Paranephric injection method
FIELD: medicine; surgery, nephrology; neurology; clinical pharmacology.
SUBSTANCE: method can be used at injection introductions of medicinal aids into deep layers of soft tissues of lumbar area. Ultrasonic detector is applied to selected area. Area to be found in depth of tissues is detected by means of device on the screen. Different areas of skin are subject to periodical pressing by finger and appearance of wave-shaped reversible changes in skin is observed on screen under point of pressing. Part of skin is marked for injection introduction from which part the deformation wave reaches selected area more precise. Distance from skin to the area is measured and needle is introduced for the depth. 1-1,5 ml of solution is pressed out of syringe. Correctness of introduction is estimated from ultrasonic visualization of localization point which appears in tissues of medicinal infiltrate. Procedure is repeated till correct introduction is performed and that the required medicinal solutions are introduced.
EFFECT: improved precision; prevention of complications.
The invention relates to medicine, in particular to surgery, Nephrology, neurology and clinical pharmacology, and can be used for injectable administration of medications in the deeper layers of the soft tissues of the lumbar region.
The known method Volkova used to blockade the 2nd lumbar sympathetic node, where a patient is put on the table with his back to the doctor, making the blockade, produce anesthesia of the skin 3-4 cm away from the spinous process of the 2nd lumbar vertebra, using a needle, 11-12 cm in length with put on her gum in the form of a disk (lock-timer), placing it perpendicular to the skin, and then pierce the tissue to a depth of 3-4 cm to the rear surface of the transverse process, then the rubber disk on the needle set at 3.5 to 4.5 cm from the surface of the skin, the needle promote parallel to the sagittal plane, above and below the transverse process to the depth marked on the needle with the rubber disk, and in the process of moving the needle to produce a control aspiration syringe, following the absence of the blood, predposylki introduction of novocaine down until it touches the rubber stamp with the skin, then enter 10-15 ml of 1% solution of novocaine, proper introduction which the patient feels the appearance of a pleasant feeling of warmth in the leg (Lobzin SV Puncture and blockade in neurolo the AI. SPb.: Hippocrates - 1999. - S).
The disadvantage of this method is high risk, low accuracy and the narrow scope injecting a solution of a medicinal product. The fact that "blind" piercing the skin of all patients in the same place, namely in the lumbar region at a distance of 3-4 cm from the spinous process of the 2nd lumbar vertebra through the use of needles, 11-12 cm in length causes a wound mechanical damage of parenchymatous organs (kidney, adrenal) pelvis, ureters, aorta or intestines of individuals with anomalies of the kidneys, adrenal glands, or abnormal location of the spinous process of the 2nd lumbar vertebra. In addition, the introduction of the injection needle to a depth of 3.5 to 4.5 cm from the skin surface into the soft tissues of the lumbar region contributes to puncture the parietal peritoneum and the penetrating end of the needle into the abdominal cavity in patients suffering from cachexia or have deformities or deformation defects in the lumbar region. In addition, the method cannot be used in people with significant defects of the spinous process of the 2nd lumbar vertebra, as well as in individuals deprived of the spinous process, or are in the cast, excluding the possibility of determining the location of the spinous process, as well as in children of early age and persons in the besso is a wearable condition, because of the impossibility of assessing the correctness of the drug.
The purpose of the invention is to increase safety, precision injection and expansion of scope.
The essence of the proposed method Nistratov, including anesthesia chosen area of skin, the tissue piercing long injection needle, the control aspiration syringe, following the absence of the blood, predposylki introduction of novocaine, medication and evaluating the appropriateness of the introduction, is that originally put the ultrasonic sensor to the lumbar region, find with it on the screen of the device to the desired site in the depth of the lumbar region, produce periodic pressure with your fingers on different parts of the skin, followed by ultrasound for the appearance of wave-like changes in the structure of the tissue under pressure and thereby determining the possible path and the desired depth of the movement injection needle, choosing the area of skin from which the deformation wave most closely reaches the selected area, and evaluating the appropriateness of introducing is carried dispensed from the syringe 1-1,5 ml of procaine and ultrasonic visualization of locations appearing in the tissues of drug infiltration, after which the syringe is disconnected, connect the second syringe with the required l the drug product and enter it.
