Four-electrode unit for reading cardio-respiratory parameters of biological object

FIELD: medical equipment; veterinary equipment.

SUBSTANCE: device is used for measurement of volumetric parameters of breathing and electrocardiogram by methods of impedance pneumography and electrocardiography. Device is intended for physiological testing under natural conditions of life and activity of patient - at work, in sports, at home as well as at checking of natural conditions of maintenance and existence of animals. Device has two generator and two signal electrodes, stable ac generator and two filters. First filter is intended for selecting cardiographic signal and the second one - for selecting respiratory signal. Stable ac generator is made with symmetrical differential output. Two T-shaped units are introduced into circuit of connection of mentioned generator with generator electrodes. Two resistors, connected in series, of first and second T-shaped unit are connected to circuit of connection of first (second) generator electrode with output of generator. Passive member (resistor or inductance) of any T-shaped unit is connected between point of connection of two resistors from the unit and case of device. Four dischargers and two resistors are additionally introduced into four-electrode device.

EFFECT: improved noise immunity for co-phase error: widened area of application.

4 cl, 2 dwg

 

The invention relates to medical and veterinary equipment, namely, devices for measuring and recording the parameters of biological objects (humans, animals) - volume parameters of respiration and electrocardiogram methods respectively impedance pneumography and electrocardiography. The invention is intended for use in physiological studies in natural conditions and human activities - at work, in sports, in life and in natural conditions (life) animals.

Known multielectrode device for removal cardiorespiratory parameters of the bio-object [J.Fradin e.a. A dry electrode monitoring system. - IEEE/Eng.Med. and Biol. Soc. 41-st Ann. Conf. Denver, Colo, 1979, N.Y. 1979, p.p.36-39], which contains two generators and two signal electrodes, and two common electrodes, circuit connections of the first generator electrode with the first output terminal of the generator stable alternating sinusoidal current contains sequentially switched capacitor, a second generator electrode is connected directly with the second output terminal of the generator stable AC, and alternator stable AC has a single-ended output, the first signal electrode is connected directly to the first input terminal of the channel broadband amplification removed from the bio-object signals, the second is ignaliny electrode is connected directly with the second input terminal of broadband amplification remove with the bio-object signals, channel broadband amplification removed from the bio-object signals includes serially connected first and second amplification stages removed from the bio-object signals, with the output of the first of the above stages is connected to the input of the channel compensation common mode noise, the output of which is connected with one of the common electrodes, the second common electrode is connected to the housing (shared bus) device, the output of the second amplification stage is removed from the bio-object signals connected to two filters, each of which is designed to highlight one of the retiring of the bio-object signals, namely, surgical and respiratory signals.

Use the specified device generator stable AC allows precision measurements of the parameters of the bio-object (in this case the frequency of breathing). In General, the use of stable generator of alternating current allows the precise measurement of all parameters of external respiration of humans and animals. Special payment channel common mode noise that interfere with the measurement of the electrocardiogram, protects the device from interference resulting from changes in electrode impedance when the movements of the bio-object and external electromagnetic interference, in particular, interference from industrial power supply.

One is on this device does not provide protection against external electromagnetic interference, placing the circuit connecting the output of the generator stable AC generator electrodes and released on the nonlinear elements of the generator. Such interference occur, especially when using the device for removal cardiorespiratory parameters of the bio-object in natural conditions, in particular when biotelemetry research of parameters of biological objects in the field of physiology and hygiene at work.

The disadvantage of this known device is also increased complexity due to the increased amount placed on the bioobject electrodes (six electrodes) and any special payment channel interference. This introduces difficulties in the maintenance of this device increases the requirements for service personnel and leads to increased cost of manufacture and operation. Practically these circumstances exclude the application of the device in vivo activity of biological objects. In addition, the circuit construction of the device precludes the use of the defibrillator and/or the electrosurgical instrument with simultaneous removal of the parameters of the bio-object, as, for example, simultaneous use of the defibrillator causes the unit to fail due to exposure to high is atragene defibrillator, arriving at the inputs of the device through imposed on bioobjects electrodes. All specified limits the scope of use of the known device.

Closest to the proposed technical solution (prototype) is [M Qu e.a. Motion artifact from Spot and Band Electrodes During Impedance Cardiography. - IEEE Transaction on BME, 1986, BME-33, #11, November, p.p.1029-1036] four-electrode device for removal cardiorespiratory parameters of the bio-object, containing two generators and two signal electrodes, circuit connections of the first generator electrode with the first output terminal of the generator stable AC contains series-connected first capacitor, the circuit connection of the second generator electrode with the second output terminal of the generator stable AC contains series-connected second capacitor, and a stable generator of alternating current has a single-ended output, and the signal electrodes are connected to the inputs of two filters, each of which is designed to select one from a shoot with the bio-object signals, namely, capacitive-resistive high-pass filter selection respiratory signal and resistive low pass filter selection cardiographic signal, with the output of each filter selected signal is sent to the corresponding channel gain of this signal.

Reduced immunity to external electromagnetic interference, especially in a production environment, limits the scope of use of the known device the prototype.

In addition, the schematic construction of a device prototype excludes the use of the defibrillator and/or the electrosurgical instrument with simultaneous removal of the parameters of the bio-object, as the high voltage defibrillator or the electrosurgical instrument and the resulting currents of large magnitude acting on the body of the patient through the electrodes of the device affect the circuit device, disabling its elements, the normal operating voltages and currents which are significantly less than the voltages and currents of the defibrillator and electrosurgical instrument. It also restricts the use of the known device the prototype.

The objective of the proposed invention is to increase the noise immunity at the trojstva and the expansion of its use.

This problem is solved by two variants of the invention.

