Method for obtaining sodium selenite solution based upon corn germs oil

FIELD: veterinary.

SUBSTANCE: one should preliminarily dissolve 0.1 g sodium selenite dried up to constant weight in glycerol at phase ratio being 1:10 at heating at water bath at 60° C, or at phase ratio being 1:20 at 20° C at mixing, then the obtained solution should be supplemented with 100 g corn germs oil at constant mixing to obtain homogeneous solution. The innovation could be applied to obtain preparation for regulating metabolic processes in animal bodies. The method provides remedy containing natural biologically active complexes to enhance its antioxidant action.

EFFECT: higher efficiency.

 

The invention relates to veterinary pharmacy and can be used to obtain the regulating metabolic processes and complementary deficiency of vitamin E and selenium in animals. Selenium is an essential trace element for animals and the importance of physiological values equivalent to vitamin E (Microelementoses person / Apelcin, Have, Mais, Lostracco. - M.: Medicine. 1991. - S-231).

A known solution of sodium Selenite, prepared by dissolving sodium Selenite in water. These solutions are colorless, transparent, but unstable. They are suitable for 3-5 days (Ivithin. Feeds and feed additives. Handbook, Moscow, Rosagropromizdat, 1989, S).

In veterinary medicine used as drug Neosulin. Neosulin is 0.1% and 0.5% solutions of sodium Selenite in 8% ethanol. In appearance it is a colorless transparent liquid. The disadvantage is the use as solvent of ethyl alcohol. (Guidance on the application of Dioselina for animals approved by the veterinary Department of the Ministry of agriculture and food of the Russian Federation. Registration number HBP-2-3.0/00388).

Adopted as a prototype drug Celery (vitamin E with sodium Selenite for injection). It is a combination drug which is a liquid yellow-green is the main color with a slight opalescence. As solvent selected oil solution of vitamin E, which in our opinion is a disadvantage, because synthetically derived vitamin E significantly inferior to their antioxidant properties, natural tocopherol (Guidance on the application of Celerra (vitamin E with Selenite sodium for injection) in veterinary medicine, approved by the veterinary Department of the Ministry of agriculture and food of the Russian Federation. Registration number PTS-2-2.0/00408).

The disadvantage of the prototype in our opinion is the fact that the product contains tocopherol acetate, which is a synthetic analogue of vitamin E activity compared with natural much lower.

The aim of the invention is the creation of a combined Supplement of sodium Selenite and biologically active complex representing corn germ oil, containing up to 200 mg % of vitamin E.

The main feature of the proposed new comprehensive multivitamin preparation is that the drug Semanur And cook in butter corn germ, which in itself is a natural concentrate of biologically active substances: Tocopherols up to 200 mg %, of which 90% are γ-tocopherol, a natural antioxidant, carotenoids 0,90-0,155 mg %, polyunsaturated fatty acids, Pitot is Renov - 0,42-1,38 mg %, which improves the stability, effectiveness and efficiency (reduces its cost by 20%) of the proposed drug (Semeradova A.B. Pharmaco-chemical study of oil from corn germ / Abimelech. Pyatigorsk, 2002. - 26 S. - Dept. in VINITI 09.08.2002, No. 1466-In-2002).

The drug is produced as follows:

0.1 g sodium Selenite, dried to constant weight, dissolved in glycerol at a ratio of phases 1:10 when heated on a water bath at a temperature of 60°or when the ratio of phases 1:20 at a temperature of 20°C, under stirring and then the resulting solution was added with constant stirring 100 g of corn germ oil until a homogeneous solution. The resulting product has a weak light.

The advantage of the proposed method is that as a carrier for sodium Selenite use oil, corn germ, the uniqueness of which is due to the presence of biologically active complexes: antioxidants (Tocopherols - 170-200 mg %, carotenoids 0,09-0,155 mg %), polyunsaturated fatty acids, phytosterols - 0,42-1,38 mg %, vitamin K. the Presence in the preparation of biologically active natural complexes enhances the antioxidant effect of the drug, inhibiting lipid peroxidation and accumulation of products of the peroxide okelani is in organs and tissues, including in plasma.

