Method for cosmetic rehabilitation of skin tissues in post-operating and other posttraumatic conditions (variants)

FIELD: cosmetology, esthetic surgery, applied biopharmacology.

SUBSTANCE: invention relates to medicative and cosmetic agents, and uses of biologically active substances based on natural biological complexes. Claimed method includes application of Mirralgin balm having analgesic, anti-inflammation and resolving action, Reventon balm, having vessel restorative action, for edema reducing and microcirculation improving. In process of blepharoplastic eye boundary bandage microemulsion having recovery and animative action on eaves skin is applied, and in process of facelifting cream mask having bactericide, vessel restorative and recovering action, and enhancing of local immunity is applied. Mirralgin balm and Reventon balm treatment is carried out sequentially or alternatively. In another embodiment after skin cleaning and treatment of damaged zone with anti-septic agent Bacteriophage gel, which disinfects skin surface, prevents biofilm forming, accelerates cicatrizing process is applied, then posttraumatic zone is treated with cleaning milk, toned up with tonic lotion and cream mask having bactericide, vessel restorative and recovering action, and enhancing of local immunity is applied.

EFFECT: method for skin structure recovering without skin trauma.

4 cl, 7 ex, 1 tbl

 

The invention relates to cosmetology, cosmetic surgery, health, beauty and Wellness, applied biopharmacology, as well as the use of biologically active substances based on natural biological complexes in therapeutic and cosmetic purposes.

Skin restoration, the quality of its characteristics in the postoperative period, after a variety of traumatic events (injury, accident, accidents, burns, mesotherapy, surgery for a sex change, and others) is very important.

Achieving a positive result after carrying out aesthetic surgery for tissue has a rehabilitation period. On the aesthetic procedure is chosen by people with different types and skin conditions. Flabby skin, for example, is characterized by inadequate blood supply of the dermis and reduced biosynthesis therefore, the period of recovery is more prolonged (E. Hernandez, A. Margolin, A. Petrukhina Lipid barrier of the skin and cosmetic products. Publishing project "Department", M., 2003). A relatively young skin may have violated the lipid barrier and reduced local immunity, therefore, its recovery may be accompanied by infection. The condition of the skin after aesthetic surgery is characterized by inflammation: swelling, redness, pain, fever, secretion of mediators, often accompanied by infection, not the full-speed regeneration, scar formation, persistent erythema, pigmentation disorders and other (Fingers M.A., Ivanov A.A., Severin S.E. Intercellular interaction. M.: Medicine, 2003).

Known way to restore the skin on the face, in which a positive result achieved by the introduction of epidermal acid vitamin a (U.S. patent No. 4603146, publ. 1986).

The disadvantage of this method is low efficiency and duration of the process, and the subsequent recovery of the skin after mesotherapy.

The closest in technical essence of the present invention is a method of treatment of cosmetic defects of the skin, including the application of funds (RF patent No. 2114614, BI No. 19, 1998).

The disadvantages of this method skin rehabilitation in the postoperative period is that the tool is used that contains phenol, which is toxic to patients requiring follow-up tissue repair, as well as the inability to use this method sparingly rehabilitation tissues.

Object of the present invention is to provide an efficient method for the rehabilitation of the skin tissue in the postoperative period of the surgery or other traumatic conditions.

As a result of use of the present invention gentle action on the skin tissue during rehabilitat and after cosmetic surgery or other traumatic conditions, reduces the risk of skin complications in the early postoperative period is significantly shorter rehabilitation period, significantly improved clinical effect aesthetic surgery, through the use of effective therapeutic and cosmetic company "Mirra-M, containing biologically active substances based on natural biological complexes on the background light massage in plastic surgery after postoperative rehabilitation care of the skin and help reduce swelling, redness, bruising and pain, to restore the protective functions of the skin tissue, stimulates the process of repair and regeneration, bactericidal and resolving action, providing a more rapid elimination of post-traumatic phenomena.

