Method and device for recording pulse wave

FIELD: medicine; medical engineering.

SUBSTANCE: method involves irradiating blood-carrying tissue area under control with luminous flow, receiving scattered luminous flow modulated with blood filling changes in blood vessels and capillaries of blood-carrying tissue and forming electric signal of pulse wave. Deviation signal of light-emitting and light-receiving transducers of optoelectronic converter relative to blood-carrying tissue area under control based on difference between the current and preceding values of impedance signal on the area under control. The signal being observed, prohibition signal is produced on pulse wave electric signal passage for excluding errors caused by motion artifacts from its following processing. The device has optoelectronic converter having light-emitting and light-receiving transducers and unit for producing pulse wave signal, which input is connected to light-receiving transducer output. Unit for forming deviation signal has two measuring electrodes connected to separate comparator inputs which output being deviation signal former output, is connected to control input of key. Information input of the key is connected to pulse wave signal former output.

EFFECT: improved noise immunity.

3 cl, 3 dwg

 

The invention relates to medical equipment, namely to the means of reception signal of the pulse wave using the measurement of changes in optical density of cruisesusa tissue or its reflectivity. The invention can be used to estimate the parameters of the heart rhythm, in particular heart rate.

Known methods and devices for reception of the pulse wave using the changes in optical density of graveness tissues under the influence of the cardiac emissions blood vessels and capillaries cruisesusa tissue. For successful registration of cardiac activity, in particular peripheral pulse in such adverse conditions, such as ambient light, cold hands or thin fingers - designed circuit solutions, providing support to record cardiac activity. However, the main problem of these methods of registration is in electrical cardiac activity signal interference from motion artifacts. On the output electrical signal of the pulse wave is affected not only by optical modulation of the light flux in cruisesusa tissue, but also a hindrance associated with modulation of the light flux from involuntary displacement sensors optoelectronic Converter controlled stretch of cruisesusa tissue. Ledue is to be noted, that the spectra of the noise and signal can be the same. Therefore, various signal processing techniques, for example, the scheme of signal processing with nonlinear integrator (SU 0603372, IPC And 61 In 5/024, 1978), increased selectivity plethysmographic sensor by narrowing the frequency band of the analyzed signal (EN 93058039 AND, IPC And 61 In 5/0245, 1993), only slightly reduce the noise level, which remain in the electrical signal of the pulse wave and from further analysis of this signal. When determining the heart rate, and this is the task that often decide, you must have the electrical signal of the pulse wave, free from interference from motion artifacts.

Closest to the technical essence and the achieved result is the analogue of the invention adopted for the prototype, is a way to check the pulse wave (EN 2135076 C1 IPC And 61 In 5/024, 1998), in which the irradiated area cruisesusa tissue luminous flux, taking the scattered light flux modulated by the change of the blood in the vessels and capillaries in cruisesusa tissue and form an electrical signal of the pulse wave. For suppression of motion artifacts record the current value of the output electrical signal into a sequence of digital samples in increments of not less than 10 in 1 C. Of the obtained sequences are used to indicate the reference pulse is tion, later in the analysis mode on the current step, select the plot duration 1-3 with and established criteria define the start and end points of single pulses, calculates the correlation coefficient between the reference and referred to a single pulse. Determine the amplitude of the above-mentioned ripple and noise variance, however, in the case of coincidence with the above criteria, the conclusion about the presence of physiological pulsations caused by the movement of blood.

The device for implementing the method-prototype (EN 2135076 C1 IPC And 61 In 5/024, 1998) is also the prototype of the claimed invention. The device prototype contains opto-electronic Converter, including light-emitting and light-receiving sensors operating with multiple light flux, and the shaper of the pulse wave signal, whose input is connected to the output of the light-receiving sensor. The driver of the electric signal of the pulse wave is made in the form of a set of blocks analog-to-digital conversion, RAM and CPU agreed with the optoelectronic Converter.