The method of obtaining oil solution of sodium Selenite, characterized in that dried to constant weight 0.1 g sodium Selenite is dissolved in glycerol at a ratio of phases 1:10 when heated on a water bath at a temperature of 60°or when the ratio of phases 1:20 at a temperature of 20°with stirring, and then to poluchenogo solution was added under stirring with 100 g of corn germ oil until a homogeneous solution.



 

Same patents:

FIELD: medicine, in particular agent for hand cleaning without water application.

SUBSTANCE: claimed agent contains polyvinyl alcohol bearing 8-13 of acetate groups and having dynamic viscosity from 23 to 47 Pa.c.103, or mixture of polyvinyl alcohol bearing 0.8-2.0 of acetate groups and having dynamic viscosity from 17 to 25 Pa.c.103 with polyvinyl alcohol bearing 8-13 of acetate groups and having dynamic viscosity from 16 to 19 Pa.c.103 in ratio of 1:(0.4-1.5), ethanol and water. Additionally agent contains PEG-40 and hydrogenised castor oil in specific ratio (mass %).

EFFECT: agent for hand cleaning applicable at minus temperatures without losses of consumption properties.

8 cl, 2 ex

FIELD: antiperspirant deodorant products.

SUBSTANCE: claimed product contains salt with antiperspirant activity and water soluble polymer, containing Bronsted acids, which acts as co-thickener when blending with antiperspirant salt in presence of water. Before application polymer is physically divided from antiperspirant salt.

EFFECT: antiperspirant product of improved effectiveness.

21 cl, 7 ex, 7 tbl

FIELD: cosmetology, in particular skin care products.

SUBSTANCE: claimed agent contains bioactive components, namely albumin, placenta hydrolyzate, and sodium alginate. Additionally it may contain target additives, glycerol and essential oils. All components are used in specific qualitative ratio.

EFFECT: cosmetic product of antimicrobial, moistening, stimulating, antiallergic, and sorption action, capable of stimulation repairer and smoothing processes.

2 cl, 8 ex

FIELD: cosmetology, in particular skin care products.

SUBSTANCE: claimed agent contains bioactive components, namely albumin, placenta hydrolyzate, and sodium alginate. Additionally it may contain target additives, glycerol and essential oils. All components are used in specific qualitative ratio.

EFFECT: cosmetic product of antimicrobial, moistening, stimulating, antiallergic, and sorption action, capable of stimulation repairer and smoothing processes.

2 cl, 8 ex

FIELD: cosmetic industry, in particular cosmetic agent for skin protection.

SUBSTANCE: claimed agent contains vitamin A compound and/or derivatives thereof, quinothiol, epidermal lipid and/or analog thereof selected from group containing sterols and/or derivatives thereof, sphingolipids and/or derivatives thereof, phospholipids and/or derivatives thereof, and glycerides and/or derivatives thereof, as well as desired additive. All components are used in specific ratio.

EFFECT: agent to improve dry skin state, to prevent corrugation formation and similar defects caused by losses of skin elasticity and resiliency.

2 cl, 6 ex, 5 tbl

FIELD: cosmetic industry, in particular cosmetic agent for skin protection.

SUBSTANCE: claimed agent contains vitamin A compound and/or derivatives thereof, quinothiol, epidermal lipid and/or analog thereof selected from group containing sterols and/or derivatives thereof, sphingolipids and/or derivatives thereof, phospholipids and/or derivatives thereof, and glycerides and/or derivatives thereof, as well as desired additive. All components are used in specific ratio.

EFFECT: agent to improve dry skin state, to prevent corrugation formation and similar defects caused by losses of skin elasticity and resiliency.

2 cl, 6 ex, 5 tbl

FIELD: agents for skin care, injury repair, and skin protection from harmful environment factors and pathogenic organisms.

SUBSTANCE: claimed agent contains polyethylene glycol of high polymerization degree n = 32-800, glycerol, lanthanum nitrate, sodium hydroxide, and water, and additionally it contains Panavir (new Russian antiviral drug), polyethylene glycol of polymerization degree n = 4-8. All components are used in specific quantitative ratio.

EFFECT: agent of improved properties, namely homogeneity and rheological properties, and increased applicability.

2 cl, 2 ex, 1 tbl

FIELD: medicine, dermatology, pharmaceutical industry, phytotherapy.

