Device for plasma-dynamic treatment of infected wounds and cavities of human body

FIELD: medicine; infectious therapy.

SUBSTANCE: device for plasma-dynamic treatment of infected wounds and cavities has high voltage electric pulse oscillator provided with low-sized high voltage pulse electric-charge unit housed inside carrier dielectric case. The case has co-axial electrode system which has ring-shaped and rod electrodes separated by dielectric insulator. Co-axial electrode system is placed inside optical-transparent quartz member made in form of flask which has perforated semispherical working end. Co-axial system is disposed to have space relatively inner surface of carrier case of unit. Part of internal surface of the unit - at the area of semispherical working end of flask - is made of material which is able to reflect radiation of visible and UF range of spectrum. Removable outlet union, provided with branch pipe connected to union, is mounted onto working part of carrier case of unit. Branch pipe is connected with member having perforated semispherical working end at the opposite side. Opposite edge part of carrier case has support sealing bushing with inlet pipe which is connected with ozone generator conjugated with vessel for containing oxygen. Inlet pipe communicates with space to inner surface of carrier case of the unit and outer surface of flask.

EFFECT: improved efficiency of treatment; improved reliability of operation.

10 cl, 2 ex

 

The invention relates to the field of medicine and relates to methods and devices used for the prevention and treatment of wounds and wound infections, and Infectology.

Health problems more complicated. Military conflicts involving weapons of mass destruction, environmental, natural and manmade disasters, acts of terrorism lead to a sharp increase in fighting injuries and traumas, injuries peacetime, requiring, as a rule, timely surgical intervention.

Infection is the main type of postoperative complications, a significant source of lengthening the duration of treatment and the main cause of deaths after operations. Its species composition in 50-70% of cases is mixed. In pathological material can be detected as aerobic and facultative anaerobic microorganisms (Staphylococcus, Escherichia, and Pseudomonas aeruginosa, Streptococcus etc), and obligate anaerobic microorganisms (bacteroids, fusobacteria, peptococci, diphtheroids, Clostridium etc). A huge number of pathogenic microorganisms, their high ability to mutations and small time replication does not allow the human immune system time to respond to the rapid adaptability of microorganisms.

The threat of new diseases, infections and complications, there is a need for the t development of modern medical technology and treatment of appropriate technical means, enabling the implementation of the clinic highly effective, simple and affordable for the majority of people methods for the treatment of wounds and wound infections, inflammatory and infectious diseases, including dangerous diseases.

In this regard, the application of ozone technology and their modifications for prevention and treatment of diseases, allowing the achievement of high bactericidal, fungicidal, virucidal, immunocorrective, detoxifying, protivoiznosnyh, oxigenada and other effects in combination with other forms of energy is a promising direction in solving public health problems.

Known apparatus for the sterilization of the object gas, which is used as the excited atomic O and molecular oxygen O2*derived from ozone-air mixture, continuously cooling the sterilized object, with its periodic radiation quanta of light with a wavelength of 1500-3080 angstroms and energy >5,26 eV [1].

This unit contains: ozone generator in the form of the electrode system connected to an AC power source and generates the power supply to the spark discharge, producing, in turn, injected into the ozonizer compressor ambient air ozone-air mixture, continuously cooling the object of sterilization, contact camera located in it about what the target sterilization, quartz lamps (quanta of light sources with a wavelength of 1500-3080 angstroms and energy >5,26 eV.

The disadvantages of this device are:

- unreliability disinfection foci of infection, infected wounds and body cavities of a complex configuration and a large depth, and the need to use long exposures impact on them due to the presence of small amounts of excited atomic O and molecular O2* oxygen obtained by periodic exposure to light quanta ozone-air mixture having an initial low concentration of ozone produced by spark discharges;

the presence of ozone, with unreliable and inefficient (in terms of production of ozone) electrode system for generating a spark discharge in pulsing through her working gas is air, which is not optimal initial working gas to achieve the maximum possible concentration of ozone generated in the ozone generator ozone-air mixture;

- loss of use of the apparatus complicated in design and technological performance in the clinical setting when handling infected wounds located on the patient's body both locally and whole body in General due to the large size and weight of its actuator pin chamber containing quartz lamps, and is also the inability to manipulate in the area of the wound;

- inability to use when processing foci of infection openly radiating quartz lamps, not safe for the patient and the surrounding medical personnel.

The closest in technical essence and the achieved result is a device for high-voltage pulsed electrical discharge treatment of infected wounds, comprising a generator of high-voltage electric pulses (GVEI) with compact high-voltage pulse electric discharge node (Vier-host), the host dielectric housing which is placed coaxial electrode system, consisting of ring and rod electrodes separated by a dielectric insulator, and a removable optically transparent nozzle in the form of quartz washer with a Central nozzle outlet on the work of [2].

When the excitation high-voltage pulse electric discharge (VIR) in the area of the discharge gap coaxial bit system there are secondary factors: pulsed electromagnetic radiation, streams of light and UV radiation with a wavelength of 1500-6000 angstroms and energy ≫5,26 eV [3], as well as ionized ozone-air flow that pass through the transparent surface of the quartz plate and coplowe hole in it and act locally on the wound surface, helping suppress the PA is agenoy microflora and stimulate reparative regeneration at the site of infection.

