Acaricide
FIELD: agriculture.
SUBSTANCE: invention relates to acaricidal agent containing (mass %): alpha-cypermetrin 0.15-0.25; imiprotrin 0.10-0.35; N-octylbicycloheptadicarboximide 0.8-1.2; triethylene glycol 1.0-2.0; solvent 43.0-50.0; and balance: hydrocarbon propellant.
EFFECT: acaricide of increased effectiveness against red ticks (Rhipiceplalus everti).
2 cl, 4 tbl
The invention relates to a tool for the control of mites and ixodid ticks, which are insect parasites that transmit dangerous diseases, in particular for aerosol acaricide means based on pyrethroids, and is intended to protect people from ixodus bloodsucking ticks (class Chelicerata, order Parasitiformes, family Ixodidae). Ticks are carriers of pathogens of many dangerous diseases of viral, bacterial and protozoal etiology and consequently have significant epidemiological importance. For the Russian Federation the most dangerous diseases, transmitted by ixodid ticks, are tick-borne encephalitis, Ixodes tick-borne borreliosis and Crimean-Congo hemorrhagic fever.
Pyrethroids are divided into two groups. I pyrethroids include pyrethrins, permethrin, tetramethrin, bioallethrin, resmethrin, phenothrin, etc. all of these compounds are the Central component of SOON2and they are from insects hyperactivity, tremor, and then the knockdown. Pyrethroids group II - cypermethrin, deltamethrin, fenvalerate etc. all of these compounds are the Central component COOCHCN-and they are from insects hyperactivity, loss of coordination, seizures, irreversible knockdown.
Known acaricidal spray product containing imiprothrin is or its mixture with other PYRETHROID-based cyclopropanecarboxylate or chrysanthemate, one or more substances that enhance the action of PYRETHROID compounds selected from piperonylbutoxide, octachlorodipropyl ether, N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo/2,2,2/Oct-5-ene-2,3-dicarboximide, isobornyl-tizianasat, N-(2-ethinyl)-bicyclo/2,2,1/hept-5-ene-2,3-dicarboximide. The tool may also contain a surfactant, such as polyoxypropyleneglycol, 1,3-butyleneglycol and others, corrosion inhibitor, an organic solvent, such as isopropyl alcohol, water and hydrocarbon propellant (EN 2162635 C2, 10.02.2001).
Being an effective means of dealing with a wide range of harmful insects, living in homes and on the street, including pet ticks, such as Pyroglyphidae (for example, Dermatophagoidae farinae hughes, Dermatophagoides pteronyssinus), Acaridae (e.g., Tyrophagus putrescentiae, Aleuroglyphus ovatus), Glycyphagidae (such as Glycyphagus privatus, Glycyphagus domesticus), Cheyletidae (for example, Cheuletus Fortis, Chelacaropsis moorei baker), Tarsonemidae, Cryptostigmata, and seobythesea mites, such as Ornithonyssus bacoti, Ornithonyssus sylviarum, Dermanyssus gallinae, Ixodides, the foregoing known acaricidal agent is not effective against ticks Hyalomma vectors of pathogens congorama hemorrhagic fever (KGL), tick-borne encephalitis (TBE), Ixodes tick-borne borreliosis (IKB) and other hazardous natural focal diseases when processing the top the service.
The closest to the invention is acaricidal agent (EN 2226055, 27.03.2004)containing the following components in the following amounts, wt.%:
imiprothrin | 0,04-0,40 |
cypermethrin | of 0.10 to 1.0 |
N-activitylogoptions | 0,40-4,0 |
the isobutane fraction or | |
hydrocarbon propellant | 40,0-60,0 |
kerosene | the rest of it. |
This tool is inefficient for large and relatively resistant to acaricides ticks of the genus Hyalomma, it is only effective against smaller and more sensitive to acaricides ticks of the genus Ixodes, in particular Ixodes persulcatus is the main vector of tick-borne encephalitis virus and Borrelia burgdorferi Ixodes tick-borne borreliosis.
Technical problem on which this invention is directed, is the achievement of effective acaricide means against Ixodes ticks above the genus Hyalomma marginatum.
The technical problem is solved due to the fact that aerosol acaricidal agent, including imiprothrin, another PYRETHROID compound, the amplifier action of a PYRETHROID compound is N-activitylogoptions, Ernesto-active substance (SAS) - triethylene glycol, the solvent and hydrocarbon propellant, as another PYRETHROID means contains-cypermethrin at the following content, wt.%:
Alfa-cypermethrin | 0,15-0,25 |
imiprothrin | 0,10-0,35 |
N-activitylogoptions | 0,8-1,2 |
triethylene glycol | 1,0-2,0 |
solvent | 43,0-50,0 |
the hydrocarbon propellant | rest |
In addition, the tool may contain a corrosion inhibitor in an amount of 0.01 to 0.05 wt.%.
