Insecticidal gel-attractant

FIELD: medicine.

SUBSTANCE: he present innovation deals with eliminating harmful insects and ticks due to preparing poisoned attractants. As an active substance the suggested insecticidal gel-attractant contains chloropyriphos and a food foundation, additionally, it contains didecyldimethylammonium bromide of efficient amount being fused with chloropyriphos. The desirable content of didecyldimethylammonium bromide and chloropyriphos for eliminating cockroaches corresponds to 0.01-0.45%. Moreover, food foundation contains water, food attractant, water-retaining additive, gel-forming agent, emulsifier and conserving agent, additionally - hydrotropic additive and aromatizing agent. At the content of didecyldimethylammonium bromide and chloropyriphos being 0.01-0.3% it is useful to apply them to eliminate certain kinds of ants and wasps. Moreover, food foundation contains sorbitol, food attractant, gel-forming agent, emulsifying agent, oxidizing agent and conserving agent and, additionally, hydrotropic additive and aromatizing agent. The innovation is toxicologically safe and economical.

EFFECT: higher efficiency of desired result.

5 cl, 3 ex, 2 tbl

The invention relates to medical pest control, household chemicals and herbicides, in particular insecticidal preparations contact and stomach action, which may find application in medical practice pest control, agriculture, private farms and household for the destruction of harmful insects and mites through preparation of poison baits.

Known drugs contact and stomach action for the destruction of a wide range of harmful insects (beetles, bugs, plant-eating and blood-sucking ticks, flies, woodlice and other)that contains the HOUR of the formula [RR¹R²R³N]⁺X^-(where R-R³=alkyl, halogenated alkyl, alkenyl or the halogenated alkenyl and X = halogen), which have chemosterilant activity [1]. Amongst those listed in this patent a specific HOUR is dominated by iodides with allyl, 2-chlorallyl or 2-chlorobutadiene radical, which are the most active chemosterilants. Examples of their application are food bait in a sugar syrup with the addition of 1% allyltrimethylsilane [CH₂=SNSN₂N(CH₃)₃]⁺I^-or 0.5% 2-globalitemsneeded [CH₂=CClCH₂N(CH₃)₃]⁺I, effective against screwworm Cochliomya hominovorax. The shortcomings of such an HOUR unavailability in p is millennum scale, chemical nestability in the compositions and high toxicity for warm-blooded.

Known means of contact action to kill cockroaches and other household insects based on a synergistic combination of a PYRETHROID insecticide with lipophilic salts, benzalkonium and didecyldimethylammonium type [S₁₂H₂₅N(CH₃)₂CH₂With₆H₅]⁺X^-and [(C₁₀H_2l)₂N(CH₃)₂]⁺X^-(where X is the residue of stearic, saaristomeri, lauric or dodecylbenzensulfonate) [3]. The experimental data shown in this patent show that the claimed HOURS equivalent as synergists to the corresponding chlorides. Their disadvantages are weak synergistic effect (tested on cockroaches working emulsion contained 0.5% of tetramethrin in combination with a huge number of HOUR - 20%), the difficulty of obtaining and lack of industrial production.

Described insecticidal preparations for destroying termites and soil-inhabiting pests, containing combinations of didecyldimethylammoniumchloride, dioctyldimethylammonium or octylacrylamide with organophosphorus insecticides - fenitrothion or predatation [4]. These drugs are alcohol solution with a very high content of active components the clients (for example, 64% of didecyldimethylammoniumchloride, 5% fenitrothion and 31% of methanol), resulting in low efficiency and greater toxicity to warm-blooded.

Known means of contact steps to eliminate house dust mites, which contain the usual insectoacaracide (PYRETHROID, organophosphorus or other) in combination with an antiseptic that can kill bacteria and fungi that serve as food for the ticks [5]. In the example of the solution of 0.75% of cyhalothrin (a PYRETHROID of insectoacaracide) and 8% of benzylaniline with the addition of isothiazolinones in diethylene glycol. When applying this medication (without dilution) on the filter surface conditioning destruction dwell in them house dust mites was 94,66% after 1 hour and 100% in 2 hours. About synergy HOUR in this patent is not mentioned. The disadvantages of the above means, a narrow scope and a very high content of active ingredients, which accounts for its low cost and relatively greater toxicity to humans and domestic animals. In addition, diethylene glycol possesses narcotic properties, therefore to use it as part of a sawn drugs is undesirable.

Thus, from among the above HOURS only benzylaniline and didecyldimethylammonium the chloride, with less favorable price ratio: efficiency than traditional insecticides. In addition, benzylaniline always contains a mixture of chloride benzyl - substance tear smell, which makes it impossible to use in insecticidal food baits.

Known insecticidal gel preparations and methods for their preparation. (6, 7). These drugs are gels, including pretrade - Genotropin, allethrin. Obtaining gels based on the use of organic solvents, such as ethanol, isopropyl alcohol, n-organic.

