Method of preparing aqueous formulations

FIELD: agrochemistry.

SUBSTANCE: invention provides a stable aqueous formulation of hydrophobic pesticide by emulsifying aqueous phase and a water-immiscible phase, the former containing poly(alkylene glycol) ether and the latter hydrophobic pesticide and one or several emulsifiers selected from group including carboxylate, sulfate, sulfonate, alcohol solutions of ethoxylated and alkylphenolethoxylate, fatty acid ethyl ester, sorbitol ester, ethoxylated fat or oil, aminoethoxylate, ethylene oxide/propylene oxide copolymer, fluorocarbon, and siliceous polymer.

EFFECT: increased stability of formulations.

38 cl, 1 tbl, 12 ex

 

The present invention relates to the field of agrochemical formulations. In particular, the invention relates to aqueous compositions of hydrophobic pesticides that are stable and equally effective compared with conventional compositions.

Hydrophobic pesticides are usually obtained in the form of dry formulations due to their insolubility in water. For example, in U.S. patent 5125958 ("US'958") presents the herbicide ethyl-2-dichloro-5-[4- (deformity) -4, 5-dihydro-3-methyl-5-oxo-1H-1, 2, 4-triazole-1-yl]-4-perbandaran (carfentrazone), viscous oily liquid, which can be obtained in the form of granules with a relatively large particle size, as powdery dust, as wettable powders, as emulsifiable concentrates, as solutions or any of several other known types of formulations. In addition, in the US' 958 also describes the possibility of obtaining carfentrazone in the form of a water-soluble or water-insoluble granules, in which the water rather serves as a means of applying the composition than is a component of the composition. Furthermore, in U.S. patent 5935905 ("US'905") presents the dry composition of carfentrazone and N-(phosphonomethyl)glycine (glyphosate). As in the US'958, and in the US' 905 requires the absorption of technical grade carfentrazone on the media to form carfentrazone. Although it was assumed that the compositions have a DL is positive shelf life when stored, it was found that they have a tendency to hydrolysis and therefore are not stable. As a result there is a need for formulations of hydrophobic pesticides, in particular carfentrazone with greater stability.

The invention

The present invention relates to new formulations of pesticides, which are water, economical, environmentally acceptable and are less prone to hydrolysis or lack of it over time, thus leading to an increase in stability characteristics in relation to the activity of the pesticide. By reducing or minimizing the use of organic solvents eliminates the costs and risks associated with the disposal of such materials. In addition, the process can be carried out on relatively simple equipment using relatively simple stage of the process.

According to one embodiment, the present invention relates to pesticide effective, stable aqueous formulations of hydrophobic pesticides.

According to one aspect of the invention, the composition contains water emulsion (EW), which consists of an aqueous phase comprising water and optional agent freeze/ thaw, one or more emulsifiers or combinations thereof, and is not miscible with water phase comprising a hydrophobic n is stice and one or more emulsifiers.

According to another aspect of the invention, provided the pesticide composition of hydrophobic pesticide comprising the above aqueous composition in combination with one or more pesticides.

Also according to the present invention provides a process of obtaining the above-mentioned water emulsions (EW) or pesticide formulations above water emulsion in combination with one or more additional pesticides.

Definition

Applied here, the modifier “about” means that the basic preferred operating ranges, such as ranges for the molar ratios of reactants, amount of substance, and temperature, are not strictly defined. Values are often obvious to the person skilled in the art. For example, for a temperature range from about 120°With up to approximately 135°With respect, for example, organic chemical reactions can be interpreted as the inclusion of other similar temperatures, which potentially can support a significant reaction rate, such as 105°or 150°C. In the absence of the experience of a specialist in this area is the lack of leadership context, and unless more specifically below, the range for “approximately” should not be b is more than 10% of the absolute values of the end points or 10% of the specified range, any small.

Used herein, and unless stated otherwise, values of deputies “alkyl”, “cycloalkyl”, “alkoxy”, “aryloxy and alkoxyimino”used alone or as part of a larger sequence, include unbranched or branched chain, at least one or two carbon atoms respectively to the Deputy and preferably up to 20 carbon atoms, more preferably up to 10 carbon atoms, most preferably up to 7 carbon atoms. “Halogen” means fluorine, bromine, iodine or chlorine. “Aryl” means an aromatic ring structure containing 5 to 10 carbon atoms. Used here, the term “ambient temperature” can mean any suitable temperature, appropriate laboratory or other workplace, and usually be at least about 15°S, but not higher than about 30°C.

The term “aqueous phase”as used here, refers to water or a mixture of water and hydrocarbon solvent, easily emulsifiable in water. Preferably the aqueous phase contains at least about 50% V/V, more preferably about 95% V/V water.