To solve this task according to the first variant of the four-electrode device for removal cardiorespiratory parameters of the bio-object, containing two generators and two signal electrodes, the circuit connection of the first output terminals of the generator stable alternating current with the first generator electrode circuit connection of the second output terminals of the generator stable alternating current with the second generator electrode, the signal electrodes are connected to the inputs of two filters, the first of which is intended to highlight cardiographic, and the second respiratory signals, characterized in that the generator is stable AC is made with symmetrical differential output, the midpoint of which is the third output terminal of the specified generator and is connected to the housing device, and first and second output terminals of the generator terminals are symmetrical differential output of the generator, in addition, the device is introduced first, second, third and fourth resistors, and first and second passive elements, each of which can be either a resistor or inductance, and the first and second resistors and the first passive element form a first T-shaped link, and the third and fourth resist the s and the second passive element form a second T-shaped link, each of these T-shaped links included in the link circuit, respectively, the first or second output terminals of the generator stable alternating current to the first or second generator electrode so that two series-connected resistors of the first and second T-shaped link included respectively between the second output of the first (second) capacitor and the first (second) generating electrode, and the passive element of each T-shaped element connected between a connection point between two resistors of this link and the housing of the device, each of the passive elements of each T-shaped element has a resistance of at least five times the output impedance of the generator is stable AC.

Four-electrode device for removal cardiorespiratory parameters of the bio-object in the first embodiment also differs in the fact that it introduced the first, second, third and fourth gaps, as well as added the fifth and sixth resistors, the first spark gap connected between the connection point between the first and second resistors of the first T-shaped link and the housing of the device, the second spark gap is similarly incorporated into the second T-shaped link, each of the two added resistors connected in series in a circuit connected to the I signal electrode to the input of one of the filters so the first output of each added resistor is connected directly with one of the signal electrodes, the second output of each added resistor connected to the input of one of the filters, the third spark gap connected between the device and the second output of one of the added resistor, and the fourth gap is included between the device and the second output of the other of the added resistors.

In addition, four-electrode device for removal cardiorespiratory parameters of the bio-object in the first embodiment differs in that each of the passive elements of each T-shaped element has a resistance at least five times the output impedance of the generator is stable AC.

To solve this task according to the second variant of the four-electrode device for removal cardiorespiratory parameters of the bio-object, containing two generators and two signal electrodes, the circuit connection of the first output terminals of the generator stable alternating current with the first generator electrode circuit connection of the second output terminals of the generator stable alternating current with the second generator electrode, the signal electrodes are connected to the inputs of two filters, the first of which is for you the population cardiographic, and the second respiratory signals, characterized in that the generator is stable AC is made with symmetrical differential output, the midpoint of which is the third output terminal of the specified generator and is connected to the housing of the device, and first and second output terminals of the generator terminals are symmetrical differential output of the generator, in addition, the device is introduced first, second, third, fourth, fifth and sixth resistors, the first and second passive elements, each of which can be either a resistor or inductance, and also introduced the first, second, third and fourth gaps, and the first and second resistors and the first passive element form a first T-shaped link, and the third and fourth resistors and the second passive element form a second T-shaped link, each of these T-shaped links included in the link circuit, respectively, the first or second output terminals of the generator stable alternating current to the first or second generator electrode so that two series-connected resistors of the first and second T-shaped link included respectively between the second output of the first (second) capacitor and the first (second) generating electrode, and the passive element of each T-shaped link connected between the accoi connection between the two resistors of this link and the housing of the device, stable AC, the first spark gap connected between the connection point between the first and second resistors of the first T-shaped link and the housing of the device, the second spark gap is similarly incorporated into the second T-shaped link, the fifth and sixth resistors are switched on one by one sequentially in the circuit connection of the signal electrode to the input of one of the filters so that the first output of the fifth (sixth) resistor is connected directly with one of the signal electrodes, the second terminal of the fifth (sixth) resistor connected to the input of one of the filters, the third spark gap connected between the device and the second output of the fifth resistor and the fourth gap is included between the device and the second output of the sixth resistor.

In addition, four-electrode device for removal cardiorespiratory parameters of the bio-object according to the second variant differs in that each of the passive elements of each T-shaped element has a resistance at least five times the output impedance of the generator is stable AC.

The implementation of the proposed device according to the first embodiment of the generator stable AC symmetrical differential output introduction to the operation of the four resistors and two passive elements while the above is soedinenii all elements of the device provides unexpected technical result - increasing pomeganate in-phase for all electrodes interference, which is especially important for electrocardiographic signal as the dominant common-mode interference is a network disturbance with a frequency of 50-60 Hz, which is in the spectrum of the ECG signal. In addition, the proposed circuit design device according to the first variant provides the possibility of introducing a scheme of protective elements in the form of gaps, allowing the use of the defibrillator and/or electrosurgical instrument with simultaneous removal of the parameters of the bio-object. The use of the device is expanded, it can be used for removal of cardiorespiratory parameters of interest in the natural conditions of labour and sports activities during the rehabilitation procedures in postinfarction observations, and survey of animals in terms of free movement on the farms.

The introduction of the proposed device according to the first variant of the first, second, third and fourth gaps, and two additional resistors when the above combination of these elements provides the opportunity to use the device in the first embodiment with a defibrillator or electrosurgical instruments without removing the measurement scheme, without disturbing the measurement process, and without the need the cost of removing the electrodes from the patient's body. This is ensured by the fact that the high voltage defibrillator or electrosurgical element and acting on the patient's body currents discharged from the circuits of the device through the specified gap.

