Electrocardiographic signal registration device

FIELD: medicine; cardiology.

SUBSTANCE: device can be used in clinical and experimental tests for registration; analysis and transmission of electrocardiographic signal. Parameters of electrocardiographic signal are determined at any point of patient's body due to finding projection of vector of electrocardiographic signal of heart at any preset direction. Device has amplifier, analog-to-digital converter with multiplexer, arithmetic unit, increment code analyzer, switch unit, digital modem, increment code number counter, memory and control units, unit for forming projections of vector of electrocardiographic signal of heart and unit for finding value of vector of electrocardiographic signal of heart at preset direction.

EFFECT: widened operational capabilities.

3 cl, 5 dwg

 

The present invention relates to medicine, can be used for registration, analysis and transmission of electrocardiogram (EX).

Classical methods of recording and analysing the FORMER have already exhausted their resources, and therefore are searching for improving diagnostic capabilities using new methods of processing and analysis of the FORMER.

In any textbook of cardiology or on the Internet site dedicated to cardiology, the methods of diagnosis of diseases of the cardiovascular system according to EX 12 standard leads. The disadvantages of the known methods include manual (non-automatic) analysis and definition of the information parameters EX, as well as the inability to more fully understand the picture of the spatial distribution of the FORMER on the body surface of the patient.

One method that addresses the shortcomings of the analysis techniques of the FORMER standard, conventional leads, is the outer EX-mapping. The essence of this method consists in increasing the number of electrodes that register with EX chest, which automatically leads to an increase in information about the electrical activity of the heart and allows more complete picture of the distribution of potentials observed on the body surface.

A device for transmitting EX [1], containing sequentially connect the main amplifier, the multiplexer and the analog-to-digital Converter, an arithmetic device, a buffer memory, a digital modem that implements the transfer method with the storage of the incoming data and transfer it in offline mode with a speed corresponding to the characteristics of the communication channel.

The disadvantages of the known device is that you want a great time employment communication channel for transmission of information and a large buffer memory device for remembering at the transmitting end and the subsequent transfer of large amounts of information from the Desk of the FORMER from the set of derivations (the number of points can vary from 100 to 400).

Known selected as a prototype of the device for recording the FORMER [2], containing connected in series amplifier, analog-to-digital Converter with multiplexer and the arithmetic unit, and the code analyzer increments, a switch unit, a digital modem, the counter non-code increment the memory unit and the control unit, and the analyzer input codes increment is connected to the output of the arithmetic unit, the first output of the analyzer code increment connected to the first input switch unit, the second to the first input of the memory block, and a control output to the first input of the counter code number increment, the second input of which is connected on with the first output control unit, the second and third outputs of the latter are connected respectively with the control input of the switch unit and the second input of the analog-to-digital Converter, and the output number counter code increment connected with the second input of the memory block, the output of which is connected with the second input of the switch unit, and the output switch unit with modem input.

To the disadvantage of the known device is the fact that it has no more complete than in 12 standard leads, views picture of the spatial distribution of the FORMER on the body surface of the patient.

In the known device registered EX is only represented by a set of code samples in the time domain in 12 standard leads. As noted above, from the point of view of the representation of diagnostic information is not enough. Therefore, to achieve with EX in the standard derivations of the amount of diagnostic information obtained by the method of EX-mapping, using methods of mathematical processing of the FORMER in standard leads.

It is obvious that the registration of the ECG signal is not an end in cardiology. The process of cardiac information, in addition to registration, includes the steps of analysis and diagnosis. The ECG signal is primary is the LEM diagnostic information, and fixing at check out as much as possible this information will provide more opportunities for analysis and will significantly improve the accuracy of diagnosis. Analysis of the electrocardiographic information is essential when planning a course of treatment, decision making in the diagnosis, finding ways to increase the effectiveness of treatment.

According to the authors of the present invention, it is necessary for the registration of the ECG signal to expand the scope of representation of diagnostic information by defining parameters EX, not only in standard leads, but also to use the received data to determine parameters EX at any point on the body surface of the patient by finding the projection of the vector EMF heart in any given direction. The FORMER mapping is an expensive method of diagnostics of the cardiovascular system and is used in clinical studies. Therefore, the achievement of the functional capabilities of the EX-mapping using standard ECG method would, in the opinion of the authors, to improve the efficiency of diagnostics of the cardiovascular system during preventive examinations.

The invention is directed to expand the functionality of electrocardiographic studies by determining the projection of the DS of the heart in a given direction.

