELL 140/90. Muffled heart sounds. The vesicular breathing. Tongue coated white bloom. The abdomen is soft. Liver, spleen not palpable. Is palpated painful right kidney. Positive symptom tapping on the lumbar region on the right. Pastos legs.

The wedge. blood analysis: Hb 115 g/l; er. 3,6×1012/l, leukocytes 8,3×109/l; a, paragraph 6, S. 62, HP 23, m 7; ESR 28 mm/hour.

The clinically. urine analysis - Qty - 250,0, muddy, bitter with the "reddish" tint, beats. century 1012, protein 0,33%, no sugar; er. 35-40 in PSR.; leukocytes 20-25 in PSR.; bacteria 200000 1 ml.

Examination of urine on Nechiporenko: leukocytes 6000 in 1 ml; erythrocytes 8500 in 1 ml.

Biochemical blood test: whole protein 74 g/l; albumin 49%: globulins α13%; α28%; β165%; γ25%; creatinine 110 µmol/l; urea 8.3 µmol/l; uric acid 400 µmol/l; glomerular filtration 70 ml/min; the tubular reabsorbtion 96%, uric acid 400 µmol/L.

Ultrasound of the kidneys and urinary tract: kidneys of normal size and shape, cavity system is not deformed. In the pelvis of the left kidney defined 2 concrement in the form hyperechogenic the th rounded education with a diameter of 6 mm and 5 mm The ureters and bladder are not changed.

Review the chest x-ray in the projection of the right kidney are defined shadows suspicious concretions.

In/in urography - buds usually are not changed in size and shape. Abdominal system of the kidneys is not changed, in the pelvis of the right kidney visualized 2 concrement in the form hogenova rounded education with an acoustic shadow in the 6 mm diameter and 5 mm

Hospital patient were treated: avian 2 so 3 times a day, nitroxoline 0.05 g 4 times a day, 2% solution shpy 2-2,0.

On the background of therapy significant change in health status is not marked. Continues to be troubled by pain in the lumbar region, dysuric phenomena, fever.

The wedge. blood analysis: Hb 118 g/l; er. 3,7×1012/l, WBC 8.0×109/l; a, p. 6, S. 61, L.22, m; ESR 25 mm/hour.

The clinically. urine analysis - Qty - 230,0, cloudy, sour 200,0, ADV 1014, protein 0,33%, no sugar; ar-28 in PSR.; leukocytes 18-20 in PSR.; bacteria 100000 in 1 ml.

Examination of urine on Nechiporenko: 5000 leukocytes in 1 ml; erythrocytes 7200 in 1 ml.

Biochemical blood test: whole protein 72 g/l; albumin 50%: globulins α13%; α29%; β14%; γ24%; creatinine 114 µmol/l; urea 8.2 µmol/l; uric acid 410 µmol/l; glomerular filtration 80 ml/min; the tubular reabsorbtion 96%, uric acid 400 µmol/l

Ultrasound of the kidneys and urinary tract: in the pelvis of the left kidney visualized 2 concrement in the form of a hyperechogenic rounded education with a diameter of 6 mm and 5 mm

The lack of positive effect of therapy was the basis for assigning the patient herbal collection, including: the fruits of Juniperus communis l 5,0 (25 g), hops ordinary 11 (55 g), leaves of cowberry 9 (45 g), the herb horsetail 8 (40 g), grass clover medicinal 10 (50 g), grass shepherd's purse 7 (45 g), cornflower blue 6 (30 g), flax seed 12 (60 g), parsley herb 11 (5 5 g), the roots of the madder 7 (3 5 g), lime flowers, 16 (80 g), grass knotweed 9 (45 g), herb Hypericum perforatum 10 (50 g), roots of harrow field 9 (45 g), grass kidney tea 12 (60 g), rhizomes and roots of dagala drug 9 (45 g), anise fruit medicinal 13 (65 g), birch buds 7 (35 g), grass tricolor violet 14 (70 g), fennel fruit 9 (45 g), corn silk 8 (40 g), immortelle flowers sand 6 (30 g), roots and rhizomes of calamus 5 (25 g), licorice root 8 (40 g), the roots of dandelion 7 (35 g), grass, bearberry leaf 5 (25 g), herb wormwood 34 (20 g).

The mixture was ground to a powder consistency, then 2/3 teaspoon was poured on 300 ml of boiling water, insist 15 minutes the mixture stood for, and the patient was taken in a 100 ml three times a day for DV is x months.

After this treatment the patient's condition has improved. No pain in the lumbar region, dysuric phenomena, normal color of urine.

Objectively: the patient's Condition is satisfactory. The skin is clean. Pulse 72 beats per minute, rhythmic. HELL 120/80. Muffled heart sounds. The vesicular breathing, wheezing no. The language clean. The abdomen is soft. Liver, spleen, kidneys are not palpable. Symptom tapping on the lumbar region is negative. No edema.

The wedge. blood analysis: Hb 122 g/l; er. 4,1×1012/l, leukocytes 6,2/109/l; e, 4, pp.62, L.23, m 8; ESR 10 mm/hour.