Used herein, and unless specified otherwise, the term “pesticide” refers to a molecule or combination of molecules that TSOs shall raise, detain or kill pests, such as, without limitation, harmful or annoying insects, weeds, caterpillars, mushrooms, bacteria and the like, and can be used for plant protection, protection of buildings, protection of turf or security of the person; the pesticides include, but are not limited to, herbicides, insecticides, acaricides, fungicides, protection from nematodes and ectoparasites and growth regulators as used to support the growth of desirable plant species, and to delay the growth of unwanted weeds.

Detailed description of the invention

In General the present invention relates to aqueous compositions of hydrophobic pesticide, comprising emulsifying the aqueous phase and is not miscible with water phase to obtain a composition, where the water-immiscible phase comprises a pesticide and one or more suitable emulsifiers. Preferably the aqueous phase includes a suitable agent freeze/thaw or one or more suitable emulsifiers, or a combination thereof. Examples of hydrophobic pesticides that can be used in the present invention include, but are not limited to, carfentrazone, sulfentrazone, clomazone, permethrin, zetacypermetrin, bifenthrin. The preferred pesticide produced using the present invention, is carfentrazone.

The compositions according to the but the present invention is supposedly prevent or delay the hydrolysis of the pesticide. Essentially they are equivalent, if not greater stability compared to compositions described in this field. In addition, the compositions according to the present invention provide a homogeneous distribution of hydrophobic pesticide within the structure.

According to one embodiment of the present invention, the aqueous phase is added to the water-immiscible phase. The compound obtained using the following steps:

a) preparation of an aqueous phase comprising water;

b) preparation of water-immiscible phase containing the hydrophobic pesticide and one or more emulsifiers;

c) adding the aqueous phase to the water-immiscible phase;

and (d) emulsifying the mixture to obtain a composition.

According to another embodiment of the present invention, the water-immiscible phase is added to the aqueous phase. The compound obtained using the following steps:

e) preparation of water-immiscible phase containing the hydrophobic pesticide and one or more emulsifiers;

f) preparation of an aqueous phase comprising water;

g) adding a water-immiscible phase to the aqueous phase; and

h) the emulsification of the mixture to obtain a composition.

Emulsification is preferably carried out in the temperature range from approximately 20°C to 80°more preferred is compulsory from about 20° With up to 70°C. Preferably, the emulsification is carried out during the period exceeding approximately 3 min; and according to one embodiment, during the period up to about 24 hours; more preferably approximately from 5 minutes to 3 hours. The emulsification can be carried out at lower temperatures, such as below 15°but will usually require significantly more time to complete.

Suitable emulsifiers which can be used in the context of the present invention are those substances that are active on the interface of oil and water and which help to reduce the surface tension of the oil, thus leading to the formation of a stable and homogeneous mixture.

Examples of emulsifiers that may be used include, but are not limited to, carboxylates, sulfates, sulfonates, alcohol ethoxylates, apes, ethoxylates of fatty acids, esters of sorbitol, ethoxylated fats or oils, aminexil, esters of phosphoric acid, copolymers of ethylene oxide and propylene oxide, fluorocarbons and silicon polymers. Preferred emulsifiers that can be used are alkylpolyglycoside resin, polyalkylene glycol ether, polyalkoxysiloxanes nonylphenyl, alkoxycarbonyl primary alcohol, amoxillian the th distillery, the ethoxylated distyrylbenzene, the ethoxylated muistiinpanoista, ester of muistiinpanoista, gidroksilirovanii polymer stearic acid and polyalkyleneglycol and their corresponding salts. Particularly preferred emulsifiers which can be used according to the present invention, are alkylpolyglycoside resin, polyalkylene glycol ether, an ethoxylated distillery, the ethoxylated distyrylbenzene, the ethoxylated muistiinpanoista, ester of muistiinpanoista and potassium salt of muistiinpanoista.

According to another embodiment of the present invention the aqueous phase may contain the agent of freezing/thawing and one or more emulsifiers. Examples of agents of freezing/thawing, also related to cryoprotectants, which can be used according to the present invention, include, but are not limited to, monoethylene glycol, propylene glycol, glycerin, urea and inorganic salts. Preferred used by the agent to freezing/thawing is propylene glycol. The emulsifiers described above, can also log into the aqueous phase. The preferred emulsifier used in the aqueous phase is a copolymer of ethylene oxide and propylene oxide.

According to another embodiment of the present invention,the water-immiscible phase may also contain a hydrocarbon solvent. Suitable hydrocarbon solvents are those in which may be soluble water-immiscible phase. Examples of hydrocarbon solvents that can be used in the present invention include, but are not limited to, alkylated naphthalene aromatic compounds, alkylated biphenyls, hydrogenated aliphatic compounds, ISO, paraffins, cycloparaffins, aromatic compounds, a number of xylene, allylacetate, fatty acids, esters, mineral and vegetable oils and olefins. Preferred hydrocarbon solvents that can be used in the present invention are alkylated naphthalene aromatic compounds and alkylated biphenyls.