The closest technical solution is insecticidal bait containing bait for insects, an effective amount of insecticide forming emulsion gel additives and other additives. As insecticide may be used chlorpyrifos, carbamates, pyrethroids (patent of the Russian Federation 96121385) (7). Industrial production of these lures is missing.

The technical result of the present invention is the creation of insecticidal gel bait that contains available on an industrial scale H in combination with conventional insecticides, improved efficiency in comparison with other known similar drugs beyond their economy and Toxicological safety.

The technical result dost is presumed to those what insecticidal gel bait, including technical chlorpyrifos and food basis, according to the invention as a food basics contains a food attractant, and optionally contains didecylammonium bromide or clathrate didecylammonium bromide with urea effective amount, fused with chlorpyrifos.

Preferably the content of didecyldimethylammoniumchloride and chlorpyrifos in the amount of from 0.01 to 0.45% for the extermination of cockroaches.

This insecticidal gel bait can optionally contain water, water-retaining additives, gelling, emulsifying agent and preservative.

For the destruction of house and garden ants and wasps preferably the content of didecyldimethylammonium or clathrate didecylammonium bromide with urea in an amount of 0.01 to 0.3%, chlorpyrifos in an amount of 0.01 to 0.3%.

When this gel bait can optionally contain sorbitol, gelling, emulsifying agent, an acidulant and preservative.

Insecticidal gel bait can optionally contain hydrotron additive and flavoring.

Used in the gel didecyldimethylammoniumchloride [(C₁₀H₂₁)₂N(CH₃)₂]⁺Br^-(DDAB) (RF patent 2155186, 27.08.00) can be applied in the form of the free compounds (chemically pure substance or product) or in the ideal of clathrates with urea [8, 9]. DDAB and clathrates are odorless, so you can use it in insecticidal food bait.

Due to the extremely high and varied antimicrobial activity DDAB offer us the means to destroy not only harmful insects and mites, but carried them pathogenic bacteria, fungi and viruses. This eliminates the need for special additional processing, which further increases the economic benefits from the use of the inventive preparations.

To date DDAB was known mainly as a component of such disinfectants as "Veltolen" (patent of the Russian Federation 2095086, 11.10.97), "Veltodez" (patent of the Russian Federation 2189834,27.09.02), "Veltolen-extra" (patent of the Russian Federation 2158142, 27.10.00).

Toxicity DCAB is approximately at the same level that didecyldimethylammoniumchloride and benzalconi-chloride, all of these HOURS and, especially, the clathrates DCAB less toxic to warm-blooded than traditional insecticides.

EXAMPLE 1. Insecticidal gel bait to kill cockroaches.

The method of obtaining the proposed gel to kill cockroaches osushestvlya in several stages. The first of them get active synergetic complex fusion 0,055% chlorpyrifos with 0,075% DTAB at a temperature of 45°C. Then add to it 0,87% emulsifier, a 3.5% hydrotropes additive and 0.1% flavoring.

Separate the dissolve about 30% water-retaining additives, 30% food attractant and 0.5% of a preservative in the water. Gradually add to this solution a mixture of the active complex with an emulsifier, hydrotropes additive and flavoring. Add 0.5% of gelling. The mixture is homogenized and get the next part.

Insecticidal gel bait to kill cockroaches.

Technical DCAB (considering 80%) of 0.075%

Technical chlorpyrifos (assuming 98%) to 0.055%

Emulsifier 0,87%

Girotropnye additive 3,5%

Gelling 0,5%

Food attractant 30%

Water-retaining additive 30%

Flavor 0,1%

Preservative 0,5%

Water to 100%

The chlorpyrifos is an organophosphorus insecticide [2], which is most often used in bait gels against cockroaches and ants, intended for use in medical disinfection and life. Usually the content is 0.5% (absolute-gel", "Oro-gel", "Global gel-paste", "Brownie-gel", "Zorro-gel", "Liquidator gel-paste", "Tornado-gel", "Fumitoks-gel", "Alphas" and others). Thanks to the powerful synergistic effect DCAB offer gel contains almost 10 times less than chlorpyrifos, making it cheaper than the known gels and much safer. In addition, it is effective against populations of cockroaches resistant to chlorpyrifos. This advantage is very important because of the widely what about the use of chlorpyrifos in medical practice pest control and household chemicals.

Technical chlorpyrifos - solid substance with a melting point of 41.5-44°C and technical DDAB - viscous semi-liquid mass. They both slowly soluble in all solvents. The fusion between them allows to get the active synergetic complex, adding to which an emulsifier and hydrotropes additives (ethanol or acetone) provides a uniform distribution in the amount of gel formation of a stable microemulsion. Flavor is introduced to improve the nutritional appeal of the gel.

Food attractant used in the third stage of the process necessary to disguise repellently chlorpyrifos and DAB. As it can be taken, for example, a mixture of dry dog food with sugar and beer mash. The hydrophilic additive is applied to slow the drying of the gel on the treated surfaces, as cockroaches prefer wet food. Such additive may serve as glucose, sorbitol, ▫ maltitol and other polyhydric alcohols. Preservative (sodium benzoate or sorbic acid) was injected to prevent microbial spoilage gel.

