Differential diagnosis method for distinguishing compensated and decompensated chronic tonsillitis form
SUBSTANCE: method involves carrying out infrared saliva spectroscopy and determining mean values of infrared radiation pass band in frequency ranges of 3085-2832 cm-1, 2120-1880 cm-1, 1600-1535 cm-1, 1543-1425 cm-1, 1430-1210 cm-1, 1127-1057 cm-1. Mean value in the range of 1600-1535 cm-1 being greater than 35.9, in the range of 1543-1425 cm-1 being greater than 57.9, in the range of 1430-1210 cm-1 being greater than 54.5, compensated chronic tonsillitis is considered to be the case. The mean value in the range of 1600-1535 cm-1 being less than 32.5, in the range of 1543-1425 cm-1 being less than 65.2, compensated chronic tonsillitis is to be diagnosed. The mean value in the range of 1600-1535 cm-1 being less than 35.9, in the range of 3085-2832 cm-1 being greater than 72.8, compensated chronic tonsillitis is to be diagnosed. The mean value in the range of 1600-1535 cm-1 being less than 35.9, in the range of 1127-1057 cm-1 being greater than 51.7, compensated chronic tonsillitis is to be diagnosed. The mean value in the range of 1600-1535 cm-1 being less than 35.9, in the range of 2120-1880 cm-1 being greater than 79.7, compensated chronic tonsillitis is to be diagnosed. The mean value in the range of 1600-1535 cm-1 being less than 35.9, in the range of 2120-1880 cm-1 being less than 79.7, decompensated chronic tonsillitis is to be diagnosed.
EFFECT: high reliability and simplicity of differential diagnosis.
The invention relates to medicine, namely to otorhinolaryngology.
The problem of chronic tonsillitis is most relevant in otorhinolaryngology not only its prevalence is 15% of the total population and 22.1-40.1 per cent among children, but the absence of objective criteria for the diagnosis of compensated form with immunological compensated and decompensated forms of chronic tonsillitis with immune decompensation, which positively addressed the issue of surgery - tonsillectomy.
The state of immunological activity of lymphoid tissue of the tonsils is not always the same as established by clinical signs diagnosis of compensated or decompensated forms of chronic tonsillitis. Used for the clinical diagnosis of chronic tonsillitis criteria (size, presence of adhesions, scars, septic traffic indication of Giza, Zack, Transfiguration, submandibular lymphadenitis and others) are not associated with immunological function of the tonsils and can't testify about compensation or decompensation.
A prototype of the proposed method, the authors propose a laboratory method of diagnostics of the immunological activity of the tissue of the tonsils by determining the average number of cells of the lymphoid series (small lymphocytes and lymphocytes in stage blast is transformatsii) contents of the mouths of the crypts of the tonsils in one big square camera Goryaeva by counting cells in 10 boxes (5 in the top and bottom rows of the grid) using prednisolone samples which increases the migration of the formed elements of the tissue of the tonsils on the surface, the openings of the gaps and crypts; what characterizes the functional activity of the tonsils. Prednisolone stimulates formation in cells regulatory peptide-vasocardin, which blocks the enzyme hyaluronidase, resulting in enhanced barrier function of the blood-tissue interfaces barriers, in particular the permeability of the capillary bed. In patients with compensated chronic tonsillitis at the baseline lymphocyte count 73±4 after taking prednisone - increase to 207±10, an increase in the migration of lymphocytes into the lumen of the crypt to 304±8% (p<0,01).
In patients with decompensated chronic tonsillitis without comorbidity to prednisone the number of lymphocytes 5±1, then 6±1; increasing migration of lymphocytes into the lumen of the crypt to 117±5% (p<0,05). In healthy individuals initial number of cells of the lymphoid series in the contents of the crypt 22±2, after administration of prednisolone -38±3, increasing the migration of lymphocytes into the lumen of the crypt - 187±6% (p<0,05).
When decompensation of the functions of the tonsils number of cells of the lymphoid series in the lumen of the crypts significantly reduced compared with patients with compensated chronic tonsillitis - more than 12 times and with a healthy - 4 times, what evidence is em about the absence of any functional reserve in the tonsils (Blackie AV, Vikulov CENTURIES, Bolotov PN. Morphofunctional state of the tonsils. J. Russian otolaryngology". 2004. - №2 (9). - P.114-116).
In the opinion of the authors, the method has some disadvantages - difficulty in holding him and interpretation, and hence a low degree of reliability.