A typical composition according to the present invention will typically contain from about 1 to 50, preferably from about 2 to 30 wt.% pesticide, from about 10 to 25, preferably from about 5 to 10 in the amount of wt.% one or more emulsifiers and from about 30 to 80, preferably from about 30 to 75 wt.% water. An alternative preferred embodiment according to the present invention includes from about 2 to 15, preferably from about 4 to 10% of the mass. agent freeze/thaw in addition to visualase is clinically typical composition. Another preferred alternative embodiment, also includes from about 1 to 50, preferably from about 4 to 25 wt%. hydrocarbon solvent in addition to the above typical composition. Still another preferred embodiment combines the above typical composition, agent, freeze/thaw and a hydrocarbon solvent, in each of the above concentrations. Another further preferred embodiment is a composition containing the above ingredients according to the typical structure, with the presence or absence of the agent, freeze/thaw, with the presence or absence of a hydrocarbon solvent plus any other suitable ingredient, such as, but not limited secondary pesticide, biocide, thickener and similar ingredients are typically included in the well-known in this field formulations of pesticides, many of which are presented here below.

After preparation of the composition range of the particle size of the pesticide is usually approximately from 0.01 μm to 100 μm, preferably approximately from 0.01 μm to 10 μm. Working conditions the escape of particles of the desired size will depend on a number of factors, including, where appropriate, the temperature of the holding of emulsification, the speed of addition of the reagents used for amulya the project equipment, the number of the used emulsifiers and the like. For example, smaller particles are usually obtained when using more emulsifiers and a longer time of emulsification. In light of the present description of the conditions governing the receipt of the emulsions in accordance with the present invention, are well known in the prior art.

After completion of the emulsification, compositions can be added additives. The number of added after emulsification additives is the same for all embodiments and is usually selected from one or more from about 0.003 to 1, preferably about 0.005 to 0.5% of the mass. defoamer, such as polydimethylsiloxane; from about 0.003 to 1, preferably about 0.005 to 0.5% of the mass. thickener, such as xanthan gum or ethyl - or methyl cellulose; approximately from 0.01 to 0.5, preferably from about 0.01 to 0.1% of the mass. one or more bactericidal substances; about 0.05, preferably approximately 0.04% of the mass. inert dye; and approximately 10% of the mass. one or more surfactants, each percentage of the mass corresponds to the mass of the composition after addition of the additives.

The compositions according to the present invention can apply to the Department of the but or an effective amount of the pesticide composition, for example, from about 2 to about 50 wt. -%, can be combined with an effective amount of, for example, from 50 to 98% of the mass. one or more additional pesticides to ensure a broader spectrum of activity compared with the conventional compositions comprising only one pesticide. Examples of additional pesticides that are acceptable according to the present invention, include, but are not limited to, glyphosate, (2,4-dichlorophenoxy)acetic acid (2,4-D), (4-chloro-2-methylphenoxy)acetic acid (MSRA), (RS)-2-(4-chloro-ortho-tolyloxy)propionic acid (MSRR), Isoproturon, imazapyr, imazamethabenz, imazethapyr, imazighen, alfthan, bifenox, fomesafen, ioxynil, bromoxynil, chlorimuron, chlorsulfuron, encultured, pyrazosulfuron, thifensulfuron, triasulfuron, fenoxaprop, fluazifop, hisamoto, diclofop, bentazon, butachlor, dicamba and peroxides. Preferred additional pesticide is glyphosate.

The compositions according to the present invention is further illustrated by the procedures presented below in the examples. The examples serve only to illustrate the invention and may not be interpreted as limiting since further modifications of the described invention will be apparent to experts in this field. All such modifications are carried out within the framework of the invention, as in asana in the claims.

Example 1

This example illustrates the retrieval Protocol 4 g/l microemulsion (4 ME) composition (composition A).

A mixture of 4 g of 90% pure carfentrazone (supplied by the firm FCM Corporation), 8 g of alkylated naphthalene aromatic solvent (Aromatic 200 ND, the company supplied echop Chemical Company, Houston TX), 8 g of ethoxylated distillery containing 15 moles of ethylene oxide (Soprophor DS/15 supplied by the company Rhone-Poulenc, Inc. Newark, NJ), 8 g of ethoxylated distyrylbenzene containing 15 moles of ethylene oxide (Soprophor DSS/15 supplied by the company Rhone-Poulenc, Inc.) and 70 g of deionized water were mixed manually at ambient temperature for 2 min to obtain the emulsion. The emulsion was heated to approximately 70°From where then mixed by hand for 2 minutes After that, the emulsion was cooled to ambient temperature and was added 2 g of ethoxylated muistiinpanoista containing 4 mol of ethylene oxide (Soprophor DV4624 supplied by the company Rhone-Poulenc, Inc.). After adding the emulsion was again heated to 70°and further stirred by hand for 2 minutes At the end of this period, the emulsion was cooled to ambient temperature to obtain a microemulsion.

Example 2

This example illustrates the retrieval Protocol 240 g/l of emulsion (240 EW) composition (composition B).

