Electrostimulator of gastruenteric tract

FIELD: biomedical engineering, in particular, electrostimulating devices for treatment of organs and tissues, in particular, self-contained electrostimulator of gastroenteric tract.

SUBSTANCE: the electrostimulator of the gastroenteric tract has a casing formed by two insulated from each other electrodes and a dielectric housing. A generator of stimulating pulses and a power source are installed in the casing. The generator of stimulating pulses is connected to the input of the information unit of voltage restriction and to the impedance measurement unit. The output of the impedance measurement unit via an amplifier is connected to the input by step unit of voltage restriction. The output of the voltage restriction unit is connected to the electrodes. The electrodes at the same time serve as measurement electrodes of the impedance measurement unit. The second output of the generator of stimulating pulses is connected to the drop input of the voltage restriction unit.

EFFECT: enhanced efficiency of electropulse action and enhanced service life.

3 dwg

 

The present invention relates to the field of biomedical engineering, more precisely, electro-stimulation devices for the diagnosis and treatment of organs and tissues, and more specifically, to the improvement of the Autonomous electrostimulator of gastrointestinal tract (GIT).

Known electrostimulator of gastrointestinal tract, comprising a housing formed by two insulated from each other by the electrodes and the dielectric sleeve into which you installed the generator of the stimulating pulses and the power source for it [A.S. No. 936931 the USSR, MCI And 61 N 1/36 / Electrostimulator of gastrointestinal tract / Baker VV, Agafonnikov V.F., Dambai GC, Kobozev VI and O.S. Popov - Publ. 23.06.82, bull. No. 23].

This should be taken as a prototype.

Lack of pacemaker prototype is the following. It is known that the current threshold of excitability of various GI is different. So Ski and Avisit [A.A. Vishnevsky, ALEXANDER Livshits, Vilani BTW electrical Stimulation of the gastrointestinal tract. - M.: Medicine, 1978. - 184 S.] believe that this current must be within 2-15 mA. In this range fall and data RTV [Oreshenkov MM electrical Stimulation of the gastrointestinal tract and its application in postoperative paresis in patients with rectal cancer: author. dis... Kida. the honey. Sciences: 14.00.27. - M., 1969. - 29 S.], to the which studied the influence of various parameters of the electric current on the motor activity of the intestine and have determined the optimal current for various departments. The minimum threshold excitability of the cardiac part of the stomach was 6.7 mA, fundic part - 4,2 mA, pyloric part is 3.5 mA. Most low threshold of excitability has duodenum, that is, the exit area of the bile and pancreatic ducts and several distal them for 2-3 see In these plots the average current corresponded to 3.2 mA. The highest threshold of excitability has colon. So when irritation of the sigmoid colon was required current up to 15 mA.

It is also known [Halperin, S. the Physiology of humans and animals. - M.: Higher school, 1970. - 656 S.], when an excessively large force of irritation the force of contraction of the muscle is sharply reduced or muscle is not reduced.

The generator of the stimulating pulses of the pacemaker prototype produces electrical pulses with a constant (and maximum) amplitude, which leads, on the one hand, to a considerable decrease in the effectiveness of electrical stimulation [Halperin, S. the Physiology of humans and animals. - M.: Higher school, 1970. - 656 C.], and on the other - to the rapid expenditure of energy used in the pacemaker power source, i.e. ultimately, reduce the service life of the pacemaker.

The present invention is the creation of a pacemaker with improved efficiency electrical impulse is CSO impacts and the increased resource of his work.

This task is achieved by the fact that in the electrostimulator of gastrointestinal tract, comprising a housing formed by two insulated from each other by the electrodes and the dielectric sleeve into which you installed the generator of the stimulating pulses and the power supply for it, the generator of the stimulating pulses is connected to the input information block limit voltage and the unit of measurement of the impedance, the output of which through the amplifier is connected to the clock input unit limit voltage, the output of which is connected to the electrodes, which is also the measuring electrodes of the unit of measurement of the impedance, and the second generator output stimulating pulses is connected to the reset input of the block voltage limitation.

The use of low-frequency signal generator stimulation pulses as a measurement is due to the fact that the electrical impedance of the tissues of the gastrointestinal tract is dependent on the degree of contraction of the muscles of the intestine, and the low frequency current (hundreds of Hertz - unit kHz) passes predominantly through the intercellular spaces and the resistance of this current will be determined by the size of meiklejohnian [Khachatryan A.P. Clinical and pathophysiological aspects of electroimpedance: dis... Doc. the honey. Sciences: 14.00.16, 14.00.27. - Tomsk, 1992. - 52 S.]. While reducing the size of meiklejohnian decrease with rotisserie growing. Receiving an electrical signal proportional to this change, you can use it to control unit voltage limitation.

The invention is illustrated by drawings:

figure 1 - block diagram of the pacemaker;

figure 2 is a schematic block voltage limitation (one of the variants);

figure 3 is a Typical plot of stress stimulating series of pulses and control signals.

The generator output stimulating pulses - 1 is connected to input information - D0 (see figure 2) block voltage limitation - 2, and with the unit of impedance is 3, the output of which is connected to the input of the amplifier 4. The output of amplifier 4 is connected to the clock input C1 (see figure 2) block voltage limitation - 2, the output of which is connected to the electrodes of the pacemaker - 5 and 6. The second output is "Wih" generator stimulation pulses - 1 is connected to the reset input - R1 (see figure 2) block voltage limitation - 2. Power supply 7 is connected with all the blocks.