In the proposed method by applying ultrasound sensor to the study area of the body is able to visualize the deeper layers, including desired location, regardless of the morphological and anatomical structure of the body, particularly the spine. Due to ultrasound tissue structure with periodic pressure with your fingers on different parts of the skin are able to observe the appearance of a wavy deformation of the tissue, localization which allows to judge the likely path of movement of the injection needle puncture these areas of the skin. Due to the generated reversibly deforming changes in the structure of tissues is possible to accurately choose an area of skin from which the deformation wave most closely reaches the chosen site in the depth of the body regardless of the age of the patient and pathological processes. However, ultrasound is able to accurately determine the distance to this area from the surface of the skin. Subsequent dispensed from the syringe 1-1,5 ml of a solution with simultaneous visualization of the process of formation of drug infiltration allows to evaluate the correctness of the solution. The use of additional syringe allows you to safely and accurately enter additional drug.
Example 1. The patient P. in the age of 1 year with cystic dysplasia of the kidneys, after the actions of the chronic hematogenous osteomyelitis in the absence of the spinous process of the 2nd lumbar vertebra in the conditions of the Nephrology Department was appointed injection analgesic and antispasmodic funds in perirenal tissue of the median region of the kidney. When the blockade by way Volkova after insertion of the needle to a depth of 2.5 cm physician-nephrologist suspected injection injury of the pelvis and refused further application of the method. Applying ultrasonic sensor to the lumbar region revealed on the screen of the device to the desired site in the depth of the lumbar region. Producing periodic pressure with your fingers on different parts of the skin and followed by ultrasound for the appearance of wave-like changes in the structure of the tissue under pressure and thus defining possible way and the depth of the movement of the injection needle, and stopped on a particular area of skin from which the deformation wave is most accurately achieved favorites of the median area of the kidney, and the distance is equal to 2 cm from the skin surface. After making this puncture in the same place and entering the needle to a depth of 2 cm, is dispensed from a syringe 1 ml of novocaine or ultrasonic visualization of the localization appeared infiltrate in perirenal tissue confirmed the correct insertion of the needle. After this introduced an additional 3 ml of novocaine, disconnect the syringe connected to the needle of the syringe with baralgin and brought to 0.5 ml
The way perirenal injections, including Anette is their chosen area of skin, the tissue piercing long injection needle with predposylki the introduction of novocaine, the control in the absence of the appearance of blood in the syringe during aspiration and evaluating the appropriateness of the introduction, characterized in that initially elected to land apply ultrasonic sensor, find with it on the screen of the device the required section in the depth of the tissue, and then produce periodic pressure with your fingers on different parts of the skin, watching on the screen for the appearance of wavy reversible changes in the structure of the tissue under pressure, say for injecting the skin area from which the deformation wave most closely reaches the chosen field, measure the distance to it from the surface of the skin, injected the needle on the depth, extruded from a syringe 1-1,5 ml of the solution, evaluate the correctness of the introduction of ultrasound imaging locations appearing in the tissues of drug infiltration, repeating the procedure until the correct entry, then enter the required medicines.
SUBSTANCE: method involves carrying out epidural block at the level of Th VII-VIII with lidocaine being introduced. Catheter end is caudally moved 1.5-2 cm behind needle bevel, in carrying out epidural block. 1.5% lidocaine solution is administered 6 times a day. Indirect electrochemical blood oxidation is carried out by introducing sodium hypochlorite. 0.06% sodium hypochlorite solution is intravenously introduced in the amount of 400 ml at a rate of 60 drops per 1 min once a day. Enterosgel is additionally introduced in nasogastric way in concentration of 15 g per 100 ml of water 8 h after lesion focus treatment but before starting epidural block repeating the treatment later in 8 h. Intestine peristalsis being observed, enterosgel is introduced per os.
EFFECT: enhanced effectiveness of treatment; early motor and evacuation intestine functions recovery.
FIELD: medicine, urology.
SUBSTANCE: the present innovation deals with means for external application. The suggested gel-like preparation contains hydroxyethylcellulose polymer as a gel foundation, lidocaine hydrochloride, an antiseptic component - benzalconium chloride (50%), gentamycin and water. The remedy is nontoxic and easy in application, it demonstrates no unfavorable side irritating action being of high penetrating capacity of active components.
EFFECT: higher efficiency of application.
1 cl, 1 dwg, 7 ex
FIELD: medicine, pharmacy.
SUBSTANCE: invention relates to the propofol anesthetic composition suitable for parenteral administration. The composition comprises propofol in the concentration from 1 mg/ml to 20 mg/ml, d-alpha-tocopheryl polyethylene glycol-1000 succinate (TPGS) in the concentration from 10 mg/ml to 200 mg/ml, and water. The mass ratio of propofol to TPGS is at least 1:10. The composition is sterilized by final sterilization in autoclave. The present composition overcomes shortcomings of the ready preparative formulation in the emulsion form, namely, it provides the stable clear product in storage under regulated temperature conditions, i. e . in cooling.