The disadvantage of this method and device, it implements, is that the coincidence of the spectra of the signals of the pulse wave and interference from motion artifacts, it is not able to generate an electrical signal of the pulse wave, free of the interference, associated with modulation of the light flux from involuntary displacement sensors optoelectronic Converter controlled stretch of cruisesusa tissue.

The problem to which this invention is directed is to provide a method and device for registration of the pulse wave signal free from interference associated with modulation of the light flux from involuntary displacement sensors optoelectronic Converter controlled stretch of cruisesusa tissue.

Technical result achieved in the implementation of the present invention is to improve the noise immunity of registration of the pulse wave through the processing stations of the pulse wave signal that does not contain interference from motion artifacts.

Tasked with achieving the above-mentioned technical result is solved in that in the method of registering the pulse wave, which consists in the fact that the irradiated area cruisesusa tissue luminous flux, taking the scattered light flux modulated by the change of the blood in the vessels and capillaries in cruisesusa tissue, and form an electrical signal of the pulse wave, optionally form a signal offset light-emitting and light-receiving sensors optoelectronic transducer relative to the controlled area shelter is essay fabric, control the signal level of the bias and signal offset exclude parts of an electrical signal of pulse wave interference from motion artifacts from further processing.

The problem is solved also by the fact that the signal of the offset light-emitting and light-receiving sensors optoelectronic transducer relative to the controlled area cruisesusa tissue formed by the difference of the current and the previous measurement value of the impedance plot cruisesusa tissue under the sensor.

These additional procedures are the distinguishing features of the proposed method relative to the prototype method.

Technical implementation task of the device is that in the device for recording the pulse wave containing the optoelectronic Converter, including light-emitting and light-receiving sensors operating with multiple light flux, and the shaper of the pulse wave signal, whose input is connected to the output of the light-receiving sensor, put the block signal offset and the key, and the output of the signal shaper pulse wave is connected with the information input key, the control input of which is connected to the output of the processing unit offset.

The processing unit offset contains two MEAs the measuring electrode, connected to separate inputs of the meter impedance, the output of which is directly and through the delay unit, respectively connected to separate inputs of a comparator whose output is the output of the processing unit offset.

Structurally, the light-emitting and light-receiving sensors optoelectronic transducer and the measuring electrodes are rigidly connected with each other and are located on the surface of the phone earpiece in contact with a controlled stretch of cruisesusa tissue.

These additional blocks and communication are hallmarks of the claimed device relative to the device prototype.

The novelty of the present invention is to supply for further processing stations of an electrical signal of the pulse wave that does not contain interference from motion artifacts.

These symptoms distinguish the claimed method for detecting pulse waves and a device for its implementation the prototype and determine compliance with this decision, the criterion of "novelty". The invention is illustrated in the drawings, which depict:

figure 1 presents the structural electrical diagram of the device for reception of the pulse wave;

figure 2 presents a structural circuit diagram of the block signal offset;

figure 3 shows a diagram changed the value of the input parts of the device for reception of the pulse wave on the inner surface of the earpiece.

To register a pulse wave using diffused luminous flux. You can use indirect or direct the luminous flux modulated by the change of the blood in the vessels and capillaries in cruisesusa tissue. Live stream is used when the signal of the pulse wave from the ear lobe, ear, finger, nose. The reflected flux can be used to check the pulse wave when the signal pickup pulse wave with different areas of the body and the head, which because of their organoleptic properties cannot be obtained direct luminous flux.

The method is as follows.

Using the light-emitting sensor is irradiated area cruisesusa tissue luminous flux. With the help of the light-receiving sensor to receive reflected or direct light flux modulated by the change of the blood in the vessels and capillaries in cruisesusa tissue. Then form an electrical signal of the pulse wave in analog or digital forms. Simultaneously with the above-described processes form the signal offset light-emitting and light-receiving sensors relative to the controlled area of the blood tissue. Control the signal level of the offset and, if it cease the issuance of an electrical signal of the pulse wave.