In the final stages of the process are added gelling (neutralized carbopol or sodium carboxymethyl cellulose) and produce homogenization of the finished recipe.

Food attractant and moisture add the and, gelling, emulsifier and preservative are mandatory components of the food basis of the gel, whereas hydrotron additive and flavouring can be omitted.

Insecticidal efficacy of gel on [11, method 3.4] compliance indicator [12] - the death of at least 70% after 48 hours (see table 1).

EXAMPLE 2. Insecticidal gel bait for the destruction of house and garden ants and wasps.

Technical DDAB (considering 80%) of 0.075%

Technical chlorpyrifos (assuming 98%) to 0.055%

Emulsifier 0,87%

Girotropnye additive 3,5%

Gelling 0,5%

Food attractant 40%

Flavor 0,1%

Acidifier 0,1%

Preservative 0,5%

Sorbitol to 100%

The method of obtaining the offered gel is carried out as in example 1. Instead of water is used sorbitol (70%sorbitol syrup), which dissolve food attractant, acidifier (buffer system with a pH 4-5) and preservative. These changes have been driven by the fact that ants and wasps love sweet food with high carbohydrate content. The use of sorbitol as a main component insecticidal food baits for ants known. Food attractant, gelling, emulsifying agent, an acidulant and preservative are mandatory components of the food basis of the gel, whereas hydrotron additive and flavouring can be omitted./p>

The results of the test gel according to the method 3.4 [11] are presented in table 2.

When field testing of the gel against the black garden ants was observed a complete disappearance of the day after pickup on the paths of movement of insects.

Among well-known commercial gels on chlorpyrifos listed in example 5, to destroy ants recommended "absolute-gel", "Brownie-gel", "Zorro-gel" and "Alphas". They all contain 0.5% chlorpyrifos, resulting in more expensive we offer gel and more toxic for warm-blooded.

This gel can also be used to destroy the OS, because they are close to the ants on the biology and taste preferences.

Example 3. Insecticidal gel bait to kill cockroaches.

The clathrate didecylammonium bromide

with urea 0,01%

Technical chlorpyrifos (assuming 98%) of 0.45%

Emulsifier 0,6%

Girotropnye the addition of 2.5%

Gelling 0,35%

Food attractant 35%

Water-retaining additive 45%

Flavor 0,15%

Preservative of 0.45%

Water to 100%

The method of obtaining the offered gel is carried out as in example 1.

Example 4. Insecticidal gel bait for the destruction of house and garden ants and wasps.

The clathrate didecylammonium bromide

with urea 0,3%

Technical chlorpyrifos (assuming 98%) 0,01%

E is Aligator 0,8%

Girotropnye additive 3%

Gelling 0,55%

Food attractant 30%

Flavor 0,1%

Acidifier 0,1%

Preservative 0,5%

Sorbitol to 100%

The method of obtaining the offered gel is carried out as in example 1.

Literature

1. U.S. patent 3397275, 13.08.68.

2. LNB, Kvinnoforum, Sreen. Pesticides and plant growth regulators. The Handbook. - M., "Chemistry", 1995.

3. The Japan patent 09-059109, 04.03.97.

4. The Japan patent 61-57506, 24.03.86.

5. Patent UK 2359023, 15.08.01.

6. RF patent 2077200, 20.04.1997.

7. The application for the patent of the Russian Federation 961211385, 27.01.2000.

8. Patent of Israel 58586, 30.10.79.

9. Patent Italy 1132629,02.07.86.

11. Methods of testing disinfectants for evaluation of their safety and efficacy. Decl. The health Ministry of the Russian Federation No. 01-12/75-97. - M., 1998, part 3.

12. Normative indicators of the safety and efficacy of disinfectants that are subject to control under the mandatory certification. Decl. The health Ministry of the Russian Federation No. 01-12/75-97.- M., 1998.

1. Insecticidal gel bait, including technical chlorpyrifos and food base, characterized in that as a food basics contains a food attractant, and optionally contains didecylammonium bromide or clathrate didecylammonium bromide with urea effective amount, fused with chlorpyrifos.

2. Insecticidal gel bait pop, characterized in that it contains didecyldimethylammonium or clathrate didecylammonium bromide with urea in an amount of 0.01-0.45% and the chlorpyrifos in the amount of from 0.01 to 0.45% for the extermination of cockroaches.

3. Insecticidal gel bait according to claim 2, characterized in that it further contains water, water-retaining additives, gelling, emulsifying agent and preservative.

4. Insecticidal gel bait according to claim 1, characterized in that it contains didecyldimethylammonium or clathrate didecylammonium bromide with urea in an amount of 0.01 to 0.3%, chlorpyrifos in an amount of 0.01 to 0.3% for the destruction of house and garden ants and wasps.

5. Insecticidal gel bait according to claim 4, characterized in that it further comprises sorbitol, gelling, emulsifying agent, an acidulant and preservative.

6. Insecticidal gel bait according to claim 3 or 5, characterized in that it contains additionally hydrotron additive and flavoring.