The wedge. urine analysis - Qty 200,0; straw-yellow, slightly transparent, ADV 1015, no protein, no sugar; erythrocytes 1-3 in PSR.; the leukocyte - 1-2-3 PSR.; bacteria are absent, the cylinders are missing.

Examination of urine on Nechiporenko: leukocytes 3200 1 NC; 1000 erythrocytes in 1 ml.

Biochemical blood test: whole protein 78 g/l; albumin 54%: globulins α14%; α28%; β15%; γ19%; creatinine 80 µmol/l; urea 7.0 mmol/l; uric acid 280 µmol/l; glomerular filtration 114 ml/min; the tubular reabsorbtion 97%.

Ultrasound of the kidneys and urinary tract: kidneys of normal size and shape, cavity system is not deformed. The concretions are not rendered. The ureters and bladder are not changed.

In/in urography - buds usually the second shape and size, abdominal system of the kidneys is not deformed. The concretions are not rendered. The ureters and bladder are not changed.

Remission after therapy 18 months.

Example 4 (prototype)

And/b No. 1382. Patient O., 41

Diagnosis: kidney Stones stones in right kidney.

Complains of stabbing pain in the lumbar region to the right with irradiation in the groin area, thigh, pain during urination, change in color of urine, increased body temperature to 37.8°C. Ill for 5 years, when first appeared pain in the lumbar region, "red urine". Asked for medical help in a hospital, but when the ultrasound examination of the kidneys revealed a stone in the ureter. Took ciston, against which the stone was gone. Further notes aching pain in the lumbar region. Not treated. 10 days ago after a workout in the gym sharply increased pain in the lumbar region to the right, appeared dysuric phenomena, red urine, fever. Sought medical assistance in the hospital, where he was directed to therapeutic monitoring.

Objectively: on admission, the patient's state of moderate severity. Temperature 38,0°C. Skin clean, pastos person. Pulse 86 beats per minute, rhythmic. HELL 135/90. Muffled heart sounds. The vesicular breathing. Tongue coated white bloom. The belly of the correct form, AGCI, actively participates in respiration. Liver, spleen not palpable. Is palpated painful right kidney. Positive symptom tapping on the lumbar region on the right. Pastos legs.

The wedge. blood analysis: Hb 116 g/l; er. 3,7×1012/l, leukocytes 8,5×109/l; a, p 1, p 61, HP 23, m 8; ESR 25 mm/hour.

The clinically. urine analysis - Qty - 250,0, turbid, acid, color "meat slops", UDV, protein 0,33%, no sugar; er. 25-30 in PSR.; leukocytes in 20-30 PSR.; bacteria 200000 1 ml.

Examination of urine on Nechiporenko: 5000 leukocytes in 1 ml; erythrocytes 7500 in 1 ml.

Biochemical blood test: whole protein 78 g/l; albumin 51%: globulins α14%; α27%; β14%; γ24%; creatinine 120 µmol/l; urea 8.0 µmol/l; uric acid 420 µmol/l; glomerular filtration 708 ml/min; the tubular reabsorbtion 96%, uric acid 420 µmol/L.

Ultrasound of the kidneys and urinary tract: kidneys of normal size and shape, cavity system is not deformed. In the pelvis of the right kidney defined 2 concrement in the form of a hyperechogenic rounded education with a diameter of 6 and 5 mm, Ureters and bladder are not changed.

Review the chest x-ray in the projection of the left kidney are defined shadows suspicious concretions.

In/in urography - buds usually are not changed in size and shape. Abdominal system of the kidneys is not treason is a, in the pelvis of the right kidney visualized 2 concrement in the form of a hyperechogenic rounded education with an acoustic shadow, diameter 5 mm

In the hospital the patient were treated: avian 2 so 3 times a day, nitroxoline 0.05 g 4 times a day, 2% solution shpy 2-2,0.

On the background of therapy is not marked positive dynamics in health status, pain in the lumbar region, dysuric phenomena, fever.

The wedge. blood analysis: Hb 115 g/l; er. 3,8×1012/l, leukocytes 8,3×109/l; a, B.1, paragraph 5, S. 62, HP 22, m 8; ESR 23 mm/hour.

The clinically. urine analysis - Qty - 220,0, turbid, acid with a reddish "tint", beats. century 1014, protein 0,33%, no sugar; er. 20-25 in PSR.; leukocytes 20-25 in PSR.; bacteria 100000 in 1 ml.

Examination of urine on Nechiporenko: leukocytes 4500 in 1 ml; erythrocytes 6000 in 1 ml.

Biochemical blood test: whole protein 80 g/l; albumin 52%: globulins α13%; α28%; β14%; γ23%; creatinine 115 µmol/l; urea 8.3 µmol/l; uric acid 410 µmol/l; glomerular filtration 82 ml/min; the tubular reabsorbtion 97%, uric acid 410 µmol/L.