However, this design of the device that implements plasmadynamics processes in the treatment of infected wounds, has the following disadvantages, which reduces the processing efficiency of foci of infection infected wounds and body cavities of a complex configuration and a large depth, and thus lengthening their treatment:

- when initiating Vier related to plasmadynamics spark discharges on the environment (near the discharge gap bit Converter), for example air, effect of high-intensity flows broadband UV radiation (from 1500 to 6000 angstroms), shock waves (pressure behind the front of 10-200 bar), and especially high-temperature plasma (T=10-60 QC) and other implementing complex photochemical, chemical and thermobaric reactions [4, 5], leading to receipt of ozone (at a wavelength of below 1900 angstroms) formed (in bit area) ozone-air mixture, and to the destruction of ozone (at a wavelength of above 1900 angstroms in terms of the critical brightness temperatures 20-40 QC). In the latter case, the spark discharge channel and near it there is a strong gas heating, causing decreased production of ozone until the termination of its synthesis [6], which makes it impossible to get much of any significant quantities of excited atomic O and molecular O 2* oxygen produced during the irradiation trace amounts of ozone in the ozone-air mixture quanta of light and UV radiation produced by spark discharges;

- as small Wier site known apparatus is intended only for remote influence on the foci of infection, it is impossible to make in the course of their processing, to an infected surface wounds and body cavities of a complex configuration and a large depth, which does not allow to increase the efficiency of their treatment;

- insufficient amount of ozone and its derivatives (excited atomic O and molecular O2* oxygen)produced small Wier site known apparatus, dramatically reduces the effectiveness of the treatment foci of infection that requires long processing times and, consequently, significantly reduces the service life of the electrode system compact Vier-node.

The objective of the invention is to increase the efficiency of treatment of infected wounds and body cavities of complex configuration and great depth in their plasmadynamics processing by increasing the number of excited atomic O* and molecular O2* oxygen in the ozone-oxygen mixture produced by small Wier site to ensure their supply to the infected surface wounds and body cavities.

Sadacharan is achieved by in the apparatus for plasmadynamics treatment of infected wounds and body cavities, comprising a generator of high-voltage electrical pulses with a compact high-voltage pulse electric discharge node, the host dielectric housing which is placed coaxial electrode system, consisting of ring and rod electrodes separated by a dielectric insulator, and a removable optically clear quartz nozzle with a Central nozzle hole on the working part, its coaxial electrode system placed inside optically transparent quartz element made in the form of a flask with a perforated hemispherical working end installed with a gap relative to the inner surface of the lifting body node portion of the inner surface of which is in the area of hemispherical working end the bulb is made from a material that reflects radiation of the visible and UV spectrum, on the working side of the bearing housing Assembly is mounted removable outlet fitting with attached pipe, coupled with the cannula having at the opposite end of the perforated hemispherical working end and at the opposite end of the bearing housing installed node supporting the sealing sleeve with an inlet fitting connected to generate the rum ozone, paired with a tank of oxygen, and reported with a gap between the inner surface of the bearing housing hub and the outer surface of the bulb.

In addition, when plasmadynamics the treatment of infected wounds located on areas of the body with the surface roughness, the cannula with a perforated hemispherical working end drawn through the Central hole of radiographical with elastic deformable substrate, and at treatment of infected wounds and body cavities of a complex configuration and a large depth, the cannula conducted through the centralizer of lattice expander-limiter.

To date unknown solutions that implement the design features of the proposed system for plasmadynamics treatment of infected wounds and body cavities of a complex configuration and a large depth with the above distinctive features.

The invention, in order to enhance the treatment of infected wounds and body cavities of a complex configuration and a large depth, based on a comprehensive and consistent use of plasma-chemical kinetics and photochemical processes, implemented the proposed design of the device for plasmadynamics treatment of infected wounds and body cavities, selectioncolor are:

- initially - generating ozone from pure medical oxygen) to produce an ozone-oxygen mixture (O3+O2);

then the simultaneous and independent generating a pulsed, high-intensity and broadband stream of light and UV radiation;

- driven pulsed, high-intensity and broadband UV radiation fotorazlozheniya received ozone from an ozone-oxygen mixture (O3+O2) at the atomic and molecular O2oxygen with reduced ozone concentrations in sonadoras gas component and the subsequent transition to an excited state: atomic O and molecular O2* oxygen;

- the formation of a highly active gas component in a complex mixture: excited atomic O* and molecular O2* oxygen + traces (O3+O2);

- impact on the infection site high-level components with distinct biochemical healing properties: highly active gas component in a complex mixture: excited atomic O and molecular O2* oxygen + traces (O3+O2), and broadband flux of high-energy UV radiation directly About*, O2*+ (O3+O2) + UV, and the solution O*, O2*+ (O3+O2)to implement a variety in the ways multi-technology treatment of infected wounds and body cavities.

1 shows a diagram of a General view and block diagram of apparatus for plasmadynamics treatment of infected wounds and cavities of the body;

figure 2 - cross section Vier-node device for plasmadynamics treatment of infected wounds and body cavities (section a-a in figure 1);

figure 3 - cross section area of the mating coaxial electrode system Vier site, quartz bulb and a lifting body Vier site (section b-B in figure 2);

figure 4 - scheme plasmadynamics processing through an intermediate medicinal solution infected wounds located on the body with surface roughness;

figure 5 - diagram plasmadynamics processing superficially situated infected wounds;

figure 6 - scheme plasmadynamics processing through an intermediate medicinal solution of infected cavity of the body complex configuration and great depth;

figure 7 - scheme plasmadynamics treatment of infected cavity of the body complex configuration and great depth;

on Fig - registrarme radiation wear running coaxial electrode system Vier-node.

Apparatus for plasmadynamics treatment of infected wounds and body cavities contains (1-3): hardware complex "WIARTON" 1, comprising an ozone generator 2 with the microcompressor (not shown)associated with CI is loadnum cylinder 3, and reducing gear (not shown), as well as a generator of high-voltage electric pulses (GVEI) 4 and the high-voltage pulse electric discharge site (Vier-site) 5.