The implementation of the proposed device according to the second variant of the generator stable AC symmetrical differential output introduction to the operation of six resistors, two passive elements and the four gaps in the above connection of all elements of the device provide the same effect as in the first embodiment of the invention is to increase the noise in the common mode for all electrodes interference. In addition, ensure the normal operation of the device according to the second variant, while the application of the defibrillator or the electrosurgical instrument without disconnecting measurement scheme, without disturbing the measurement process and without having to remove the electrodes from the patient's body. The proposed device can be used for removal of cardiorespiratory parameters of interest in the natural conditions of labour and sports activities during the rehabilitation procedures in postinfarction observations, and survey of animals in terms of free movement on the farms.

Giving in four-electrode device for removing cardiorespiratory parameters of the bio-object on any variant of each of the passive elements of each T-shaped link Velikiy resistance, at least five times the value of the output resistance of the generator stable alternating current, provides the minimum bypass output of the generator is stable AC.

In the prior art is not identified technical solutions containing the above-mentioned aggregate restrictive and distinctive features of independent claims that while achieving the above technical result allows to consider the proposed technical solutions involve an inventive step. Unity of invention is provided by the presence in both variants of the invention similar features to achieve the same technical result - increased robustness of the device.

The invention is illustrated by drawings:

figure 1 - block diagram of the proposed four-electrode device for removal cardiorespiratory parameters of the bio-object transformer symmetric differential output of the generator is stable AC;

figure 2 - transformer-less execution symmetric differential output of the generator is stable AC.

Four-electrode device for removal cardiorespiratory parameters of the bio-object contains (1) two generator 1, 2 and two signal electrodes 3, 4. When operating ustroystvo.ranee electrodes mounted on the bioobject 5, which is, in particular, the patient's body. The circuit connection of the first output terminals 6 generator 7 stable alternating current with the first generator electrode 1 contains connected in series (cascaded) of the first capacitor 8, the first and second resistors 9 and 10. The first output capacitor 8 is connected to the first output terminal 6 generator 7, the second terminal of the capacitor 8 is connected to the first output resistor 9, the second terminal of which is connected to the first output resistor 10, and the second output resistor 10 connected to the generator electrode 1. The circuit connection of the second output terminal 11 of the generator 7 with the second generator electrode 2 has consistently enabled (United) the second capacitor 12, the third resistor 13 and the fourth resistor 14, and the first output capacitor 12 is connected to the first output terminal 11 of the generator 7, the second terminal of the capacitor 12 is connected with the first output resistor 13, the second terminal of which is connected to the first output resistor 14, and the second output resistor 14 is connected to the generator electrode 2.

Each of the output terminals 6, 11 of the generator 7 is connected with the corresponding output of the secondary winding 15 of an output transformer of the generator 7. The primary winding 16 of the transformer connected to the generator 17 AC signal, which is, for example, has sinusoidal the tion generator (see figure 2, in figure 1 is not shown). Midpoint 18 of the secondary winding 15 is connected to the third output terminal 19 of the generator 7 and the housing of the device. Thus, the generator 7 has a symmetrical differential output.

The first passive element 20 (resistor or inductance) is included between the device and a common point 21 of the connection between the respective terminals of the resistors 9 and 10. The second passive element 22 (resistor or inductor) are also included between the device and a common point 23 of the connection between the respective terminals of the resistors 13 and 14. The resistors 9, 10 and the passive element 20 form a first T-shaped link, and resistors 13, 14 and the second passive element 22 form a second T-shaped link. Thus, each of these T-shaped links included in the link circuit, respectively, the first or second output terminals 6, 11 generator 7 stable alternating current to the first or second generator electrode 1, 2 so that two series-connected resistors of the first or second T-shaped link (9 and 10, or 13 and 14) respectively included between the first (second) capacitor 8 (12) and the first (second) generating electrode 1 (2).

The first spark gap 24 is included between the device and a common point 21 of the resistors 9, 10 of the first T-shaped link and the second discharger 25 included m is waiting for the device and a common point 23 of the resistors 13, 14 the second T-shaped link.

Each of the passive components 20, 22 of each T-shaped element has a resistance at least five times the output impedance of the generator 7 stable AC. This is due to the need for a minimum bypass output of the generator 7. In a particular embodiment of the device when the output impedance of the generator 7, is equal to 10 ohms, each of the resistors 20 and 22 (passive elements) had a resistance 51 or 46 ohms, each of the resistors 9,13 had a resistance of 10 ohms, and each of the resistors 10,14 - 5,6 kOhm.

The signal electrodes 3, 4 are connected to the inputs of two filters 26, 27, the first of which is the low pass filter 26 is designed to highlight the cardiographic signal and the second high pass filter 27 - respiratory signal.

In the circuit connection of the signal electrodes 3, 4 to the inputs of filters 26, 27 included 28 fifth and sixth resistors 29. The input of each of the filters 26, 27 has two input terminals (respectively, 30 and 31, 32 and 33). The first output resistor 28 is connected with the signal electrode 3, the second terminal of resistor 28 is connected with the input terminal 30 of the filter 26 and to the input terminal 32 of the filter 27. The first output resistor 29 is connected with the signal electrode 4, the second terminal of the resistor 29 is connected with the input terminal 31 of the filter 26 and to the input terminal 33 of the filter 27. That is, each re is Vtorov 28, 29 connected in series in the circuit connections of the respective signal electrodes 3, 4 to the input of one of the filters 26, 27. The third spark gap 34 is included between the device and the second output of one of the resistor 28, and the fourth spark gap 35 is included between the device and the second output resistor 29.

The outputs of filters 26, 27 are the outputs of the four-electrode device for removal cardiorespiratory parameters of the bio-object 5 and are connected to the inputs of channels of amplification and registration cardiographic and respiratory signals (not shown).