Does the electrostimulator as follows.

When hit electrostimulator in a conductive environment of the gastrointestinal tract, the generator of the stimulating pulses - 1 begins to generate a series of stimulating pulses of maximum amplitude - VCT1(see figa). According to [O.S. Popov Autonomous electric tis ulacia gastrointestinal tract surgery: dis... Kida. the honey. Sciences. - Tomsk. - 1988. - 242 S.] current amplitude is 8-12 mA, MEM [Oreshenkov MM electrical Stimulation of the gastrointestinal tract and its application in postoperative paresis in patients with rectal cancer: author. dis.... Kida. the honey. Sciences: 14.00.27. - M., 1969. - 29 S.] believes that the current pulse can be up to 15 mA. Simultaneously with the generator of the stimulating pulses - 1 turns on the unit of measurement of the impedance - 3 and are measured impedance of the tissue of the intestine in the location of the pacemaker on the generator frequency stimulation pulses - 1. The amplitude of the measuring signal, so as not to cause stimulation of tissue is significantly smaller (by more than 2 orders of magnitude) the amplitude of the stimulating signal (Circuit decision block impedance measurement the amplitude of the signal from the generator stimulation pulses - 1 can be reduced in any number of times, for example, to limit the amplitude of the measuring signal in the normal resistor). The measuring electrode of the measuring unit of the impedance - 3 serve as the electrodes of the pacemaker - 5 and 6. At the same time, the signal generator output stimulating pulses - 1 is fed to the input information - D0 (see figure 2) block voltage limitation - 2, forming a series of pulses with linearly increasing amplitude - VST2(see figb) at the output of the electronic key on the transistor T1(see figure 2), which is supplied to the electrodes 5, 6 of the pacemaker. Upon reaching values of momentum in this series, the magnitude of the excitation threshold of the intestines, is the reduction of the unit of measurement of the impedance - 3 registers the surge of increased resistance (when the muscle contraction in the gut in the location of the electrodes (between them) appear deep banners [human Physiology, 4 T. - M.: Mir, 1986, vol. 4. The metabolism. The digestion. The allocation. Endocrine regulation. - 312 S.]. The distance between the intercellular spaces of the muscles of the intestine is reduced, and the resistance increases). From block - 3 signal is supplied to the booster unit - 4, which also forms a signal - VPack(see figv) for unit control voltage limitation - 2. This signal is applied to the clock input C1 (see figure 2) block voltage limitation - 2, and prevents further formation of stimulating pulses - VCT3(see Figg). While the input of the reset - R1 (see figure 2) block voltage limitation - 2 no signal from the second output - "Wih" generator stimulating pulse - 1. In the end the formation of a series of stimulating pulses - VCT1(see figa) generator output stimulating pulses - 1, on the second output - "Wih" generator stimulation pulses - 1 receive signal - VABOUT(see Figg) permanent the activities equal to the duration of the pause between each series of stimulation pulses generator output stimulating pulses - 1. The block voltage limitation - 2 goes into a stage of readiness the formation of a new series of stimulating pulses with linearly increasing amplitude with the advent of the generator output stimulating pulses is 1 of the next series of stimulating pulses (see figb). The intestinal electrical stimulation is responsible peristaltic wave, which promotes the pacemaker in the distal intestine and the process is repeated.

Figure 2 presents an example of an electrical circuit block voltage limitation.

Block circuit limits the voltage is (2) of the D-flip-flop, a four-digit binary counter, resistive matrix R-2R [Vnimanie, Onipede, Aieriseasca Chips and their application. - M.: Radio and communication. - 1989. - 240 S.] and electronic key. The scheme collected on the base of the series CR.

Here the T - chip KR1533TM2, ARTICLE - chip CR IE, R1 reset input; C1 - input clock; D1 input; S1 is the input set; D0 - input information; an R-2R resistors resistive matrix; Q0-Q3 outputs first to fourth digit counter; 0V, U - findings on nutrition; Rb- limiting resistor to the base current of the transistor VT1, performing the role of an electronic key. Work is principialnoy schemes considered in the operation of the pacemaker.

You can use digital-to-analog Converter (e.g., CPA [Vnimanie, Onipede, Aieriseasca Chips and their application. - M.: Radio and communication. - 1989. - 240 S.] instead of a resistive matrix R-2R. On the one hand, simplifies the technology of manufacturing unit voltage limitation (including, and in the accuracy of selection of resistors in the matrix), and, on the other hand, allows you to make the block limit voltage fully integrated execution.

Generator stimulation pulses can be implemented on the chip IA [CLGA THAT. Chip AND A. - 1991. - 22 S.] using as the second generator output stimulating pulses 13 to the output schema.

Thus, the introduction of the electrostimulator of gastrointestinal tract new distinctive features have enabled us to achieve a new positive result - increase therapeutic effect and increase the service life of the pacemaker.

The electrostimulator of gastrointestinal tract, comprising a housing formed by two insulated from each other by the electrodes and the dielectric sleeve into which you installed the generator of the stimulating pulses and the power source for it, characterized in that the generator of the stimulating pulses is connected to the input information block limit voltage and the measuring unit of the pulse is ANSA, exit through which the amplifier is connected to the clock input unit limit voltage, the output of which is connected to the electrodes, which is also the measuring electrodes of the unit of measurement of the impedance, and the second generator output stimulating pulses is connected to the reset input of the block voltage limitation.



 

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FIELD: medicine, in particular, electrostimulating devices for treatment of organs and tissues.

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Electrode device // 2252793

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