In the proposed apparatus when used as a working gas "medical" oxygen, the microcompressor off, and oxygen through reduction gearing is served directly to the discharge electrodes of the ozone generator 2 to receive ozone from oxygen barrier discharge, and then get the source working gas is an ozone-oxygen mixture.

In the proposed apparatus (in the absence of "medical" oxygen) may also receive the original of the working gas in the form of an ozone-air mixture when pumping compressor operating gas - air (from the environment) through the discharge electrodes of the ozone generator 2 with receiving the initial working gas ozone-air mixture.

Vier-site 5 consists of a supporting dielectric housing 5.1, comprising: a coaxial electrode system 5.2, which used standard automotive spark plug (standard is issued by the industry, where production and quality control guarantee high reliability when used in the form of electric discharge element in Vier site), installed through the holder 5.3 inside optically transparent quartz element is acted upon in the form of a bulb 5.4, hemispherical working end which is equipped with drainage holes 5.5 reporting the cavity of the bulb with the external environment. The flask 5.4 installed with a clearance of 5.6 (bilateral open cavity)formed between the inner surface of the bearing housing 5.1 Vier-node 5 and the outer surface of the quartz bulb 5.4. The tapered portion of the inner surface of the bearing housing 5.1 in the hemispherical region of the working end of the flask 5.4 is made from a material that reflects radiation of the visible and UV spectrum, such as thin-walled truncated cone 5.7 stainless steel with a polished inner surface. In addition, the working part of the rotor housing 5.1 installed removable outlet fitting 5.8 with attached pipe 6 connected to the cannula 7, having at the opposite end of the perforated hemispherical working end (for uniform flow distribution obtained Vier site highly active gas component and avoid injury to tissues deep wounds or infected cavities when they are processed "blind"). On the opposite end of the lifting body 5.1 installed anchor sealing sleeve 5.9 with drainage holes 5.10 and attached thereto, an inlet fitting 5.11. To the intake fitting 5.11 attached to the pipe 8, the feed from the ozone generator 2 initial working gas(ozone-oxygen mixture), through the drainage holes 5.10, the gap of 5.6 and the centralizer 5.12 with holes 5.13 is fed to the activation 5.14. After decomposition the main part of the ozone-oxygen mixture at high level (excited) atomic O and molecular O2* oxygen, together with a residual amount of ozone-oxygen mixture (O3+O2through the pipe 6 and the cannula 7 with a perforated hemispherical working end are brought to the site of infection - wound 9 or infected cavity of the body 10. When plasmadynamics the treatment of infected wounds located on areas of the body with surface roughness, use reogranization 11 with the elastic deformable substrate, which can increase the level of intermediate solution over the wound surface, ensuring the filling of the cavity radiographical 11 intermediate solution 13 and preventing their spread in the processing of the source of infection, and when plasmadynamics the treatment of infected wounds and body cavities of a complex configuration and a large depth using lattice expander-limiter 12 which provides the extension of the cavity and the smoothing of the tissue at the site of infection for uniform supply for them and the source of infection of the intermediate solution 13 and/or the above-mentioned highly active gas component.

The device shall operate as follows (Fig.1-8). Include hardware complex "WIARTON" 1. Simultaneously incorporated in the work of the ozone generator 2, a generator of high-voltage electric pulses (GVEI) 4 and wear node 5. "Medical" oxygen from an oxygen cylinder through reduction gearing directly under pressure supplied to the discharge electrodes of the ozone generator 2, to which is supplied an alternating current of high voltage. In the interelectrode space creates an alternating field of high tension with creating conditions for the formation of a large number of free electrons, with considerable energy, leading to the destruction of part of the oxygen molecules to atoms and ions with the formation of ozone (O3and, ultimately, the source of working gas in the form of an ozone-oxygen mixture (O3+O2). Received an ozone-oxygen mixture (O3+O2) passes through the pipe 8, the inlet fitting 5.11, drainage holes 5.10 reference sealing sleeve 5.9 and forth through the gap between 5.6 inner surface of the bearing housing 5.1 and the outer surface of the quartz bulb 5.4, holes 5.13 clamp 5.12 served in the area activation 5.14 Vier-node 5. Thus, passing from the outside optically transparent quartz element bulb 5.4 Vier site 5, with working inside a coaxial electrode system 5.2 in the form of highly reliable spark ignition (n is an example, car), an ozone-oxygen mixture (O3+O2subject to the active photolysis under the influence of broadband stream of light and UV radiation with sufficient energy UV radiation in the absorption band Hartley-frequencies from 2300 to 3100 angstroms and energy ≫5,26 eV (Fig [7]), and pulsed electromagnetic radiation.

In the process of active photolysis is the main part of the ozone-oxygen mixture (O3+O2)supplied from the ozone generator, the excited atomic O and molecular O2* oxygen together with a small part of the residual amount of ozone-oxygen mixture (O3+O2), as well as trace quantities of ozone (O3)produced by spark discharge in the discharge gap electrode system 5.2 coming through the drainage holes 5.5 working end of the flask 5.4, mix in the field activation 5.14 conical part of the inner surface of the bearing housing 5.1. Here they are additionally exposed to the reflected flux of light and UV radiation from the polished surface of a truncated cone 5.7, further increasing the proportion of excited atomic O and molecular O2* oxygen and, therefore dramatically reducing the share of the residual amount of ozone-oxygen mixture (O3+O2), as well as, reducing almost to h is La trace amounts of ozone (O 3).