Ultrasound of the kidneys and urinary tract: in the pelvis of the right kidney visualized 2 concrement in the form of a hyperechogenic rounded education diameter 5 mm

Due to the lack of positive effect of therapy the patient is assigned herbal btes is, including grass lavender, spike - 10,0 (50 g); the leaves of the black currant - 10,0 (50 g); birch leaves - 10,0 (50 g); Boudreau plyuschevidnaya - 10,0 (50 g); fruit of Juniperus communis l - 10,0 (50 g); hop cones - 10,0 (50 g); leaves cranberries - 20,0 (100 g); plantain leaves - 28,0 (140 g); fruit strawberry - 60,0 (300 g); horsetail shoots - 60,0 (300 g); grass clover medicinal - 50,0 (250 g); grass shepherd's purse - 15,0 (75 g); cornflower blue - 30,0 (150 g); seed flax ordinary - 40,0 (200 g).

These components were made by 10.0 per 740 ml of boiling water, and boil for 5-6 minutes, insist 2 hours. The mixture the patient has been on a 100 ml three times a day. After removal of stones dose of the mixture was reduced to 5.0, which similarly was poured on 500 ml of boiling water. Herbal collection the patient has been in for two months.

After this treatment the patient's condition has improved, but remained a small aching pain in the lumbar region, pain during urination, frequent urination, appeared heaviness in the epigastrium.

Objectively: the patient's Condition is satisfactory. The skin is clean, remains pastos person. The heart rate of 78 beats per minute, rhythmic. HELL 125/80. Muffled heart sounds. The vesicular breathing, wheezing no. Tongue coated white bloom. The abdomen is soft. Liver, spleen, kidneys are not palpable. Symptom tapping on the lumbar about the Asti to the right slightly positive.

No edema.

The wedge. blood analysis: Hb 120 g/l, Ar,9×1012/l, leukocytes 7,8×109/l; EG B.1, item 5, p.57, L.28, m; ESR 15 mm/hour.

The wedge. urine analysis - Qty 200,0; slightly acid, muddy, ADV 1015, no protein, no sugar; erythrocytes 5-7 in PSR.; the leukocyte - 3-5 PSR.; bacteria 50000 1 mg

Examination of urine on Nechiporenko: leukocytes 4500 1 NC; erythrocytes 1500 in 1 ml.

Biochemical blood test: whole protein 78 g/l; albumin 52%: globulins α15%; α28%; β14%; γ21%; creatinine 116 µmol/l; urea 7.8 µmol/l; uric acid 410 µmol/l; glomerular filtration 83 ml/min; the tubular reabsorbtion 98%.

Ultrasound of the kidneys and urinary tract: kidneys of normal size and shape, cavity system is not deformed. In the pelvis of the right kidney is rendered calculus in the form hogenova rounded education in a diameter of 3 mm.

In/in urography - kidney normal shape and size, cavity system of the kidneys is not deformed. In the pelvis of the right kidney is rendered calculus in the form hogenova rounded education in a diameter of 3 mm. Clinical remission after the treatment is 6 months. Thus, the above extracts from the histories show that the acceptance of the proposed collection of positive effect was obtained in all patients.

In the treatment with the help of the proposed collection (table 1) after okoncane the treatment of established absence of concretions in the kidneys, normalization of laboratory parameters. Data on treatment with the prototype presented in Table 2. The advantage of the proposed collection is the lack of side effects compared with other drugs. There is the removal of calculus from the kidney, the disappearance of inflammatory phenomena, the normalization of the functional state of the kidneys. Remission was observed in patients with increased 2-3 times. In the method prototype remission for 6 months, while treatment with the proposed collection of 18 months.

The treatment for kidney stones, representing the herbal collection, including the fruits of Juniperus communis l, hop cones ordinary, cowberry leaves, the grass of the field hvewa, grass clover medicinal, herb shepherd's purse, cornflower blue, flax seeds, characterized in that it further comprises the parsley herb, the roots of madder, lime flowers, grass knotweed, the herb St. John's wort herb, the roots of harrow field, grass renal tea, rhizomes and roots of dagala medicinal, fruits anise drug, birch buds, grass tricolor violet, fennel fruit, corn stigmas, immortelle flowers sandy, the roots of Acorus calamus rhizome, licorice root, dandelion roots, lekarz the public, grass, bearberry leaf, herb wormwood at the following mass ratio of components:

Juniper fruit3-5
Hop cones9-11
Cranberries, leaves7-9
Horsetail grass6-8
The clover medicinal, herb8-10
Shepherd's bag, grass7-9
Cornflower blue flowers4-6
Flax seed10-12
Parsley, herb9-11
Madder dye, the roots5-7
Linden flowers14-16
Knotweed grass7-9
St. John's wort, herb8-10
The harrow field, roots7-9
Kidney tea, herb10-12
Djagel drug, rhizomes and roots7-9
Anise medicinal, fruit11-13
Birch buds5-7
Viola tricolor, grass12
Fennel fruit7-9
Cornsilk6-8
Sandy immortelle flowers4-6
Air, roots and rhizomes3-6
Licorice root6-8
The dandelion roots5-7
Bearberry common grass3-5
Wormwood, grass2-4



 

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