Method and device for applying dynamic electrostimulation

FIELD: medicine; medical engineering.

SUBSTANCE: method involves producing pulses of given frequency, modulating the pulse durations, amplifying the pulses and sending them via electrodes to biological object skin surface. Subelectrode skin area impedance capacitive component rate is determined during stimulation. Impedance rate value being close to zero, stimulation time interval is to be hold within 3-5 min and the stimulation is stopped next to it. Device has oscillator connected to pulse duration modulator, stimulus power setter connected to the second modulator input, pulse power amplifier connected to pulse duration modulator output, indication unit connected to the first output of power amplifier and electrodes connected to the second pulse power amplifier output and differentiation unit input. The device also has pulse duration shaper, memory unit, timer and adder. Differentiation unit output is connected to pulse duration shaper input. Shaper output is connected to memory unit input with one of adder inputs. Memory unit output is connected to the other adder input. The adder output is connected to timer. Timer output is connected to indication unit.

EFFECT: enhanced effectiveness and objectiveness in determining procedure duration and dose.

2 cl

 

The present invention relates to medicine and relates to transcutaneous electrical stimulation. The invention can be applied in physiotherapy and reflexology for electrical stimulation of biological objects in clinics, hospitals, rehabilitation centers, sports complexes, in veterinary medicine and in everyday life as an auxiliary or a main tool in the treatment and prevention of diseases of humans and animals.

In methods and devices for dynamic electrostimulation to determine the adequacy impacts take into account the dynamics of change in the frequency of forced oscillations of the resonant circuit formed by the inductance of the output transformer and the capacitive component of impedance subelectrode surface area of the skin. The active component of the impedance subelectrode skin affects the q of the circuit and affects the rate of damping of forced oscillations. Changing from perspiration in the process of stimulation of the capacitive component of the impedance affects the frequency of forced oscillations. The adequacy of the exposure or dose of exposure is determined by the nature of the impedance changes subelectrode skin for the optimization of therapeutic algorithm and achieve sustainable change one or more physiological parameters.

There is a method of pulse electrotherapy bio is oricheskogo object, by which the adequacy of the impact is determined by the stabilization of dynamics of change of signal amplitude (patent RU 2118901).

The method is as follows. Form of electrical pulses of a given frequency and a given duration that reinforce and serves on the electrodes for stimulation. The onset of stabilization of the amplitude of forced oscillations, the stimulation ceased.

The determination of the sufficiency of electrical stimulation and its termination in this way has no physiological justification, since the amplitude of the forced oscillations largely depends on the pressure of the electrodes on the skin surface. All this leads to less accurate dosing, and therapeutic effect because of the uncertainty of the time interval of stimulation.

Known method of psychosomatic regulation of homeostasis of a biological object, by which the adequacy of the impact is determined by the stabilization of the dynamics of changes in the duration of the first half wave signal (patent RU 2068277).

The method is as follows. Form of electrical pulses of a given frequency and a given duration that reinforce and serves on the electrodes for stimulation. Then depending on the rate of change in the first half of forced oscillations assess the effect of therapeutic stimulation, minutestotal pulse and stop the stimulation, if there is no change in the duration of the first half.

The determination of the sufficiency of stimulation used in this method has no physiological justification, because the forced oscillation frequency depends on the magnitude of the capacitive component of impedance subelectrode skin and is determined by the level of perspiration, which leads to the appearance of the salt solution with a high dielectric constant and a corresponding decrease in the frequency of forced oscillations. The time of stabilization parameter is the phase of electrodermal reactions, but is not in itself a ground for termination of procedure of the electrical stimulation.

All this leads to less accurate dosing, and therapeutic effect due to premature cessation of stimulation.

There is a method of stimulation of a biological object, by which the adequacy of the impact is determined by the level of the derivative of the output signal to change the length of the series of stimulation pulses (SU 1817335).

The method is as follows. Generate a sequence of stimulation pulses, the duration of which change with the help of the modulator is proportional to the voltage on its control input. These pulses increase and serves on the electrodes for stimulation. The energy output is directly proportional to their glutelin the STI. Pathological changes in stimulated tissues incentives at the output of the pacemaker have the form of short pulses with exponential decay and oscillatory setting process. The signal at the output of the differentiating element is sufficient to set the duration of the series of pulses is close to zero. Thus, a threshold value of the signal from the differentiating element determines the end of stimulation.