Excited atomic O and molecular O2* oxygen are highly active "short-lived" oxidants, or destroying any abscopal, in contact with them, the activity of practically all types of pathogenic microorganisms (aerobes, anaerobes and their associations) in a few seconds. At the same time, they are not for surfactant lung tissue of humans and animals such a powerful destructive gaseous component as ozone (O3), because immediately after interaction with the object exposure to or in free mode, moving in its normal state is About atomic* or molecular O2oxygen, without breaking the MPC environment in the processing zone of the processing of an infected wound or cavity of the body.

Further, under the pressure of a mixture of atomic O and molecular O2* oxygen and residual quantities of ozone-oxygen mixture (O3+O2), namely, O*, O2*+(O3+O2through removable outlet fitting 5.8 and attached to the pipe 6 and the cannula 7, is fed continuously to the demarcated by reogranization 11 infected wounds 9 (first phase of wound healing is the inflammatory phase and hydration, cleansing the wounds of necrotic tissue), completed intermediate with a solution of 13 (for example, distilled water or 0.9% saline) (figure 4). the ri fotometricheskoi processing superficially situated infected wounds 9 or wound, located in the second or third phase of wound healing, removable outlet fitting 5.8 with attached pipe 6 connected to the cannula 7 is cut off from the working part of the rotor housing 5.1 and processing of the source of infection is carried out by direct feeding on the wound surface and cooling the above mixture of highly active gas components and exposure to UV radiation - O*, O2*+(O3+O2)+UV without the use of radiographical 11 and the intermediate solution of 13 (Figure 5).

When plasmadynamics treatment of infected cavity of the body, located in the I phase of wound healing is the inflammatory phase and hydration, cleansing the wounds of necrotic tissue, the above mixture of highly active gas components - O*, O2*+(O3+O2through the pipe 6 and the cannula 7, serves in an extended lattice expander-limiter cavity 12 of the body 10, the filled intermediate solution 13 (for example, distilled water or 0.9% saline) (6). If plasmadynamics treatment of infected cavity of the body, located in the second or third phase of wound healing, treatment of infection is carried out by direct feeding on the wound surface and cooling the above mixture of highly active gas components - O*, O2*+(O3+O2)+UV without the use of split timing is solution of 13 (Fig.7).

After a multistep process cycle of treatment with the use plasmadynamics treatment of infected wounds or cavities of the body that are in one or another phase of wound healing, hardware complex "WIARTON" 1 disable. In this case, switch off the supply medical oxygen to discharge electrodes of the ozone generator, and then turn off the ozone generator and the generator high-voltage electric pulses (GVEI). Assign wear node (with cannula or not) from the processing site of infection, relieve reogranization from the wound surface or output grating expander-limiter from the cavity of the body, evacuating the intermediate solution from the wound or cavity, if it is used at a particular stage of processing of the source of infection and carry out control and inspection. When establishing insufficient sanitization of the wound or cavity machining, if necessary, repeat. Upon reaching reorganization of the wound or cavity further maintenance performed according to standard techniques. The number of treatment sessions foci of infection of the wound or cavity of the body with the application of the proposed hardware system "WIARTON" is determined in each case by the physician on the basis of the dynamics of reparative processes in the wound or cavity of the body with their treatment.

EXAMPLE 1. Patient D., 24 years. Dia is the LCM: postinjection abscess buttocks on the left. When viewed in the upper-outer quadrant defined inflammatory infiltrate size 4.5 x 6 cm Under local anesthesia diagnostic puncture of the abscess. The contents of the abscess is focused on bacteriological examination and Express diagnostics of the presence of anaerobic microflora. Analysis of the material showed the presence of purulent contents of a large number of AGV, indicating the presence of anaerobic infections. Under the mask anesthesia produced a wide dissection of purulent containing purulent putrid exudate, which has an unpleasant odor. Subcutaneous fat covered the infectious process.

Previously, the traditional surgical treatment of the infection, aspiration of abscess, excision of necrotic tissue followed by the conventional low-frequency ultrasonic sanitation within 1-2 minutes opened the abscess through intermediate antiseptic solution (furatsilina 1:5000). After conducting ultrasonic sanitation wounds carry out control and inspection. When establishing the failure of rehabilitation wound treatment, if necessary, repeat.

After that, intraoperatively was carried out by treatment of wounds 9, located in phase I of the wound healing process, according to the proposed method plasmadynamics processing positive RA and cavities of the body complex configurations and large depth.

For this purpose (figure 4), taking into account the large surface roughness of the part of the body, where the infected wound, used reogranization 11 with the elastic deformable substrate. Set reogranization over the source of infection, and filled his cavity and cavity wounds intermediate solution 13 (distillate). Conducted through the Central hole of radiographical cannula 7, zagubieni its perforated semi spherical the working end in the intermediate solution and brought him to the site of infection. Included hardware complex "WIARTON" 1 with simultaneous inclusion in the work: the ozone generator 2 with the oxygen capacity of the generator high-voltage electric pulses (GVEI) 4 and wear-node 5. After that, spent plasmadynamics handling infected the wound cavity filled with circulating intermediate solution by continuous barbotirovaniya a high-level flow of the gas mixture - O*, O2*+(O3+O2within 3-5 minutes depending on the volume of the wound cavity and the severity of the wound healing process. After the procedure plasmadynamics processing of a wound off hardware complex "WIARTON"stopped flow in the wound cavity flow above high-level gas mixture and circulation of intermediate solution is evacuated from the cavity of his ostad and was removed from the wound surface reogranization. The wound was trenirovki the traditional way. In the following days the treatment of wounds was performed according to the above method. On the 3rd day the wound was cleansed from necrotic tissue, granulation tissue appeared on the control chromatograms AGV missing.