When using the proposed method restores the skin's structure, its quality characteristics, without hurting the skin, and does not require subsequent recovery.

The above result is achieved by a method of cosmetic rehabilitation of the skin tissue in the postoperative period and other post-traumatic conditions, including the use of therapeutic and cosmetic products from the 2nd to 4th day after cleansing and treatment of the damaged zone antiseptic applied the balm Merrilyn with analgeziruushim, anti-inflammatory and Russ is yuushin action 3-4 times a day and massage gently for 5 minutes, then as hematomas from 4 to 10 day put balm Reventon with vessel restorative action to help reduce swelling and improves microcirculation, 2-4 times a day and massage gently for 5 minutes until completely absorbed, in accordance with the nature of the traumatic condition of the tissue, with blefaroplastia put a microemulsion "Eye contour-band"with restorative, revitalizing effect on the skin of the eyelids, light massage in a circular motion, and when the facelift apply the cream-mask "Mind"with bactericidal, vessel restorative, regenerating effect and improves local immunity.

When the facelift in addition to treatment cream mask "Mind" on the face, neck and chest massages, starting from the back of the neck is going to face, neck and décolleté, alternating movements, stroking, rubbing and kneading, and the massage is carried out after the removal of the stitches in a sparing mode.

Processing balm, Merrilyn conduct alternately with balsam Reventon first balm, Merrilyn, then balm Reventon.

In another embodiment, the method cosmetic rehabilitation of the skin tissue in the postoperative period and other post-traumatic conditions, including the use of medical-cosmetic products, from 1st to 6th day after the cleansing is of the damaged area applied Bacteriophage-gel, which disinfects the surface of the skin, prevents the formation of biofilms, thereby accelerating the healing process, for 10-15 minutes until the disappearance of bruising and swelling and relieve the inflammatory process, then applied the balm Reventon with vessel restorative action to help reduce swelling and improves microcirculation, 2-4 times a day for 5 minutes until completely absorbed light massage movements, in accordance with the nature of the traumatic condition in surgery on the face, from 7 to 14 day cleanse posttraumatic area milk cleanser, then tone up lotion-tonic, and then apply the cream-mask of the Mind"with bactericidal, vessel restorative, regenerating effect and improves local immunity.

When surgery on the face in addition to treatment cream mask "Mind" on the face, neck and chest massages, starting from the back of the neck is going to face, neck and décolleté, alternating movements, stroking, rubbing and kneading, and the massage is carried out after the removal of the stitches in a sparing mode.

Processing the Bacteriophage-gel carried out alternately with the balm Reventon first Bacteriophage-gel, then balm Reventon.

The way cosmetic rehabilitation of the skin tissue in the postoperative period and other post-traumatic conditions carry out the following manner.

2 to 4 day after cleansing and processing antiseptic damaged area applied the balm Merrilyn with analgeziruushim, anti-inflammatory and absorbing effects, containing emulsion complex of grape, milk Thistle, licorice root extract, a complex of polyunsaturated fatty acids on the basis of fish oil and vitamin F, essential oils of clove, cypress, monarda, peppermint, tea tree, sage, eucalyptus, beta-carotene, 3-4 times a day and massage gently for 5 minutes. Then as hematomas from 4 to 10 day put balm Reventon with vessel restorative action to help reduce swelling and improves microcirculation, which contains extracts of Arnica, horse chestnut, licorice, clover, complex of essential oils, 2-4 times a day and massage gently for 5 minutes until completely absorbed.

In accordance with the nature of the traumatic conditions, for example when blefaroplastia additionally put "Eye contour-band"with revitalizing (regenerating, quickening) effect on the skin of the eyelids, light massage with circular motions, containing gomogenizirovannogo caviar salmon, complex vegetable and essential oils, light massage in a circular motion.