EFFECT: improved and valuable pharmaceutical properties of composition.
11 cl, 7 ex
FIELD: organic chemistry, polymers, medicine.
SUBSTANCE: invention describes lidocaine polyacrylate eliciting the prolonged topical anesthetic effect of the general formula: wherein n means (number of links) = 50-70; means a link of polyacrylic acid; means N,N-diethylaminoacetic acid 2,4-dimethylanilide.
EFFECT: valuable medicinal properties of compound.
1 cl, 2 tbl, 1 ex
FIELD: medicine, in particular, equipment for injections and for taking blood or other liquids from organism, which may be also used in laboratories and enterprises in different branches of industry requiring usage of syringes for injecting liquids.
SUBSTANCE: syringe has first part made in the form of cylinder and equipped with first front end including inlet and outlet for liquid and second open end, and second part comprising stem equipped at its front end with piston and at its rear end stop, said second part being positioned for moving between first position wherein stem piston is located at site proximate front end of first part, and second position wherein stem piston is located at site distal from front end of first part. Second part also comprises pusher whose rear end has supporting surface adapted for applying pressure in first axial direction to move second part from second position to first position. First part has at its second end supporting member protruding transverse to first part and made integral therewith. Supporting member has first supporting surface for applying pressure in second axial direction opposite to first axial direction for moving second part from second position to first position, and rear supporting surface for applying pressure in said first axial direction to move second part from first position to second position. Pusher has at its front end two protruding members joined to stem through connecting links so as to define window restricted with stem stop, supporting member of first part, protruding members and rear end of pusher. Protruding members at front end of pusher are terminated with two supporting surfaces for applying pressure in second axial direction to move second part from first position to second position. First part has at least two longitudinal grooves extending from second end of first part to front end and adapted for accommodation of connecting links of pusher. Supporting member of first part has through opening shaped to provide for axial passage of protruding members.
EFFECT: convenient use owing to providing suction and liquid introduction steps for single operation.
17 cl, 7 dwg
FIELD: medical equipment, in particular, devices for injections, formed as syringes containing medicinal substances.
SUBSTANCE: apparatus is formed as syringe with hermetically sealed reservoirs containing different substances, piston mechanism including piston chamber, piston and piston stem. Chamber clearance with continuous internal surface is formed as successively arranged reservoirs or sectors with different diameters or sections, with one of reservoirs being formed as piston cylinder. Piston chambers are hermetically separated within piston chamber clearance further than line of transition of smaller diameter or other section by movable device.
EFFECT: simplified construction.
2 cl, 5 dwg
FIELD: medicinal equipment, in particular, safety syringes.
SUBSTANCE: safety syringe has cylinder with axial through opening, retainer provided within front end of cylinder, piston, needle hub, and needle. Piston positioned for sliding inside cylinder is equipped with sealing rubber member, head and flange disposed on piston in opposed relation to head. Needle hub is detachably engaged with cylinder and is provided with axial opening corresponding to that of cylinder and communicated therewith, and feeding opening adapted for communication with axial openings of needle hub and cylinder and for providing insertion of piston head. Needle has sleeve engaged with front head part of needle hub, and metal pipe engaged with sleeve. Piston has neck portion defined at its front end and arranged so that rubber sealing member tightly adheres thereto, and spatially inclined teeth. Head is made conical. Needle hub has conical front end with protrusions mating with cylinder retaining device upon rotation of cylinder. Slots are provided for engagement with inclined teeth. Bead provided in peripheral portion of feeding opening is mating with piston conical head. Protrusions are released from finger clamps upon rotation, when inclined teeth are engaged with slots.
EFFECT: simplified construction and convenient use.
4 cl, 12 dwg
FIELD: medical engineering.
SUBSTANCE: device has sealed reservoirs, containing substances, and piston mechanism, having piston cylinder, piston and piston rod. Device for moving liquid between the reservoirs is mounted in piston cylinder lumen. The device has separating piston and compression unit arranged in series. The unit designed as casing or carcass is mounted in projection of its external cylindrical part along the perimeter. Hollow internal lumen of has exit to piston projection inward from its external perimeter. The separating piston makes two connections with the piston cylinder and compression unit at the same time. The separating piston is movable into compression unit lumen with compression or change in shape taking place at the same time. The compression unit allows to make communication between reservoirs.
EFFECT: simplified design.
5 cl, 8 dwg