The determination of the sufficiency of stimulation used in this method has no physiological justification, because the value of the capacitive component of the impedance is determined by the level of perspiration, which leads to the appearance and concentration under electrodes salt solution with a high dielectric constant and, consequently, to an increase of the capacitive components of the impedance subelectrode plot with a subsequent decrease in frequency of forced oscillations. In addition, in the mode with a fixed electrodes for electrical stimulation of the process of lowering the frequency is always one-sided within the treatment area due to the accumulation and slow the evaporation of moisture from the skin surface. At some point saturation process perspiration, which is the termination of stimulation. The time of saturation of the phases is the th electrodermal response, but it is not in itself a ground for termination of stimulation.

All this leads to less accurate dosing, and therapeutic effect due to premature cessation of stimulation.

The known device for stimulation, taking into account the dynamics of change in impedance, contains a pulse generator connected therewith modulator and amplifier (patent RU 2068277).

A pulse voltage with a rectangular output pulse generator is fed to one input of the modulator, to another input pulses from the generator energy incentives. At the output of the modulator is formed by pulse-modulated voltage of rectangular shape, which is fed to the input of the amplifier, and its output is delivered to the biological object.

In this device, the length of the first half-wave is determined by the rectifier, which reduces the performance of the scheme. In addition, the circuit disables the stimulation as soon as you stop changing the duration of the first half, which leads to unjustified termination procedures stimulation.

A device that takes into account the dynamics of change in impedance connected in series and containing a control unit, the key unit of measurement of the amplitude (patent RU 2118901).

The control unit generates the stimulation pulses, each of which is through the key supplied to the load, and the unit of measure is of the amplitude is used to determine the stabilization parameters of skin conductance.

In this device the adequacy of stimulation is determined by the amplitude of the first half, which is largely determined by the active component of the impedance and depends on the pressure of the electrodes on the skin surface than from the capacitive component. This reduces the reliability of any estimates of the impedance for the subsequent development of therapeutic algorithm. In addition, the circuit disables the stimulation as soon as you cease, the changes of amplitude of the first half, which leads to unjustified termination procedures stimulation.

A device that implements the above method, comprising a generator of the stimulating pulses, connected to the modulator pulse duration, unit energy incentives connected to the second input of the modulator, power amplifier pulses, connected to the modulator pulse duration, the led connected to the power amplifier, the electrodes connected to the input of the differentiating element and outputs of the amplifier pulses and applied to the biological object (SU 1817335).

The generator generates a sequence of stimulation pulses, the duration of which varies modulator is proportional to the voltage on its control input. Modulated by the duration of the stimulus through the amplifier arrive at the electrodes. Energy is ihade electrostimulator is directly proportional to their duration and evaluated according to the frequency of outbreaks and the intensity of illumination of the indicator. Pathological changes in stimulated tissues incentives at the output of the pacemaker have the form of short pulses with exponential decay and oscillatory setting process. The signal at the output of the differentiating element is sufficient to set the duration of the series of pulses is close to zero. Thus, a threshold value of the signal from the differentiating element determines the end of stimulation.

Included in the circuit elements may not provide control of the rate of change of impedance and duration of stimulation. This leads to unreasonable termination procedures stimulation.

The technical result of the claimed method of stimulation and device for its implementation is to improve the accuracy of ensuring the adequacy of the impact.

The technical result is achieved in that in the method of electrical stimulation generating pulses with a specified frequency, modulate them by duration, enhance and served through electrodes on the skin surface of a biological object, according to the invention when the electrical stimulation determine the rate of change of the capacitive component of impedance subelectrode skin object and obtaining the rate of change of the impedance is close to zero withstand BP is constant interval stimulation in 3-5 minutes, after the stimulation ceased.

When determining the rate of change are known the principles converters parameters at time intervals with the memory elements to compare the previous value with the subsequent. The difference of time intervals per unit time determines the rate of change of the parameter.

It is known that the rhythmic activity of the heart is the universal operative reaction to any influence of the external environment and there is a variational method of cardiointervals, which allows to determine the level of inclusion processes control heart rhythm and reflecting the tension of regulatory mechanisms in the form of the strain index. The method is intended to record the significant and sustainable changes in functional status.