The signal offset of the optoelectronic Converter is El relative to the controlled area cruisesusa fabric formed according to the difference of the current and previous with a constant time-shift, measurements of impedance values of the monitored stretch of cruisesusa tissue under the sensor optoelectronic Converter.

Any displacement of the sensor relative to the location of the signal pickup pulse wave causes the signal at the output of the comparator, prohibiting the passage of the pulse wave signal through the key. In the output electrical signal of the pulse wave is completely missing parts of the signal interference caused by modulation of the light flux from involuntary displacement sensors optoelectronic Converter controlled stretch of cruisesusa tissue.

Further description of the method is compatible with the description of the operation of the claimed device for implementing the method.

The device for recording the pulse wave (see figure 1) contains optoelectronic Converter 1, which includes a light-emitting 1.1 and the light-receiving 1.2 sensors, the output of which through the imaging unit 2 electric signal of the pulse wave is connected with the information input key 3, the control input of which is connected to the output unit 4 signal offset. The output of the key 4 is an output device.

Unit 4 signal offset contains (see figure 2) two measuring electrodes 4.1 and 4.2, which are respectively connected to separate inputs and the measurer of 4.3 impedance, the output of which is directly and through the block 4.4 delay respectively connected to separate inputs of a comparator 4.5, the output of which is the output of block 4 signal offset.

In this device, light-emitting 1.1 and the light-receiving 1.2 sensors optoelectronic transducer and the measuring electrodes 4.1 and 4.2 are located on the surface of the phone earpiece in contact with a plot of cruisesusa tissue.

The light emitting sensor 1.1 irradiates light (infrared) flow-place removal of the pulse wave. The use of the light-receiving sensor 1.2 reflected or direct signal depends on the specific designated pickup person signal of the pulse wave. At the location of the sensors 1.1 and 1.2 on the inner surface of the earphone is used, the reflected signal light flux from blood tissue for registration of the pulse wave. Sensors 1.1 and 1.2 in direct contact with the blood tissue of the head. There are two options for irradiation of blood tissue: continuous and discrete. In the first case, the luminous flux continuously irradiates the blood tissue and is characterized by large energy costs, which can lead to the heating of the irradiated tissues and a large consumption of electric power from the power source. The use of discrete variant of the light-emitting sensor is ka 1.1 implies the exposure of the blood tissue luminous flux, brightness is set to the oscillation frequency and duty ratio (for example, the frequency of exposure to 100 Hz, duty factor 10). The last variant is characterized by high energy efficiency, ability to use large values of brightness radiating flow and reduce the influence of illumination.

The radiation of the light flux in the light-emitting sensor 1.1, and the conversion of the light flux in the light-receiving sensor 1.2 can be carried out by traditional methods using commercially available LEDs and opto-pairs types AL, AL, AD, PD or photosensitive matrix (RU 2199943 C2, IPC And 61 In 5/02, 2001). The Builder 2 pulse wave signal is increased, filtering (for noise below or above the spectrum of the pulse wave signal) and further processed.

The operation key 3 is the permission/prohibition signal of the pulse wave at the output of the claimed device.

The basis of the processing unit displacement is the meter 4.3 impedance electrodes 4.1 and 4.2. Measuring 4.3 impedance measurement the impedance cruisesusa tissue under the light-emitting and light-receiving sensors. This measurement is carried out by traditional methods used in rheography. In rheography there are two schemes of dimension d is jelektrodnaja (bipolar) electrode and (tetrapolar). As an example of implementation in the inventive device uses a two-electrode scheme.

1. The generation of the pulse wave signal, consisting in the radiation controlled area cruisesusa tissue luminous flux, the reception of the scattered light flux modulated by the change of the blood in the vessels and capillaries in cruisesusa tissue, and the formation of an electrical signal of the pulse wave, wherein forming the signal offset light-emitting and light-receiving sensors optoelectronic transducer relative to the controlled area cruisesusa fabric according to the difference of the current and previous values of the signals of the impedance of the controlled area and in the presence of his form signal of the ban on the passage of an electrical signal of the pulse wave to exclude interference from motion artifacts from further processing.

