Antiinflammatory and wound-healing ointment

FIELD: pharmaceutical industry.

SUBSTANCE: invention provides antiinflammatory and wound-healing ointment based on natural components, which invention, along with vegetable oils, may further contain ursine fat, ursine bile, propolis, lanoline, honey, and mummified guano. Variously formulated ointments can be used for treating hemorrhoids, burns, antritis, post-stroke condition, gunshot and stab-punctured wounds, trophic ulcer, postoperative fistula, oophoritis, diabetic microangiopathy of lower extremities, as well as papillomas, birthmarks, seborrhea, and psoriasis.

EFFECT: expanded therapeutical possibilities.

6 cl, 17 ex

 

The invention relates to medicine, namely to treatment ointments that have anti-inflammatory and wound healing properties.

Known ointment with protivogemorroidal effect, containing vegetable ingredients of the following composition, parts by weight: oak bark 2-3, agrimonia ordinary 2-4, the flowers of red clover 2-4, chamomile flowers 3-5, grass budry plyuschevidnaya 4-6, grass clover 4-6, herb Hypericum perforatum 3-5, marigold flowers 2-4, leaf plantain 2-4, sheet sage 1-3, herb yarrow 2-4, grass cudweed herb swamp 5-7, flowers of tansy 4-6, grass cinquefoil goose 4-6, as well as the internal fat pork 160 (RF Patent N 2008012, MKI a 61 K 35/78, 1994 g).

For the prototype was chosen ointment, including botanicals in the form of a 40%alcohol tincture herbs Campion Tatar or drooping 3 wt. 'clock, calendula flowers 1 wt. hours, leaves of fireweed herb to 1 wt. o'clock, as well as petrolatum and lanolin, taken in the ratio of 7:2 (RF Patent N 2135277, a 61 K 35/78, 9/06, 1999). The ointment is intended for the integrated treatment of burn and posttraumatic wounds.

The disadvantage of ointments is a narrow range of therapeutic effects on the body.

The aim of the present invention is to expand the range of therapeutic effects on the body and expanding the range of anti-inflammatory ointments and ranos gillaume actions.

This objective is achieved in that ointment N 1 anti-inflammatory and wound-healing actions, including botanicals and lanolin contains as plant components oil, aloe oil, Mandrake root, and optionally contains honey, mummy, bear fat at the following mass ratio of components: 1:1:1:1:1:1.

Ointment N 2, including botanicals and lanolin contains as plant components oil, aloe Vera, oil, plantain, oil of sea-buckthorn berries and additionally contains honey, mummy, bear fat at the following mass ratio of components: 1:1:1:1:1:1:1.

Ointment N 3, including botanicals and lanolin contains as plant components oil, aloe Vera, oil, plantain, oil sazegara intoxicating and additionally contains honey, mummy, bear bile, bear fat at the following mass ratio of components 1:1:1:1:1:1:1:1.

Ointment N 4, including botanicals and lanolin contains as plant components oil, aloe Vera, oil, plantain oil, Mandrake root, oil Kalanchoe, oil korostenka, garlic oil and additionally contains honey, mummy, birch tar at the following mass ratio of components: 1:1:1:1:1:1:1:1:1:1.

Ointment N 5, including botanicals and lanolin contains as rastiteljnostj oil aloe oil, plantain oil, Mandrake root, oil of sweet clover, oil Kalanchoe, oil korostenka, oil Cassandra, oil cleaning large oil Andromeda, Ledum oil and optionally contains honey, mummy, bear bile at the following mass ratio of components: 1:1:1:1:1:1:1:1:1:1:1:1:1:1.

Ointment N 6, including botanicals and lanolin contains as plant components oil, plantain oil, clover oil of sea-buckthorn berries oil, herb, calendula oil, oil ephedra Equisetum, St. John's wort oil, oil of fireweed herb, butter buds, butter buds of birch, fir oil, and optionally contains honey, mummy, bear bile, propolis at the following mass ratio of components: 1:1:2:1:1:1:2:1:2:1:1:1:2:2:2:2.

The ointment is prepared as follows. Oils of medicinal plants are prepared in a known manner. In dosed mixture of the fatty components (lanolin, bear fat) is injected alternately oils of medicinal plants and other above-mentioned components. Stirring is carried out until a homogeneous mass.

Examples of clinical application of ointments.

Example 1.

Use the ointment N 1 for the treatment of hemorrhoids.

Patient O. 52. Complaints of sharp pain and itching in the anus, prolapse hemorrhoids, bleeding and difficulty in defecation. For the treatment of destinations is on the ointment N 1, which was introduced into the rectum by using tampons and smeared the external opening of the rectum. A week later, the patient had no pain and itching in the anus, defecation was free, stopped the bleeding. The treatment lasted for months. After treatment seals hemorrhoids has disappeared, vanished all the symptoms of the disease. The patient is recommended to periodically apply the ointment N 1 for the prevention of hemorrhoids.

Example 2.

Use the ointment N 1 for the treatment of burns.

Patient M is 4 years. The child burn 2nd degree of buttock, complicated infected. The treatment was performed ointment N 1 by overlaying it on the burn with subsequent fixation. Change dressings were carried out daily. 10 days later the lesion was not painful, the contents of the bubbles partially resorbed, redness around the burn was reduced. The treatment lasted 38 days. On the layout of the burn remained pigmented. Ointment N 1 prevented the formation of scars.

