Helminthicide species

FIELD: medicine, helminthology, chemical-pharmaceutical industry.

SUBSTANCE: invention relates to the creature of medicinal species used for treatment of helminthism of different etiology. Invention proposes the helminthicide species comprising dried fennel seeds, clove fruits, thyme herb, common wormwood herb, tansy flowers, walnut leaves, tumeric roots, valerian roots and licorice roots in the following ratio, mas. p. p.: fennel seeds, 0.8-1.2; clove fruits, 0.4-0.8; thyme herb, 0.4-0.8; common wormwood herb, 0.8-1.2; tansy flowers, 0.8-1.2; walnut leaves, 0.8-1.2; tumeric roots, 0.4-0.6; valerian roots, 0.24-0.36, and licorice roots, 0.4-0.6. Helmithicide species is used as a powder or a powder placed into a capsule. The species elicits high activity in treatment of different parasitic diseases, such as ascariasis, enterobiasis, lamblialis, infection with flat helminthes and this species shows normalizing effect on functional activity of gastroenteric tract.

EFFECT: valuable medicinal properties of species.

4 cl, 4 ex

 

The invention relates to medicine, namely to pharmacotherapy, and can be used as a drug with worms of various etiologies.

It is known that for getting rid of worms, in particular, in the treatment of ascariasis use of anthelminthic drugs are synthetic stimulants: piperazine, nattamon, decaris, etc. (Mashkovsky PPM Medicines, M., 1986, part II, s). These medications can have negative side effects as nausea, abdominal pain, headaches. In case of overdose, for example, piperazine possible muscle weakness, tremor. Contraindications to the use of these drugs are organic diseases of the Central nervous system and the liver.

Another group of drugs are preparations based on vegetable raw materials. Thus, known anthelminthic drug, including verbena officinalis (see Tllat Kazakhstan and other registry biologically active additives to food. Almaty, Leovic, 2000, p.150).

Similar to the proposed invention is a pharmaceutical collection, consisting of the dried leaves of bearberry leaf and dried rosehips in a ratio of components, parts 1:5. The collection is effective in the treatment of giardiasis and opisthorchiasis (patent RU 2148410, 2000). The disadvantage of this collection is the fact that he is not very effective in the treatment of ascariasis, enterobiasis, as well as from tapeworms.

The closest analogue of the proposed invention is an anthelmintic agent, comprising as active ingredients walnuts, pumpkin seeds, wormwood tsitvarnoy, cloves and garlic (see Tllat Kazakhstan and other registry biologically active additives to food. Almaty, Leovic, 2000 s.204). However, this collection has a strongly pronounced astringent properties that can inhibit the excretion of worms with products of metabolism, in addition, it is inefficient giardiasis.

The present invention was to eliminate these shortcomings and the creation of deworming drugs based on vegetable raw materials exhibiting high activity in the treatment of various parasitic diseases such as ascariasis, enterobiasis, giardiasis, an infection of flat worms, and have a normalizing effect on the gastro-intestinal tract.

The problem is solved in that anthelminthic collection based on vegetable raw materials, characterized in that it contains dried fennel seeds, fruits, clove, thyme herb, the herb wormwood, tansy flowers, leaf walnut, turmeric root, Valerian root, and licorice root in the following ratio mass parts:

seeds Fe is Hel 0,8-1,2

carnation fruits of 0.4-0.6

herb thyme 0,4-0,6

herb wormwood 0,8-1,2

tansy flowers of 0.8-1.2

leaf walnut 0,8-1,2

the turmeric root of 0.4-0.6

Valerian root 0,24-0,36

licorice root 0,4-0,6

Offer deworming collection, preferably for the treatment of ascariasis, enterobiasis and giardiasis. He also effective when cescotto (dwarf beef, pork tapeworm, wide lentets). Preferably, it is used in powder form, which can be placed in capsules. It is possible to manufacture tablets on the basis of this collection. It can also be used in the form of infusion or decoction.

The following is a characteristic part of the proposed collection of plants. Fennel (Foeniculum vulgare) is a powerful biennial or perennial plant of the family Umbelliferae, the fruits of which are aromatic, oblong dvusemjanki and have a sweet, slightly spicy taste. The fruits contain up to 6% essential oil, up to 12% of fatty oil, as well as proteins, sugars and other components. Fennel fruit possess anthelmintic (deworming), diuretic and antibacterial effect, promotes digestion.

Clove tree (Syzygium aromaticum) is a perennial tropical plant of the family myrtaceae. Flower buds (fruits) collect not revealed, they contain up to 20% essential oil, consisting the th 96% of eugenol, vanilla and other compounds. Carnation has a strong, distinctive aroma and spicy taste, it is used to improve digestion, and as an antiseptic.