To obtain acaricide means according to the invention used the following substances:
Imiprothrin - 2,5-dioxo-3-(prop-2-inyl)-1-imidazolidin-1-ylmethyl(1R)-CIS, TRANS-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate.
The structural formula is:
This PYRETHROID synthesized and patented by the Japanese company Sumitomo chemical". In Russia registered substance (premix) Pralle (50% of imiprothrin) for the production of insecticidal agents ("List of domestic and foreign disinfectants permitted for use on the territory of the Russian Federation" next "List..." - No. 0045-99).
Alphacypermethrin is - widely used PYRETHROID group II. It is a mixture of two isomers of cypermethrin - 1R-CIS S - and 1R-CIS-R-α-cyano-3-phenoxybenzyl-3-(2,2-dichloro-vinyl)-2,2-dimethylcyclo-propanecarboxylate in a 1:1 ratio.
The structural formula is:
Alfa-cypermethrin is a white crystalline substance with a melting point 78-81°With density d=1.28 g/cm3, low volatile (vapor pressure of 1.7×10-7mm Hg at 20°). Almost nerastvorim in water, soluble in aromatic and polar organic solvents. The substance is unstable when heated above 80°and in an alkaline environment.
Alfa-cypermethrin (96%technical) production company "Wrotham India Ltd. (India) registered as an insecticidal substance ("List of..." no 0060-02).
As the surfactant used triethylene glycol (TU 6-01-5-88).
Corrosion inhibitor choose any well-known, for example, Revocare AC 28 (diethanolamide fatty acids) or Revokers In 2045 (dodecenyl succinic anhydride) production company "Witeo Surfactants GmbH (Germany).
MGK-264 - N-activitylogoptions (the drug company MGK, USA), synergist, i.e. the amplifier action of PYRETHROID compounds.
Used as a solvent isopropyl alcohol, dehydrated (GOST 9805-4), and can also be used and other alcohols, including ethanol, and other solvents such as kerosene Devdariani.
As hydrocarbon propellant use hydrocarbon propellant for aerosol packaging (TU 39-892-93 or THE 38-401-16-92) or isobutane fraction (TU 0272-025-00151638-99), or other known propellant.
Preparation of the proposed acaricide tools
Preparation of the product is carried out in a reactor with a capacity of 5 m3with a steam jacket heating and agitator.
In the reactor, tested for purity, purged with an inert gas, from the site of production preparation served estimated number of primary solvent incorporated in the formulation, such as isopropyl alcohol.
Next, load a pre-weighed amount of MGK, then alphacypermethrin. Include a stirrer, stirred for 15-20 minutes at a temperature of 20-25°until complete dissolution of alphacypermethrin.
Further, when operating the mixer load pre-weighed quantity pralle, triethylene glycol, corrosion inhibitor, Revocare.
The solution is stirred for 45-60 minutes until complete dissolution of the components, then switched off the stirrer select the sample for analysis to verify the quality of the finished product.
Then the product when operating the mixer pump through Phil is the Tr is fed to the filling line.
Table 1 shows the dose filling aerosol cans acaricide tool according to this invention.
Table 1 | ||
Name of the component | By weight | Volume |
1. Product | 49,0±3 | 88,45 |
2. Propellant | 49,0±2 | 61,55 |
TOTAL | 98,0±5 g | 150,0 |
Table 2 shows the formulation of the proposed tools.
Table 2 | |||
Name of the component | Content, wt.% | ||
1 | 2 | 3 | |
1. Alfa-cypermethrin | 0,16 | 0,20 | 0,23 |
2. Imiprothrin | 0,20 | 0,16 | 0,33 |
3. MGK 264 | 1,2 | 1,0 | 0,8 |
4. Triethylene glycol | 2,0 | 1,5 | 1,0 |
5. Corrosion inhibitor - Revokers as-28 | - | 0,03 | 1,7 |
6. Isopropyl alcohol absolutized | 47,0 | 45,0 | 43,0 |
7. Hydrocarbon propellant | 49,44 | 50,98 | 52,94 |
The biological activity of the proposed drug studied in the natural foci of hemorrhagic fever and semi-arid regions of the Stavropol territory) and the combined foci of tick-borne encephalitis and Lyme borreliosis agents (forest districts of the Tyumen region and Altai territory).