The mixture to 95.3 g of water, 15 g of the ester of p is dialkylamines (Atlas G-5000, supplied by the company Imperial Chemical Industries (ICI), Bayonne, NJ) and 10.5 g of propylene glycol were heated to 70°to achieve dissolution. In a separate mixing vessel, the mixture 59,25 g 91% pure carfentrazone, 60 g of alkylated naphthalene aromatic solvent (Solvesso 200, the company supplied echop Chemical Company) and 10 g alkylpolyglycoside resin (Atlox® 4914 supplied by the company ICI), was heated to 55°and mixed manually for 5 minutes After this period obtained above aqueous solution of propylene glycol was added for 30 s, using a mixer transmitter station A3000 (supplied by the firm Brinkmann Instruments, Inc., Westbury, NY). The resulting mixture was heated to approximately 55-65°and was stirred for 20 minutes At the end of this period, was added an additional 10 g alkylpolyglycoside resin (Atlox® 4914 supplied by the company ICI) for 2 min, maintaining the temperature of 55°C. After complete addition, the mixture was cooled to 30°and was stirred for 2 min at 300 rpm to obtain an emulsion.

Example 3

This example illustrates the retrieval Protocol 240 g/l of emulsion (240 EW) composition (composition C).

This composition was obtained by the method described in example 2, with the difference that the emulsification took place preferably at 50°C than at 55°C.

Example 4

This example illustrates the retrieval Protocol composition, including the nes, carfentrazone and glyphosate (composition D).

A mixture of the 39.6 g of the composition 240 EW containing carfentrazone obtained by the method described in example 2, and 60,4 g (N-phosphonomethyl)glycine (glyphosate) (supplied by the company Monsanto Company, St. Louis, MO) was stirred in a glass 1 liter for 5 min at 600 rpm using a mixer Model LiU08 (supplied by the company Lightnin, Rochester, NY).

Example 5

This example illustrates the retrieval Protocol 240 g/l of emulsion (240 EW) composition (composition F).

Carfentrazone, 90,6% clean, 221,44 g was heated to approximately 40-45°and added 24 g of bis(methylethyl)-1,1/-biphenyl (supplied by the firm as NuSolv™ ABP-103 Ridge Technologies, Inc., Ridgewood/ NJ) and 16 g epoxidizing soybean oil (supplied as Drapex® 6.8 for the company Witco Corp., Oakland, NJ). After complete addition, the mixture was stirred for 5 min using an electric mixer, Kitchen Aid Type and then added to 96 g of a mixture comprising monomodality and dividendnyj muistiinpanosovelma esters and the corresponding potassium salt (supplied in the form of Soprophor FLK-40 company Rhone-Poulenc, Inc.) and 16 g of ethoxylated nonionic of christianfree (supplied by the firm as Soprophor BSU in Rhone-Poluenc, Inc.). The resulting mixture was stirred for 5 minutes After this period added 356,6 g of warm water (45°C) for 5 min followed by the addition of 80 g of an aqueous solution containing 2% xanthan resin (supplied in the form of Rhodopol 23 firm R.T. Vanderilt Co., Inc. Norwalk, Ct) and 0.1% antimicrobial biocide (supplied in the form of Legent MK™ firm Rohm and Haas Co., Philadelphia, PA). After complete addition, the resulting mixture was stirred for 2 hours at 400 rpm to obtain an emulsion.

Example 6

This example illustrates the retrieval Protocol 240 g/l of emulsion (240 EW) composition (composition F).

This composition was obtained by the method described in example 5 with the difference that the temperature of emulsification and water was preferable 40°than 45°C.

Example 7

This example illustrates the retrieval Protocol 4 g/l microemulsion (4 ME) composition (composition G).

A mixture of 5 g of 91.8% pure carfentrazone, 5 g of alkylated naphthalene aromatic solvent (Aromatic 200 ND), 1.5 g of a patented combination of emulsifiers specified as Sponto 4289, RDB 10/168 (supplied by the company Witco Corp.) and 13.5 g patented combination of emulsifiers specified as Sponto 4290, RD 10/164 (also supplied by the company Witco Corp.), was heated to approximately 40°With, mixing this by hand for 2 minutes After this period were added 75 g of deionized water to obtain an emulsion. After complete addition, the emulsion was heated to 40°and further stirred by hand for 2 minutes At the end of this period, the emulsion was cooled to ambient temperature to obtain a microemulsion.

When is EP 8

This example illustrates the retrieval Protocol 240 g/l of emulsion (240 EW) composition (composition H).

To a mixture of 28 g of permethrin, 4 g of bis(methylethyl)-1,1'-biphenyl (NuSolv™ AVR-103) and 2 g epoxidizing soybean oil (Drapex® 6.8 cm) was added 12 g of a mixture containing monomodality and dividendnyj muistiinpanosovelma esters and the corresponding potassium salt (Soprophor FLK-40) and 16 g of ethoxylated nonionic of christianfree (Soprophor BSU). After complete addition, the mixture was stirred at ambient temperature for 20 min, using the mixer Kitchen Aid Type. After this period added to 44.5 g of water followed by the addition of 7.5 g of an aqueous solution containing 2% xanthan gums (Rhodopol 23). After complete addition, the resulting mixture was stirred for 2 hours at 400 rpm to obtain an emulsion.