This is achieved by the fact that in the device for recording of electrocardiogram containing connected in series amplifier, analog-to-digital Converter with multiplexer and the arithmetic unit, and the code analyzer increments, a switch unit, a digital modem, the counter non-code increment the memory unit and the control unit, and the analyzer input codes increment is connected to the output of the arithmetic unit, the first output of the analyzer code increment connected to the first input switch unit, the second to the first input of the memory block, and a control output to the first input of the counter code number increment, a second input connected to the first output block management, second and third outputs of the latter are connected respectively with the control input of the switch unit and the second input of the analog-to-digital Converter, and the output number counter code increment connected with the second input of the memory block, the output of which is connected with the second input of the switch unit, and the output switch unit with modem input entered connected in series forming unit projection vector EMF heart and the power determination value vector EMF of the heart in a given direction, while the first and second inputs of the processing unit projection vector EMF hearts are connected to appropriate what about the third output of the control unit and the output of the analog-to -digital Converter, the fourth output control unit connected with the second input of the block defining the value of the vector EMF of the heart in a given direction, the output of which is connected to the third input of the switch block, the block forming projections of the vector EMF heart contains a second memory block, and connected in series respectively to the first multiplier with the first accumulating the adder, the second multiplier with the second accumulating the adder, the third multiplier with the third storing the adder, the first inputs of the multipliers and the input of the second memory block is connected to the third output of the control unit, second and third inputs of multipliers connected respectively with the output of the analog-to-digital Converter and the output of the second memory block the outputs of the adders are output processing unit projection vector EMF heart, the block defining the value of the vector EMF of the heart in a given direction contains the fourth, fifth, sixth, seventh, eighth, ninth, tenth, eleventh and twelfth blocks the multiplication first, second, third and fourth adders, the block extracting the root and the third memory block, the third memory block is connected to the fourth output control unit, and the first inputs of the fourth, fifth, sixth, seventh, eighth and ninth multiplier units are connected respectively with the passages of the first, the second and third accumulative adders block the formation of the projections of the vector EMF heart, the second inputs of the fourth, fifth, sixth, seventh, eighth and ninth multiplier units connected to the output of the third memory block, the outputs of the fourth and fifth multiplier units are connected respectively with the first and second inputs of the first adder, the outputs of the sixth and seventh multiplier units are connected respectively with the first and second inputs of the second adder, the outputs of the eighth and ninth multiplier units are connected respectively with the first and second inputs of the third adder, the first and second inputs of the tenth block multiplication combined and connected to the output of the first adder, the first and second inputs eleventh block multiplication combined and connected to the output of the second adder, the first and second inputs of the twelfth unit of the multiplication of the joint and is connected to the output of the third adder, the first, second and third inputs of the fourth adder connected respectively to the outputs of the tenth, eleventh and twelfth multiplier units, sequentially connected to the operation block root extraction, the output of which is the output of the block defining the value of the vector EMF of the heart in a given direction.

Put the blocks and their relationships are new properties that allow you to increase upon registration of the volume of the diagnostic information by determining the projection of the vector EMF of the heart in a given direction.

The figure 1 shows an image of the heart and vector EMF hearts in three-dimensional space with the designation of the coordinate axes and coordinate planes and angles αxthat αythat αz.

The figure 2 shows a representation of the standard abduction in the frontal plane and the horizontal plane and the representation of the spatial coordinate system of the person in the form of a cylinder is an ellipse.

The figure 3 shows the structural diagram of the device for registration of electrocardiogram.

The figure 4 shows the structural block circuit diagram of the formation of the projections of the vector EMF heart device to register electrocardiogram.

The figure 5 shows the structural block circuit diagram of the determination value vector EMF of the heart in a given direction device for registration of electrocardiogram.

The essence of the invention consists in the following. By registered in 12 standard leads FORMER are determined by the values of the projections of the vector EMF of the heart in the frontal, horizontal and sagittal planes. Then in a given direction is determined by the value of the vector EMF heart with regard to the view model of the human body. The heart is a three-dimensional body and, obviously, its electrical activity should be presented in the space, Breakfast is as. During contraction of the heart muscle is simultaneous excitation of many areas of infarction, and the direction vector of depolarization and repolarization in each of these areas can be different and even opposite. While the ECG records some total or resultant EMF heart at the moment of excitation. The vector resultant EMF heart moves in the chest in three-dimensional space in the frontal, horizontal and sagittal planes. Determining the projection of the vector EMF in a given direction gives the opportunity to find the potential distribution on the surface of the human body, which, in turn, significantly increases the accuracy of the solution of the inverse problem of electrocardiography (finding the configuration of the equivalent generator electrical activity of the heart on the parameters of the resulting field on the body surface).

The direction of the vector EMF hearts in three-dimensional space (see figure 1) is directing cosines of the angles αxthat αythat αz. The direction of projection vector EMF of the heart in the frontal, horizontal and sagittal planes defined by the Euler angles α, β, γ [3].

