Composition and method for controlling hair excretion with feces and preventing from trichobezoar formation

FIELD: veterinary medicine.

SUBSTANCE: composition comprises raw protein 10 to 42% by mass, fat 4 to 30% by mass, total dietetic cellular tissue 1to 25% by mass and source of additional nutrient fibers. Method involves keeping animals on the like dietary intake during time required for controlling hair excretion with feces and preventing from trichobezoar formation.

EFFECT: enhanced effectiveness of prophylaxis and treatment.

22 cl, 12 tbl

 

The present invention relates to a method and composition for regulating the excretion of faeces wool and prevent the formation of trichobezoar animals, such as cats and rabbits, which can be formed in the gastrointestinal tract concretions containing wool.

Animals that constantly lick themselves, such as cats and rabbits, systematically swallow a large quantity of wool. Usually swallowed the wool passes through the gastrointestinal tract of the animal and is excreted in the feces. However, the ingestion of large quantities of wool can lead to its accumulation in the stomach and the formation of conglomerate in the intestine, containing wool, or trichobezoar. Trichobezoar usually consists of wool, mucus, water, non-digested food particles and mineral salts. Such hair concrements can be detrimental to an animal's body, if he interferes with the normal digestive process, blocking the pylorus is preserved and preventing the passage of food mass down the gastrointestinal tract. In the more frequent cases, trichobezoar - not that other as an object, nuisance animal and its owner. For example, the cat usually tries to remove the hairball from the stomach, causing a gag reflex. Trichobezoar can cause constipation and difficulty urinating, if the wool passes from the stomach and is delayed in the lower division to what Chechnya.

Trichobezoar hitherto treated using jelly vaseline, mineral oil and other laxatives contained in various forms as a component of diet and/or dietary supplements.

The effectiveness of laxatives of this type to prevent the formation of trichobezoar in the best case was the magnitude of the variable. An alternative strategy, which was made to prevent the formation and appearance of the hair concretions, involves the use of diets or dietary supplements with a high content of indigestible (insoluble) fiber, such as cellulose, which ensures an increase in passage of the wool through the gastro-intestinal tract with the release of her stool, without causing the phenomenon of intestinal obstruction or constipation. However, these diets can reduce the quality of the chair, to cause diarrhea, but otherwise they do not contribute to the restoration of normal functioning of the digestive tract.

Although in animal diets do not require supplements of fiber, studies have shown that moderate amounts formatiruem fibers in the diet of animals help maintain normal functioning of the gastrointestinal tract. Depending on the specific composition and physical properties of di the optical fiber usually increases the water holding capacity, regulates the emptying of the content coming from the stomach, increases the transit time of food through the intestines and supports the structural integrity of the intestinal mucosa. However, the presence in the diet of large quantities of vysokogermetichnyh fibers typically reduces the digestibility of dry matter, protein and lipids, and can lead to the formation of a diarrhea-like stool, especially when fed a diet of cats (see G.D. Sunvold and other "Dietary fiber for cats: In vitro fermentation of selected sources of plant fiber inoculate faeces of cats and the use of in vivo diets containing selected sources of fibers and their mixtures", J.Anim. Sci. (1995) VIP: str-2339. In cats fed large quantities of sources of insoluble fiber, also noted other unwanted side effects such as constipation, excessive output of the chair, lowered the digestibility of nutrients and the emergence of undercoat.

Studies using in the diet sources moderately formatiruem (digestible) fibers such as beet pulp, fructo-oligosaccharides (FOS), citrus pulp and gum Arabic showed that they increase the production of short-chain fatty acids, the proliferation of colonocytes, improve the quality of skin and hair coat and consistency of feces (with whom. the work of G.D. Sunvold and the others mentioned above; Drackley J.. and other Energy substrates for the intestinal cells,"; Reinhart G.. and Carey D.P., eds.," Recent advances in the nutrition of dogs and cats: volume 2, 1998; Iams Nutrition Symposium Proceedings, Wilmington, OH: Orange Frazer Press, str-472, 1998; Kelley, R. and others," the Effect of sugar beet pulp on the digestibility of nutrients in cats", J. Anim. Sci, VIP (see App. 1): str, 1998. However, the influence of sources moderately digestible fibers on the education of trichobezoar and selection of wool with stool up to the present time have not been studied.