Example 9

This example illustrates the retrieval Protocol 240 g/l of emulsion (240 EW) composition (composition J).

This composition was obtained by the method described in example 8, with the difference that applied preferable zetacypermetrin than permethrin.

Example 10

This example illustrates the retrieval Protocol 400 g/l of emulsion (400 EW) composition (composition C).

A mixture of to 219.5 g of water, 28,75 g ether polyalkyleneglycol (Atlas G-5000) and 0.5 g of 100% of the antifoam polydimethylsiloxane (Dow Corning® 1520, Dow Corning Corporation, Midland, MI) was heated to 50°With the achievement of the possible dissolution. In a separate vessel for mixing the mixture of 210,65 g 91.3% of net clomazone, 19,35 g alkylated naphthalene aromatic solvent (Aromatic 200 ND) and 21.25 g alkylpolyglycoside resin (Atlox® 4914) was heated to 50°to achieve dissolution and then mixed manually for 5 minutes After this period added vyshepredstavlennyh aqueous solution of antifoam, using the mixer Silverson L4RT (supplied by the company Silverson Machine LTD., England). The resulting mixture was cooled to 30-40°and was stirred for 18 min at 3000-7000 rpm to obtain an emulsion. At the end of this period the mixture was stirred for 1 h at 300 rpm to obtain an emulsion.

Example 11

This example illustrates the retrieval Protocol 100 g/l of emulsion (240 EW) composition (composition L).

Stir a mixture of 128,4 g bifenthrin and 447,6 g alkylated naphthalene aromatic solvent (Aromatic 200 ND) was heated to 50°to achieve dissolution. In a separate vessel for mixing the mixture of 443,4 g of water, 60 g of the ester polyalkyleneglycol (Atlas G-5000), 0.6 g of antimicrobial biocide (Legend MK™) and 72 g of propylene glycol was stirred for 10 min using a mixer Silverson L4RT. After this period, added cooked above solution bifenthrin within a 5-minute period at 5600 rpm, using a mixer Silverson L4RT. The resulting mixture was stirred in ECENA 20 minutes At the end of this period, was added 48 g alkylpolyglycoside resin (Atlox® 4914) during the 5-minute period at 3600 rpm, using a mixer Silverson L4RT. After complete addition, the mixture was stirred and left to cool to ambient temperature to obtain an emulsion.

Example 12

The stability studies

This example represents the stability studies conducted in the compositions obtained according to the present invention.

Laboratory tests showing the stability of the emulsion (EW) of the compounds was carried out as follows. Before conducting stability tests have determined the initial percentage of the active ingredient (carfentrazone)present in the above compositions C, E and F, using the methods of chromatography. After this definition, the compositions were stored at 54°within two weeks, one month and three months. At the end of each of these periods was determined by the percentage of active ingredient present in the compositions, using the same techniques of chromatography. The results of these tests are presented in table 1 below.

CompositionThe percentage of the active ingredient1
Temperature CEF
 A.T.254°A.T.54°A.T.54°
The initial portion of the

2-week dose

1-month dose

3-month dose
21,6

-

22

21,7
-

22,4

22,4

22
24,7

-

-
-

23,5

24,6

24,3
25,0

-

25,2

to 25.3
-

-

24,7

24,5
1The average of two repeated measurements.
2The ambient temperature.

The results presented in table 1 show that the compositions of the EW according to the present invention retain their stability at elevated temperature.

Although this invention is described with emphasis on the preferred embodiments, it will be obvious to the person skilled in the art that can be applied variations in the preferred schemes and ways and means, that the invention may be implemented otherwise than specifically described herein. Accordingly, this invention includes all modifications included in the nature and scope of the invention that is specified after the existing claims.

1. The method of obtaining a stable aqueous composition of hydrophobic pesticide, including emulsification of the aqueous phase and the water-immiscible phase, sufficient for homogeneous distribution of the pesticide within the stock;

(a) where the water-immiscible hydrophobic phase contains a pesticide, and one or more emulsifiers selected from the group comprising carboxylate, sulfate, sulfonate, alcohol ethoxylate, alkylphenolethoxylate, ethoxylates of fatty acids, esters of sorbitol, ethoxylated fat or oil, aminexil, copolymer of ethylene oxide and propylene oxide, alkylpolyglycoside resin, the ethoxylated muistiinpanoista, ester of muistiinpanoista, fluorocarbon and silicone polymer, and

b) where the aqueous phase contains an emulsifier of polyalkyleneglycol ether.

2. The method according to claim 1, where the pesticide is selected from the group comprising carfentrazone, sulfentrazone, clomazone, permethrin, zetacypermetrin, bifenthrin.