Standard leads from limb, you can analyze the projection of the vector of the heart in the frontal plane (Hugo the α ), and in chest leads - on the horizontal plane (angle β) (see figure 2). For the calculation of the potentials on the body surface are two interrelated coordinate system relative to the characteristic anatomical landmarks on the body surface, is Cartesian and cylindrical. The beginning of a Cartesian coordinate system XYZ is approximately in the center of the middle transversal cross-section of the chest. The average transversal cross-section is a cross section of a body placed in a vertical position, the horizontal plane (XY plane HOU)passing through the geometric center of the heart ventricles. External anatomical landmark to define this plane is the point between the 4th and 5th intercostal space at the sternal border. More accurately its position in relation to the heart can be detected by radiography. Average sagittal cross-section is a cross section of the body vertical plane of its symmetry (XY plane yOz) and middle frontal cross-section is a cross section of the body vertical plane perpendicular to the above-mentioned two planes (coordinate plane xOz). Main plane of the cylindrical coordinate system rψz coincides with the XY plane HOU Cartesian z-axis of the cylindrical system coincides with the z axis of the Cartesian system, and the angular CCW is dinata ψ measured from the direction of the x axis towards the y-axis of the Cartesian system.

The direction of the EMF of the heart in a single fixed point in time represents the torque of the electric axis of the heart. The direction of this axis during ventricular depolarization changes all the time and also is an important diagnostic parameter characterizing the state of the cardiovascular system at a given time. If we project this vector on a straight line connecting the center of the heart with the point on the surface of the body, and to take into consideration the heterogeneity of the conducting medium, it is possible to obtain the potential generated by the heart on the body surface (see figure 2). Repeating this procedure for different surface points, we obtain the potential distribution on the body surface. This distribution is extremely important in the simulation of the equivalent generator electrical activity of the heart, as it allows to significantly improve the accuracy of calculations.

In the proposed device for standard leads from the limb is determined by the vector projection of the heart in the frontal plane, and in chest leads - on the horizontal plane. Then the projections of the vector heart on the front and the horizontal plane is determined by the projection of the vector heart on the sagittal plane. Next (see figure 2) sets the direction of the pressure in the cylindrical system of coordinates (angles α that β, γ)simulating the surface of the body of man, and on the known projections determines the magnitude of the vector EMF hearts in three-dimensional space in a given direction.

The projection of the vector EMF of the heart in the frontal plane is defined by the standard leads from limb. The direction of the axes of the lead in this plane are given in degrees. The reference point (0°) conditionally accepted the radius, drawn horizontally from the center of the heart to the left in the direction of the positive pole active I standard lead. For each standard abduction in the frontal plane is defined angle ϕ:

positive pole II standard lead is at an angle of +60°;

positive pole III standard lead is at an angle of +120°;

positive pole lead aVL is at an angle of -30°;

- the positive pole of lead aVF is at an angle +90°;

positive pole of aVR is at an angle -150°.

Electrocardiographic abnormalities in different derivations from the extremities can be seen as different projections of the same EMF heart on the axis data abstraction.

The block diagram of the device for registration of electrocardiogram and define the vector EMF of the heart in a given direction is shown in figure 3. It contains the amplifier 1, analog-to-digital Converter with multiplexer 2, the arithmetic unit 3, the code analyzer increments of 4, the switch unit 5, the digital modem 6, the counter code number increment 7, the first memory unit 8 and the control unit 9, block the formation of the projections of the vector EMF of the heart 10 and the power determination value vector EMF of the heart in a given direction 11. Thus series-connected amplifier 1, an analog-to-digital Converter with multiplexer 2, the arithmetic unit 3, the code analyzer increments of 4, the switch unit 5 and the digital modem 6. Series-connected counter code number increment 7 with the first memory block 8 and block the formation of the projections of the vector EMF heart 10 unit determine the value of the vector EMF of the heart in a given direction 11. The second output of the analyzer code increment 4 is connected to the first input of the first memory unit 8, and control output from the first counter input code number increment 7, a second input connected to the first output control unit 9, the second and third outputs of the latter are connected respectively with the control input of the switch unit 5 and the second analog-digital Converter 2, while the output of the first memory unit 8 is connected with the second input of the switch unit 5, the first input of the processing unit projection vector EMF heart 10 is outinen with the output of the analog-to-digital Converter 2, the second inputs of the processing unit projection vector EMF of the heart 10 and block determine the value of the vector EMF of the heart in a given direction 11 are connected respectively to the third and fourth outputs of the control unit 9, the output unit determine the value of the vector EMF of the heart in a given direction 11 is connected to the third input of the switch unit 5.