The filter 27 is a high-pass filter selection respiratory signal, the filter 26 is a low-pass filter selection cardiomegaly. The filter type is due to the fact that cardioseal contains a range of frequencies up to 100 Hz, the respiratory signal up to 100 kHz.

Capacitive-resistive l-shaped filter 27 includes a capacitor 36 connected between the input terminal 32 of the filter and the output terminal 37 of the filter capacitor 38 connected between the input terminal 33 of the filter 26 and output terminal 39 of the same filter, and the resistors 40, 41, connected in series to each other between the connection points of the capacitors 36, 38 with the output terminals 37, 39 of the filter 27. A common connection point between the resistors 40, 41 is connected to the housing of the device and can show the I of the third input-output terminal of the filter 27.

Resistive-capacitive T-shaped filter 26 is connected in series resistor 42 and a resistor 43 connected between the input terminal 30 of the filter 26 and output terminal 44 of the filter serially connected resistor 45 and resistor 46 connected between the input terminal 31 of the filter 26 and the output terminal 47 of the same filter. In each of these pairs resistor-resistor (42-43 and 45-46) one of the conclusions of the first resistor (42, 45) is connected with an input terminal (30, 31), and one of the conclusions of the second resistor (43, 46) connected to the output terminal (44, 47). Other terminals of these resistors of each pair are interconnected. The filter 26 also includes a series-connected with each other capacitors 48, 49 connected between the common connection points between the resistors of each of the above-mentioned pair of resistors. A common connection point between the capacitors 48, 49 is connected to the housing of the device and can be a third input-output terminal of the filter 26.

The generator 7 stable AC symmetrical differential output can be transformer-less output. In this case, the generator 7 can include, for example (figure 2), the generator 17 AC signal, one output 50 which is connected to the housing of the device, the second terminal 51 is connected to the base 52 of transistor 53 of the output stage of the generator 7. The manifold 54 is of transistor 53 through a resistor 55 is connected to terminal 56 of the power supply device and through a capacitor 57 is connected to output terminal 6 of the generator 7. The emitter 58 of transistor 53 through a resistor 59 is connected to the housing of the device and through a capacitor 60 is connected to the other output terminal 11 of the generator 7. The housing of the device and then run the generator 7 is connected to the third output terminal 19 of the generator 7.

Simultaneously with the withdrawal of the parameters of the respiratory signal and cardiomegaly of the bio-object 5 can be used if necessary defibrillator or electrosurgical instrument 61 (figure 1)that are connected to special electrodes 62, 63, posted on the bioobject 5. When there is no need to use a defibrillator (ESU) 61 of the circuit device are eliminated gaps 24, 25, 34, 35. In this case, the circuit device may also be excluded resistors 28, 29.

The capacitors 8 and 12 (figure 1) are not mandatory elements of the device, as in the circuit of figure 1 windings 15 and 16 of the output transformer of the generator 7 perform the role of galvanic isolation of bioobject 5 and the device.

Passive elements 20, 22 can be made either in the form of resistors or inductances. As the gaps 24, 25, 34, 35 can be used neon lamp (for example, of the type SI-1) or diode (led chain).

The stability of the amplitude of the alternating voltage generator 7 is required in this case from the point of view of providing what echnosti removal (measurement) cardio - respiratory signals of the bio-object 5. The AC output of the generator 7 can be in the form of a sine wave or other types, for example, square wave, sawtooth voltage. The frequency generator 7 is tens of kHz (in particular, 100 kHz).

If necessary, the output of the generator 7 is connected to the channels of amplification and processing of respiratory and kardiosignalas (not shown) to provide synchronous detection (demodulation) of these signals in these channels, as is done, for example, in the device according to A.S. USSR №819742.

Four-electrode device for removal cardiorespiratory parameters of the bio-object works as follows.

At the output terminals 6, 11 included generator 7 is the stable alternating current Igenethat through the T-shaped links of the elements 9, 10, 20, 13, 14, 22 is transmitted to the generator electrodes 1, 2 and flows through the biological object 5. The magnitude of the variations useful respiratory signal on the signal electrodes 3, 4, proportional to the oscillations of the impedance of the biological object 5, is directly proportional to the amount of current of the generator 7, which thus provides an increased amplitude of the useful respiratory signal. The magnitude of the variations useful cardiomegaly on the signal electrodes 3, 4 is provided by the body of the bio-object 5 as the generator voltage.

Common-mode interference, navodaya on biological object 5, n is an example, interference with the network frequency of 50 Hz, acts between two generator 1, 2 and two signal 3, 4 electrodes. Generating electrodes 1, 2 and resistors 10, 20, and resistors 14, 22 form for this common mode noise is relatively low impedance circuit, which is a virtual shared bus for cardiomegaly. The presence of this virtual bus ensures that the values of the specified common-mode interference on both the signal electrodes 3, 4 relative to the housing of the device. The equality of these values common mode noise relative to the housing of the device results in a zero difference between them on one signal electrode (1) relative to another signal electrode (2). While specified common-mode interference is not present on the terminals 32, 33 and the terminals 30, 31, which are the inputs of the filters 27, 26. As a result, the signal electrodes 3, 4 applies a signal reflecting the parameters of cardiomegaly and respiratory signal and does not contain common mode noise. Using the filter 26 of this signal is a component corresponding to cardiomegaly, and the output terminals 44, 47 filter 26 operates the voltage UECGreflecting the parameters of cardiomegaly. Using the filter 27 from the specified signal is a component corresponding to the respiratory signal, and the output terminals 37, 39 of the filter 27 is effective voltage UIPGreflecting the parameters of the respiratory signal.

