FIELD: veterinary sanitation.
SUBSTANCE: in the suggested disinfectant one should dissolve electrochemically activated neutral anolyte, containing 0.6 mg/ml active chlorine, with running water at 1:5 ratio and the composition of diluted electrochemically activated neutral anolyte should be supplemented with 1-1.5 mg acetic acid per 1 ml preparation. The innovation enables to decrease the concentration of active chlorine and energy expenses at keeping initial high bactericidal activity of electrochemically activated neutral anolyte and, also, apply it in aerosol form for air sanitation in poultry-breeding housings when poultry is present.
EFFECT: higher efficiency of disinfection.
The invention relates to veterinary sanitation, can be used in industrial and small-scale poultry farming as a disinfectant preparation for the renovation of the air of poultry houses in the presence of birds.
Known disinfection tool, including chlorinated compound and water (see kN.: A. A. Polyakov, "Veterinary disinfection", Moscow, Kolos, 1975, p.55-67).
However, the known tool has poisonous and sinnerschrader the mucous membranes of the respiratory tract and the eyes of the properties that makes it impossible for its use in aerosol form in the presence of birds.
It is also known chlorinated disinfection agent that is closest to the proposed invention in its essence and the achieved effect, consisting of electrochemically activated neutral anolyte, synthesized from a weak salt solution by setting type STEL (see kN.: "Electrochemical activation". Abstracts and short communications. Part I. Moscow, 1999, str-212).
The disadvantages of the known disinfectant is a high concentration of active chlorine is more than 0.6 mg/ml and significant energy consumption in its synthesis.
The purpose of the invention is the reduction of the concentration of active chlorine and power consumption while maintaining the original high bactericidal activity ele is trokhimenko activated neutral anolyte.
This objective is achieved in that the electrochemically activated neutral anolyte containing 0.6 mg/ml of active chlorine, diluted with tap water at a ratio of 1:5 and in the composition of the diluted electrochemically activated neutral anolyte impose 1-1 .5 mg of acetic acid per 1 ml of the drug.
In contrast to the known proposed disinfection agent is diluted with tap water at a ratio of 1:5 and in addition the composition of the diluted disinfectant is injected 1-1 .5 mg of acetic acid per 1 ml of the drug. Thus, the proposed disinfection agent meets the criterion of "novelty."
Following the distinction proposed disinfectant is that in dilute electrochemically activated neutral anolyte contains five times less active chlorine, or 0.12 mg/ml at a five-fold reduction of energy consumption for its synthesis, and additionally introduced as part of the preparation of acetic acid provides the preservation of the inherent undiluted electrochemically activated neutral anolyte high bactericidal activity that meets the criterion of "substantial differences".
The invention consists in that the electrochemically activated neutral anolyte containing 0.6 mg/ml of active PI is RA, diluted with tap water at a ratio of 1:5 and in the composition of the diluted electrochemically activated neutral anolyte impose 1-1 .5 mg of acetic acid per 1 ml of the drug. In comparison with known diluted with tap water electrochemically activated neutral anolyte contains 0,12 mg/ml of active chlorine, which is five times less than in undiluted neutral anolyte and aerosol spraying in the presence of birds is not marked irritation of the mucous membranes of the respiratory tract and eyes. The sputtering of neutral anolyte with a content of more than 0,12 mg/ml of active chlorine along with improved bactericidal activity irritates the mucous membranes of the respiratory tract and eyes.
While the introduction of the diluted neutral anolyte 1 mg of acetic acid per 1 ml of the drug provides 100%mortality of Escherichia coli and Staphylococcus aureus in suspension experiments in contact for 10 minutes In the case of injection of 1.5 mg of acetic acid per 1 ml 100%death of microorganisms is achieved when the contact within 2 minutes
The proposed disinfection tool, while maintaining high bactericidal activity, aerosol spray is not irritating to the mucous membranes of the respiratory tract and eyes, reduced saving the cost of electrochemical activation of salt solutions what is a "positive effect".
In known disinfection tool contains more than 0.6 mg/ml of active chlorine and its application in aerosol form in the presence of birds is accompanied by irritation of the mucous membranes of the respiratory tract and eyes. While preparing the requested amount of electrochemically activated chlorine neutral anolyte is associated with a fivefold increase in energy consumption.