When the facelift apply the cream-mask "Mind", the United which has a regenerating effect, contains grape, milk Thistle, essential oils of monarda, lavender, geranium, tea tree, beta-carotene, ascorbyl palmitate, gomogenizirovannogo caviar of sturgeon fishes, vitamin F.

When applying the cream-mask "Mind" on the face, neck and décolleté carried out on a cream-mask "Mind" massage, starting from the back of the neck is going to face, neck and décolleté, alternating movements, stroking, rubbing and kneading, and the massage is carried out after the removal of the stitches in a sparing mode.

Processing balm, Merrilyn with balsam Reventon can be performed sequentially, first with the balm of Merrilyn, then balm Reventon.

In another embodiment of the method after cleansing, damaged zones 1 through 6 day on it put a Bacteriophage-based gel that sanitizes the surface of the skin, prevents the formation of biofilms, thereby accelerating the healing process, containing bacteriophages in the form of a purified concentrate, carbopol, sodium benzoate, extracts of clover, yarrow, clover, licorice, lavender essential oil, clove, myrrh, water, in the form of applications for 10-15 minutes. Bacteriophage-gel applied daily until complete disappearance of inflammation, bruising and swelling. Then apply the balm Reventon for 5 minutes until completely absorbed light massage movements. In accordance with the nature of the traumatic condition in Opera the AI on the face 7 to 14-day clean cotton swabs posttraumatic area cleansing milk, containing extract of lime flowers, cetol, emulgin, vitamin E, fragrance composition, Katon, then her tone, lotion, tonic, containing grains of fucus puzyrchatogo (sea oak), concentrate, kelp sugary, chitosan, citric acid and Katon with a pH of 6.0, and then apply the cream-mask "Mind" and carried out on a cream-mask "Mind" massage, starting from the back of the neck is going to face, neck and décolleté, alternating movements, stroking, rubbing and kneading, and the massage is carried out in a sparing mode after removing joints.

Processing the Bacteriophage-gel carried out alternately with the balm Reventon first Bacteriophage-gel, then balm Reventon.

A number of tools for processing of the damaged zone is selected depending on the surface to be treated.

For rehabilitation of the fabrics in the early postoperative period and at different post-traumatic phenomena used the following tools company MIRRA-M".

Balm transdermal "Merrilyn" - to prevent nonspecific inflammation and pain, has analgesic and resolving action due to the complex of essential oils on areas of bruising. It consists of emulsion complex of grape, milk Thistle, licorice root extract, a complex of polyunsaturated fatty acids on the basis of fish oil and vitamin F, the air is some oil of cloves, cypress, monarda, peppermint, tea tree, sage, eucalyptus, beta-carotene Balm, and helps restore the skin.

Balm "Reventon" - contains extracts of Arnica, horse chestnut, licorice, sweet clover, a complex of essential oils. The balsam has a vessel strengthening, reparative and anti-inflammatory effect, helps to restore the quality characteristics of skin tissue, reduce swelling and increase circulation.

Cream mask "Mind" - contains grape, milk Thistle, essential oils of monarda, lavender, geranium, tea tree, beta-carotene, ascorbyl palmitate, gomogenizirovannogo caviar of sturgeon fishes, vitamin F. Cream mask bactericidal, vessel strengthening, regenerating effect and improves local immunity (RF patent No. 2232587 registered 20.07.04).

The microemulsion "Eye contour-bandage - contains gomogenizirovannogo caviar salmon, a complex of plant and essential oils. The microemulsion has a revitalizing effect (restores, revitalizes the skin of the eyelids, removes puffiness, provides nourishment and protection to the skin (patent RF №2232587 registered 20.07.04).