Simultaneously with the withdrawal of the parameters of the respiratory signal and cardiomegaly of the bio-object 5 can be used if necessary defibrillator or electrosurgical instrument 61 (figure 1). When switched on, for example, defibrillator 61 and feed on bioobjects high voltage this is the voltage across the electrodes 1, 2, 3, 4 and restrictive resistors 10, 14, 28, 29 is supplied to the gaps 24, 25, 34, 35. Dischargers work, shunting the output of the generator 7 and the inputs of the filters 26, 27 and limiting the amplitude of the high voltage defibrillator 61 to a level safe for the elements of the device.

1. Four-electrode device for removal cardiorespiratory parameters of the bio-object, containing two generators and two signal electrode, the first circuit connection of the first output terminals of the generator stable alternating current with the first generator electrode, the second circuit connection of the second output terminals of the generator stable alternating current with the second generator electrode, the signal electrodes are connected to the inputs of two filters, the first of which is intended to highlight cardiographic, and the second respiratory signals, characterized in that the generator is stable AC is made with symmetrical differential output, the midpoint of which is the third output terminal is specified the second generator and is connected to the housing of the device, and the first and second output terminals of the generator terminals are symmetrical differential output of the generator, the first and second circuit connections are made on the first, second, third and fourth resistors, and first and second passive elements, and first and second resistors and the first passive element form a first T-shaped link, and the third and fourth resistors and the second passive element, the second T-shaped link, with two series-connected resistors each of the T-shaped links connected between the respective first (second) output terminal of the generator stable AC and the first (second) generator electrode, and the passive element of each T-shaped element connected between a connection point between two resistors of this link and the device.

2. The device according to claim 1, characterized in that it introduced the first, second, third, and fourth gaps, as well as the fifth and sixth resistors, the first and second spark gap connected between the connection point between the first and second resistors of the respective T-shaped element and a housing of the device, and the fifth and sixth resistors connected between the respective signal electrode and the input of the corresponding filter, and the third and fourth gaps included between the device and the WMO is Ohm matching filter.

3. The device according to claim 1 or 2, characterized in that each of the passive elements of each T-shaped element has a resistance at least five times the output impedance of the constant current generator.

4. The device according to claim 1, characterized in that the passive elements are in the form of resistors or inductances.



 

Same patents:

FIELD: medicine; cardiology.

SUBSTANCE: method allows registering differential sphygmograms by means of computer and piezoelectric transducer providing high precision. Registration is carried out continuously and doesn't take much labor input. On the base of sphygmograms by using method of finding of "coding" points, two main characteristics of heart beat rate can be found by express analysis. Two main characteristics have to be rhythm and pulse oscillations of arterial pressure induced by periodical throwing of shock volume of blood into aorta. Algorithm of data processing which is developed on purpose, provides automatic placing of "coding" (received on the base of calculation) points onto averaged graph of cardiologic cycle that provides higher precision of determination of amplitude-time parameters at any recognized normal pulsation of selected fragment of pulsogram together with additional visual correction of localization of those points. Fragment of pulsogram with duration of no less than 2 minutes (standard duration equals to 5 minutes) is used for measuring and analyzing time factors which characterize rhythm of heart beating and its variability. After that the calibration factor is calculated to transfer conditional units of computer "digitization" into common units of measurement of blood arterial pressure (in mm of mercury column) and values of pulsation increase in blood arterial pressure in mm of mercury column are determined by integrating cardiologic cycles at selected fragment of pulsogram for corresponding areas. The meanings achieved are used for calculating all the amplitude-time cardiologic hemo-dynamic factors which depend on blood arterial pressure and which characterize systole of myocardium of left ventricle and elastic-resilient properties of walls of arterial channel. Continuous monitoring of changes in amplitude-time factors of pulsogram is provided as well as practically real time scale of getting of all the computational data and quick performance of all the mathematical transformations for making spectral analysis of variability of heart beat rate and selected amplitude-time cardiologic hemo-dynamic factors to determine their total and differential spectral power of oscillations. Results of static and spectral analysis of variability of measured parameters the functional condition and character of vegetative regulation of cardio-vascular system are estimated due to comparison of measured values with average statistical numerical values of the same factors which were specified for cardio-vascular system in relation to age, sex, state of health and signs for groups of people chosen as a test group.

EFFECT: improved precision; widened number of informative factors for estimation of cardio-vascular system.

8 dwg, 2 tbl

FIELD: medical equipment.

SUBSTANCE: device can be used in practical and sports medicine. Device has breath detector and pulse rate detector, clamp having ability of fastening to frame of glasses, joint mounted onto clamp, unit in form of clip for placing light source and photo-resistor which both are parts of pulse rate detector, and pipe. Breath thermal detector is mounted at one end of pipe. The pipe is mounted in clamp for displacement to control position of breath detector in projection of jet of breath-out air. Pulse rate detector is connected with joint through flexible wires. Wires of thermal detector are placed inside pipe. Pulse rate detector and breath detector are connected with corresponding amplifiers through joint. Output of any amplifier is connected with commutator.

EFFECT: simplified design; improved comfort for patient.