In accordance with the above, in the art there is a need to create a method and composition for regulating the allocation of hair with faeces and education trichobezoar animals, such as cats and rabbits, which would be effective and not have the disadvantages of the known technical solutions.

The present invention satisfies this need by creating a method and composition for regulating the allocation of wool with faeces and prevent the formation of trichobezoar animals, such as cats and rabbits, which would be effective and contributed to the normalization of the functioning of the gastrointestinal tract and did not cause other gastrointestinal problems.

In accordance with one variant of the present invention proposes a method for regulating the allocation W is tifa from faeces and prevent the formation of trichobezoar animals namely, that it involves feeding the animal a composition containing from 10 to 42 wt.% crude protein, from 4 to 30 wt.% fat, from 1 to 25 wt.% total dietary fiber and a source of additional dietary fiber.

The source of additional dietary fiber is preferably selected from the group consisting of at least one fermentive fibres; mixtures consisting of at least two formatiruem fibres; mixtures consisting of at least one fermentive fiber and simple cellulose ether; mixtures consisting of at least one fermentive fiber, simple cellulose ether and mineral oil; and mixtures comprising at least one fermentive fiber and at least one nonfermentable fiber. The source of additional dietary fiber is preferably contained in an amount which provides from 1 to 13 wt.% additional General dietary fiber, more preferably from 6 to 12 wt.%, and most preferably from 10 to 12 wt.%.

Under used in this application, the term "fermentive fiber" should be understood sources of fibers, which are an indicator of digestibility of organic substances from 15 to 100% during the fermentation of their fecal bacteria within 24 hours. In the preferred embodiment, used in feeding status is ve feed of the present invention formatiruem fibers have an index of digestibility of organic matter at least 20%. Formatiruem fibers are preferably selected from the group consisting of beet pulp, gum Arabic, fructo-oligosaccharides and mixtures thereof.

Under used in this application, the term "nonfermentable fiber" should be understood sources of dietary fiber, which are an indicator of digestibility of organic matter less than 15% during the fermentation of their fecal bacteria within 24 hours.

In one embodiment of the invention a source of additional dietary fiber contains a blend of beet pulp and carboxymethylcellulose. In another embodiment of the invention a source of additional dietary fiber contains a blend of beet pulp, carboxymethylcellulose and mineral oil. In another embodiment of the invention a source of additional dietary fiber contains a blend of beet pulp and cellulose.

In the following embodiment of the invention a source of additional dietary fiber contains 6 wt.% beet pulp, 2.0 wt.% gum Arabic and 1.5 wt.% of fructo-oligosaccharides. In another embodiment of the invention a source of additional dietary fiber contains 6 wt.% beet pulp and 1.5 wt.% carboxymethylcellulose. In the following embodiment of the invention a source of additional dietary fiber with the contains 6 wt.% beet pulp, 1.5 wt.% carboxymethyl cellulose and 2 wt.% mineral oils. In another embodiment of the invention a source of additional dietary fiber contains 6 wt.% beet pulp and 6.5 wt.% the pulp. In another embodiment of the invention a source of additional dietary fiber contains 12 wt.% beet pulp.

The animal contain the specified diet for a period of time sufficient to regulate the allocation of wool with faeces and prevent the formation of trichobezoar.

Thus, a feature of the present invention is a method and composition for regulating the allocation of hair with faeces and prevent the formation of trichobezoar animals, such as cats and rabbits, which would be effective and contributed to the normalization of the functioning of the gastrointestinal tract and did not cause other gastrointestinal problems.