Bacteriophage-gel - gel dosage form of medical immunobiological preparations with bacteriophage containing bacteriophages in the form of a purified concentrate, carbopol, sodium benzoate, extras the points of clover, yarrow, clover, licorice, lavender essential oil, clove, myrrh, water, the effect of anti-inflammatory therapy is achieved by the application and fixation of the gel over time on the skin surface, which gives the possibility of prolonged action. Bacteriophage-gel ensures a uniform distribution of phage particles, increasing the effectiveness of the treatment, a uniform distribution of phage particles, increasing the effectiveness of the treatment, has a bactericidal action. BioFach-gel disinfects the surface of the skin, prevents the formation of biofilms, accelerating the healing process, effective in anti-inflammatory therapy (patent RF №2156133, BI No. 26, 2000).

The company's funds "Mirra-M" have pronounced biological activity, which is determined by the following components:

- active transport - the microemulsion with a particle size of 0.06 μm and microcapsules with a particle size of 0.02 micron, able to carry into the deeper layers of the skin are diverse in their nature, biologically active substances;

- physiologically useful, absorbed by the skin, the lipid mixture, the components of the micro-emulsions and microcapsules;

- a wide range of biologically active substances (essential oils and vegetable oils, extracts of 60 plants, biotechnology products, seafood and other), balanced picked up and put into cosmetics / products is a mini tool without heat treatment (cold emulsification);

- use of degraded water (without hydroisolation), which greatly increases the efficiency of BAC.

Cosmetics company "Mirra-M not only improve the appearance of skin, improve circulation, reduce inflammation and allergic reactions, reduce painful symptoms, improve the repair and regeneration, reduce swelling, hyperemia and infiltration, ustranyayut dryness etc. Reparative and anti-inflammatory properties balms company "Mirra-M - Merrilyn, Reventon was estimated in 2000 at the Novosibirsk Regional center of allergic and Municipal children's clinical hospital №1 (Feedback on the results of product testing company Mirra-M" № G/87 from 28.02.00, the Ministry of the Russian Federation physical culture, sports and tourism). Anti-inflammatory effect was investigated in the study in the dynamics of the migration of leukocytes in the area of a skin window" (Rebuk modification Mayansky, D.N.). There was observed a decrease of eosinophils in the skin and increase the yield of mononuclear leukocytes, indicating a decrease in the activity of inflammation and stimulation of reparative processes in the skin. On the background of balm content of macrophages in the late phase of cutaneous window was increased from 11.4% to 29.3%, indicating that increased the functional activity of macrophages and stimulation of reparative processes in the skin. to stimulate epithelialization, decreasing the activity of allergic inflammation, relieve skin itch.

Even with the successful result of the operation of post-traumatic phenomena cause the patient's physical and psychological discomfort. Bruising, edema, infiltrates, increased sensitivity of the skin (even if warned in advance), is concerned about the patient. The main task of this stage is rapid tissue repair. Therefore, the early postoperative period should solve the following tasks:

adequate analgesia damaged tissues with a maximum reduction of the dose of analgesics;

- restoration of microcirculation operated or posttraumatic zone, improve the trophic tissue, removal of edema;

- rapid resorption of infiltrates, normalization of permeability of the vascular wall, reducing inflammation;

- activate the regenerative powers of the body, improve metabolism and plastic processes;

- restoration of the immune system at the tissue level and at the level of whole organism.

The choice of means and the sequence of their application depends on the severity of traumatic events and their localization.

Examples of specific implementation method.

In fashion cosmetic rehabilitation of skin tissues in the early and late postoperative the period, for post-traumatic conditions of the skin with the use of company funds "MIRRA-M" using diagrams, which are shown in the examples.

Example 1. Liposuction.

After the surgery, the damaged area is treated with a solution-antiseptic-Furacilinum. 2 through 4 day post-ssanu is applied sequentially from the beginning balm, Merrelyn in an amount of 5 ml 3-4 times daily and massage gently for 5 minutes, then after hematomas from 4 to 10 day put balm Reventon in an amount of 10 ml 2-4 times a day and massage gently for 5 minutes until completely absorbed. 10-15 on days of conducting the same procedures before applying compression underwear.

Example 2. Liposuction.