2. Apparatus for forming a signal of pulse wave containing the optoelectronic Converter, including light-emitting and light-receiving sensors and the imaging unit of the pulse wave signal, whose input is connected to the output of the light-receiving sensor, wherein the processing unit offset contains two measuring electrodes connected to separate inputs of the meter impedance, the output of which is directly and through b is OK delay respectively connected to separate inputs of the comparator, the output of which being the output of the processing unit displacement, connected to the control input of the key, and the information input key is connected to the output of the shaper pulse wave.

3. The device according to claim 2, characterized in that the light-emitting and light-receiving sensors optoelectronic transducer and the measuring electrodes are rigidly connected with each other and are located on the surface of the telephone earpiece.



 

Same patents:

FIELD: medicine; medical engineering.

SUBSTANCE: method involves doing multi-channel recording of electroencephalogram and carrying out functional tests. Recording and storing rheoencephalograms is carried out additionally with multi-channel recording of electroencephalogram synchronously and in real time mode in carotid and vertebral arteries. Electroencephalograms and rheoencephalograms are visualized in single window with single time axis. Functional brain state is evaluated from synchronous changes of electroencephalograms, rheoencephalograms and electrocardiograms in response to functional test. The device has electrode unit 1 for recording bioelectric brain activity signals, electrode unit 2 for recording electric cardiac activity signals, current and potential electrode unit 3 for recording rheosignals, leads commutator 4, current rheosignal oscillator 5, synchronous rheosignal detector 6, multi-channel bioelectric brain activity signals amplifier 7, electrophysiological signal amplifier 8, demultiplexer 9, multi-channel rheosignal amplifier 10, multi-channel analog-to-digital converter 11, micro-computer 12 having galvanically isolated input/output port and personal computer 13 of standard configuration.

EFFECT: enhanced effectiveness of differential diagnosis-making.

11 cl, 6 dwg

FIELD: medicine.

SUBSTANCE: method involves recording rheogram from feet and legs lifted and fixed at an angle of 45є. Then, rheogram is recorded on inhaling from legs directed vertically downward. Functional blood circulation reserve index is calculated as product of results of dividing and subtracting rheographic indices recorded under conditions of lifted and lowered extremities that means under conditions of functional venous system relief and venous hypertension, respectively.

EFFECT: enhanced effectiveness in recognizing patient group suffering from severe lower extremities ischemia.

6 dwg

The invention relates to medicine, particularly cardiology and functional diagnostics

The invention relates to medicine, namely to measure parameters of cardiovascular system
The invention relates to medicine and can find application in neuro-ophthalmology

Plethysmograph // 2207804
The invention relates to medical equipment, namely, devices for studies of peripheral blood flow
The invention relates to medicine, sexologist, functional diagnostics
The invention relates to medicine, urology, functional diagnostics

FIELD: medicine.

SUBSTANCE: method involves recording rheogram from feet and legs lifted and fixed at an angle of 45є. Then, rheogram is recorded on inhaling from legs directed vertically downward. Functional blood circulation reserve index is calculated as product of results of dividing and subtracting rheographic indices recorded under conditions of lifted and lowered extremities that means under conditions of functional venous system relief and venous hypertension, respectively.

EFFECT: enhanced effectiveness in recognizing patient group suffering from severe lower extremities ischemia.