The authors propose a method of differential diagnosis of compensated and decompensated forms of chronic tonsillitis research saliva using infrared spectroscopy. Infrared spectroscopy was carried out using an infrared analyzer "ICARUS" on 9 channels for 1 min, after 1 sec. As the study material was used saliva in an amount of 5 ml Were examined 56 people, including 22 patients with compensated chronic tonsillitis, 24 patients with decompensated chronic tonsillitis and a control group of healthy individuals -10 people.
The most informative was 1, 2, 3, 4, 5, 6 the channels corresponding to the ranges 3085-2832 cm-1, 2120-1880 cm-1,1600-1535 cm-1, 1543-1425 cm-1, 1430-1210 cm-1and 1127-1057 cm-1, which was determined average values of the transmittance of infrared radiation.
The sample of the saliva of the patient for 30 seconds in each range was performed 10 cycles of measurement of the rate of transmission of infrared radiation. Thus was SF is milovana learning multidimensional sampling with 6 variables (ranges) and volume (rows) 560, where each row had the label of one of the States: compensated chronic tonsillitis, asthma chronic tonsillitis and control. The sample was analyzed PC method hierarchical decision trees (classification trees). / Potemkin VG MATLAB 6: a design environment for engineering applications. - M.: DIALOG-MIFI, 2003. - 448 S./.
Algorithm " decision trees" is a sequential hierarchical structure consisting of nodes, which contain the rules, i.e. the logical structure of the form " If...then". The leaf nodes of the tree are the leaves, corresponding to the found solutions and brings together a number of rows (States) of the training sample.
The aim of building a " decision tree" is revealing in the training set meaningful patterns or systematic relationships between indicators infrared transmittance values (dimensionless) and the conditions of the patient, which can then be applied to new measurements, the samples of saliva, thus diagnosing the patient's condition. This method combines effective analytical apparatus generating solutions with ease of use and intuitive and easily interpretable outcomes.
The method of decision trees allows to predict the membership of a sample of saliva specific patients the NTA to one of its States: compensated chronic tonsillitis, decompensated chronic tonsillitis and the absence (control). As a result of this procedure produced the decision rules:
According to these rules for a successful forecast is 99,3%.
Based on these data the authors concluded that when the value of the average transmittance of infrared radiation in the 3 range more 35,9, 4 range more 57,9, and in the range of less than 5 54,5 - diagnosed chronic tonsillitis, compensated form; when the value of the average transmittance in the 3 range over 32.5 - diagnosed chronic tonsillitis, asthma form; if the average transmittance in the range of less than 3 32,5 and 4 range less 65,2 - diagnosed chronic tonsillitis, compensated form; if the average transmittance in the range of less than 3 35,9 and 1 range more 72,8 - diagnosed chronic tonsillitis, compensated form; if the average transmittance in the range of less than 3 35,9 and 6 more range of 51.7 - diagnosed chronic tonsillitis, compensated form; if the average transmittance in the range of less than 3 35,9 and 2 more range 79,7 - diagnosed chronic tonsillitis, compensated form; the ri value of the average transmittance in the range of less than 3 35,9, and in 2 the range of less than 79,7 - diagnosed chronic tonsillitis, asthma shape. This is used by the authors for the differential diagnosis of compensated and decompensated forms of chronic tonsillitis in patients with clinically diagnosed chronic tonsillitis.
In addition, the proposed method for the diagnosis of chronic tonsillitis according to a study in the saliva of the patient by the method of infrared spectroscopy, painless, quick, and can be performed on an outpatient basis.
Patient G., survey map No. 29 preliminary clinical diagnosis of compensated chronic tonsillitis (complaints of sore throat, sore, feeling of a foreign body, breath; a history of frequent sore throats (1 per year); tonsil 2 degrees, hilly, wide gaps, introducing tube, adhesions with nebnymi fit the symptoms of Giza, Zack and Transfiguration). The study of saliva using an analyzer "ICARUS". The average transmittance of infrared radiation were: 1 range 73,8; 2 range 68,3; 3 range 38,4; 4 range 59,1; 5 range 56,3; 6 range 54,6. Turning to the method of "decision trees", which are represented graphically in the text above. Always start with the 3 main range, which our patient 38.4; look in the "decision tree" - which then corresponds to the 3 range < =35,9 it and go to 1 range, which our patient equal 73,8 that obliges us to make a graphic image of a "decision tree". This corresponds to the "decision tree" 1 range <=72,8, and this gives us the right to confirm this patient delivered her diagnosis of chronic tonsillitis compensated form, and to recommend conservative treatment. Thus, using the logic of decision rules developed and proposed " decision tree"for us to confirm this diagnosis in specific patient enough to use the average transmittance in only two bands (3 and 1) of the 6 investigated.