After the surgery, the damaged area is treated with 0.5% alcoholic chlorhexidine. On 2-3rd day applied alternately first balm "Merrelyn in an amount of 5 ml, and then "Reventon" in the amount of 10 ml per liposuction 2-4 times a day and massage gently until completely absorbed funds. 10-15 on days of conducting the same procedures before applying compression underwear.

Example 3. Surgery is blepharoplasty.

After the surgery the surgical intervention area treated with antiseptic solution Furacilinum. On 2-3rd day on the skin around the eyes put balm "Merrall the n" 3 ml 3-4 times a day with light circular massage movements for 3-5 minutes until completely absorbed, then with a 4-10 day balm Reventon 5 ml, then as hematomas, eliminate swelling cause microemulsion "Eye contour-band" light massage movements on the skin around the eyes in the amount of 0.5 ml

The application continues under the scheme prior to full recovery of the skin of the eyelids.

Example 4. A facelift.

After surgery the area of surgical intervention on the 2-3rd day treated with 0.5% alcoholic chlorhexidine, remove dry crusts, are alternately balms "Merrilyn", "Reventon" in the amount of from 5 ml to the temporal, zygomatic, parotid, perenesennoy, zadnesheynyh area and massage gently for 5 minutes until fully absorbed 2-4 times a day. On day 4-5 same as in 2 and 3 days. Additionally applied the cream mask "Mind" in the amount of from 5 ml.

6-14 day after the removal of the stitches the same as in 2 and 3 days, additionally applied the cream mask "Mind" on the entire face and neck and massage with elements of lymphatic drainage, and when applying the cream-mask "Mind" on the face, neck and décolleté carried out on a cream-mask "Mind" massage, starting from the back of the neck is going to face, neck and décolleté, alternating movements, stroking, rubbing and kneading gently.

Use of proceeds under the scheme prior to full recovery of the skin.

Example fromagerie surgery on the face.

On the 1st-3rd day after surgery in the surgery area causing the Bacteriophage-gel in the form of applications for 10-15 minutes before removing the inflammatory process. The amount is calculated depending on the damaged area from 0.5 to 5 ml For 4-6-iden put balm Reventon in an amount of 5 ml 3-4 times a day for 5 minutes with light massage movements. Then from 7 to 14 days after surgery, clean cotton swabs posttraumatic area cleansing milk in an amount of 5 ml per procedure. After this toning lotion-tonic with a pH of 6.0., maintaining the pH balance of the skin. From 7th to 14th day put cream mask "Mind" in the amount of 5 ml and perform light massage cream mask with elements of lymphatic drainage in a sparing mode. On the cream-mask "Mind" massages, starting from the back of the neck is going to face, neck and décolleté, alternating movements, stroking, rubbing and kneading, and the massage is carried out in a sparing mode.

This procedure is carried out daily until full recovery of the skin.

Example 6.

Surgery on the face.

1-6 day after surgery the area of surgical intervention, and in turn causing the Bacteriophage-gel and balm Reventon. First put a Bacteriophage-a gel in the form of applications for 10-15 minutes in an amount of 1.5 ml, then applied the balm Reventon in the number is TBE 5 ml 2-4 times a day for 5 minutes with light massage movements. Then on the 7th to 14th day after operation clean posttraumatic area cleansing milk in an amount of 5 ml per procedure. After toning lotion-tonic with a pH of 6.0, while maintaining the pH balance of the skin. From 7th to 14th day put cream mask "Mind" in the amount of from 5 ml. After removal of sutures perform light massage cream mask "Mind" on the face, neck and chest massages, starting from the back of the neck is going to face, neck and décolleté, alternating movements, stroking, rubbing and kneading.

Example 7. Trauma to the skin tissue of the face and neck (injury, cuts etc).

On 2-3rd day after treatment of the damaged zone of 0.5% alcoholic chlorhexidine is applied, first balm "Merrelyn in an amount of 5 ml, then 4 on a 10-day put balm "Reventon in an amount of 5 ml and massage gently for 5 minutes until completely absorbed balm 3-4 times a day. Additionally applied the cream mask "Mind" in the amount of from 5 ml.