By the method of variation of cardiointervals it was found that in the interval from 3 to 5 minutes after the speed change of the capacitive component of impedance to a value close to zero, is a significant and sustainable decrease of tension of regulatory systems at the segmental level of vegetative regulation, until its stabilization. The achievement of these physiological changes can be interpreted as the minimum effective dose of electrical stimulation to produce meaningful and sustainable changes function is optional status in local or segmental effects.

The problem is solved in a device comprising a generator connected to one input of the modulator pulse duration, to the other input of which is connected the unit energy incentives, the amplifier pulses, connected to the modulator pulse duration, an indicator connected to one of the outputs of the power amplifier, and the electrodes that are connected to other outputs of the amplifier pulses and applied to the biological object and to the input of the differentiating element according to the invention additionally introduced shaper pulse duration, the memory element, the timer, the adder, and the output of the differentiating element is connected to the input of the pulse shaper, and the output of the shaper pulse duration is connected to the input of the memory element and one of the inputs of the adder, the other input of which is connected to the output of the memory element, and the output of the adder is connected to the timer, the output of which is connected to the indicator.

The use of the memory element and adder allows you to determine the rate of change of impedance and the time to stabilize its value.

Using a timer allows you to set the time interval after the stabilization of the impedance values in the process of stimulation.

Further, the invention is explained in the op is a description of specific embodiments thereof with reference to the accompanying drawings, on which:

figure 1 depicts the timing diagrams of signals;

figure 2 - structural diagram of the device.

The method of electrical stimulation of the biological object, by which the adequacy of the exposure to determine the rate of change of the impedance and the time interval for establishing the duration of a series of stimulating pulses is as follows.

Generate pulses with a specified frequency, which modulate the duration and increase, after which they are served through electrodes on the skin surface of a biological object. The adequacy of stimulation is determined by the rate of change of the capacitive component of impedance and stop stimulation after a period of time after the speed up to values close to zero. The indicator displays the rate of change of the specified parameter for stimulation and time intervals.

The presented plot "a" (figure 1) depicts the time interval of stimulation, on the plot "b" - the nature of changes in the capacitive component of impedance subelectrode skin, on the plot "C" - the time interval after the stabilization of the values of the capacitive component of impedance, on the plot "d" is a typical graph showing the change of the strain index.

At time t1on the plot "and" after the start of stimulation is reduced impedance subelectrode skin to the point the and t 2on the plot "b", in which the rate of change is close to zero, the alarm is sounded and starts counting time interval, then at the end of the time interval in 5 minutes, i.e. at time t3that signal about the end of the time interval of stimulation sufficient to decrease with stabilization of stress index, and the procedure can be terminated.

At time t2stabilization impedance plot "d" continues modify the physiological indicator as an index of stress, which, depending on the features of the nervous system in the time interval from t1to t2may be reduced or may be increased. After two or three minutes from the time of stabilization of the rate of change of t2capacitive component begins a steady decline, with a gradual plateau, continuing for a long time. Thus, it is possible to determine the minimum effective dosage. Further stimulation does not affect the index value of tension of regulatory systems, and it can be terminated.

A device for electrical stimulation (figure 2) comprises a generator 1 connected to the input 2 of the modulator 3 pulse duration, input 4 which is connected unit 5 energy incentives. To the output of the modulator 3 is connected to the amplifier 6 of the power pulses, the output 7 which is connected Indyk is tor 8, and to the outputs 9 which is connected to the electrodes 10 connected also to the input of a differentiating element 11, in addition, the device includes a driver 12 pulse duration, which is connected to the output of the differentiating element 11, the memory element 13, a timer 14, an adder 15, and the output of driver 12 is connected to the input of the memory element 13 and to the input 16 of the adder 15, the other input 17 which is connected to the output of the memory element 13. The output of the adder 15 is connected to the timer 14 is connected to the indicator 8.

The second output of the timer 14 may be connected to the input unit 5 energy incentives.