These and other features and advantages of the present invention will become apparent from the following detailed description and the accompanying claims.

In the scope of the present invention features a composition that, when fed to animals such as a cat or rabbit, is prone to the formation of trichobezoar, effectively prevents the formation of hair concretions and regulates the allocation of wool with feces, this contributes to normal is the functioning of the gastrointestinal tract of the animal. The present invention offers an improvement known in the field of methods of treatment of trichobezoars, for example, using pineapple juice, hay, vaseline and mineral oil, which exert their effects either by dissolving part of the protein of the hair calculus, or by transit wool through the intestines. The present invention not only provides an effective way to remove lumps of wool from the gastrointestinal tract of the animal, but also contributes to its normalization due to the introduction in the diet of the animal formatiruem fibers that can form short-chain fatty acids, which, in turn, contribute to the normal functioning of the epithelium of the colon and the change in the composition of the intestinal microflora.

In used in the present invention formatiruem the fiber digestibility of organic matter (DOM) during fermentation in vitro fecal bacteria within 24 hours is 15 to 100%. This means that fermentation and transformations of fecal bacteria is exposed from 15 to 100% of the original total amount of organic substances. Preferably, the indicator SURFACE of these fibers was at least 20%, and most preferably at least 30%.

Thus, % digestibility of organic matter (DOM) in vitro can be calculated by either sleduyushei the formula:

{1-[rest OB-OB control)/original present S]}×100,

where the remainder of the OB - is an organic substance found after 24 hours of fermentation, OB in control - organic matter found in the respective test tubes (tubes filled with medium and diluted feces and containing no substrate), and the source is present OB - organic matter placed in the tube before fermentation. Additional details of this procedure are given in the work: Sunvold and others, J. Anim. Sci., 1995, Tom: str-1109.

Formatiruem fiber used in the present invention, lead to the formation of short-chain fatty acids (CCGC) in an amount of from ≈ 28 to ≈85 mmol CCGC per 1000 kcal transformed in the course of metabolic energy (OE), more preferably from ≈42 ≈71 mmol CCCG per 1000 kcal MA. This is equivalent to such a composition, the total content of which formatiruem fibers for every kilogram of food network ≈100 to ≈350 mmol CCCG.

The number CCCG (mmol)per 1000 kcal MA, determined at the first stage, calculating the total number of kilocalories MA in this dietary intake per kilogram of composition. Based on this first calculation, you can get the number of grams per 1000 kcal MA. Then you can calculate the number of grams, (and sledovat is Ino, and the mmol), components formatiruem fibers of the specified structure.

As formatiruem fibers may be any source of fiber, which can ferentiates by bacteria in the intestines of animals, with the possibility of producing significant quantities of short-chain fatty acids (CCGC).

"A significant number" CCGC for the purposes of this invention means the amount of more than 0.5 mmol total number CCGC/g of substrate per 24-hour period. As the preferred sources of dietary fiber can serve as beet pulp, gum Arabic, gum of Talhi, rice bran, gum beans, carob, citrus pulp, citrus pectin, fructo-oligosaccharides, mannanoligosaccharide and mixtures of these fibers.

Formatiruem fibers can also be mixed with other sources of not digested fibers, such as cellulose and ethers of cellulose, or laxative, such as jelly-like petrolatum or mineral oil. In a preferred embodiment of the invention formatiruem dietary fiber selected from the troupe, consisting of beet pulp, gum Arabic, fructo-oligosaccharides and mixtures thereof.

In the preferred embodiment, as a mixture consisting of at least one fermentive fiber and simple ether CE is lulzy can be a mixture of beet pulp and carboxymethylcellulose. Preferably, as a mixture consisting of at least one fermentive fiber, simple cellulose ether, mineral oil used a mixture consisting of beet pulp, carboxymethylcellulose and mineral oil. The preferred mixture consisting of at least one fermentive fiber and at least one nonfermentable fiber, may be a blend of beet pulp and cellulose.