Thyme (thyme) Thymus) is a genus of plants of the Labiatae, its leaves contain essential oils, mainly thymol, a little tannins, bitterness and ploidy. Thyme has antihelminthic (anthelminthic), disinfectant and analgesic action.

Wormwood (Artemisia absinthium) is a perennial herbaceous plant of the Asteraceae family, its leaves contain glycosides (absinthin, anabsintin), essential oil, vitamin C, a small amount of tannins and other substances. Sagebrush increases the secretion of gastric juice, bile and content of the pancreas, stimulates digestion, eliminates spasms of the colon, has anti-inflammatory and antihelminthic effect.

Common tansy (Tanacetum vulgare) is a perennial herbaceous plant of the family Compositae. Medicinal raw are the flowers are collected in baskets. Tansy contains volatile oil, flavonoids, alkaloids, bitter substance tanatsetin, organic acids, including ascorbic, tannins and carotene. She has choleretic, anti-inflammatory, antiseptic, antihelminthic, and astringent.

Walnut'or is x (Juelans regia) - the tree of the walnut family. Medicinal raw materials in the proposed collection are the leaves, which contain many biologically active compounds: aldehydes, essential oil, alkaloids, vitamins C, PP, carotene, phenol carbonic acids, tannins, coumarins, flavonoids, anthocyanins, quinones and aromatic hydrocarbons. Walnut leaves have antibacterial, anti-inflammatory, antihelminthic and tonic effect.

Turmeric (Curcuma longa) is a herbaceous plant of the ginger family. Medicinal raw materials are the root of the plant that contains essential oil, bitterness, curcumin and starch. The root has a strong antioxidant, anti-inflammatory and choleretic effect.

Valerian (Valeriana officinalis) is a perennial herbaceous plant of the family valerianovyh. Medicinal raw materials are biennial rhizomes with roots, which contain essential oil, isovalerianic acid, glycosides, traces of alkaloids, tannins, resinous substances, saponins, organic acids are formic, acetic, malic, palmitic and others. The roots of Valerian has a calming effect on the nervous system, relieve spasm of the coronary vessels, stomach and intestines, and helps improve digestion.

Licorice smooth (Glucyrrhiza glabra) is a herbaceous plant of the legume family Lekarstvennym raw materials are underground roots and shoots, which contain glycerin, sterols and ploidy and take a laxative and a bactericidal effect, regulate water-salt balansky taste of licorice root enhances the taste of other ingredients that are included with the proposed collection, thus accelerating their absorption in the intestine and increases drug action.

Each of the components of medicinal collection approved for use by the Pharmacopoeia.

Included in the collection of the plant is harvested, preferably, in August - early September full moon. It is most preferable to collect plants in 3-5 hours after the storm. Collected raw materials are dried in a dark place at temperature not above 35°C. Then the dried collection of crush and grind into powder. The powder can be placed in soluble in the stomach and intestines capsules.

In the proposed collection of qualitative and quantitative composition of the plant materials chosen experimentally in such a way as to ensure the possibility of detrimental effects on a wide range of parasites with simultaneous recovery of gastrointestinal microflora, improve peristalsis and reduce flatulence. Specified in the claims intervals of concentrations of ingredients are optimal for achieving the above technical result. The plants that individual use of the implement does not exhibit anthelmintic activity, in this collection reinforces the main anthelminthic drugs (flowers of tansy, walnut leaves, fennel fruit and herbs of thyme). The root of the turmeric herb, thyme and Valerian root have strong detoxifying properties, increase mucus compartment, relieve spasms of the intestine, thereby contributing to the successful removal of killed parasites, reduce the intoxication of the organism, resulting from the death of the worms.

Was unexpectedly discovered an additional effect - protivokariosnoe the proposed collection, while Candida destroyed in the mouth, stomach, intestines and genitals.

Preferably, the collection is used as follows. The day before his admission and throughout the treatment period, patients stop eating in the evenings, sweet, yeast dough from wheat flour. The collection is used in a dry (powder form) 1 teaspoon (tsp) (5 g) adults and children aged over 10 years and 1/3 tsp. children up to 10 years for 40 minutes before meals 3 times a day (morning, afternoon and evening). Drink water should not be. You can roll up a powder collecting in the bread and swallowed, drink one or two SIPS of strong green tea or eat 1 tsp of jam from the young fruit of the walnut. Collection use 14 days, then make a break for 3 days and continue the Riem collection within 7 days. If defecation is the output of parasites or their fragments, continue to use collection of 14 days.

Every third day of the adoption of Assembly after a gentle supper (for example, cabbage salad) use a laxative in the form of magnesia or castor oil (1 kg 1 g of castor oil). Instead of a laxative may leaching bowel enemas (2-3 times during the course of treatment).