Just over 3 years according to nosology operated 900 patients, the postoperative rehabilitation program using cosmetics Mirra-Lux passed 710 people (main group), the remaining 190 patients for one reason or another did not use this cosmetics in the postoperative period, the control group. The table presents the results of rehabilitation care is OGA in the early postoperative period.

Evaluation of the effectiveness of the proposed method was carried out at the Department of plastic and reconstructive surgery of the Chelyabinsk regional hospital No. 1.

The results of the rehabilitation period was estimated by reducing the inflammatory response and local fabrics, General body condition: extent, reduce swelling, reduce redness, bruising, less pain. Excellent believed to result when the improvement in all of the above symptoms occurred on 3-4 day good - if improvement occurred 2-3 signs or 5-6 days.

In almost all cases, the patients completed a rehabilitation program with the use of cosmetics companies Mirra-M, was a decrease swelling, pain, bruising on 3-4 day that was regarded as an excellent result. The negative impact of the means was not observed. In the control group the reduction of swelling and pain were observed in a period of 5 days or more. The results are shown in the table.

The proposed method cosmetic rehabilitation of the fabrics can be used in plastic surgery, reconstructive microsurgery in early and late postoperative periods in patients for management of patients with different types of operations (facelift, blepharoplasty, liposuction and other), in the rehabilitation of tissues in post-traumatic phenomena, promettere, when the sex-change surgeries, etc. using medical cosmetics company "Mirra-M".

The results of the evaluation with the cosmetic rehabilitation of the fabrics in the postoperative period and other post-traumatic conditions.

OperationThe group of patientsOccupancyResults
exgood
Liposuction of the face, neckThe main group1921902
The control group41041
Liposuction bodyThe main group1641613
The control group42042
BlepharoplastyThe main group1211201
The control group38137
FaceliftThe main group1241213
The control group34034
Blepharoplasty + faceliftThe main group1191172
The control group35035
InjuryThe main group1275
The control group514

1. The way cosmetic rehabilitation of the skin tissue in the postoperative period and other post-traumatic conditions, including the use of medical-cosmetic products, characterized in that after damage to cleanse, treat the damaged area antiseptic and applied sequentially or alternately balms, Merrilyn and Reventon, while the sequential application of balms from 2 to 4 day applied the balm Merrilyn with analgeziruushim, anti-inflammatory and absorbing effects, 3-4 times a day and massage gently for 5 min, and as hematomas from 4 to 10 day put balm Reventon with vessel restorative action to help reduce the swelling and improvement of microcirculation, 2-4 times a day and massage gently for 5 minutes until completely absorbed, and in the case of processing alternate use is for first applied the balm Merrelyn, then balsam Reventon the above methods, and in accordance with the nature of the traumatic condition for fabric blefaroplastia addition put microemulsion "Eye contour-band"with restorative, revitalizing effect on the skin of the eyelids, light massage in a circular motion, and when the facelift is additionally applied the cream-mask "Mind"with bactericidal, vessel restorative, regenerating effect.

2. The method according to claim 1, characterized in that when the facelift in addition to treatment cream mask "Mind" on the face, neck and décolleté after removal of sutures spend massage in gently, starting from the back of the neck, passing over face, neck and décolleté, alternating movements, stroking, rubbing and kneading.