The results of the bactericidal activity of the proposed disinfectant listed in table 1.
|The bactericidal activity of neutral anolyte with different content of active chlorine and combined with acetic acid|
|The research object||Control||The growth of bacteria after treatment (exposure time 2 min)|
|Neutral anolyte (CAH) 0.6 mg/ml||Neutral anolyte (CAH) of 0.12 mg/ml||Acetic acid in combination with a neutral anolyte (CAH) of 0.12 mg/ml) at the rate of 1.5 mg/ml||Acetic acid in distilled water at the rate of 1.5 mg/ml|
|.li||104||no growth||480||no growth||102,9|
|St.aureus||104||no growth||42||no growth||103,0|
|Note: (Kah) - the concentration of active chlorine|
As can be seen from table 1, the neutral analyte with a content of active chlorine of 0.12 mg/ml in combination with acetic acid at the rate of 1.5 mg per 1 ml of neutral anolyte provides 100%disinfection of suspensions of microorganisms in contact within 2 minutes there synergenic effect, i.e. stronger antimicrobial activity compared with the effect of each drug alone. At neutral anolyte with the content of 0.12 mg/ml of active chlorine death of bacteria is 95-96%, and when the action of a solution of acetic acid in distilled water with a content of 1.5 mg/ml dying bacteria is 10-12%. The use of acetic acid in combination with a neutral anolyte effect of antimicrobial action increases and the death of microorganisms reaches 100%.
From table 1 it is evident that 100%death of microorganisms is observed when the concentration of active chlorine in neutral anolyte 0.6 mg/ml
Audit trail the way: in suspension in a sterile test tubes contribute to 9 ml of the test solution and 1 ml of 1 billion mist sanitary-indicative microorganisms: .oli or Staph.aureus. After exposure through 2, 5, 10 min from the tubes take 1 ml of the mixture and transferred into a test tube with 6 ml of sterile saline solution, and shake, and after 1-2 minutes doing the sowing of 0.6 ml liquid IPA in Petri dishes. The latter is placed in a thermostat at 37°and incubated for 24-72 hours. Accounting bactericidal activity is performed according to the number of grown colonies of microorganisms on MPA in Petri dishes.
Disinfection means for processing premises in the presence of birds, including the electrochemically activated neutral anolyte with the content of 0.6 mg/ml of active chlorine, wherein it is diluted with tap water at a ratio of 1:5 and to preserve the original high bactericidal activity of the composition diluted electrochemically activated neutral anolyte impose 1-1 .5 mg of acetic acid per 1 ml of the drug.
SUBSTANCE: means comprises amber acid and/or its salts, fructose, dry extraction of Saint John's wort, magnesium ion sources, potassium ion sources as active bases and auxiliary substances, carriers and/or fillers when needed.
EFFECT: enhanced effectiveness of treatment.
4 cl, 4 tbl
FIELD: experimental medicine.
SUBSTANCE: on should introduce solution into fracture area at the following ratio of ingredients, g/l: 1-hydroxyethylidenediphosphonic acid 1.80 - 2.06, water-free calcium chloride 1.44 - 2.22, gadolinium (III) nitrate hexahydrate 0.30 - 0.40, dysprosium (III) chloride hexahydrate 0.038 - 0.076, moreover, solution's pH corresponds to 7.3 - 7.8. The present innovation enables to shorten the process of bony tissue regeneration in the site of its lesion or defect and, also, shorten the period for restoring normal physiological function of traumatized bone.
EFFECT: higher efficiency of regeneration.
22 ex, 1 tbl
SUBSTANCE: method involves introducing cauterizing necrotizing composition like paste containing silver nitrate and dextrane into uterine cavity. Paste contact to target tissue is supported during time enough for reaching chemical necrosis. Then cauterizing composition is brought in contact with deactivating agent like aqueous solution of sodium chloride and removed from the uterine cavity later on. It is proposed to protect non-target tissue by supplying protection agent to it and carrying out previously described steps.
EFFECT: enhanced effectiveness of cauterization controlled in time and action intensity degree; avoided other tissue injuries.
30 cl, 8 dwg
FIELD: polymer materials in medicine.
SUBSTANCE: aqueous solution according to invention contains 0.05-0.11 mole/L oxalic acid and 0.02-0.17 mole/L alkali metal salt(s). Treatment of polymethylmethacrylate materials with such solution allows complete removal of residual monomer without alteration of molecular mass and supramolecular structure of polymer material.