Generator 1, the modulator 3, unit 5, an amplifier 6, a differentiating element 11, the imaging unit 12 pulses, the memory element 13, the adder 15, the timer 14 is made by the well-known schemes, described in "the Art circuitry" Horowitz, Whill. In two volumes. "World" (Moscow) and 1984, and can be made on the basis of the series C, 1561 or microcontrollers Intel, Atmel.

The electrostimulation device operates as follows.

The rectangular pulse generator 1 serves to input 2 of the modulator 3, the entrance of which 4 are connected unit 5 energy, the output of which is fed to the modulator 3 pulse duration. From the output of the modulator 3, the signals are fed to the input of the amplifier 6, the amplified pulses are fed to the electrodes 10 and to the input of a differentiating e is ment 11. From the output 7 of the amplifier 6, the signal is fed to the indicator 8, which displays the current state of stimulation parameters such as frequency, power, time intervals, the rate of change of impedance. From the output of the differentiating element 11 to the input of the shaper 12 pulse duration signals with an interval equal to half of the first period of forced oscillations. Thus, the lower the frequency of forced oscillations, the duration at the output of the shaper 12 more. The output of the pulse shaper 12 are received at the memory element 13 and to the input 16 of the adder 15 to 17 which receives the output pulses of the memory element 13. There is a comparison of the current pulse with the previous one. As soon as the difference in the duration of these periods will be close to zero, which corresponds to a decrease in the rate of change of the capacitive component of impedance to values close to zero, the output of the adder 15 will receive a signal that starts the timer 14 for counting a time interval of stimulation, during which there is a decrease and stabilization of stress index, displaying it on the display 8.

The second output of the timer 14 may be connected to the input unit 5 energy incentives for automatic cessation of stimulation at the end of the time interval for the reduction and stabilization of the strain index.

About the Eden monitor the treatment of patients with different pathologies: osteochondrosis of spine with neurologic phenomena, injuries of the lower leg and ankle joints, neurocirculatory dystonia, headache on the background of a cervical osteochondrosis.

Treatment consisted of 5-10 sessions once daily procedures, the duration of which ranged from 5 to 10 minutes. Current was supplied to the feeling painless vibration, tingling. Time plateau impedance ranged from 15 seconds to several minutes.

The use of control speakers impedance changes with exposure time interval allowed reasonable to determine the procedures and dosage. All patients well tolerated by electrical effects, unwanted side reactions were observed.

1. The method of electrical stimulation, namely, that generate pulses with a specified frequency, modulate them by duration, enhance and served through electrodes on the skin surface of a biological object, wherein when the electrical stimulation determine the rate of change of the capacitive component of impedance subelectrode skin object and obtaining the rate of change of impedance close to zero, can withstand the time interval of stimulation within 3-5 min after the stimulation ceased.

2. Device for electrostimulation comprising a generator connected to one input of the modulator pulses on the permanent the particular to the other input of which is connected the unit energy incentives, the amplifier pulses, connected to the modulator pulse duration, an indicator connected to one of the outputs of the power amplifier, and the electrodes that are connected to other outputs of the amplifier pulses applied to the biological object and connected to the input of the differentiating element, characterized in that it additionally introduced shaper pulse duration, the memory element, the timer, the adder, and the output of the differentiating element is connected to the input of the shaper pulse duration, the output of which is connected to the input of the memory element and one of the inputs of the adder, to another input of which is connected to the output of the memory element, and the output of the adder is connected to the timer, the output of which is connected to the indicator.



 

Same patents:

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Electrode device // 2252793

FIELD: medical equipment.

SUBSTANCE: device can be used in multichannel in electrical neuron-adaptive stimulators. Electrode device has joint for connecting multichannel neuron-adaptive stimulator and flat multiwired flexible cable. Each wire of cable is connected with corresponding contact of joint for switching stimulator in. Mounting shoes provided with fixing bushings are installed along the whole length of flexible cable. Electrodes are inserted into fixing bushings. Each contact of mounting shoe is connected with corresponding contact of joint via wire of flat multiwired flexible cable. Fixing metal bushing is connected contact of mounting shoe through conductor. Connection is made in such a way that number of contact corresponds to number of mounting shoe, to number of wire of multiwired flexible cable and to number of contact of joint.

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FIELD: medicine, therapy, cardiology.

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EFFECT: higher efficiency of therapy.

2 cl, 2 ex, 4 tbl

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