Patient A., map of survey No. 31, a preliminary diagnosis of decompensated chronic tonsillitis (complaints of sore throat, scratchy, the appearance of purulent "grains" on the tongue, bad breath, weakness, malaise, low-grade fever, joint pain; a history of frequent sore throats (1 year), frequent Colds (up to 4 times per year); increase and tenderness to palpation of the submandibular lymph nodes, tonsils 2 degrees, hilly, wide gaps, introducing tube, subepithelially festering follicles, adhesions with nebnymi dochkami, symptoms of Giza, Zack and Transfiguration). The study of saliva using the apparatus analyzer "ICARUS". Show is whether the average transmittance of infrared radiation were: 1 range 71,6; 2 range of 72.6; 3 range 31,1; 4 range of 55.3; 5 range 51,8; 6 range of 50.9. Begin with the main 3 range, the average transmittance for him in our patient is equal to 31.1. Turn to our proposed "decision tree" and see that it corresponds to 3 range >35,9, and it is commanded to move 1 range, the average transmittance of which our patient equal 71,6, which corresponds to the "decision tree" 1 range >72,8 that, and this again makes us go to 6 range, the average transmittance of which our patient equal 50,9, which corresponds to the "decision tree" 6 range >51,7 that, and this again makes us go to 2 range, the average transmittance of which our patient equal to 72.6, which corresponds to the "decision tree" 2 range > 79,7 that, and this already gives us the right to confirm in this patient diagnosed with chronic decompensated tonsillitis form and recommend surgery (tonsillectomy). Thus, in this particular patient, using the logic developed decision rules using the proposed "decision tree"to confirm this diagnosis were used, the average transmittance of infrared radiation already in four ranges (3, 1, 6 and 2) of the 6 investigated.
Thus, the practical doctor, putting Kleene what if the patient is diagnosed with chronic tonsillitis and additionally examining saliva on the device-analyzer "ICARUS", with 6 ranges data average transmittance of infrared radiation, we have developed and graphically presents the scheme of a "decision tree" differentiates offset from decompensated forms of chronic tonsillitis.
The method of differential diagnosis of compensated and decompensated forms of chronic tonsillitis research saliva, characterized in that in patients with clinically diagnosed chronic tonsillitis spend infrared spectroscopy saliva, determine average values of the transmittance of infrared radiation in the range 3085-2832 cm-1, 2120-1880 cm-1, 1600-1535 cm-1, 1543-1425 cm-1, 1430-1210 cm-1, 1127-1057 cm-1and if the value of the average in the range 1600-1535 cm-1more 35,9, in the range 1543-1425 cm-1more 57.9, in the range 1430-1210 cm-1less 54,5, diagnosed with compensated chronic tonsillitis, if the value of the average transmittance in the range 1600-1535 cm-1less 32,5 and in the range 1543-1425 cm-1less 65,2, diagnosed with compensated chronic tonsillitis, if the value of the average in the range 1600-1535 cm-1less 35,9 and in the range 3085-2832 cm-1more 72,8, diagnosed with compensated chronic tonsillitis, if you meant the e average transmittance in the range 1600-1535 cm -1less 35,9 and in the range 1127-1057 cm-1more 51,7, diagnosed with compensated chronic tonsillitis, if the value of the average transmittance in the range 1600-1535 cm-1less 35,9 and in the range 2120-1880 cm-1more 79,7, diagnosed with compensated chronic tonsillitis, and if the value of the average transmittance in the range 1600-1535 cm-1less 35,9 and in the range 2120-1880 less 79,7, diagnosed with decompensated chronic tonsillitis
SUBSTANCE: method involves determining malonic aldehyde quantity in blood serum before and after treatment in addition to clinical study. The quantity growing after having applied the transcranial magnetic stimulation method more than by 15% when compared to an initial state, treatment result is estimated as positive one.
EFFECT: high estimation method objectivity level.
FIELD: medicine, therapy.
SUBSTANCE: invention relates to a method for prognosis in lingering pneumonia course in patients with liver pathology that involves assay of bilirubin-aminotransferase index (BAI). The latter is calculated as a product of two ratios: activity of alanine aminotransferase to activity of aspartate aminotransferase and the content of serum bound bilirubin to the total bilirubin. The lingering pneumonia course is diagnosed at BAI value above 1. The measurement of BAI value allows carrying out prognosis for lingering pneumonia course in patients with liver pathology that promotes to the well-timed correction of treatment and improvement of the patient living quality.