EFFECT: reduced risk of rejection of implants and improved mechanical and optical properties thereof.
1 tbl, 3 ex
FIELD: animal science, veterinary science.
SUBSTANCE: the suggested composition for disinfecting objects of animal science includes dispersion dyestuff and active substance as conservant-disinfectant FH and, additionally, cationic surface active substance at certain quantitative ratios of components. Moreover, disinfecting composition contains either alkyldimethylbenzylammonium chloride, or cetylpiridinium chloride or hexidine chloride as cationic surface active substance. This innovation provides increased terms of residual biocidal (bactericidal and fungicidal) activity.
EFFECT: higher efficiency of disinfection.
1 cl, 11 ex
FIELD: animal science, veterinary science.
SUBSTANCE: the suggested composition includes either chalk or slaked lime, additionally, it may contain conservant-disinfectant FX at certain ratios of components. The innovation provides increased terms of residual biocidal (bactericidal and fungicidal) activity.
EFFECT: higher efficiency of disinfection.
SUBSTANCE: method involves puncturing pyogenic abscess cavity under ultrasonic control with draining tube left therein. Laparoscope connected to monitor unit is introduced into abscess cavity. One of introduced drains is set in upper point of the cavity and the other one in lower point. The abscess cavity is filled with ozonized solution to 2/3 of its volume and bubbled with ozone-oxygen mixture during 2-3 min changing the solution until it becomes transparent. The emptied cavity walls are treated from distance of 3-4 cm with laminar airflow heated to 38-40°C under pressure of 1-1.5 atm during 2-3 min. Next to it, the cavity walls are irradiated from distance of 2-3 cm with non-coherent red light during 2-3 min per each area.
EFFECT: improved safety conditions and healing quality.
FIELD: medicine, pulmonology.
SUBSTANCE: one should perform lovage in three stages:during the 1st stage one should carry out lovage of tracheoalveolar tree for 3-4 min with 60-80 ml 0.08%-sodium hypochlorite solution, at the 2nd stage one should introduce 5-7 ml 10%-fluimucyl solution into tracheobronchial tree for 4-6 min, and at the 3d stage one should perform lovage of tracheobronchial tree for 3-4 min with 60-80 ml 0.11%-sodium hypochlorite solution. The present innovation favors secreta release of decreased viscosity into large bronchi that simplifies its evacuation and this, in its turn, simplifies the access of antiphlogistic and antibacterial preparations towards tracheobronchial tree's mucosa that leads to interrupting inflammatory process in more shortened terms.
EFFECT: more prolonged period of remission.
FIELD: medicine, obstetrics, gynecology.
SUBSTANCE: rehabilitation should be carried out in the third trimester of pregnancy based upon dispensary situated in ecologically safe region, as an enterosorbent one should apply "Carbopect" preparation per 0.5-0.6 g once daily for 3 wk; as an iodine preparation it is necessary to prescribe "Potassium iodide" 200 mcg once daily till the end of pregnancy period and during the whole period of lactation; as adaptogens one should additionally prescribe "Revit" per 2 lozenges thrice daily for 2 wk; vitamin-containing tea; one should, also, apply aerotherapy named "mountain air" per 15-40 min, 15 procedures, totally. The present innovation enables to improve anthropometric parameters in neonatals, decrease the percentage of complications in babies in early neonatal period, among them those that require antibioticotherapy.
EFFECT: higher efficiency of rehabilitation.
SUBSTANCE: the present innovation deals with antiviral preparations that contain aliphatic alcohol C21-C28 in combination with either nucleoside or nucleotide analog or phosphoformic acid in pharmaceutically acceptable carrier. It is necessary to mention that n-docosanol is considered to be a preferable aliphatic alcohol. Concentration of aliphatic alcohol C21-C28 corresponds to 0.05% to 40% by weight. Concentration of either nucleoside or nucleotide analog or phosphoformic acid corresponds to 0.1% to 10% by weight. The innovation, also, deals with the ways to treat viral infections due to applying such compositions. Aliphatic alcohols C21-C28 synergistically intensify antiviral activity of nucleoside analogs directed against replication of several herpetic viruses and that of cow's pox.
EFFECT: higher efficiency of inhibition.
28 cl, 13 dwg, 21 ex, 6 tbl