In the most preferred embodiment, the source of additional dietary fiber selected from the group of cellulose of the following composition: 6 wt.% beet pulp, 2.0 wt.% gum Arabic, 1.5 wt.% the fructo-oligosaccharides; 6 wt.% beet pulp and 1.5 wt.% carboxymethylcellulose; 6 wt.% beet pulp, 1.5 wt.% carboxymethyl cellulose and 2 wt.% mineral oil; 6 wt.% beet pulp and 6.5 wt.% cellulose; and 12 wt.% beet pulp. Formatiruem fibers used in the composition of pet food in quantities which range from 1 to 13 wt.% additional General dietary fiber, preferably from 6 to 12 wt.% and most preferably from 10 to 12 wt.%.

The term "supplemental total dietary fiber" first requires the clarification of the term "total dietary fiber". "Total dietary fiber" is defined as the balance of food prod the KTA plant origin, which is not subjected to hydrolysis by the digestive enzymes of the animal. The main components of total dietary fiber are cellulose, hemicellulose, pectin, lignin and resin (as opposed to crude fat, which contains only some forms of cellulose and lignin). "More total dietary fiber" means such of dietary fiber, which is added to any food product above and beyond any dietary fiber, present in the natural state other components of the food product. In addition, under "source of fiber" refers to such, if it mainly consists of (fiber).

The animal is preferably fed ration containing from 10 to 42 wt.% crude protein, from 4 to 30 wt.% fat, from 1 to 25 wt.% total dietary fiber, with the introduction from 1 to 13 wt.% additional General dietary fiber, as described above. In the diet may also be present the vitamins, minerals and nutrients.

Using sources formatiruem fibers, as it turns out, has a favorable effect on the prevention of the formation of hair concretions (trichobezoars) by accelerating the passage of swallowed wool along the gastro-intestinal tract and its subsequent excretion in the faeces of the animal. Not wanting ogran is to rise by any specific theory, I believe that the increase in the rate of passage and excretion of faeces reduces the possibility of accumulation of wool in the gastrointestinal tract of the animal and the education of trichobezoars. Thus, suppose that the adhesive source of dietary fiber, for example fermentive fiber in pure form or in mixture with other dietary fibers, captures and binds swallowed wool with food particles. The high content in dietary fiber improves the emptying of stomach contents, resulting in more frequent selection of wool through the feces. I believe that this acceleration of passage of food mass reduces the accumulation of fur in the stomach and the risk of chronic trichobezoars disease. Another beneficial effect of the use of source formatiruem fibers is to improve the overall digestibility by providing adequate time for the digestive process, thereby preventing the occurrence of conditions associated with lack of nutrients. In contrast, the use of insoluble fiber as the sole source of fiber in the diet of cats can cause adverse effects on the digestibility of nutrients and the quality of the chair and also adversely affect the condition of the skin and hair coat when fed she is on diet for an extended period of time.

For a better understanding of the essence of this invention are the following examples serve only to illustrate and not limit its scope.

Example 1

Several diet compositions were examined to assess their impact on the allocation of wool animal faeces and effect on the prevention of the formation of trichobezoar in the gastrointestinal tract. Assess the potential effectiveness of sources of dietary fiber for preventing the formation of trichobezoar in the gastrointestinal tract was performed on the basis of the results of the assessment of the degree of removal of wool from faeces and indicator molting fur. Sources of fibers was evaluated by introducing them to a variety of basic diet recipes containing chicken meat, flour from wastes of poultry, corn flour, flour from grain sorghum, dried egg powder, fish meal, poultry fat, vitamins and minerals. Evaluated the effectiveness of diets with the addition of the following sources of fibers and/or mixtures thereof: (1) 6 wt.% beet pulp 2.0 wt.% gum Arabic and 1.5 wt.% the fructo-oligosaccharides (FOS); (2) 6 wt.% beet pulp and 1.5 wt.% carboxymethylcellulose; (3) 6 wt.% beet pulp, 1.5 wt.% carboxymethyl cellulose and 2 wt.% mineral oil; (4) 6 wt.% beet pulp and 6.5% cellulose; and (5) 12% beet pulp. Group rations that use is arranged as a control for comparison of results, included: main diet food with the addition of 13 wt.% cellulose as a source of fibers and commercially available feed composition containing about 4 wt.% beet pulp.