The claimed means for all three formulations were applied to the trousers of cotton or mixed fabrics with a consumption rate of 24 s/m2. Hungry active females of different species were placed on the bottom of the pants and record the time of occurrence of the state of knockdown and alienation bottoms with trousers (Tcf), the maximum lifting height on fabric (MVcf), counting from the level of the ankle. Between experiments pants hung in the laboratory. Efficacy trials were conducted after 1, 3 and 7 days after treatment.
Table 3 shows acaricidal activity of formulations of funds, are given in table 2, aerosol against ticks Hyalomma marginatum (Stavropol region).
Table 3 | ||||||
Recipe № | Acaricidal activity | |||||
1 day | 3 day | day 7 | ||||
MVcfcm | Tcf, min | MVcfcm | Tcf, min | MVcfcm | Tcf, min | |
1 | 48,2±1,2 | 3,9±0,2 | 52,4±1,6 | 4,2±0,1 | >100,0 | >8,0 |
2 | 45,4±1,2 | 3,8±0,2 | 50,2±1,6 | 4,0±0,1 | >100,0 | >8,0 |
3 | 43,8±1,2 | 3,5±0,2 | 48,4±1,6 | 3,7±0,1 | >100,0 | >8,0 |
When comparative tests of funds by recipe No. 2) and means - the closest analogue is found that the maximum lifting height of the tick that the treated tissue, respectively 20,2 cm and 78.5 cm, and the time lapse with this fabric - 2,3 min and 9.5 min, respectively.
Table 4 shows the comparative acaricidal activity of the various funds aerosol in respect of Ixodes persulcatus (Tyumen oblast, Altai Krai).
Table 4 | |||||||
The name means | Operating the substances | Acaricidal activity | |||||
1 day | 3 day | day 7 | |||||
MVcfcm | Tcf, min | MVcfcm | Tcf, min | MVcfcm | Tcf, min | ||
The inventive tool | Alfa-cypermethrin, imiprothrin (Retz. No. 2) | 8,72±0,16 | 1,08±0,03 | 28,21±0,64 | 3,36±0,05 | 36,27±0,61 | 3,57±0,08 |
Tool No. 1 | Alfa-cypermethrin | 22,64±0,61 | 3,00±0,08 | 28,91±0,59 | 3,57±0,09 | 35,20±0,54 | 4,33±0,06 |
Tool No. 2 | alphamethrin permethrin | 28,3±0,1 | of 3.46±0,1 | 33,3±0,3 | 3,54±0,4 | 40,9±0,3 | 4,18±0,1 |
Tool No. 3 | alphamethrin diethyltoluamide | 28,0±0,2 | 3,41±0,1 | 33,2±0,2 | 3,52±0,2 | 41,0±0,4 | 421±0,2 |
The test results showed that for the first time received acaricidal agent that is highly EF is aktivnosti against ticks Hyalomma marginatum along with high efficacy against ticks of the genus Ixodes.
Declare acaricide tool aerosol is designed for use on clothing. It provides the necessary level of protection of humans from ticks of both genera (Hyalomma and Ixodes). The performance indicators for 3 days correspond to required level: average time of occurrence of a knock-down from ticks (BHcf) not more than 5.0 minutes; maximum lifting height on the treated tissue (MVcf) no more than 50,0 see the Time on the ground in this case corresponds to the time lapse mites on the treated fabric.
The results of the tests in Siberia showed that this tool is highly effective and in respect of the taiga and forest-ticks - major vectors of pathogens EC and IKB in Russia: CT about 1 minute; Nmaxless than 10 cm; after contact with treated cloth, all ticks are killed on the host, not having stuck. Thus, it is proved that the acaricide the agent has activity, which significantly exceeds the requirements for this group of drugs: KT less than 5 minutes; Nmaxnot more than 50 cm; KSP<1.
1. Acaricidal agent, including imiprothrin, another PYRETHROID compound, the amplifier action of PYRETHROID compounds - N-activitylogoptions, triethylene glycol, the solvent and hydrocarbon propellant, characterized in that the qualities of the other PYRETHROID means contains Alfa-cypermethrin, in the following, wt.%:
Alfa-cypermethrin | 0,15-0,25 |
Imiprothrin | 0,10-0,35 |
N-activitylogoptions | 0,8-1,2 |
Triethylene glycol | 1,0-2,0 |
Solvent | 43,0-50,0 |
The hydrocarbon propellant | Rest |
2. The tool according to claim 1, characterized in that it further comprises a corrosion inhibitor in an amount of 0.01 to 0.05 wt.%.