In the next step, treatment of the wound (figure 5), II and III phases of wound healing, radiographical and the intermediate solution is not used. After removal of the removable outlet fitting 5.8 with attached pipe 6 and the cannula 7, the surface of the wound were processed within 1-2 minutes by high-level flow of the gas mixture - O*, O2*+(O3+O2and UV radiation. At the same time the wound was pulsed UV radiation and electromagnetic fields of the spark discharge generated by the coaxial electrode system 5.2 Vier site, close to the wound, and held to its surface through a quartz flask 5.4, drainage holes 5.5 and the hole in the conical part of the lifting body 5.1.

On the 5th day the wound made by granulation marked edge epithelialization of the wound. Imposed initially delayed sutures, which were removed on day 8. Healing by primary intention with the formation of a tender scar. Wound healing was achieved, on average, 4-5 days earlier time of healing of similar severity of RAS patients of the control group treated with known metallicity infected wounds.

EXAMPLE 2. Patient L., 20 years. Diagnosis: genital candidiasis. Treatment of disease with traditional methods for more than 6 months without a positive result.

By known methods clinical blood and urine tests, researched vaginal-cervical smears on flora and a degree of purity was performed colposcopy. The results of the research were chosen tactics of treatment and types of drugs.

The patient was laid on the examination table in Trendelenburg position, providing the angle of the axis of the vaginal cavity 70-80° relative to horizontal, to prevent leakage, in the following, fill in the vagina intermediate drug solution.

Previously, when performing each treatment was performed by standard procedure of low-frequency ultrasonic sanitation focus of infection in the vaginal cavity by scoring within 1-2 minutes of the tissues of the vagina and the vaginal part of the cervix through intermediate antiseptic solution (alternately - 3% solution of hydrogen peroxide or soda solution). After conducting ultrasonic cavity sanitation is carried out by visual inspection. When establishing the failure of rehabilitation treatment was repeated.

After that, carried out the following procedure is the first stage plasmadynamics processing Vagin the through cavity (the cavity of the body complex configurations and large depth) through an intermediate solution 13 (6).

The vagina was introduced grating expander-limiter 12, fill the vaginal cavity intermediate the medicinal solution (0.9% saline), conducted through the centralizer of the expander-limiter in the mud-filled cavity of the cannula 7 with a perforated hemispherical working end connected through a pipe 6 with wear-node 5. After that included hardware complex "WIARTON" 1 with simultaneous inclusion in the work: the ozone generator 2 with the oxygen capacity of the generator high-voltage electric pulses (GVEI) 4 and Wier site. Then spent plasmadynamics handling of infected tissues of the vagina and the vaginal part of the cervix through an intermediate solution by continuous barbotirovaniya a high-level flow of the gas mixture - O*, O2*+(O3+O2within 2-5 minutes depending on the volume of the vaginal cavity and the inflammatory process. After the procedure plasmadynamics processing of the source of infection in the vagina and the vaginal part of the cervix was off hardware complex "WIARTON", stopping the flow of the above high-level gas mixture were taken from the vaginal cavity of the cannula, were evacuated from the cavity remains of the spent drug intermediate solution and was removed from the vagina will expand the e-stop.

The following procedure for the treatment of genital candidiasis is the second stage plasmadynamics processing vaginal cavity (7), which includes the processing previously sanitized (preliminary and first stages of treatment) tissues of the vagina and the vaginal part of the cervix within 1-2 minutes (without using an intermediate solution) high-level flow of the gas mixture - O*, O2*+(O3+O2and UV radiation. To do this, the tapered portion of the bearing housing 5.1 Vier site 5 was deleted removable outlet fitting 5.8 with attached pipe 6 and the cannula 7 with the provision of simultaneous exposure to an infection thread O*, O2*+(O3+O2), as well as the flow of pulsed UV radiation and electromagnetic field of the spark discharge generated by the coaxial electrode system 5.2 Vier site, the tapered portion which fits in place of the removed previously clamp expander-limiter.

The total number of sessions for one cycle of treatment of genital candidiasis conducted with the use of the apparatus for plasmadynamics treatment of infected wounds and cavities - 8-10. In one session to be held not less than 3 procedures must include steps ultrasonic sanitation and Sanayii tissues of the vagina and the vaginal part of the cervix through an intermediate solution with its barbotirovanie the Otok highly active gas mixture About*, O2*+(O3+O2), as well as the stage aeration (without using an intermediate solution) tissues of the vagina and the vaginal part of the cervix flows of highly active gas mixture - O*, O2*+(O3+O2and UV radiation.

At the end of the treatment cycle produced the fence from the vagina and the vaginal part of the cervix smear, colposcopy was performed with the issuance of a certificate of necessity to stop or continue treatment. A positive result of the treatment, the patient's genital candidiasis achieved for 8 sessions (1 session per day)that on average 2-3 times reduces the time of treatment of patients suffering from this disease.

Clinical testing of technical solutions in the form of a prototype "Device "WIARTON for plasmadynamics treatment of infected wounds and body cavities" in the clinics of the Department of Oncology AGMA and the Department of obstetrics and gynecology Omgma in the treatment of infected wounds and body cavities in 11 patients (6 patients obstetric profile) showed the possibility of increasing the efficiency of treatment of patients in the form of reduction of terms of treatment of traumatic and surgical wounds, reduce the amount used in the treatment of expensive drugs and the drug load on the patient's body.