The present invention is illustrated in the following examples the use of the proposed fee in the treatment of volunteers.

Example 1.

Patient N., 45 years. He complained of abdominal pain, fatigue during the day, memory loss, and condition of hair and nails. The diagnosis of ascariasis confirmed by laboratory analysis of faeces were found Ascaris eggs.

Treatment for the above scheme. In the preparation of the collection of dried ingredients used in the following ratio: seed fennel - 80 g (to 0.8 parts by weight), carnation fruits - 40 g (0.4 parts by weight), herb thyme - 40 g (0.4 parts by weight), herb wormwood - 80 g (to 0.8 parts by weight), tansy flowers - 80 g (to 0.8 parts by weight), leaf walnut - 80 g (to 0.8 parts by weight), turmeric root - 40 g (0.4 parts by weight), Valerian root 24 g (0,24 parts by weight) and licorice root - 40 g (0.4 parts by weight). The ingredients were mixed, crushed and rubbed into powder.

On the 4th day of treatment in the faeces were found floor is rotten roundworm. After a day of fasting and taking castor oil was released over twenty Ascaris size from 10 to 15 cm Treatment continued for months until the disappearance of all symptoms, which turned sick.

Example 2.

Patient M., 53 years old, complained about constant headaches, weight loss, disorders of defecation (1 every 3 days). After the diagnosis is confirmed giardiasis, and enterobiasis.

Treatment for the above scheme. In the preparation of the collection of dried ingredients used in the following ratio: seed fennel - 100 g (1 parts by weight), carnation fruits - 50 g (0.5 parts by weight), herb thyme - 50 g (0.5 parts by weight), herb wormwood - 100 g (1 parts by weight), tansy flowers - 100 g (1 parts by weight), leaf walnut - 100 g (1 parts by weight), turmeric root - 50 g (0.5 parts by weight), Valerian root 30 g to 0.3 parts by weight) and licorice root - 50 g (0.5 parts by weight). The ingredients were mixed, crushed and rubbed into powder.

On the 2nd day of treatment in the faeces found lots of pinworms. On the 3rd day marked decrease in headaches. On the 10th day after the tubage liver headaches disappeared, normal defecation. The treatment lasted over a month to fully cure giardiasis liver and intestines.

Example 3.

Patient N., 17 years, complained about pain in the back right and painful bloating.

Treatment for the above shemei cooking collecting the dried ingredients used in the following ratio: seed fennel - 120 g (with 1.2 parts by weight), carnation fruits - 60 g (to 0.6 parts by weight), thyme herb - 60 g (to 0.6 parts by weight), herb wormwood - 120 g (with 1.2 parts by weight), tansy flowers - 120 g (with 1.2 parts by weight), leaf walnut - 120 g (with 1.2 parts by weight), turmeric root - 60 g (to 0.6 parts by weight), Valerian root 36 g (of 0.36 parts by weight) and licorice root - 60 g (to 0.6 parts by weight). The ingredients were mixed, crushed and rubbed into powder.

On the 2nd day of the adoption of collecting bloating increased, disturbed defecation, after drinking castor oil and soft manipulation of the stomach according to the method Ugulava began defecating. In the next 10 hours left about 90 species Ascaris different sizes. Worms were also in the next week. Pain and bloating disappeared.

Example 4.

Patient G., 25 years, complaints of loss of appetite, nausea, irregular bowel movements, reduce body weight, restless sleep. Diagnosis: candidiasis and cestodes (infection dwarf tapeworm).

Treatment anthelmintic collection, part of which is shown in example 2. A week after the beginning of reception of collection candidiasis of the mouth and genitals was cured, on the 10th day after taking a laxative went dwarf tapeworm. Gone are the symptoms that turned sick.

The presented examples demonstrate the high efficiency of the proposed deworming collection.

1. Antihelminthic collection based on vegetable raw materials, characterized the clinical topics it contains dried fennel seeds, fruits, clove, thyme herb, the herb wormwood, tansy flowers, leaf walnut, turmeric root, Valerian root, and licorice root in the following ratio, parts by weight:

Fennel seeds 0,8-1,2

Carnation fruits 0,4-0,8

Herb thyme 0,4-0,8

Herb wormwood 0,8-1,2

Tansy flowers of 0.8-1.2

Leaf walnut 0,8-1,2

The turmeric root of 0.4-0.6

Valerian root 0,24-0,36

Licorice root 0,4-0,6

2. Antihelminthic collection according to claim 1, characterized in that for the treatment of ascariasis, enterobiasis, giardiasis and custoza.

3. Antihelminthic collection according to claim 1, characterized in that it is used in powder form.

4. Antihelminthic collection according to claim 1, characterized in that it is used in powder form, is placed in the capsule.



 

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