EFFECT: improved method for prognosis.
FIELD: analytical diagnostics.
SUBSTANCE: biochemical examination of blood and endoscopic ultrasonography are performed. When alkaline phosphatase activity is increased by 150% and more relative to normally occurred values, alanineaminotransferrase by 250% and morem and amylase by 150% and more, and when level of conjugated bilirubin is increased by 150% and more relative to normal level, while diameter of common bile duct is 7 mm and more, choledocholithiasis is diagnosed.
EFFECT: increased early recognition accuracy.
FIELD: medicine, hematology.
SUBSTANCE: one should detect the quantity of human CD20+ B-lymphocytes in patient's blood due to immunofluorescence assay by applying monoclonal antibodies and at the level of CD20+ cells ranged 0.4 -7.0 x 109/l one should predict nonprogressing flow of chronic lympholeukosis, and at the level of CD20+ cells being above 7.0 x 109/l - progressing flow.
EFFECT: higher efficiency of prediction.
1 dwg, 2 ex, 1 tbl
FIELD: veterinary medicine, biochemistry.
SUBSTANCE: the present innovation deals with boiling an extract, cooling, centrifuging, dissolving a residue, cooling, centrifuging, dissolving a residue, adding sulfuric acid into a tube and 1%-condensate's solution followed by heating, cooling, photometry against the control at wave length being 315 nm, as a condensate one should apply resorcinol.
EFFECT: higher accuracy and economy of detection.
2 ex, 1 tbl
SUBSTANCE: method involves fixing material and setting histochemical reaction on detecting cholinergic nerve structures. The fixed material under study is incubated during 60-90 min in thermostat at 37°C in mixture containing acetylthiocholine iodide as substrate, washed, treated with alcohols in growing concentrations, cleared and enclosed into balsam. The material is fixed with 2% glyoxylic acid prepared on 0.1 M phosphate buffer solution having pH of 7,0. Histochemical reaction is set concurrently with material fixation for detecting adrenergic nerve structures containing neuromediators forming luminescent reaction products with glyoxylic acid, in which the material is incubated during 15-20 min at temperature of 20-25°C. Then it is dried and heated during 5-10 min in thermostat at 80°C, studied with luminescent microscope, subjected to morphometric study and photographed. Then, histochemical reaction is set on the same material for detecting cholinergic nerve structures.
EFFECT: high comparison accuracy on the same portion of tissue being used.
SUBSTANCE: method involves determining proportion of cyclic adenosine monophosphate to cyclic guanosine monophosphate, serotonin and histamine level and serotonin/histamine ratio coefficient, content of prostaglandin E2 and prostaglandin F2α and adenylatecyclase index. Cyclic adenosine monophosphate to cyclic guanosine monophosphate ratio being equal to 2.7-3.3, serotonin level of 4.5-6.6, content of prostaglandin E2 being equal to 670-1340 mg/g of protein and prostaglandin F2α to 320-960 mg/g of protein, label index being equal to 10.1-35,0% and adenylatecyclase index being equal to 19.2-30.0 rmole/g of protein/min, stomach and duodenal ulcer healing is predicted.
EFFECT: high accuracy of prognosis.
FIELD: medicine, oncology.
SUBSTANCE: before carrying out hyperbaric oxygenation (HBO) one should detect the content of lipid peroxidation products in the condensate of expired air. If the content of TBC-active products is below 14 conventional units it is necessary to perform about 3-4 HBO seances at 1.3 absolute atmosphere for 40 min both in pre- and postoperative periods. If the content of TBC-active products varies 14-24 conventional units one should conduct about 3-4 HBO seances at 1.3 absolute atmosphere for 40 min in preoperational period only. If the content of TBC-active products is above 24 conventional units HBO séances should not be carried out . The method is considered to be noninvasive, of high information value and enables to increase efficiency to apply HBO in patients with pulmonary cancer planned for operative treatment.
EFFECT: higher efficiency.
FIELD: medicine, obstetrics.
SUBSTANCE: one should study placental tissue to prepare 10% homogenate and detect NADPH-oxidase activity according to reduction of 2.6-dichlorophenylindophenol at the presence of NADPH. Results of reaction should be specified spectrophotometrically at wave length being 600 nm. Method is atraumatic and enables to predict the development of encephalopathy in neonatals at high accuracy.