2 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves recording patient electrocardiogram in maximum comfort state in one lead and photopletysmogram. Vascular tone index (VTI) is measured as time interval from next in turn R-tooth peak to the next following pulse oscillation. Set of values is built and statistically processed. Mode value MoVTIR is calculated as patient rest state characteristic to estimate current functional state of patient regulation and control systems. Electrocardiogram in maximum comfort state is recorded in one lead and photopletysmogram at the same time. A set of RR-intervals and time intervals from next in turn R-tooth peak to the next following pulse oscillation is built and statistically processed. Amo, Mo and MoVTI values are calculated to estimate current functional state of patient. Neighboring cardio-interval values are additionally measured and mean square deviation MSDP is calculated and then variational pulse ametria SAT index is calculated from formula SAT=0.1 x Mo/MSDP and integral regulation and control system stress index of patient (IRCSS)is calculated from formula IRCSS=(SAT) x [1+(Movtir-MoVTI)MoVTI. Patient organism regulation and control system state is estimated as one corresponding to normative neuropsychic stress characteristic for rest state or when working without significant psychic tension with IRCSS value being within interval from 40 to 300, working neuropsychic stress characteristic for significant tension belonging interval from 300 to 900. Neuropsychic overstress showing necessity of rest belongs to an interval from 900 to 3000. Neuropsychic overstress threatening health belongs to an interval from 3000 to 10000. Attrition showing emergency of escaping from the current state with obligatory cardiologist advice takes place when the value is greater than 10000. The device has unit for recording electrocardiogram, data processing unit and calculation unit connected to estimation unit with its output and unit for recording pulse oscillations, analog-to-digital converter unit having inputs connected to electrocardiogram-recording unit and pulse oscillations-recording unit outputs and its output are connected to calculating unit inputs via the data processing unit, and display unit for showing patient regulation and control systems state. Units for processing and calculating are manufactured on microprocessor base. Signals are form on exit from the microprocessor, their values being corresponding to integral regulation and control system stress index value of a patient(IRCSS). The unit for recording pulse oscillations is designed as electronic transducer set on patient finger. The unit for recording electrocardiogram, records cardiac pulses in single lead.

EFFECT: high accuracy in estimating functional state of human organism regulation and control system.

3 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: method involves recording peripheral differential upper extremity blood vessel rheogram and phonocardiogram in synchronous way. The second phonocardiogram beginning and the deepest rheogram points are detected. Pulse way propagation time reduction being found, arterial bloodstream tone growth conclusions are drawn.

EFFECT: high reliability of the results.

18 dwg, 3 tbl

FIELD: medicine, anesthesiology-resuscitation, traumatology, surgery.

SUBSTANCE: according to 4-point scale one should evaluate the state of 10 clinical, hemodynamic and instrumental values in patients: patient's skin by detecting its color and moisture; hemodynamic values: heart rate, systolic arterial pressure, central venous pressure, shock index; central nervous system by studying the value of Glasgow scale; respiratory system - the frequency of respiratory movements and blood saturation; cardio-vascular system - myocardial necessity in oxygen. Each value has its own point, moreover, 0 points corresponds to that fact that the index under inspection is within age standard, 1 point - when physiological parameters at rest are different against the standard, but their functions are compensated by organs of one or two systems, 2 points - compensation is kept due to alterations in more than 2 systems and it reaches its peak, 3 points correspond to adaptation failure or affected function of one or several systems, and the sum of points being 0-4 in patients one should diagnose the absence of hemorrhagic shock, at 5-9 points - the severity of hemorrhagic shock corresponds to degree I, at 10-19 points - to degree II, at 20 points and more - to degree III.

EFFECT: higher efficiency and accuracy of diagnostics.

4 ex, 1 tbl

FIELD: medical engineering.

SUBSTANCE: selected reference point in every cardiac cycle on TP-segment. Values of neighboring N=2n+1 reference points also belonging to TP-segment are recorded, n=1,2,…, beginning from the first reference point. Other reference points are set to zero. The central reference point value is left without changes in a group of 2n+1 member. Reference point values of each of n pairs of reference points symmetrically arranged relative to the central reference point are scaled relative to condition Uj=U0Kj, where U0 is the central reference point amplitude, Uj is amplitude of j-th reference point pair, j=1,2,…,n is the number of each reference point pair relative to the central reference point, Kj is the scaling coefficients determined from received signal suppression condition of the first n spectral zones in spectrum. The so formed electrocardiogram signal reference point groups sequence is let pass through lower frequency filter with isoline drift signal being obtained being produced on output. The signal is amplified and subtracted from the initial electrocardiogram signal that is preliminarily delayed for lower frequency filter delay time. Device has the first lower frequency filter, discretization unit and unit for selecting anchor reference points connected in series, as well as subtraction unit, unit for saving N reference points, scaling unit, the second lower frequency filter, amplifier and delay unit. Output of the unit for selecting anchor reference points is connected to the first input of memory unit the second input of which is connected to discretization unit output. Each of N memory unit outputs is connected to one of N inputs of scaling units. Scaling unit output is connected to the second lower frequency filter input which output is connected to amplifier input. Amplifier output is connected to the first input of subtraction unit, the second output of subtraction unit is connected to delay unit output. Its input is connected to output of the first lower frequency filter. Subtraction unit output is the device output.

EFFECT: reliable removal of isoline drift.

2 cl, 8 dwg

FIELD: medicine.

SUBSTANCE: method involves recording electrocardiogram and cardiorhythmogram on the background of medicamentous therapy beginning from 7-10 day of the disease. The cardiorhythmogram is shown to the patient. Respiratory training session is carried out. Inspiration and expiration are to be equal in duration, each making Ѕ of cardiorhythmogram breathing wave.

EFFECT: enhanced effectiveness of treatment.

2 cl, 3 tbl

FIELD: medicine.

SUBSTANCE: method involves measuring cardio- and hemodynamic values, calculating estimates of the values and displaying the estimates on monitor. Measuring and calculating each cardio- and hemodynamic value is carried out during basic periods of their oscillations corresponding to heart contraction cycle and respiratory cycle related to absolute time.

EFFECT: high accuracy of estimation.

4 dwg, 1 tbl

The invention relates to contactless investigation of the functional state of the cardiovascular system in the electromagnetic field, harmless to humans

FIELD: medicine.

SUBSTANCE: method involves measuring cardio- and hemodynamic values, calculating estimates of the values and displaying the estimates on monitor. Measuring and calculating each cardio- and hemodynamic value is carried out during basic periods of their oscillations corresponding to heart contraction cycle and respiratory cycle related to absolute time.