3. The way cosmetic rehabilitation of the skin tissue in the postoperative period and other post-traumatic conditions, including the use of medical-cosmetic products, characterized in that after damage to cleanse the skin and is applied sequentially or alternately Bacteriophage-gel and balm Reventon, if consistent application of funds 1 through 6 day put Bacteriophages, which disinfects the surface of the skin, prevents the formation of biofilms, thereby accelerating the healing process, for 10-15 minutes until the disappearance of bruises, oteco and removal of the inflammatory process, then balsam Reventon with vessel restorative action to help reduce swelling and improves microcirculation, 2-4 times a day for 5 min. until completely absorbed light massage movements, and in the case of processing alternate use, first put the Bacteriophage-gel, then balm Reventon the above methods, and in accordance with the nature of the traumatic condition in surgery on the face 7 to 14 day cleanse posttraumatic area milk cleanser, then tone up lotion-tonic, and then apply the cream-mask "Mind"with bactericidal, vessel restorative, regenerating effect.

4. The method according to claim 4, characterized in that during surgery on the face in addition to treatment cream mask "Mind" on the face, neck and chest massages, starting from the back of the neck, passing over face, neck and décolleté, alternating movements, stroking, rubbing and kneading, and the massage is carried out after the removal of the stitches in a sparing mode.



 

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6 ex

FIELD: medicine, contraception.

SUBSTANCE: invention proposes antibacterial and contraceptive compositions that comprise the following components: (1) matrix-forming substance; (2) bioadhesive substance; (3) buffer substance; (4) moistening substance, optionally; (5) preserving agent, optionally, and (6) water. Proposed compositions are suitable for their placement into vagina wherein compositions form semisolid matrix in contact with testicular fluid, cause thickening cervical mucus, form a bioadhesive layer on vagina surfaces, maintain the natural acid pH value in vagina about less 5 in the presence of testicular fluid ejected by a male and don't disturb essentially the natural microbiological balance in vagina. Compositions and methods decrease and/or prevent transfer of diseases transferring by sexual way and act as vaginal contraceptives with less adverse effect as compared with conventional vaginal contraceptives and can be used therefore for a long time. Compositions and methods are simple for using and don't require a physical device for their retention into vagina during using.

EFFECT: improved and valuable properties of compositions and methods.

36 cl, 17 tbl, 11 ex

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to an agent for topical using used in treatment of joint diseases. The proposed agent comprises glucosamine salt, chondroitin sulfate and dimethylsulfoxide incorporated into an acceptable ointment base. Invention provides enhancing effectiveness due to using low-molecular saccharides that results to elevating diffusion delivery rate of the substance to the joint zone and providing the achievement of synergistic effect in treatment of joint diseases.

EFFECT: enhanced effectiveness and valuable medicinal properties of agent.

2 cl, 3 ex

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to preparations for external using in treatment of joint diseases. The proposed agent comprises a saccharide - glucosamine salt and dimethylsulfoxide incorporated into an acceptable ointment base. Invention provides enhancing effectiveness of agent due to using low-molecular saccharides that results to the elevating diffusion delivery rate of active substance to the join zone.

EFFECT: improved and valuable properties of agent.

2 cl, 5 ex

FIELD: medicine, dermatology, pharmacy.

SUBSTANCE: invention relates to a pharmaceutical gel composition for applying on skin. The composition comprises at least one vitamin D or analog of vitamin D, at least one corticosteroid, at least one solvent and an excipient enhancing viscosity. Viscosity value of the composition is in the range from 5 mPa x s to 500 mPa x s. The composition is designated for treatment of psoriasis and associated states in humans. The composition is suitable for applying on skin, shows the improved absorption and stable at 40°C in storage for 3 months.

EFFECT: improved and valuable properties of composition.

22 cl, 2 tbl, 1 ex

FIELD: medicine, endocrinology, pharmaceutical technology, pharmacy.