FIELD: organic chemistry.
SUBSTANCE: invention describes C2-phenyl-substituted cyclic ketoenols of the general formula: wherein W means hydrogen atom, alkyl with 1-6 carbon atoms; X means alkyl with 1-6 carbon atoms, alkenyl with 2-6 carbon atoms; Y means hydrogen atom, methyl, ethyl, isopropyl, alkenyl with 2-6 carbon atoms, ethynyl; Z means hydrogen atom, alkyl with 1-6 carbon atoms under condition that at least one of residues W, X, Y or Z means a chain with at least 2 carbon atoms but only one of residues X and Y can mean alkenyl with 2-6 carbon atoms; CKE means one of the following groups:
,
,
and
wherein A means hydrogen atom, alkyl with 1-6 carbon atoms; B means hydrogen atom, alkyl with 1-6 carbon atoms; A and B in common with carbon atom to which they are bound mean cycloalkyl with 5-6 carbon atoms wherein the ring carbon atom can be substituted with oxygen atom and can be substituted with alkyl with 1-6 carbon atoms or alkoxyl with 1-6 carbon atoms; A and B in common mean group of the formula:
D means hydrogen atom or phenyl substituted with fluorine atom if CKE means group of the formula (4); G means hydrogen atom (a) or one of groups of the formula:
or
wherein R1 means alkyl with 1-6 carbon atoms, alkoxymethyl with 1-2 carbon atoms; R2 means alkyl with 1-4 carbon atoms; A and Q1 in common mean alkanediyl with 3-4 carbon atoms; Q2 means hydrogen atom. Invention provides preparing compound of the formula (I) possessing with insecticide, acaricide and herbicide activity.
EFFECT: valuable properties of compounds.
2 cl, 8 tbl, 32 ex
FIELD: organic chemistry.
SUBSTANCE: invention describes C2-phenyl-substituted cyclic ketoenols of the general formula: wherein W means hydrogen atom, alkyl with 1-6 carbon atoms; X means alkyl with 1-6 carbon atoms, alkenyl with 2-6 carbon atoms; Y means hydrogen atom, methyl, ethyl, isopropyl, alkenyl with 2-6 carbon atoms, ethynyl; Z means hydrogen atom, alkyl with 1-6 carbon atoms under condition that at least one of residues W, X, Y or Z means a chain with at least 2 carbon atoms but only one of residues X and Y can mean alkenyl with 2-6 carbon atoms; CKE means one of the following groups:
,
,
and
wherein A means hydrogen atom, alkyl with 1-6 carbon atoms; B means hydrogen atom, alkyl with 1-6 carbon atoms; A and B in common with carbon atom to which they are bound mean cycloalkyl with 5-6 carbon atoms wherein the ring carbon atom can be substituted with oxygen atom and can be substituted with alkyl with 1-6 carbon atoms or alkoxyl with 1-6 carbon atoms; A and B in common mean group of the formula:
D means hydrogen atom or phenyl substituted with fluorine atom if CKE means group of the formula (4); G means hydrogen atom (a) or one of groups of the formula:
or
wherein R1 means alkyl with 1-6 carbon atoms, alkoxymethyl with 1-2 carbon atoms; R2 means alkyl with 1-4 carbon atoms; A and Q1 in common mean alkanediyl with 3-4 carbon atoms; Q2 means hydrogen atom. Invention provides preparing compound of the formula (I) possessing with insecticide, acaricide and herbicide activity.
EFFECT: valuable properties of compounds.
2 cl, 8 tbl, 32 ex
FIELD: agriculture.
SUBSTANCE: claimed fungicide composition contains iprodione and vegetable-origin oil having increased drying ability and iodine number of above 90. Weight ratio of oil/iprodione is from 0.15 to 1.6. Treatment method includes application of effective and non-phytotoxic amount of composition onto plant overground parts.
EFFECT: composition of decreased phytotoxicity.
8 cl
FIELD: biotechnology.
SUBSTANCE: claimed composition contains (mass %): sodium lignogumate 0.5-1; hydropterine 0.5-1; and balance up to 100 %: water.
EFFECT: increased yield per unit; agriculture production of improved quality.
3 ex, 4 tbl
FIELD: organic chemistry, pesticides.