6 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves doing multi-channel recording of electroencephalogram and carrying out functional tests. Recording and storing rheoencephalograms is carried out additionally with multi-channel recording of electroencephalogram synchronously and in real time mode in carotid and vertebral arteries. Electroencephalograms and rheoencephalograms are visualized in single window with single time axis. Functional brain state is evaluated from synchronous changes of electroencephalograms, rheoencephalograms and electrocardiograms in response to functional test. The device has electrode unit 1 for recording bioelectric brain activity signals, electrode unit 2 for recording electric cardiac activity signals, current and potential electrode unit 3 for recording rheosignals, leads commutator 4, current rheosignal oscillator 5, synchronous rheosignal detector 6, multi-channel bioelectric brain activity signals amplifier 7, electrophysiological signal amplifier 8, demultiplexer 9, multi-channel rheosignal amplifier 10, multi-channel analog-to-digital converter 11, micro-computer 12 having galvanically isolated input/output port and personal computer 13 of standard configuration.

EFFECT: enhanced effectiveness of differential diagnosis-making.

11 cl, 6 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves irradiating blood-carrying tissue area under control with luminous flow, receiving scattered luminous flow modulated with blood filling changes in blood vessels and capillaries of blood-carrying tissue and forming electric signal of pulse wave. Deviation signal of light-emitting and light-receiving transducers of optoelectronic converter relative to blood-carrying tissue area under control based on difference between the current and preceding values of impedance signal on the area under control. The signal being observed, prohibition signal is produced on pulse wave electric signal passage for excluding errors caused by motion artifacts from its following processing. The device has optoelectronic converter having light-emitting and light-receiving transducers and unit for producing pulse wave signal, which input is connected to light-receiving transducer output. Unit for forming deviation signal has two measuring electrodes connected to separate comparator inputs which output being deviation signal former output, is connected to control input of key. Information input of the key is connected to pulse wave signal former output.

EFFECT: improved noise immunity.

3 cl, 3 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves recording multichannel electroencephalogram, electrocardiogram record and carrying out functional test and computer analysis of electrophysiological signals synchronously with multichannel record of electroencephalogram and electrocardiogram in real time mode. Superslow brain activity is recorded, carotid and spinal artery pools rheoelectroencephalogram is recorded and photopletysmogram of fingers and/or toes is built and subelectrode resistance of electrodes for recording bioelectrical cerebral activity is measured. Physiological values of bioelectrical cerebral activity are calculated and visualized in integrated cardiac cycle time scale as absolute and relative values of alpha-activity, pathological slow wave activity in delta and theta wave bandwidth. Cerebral metabolism activity dynamics level values are calculated and visualized at constant potential level. Heart beat rate is determined from electrocardiogram, pulsating blood-filling of cerebral blood vessels are determined from rheological indices data. Peripheral blood vessel resistance level, peripheral blood vessel tonus are determined as peripheral photoplethysmogram pulsation amplitude, large blood vessel tonus is determined from pulse wave propagation time data beginning from Q-tooth signal of electrocardiogram to the beginning of systolic wave of peripheral photoplethysmogram. Postcapillary venular blood vessels tonus is determined from constant photoplethysmogram component. Functional brain state is determined from dynamic changes of physiological values before during and after the functional test. Device for evaluating functional brain state has in series connected multichannel analog-to-digital converter, microcomputer having galvanically isolated input/output ports and PC of standard configuration and electrode unit for reading bioelectric cerebral activity signals connected to multichannel bioelectric cerebral activity signals amplifier. Current and potential electrode unit for recording rheosignals, multichannel rheosignals amplifier, current rheosignals generator and synchronous rheosignals detector are available. The device additionally has two-frequency high precision current generator, master input of which is connected to microcomputer. The first output group is connected to working electrodes and the second one is connected to reference electrodes of electrode unit for reading bioelectrical cerebral activity signals. Lead switch is available with its first input group being connected to potential electrodes of current and potential electrodes unit for recording rheosignals. The second group of inputs is connected to outputs of current rheosignals oscillator. The first group of outputs is connected to current electrodes of current and potential electrodes unit for recording rheosignals. The second group of outputs is connected to inputs of synchronous detector of rheosignals. Demultiplexer input is connected to output of synchronous detector of rheosignals and its outputs are connected to multichannel rheosignals amplifier inputs. Outputs of multichannel bioelectrical cerebral activity signals amplifier, multichannel rheosignals amplifier and electrophysiological signal amplifier are connected to corresponding inputs of multichannel analog-to-digital converter. Microcomputer outputs are connected to control input of lead switch, control input of multichannel demultiplexer, control input of multichannel analog-to-digital converter and synchronization inputs of current rheosignals oscillator and synchronous detector of rheosignals. To measure subelectrode resistance, a signal from narrow bandwidth current generator of frequency f1 exceeding the upper frequency fup of signals under recording is supplied. A signal from narrow bandwidth current generator of frequency f2≠ f1>fup is supplied to reference electrode. Voltages are selected and measured at output of each amplifier with frequencies of f1, f2 - Uf1 and Uf2 using narrow bandwidth filtering. Subelectrode resistance of each working electrode is determined from formula Zj=Ujf1 :(Jf1xKj), where Zj is the subelectrode resistance of j-th electrode, Ujf1 is the voltage at output from j-th amplifier with frequency of f1, Kj is the amplification coefficient of the j-th amplifier. Subelectrode resistance of reference electrode is determined from formula ZA=Ujf2 :(Jf2xKj), where ZA is the subelectrode resistance of reference electrode, Ujf2 is the voltage at output from j-th amplifier with frequency of f2, Jf2 is the voltage of narrow bandwidth current oscillator with frequency of f2.