EFFECT: higher efficiency of prediction.
SUBSTANCE: method involves producing substrate for detecting analytes in a sample by treating the sample at least under two selectivity conditions depending on adsorbent and eluate combinations. It enables one to retain analyte with the sorbent, to make identification by applying desorbing spectrometry. Method for setting diagnosis with the substrate is given.
EFFECT: high specificity of diagnosis method.
34 cl, 33 dwg
SUBSTANCE: method involves fills questionnaire in early postoperative period according to scheme 1, doctor builds a map for estimating life quality of surgical patient in early postoperative period according to scheme 2 using the obtained data. Next to it, clinically significant changes are determined between control points on the map according to scheme 2. The changes being 5-10 points heavy, weakly expressed differences are found to be the case. The value being 10-20 points heavy, the differences are found to be of moderate severity degree. The value being greater than 20 points, the differences are found to be of marked severity in the early postoperative period.
EFFECT: high accuracy in determining general life quality dynamics.
FIELD: veterinary medicine.
SUBSTANCE: method involves separating oviduct from uterus. The oviduct is plunged into reservoir filled with liquid. Air is introduced with overpressure through oviduct infundibulum. Oviduct obstruction is estimated from air discharge rate from the uterine end and pressure drop degree.
EFFECT: high accuracy of diagnosis; simplified instruments used.
1 dwg, 1 tbl
FIELD: medicine; medical engineering.
SUBSTANCE: method involves creating electrostatic field around human body. Field intensity is to provide luminescence of cotton fabric in front of biologically active points having increased electric conductivity. Luminous sites positions are fixed relative to human body outline in dark chamber on the background of illuminated screen. The positions are compared to biologically active point pattern maps. The luminous cotton fabric areas are filmed with digital photographic apparatus or video camera. The luminous cotton fabric areas positions comparison to biologically active point pattern maps is carried out by fitting map scales and superimposing the images. Biologically active points of increased electric conductivity are determined from four sides. Device has dark chamber, electrodes, constant voltage source, unit for moving positive electrode, unit for fixing luminous cotton fabric areas and highlightable background screen. The screen is positioned at a distance from the positive electrode to have enough space for placing human body.
EFFECT: high speed in determining meridian states of biologically active points on human body.
11 cl, 1 dwg
SUBSTANCE: method involves applying chromato-mass-spetrometric techniques for determining small and large intestine bioptate fatty acids content. The number of microbial cells is determined from chromato-mass-spetrogram peak areas. The calculated proportions are interpreted for diagnosing irritated intestine syndrome.
EFFECT: high accuracy of diagnosis.
SUBSTANCE: method involves applying computer-aided processing of general plan survey X-ray films with one or several zones of interest being detected on digitalized image corresponding to the number of osteogenesis foci. Quantitative osteogenesis intensity estimate is obtained by applying test grid and interpreting ratio of areas corresponding to distraction regenerate mineralization degree. Boundaries are determined in each zone of interest for delimiting intensity ranges characterizing tissue mineralization degrees at osteogenesis stages and reference points are marked. The first reference point is selected on proximal bone fragment end turned to diastasis. Lower boundary line of the proximal test grid, composed of parallel lines being perpendicular to long bone axis, is superposed with the first reference point. The second one is selected on distal bone fragment end turned to diastasis and the upper line of the distal test grid is superposed with it. Every region belonging to a zone of interest confined by neighboring test grid lines is segmented within the scope of established boundaries into intensity ranges and intensity range area shares in the total area of each region belonging to zone of interest. The intensity range area share proportions are used for estimating osteogenesis intensity.
EFFECT: wide range of functional applications.
FIELD: medicine, stomatology.
SUBSTANCE: in patients with defects of dental rows one should conduct masticatory testing, masticatiography and registration of somatoautonomic values (arterial pressure, heart rate) simultaneously before, during and after the end of orthopedic therapy to calculate the index of adaptive effect of masticatory system that characterizes the profitable ness of masticatory system. Due to comparing the values of the index of adaptive effect of the system with average values of efficiency optimum for different types of prostheses one should evaluate the result of orthopedic therapy and adaptational body capacities to plan further rehabilitation measures. The innovation enables to obtain objective evaluation of masticatory functional activity in patients in the process of orthopedic therapy.
EFFECT: higher efficiency of evaluation.
2 ex, 2 tbl
FIELD: medicine, obstetrics.