SUBSTANCE: claimed composition represents mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, wherein carvacrol and thymol compound/zinc ratio is from 60:40 to 65:35. Also described is pesticide composition containing mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, and at least one carrier, wherein weight ratio of carvacrol to thymol is 10:1. Claimed method for parasite controlling includes step of composition blending with carrier and application thereof onto target area.
EFFECT: composition for pest controlling and prevention of contamination with pests such as insect, mite, fungi or parasites.
FIELD: organic chemistry, pesticides.
SUBSTANCE: claimed composition represents mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, wherein carvacrol and thymol compound/zinc ratio is from 60:40 to 65:35. Also described is pesticide composition containing mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, and at least one carrier, wherein weight ratio of carvacrol to thymol is 10:1. Claimed method for parasite controlling includes step of composition blending with carrier and application thereof onto target area.
EFFECT: composition for pest controlling and prevention of contamination with pests such as insect, mite, fungi or parasites.
FIELD: organic chemistry, pesticides.
SUBSTANCE: claimed composition represents mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, wherein carvacrol and thymol compound/zinc ratio is from 60:40 to 65:35. Also described is pesticide composition containing mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, and at least one carrier, wherein weight ratio of carvacrol to thymol is 10:1. Claimed method for parasite controlling includes step of composition blending with carrier and application thereof onto target area.
EFFECT: composition for pest controlling and prevention of contamination with pests such as insect, mite, fungi or parasites.
FIELD: organic chemistry, pesticides.
SUBSTANCE: claimed composition represents mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, wherein carvacrol and thymol compound/zinc ratio is from 60:40 to 65:35. Also described is pesticide composition containing mixture of carvacrol and thymol compounds with salt of transition metal, namely zinc, and at least one carrier, wherein weight ratio of carvacrol to thymol is 10:1. Claimed method for parasite controlling includes step of composition blending with carrier and application thereof onto target area.
EFFECT: composition for pest controlling and prevention of contamination with pests such as insect, mite, fungi or parasites.
FIELD: organic chemistry, insecticides.
SUBSTANCE: invention describes dialkylamide derivatives of pyrethroid acids of the general formula (III): wherein R1 and R2 represent organic radicals and each radical represents ethyl, or they both can be bound and in common with nitrogen atom represent piperidide, hexamethyleneimide, morpholide. Represented compounds are used as chemical agents for control of insect-pests in agriculture, veterinary science and cattle breeding.
EFFECT: valuable properties of compounds.
2 dwg, 4 ex
FIELD: agriculture.
SUBSTANCE: invention relates to composition containing pirimetanyl and phosetyl-Al in weight ratio of 0.05-10 and method for healing and prophylaxis controlling of plant phytopathogenic organisms using the same. Application of phosetyl-Al to prolong pirimetanyl action also is described.
EFFECT: decreased treatment process number which is necessary to control disease progress.
8 cl, 1 ex
FIELD: insect controlling methods.
SUBSTANCE: claimed granulate contains (wt.%): deltamethrin 5-60; damping agent 5-15; dispersant 10-30; solid inert substance selected from group containing talc, bentonites, lime, loess, chalk, clay, dolomite, infusorial earth, calcium sulfate, magnesium sulfate, magnesium oxide, magnesia, milled plastics and resins, attapulgite, montmorillonites, vermiculites, mica, ground or milled corn, ground wood or sawdust, ground or milled bark, ground nut shell or cellulose, one or more acids in amount to maintain pH 1-7, wherein total sum of ingredients is 100 %.
EFFECT: preparation for cockroach controlling of improved effectiveness.
7 cl, 10 ex
FIELD: agrochemistry.
SUBSTANCE: invention provides a stable aqueous formulation of hydrophobic pesticide by emulsifying aqueous phase and a water-immiscible phase, the former containing poly(alkylene glycol) ether and the latter hydrophobic pesticide and one or several emulsifiers selected from group including carboxylate, sulfate, sulfonate, alcohol solutions of ethoxylated and alkylphenolethoxylate, fatty acid ethyl ester, sorbitol ester, ethoxylated fat or oil, aminoethoxylate, ethylene oxide/propylene oxide copolymer, fluorocarbon, and siliceous polymer.
EFFECT: increased stability of formulations.
38 cl, 1 tbl, 12 ex
FIELD: plant protection.
SUBSTANCE: method is characterized by that grain-crops in vegetation phase are treated with mixture of methylheptenone with Deciss taken at volume ratio (1-5):1.
EFFECT: reduced toxic pesticide loading on plants in vegetation phase.
1 tbl