The block diagram of the processing unit projection vector EMF heart 10 is shown in figure 4. It contains the first multiplier 12, the first accumulating adder 13, the second multiplier 14, the second accumulating adder 15, the third multiplier 16, the third accumulating adder 17, the second memory unit 18, the first 19 and second 20 inputs and output 21. When connected in series respectively to the first multiplier 12 c first storing the adder 13, the second multiplier 14 with the second accumulating the adder 15, the third multiplier 16 with the third storing the adder 17, the first inputs of the multipliers are connected to the third output control unit 9, second and third inputs of multipliers connected respectively with the output of the analog-to-digital Converter 2 and the output of the second memory unit 18, the outputs of the adders are output processing unit projection vector EMF heart. Block diagram block definition values of the vector EMF of the heart in a given direction 11 is shown in figure 5. It contains the third nl the memory 22, fourth 23, 24 fifth, sixth, 25, 26 seventh, eighth 27, 28 ninth, first, second, third adders 29, 30, 31, 32 tenth, eleventh 33 and twelfth multipliers 34, the fourth adder 35 and the block taking the square root of 36, the first 37 and second 38 inputs and output 39. And the first inputs of the fourth 23, 24 fifth, sixth, 25, 26 seventh, eighth, 27 and 28 ninth multiplier units respectively connected to the outputs of the first 13 and second 15 and third 17 accumulative adders block the formation of the projections of the vector EMF heart, the second inputs of the fourth 23, 24 fifth, sixth, 25, 26 seventh, eighth, 27 and 28 ninth multiplier units connected to the output of the third memory block 22, the outputs 23 and fourth 24 fifth multiplier units are connected respectively with the first and second inputs of the first adder 29, the outputs of the sixth 25 and 26 seventh multiplier units are connected respectively with the first and second inputs of the second adder 30, the outputs of the eighth 27 and 28 ninth multiplier units are connected respectively with the first and second inputs of the third adder 31, the first and second inputs of the tenth block multiplication 32 combined and connected to the output of the first adder 29, the first and second inputs of the eleventh block multiplication 33 United and connected with the output of the second adder 30, the first and second inputs of the twelfth block multiplication 34 United and connected with the third output is about adder 31, first, second and third inputs of the fourth adder 35 are connected respectively to the outputs 32 tenth, eleventh 33 and twelfth 34 multiplier units, sequentially connected to the unit operation to retrieve the root 36 whose output is the output of the block defining the value of the vector EMF of the heart in a given direction 39.

The amplifier 1 is designed for amplification of the signals leads. Analog-to-digital Converter with multiplexer 2 is designed to convert signals lead from analog form into a digital form. The arithmetic unit 3 is intended for forming, for each assignment of the difference between the current and the previous code samples. The code analyzer increments 4 is designed to, first, the separation of the received code increment into two parts: the first part consists of two least significant bits of the code increments and significant digits (3 digits), the second part of the remaining six high-order bits of code increment, and second, to analyze the second part of the received code increment. The switch unit 5 is designed for serial connection of the outputs of the analyzer code increments of 4, the first memory block 8 and block definition vector EMF of the heart in a given direction 11 to the input of a digital modem 6. Digital modem 6 is designed to transmit channel information of the light is I. Count the number of code increments 7 is designed to determine the number of the current code increment. The first memory unit 8 is designed to store the values of the second part of the code increments under the condition different from zero at least one of the discharge. The control unit 9 is designed to synchronize and control the operation of the blocks of the device. Block the formation of the projections of the vector EMF heart 10 is designed to generate values of the projections of the vector EMF heart on the axis of the spatial coordinate system. Block determine the value of the vector EMF of the heart in a given direction 11 is designed to determine the value of the vector EMF of the heart in a given direction.

The first multiplier 12 forming unit projection vector EMF heart 10 is designed to find the vector Ei_oxthe projection of each of the i-th standard leads from the extremities to the OX axis of the spatial coordinate system. First accumulating adder 13 forming unit projection vector EMF heart 10 is designed to find the vector EOhthe sum of the projections of the standard leads from the extremities to the OX axis of the spatial coordinate system. The second multiplier 14 forming unit projection vector EMF heart 10 is designed to find the vector Ei_ozthe projection of each of the i-th standard leads from the extremities to the OZ axis space, Breakfast is the only coordinate system. Second accumulating adder 15 block forming projections of the vector EMF heart 10 is designed to find the vector Eozthe sum of the projections of the standard abstraction from the extremities to the OZ axis of the spatial coordinate system. The third multiplier 16 forming unit projection vector EMF heart 10 is designed to find the vector Ei_OSthe projection of each of the i-th standard chest leads on the OY axis of the spatial coordinate system. The third accumulating adder 17 forming unit projection vector EMF heart 10 is designed to find the vector EOSthe sum of the projections of the standard chest leads on the OY axis of the spatial coordinate system. The second memory unit 18 is used for storing values of the trigonometric functions of the angles of the directions of the axes of the standard leads.