3. The method according to claim 2, where the pesticide is carfentrazone.

4. The method according to claim 1, where the aqueous phase includes the agent of freezing/thawing.

5. The method according to claim 1, where the emulsification includes mixing the aqueous phase and the water-immiscible phase at a temperature of from about 20 to 80°C for approximately 3 minutes to 24 hours

6. The method according to claim 5 where the emulsification includes mixing the aqueous phase and the water-immiscible phase at a temperature of from about 20 to 70° C for about from 5 minutes to 3 hours

7. The method according to claim 1, where the emulsifiers included in the water-immiscible phase selected from the group comprising alkylpolyglycoside resin, polyalkoxysiloxanes nonylphenyl, alkoxycarbonyl primary alcohol, an ethoxylated distillery, the ethoxylated distyrylbenzene, the ethoxylated muistiinpanoista, ester of muistiinpanoista, gidroksilirovanii polymer stearic acid and polyalkyleneglycol and their corresponding salts.

8. The method according to claim 7, where the emulsifiers selected from the group comprising alkylpolyglycoside resin, the ethoxylated distillery, the ethoxylated distyrylbenzene, the ethoxylated muistiinpanoista, ester of muistiinpanoista and potassium salt of muistiinpanoista.

9. The method according to claim 4, where the agent freeze/thaw selected from the group comprising monoethylene glycol, propylene glycol, glycerin, urea and inorganic salts.

10. The method according to claim 1 where the water-immiscible phase further comprises a hydrocarbon solvent.

11. The method according to claim 10, where the hydrocarbon solvent is selected from the group comprising alkilirovanie naphthalene aromatic compound, alkilirovanny biphenyl, gidrirovannoe aliphatic compound, isoparaffin, aromatic connection is giving a series of xylene, alkyl acetate, fatty acid, ester, mineral oil, vegetable oil and olefin.

12. The method of obtaining a stable aqueous composition of hydrophobic pesticide, including emulsification of the aqueous phase and the water-immiscible phase, sufficient for homogeneous distribution of the pesticide within the structure:

(a) where the water-immiscible hydrophobic phase contains pesticide and Alcide-polietilenglikoli resin;

b) where the aqueous phase contains an emulsifier of polyalkyleneglycol ether.

13. The method according to claim 11, where the hydrocarbon solvent is alkilirovanny naphthalene aromatic compound.

14. The method according to item 12, where the pesticide is selected from the group including carfentrazone, sulfentrazone, clomazone, permethrin, zetacypermetrin, bifenthrin.

15. The method according to 14, where the pesticide is carfentrazone.

16. The method according to item 12, where the aqueous phase contains the agent freeze/thaw selected from the group comprising monoethylene glycol, propylene glycol, glycerin, urea and inorganic salts.

17. The method according to item 12, where the water-immiscible phase further comprises a hydrocarbon solvent selected from the group comprising alkilirovanie naphthalene aromatic compound, alkilirovanny biphenyl, gidrirovannoe aliphatic compound, isoparaffin, aromati the definition connection of a number of xylene, alkyl acetate, fatty acid, ester, mineral oil, vegetable oil and olefin.

18. The method according to 17, where the hydrocarbon solvent is alkilirovanny naphthalene aromatic compound.

19. The method according to item 12, where the emulsification includes mixing the aqueous phase and the water-immiscible phase at a temperature of from about 20 to 80°C for approximately 3 minutes to 24 hours

20. The method according to claim 19, where the emulsification includes mixing the aqueous phase and the water-immiscible phase at a temperature of from about 20 to 70°C for about from 5 minutes to 3 hours

21. Stable aqueous pesticide composition, including:

a) a water-immiscible phase containing the hydrophobic pesticide and one or more emulsifiers selected from the group comprising carboxylate, sulfate, sulfonate, alcohol ethoxylate, alkylphenolethoxylate, ethoxylates of fatty acids, esters of sorbitol, ethoxylated fat or oil, aminexil, copolymer of ethylene oxide and propylene oxide, alkylpolyglycoside resin, the ethoxylated muistiinpanoista, ester of muistiinpanoista, fluorocarbon and silicone polymer, and

b) the aqueous phase containing the emulsifier of polyalkyleneglycol ether.

22. Stable aqueous pesticide composition according to item 21, where the pesticide is selected the C group, including carfentrazone, sulfentrazone, clomazone, permethrin, zetacypermetrin, bifenthrin.

23. Stable aqueous pesticide composition according to item 22, where the pesticide is carfentrazone.

24. Stable aqueous pesticide composition according to item 21, optionally containing one or more pesticides selected from the group comprising glyphosate, (2,4-dichlorophenoxy)acetic acid, (4-chloro-2-methylphenoxy)acetic acid, (RS)-2-(4-chloro-ortho-tolyloxy)-propionic acid, Isoproturon, imazapyr, imazamethabenz, imazethapyr, imazighen, alfthan, bifenox, fomesafen, ioxynil, bromoxynil, chlorimuron, chlorsulfuron, encultured, pyrazosulfuron, thifensulfuron, triasulfuron, fenoxaprop, fluazifop, hisamoto, diclofop bentazon, butachlor, dicamba and peroxides.