These five experimental and two control diets were evaluated over a 10-week study period on the basis of the results obtained when feeding their 80 cats. The study consisted of a 6-week baseline period and 4-week experimental period. In the base period, all cats were fed commercially available feed composition for cats to establish baseline rates of loss of wool and the rate of release of hair for each individual cat. Initial data used for the separation of cats in groups of eight food rations for standardization of indicators of loss of wool and selection of wool with faeces obtained in all eight rations. The criteria used to evaluate the effectiveness of various sources of fibers and/or mixtures, based on a subjective point quality assessment chair (score of 4.0 was considered ideal), the rate of loss of wool, the indicator of fecal wet, the moisture content of the stool, the rate of stool in the dry state and the daily output of wool with the feces.

Fecal allocated by cat, on a weekly basis of going to and throughout the study to assess the content of the wool. A composite sample of faeces collected during the week each cat, dried by sublimation and grinded before separating for the quantitative assessment of each component of the coat using a series of sieves and method mechanical screening. The molting rate was established for each cat by collecting and weighing wool when used standardized methodology tangle free animal brush.

The results are given in the following Tables 1-6. As can be seen from Table 2, cats consuming the ration No. 3, showed a significant reduction in the loss of hair on 4 a week.

Table 1

Subjective ball quality assessment chair
(1 - liquid, watery, 2 = liquid, gelatinous; 3 = paleovalley; 4 = decorated; 5 = hard, dry
DietThe source fibersThe source dataWeek 1Week 2Week 3Week 4
16% Beet pulp, 2% gum Arabic, 1.5% FOS4,224,033,974,103,86
26% Beet pulp, 1.5% carboxymethyl-cellulose3,893,623,49to 3.67
36% Beet pulp, 1.5% carboxymethyl-cellulose, 2% mineral oil4,344,144,274,214,13
46% Beet pulp, 6.5% cellulose4,434,594,574,57with 4.64
512% Beet pulp4,344,494,484,484,60
613% Celluloseor 4.314,574,554,594,55
7Commercial feed composition for cats4,343,90as 4.024.09 to4,21

Table 2

Figure molting fur (the number of wool collected after brushing, grams )
DietThe source fiberThe source dataWeek 4Time Effect (P<)
16% Beet pulp, 2% gum Arabic, 1.5% FOS,56,41
26% Swallowin the second slurry, 1.5% carboxymethylcellulose,44,42
36% Beet pulp, 1.5% carboxymethyl cellulose, 2% mineral oil,53x,25x,05
46% Beet pulp, 6.5% cellulose,39,28
512% Beet pulp,58,46
613% Cellulose,40,36
7Commercial feed composition for cats,31,27
The effectiveness of the diet (P<)NS
NS - not significant

Example 2

A second study conducted by the same method described in Example 1 with respect to the mixture of fibres, containing 6% beet pulp and 6% cellulose, which was added to the basic diet food containing chicken meat, flour from waste poultry, corn flour, mucus grain sorghum, egg product, fish meal, poultry fat, vitamins and mineral elements. Commercially available composition of feed for cats with the addition of about 4 % sugar beet pulp was included in the study for comparative purposes.

The results can be seen below in Tables 7-12.

As you can see, cats consuming the diet containing 6% beet pulp and 6% cellulose, showed an increase in the content of selected wool.

Although illustrated and described above specific embodiments of the present invention and its parts, specialists in this field are obvious, various modifications of the methods disclosed here, not going beyond the beings of the present invention and scope of the following claims.