The third memory block 22 block definition values of the vector EMF of the heart in a given direction 11 is used for storing the coefficients needed to find the projections of the vectors EOhEOSEozon a straight line connecting the center of the heart with the point on the body surface (hereinafter referred to guide a straight line, see figure 2). The address of the coefficient is set angles α, β, γthat is fed to the input 38 of the third memory block 22 from the fourth output control unit 9. The fourth multiplier 23 of the block to define the population values of the vector EMF of the heart in a given direction 11 is designed for finding the projection of the vector E Ohthe projection of the guide line in the plane of the HOU. The fifth multiplier 24 units determine the value of the vector EMF of the heart in a given direction 11 is designed for finding the projection of the vector EOSthe projection of the guide line in the plane of the HOU. The sixth multiplier 25 block determine the value of the vector EMF of the heart in a given direction 11 is designed for finding the projection of the vector EOhthe projection of the guide line in the plane xOz. The seventh multiplier 26 block determine the value of the vector EMF of the heart in a given direction 11 is designed for finding the projection of the vector Eozthe projection of the guide line in the plane xOz. The eighth multiplier 27 block determine the value of the vector EMF of the heart in a given direction 11 is designed for finding the projection of the vector EOSthe projection of the guide line in the plane yOz. The ninth multiplier 28 block determine the value of the vector EMF of the heart in a given direction 11 is designed for finding the projection of the vector EOSthe projection of the guide line in the plane yOz. The first adder 29 block determine the value of the vector EMF of the heart in a given direction 11 is designed for finding the projection of the desired vector on the plane of the HOU - Exoy. The second adder 30 block determine the value of the vector EMF of the heart in a given direction 11 PR is naznachen for finding the projection of the desired vector to the plane xOz - Ezox. The third adder 31 unit value definition vector EMF of the heart in a given direction 11 is designed for finding the projection of the desired vector to the plane yOz - Ezoy. The tenth multiplier 32 blocks determine the value of the vector EMF heart 11 is designed for squaring the values of EHOU. The eleventh multiplier 33 block determine the value of the vector EMF heart 11 is designed for squaring the values of Exoz. Twelfth multiplier 34 block determine the value of the vector EMF heart 11 is designed for squaring the values of Ezoy. The adder 35 block determine the value of the vector EMF heart 11 is designed to sum the values of Ewah2Exoz2Ezoy2. Block 36 square root extraction unit determine the value of the vector EMF heart 11 is designed to perform the operation of taking the square root of the sum of squared projections.

The proposed device for recording the FORMER works as follows.

In accordance with the rules of registration of ECG signals standard leads (in the frontal plane denote them Ei_FRand signals chest leads denote Ei_g) are recorded in a specific sequence. The clock pulses from the output of the control unit 9 is transported is t to the input unit 2 and trigger the ADC and the multiplexer, so the output of the ADC 2 and respectively to the inputs of the arithmetic unit 3 and unit formation of the projections of the vector EMF heart 10 codes appear amplitudes EX sequentially in each lead Ei_FRand Ei_g.

The arithmetic unit 3 forms for each of these code samples the difference between the current and the previous reference, and thus to the input of the analyzer code increment 4 flows 8 bit code increment signal with the sign (the 9th bit) sequentially for each abstraction. At the same time from the output of the control unit 9 clock pulses arrive at the counting input of the counter code number increment 7, resulting in the output of the counter 7 is formed code numbers calculated increment signal, i.e. its temporal coordinate. In the code analyzer increments 4 separates the received code increment into two parts; two minor category code increment and its sign bit (just 3 digits) via the input switch unit 5 are transferred directly to the digital modem 6 and further to the communication channel and transmitted to the receiving end. The values of the remaining six high-order bits of code increments are analyzed and if it is different from zero at least one discharge through the output unit 4 of the code analyzer increments of these 6 bits are sent to the input of the first memory block 8, where remember who I am. At the same time under the condition different from zero the analyzer block codes increments 4 generates a write command time coordinates coming from the analyzer 4 to the input of the counter code number increment 7, which is determined by the number of the current code increment (time coordinate). If all 6 high-order bits of the incoming code increment equal to zero, then the two youngest and the sign bit of code increments as before, go on line for transmission, and the code analyzer increments 4 waits for the next code increment.

In block formation of the projections of the vector EMF heart 10 with each clock pulse of the control unit 9 according to the formula:

the first 12 and second 14 multipliers are calculated projection of each of the i-th standard leads from the extremities to the axes OX and OZ spatial coordinate system of the person. The third multiplier 16 defined values of the projection of the vector EMF heart on the OY axis of the spatial coordinate system of a person:

The first 13 and second 15 and third 17 accumulate adders determine the sum of the projections of the vector EMF heart respectively on the axes OX, OZ and OY by the formulas:

The values of these projections unit determine the value of the vector EMF of the heart in a given direction 11 bycicles the value of a vector EMF heart for directions, given angles α, β, γ ratio anisotropicly environment kΩ(smpeg):

The procedure takes place until, until the end of the specified time of registration of the FORMER, which is determined by the duration of the time interval, released by a control unit 9. At the end of the registration interval control unit 9 stops the supply of clock pulses to the inputs of blocks 2 and 7, completing their work. Then the control unit 9 sends the command to the input of the switch unit 5, thereby connecting the input of the modem 6 to the output of the first memory block 8 and starting the transfer of the memory contents, i.e. memorized older bits of code increments and time coordinates. Then the control unit 9 sends the command to the input of the switch unit 5, thereby connecting the input of the modem 6 to the output of the block defining the value of the vector EMF of the heart in a given direction 11 and starting the transmission of the values of the vector EΩ, which represents the projection of the vector EMF heart on the guide line.