25. Stable aqueous pesticide composition according to item 21, where the aqueous phase further includes the agent of freezing/thawing.

26. Stable aqueous pesticide composition A.25, where the agent freeze/thaw selected from the group comprising monoethylene glycol, propylene glycol, glycerin, urea and inorganic salts.

27. Stable aqueous pesticide composition according to item 21, where the emulsifiers included in the water-immiscible phase selected from the group including Alcide-polietilenglikoli resin, polyalkoxysiloxanes nonylphenyl, maxilliofacial primary alcohol, the ethoxylated distillery, the ethoxylated distyrylbenzene, the ethoxylated muistiinpanoista, ester of muistiinpanoista, gidroksilirovanii polymer stearic acid and polyalkyleneglycol and their corresponding salts.

28. Stable aqueous pesticide composition according to item 27, where the emulsifiers selected from the group including Alcide-polietilenglikoli resin, the ethoxylated distillery, the ethoxylated distyrylbenzene, the ethoxylated muistiinpanoista, ester of muistiinpanoista and potassium salt of muistiinpanoista.

29. Stable aqueous pesticide composition containing:

a) not miscible with water phase containing a hydrophobic pesticide and Alcide-polietilenglikoli resin, and

b) the aqueous phase containing the emulsifier of polyalkyleneglycol ether.

30. Stable aqueous pesticide composition according to item 21, where the water-immiscible phase further comprises a hydrocarbon solvent.

31. Stable aqueous pesticide composition according to item 30, where the hydrocarbon solvent is selected from the group comprising alkilirovanie naphthalene aromatic compound, alkilirovanny biphenyl, gidrirovannoe aliphatic compound, isoparaffin, aromatic connection of a number of xylene, alkyl acetate, fatty acid, ester, mineral m the words, vegetable oil and olefin.

32. Stable aqueous pesticide composition according to p, where the hydrocarbon solvent is alkilirovanny naphthalene aromatic compound.

33. Stable aqueous pesticide composition according to clause 29, where the pesticide is selected from the group comprising carfentrazone, sulfentrazone, clomazone, permethrin, zetacypermetrin, bifenthrin.

34. Stable aqueous pesticide composition according to p, where the pesticide is carfentrazone.

35. Stable aqueous pesticide composition according to clause 29, optionally containing one or more pesticides selected from the group comprising glyphosate, (2,4-dichlorophenoxy)acetic acid, (4-chloro-2-methylphenoxy)acetic acid, (RS)-2-(4-chloro-ortho-tolyloxy)-propionic acid, Isoproturon, imazapyr, imazamethabenz, imazethapyr, imazighen, alfthan, bifenox, fomesafen, ioxynil, bromoxynil, chlorimuron, chlorsulfuron, encultured, pyrazosulfuron, thifensulfuron, triasulfuron, fenoxaprop, fluazifop, hisamoto, diclofop bentazon, butachlor, dicamba and peroxides.

36. Stable aqueous pesticide composition according to clause 29, where the aqueous phase comprises the agent freeze/thaw selected from the group comprising monoethylene glycol, propylene glycol, glycerin, urea and inorganic salts.

37. Stable aqueous pesticide composition pop, where the water-immiscible phase further comprises a hydrocarbon solvent selected from the group comprising alkilirovanie naphthalene aromatic compound, alkilirovanny biphenyl, gidrirovannoe aliphatic compound, isoparaffin, aromatic connection of a number of xylene, alkyl acetate, fatty acid, ester, mineral oil, vegetable oil and olefin.

38. Stable aqueous pesticide composition according to clause 37, where the hydrocarbon solvent is alkilirovanny naphthalene aromatic compound.



 

Same patents:

FIELD: agriculture, in particular herbicide compositions.

SUBSTANCE: invention relates to weed controlling method for tolerant cotton crops using (A) road spectrum herbicides selected from group (A1) glufosinate (salt) and related compounds; (A2) glyphosate (salt) and related compounds; and (B) herbicides selected from group containing diurone, trifluraeline, linuron, and pendimethalin; lactofen, oxyfluoren, bispiribac and salts thereof, pyrithiobac and salts thereof; setoxydim, cyclosidim, and cletodim; wherein components (A) and (B) are used in synergistically effective ratio. Also are described herbicide compositions containing compound from group (A1) or (A2) and herbicide from group (B).

EFFECT: effective controlling of weeds in cotton crops.

9 cl, 12 tbl, 3 ex

FIELD: agriculture, in particular method for controlling of weeds.