SUBSTANCE: invention relates to nateglynide-containing preparation used in treatment of diabetes mellitus that comprises nateglynide as an active component and a carrier wherein nateglynide in amorphous form and indicated carrier represents hydrophilic material. Amorphous property of crystalline nateglynide is provided by the following methods: 1) by dissolving nateglynide crystals in pharmacologically acceptable solvent in common with hydrophilic materials taken among the group consisting of water-soluble polymers, water-swelling polymers, sugar alcohols and salts followed by granulation in fluidized layer, granulation by stirring at high rate, drying by spraying and process for coat applying for granulation of amorphous nateglynide; 2) by mixing nateglynide crystals with hydrophilic materials taken among the group of water-soluble polymers, water-swelling polymers, sugar alcohols and salts and the following application of the high shift force to the prepared mixture; 3) by mixing nateglynide crystals with hydrophilic materials taken among the group of water-soluble polymers, water-swelling polymers, sugar alcohols and salts and the following plasticizing the prepared mixture in melt by heating and milling at cooling; 4) by dissolving nateglynide crystals in pharmacologically acceptable liquid additives wherein liquid additives represent water-soluble polymers that are liquid at 37°C. Using amorphous nateglynide allows preparing the nateglynide preparation with immediate release wherein the dissolving rate of medicinal agents is high and without crystalline transition during preparing or preserving preparations.

EFFECT: valuable pharmaceutical properties of preparation.

6 cl, 3 tbl, 9 dwg

FIELD: medicine, pharmacy.

SUBSTANCE: invention proposes using xenogenous oligo-and/or polyribonucleotides, namely total RNA and tRNA, as an active component of external anhydrous medicinal agent for a single treatment of skin tumor relapse (for example, basalioma) or infections caused by herpes virus and the corresponding method for treatment. The claimed external anhydrous medicinal agents decline effectively relapses of indicated diseases after a single intake.

EFFECT: enhanced effectiveness and valuable medicinal properties of agents.

5 cl, 2 ex

FIELD: veterinary science.

SUBSTANCE: the suggested preparation contains dense propolis, vegetable oil, extract out of dead bees based upon glycerol, lanolin, honeycombs' cutting off, moreover, all the components should be taken at certain quantitative ratio, weight%: honeycombs' cutting off 15-20, dense propolis 20-25, extract out of dead bees upon glycerol 7.5 -10, lanolin 20-25, vegetable oil - the rest, moreover, honeycombs' cutting off includes honey residues. The preparation in question is of high biological activity, provides shortened terms for recovery in animals and excludes allergic reactions.

EFFECT: higher efficiency for therapy.

1 cl, 8 ex

FIELD: medicine, phytotherapy, infectious diseases, pharmaceutical industry.

SUBSTANCE: invention relates to a method for preparing ointment used in erysipelas treatment. Method for preparing ointment used in erysipelas treatment involves milling washed and dried viper's-bugloss roots (Echium rubrum, Jacg, family Boraginaceae) and their extraction with melted butter under the definite conditions. Then extract is infused at stirring for a definite time, macerate is filtered off at cooling to a definite temperature and poured off. Extraction is carried out twice, vegetable raw residues are squeezed out, and prepared sap is combined with first two extracts, settled for a definite time and bottled. Method provides preparing ointment that promotes to effective treatment of erysipelas and reducing treatment period.

EFFECT: improved preparing method, valuable medicinal properties of ointment.

5 ex

FIELD: medicine, urology.

SUBSTANCE: the present innovation deals with means for external application. The suggested gel-like preparation contains hydroxyethylcellulose polymer as a gel foundation, lidocaine hydrochloride, an antiseptic component - benzalconium chloride (50%), gentamycin and water. The remedy is nontoxic and easy in application, it demonstrates no unfavorable side irritating action being of high penetrating capacity of active components.

EFFECT: higher efficiency of application.

1 cl, 1 dwg, 7 ex

FIELD: cosmetology, in particular cosmetic and/or dermatological agents.

SUBSTANCE: claimed emulsion contains perfluorocarbons, water, oil phase and emulsifier. Additionally oil phase contains essential oil as agent for increased oxygen utilization by skin. Emulsion of present invention allows skin saturation with oxygen and expedites oxygen utilization interruption by skin.

EFFECT: emulsion increasing oxygen utilization rate in all epidermis layers.

4 cl, 1 ex, 1 tbl, 3 dwg

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