According to the authors of the present invention, such processing electrocardiographic information will provide a more complete picture of the distribution of electric what about the potential on the surface of the human body in comparison with the known device. In addition, it should be noted an important feature of the proposed device: determining the distribution of electric potential on the surface of the body is carried out during the Desk electrocardiographic information in real time without additional time delay.

Thus, the proposed registration and processing of ECG extend the functionality of the known device. The extension is achieved by determining the parameters of the FORMER not only in the field of standard lead, but at any given point on the surface of the body. The use of methods of mathematical processing of the FORMER in standard leads allows you to achieve the functional capabilities of the EX-mapping. It increased diagnostic device properties and retained his dignity on the original measurement accuracy ECG.

Literature:

1. Microcomputer medical system. Ed. Tompkins, M.: Mir, 1983, s.

2. Baum O., G. Kostov, L.A. Popov Device for registration of electrocardiogram. Patent RU No. 2008796 C1, MKI5And 61 In 5/0402, 1994.

3. Korn G., Korn T. Handbook of mathematics. Izd-vo "Nauka", 1974.

1. Device for registration of electrocardiogram containing connected in series amplifier, analog-to-digital Converter with multiplexer and Ari is eticheskoe device, and the code analyzer increments, a switch unit, a digital modem, the counter non-code increment the memory unit and the control unit, and the analyzer input codes increment is connected to the output of the arithmetic unit, the first output of the analyzer code increment connected to the first input switch unit, the second to the first input of the memory block, and a control output to the first input of the counter code number increment, a second input connected to the first output control unit, the second and third outputs of the latter are connected respectively with the control input of the switch unit and the second input of the analog-to-digital Converter, and the output of the counter room code increment connected with the second input of the memory block, the output of which is connected with the second input of the switch unit, and the output switch unit with modem input, characterized in that it introduced connected in series forming unit projection vector EMF heart and the power determination value vector EMF of the heart in a given direction, while the first and second inputs of the processing unit projection vector EMF hearts are connected respectively with the third output of the control unit and the output of the analog-to-digital Converter, the fourth output control unit connected with the second input of the block defining the value of the vector EMF when rdca in a given direction, the output of which is connected to the third input of the switch unit.

2. The device according to claim 1, characterized in that the shaping unit projection vector EMF heart contains a second memory block, and connected in series respectively to the first multiplier and the first accumulating adder, connected in series to the second multiplier and the second accumulating adder, connected in series, the third multiplier and the third accumulating adder, the first inputs of the multipliers and the input of the second memory block is connected to the third input of the control unit, second and third inputs of multipliers connected respectively with the output of the analog-to-digital Converter and the output of the second memory block, and the outputs of the adders are output processing unit projection vector EMF heart.

3. The device according to claim 1, wherein the block of determining the values of the vector EMF of the heart in a given direction contains the fourth, fifth, sixth, seventh, eighth, ninth, tenth, eleventh and twelfth multipliers, the first, second, third and fourth adders, the block extracting the root and the third memory block, the third memory block is connected to the fourth output control unit, and the first inputs of the fourth, fifth, sixth, seventh, eighth and ninth multipliers connected respectively to the outputs of the first, the who and the third accumulative adders block the formation of the projections of the vector EF heart, the second inputs of the fourth, fifth, sixth, seventh, eighth and ninth multipliers connected to the output of the third memory block, the outputs of the fourth and fifth multipliers connected respectively with the first and second inputs of the first adder, the outputs of the sixth and seventh multipliers connected respectively with the first and second inputs of the second adder, the outputs of the eighth and ninth multipliers connected respectively with the first and second inputs of the third adder, the first and second inputs of the tenth multiplier combined and connected to the output of the first adder, the first and second inputs of the eleventh multiplier combined and connected to the output of the second adder, the first and second inputs of the twelfth multiplier United and connected with the output of the third adder, the first, second and third inputs of the fourth adder connected respectively to the outputs of the tenth, eleventh and twelfth multipliers, and the output is connected to the operation block root extraction, the output of which is the output of the block defining the value of the vector EMF of the heart in a given direction.



 

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2 cl, 4 dwg

FIELD: medicine; cardiology.