EFFECT: wide range of functional applications.

15 cl, 10 dwg

FIELD: medicine, surgery.

SUBSTANCE: one should evaluate clinical state of a patient and as objective parameters one should calculate rheological and brachio-malleolar indices, detect fractional tension of oxygen in capillary blood. At observing clinical improvement accompanied by increased rheological and brachio-malleolar indices by more than 0.1, increased blood saturation with oxygen by more than 10 mm mercury column one should state upon a "good" therapeutic effect. At detecting clinical improvement accompanied by the increase of either one or several objective parameters, or if dynamics of these values is not available - effect should be considered as a "satisfactory" one. At kept ischemic pain at rest without decrease of its intensity, impossibility to keep a limb in horizontal position for a long period of time, the absence of positive dynamics of trophic disorders, at kept ischemic edema and at no alterations in objective parameters - should be determined as "no dynamics". In case of enhanced ischemic pain and edema of foot, at progressing necrotic alterations in foot - one should detect "deterioration" of patient's state. The method increases the number of diagnostic means.

EFFECT: higher accuracy of evaluation.

1 ex, 1 tbl

FIELD: medicine.

SUBSTANCE: method involves recording peripheral differential upper extremity blood vessel rheogram and phonocardiogram in synchronous way. The second phonocardiogram beginning and the deepest rheogram points are detected. Pulse way propagation time reduction being found, arterial bloodstream tone growth conclusions are drawn.

EFFECT: high reliability of the results.

18 dwg, 3 tbl

FIELD: medicine, neurology.

SUBSTANCE: a patient should be in initial position when his/her sight is directed towards the ceiling and in 3-5 min it is necessary to register a background rheoencephalogram, then a patient should fix the sight at a pointer's tip being at the distance of about 30 cm against the bridge of nose along the middle line, then the sight should be directed into marginal position due to shifting pointer to the left. Then the sight should be returned into initial position and 3 min later it is necessary to register rheoencephalogram of vertebro-basilar circulation, calculate rheographic index (RI), coefficient for RI ratio on returning the sight from left-hand marginal position into initial one (k2) and at k2>1.098 from the left and (or) k2>1.085 from the right one should detect alteration in vertebro-basilar circulation by reflector mechanism. The method excludes biomechanical impact in stimulating proprioceptive receptors of muscular-ligamentous system under stretching.

EFFECT: higher accuracy and reliability of detection.

2 ex, 2 tbl

FIELD: medicine, resuscitation.