1. The composition for regulating the allocation of wool with faeces and prevent the formation of trichobezoar the animal containing 10-42 wt.% crude protein, 4-30 wt.% fat, 1-25 wt.% total dietary fiber and additional General dietary fiber, containing a source of additional dietary fiber.

2. The composition according to claim 1, wherein said additional source is isiugo fiber is present in a quantity which is 1-13 wt.% from a more General dietary fiber.

3. The composition according to claim 1, wherein said source of additional dietary fiber is present in an amount which is 6 to 12 wt.% from a more General dietary fiber.

4. The composition according to claim 1, wherein said source of additional dietary fiber is present in an amount which is 10-12 wt.% from a more General dietary fiber.

5. The composition according to claim 1, wherein said source of additional dietary fiber selected from the group consisting of at least one fermentive fibres; mixtures consisting of at least two formatiruem fibres; mixtures consisting of at least one fermentive fiber and simple cellulose ether; mixtures consisting of at least one fermentive fiber, simple cellulose ether and mineral oil; and mixtures comprising at least one fermentive fiber and at least one nonfermentable fiber.

6. The composition according to claim 1, wherein said source of additional dietary fiber contains a blend of beet pulp and carboxymethylcellulose.

7. The composition according to claim 1, wherein said source of additional dietary fiber contains a blend of beet pulp, carboxymetilcellulose and mineral oil.

8. The composition according to claim 1, wherein said source of additional dietary fiber contains a blend of beet pulp and cellulose.

9. The composition according to claim 1, wherein said source of additional dietary fiber contains 6 wt.% beet pulp, 2.0 wt.% gum Arabic and 1.5 wt.% of fructo-oligosaccharides.

10. The composition according to claim 1, wherein said source of additional dietary fiber contains 6 wt.% beet pulp and 1.5 wt.% carboxymethylcellulose.

11. The composition according to claim 1, wherein said source of additional dietary fiber contains 6 wt.% beet pulp, 1.5 wt.% carboxymethyl cellulose and 2 wt.% mineral oils.

12. The composition according to claim 1, wherein said source of additional dietary fiber contains 6 wt.% beet pulp and 6.5 wt.% the pulp.

13. The composition according to claim 1, wherein said source of additional dietary fiber contains 12 wt.% beet pulp.

14. The composition according to claim 5, in which these formatiruem fibers are selected from the group consisting of beet pulp, gum Arabic, fructo-oligosaccharides and mixtures thereof.

15. The composition according to claim 5, in which these formatiruem fibers have an index of digestibility of organic matter at least 20%.

16. The method of regulating the allocation of wool with faeces and prevent the formation of trichobezoar the animal is about, namely, that the animal feed composition containing 10-42 wt.% crude protein, 4-30 wt.% fat, 1-25 wt.% total dietary fiber and additional General dietary fiber, containing a source of additional dietary fiber.

17. The method according to item 16, wherein said source of additional dietary fiber is present in an amount which is 1-13 wt.% from a more General dietary fiber.

18. The method according to item 16, wherein said source of additional dietary fiber selected from the group consisting of at least one fermentive fibres; mixtures consisting of at least two formatiruem fibres; mixtures consisting of at least one fermentive fiber and simple cellulose ether; mixtures consisting of at least one fermentive fiber, simple cellulose ether and mineral oil; and mixtures comprising at least one fermentive fiber and at least one nonfermentable fiber.

19. The method according to item 16, wherein said source of additional dietary fiber contains a blend of beet pulp and carboxymethylcellulose.

20. The method according to item 16, wherein said source of additional dietary fiber contains a blend of beet pulp, carboxymethylcellulose and mineral is of asle.

21. The method according to item 16, wherein said source of additional dietary fiber contains a blend of beet pulp and cellulose.

22. The method according to p in which these formatiruem fibers are selected from the group consisting of beet pulp, gum Arabic, fructo-oligosaccharides and mixtures thereof.



 

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