SUBSTANCE: device for registering electric cardiosignals has amplifier, analog-to-digital converter with multiplexer and arithmetic unit as well as increment code analyzer, switch unit, digital modem, increment code number counter, memory unit, control unit, heart electro-motive force vector projection forming unit, heart electro-motive force vector value determination unit and heart electro-motive force vector direction determination unit. Device has widened functional capabilities of electric cartographic testing by means of finding spatial disposition of electric axis of heart. Projection of heart vector to frontal plane is found from standard abstracts from extremities and to horizontal plane - from chest abstracts. Projection of vector of heart to sagittal plane is determined from projections of vector of heart to frontal and horizontal planes. Direction and value of projection of heart electro-motive force is determined from known projections in three-dimensional space.

EFFECT: improved efficiency.

4 cl, 7 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves measuring physical characteristic of body surface. Micro-vibration power is measured in rest state on the body area under study during 0.5-5 min. Device has micro-vibration transducer and spectrum analyzer connected to visual recording device. The micro-vibration transducer is designed as electronic phonendoscope having pass band of 1-300 Hz. The visual recording device records variations of total micro-vibration spectral power in time. Mean micro-vibration power is determined. Its deviation from a reference value being equal to or greater than 40%, pathological process is considered to be available in the zone.

EFFECT: high accuracy in determining vestibular dysfunction cases.

2 cl, 3 dwg

FIELD: medicine; cardiology.

SUBSTANCE: device can be used in clinical and experimental tests for registration; analysis and transmission of electrocardiographic signal. Parameters of electrocardiographic signal are determined at any point of patient's body due to finding projection of vector of electrocardiographic signal of heart at any preset direction. Device has amplifier, analog-to-digital converter with multiplexer, arithmetic unit, increment code analyzer, switch unit, digital modem, increment code number counter, memory and control units, unit for forming projections of vector of electrocardiographic signal of heart and unit for finding value of vector of electrocardiographic signal of heart at preset direction.

EFFECT: widened operational capabilities.

3 cl, 5 dwg

FIELD: medical equipment.

SUBSTANCE: system intends for transmitting cardiologic signals along radio channels; it can be used in hospitals, clinics, for ambulance service and at consultation-diagnostic medical centers. System has equipment for serving patient and control board equipment. Patient serving equipment has electrodes, preamplifier, high frequency first generator, first amplitude modulator, modulating code generator, first phase manipulator, first power amplifier, first receiving-transmitting aerial, second heterodyne, second mixer, first intermediate frequency amplifier, first aerial switch, second power amplifier, third heterodyne, third mixer, second intermediate frequency amplifier, second amplitude limiter, second sync detector, registration unit, multiplier, band-pass filter and second phase detector. Control board equipment has microprocessor, comparison unit, lower and top level's memory units, adjusted threshold unit, alarm signal forming unit, magnet registrar, sound signal unit, second receiving-transmitting aerial, tuning unit, first mixer, second intermediate frequency amplifier, detector, delay line, switch, first amplitude limiter, first sync detector, second delay line, first phase detector, high frequency second generator, analog messages source, second phase manipulator, fourth heterodyne, fourth mixer, intermediate frequency amplifier, third and fourth power amplifiers, second aerial switch. Detector has spectrum width measuring unit, phase doubler, second comparison unit and first threshold unit. Radio channel is used in duplex (two-directional) mode when analog and discrete information is transmitted not only from patient to control board but from control board - to patient or to doctor treating the patient.

EFFECT: improved efficiency.

5 dwg

FIELD: medical engineering.

SUBSTANCE: device has electrodes, preamplifier, microprocessor, memory units of upper and lower level, comparison units, threshold units, unit for producing alarm signal, magnetic recorder, acoustic signalization unit, high frequency generator, amplitude modulator, modulating code oscillator, phase manipulator, power amplifier, transmitting antenna, retuning unit, heterodyne, mixers, intermediate frequency amplifier, detector (selector), amplitude restrictors, synchronous detector, phase detectors, spectrum width measurement units, phase doubler, phase rotator by +90°, adder, multiplier, narrow band filters, amplitude detector, phase divider by 2, phase rotator by +30°, phase rotator by -30° and subtraction units.

EFFECT: improved noise immunity.

3 dwg

FIELD: medical engineering.

SUBSTANCE: system has device for measuring and recording biopotentials, device for measuring and recording movement parameters having the first accelerometer, the second accelerometer, the third accelerometer, the first instrumentation amplifier, the second instrumentation amplifier, the third instrumentation amplifier, multi-channel analog-to-digital converter, microcontroller, long-term storage, the first external interface adapter, timer, data analysis device comprising computer, graphic display unit, the second external interface adapter and system interface backbone. The first, the second and the third accelerometers are connected via the first, the second and the third instrumentation amplifiers to multi-channel analog-to-digital converter input cannels. The analog-to-digital converter is connected to the microcontroller. The microcontroller has long-term storage, external interface adapter and timer. The external interface adapter input/output serves as external interface adapter input/output of the device measuring and recording movement parameters. The device for measuring and recording biopotentials is connected to input channel of the device for measuring and recording movement parameters comprising microcontroller input via the second data transfer channel. The first and the second external interface adapters are connected to each other via the first data transfer channel. The computer and the second external interface adapter are connected to each other via system interface backbone. The graphic display unit is connected to the computer.