SUBSTANCE: one should detect cerebral perfusion pressure (CPP), intracranial pressure (ICP), values for blood saturation with oxygen in radial artery and jugular vein bulb (SaO2, SjO2), additionally one should study lactate level in jugular vein bulb and radial artery, calculate venous-arterial difference according to lactate (▵lactate), cardiac ejection (CE) due to thermodilution and hemoglobin level. Values for cerebral oxygen transport function should be calculated by the following formulas: mĎO2 = 0.15 x CE x CaO2 x 10; mVO2 = 015 x CE x (CaO2 - CjO2) x 10; CaO2 = 1.3 x Hb x SaO2; CjO2 = 1.3 x Hb x SjO2. In case of noninvasive detection - due to pulsoxymetry one should measure peripheral saturation (SpO2), due to parainfrared spectroscopy - cerebral oxygenation (rSO2) and cardiac ejection due to tetrapolar rheovasography (CEr), detect and calculate the values of cerebral oxygen transport system according to the following formulas: mĎO2 = 0.15 x CEr x CaO2 x 10; mVO2 = 0.15 x CEr x (CaO2 - CjO2) x 10; CaO2 = 1.3 x Hb x SpO2; CjO2 = 1.3 x Hb x rSO2. At the value of mĎO2 86-186 ml/min and more, MVO2 33 - 73 ml/min, ▵lactate below 0.4 mM/l one should evaluate cerebral oxygen transport system to be normal and the absence of cerebral metabolic disorders. At mĎO2 values below 86 ml/min, mVO2 being 33-73 ml/minO2, ▵lactate below 0.4 mM/l one should state upon compensated cerebral oxygen transport system and the absence of metabolic disorders. At mĎO2 being below 86 ml/min, mVO2 below 33 mM/l, ▵lactate below 0.4 mM/l one should conclude upon cerebral oxygen transport system to be subcompensated at decreased metabolism. At the values of mĎO2 being 86-186 ml/min and more, MVO2 below 33 ml/min, ▵lactate below 0.4 mM/l one should establish subcompensated cerebral oxygen transport system at decreased metabolism. At values of lactate being above 0.4 mM/l and any values of mĎO2 and mVO2 one should point out the state of decompensation in cerebral oxygen transport system and its metabolism. The innovation enables to diagnose disorders and decrease the risk for the development of secondary complications.

EFFECT: higher efficiency and accuracy of evaluation.

1 cl, 3 ex, 1 tbl

FIELD: medicine.

SUBSTANCE: method involves setting a patient in vertical posture with stabilogram and rheoencephalogram being concurrently recorded with frontomastoid and accipitomastoid leads being used retaining head position with stressed neck extensor muscles state and head position with relaxed neck extensor muscles state. Stabilogram parameters characterizing vertical posture stability and rheographic index of each of four brain basins. When combining better filling of cerebral basins with blood and higher standing stability, training is carried out in keeping head positions allowing better filling of cerebral basins. If better filling of cerebral basins with blood follows with no increased standing stability, the trainings are carried out in keeping head position with stressed neck extensor muscles state. The training sessions are given twice a day for 15 min during two weeks.

EFFECT: enhanced effectiveness of treatment.

2 cl, 3 tbl

FIELD: medicine.

SUBSTANCE: method involves determining pulsating arterial blood flow parameters. To do it, measuring electrodes are applied in main liver body mass location zone. Electrode-to-electrode distance is additionally measured and hepatic index is calculated from formula HI=ρ*L2*Ad*ET*HBR/Z2*1000*S, where HI is the hepatic index (l/min/m2), ρ is the constant reflecting volume blood resistance (150 Ohm cm), L is electrode-to-electrode distance (cm), Z is the base impedance (Ohm), Ad is the differential rheogram amplitude (Ohm/s), ET is blood expulsion time (s), HBR is heart beat rate per 1 min, S is the body surface (m2), 1000 is the coefficient for converting to liters. HI value being greater than 0.225 l/min/m2, porto-portal and/or porto-central hepatic fibrosis is diagnosed.

EFFECT: wide range of functional applications.

2 tbl

Up!