EFFECT: high accuracy of estimation.

4 dwg, 1 tbl

FIELD: medicine.

SUBSTANCE: method involves recording electrocardiogram and cardiorhythmogram on the background of medicamentous therapy beginning from 7-10 day of the disease. The cardiorhythmogram is shown to the patient. Respiratory training session is carried out. Inspiration and expiration are to be equal in duration, each making Ѕ of cardiorhythmogram breathing wave.

EFFECT: enhanced effectiveness of treatment.

2 cl, 3 tbl

FIELD: medical engineering.

SUBSTANCE: selected reference point in every cardiac cycle on TP-segment. Values of neighboring N=2n+1 reference points also belonging to TP-segment are recorded, n=1,2,…, beginning from the first reference point. Other reference points are set to zero. The central reference point value is left without changes in a group of 2n+1 member. Reference point values of each of n pairs of reference points symmetrically arranged relative to the central reference point are scaled relative to condition Uj=U0Kj, where U0 is the central reference point amplitude, Uj is amplitude of j-th reference point pair, j=1,2,…,n is the number of each reference point pair relative to the central reference point, Kj is the scaling coefficients determined from received signal suppression condition of the first n spectral zones in spectrum. The so formed electrocardiogram signal reference point groups sequence is let pass through lower frequency filter with isoline drift signal being obtained being produced on output. The signal is amplified and subtracted from the initial electrocardiogram signal that is preliminarily delayed for lower frequency filter delay time. Device has the first lower frequency filter, discretization unit and unit for selecting anchor reference points connected in series, as well as subtraction unit, unit for saving N reference points, scaling unit, the second lower frequency filter, amplifier and delay unit. Output of the unit for selecting anchor reference points is connected to the first input of memory unit the second input of which is connected to discretization unit output. Each of N memory unit outputs is connected to one of N inputs of scaling units. Scaling unit output is connected to the second lower frequency filter input which output is connected to amplifier input. Amplifier output is connected to the first input of subtraction unit, the second output of subtraction unit is connected to delay unit output. Its input is connected to output of the first lower frequency filter. Subtraction unit output is the device output.

EFFECT: reliable removal of isoline drift.

2 cl, 8 dwg

FIELD: medicine, anesthesiology-resuscitation, traumatology, surgery.

SUBSTANCE: according to 4-point scale one should evaluate the state of 10 clinical, hemodynamic and instrumental values in patients: patient's skin by detecting its color and moisture; hemodynamic values: heart rate, systolic arterial pressure, central venous pressure, shock index; central nervous system by studying the value of Glasgow scale; respiratory system - the frequency of respiratory movements and blood saturation; cardio-vascular system - myocardial necessity in oxygen. Each value has its own point, moreover, 0 points corresponds to that fact that the index under inspection is within age standard, 1 point - when physiological parameters at rest are different against the standard, but their functions are compensated by organs of one or two systems, 2 points - compensation is kept due to alterations in more than 2 systems and it reaches its peak, 3 points correspond to adaptation failure or affected function of one or several systems, and the sum of points being 0-4 in patients one should diagnose the absence of hemorrhagic shock, at 5-9 points - the severity of hemorrhagic shock corresponds to degree I, at 10-19 points - to degree II, at 20 points and more - to degree III.

EFFECT: higher efficiency and accuracy of diagnostics.

4 ex, 1 tbl

FIELD: medicine.

SUBSTANCE: method involves recording peripheral differential upper extremity blood vessel rheogram and phonocardiogram in synchronous way. The second phonocardiogram beginning and the deepest rheogram points are detected. Pulse way propagation time reduction being found, arterial bloodstream tone growth conclusions are drawn.

EFFECT: high reliability of the results.

18 dwg, 3 tbl

FIELD: medicine; medical engineering.

SUBSTANCE: method involves recording patient electrocardiogram in maximum comfort state in one lead and photopletysmogram. Vascular tone index (VTI) is measured as time interval from next in turn R-tooth peak to the next following pulse oscillation. Set of values is built and statistically processed. Mode value MoVTIR is calculated as patient rest state characteristic to estimate current functional state of patient regulation and control systems. Electrocardiogram in maximum comfort state is recorded in one lead and photopletysmogram at the same time. A set of RR-intervals and time intervals from next in turn R-tooth peak to the next following pulse oscillation is built and statistically processed. Amo, Mo and MoVTI values are calculated to estimate current functional state of patient. Neighboring cardio-interval values are additionally measured and mean square deviation MSDP is calculated and then variational pulse ametria SAT index is calculated from formula SAT=0.1 x Mo/MSDP and integral regulation and control system stress index of patient (IRCSS)is calculated from formula IRCSS=(SAT) x [1+(Movtir-MoVTI)MoVTI. Patient organism regulation and control system state is estimated as one corresponding to normative neuropsychic stress characteristic for rest state or when working without significant psychic tension with IRCSS value being within interval from 40 to 300, working neuropsychic stress characteristic for significant tension belonging interval from 300 to 900. Neuropsychic overstress showing necessity of rest belongs to an interval from 900 to 3000. Neuropsychic overstress threatening health belongs to an interval from 3000 to 10000. Attrition showing emergency of escaping from the current state with obligatory cardiologist advice takes place when the value is greater than 10000. The device has unit for recording electrocardiogram, data processing unit and calculation unit connected to estimation unit with its output and unit for recording pulse oscillations, analog-to-digital converter unit having inputs connected to electrocardiogram-recording unit and pulse oscillations-recording unit outputs and its output are connected to calculating unit inputs via the data processing unit, and display unit for showing patient regulation and control systems state. Units for processing and calculating are manufactured on microprocessor base. Signals are form on exit from the microprocessor, their values being corresponding to integral regulation and control system stress index value of a patient(IRCSS). The unit for recording pulse oscillations is designed as electronic transducer set on patient finger. The unit for recording electrocardiogram, records cardiac pulses in single lead.