SUBSTANCE: claimed method for controlling of weeds in tolerant maize cultures includes application of composition comprising (A) road spectrum herbicide from group (A1) glufosinate (salt) and analogs, (A2) glyfosate (salt) and analogs; (B) one or more herbicides from group (B1) cyanazin, alachlor, nicosulfurone, rimsulfurone, sulkotrion, mesotrion, and penthoxamid; (B2) pendimethalyne, methosulam, isoxaflutol, metribuzin, chloransulam, flumetsulam, linuron, florasulam, and isoxachlorotol; and (B3) bromoxinyl, chlorpyralid, tifensulfuron, MCPA (2-methyl-4-chlorophenoxyacetic acid), halosulfuron, and sulfosulfuron, wherein (A) and (B) components are in synergic effective ration. Also disclosed are herbicidal compositions including compound from group (A1) or )F2) and herbicide from group (B).

EFFECT: effective controlling of weeds in tolerant maize cultures.

6 cl, 55 tbl, 3 ex

FIELD: agriculture, in particular herbicide compositions.

SUBSTANCE: invention relates to weed controlling method for tolerant grain crops using (A) road spectrum herbicides selected from group (A1) glufosinate (salt) and related compounds; (A2) glyphosate (salt) and related compounds; and (B) one or more herbicides selected from group containing (B1) herbicides selectively effecting in grain crops especially against monocotyledonous weeds effecting on folia and/or soil (residual benefit); or (B2) herbicides selectively effecting in grain crops against monocotyledonous or dicot weeds effecting especially on folia; or (B3) herbicides selectively effecting in grain crops against monocotyledonous or dicot weeds effecting on folia or soil; or (B4) herbicides selectively effecting in grain crops against monocotyledonous or dicot weeds effecting on folia; wherein components (A) and (B) are used in synergic ration. Also are described herbicide compositions containing (A1) ) glufosinate (salt) and related compounds and herbicide from group (B); as well as herbicide compositions containing(A2) glyphosate (salt) and related compounds and herbicide from group (B); wherein components (A) and (B) are used in synergically effective ration.

EFFECT: effective controlling of weeds in grain crops.

6 cl, 70 tbl, 3 ex

FIELD: organic chemistry, herbicides, agriculture.

SUBSTANCE: invention describes a synergistic composition of herbicides comprising components (A) and (B) wherein (A) represents herbicide taken among the group of the formula (I):

wherein R1 means (C1-C4)-alkyl; R2 means (C1-C4)-alkyl; R3 means hydrogen atom; X and Y mean (C1-C4)-alkoxy-group; (B) represents one or two herbicides taken among the group of compounds or their acceptable forms: alachlor, metolachlor, acetochlor, dimetenamide, atrazine, cyanasin, metribusin, fluthiamide, nicosulfuron, rimsulfuron, primisulfuron, pendimetalin, sulcotrion, dicamba, mesotrion, isoxachlortol, metosulam, anilofos, fenoxaprop-ethyl, setoxydim, diclofop-methyl, MCPA, bromoxynil, pyridat, clopyralid, iodosulfuron-methyl, ethoxysulfuron, amidosulfuron, gluphosinat-amminium, isopropylammonium-glyphosate, imasetapir wherein components (A) and (B) are taken in the effective doses. Also, invention describes a method for control of weeds by using above indicated herbicide composition. Invention provides the development of the synergistic herbicide composition eliciting high activity.

EFFECT: improved method for control, valuable properties of composition.

6 cl, 26 tbl, 3 ex

The invention relates to the field of plant protection products that can be used against weeds in tolerant or resistant crops sugar beet and which as a herbicide biologically active substances contain a combination of two or more herbicides

The invention relates to systems of surfactants for liquid water or water-organic compositions containing mainly organic and aqueous phase in the form of a microemulsion

The invention relates to chemical herbicides used for the destruction of unwanted vegetation

FIELD: plant protection.

SUBSTANCE: method is characterized by that grain-crops in vegetation phase are treated with mixture of methylheptenone with Deciss taken at volume ratio (1-5):1.

EFFECT: reduced toxic pesticide loading on plants in vegetation phase.

1 tbl

The invention relates to the production of pesticides primarily for the protection of plants from harmful insects

The invention relates to a preparative forms of pesticides and allows you to increase the activity and duration of action insecticide and insecticide and acaricide preparative forms based on synthetic pyrethroids

The invention relates to oil insecticidal compositions based on active ingredients-cyano-3-phenoxybenzyl-CIS-2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylate known as cypermethrin and beta-cypermethrin, and (S)--cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-3-methylbutyrate known under the name of esfenvalerate to deal with biting and sucking pests (Handbook of pesticides and agrochemicals permitted for use in the Russian Federation, M., 2000)

Insecticidal drug // 2176448
The invention relates to a means of combating harmful insects

Insecticidal drug // 2146090
The invention relates to a means of combating harmful insects, namely, to insecticide products based on pyrethroids, and reduces the toxicity to warm-blooded while maintaining high efficiency

The invention relates to the field of chemical agents against domestic insects

The invention relates to compositions for combating household insects

The invention relates to a process for the manufacture of chemical remedies against insects
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