EFFECT: wide range of functional applications; high diagnosis accuracy.

7 cl, 1 dwg

FIELD: medicine; obstetrics.

SUBSTANCE: fetal cardiac rhythm is registered. Additionally cardiointervalography is performed with determination of spectral power density of maternal and fetal cardiac rhythm waves and selection of very low frequency VLF, low frequency LF and high frequency HF levels, regulator system tension index TI, cortizol and adrenaline level in maternal and fetal blood. Physiological pregnancy course is defined at adrenaline level of 28 ng/mol, cortizol level of 360 ng/ml, indices of VLF=120 relative units, LF=40 r.u., HF=20 r.u., TI=70 r.u., for the mother and at indices of VLF=25 r.u., LF=2 r.u., HF=1 r.u., TI=250 r.u. for the fetus; compensated form of chronic fetoplacental deficiency is detected at the adrenaline level of 46 ng/ml, cortizol level of 695 ng/ml, VLF=180 r.u., LF=50 r.u., HF=100 r.u., TI=160 r.u. for the mother and at VLF=45 r.u., LF=5 r.u., HF=1 r.u., TI=400 r.u. for the fetus; and decompensated form of chronic fetoplacental deficiency is detected at the adrenaline level of 2 ng/ml, cortizol level of 1003 ng/ml, VLF=900 r.u., LF=25 r.u., HF=10 r.u., TI=30 r.u. for the mother and at VLF=3 r.u., LF=1 r.u., HF=0 r.u., TI=700 r.u. for the fetus.

EFFECT: improved accuracy and information capacity of diagnostics of physiological pregnancy course and chronic fetoplacental deficiency forms.

1 dwg, 9 tbl

FIELD: medicine.

SUBSTANCE: electrodes of electric ECG potential registration are placed in zone of aorta and in zone of cardiac apex. Changes of electric potential on body in time are registered in form of diagram of ECG function. Near each electrode of ECG electric potential registration additional electrode is installed, onto which high-frequency signal from generator is supplied, and from electrodes of ECG electric potential registration modulated by fluctuations of arterial blood flow signal is obtained synchronously, said signal is amplified, converted into digital code and transmitted for rheogram registration to information processing unit, after which connection of ECG electric potential with change of pressure according to rheogram is connected in each phase, and phase peculiarities of arterial pressure change are diagnosed. Device for synchronous registration of rheogram from ECG electrodes consists of two ECG electrodes, commutator, first amplifier, first band filter, analogue-digital converter, controller, IR transmitter and information processing unit with first detector, commutator being inserted between electrodes and first amplifier, whose outlet through band filter is connected with first inlet of analogue-digital converter, whose outlet is joined to controller, whose first outlet is connected with commutator, and second outlet - with IR transmitter, connected with first detector of information processing unit. Two additional electrodes, second amplifier, second band filter, second detector and generator, switched to additional electrodes, are introduced into it, second commutator outlet is connected to inlet of second detector, whose output through second amplifier and second band filter is connected with second inlet of analogue-digital converter.

EFFECT: synchronous registration of phase characteristics of cardiac cycle and corresponding fluctuations of arterial pressure in heart vessels and aorta.

2 cl, 3 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to devices of medico-biological purpose, intended for registration and evaluation of fast-proceeding physiological reactions, emerging as response to produced stimuli. Device contains microcontroller, analogue-digital converter (ADC), first commutator, sensors of breast breathing, abdominal breathing, skin-galvanic response, arterial pressure, cardio-vascular activity, sensor of motor activity, power unit, preliminary amplifiers, signal amplifiers, filters, first and second digital-analogue converters (DAC), tool amplifier and unit of connection with personal computer, supplied with galvanic attenuator. Via amplifiers and filters sensors are connected with corresponding inputs of commutator whose controlling input is connected with first microcontroller bus, and output - with first input of tool amplifier. Second input of tool amplifier is connected to output of first DAC, third input - to output of second DAC, and output - to ADC input. Inputs of first and second DAC and group of inputs-outputs of ADC are connected with second microcontroller bus, whose third bus is connected to unit of connection with personal computer. Additional channel has possibility of connection to its input of face mimics sensor, piezoplethysmogram or variable component of skin-galvanic response and includes second electronic commutator, to whose outputs subchannels of processing of signals from corresponding sensor are connected. First subchannel includes successively connected preliminary amplifier and filter, second subchannel - preliminary amplifier, filter, signal amplifier and additional filter, and outputs of subchannels via third electronic commutator are connected to first commutator input. Controlling input of third commutator is connected with microcontroller.

EFFECT: registration of maximal number of physiological parametres and ensuring objectivity of obtained information.

2 cl, 2 dwg

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