The claimed technical solution -"Apparatus for plasmadynamics treatment of infected wounds and body cavities can be used in different branches of clinical medicine in the treatment of inflammatory diseases, infected wounds and body cavities in General surgery, traumatology and orthopedics, otolaryngology, bronchology, gynecology, dentistry, neurosurgery, cosmetic surgery and other viral infections in Infectology, as well as in cosmetics and sports medicine.

Sources of information

1. RF patent №2040935 "sterilization Method object, class A 61 L 2/14, 1995.

2. RF patent №2080092 "Apparatus for high-voltage pulsed electrical discharge treatment of infected wounds", class A 61 B 17/00, 1997.

3. Gorozhankina GI, Pedder CENTURIES and other Research intensity wear in the UV range at EH-processing of biological systems in different modes EG-Converter.//Biomedical technology and instrumentation. Omsk, 1989. - Pp.24-34.

4. Grishin, Y.M., I.E. goats, Kutyrev MV Pulse emitting discharges in systems, gas purification and recycling of toxic organic substances.//Materials of the scientific-technical. proc. "Ecology-97". S.-Petersburg, 1997. - P.119-120.

5. Lunin V.V., Popovich BTW, Tkachenko S.N. Physical chemistry of ozone. M.: Moscow state University, 1998. - 480 S.

6. RF patent №2038289 "Electric discharge ozone generator with a non-uniform electric field", class. C 01 B 13/11, 1995.

7. Report on scientific research work "Development and implementation in the clinic technology and apparatus for electrohydraulic treatment of wounds and sterilizing surgical instruments" (final)/Scientific hands Wid. - Theme No. 347-NPU, - GOS. register. No. 01870096263. - Omsk: OMPI, 1989.

1. Apparatus for plasmadynamics treatment of infected wounds and body cavities, comprising a generator of high-voltage electrical pulses with a compact high-voltage pulse electric discharge node, the host dielectric housing which is placed coaxial electrode system, consisting of ring and rod electrodes separated by a dielectric insulator, characterized in that the coaxial electrode system placed inside optically transparent quartz element made in the form of a flask with a perforated hemispherical working end installed with a gap relative to the inner surface of the lifting body node portion of the inner surface of which is in the area of hemispherical working end of the flask is made from a material that reflects radiation of the visible and UV spectrum, working part of the lifting body node has a removable outlet fitting with attached pipe, coupled with the cannula having at the opposite end of the perforated hemispherical working end and at the opposite end of the bearing housing installed node supporting the sealing sleeve with an inlet fitting connected to the ozone generator, associated with capacity when olorado, and communicated with the gap between the inner surface of the bearing housing hub and the outer surface of the bulb.

2. The apparatus according to claim 1, characterized in that for the treatment of infected wounds located on areas of the body with the surface roughness, the cannula with a perforated hemispherical working end drawn through the Central hole of radiographical with elastic deformable substrate, and for treatment of infected wounds and body cavities of a complex configuration and a large depth of cannula conducted through the centralizer of lattice expander-limiter.



 

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2 ex

FIELD: medical equipment.

SUBSTANCE: device has illuminator, microscope provided with video channel, which has video camera for forming color image of tested part of eye and optical transfer system of image of tested part of eye to the video camera, video camera for forming fluorescent image of tested part of eye and image optical transfer system of tested part of eye to the video camera and video information representation system which has one input connected with output of color image forming video camera and the other one - with output of fluorescent image forming video camera of tested part of eye. Device also has laser, adapter which focuses laser radiation to tested part of eye. Radiation wavelength of laser belongs to spectral range of absorption of photosensitizer introduced to object of test. System for optical transferring of image of tested part of eye to video camera for forming fluorescent image of tested part of eye has filters which doesn't transmit optical radiation with wavelengths being equal or shorter than laser radiation wavelength and transmits optical radiation with wavelengths exceeding laser radiation wavelengths. Illuminator and system for optical transfer of tested part of eye to video camera for forming of tested part of eye have filters with values of transmission factors within 400-640 nm spectral range in relation to values of transmission factors at wavelengths being equal or longer then laser radiation wavelength to be no less than 103. Filter of system for optical transfer of optical image of tested part of eye to video camera for forming fluorescent image of tested part of eye has relation between values of transmission factors at spectral range of fluorescence of photosensitizer and values of transmission factors at spectral range having wavelengths exceeding values of spectral range of fluorescence of photosensitizer to be higher then 103. Homogenizing beam widening member is mounted at output of adapter for mount it at axis of beam coming out of adaptor and shift in perpendicular to axis of the beam. Method of diagnostics and photodynamic therapy of eye diseases is based upon introduction of photosensitizer to patient's organism, upon having diagnostic test by means of irradiation of tested part of eye by exciting radiation and control of distribution of fluorescence intensity along tested part of eye. As photosensitizer, the compound on the base of hydroxialuminium di-, tri- and tetra sulphophtalocianin is used. Laser wavelength is chosen within 667-672 nm spectral range. Diagnostics is carried out on the base of pattern of distribution of fluorescence intensity at spectral range of 667-672 nm at when illuminating by means of laser radiation. Then the tested part of eye is subject to therapeutic illumination with increased fluorescence intensity by means of laser radiation of the unit. Diagnostics and photodynamic therapy can be conducted during the same treatment.

EFFECT: improved efficiency of treatment; reduced risk of damage of healthy tissues of patient's eye.

11 cl, 6 dwg, 1 tbl, 3 ex

FIELD: medicine, neurology.