SUBSTANCE: the present innovation deals with predicting disadaptive processes in women in dynamics of menstrual cycle. During menstrual cycle beginning since the 1st d to the 21st d one should detect the dynamics for alteration in coefficient of activity of syntoxic adaptation programs (CASAP), calculated by the following formula:
where CST - concentration of blood serotonin, AAT-III - activity of antithrombin III, Aaoa - total antioxidizing activity of plasma, CCD8 + - concentration of T-suppressors, Cad - concentration of blood adrenalin, Cα2MG - concentration of α2-macroglobulin, CMDA - concentration of malonic dialdehyde, CCD4 + - concentration of T-helpers. Moreover, normally CASAP value alters two-fold against the first day of the cycle - since 0.70 up to 1.40 on the 21st d of the cycle, at no alterations in CASAP value one should diagnose female disadaptive alterations leading to failed pregnancy. The innovation enables to perform diagnostics of disadaptive processes in women in dynamics of menstrual cycle followed by prognostic conclusion upon future pregnancy.
EFFECT: higher accuracy of diagnostics.
FIELD: medicine, oncourology.
SUBSTANCE: one should choose the number of points for biopsy : 1 point of biopsy/5 cu. cm of an organ, then it is necessary to detect the portion of cancerous parenchyma in bioptates in percentage morphometrically due to analyzing of not less than 1000 points minimum in 5 sections of preparation, the volume of cancerous parenchyma in an organ should be detected by the following formula:
where X - average value for the portion of cancerous parenchyma in an organ, in %; ΣA - the portion of cancerous parenchyma in bioptate in %; N - the number of bioptates. The present innovation enables to detect cancerous parenchyma both in case of interrupted and diffused forms of prostatic cancer.
EFFECT: higher accuracy of detection.
1 dwg, 3 ex
FIELD: medicine, pathological anatomy.
SUBSTANCE: the present innovation deals with detecting viability in neonatals of 22-27-wk-long gestation, at their body weight up to 1 kg based upon evaluation of thymic morphological maturity. Moreover, in 10 visual fields in medullary substance in thymic lobules one should calculate the content of Hassal's bodies and reticuloepithelial cells. If the content of reticuloepithelial cells is above 10 and Hassal's bodies - above 2 one should consider a neonatal to be a viable one, at the content of reticuloepithelial cells being below 9 and Hassal's bodies - below 2 - as nonviable one. This method enables to detect quantitative criteria in evaluating the viability in neonatals at extremely low body weight by thymic state for the first time, helps to increase accuracy and simplify pathologoanatomical diagnostics of viability and objectively evaluate tactics and purposefulness of resuscitation procedures.
EFFECT: higher accuracy and efficiency of evaluation.
3 ex, 1 tbl
SUBSTANCE: the present innovation deals with predicting opisthorhiatic hepatic and gastro-duodenal lesions. In the course of esophagogastroduodenoscopy one should evaluate the degree of mucosal lesion in pyloric gastric department, and, also, the presence and degree of duodenogastric reflux, in case of which one should introduce a flexible catheter into duodenal bulb through biopsy canal of a gastroduodenoscope followed by aspiration of duodenal bulb's content under visual control followed by direct microscopy of this content with the purpose to detect helminthic eggs. During sampling the content of duodenal bulb one should introduce a catheter there being at 1-1.5 cm against pyloric bagasse and up to the major duodenal papilla one should perform slipping movements above mucosal surface. Aspiration should be fulfilled into a 10-20-g-syringe for 2-3 min. The method enables to detect infection with opisthorchiasis at low intensity of opisthorchiatic invasion.
EFFECT: higher accuracy of diagnostics.
FIELD: medicine, clinical toxicology.
SUBSTANCE: at patient's hospitalization one should gather the data of clinical and laboratory values: on the type of chemical substance, patient's age, data of clinical survey and laboratory values: body temperature, the presence or absence of dysphonia, oliguria being below 30 ml/h, hemoglobinuria, erythrocytic hemolysis, exotoxic shock, glucose level in blood, fibrinogen and creatinine concentration in blood serum, general bilirubin, prothrombin index (PTI), Ph-plasma, the state of blood clotting system. The state of every sign should be evaluated in points to be then summed up and at exceeding the sum of points being above "+20" one should predict unfavorable result. At the sum of "-13" prediction should be stated upon as favorable and at "-13" up to "+20" - prediction is considered to be doubtful.
EFFECT: higher accuracy of prediction.
2 ex, 3 tbl