SUBSTANCE: invention relates to using extracts from Serenoa repens and Vitis vinifera for preparing oral compositions used in treatment and prophylaxis of alopecia, dandruff and seborrhea. Oral compositions prepared of extracts of Serenoa repens and Vitis vinifera promote to the effective treatment and prophylaxis of alopecia, dandruff and seborrhea. Invention is used in treatment and prophylaxis of alopecia, dandruff and seborrhea.

EFFECT: valuable medicinal properties of compositions.

4 tbl, 2 ex

FIELD: medicine, dermatology, pharmaceutical industry, phytotherapy.

SUBSTANCE: invention relates to using extracts from Serenoa repens and Vitis vinifera for preparing oral compositions used in treatment and prophylaxis of alopecia, dandruff and seborrhea. Oral compositions prepared of extracts of Serenoa repens and Vitis vinifera promote to the effective treatment and prophylaxis of alopecia, dandruff and seborrhea. Invention is used in treatment and prophylaxis of alopecia, dandruff and seborrhea.

EFFECT: valuable medicinal properties of compositions.

4 tbl, 2 ex

FIELD: medicine, phytotherapy, pharmacy.

SUBSTANCE: invention relates to the development of medicinal agents of vegetable origin. The medicinal preparation possessing with rejuvenating effect on human body comprises a mixture of dry extracts prepared of grape peel of dark strains, olive tree leaves, rosemary leaves, grape seeds, and also gum arabic and aerosil. The preparation enhances resistance of body against unfavorable environment factors, decelerates ageing processes and stimulates recovery processes of body. Invention can be used for increase of body cells span-life and showing the rejuvenating effect on the human body.

EFFECT: valuable medicinal properties of preparation.

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to a pharmaceutical composition used for stabilization of homeostasis and arresting pathological processes in the body. Invention proposes a pharmaceutical composition as powder with particles size from 250 to 400 mcm comprising the following components by the first variant, wt.-%: carbon, 10.01-53.02; oxygen, 30.10-53.10; potassium, 0.26-1.99, and calcium, 0.20-31.37, and comprising the following components by the second variant, wt.-%: calcium, 0.35-31.20; carbon, 10.99-50.21; oxygen, 34.55-51.03; sulfur, 0.73-14.81, and phosphorus, 0.08-3.30. Invention provides compensation of trace elements unbalance that causes and accompanies many diseases, possibility for stabilization of trace element homeostasis and arresting pathological processes of different etiology.

EFFECT: improved and valuable medicinal properties of composition.

12 cl, 13 ex

FIELD: veterinary science.

SUBSTANCE: the present innovation deals with supplementing the feedstuff with mineral additive as neutralized white slime of alumina production of the following composition, weight%: aluminum oxide 25-35; silicon oxide 20-25; iron oxide 3-10; calcium oxide 3-10; sodium oxide 15-20; sulfur oxide 3-6; potassium oxide 0.5-2.0, free alkali, 0.02, not more; weight portion of moisture 15, not more, to be introduced once daily for about 5-7 d before transportation at the dosage of 200-300 g/animal/d. The innovation provides decreased level of stress and loses of meat productivity in cattle.

EFFECT: higher efficiency.

4 tbl

FIELD: veterinary science.

SUBSTANCE: the present innovation deals with applying a multi-purpose complex preparation that contains the following components in 1 l of distilled water: sodium selenite 1.0; vitamin E/in the form of combinal E/7500 mg; succinic acid 10.0; zinc sulfate 10.0 and pharmazine 50000 U. The preparation should be introduced as intramuscular injections 45, 30, 15 d before delivery and during the day of delivery: in cows per 10-15 ml, for pigs and sheep per 5 ml, for youngsters after the birth: in calves - 5 ml, in piglets and lambs per 1-2 ml, in hens per 0.5 ml once/2 wk. The innovation is very efficient in increasing the quality and quantity of production, improving the growth and development in fetus and offspring, preventing some surgical and obstetric-gynecological pathologies.

EFFECT: higher efficiency of correction.

5 cl

FIELD: veterinary medicine, pharmacy.