SUBSTANCE: one should affect with infra-red impulse laser radiation generated by a matrix out of 8-10 light diodes the projection area of affected nervous trunk and its branches at total power being 32-48 W, impulse frequency of 80-150 Hz for 8-10 min. Then one should affect the area of trophic and autonomic disorders at impulse frequency being 300-600 Hz for 8-10 min. Then, without any time interval, one should affect with impulse ultrasound the projection of cervical or lumbar spinal thickening which segmentally corresponds to a traumatized limb, and the projection of nervous trunk at impulse duration of 10 msec, impact intensity of 0.4-1.0 W/sq. cm and duration of 10-12 min. procedures should be performed daily, about 10-12 procedures/course. The method enables to accelerate the process of axone regeneration and remyelinization in affected nerves, provides quicker regress of motor disorders and sensitive disorders and enables to interrupt pain syndrome.

EFFECT: higher efficiency of therapy.

2 ex

FIELD: medicine.

SUBSTANCE: invention relates to method of curing intracavitary infections, particularly, abscesses, and to devices for intracativary draining and irradiation of infection focus. Proposed method includes determination of spectrum of microorganisms in population in cavity, sizing of main infecting microorganisms in population, selection of wavelength of ultraviolet light, draining of caving and irradiation of cavity with ultraviolet light. Wavelength is chosen to provide radiation letal for infectious microorganisms. Device contains catheter with fiber optical waveguide to carry ultraviolet light, solid-state pulsing laser and drain system.

EFFECT: reduced risk of damaging of surrounding tissues.

7 cl, 3 tbl

FIELD: medicine, ophthalmology.

SUBSTANCE: trabecular area should be affected with radiation of YAG-laser apparatus at doubled frequency that generates impulses of 10+2 nsec duration. Radiation energy of a single impulse is not less than 4.5 mJ, wave length being 532 nm, spot's diameter is not less than 50 micron, frequency of doubled impulse corresponds to 1 Hz. The method enables to selectively affect trabecular area, decrease total impact dosages upon tissue.

EFFECT: decreased number of post-operational complications.

3 ex

FIELD: physiotherapy and health resort treatment.

SUBSTANCE: method envisages drinking mineral water, performing intragastric electrophoresis with mineral water, magnet-laser therapy, massage, and baths. Additionally, 2-3 days before physiotherapy and during physiotherapy, biologically active additive "succinic acid" is administered in daily dose 3 x 0.5 g after meal. Intragastric and magnet-laser therapy are performed every day consecutively without interval between them. Treatment course consists of 8-10 procedures. Method allows achieving stable remission in case of indicated diseases thanks to integrated positive effect produced on inflammatory process, velocity of epithelization of ulcerous and erosive defects, acid-forming, neutralizing, and motor functions in gastroduodenal region on the whole.

EFFECT: enhanced treatment efficiency.

5 tbl, 2 ex

FIELD: medicine, clinical oncology.

SUBSTANCE: one should perform blood exfusion at the quantity of 500-550 ml. Removed blood volume should be compensated with crystalloids at the ratio of 1:1.2 - 1: 1.3. Erythrocytic mass should be supplemented with 5-10 ml "Essentiale" solution. This mass should be introduced for a patient at simultaneous ultraviolet blood irradiation for 20-30 min. Plasmapheresis in combination with ultraviolet blood irradiation should be carried out every other day, about 2-4 seances/course, totally. The method provides normalized level of blood leukocytes and body detoxication, it, also, excludes prophylactic course of antibioticotherapy that enables to continue terms of therapy and not to decrease the dosages of chemoradiation therapy.

EFFECT: higher efficiency of therapy.

1 ex, 2 tbl

FIELD: medical engineering.

SUBSTANCE: method involves exposing an intraocular neoplasm after vitrectomy and retinotomy, smoothening retina with perfluororganic compound later substituted with silicon oil. After having removed the neoplasm, intravenous 10% Perfluorane emulsion transfusion is carried out at a rate of 60 drops per 1 min in the amount of 80-100 ml. Next to it, photosensitizer is intravenously drop-by-drop introduced into cubital vein of the same arm. Laser irradiation of blood is carried out with power of 20-50 mW through laser light guide set in advance into cubital vein of the other arm in 5-15 min after starting introducing Perfluorane. When applying 0.1-1% water solution of Khlorine as photosensitizer at a dose of 0.2-0.5 mg/kg, irradiation is carried out at wavelength of 630-633 nm during 10-45 min. The treatment is administered twice with 5 days long pause.

EFFECT: enhanced effectiveness of treatment; reduced risk of tumor cells dissemination and metastases formation.

3 cl

FIELD: medicine, endocrinology, physiotherapy.

SUBSTANCE: the present innovation deals with introducing preparations of antioxidant, antiaggregate, antithrombotic and hypolipoedemic action as detralex and sulodexide along with the impact of low-intensity laser radiation (LILR) (at wave length of 0.97 mcm and power of 5-7 W). Moreover, LILR impact should be performed by contact since the 1st d of conservative therapy on projection of the main vessels of lower limbs in, at least, 2 o\points at every of them per 1-2 min/every point, and high-intensity laser radiation (HILR) impact should be carried out by contact-free technique from the distance of 1-3 cm for visually altered part of affected limb's skin in area of trophic disorders up to the border with intact tissue, beginning from toes towards talocrural joint and longitudinally towards knee joint, proximally up to the lower third of femur.

EFFECT: higher efficiency of therapy and decreased traumatism.

1 cl, 2 ex

FIELD: physiotherapy and health resort treatment.