EFFECT: high accuracy in estimating functional state of human organism regulation and control system.

3 cl, 2 dwg

FIELD: medical equipment.

SUBSTANCE: device can be used in practical and sports medicine. Device has breath detector and pulse rate detector, clamp having ability of fastening to frame of glasses, joint mounted onto clamp, unit in form of clip for placing light source and photo-resistor which both are parts of pulse rate detector, and pipe. Breath thermal detector is mounted at one end of pipe. The pipe is mounted in clamp for displacement to control position of breath detector in projection of jet of breath-out air. Pulse rate detector is connected with joint through flexible wires. Wires of thermal detector are placed inside pipe. Pulse rate detector and breath detector are connected with corresponding amplifiers through joint. Output of any amplifier is connected with commutator.

EFFECT: simplified design; improved comfort for patient.

2 dwg

FIELD: medicine; cardiology.

SUBSTANCE: method allows registering differential sphygmograms by means of computer and piezoelectric transducer providing high precision. Registration is carried out continuously and doesn't take much labor input. On the base of sphygmograms by using method of finding of "coding" points, two main characteristics of heart beat rate can be found by express analysis. Two main characteristics have to be rhythm and pulse oscillations of arterial pressure induced by periodical throwing of shock volume of blood into aorta. Algorithm of data processing which is developed on purpose, provides automatic placing of "coding" (received on the base of calculation) points onto averaged graph of cardiologic cycle that provides higher precision of determination of amplitude-time parameters at any recognized normal pulsation of selected fragment of pulsogram together with additional visual correction of localization of those points. Fragment of pulsogram with duration of no less than 2 minutes (standard duration equals to 5 minutes) is used for measuring and analyzing time factors which characterize rhythm of heart beating and its variability. After that the calibration factor is calculated to transfer conditional units of computer "digitization" into common units of measurement of blood arterial pressure (in mm of mercury column) and values of pulsation increase in blood arterial pressure in mm of mercury column are determined by integrating cardiologic cycles at selected fragment of pulsogram for corresponding areas. The meanings achieved are used for calculating all the amplitude-time cardiologic hemo-dynamic factors which depend on blood arterial pressure and which characterize systole of myocardium of left ventricle and elastic-resilient properties of walls of arterial channel. Continuous monitoring of changes in amplitude-time factors of pulsogram is provided as well as practically real time scale of getting of all the computational data and quick performance of all the mathematical transformations for making spectral analysis of variability of heart beat rate and selected amplitude-time cardiologic hemo-dynamic factors to determine their total and differential spectral power of oscillations. Results of static and spectral analysis of variability of measured parameters the functional condition and character of vegetative regulation of cardio-vascular system are estimated due to comparison of measured values with average statistical numerical values of the same factors which were specified for cardio-vascular system in relation to age, sex, state of health and signs for groups of people chosen as a test group.

EFFECT: improved precision; widened number of informative factors for estimation of cardio-vascular system.

8 dwg, 2 tbl

FIELD: medical equipment; veterinary equipment.

SUBSTANCE: device is used for measurement of volumetric parameters of breathing and electrocardiogram by methods of impedance pneumography and electrocardiography. Device is intended for physiological testing under natural conditions of life and activity of patient - at work, in sports, at home as well as at checking of natural conditions of maintenance and existence of animals. Device has two generator and two signal electrodes, stable ac generator and two filters. First filter is intended for selecting cardiographic signal and the second one - for selecting respiratory signal. Stable ac generator is made with symmetrical differential output. Two T-shaped units are introduced into circuit of connection of mentioned generator with generator electrodes. Two resistors, connected in series, of first and second T-shaped unit are connected to circuit of connection of first (second) generator electrode with output of generator. Passive member (resistor or inductance) of any T-shaped unit is connected between point of connection of two resistors from the unit and case of device. Four dischargers and two resistors are additionally introduced into four-electrode device.

EFFECT: improved noise immunity for co-phase error: widened area of application.

4 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: one should determine ECG values, saturation (S), response of arterial pressure (AP) to inotropic support due to introducing dopamine (IS), microcirculation (M), central venous pressure (CVP), average arterial pressure (AvAP), hourly diuresis (D). In case of individual extrasystoles on ECG, C value being 91-90, IS being below 5 mcg kg/min, M being 2-3 sec, CVP being 4-6 cm watery column, AvAP 70 and more mm mercury column, D 30-40 ml/h each of these parameters should be evaluated as 0 points. In case of polytopic extrasystoles on ECG, at C value being 91-90 at FiO2 being below 0.5, IS 5-10 mcg kg/min, M being equal to 3-5 sec, CVP of 1-4 cm watery column, AvAP 60 and more mm mercury column, D 20-30 ml/h each of these parameters should be evaluated as 1 point. At combination of polytopic extrasystoles and myocardial ischemia on ECG, C value being 91-90 at FiO2 being above 0.5, IS above 10 mcg kg/min, M above 5 sec, CVP being below 0 or above 14 cm watery column, Av.AP 50 and more mm mercury column, D below 20 ml/h one should evaluate every value as 2 points. The values should be summarized and at total value ranged 0-6 severely affected patients should be considered as transportable people, at its value ranged 0-10 the preparation should be desired, at its value being 11 and more - it should be concluded upon nontransportability. The innovation enables to perform objective evaluation of severe state in affected patients.

EFFECT: higher accuracy of evaluation.

4 ex, 5 tbl

Up!