SUBSTANCE: invention proposes ointment comprising tartaric acid, precipitated sulfur, boric acid, wax, colophony and vegetable oil taken in the definite ratios. The ointment provides healing damaged tissue of animal being without adverse effect.

EFFECT: valuable curative properties of ointment.

1 tbl

FIELD: veterinary science.

SUBSTANCE: one should introduce dimethylpyrazolyl selenide for dry cows at the dosage of 10 mcg/kg on the 25-30th and 15-18th d before calving. The present innovation enables to activate cellular and humeral immunity and increase reproductive function in dry cows that, in its turn, favours more intensive growth and development in youngsters.

EFFECT: increased performance in youngsters.

2 dwg, 4 ex, 5 tbl

FIELD: applied immunology.

SUBSTANCE: composition contains, wt parts: borax decahydrate1-25, sodium thiosulfate pentahydrate 10-5-10-4, potassium carbonate 30-150, refined sugar 30-200, and water 100-200 per 100 wt parts of sodium metasilicate pentahydrate. In addition to its capability of improving resistance to diseases, body weight increase, productivity of agricultural plants, quality of crop, and ripening term (harvest time), composition according to invention possesses nonspecific immunostimulating activity, including production of antibodies and enhancement of immunity through activation of immunocytes thereby maximally strengthening vaccination effect regarding diseases caused by malignant neoplasm viruses.

EFFECT: increased assortment of immunostimulating agents.

10 cl, 11 dwg, 12 ex

FIELD: medicine, endocrinology.

SUBSTANCE: at the background of applying microdosages of iodine and/or levothyroxine one should conduct electrophoresis with 3%-sodium thiosulfate solution. The latter should be introduced with the help of a cathode placed onto thyroid area, an anode - onto interscapular area. The area of the interlayer corresponds to 5 x 10 cm at current power being 4-8 mA, exposure time being 15-20 min. Seances should be performed either daily or every other day, about 10-12 procedures/course.

EFFECT: higher efficiency of therapy.

3 ex

FIELD: poultry science.

SUBSTANCE: one should daily introduce sodium selenite into chickens' diet at the quantity of 1.5 mg selenium/kg feedstuff. The method enables to decrease the content of lead in muscular tissue by 69.8-78.4%, in bones - by 74.4%.

EFFECT: higher efficiency of lead withdrawal.

2 tbl

FIELD: veterinary science.

SUBSTANCE: about 20-25 d before calving one should introduce intramuscularly 0.5%-sodium selenite solution for cows at the dosage of 10 ml. Twice before and twice after calving at 10-d-long interval - tetravit at the dosage of 10 ml at the content of 50000 IU vitamin A, 25000 IU vitamin D, 20 mg vitamin E and 5 mg vitamin F per 1 ml. Succinic acid should be introduced 20-25 d both before and after calving at the dosage of 1.0 g. The method provides efficient correction of the main values of homeostasis in cows after calving.

EFFECT: higher efficiency of normalization.

2 ex, 4 tbl

FIELD: veterinary pharmaceutics.

SUBSTANCE: the present innovation deals with a complex oily polyvitaminic preparation that regulates metabolic processes and decreases the frequency of selenium deficiency manifestation in animal body, poultry, among them, and contains selenium in the form of sodium selenite, retinol acetate as vitamin A and oily solvent in the form of corn germs oil. Thus, cheaper, more active and more stable complex preparation has been obtained that regulates metabolic processes and decreases the frequency of selenium deficiency manifestation in animal and poultry bodies.

EFFECT: higher efficiency of application.

1 ex

FIELD: medicine.

SUBSTANCE: the present innovation includes synthetic zeolite Na-A, sulfur and flavoring at the following ratio of components, weight%: sulfur 0.03-0.08, flavoring 1.0-1.5, synthetic zeolite Na-A - the rest. As flavoring one should apply food flavorings with the odor of vanillin, lemon, prune, almond, coffee. Organoleptic evaluation of preparation's properties has shown that it causes no irritation of human hand skin: hands become dry and demonstrate pleasant odor. Due to supplementing sulfur the suggested preparation provides elimination of harmful microflora, protects hand skin against infection. Preparation is simple to be manufactured and applied along with its low price and ecological safety.

EFFECT: higher efficiency.

1 cl, 1 tbl

Up!