SUBSTANCE: method envisages drinking mineral water, performing intragastric electrophoresis with mineral water, magnet-laser therapy, massage, and baths. Additionally, 2-3 days before physiotherapy and during physiotherapy, biologically active additive "succinic acid" is administered in daily dose 3 x 0.5 g after meal. Intragastric and magnet-laser therapy are performed every day consecutively without interval between them. Treatment course consists of 8-10 procedures. Method allows achieving stable remission in case of indicated diseases thanks to integrated positive effect produced on inflammatory process, velocity of epithelization of ulcerous and erosive defects, acid-forming, neutralizing, and motor functions in gastroduodenal region on the whole.

EFFECT: enhanced treatment efficiency.

5 tbl, 2 ex

FIELD: medicine, endocrinology.

SUBSTANCE: at the background of applying microdosages of iodine and/or levothyroxine one should conduct electrophoresis with 3%-sodium thiosulfate solution. The latter should be introduced with the help of a cathode placed onto thyroid area, an anode - onto interscapular area. The area of the interlayer corresponds to 5 x 10 cm at current power being 4-8 mA, exposure time being 15-20 min. Seances should be performed either daily or every other day, about 10-12 procedures/course.

EFFECT: higher efficiency of therapy.

3 ex

FIELD: medical engineering.

SUBSTANCE: device has reservoir, containing medicament, with electrode fixed therein. The device is to be held with patient hand. Eye-bath end surface designed for making contact with orbit boundary is of oval shape having broad and narrow end approximating orbit form. The narrow eye-bath end is raised above its broad end. The electrode is removable and remountable. The eye-bath is manufactured from flexible biologically neutral thermosetting polymer stable with respect to temperature and medicament action.

EFFECT: improved adjacency to orbit in performing electrophoresis procedures.

3 dwg

FIELD: medicine.

SUBSTANCE: method involves dropping 1% midriacyl solution into conjunctival cavity in postoperative period. Then, lidase electrophoresis is applied to orbicular muscle zones. Plaster wetted with Okovidit gel is applied to the lower eyelid.

EFFECT: accelerated treatment course.

FIELD: medicine.

SUBSTANCE: method involves placing active electrode like metal conductor in canal and passive electrode on body surface zone and applying DC action. The metal conductor is coated with dielectric layer spread to its working part. The working part is brought close to impassable area through badly or well-passable zones of the root canal. Gap filled with electrolyte is left between the impassable area and electrode end. The active electrode is connected to electric current source plus terminal and the passive one to minus terminal.

EFFECT: enhanced effectiveness of treatment.

6 dwg

FIELD: medicine.

SUBSTANCE: method involves introducing oxybutinine solution into the urinary bladder via catheter in the amount of 5-10 mg per 20-30ml of sterile water once a day. Electrophoresis is concurrently carried out on the urinary bladder projection region using current intensity of 0.02-0.04 mA/cm2 during 15-20 min. The total treatment course is 10-12 daily procedures long.

EFFECT: enhanced effectiveness of treatment.

1 tbl

FIELD: medicine, juvenile surgery.

SUBSTANCE: the method is characterized by the fact that 3 wk before surgical dissection of adhesions due to laparoscopy one should prescribe bifiform per 1 capsule and Hilak-Forte per 10-15 drops thrice daily. Moreover, 7 d before surgical interference it is necessary to conduct 7 seances of electrophoresis with irucsol and prescribe smekta sorbent per 1 packet thrice daily. Then comes laparoscopic dissection of adhesions, and after surgical interference one should perform electrophoresis with irucsol for 7 d. After appearance of intestinal peristaltics it is necessary to apply smekta per 1 packet thrice daily for 7 d. Since the 8th after operation one should prescribe bifiform per 1 capsule and Hilak-Forte per 10-15 drops thrice daily for 1 mo. Then 1 mo after laparoscopy one should prescribe electrophoresis with collalysine up to 8-10 procedures at simultaneous abdominal massage and curative-physical culture complex for 8-10 d. The method enables to obtain antiadhesive effect in 92% cases of surgical dissection of adhesions due to complex impact upon pathogenesis of adhesive disease, at decreased number of relapses.

EFFECT: higher efficiency of therapy.

2 ex

FIELD: medical engineering.

SUBSTANCE: device has container for keeping product to be applied, dosing unit for distributing the product, power supply element placed near the dosing unit. The dosing unit is designed as rotating element and is apiece of felt. Container walls are flexible. The dosing unit is manufactured from electric conducting material and connected to the power supply element.

EFFECT: enhanced effectiveness in carrying out viscous product iontophoresis.

8 cl, 7 dwg

The invention relates to medicine, namely to dentistry

The invention relates to medical equipment, namely to physical therapy devices, and can be used for the treatment of chronic urethritis and prostatitis

FIELD: medicine.

SUBSTANCE: method involves filling vitreous cavity with perfluororganic compound. Two electrodes manufactured from platinum group metal are intravitreally, transretinally introduced into intraocular neoplasm. Electrochemical destruction is carried out with current intensity of 10-100 mA during 1-10 min in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous, transretinal laser radiation of 661-666 nm large wavelength is applied at a dose of 30-120 J/cm2 in perfluororganic compound medium. The transformed retina and tumor destruction products are intravitreally removed with perfluororganic compound volume being compensated with its additional introduction. Boundary-making endolasercoagulation of retinotomy area is carried out. The perfluororganic compound is substituted with silicon oil. The operation is ended in placing sutures over sclerotmy areas and over conjunctiva. Perfluormetylcyclohexylperidin, perfluortributylamine or perfluorpolyester or like are used as the perfluororganic compound for filling vitreous cavity. Platinum, iridium or rhodium are used as the platinum group metals.

EFFECT: complete destruction of neoplasm; reduced dissemination risk.

6 cl, 12 dwg

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