Example 3.

Use the ointment N 1 for the treatment of sinusitis.

The patient, 31 years. Complaints about stress in the area of the sinuses, impaired nasal breathing, headache, weakness. The body temperature of 37.6°C. the Patient noted that in the last 3 years did punctures. For the treatment applied ointment N 1. A small amount of ointment was smeared slid the net membrane of the nose and rubbed it in the maxillary region, frontal sinus and the superciliary arches 3 times a day. After 4 days the body temperature returned to normal, headache. From the nose periodically retreated purulent discharge, breathing became free. Three-week course of treatment took all the symptoms of the disease. The patient felt well.

Example 4.

Use the ointment N 1 for the treatment of post-stroke state.

Sick So - 67. After stroke complaints about reduced sensitivity and mobility of the right leg and right arm, and numbness of the fingers and toes. Recommended daily rubbing ointment N 1 both limbs, especially of the joints and spine from the sacrum to occiput. Rehabilitation treatment after stroke was carried out within 3 months. After treatment increased the sensitivity and mobility of the right arm and leg. Numbness and stiffness of the fingers and toes of the patient did not feel and could take care for himself. Improved psycho-emotional state of the patient.

Example 5.

Use the ointment N 2 for treatment of a gunshot wound.

Patient K. - 24 years. He received a gunshot wound in the region of the forearm. The wound is deep and infected. The fraction held in the tissue of the forearm. Shoulder joint and bones are not affected. Pain from wandering fractions and shivering. The body temperature of 37.8°C. To ensure used the ointment N 2, which is daily for 3 months rubbed in the field penetrating wounds and distribution of the fraction. On the third day returned to normal body temperature and chills disappeared. As rubbing ointment fraction gradually appeared on the surface. 3 months went 7 fragments fraction. Wound healing was carried out without scarring.

Example 6.

Use the ointment N 2 for the treatment of varicose veins and ulcers.

Patient Z. - 39 years. Complaints about varicose veins on both legs and on the formation of ulcers on the right foot. Recommended patient daily for 45 days RUB ointment easy no pressure pumping movements in both legs, especially in areas affected veins. The ulcer was bandaging with ointment. The healing of ulcers occurred in 18 days and only pink skin tone betrayed her location. Nodules veins become softer some of them (at the bend in the leg, below the knee) disappeared. The skin of the feet has become healthy. The patient was recommended to continue rubbing the ointment within 15 days to consolidate therapeutic effect.

Example 7.

Use the ointment N 3 for the treatment of postoperative fistula.

Patient Century - 34 years. Complaints about non-healing seam, rough cut and sinus area caesarean section. 8 days after discharge the patient was found that oozes out of the joint fluid. Treatment ointment N 3 that was done on the scar and fistula, and put the wads with ointment into the vagina. Che the ez will give the fistula completely disappeared and the pain stopped. After conducting a 30-day course of treatment scar resorbed, the seam has become lighter and thinner.

Example 8.

Use the ointment N 3 for treatment of an inflammation of appendages.

Patient S., 23 years. Complaints about pain in the region of the uterus and sacral spine, the menstrual cycle and the selection whiter. The patient had previously received antibiotics, which temporarily removed the symptoms. Recommended rubbing ointment N 3 in the pubic and inguinal region, as well as in the area of the appendages and sacral spine. In addition, it is proposed to put the wads with ointment into the vagina in the intermenstrual period every night. After 10 days of treatment was resumed menstrual cycle a little earlier than expected. Menstrual flow was accompanied by pain, were more abundant, but short. After 3 days the patient continued treatment. The course of treatment was 30 days. The subsequent menstrual periods became more regular, without pain. Selection whiter was not observed. During the year recurrence of the disease was not.

Example 9.

Use the ointment N 4 for the treatment of venous ulcers.

Patient A. - 49 years. Filed a complaint on the trophic ulcer in the area of the right lower limb. Examination showed that his right leg had a dark brown color, ankle swollen, red, inflamed color. Weeping ulcer is located on the lane the day side of the leg. To ensure assigned ointment N 4, which is applied once daily on the plague, and easily rubbed into the area of redness and inflammation. From ulcers for some time was allocated ichor, but on the 6th tribute to treat the wounds started healing, half asleep swelling of the legs. 2 weeks later the swelling had completely gone and ulcer dragged new thin skin. The patient exercised daily rubbing ointment without interruption within 3.5 months. The circulation in the leg is normalized. Recurrence was not observed.

Example 10.

Use the ointment N 4 for the treatment of diabetic microangiopathy of the lower extremities.

Patient C. - 53 years. Observed at the endocrinologist in occasion of diabetes. Filed a complaint at the sharp pain in the big toe of the right leg, the blackening of the nail. The gangrenous leg, swollen, inflamed tissue from the toe to the ankle. The patient is recommended strict adherence to the diabetic diet. Assigned treatment ointment # 4. Ointment daily applied on the affected leg. Three days later the swelling of the legs, pain in the thumb decreased. A month later, with the patient's finger came down the nail. The treatment lasted for three months. Normalized circulation in the leg. The patient has no symptoms.

Example 11.

Use the ointment N 4 for the treatment of burns.

Patient I. - 34 years. Appealed to burn 3-the extent received from exposure to electric current. Affected both the brush and the phalanges of the hands. Wounds are not infected. After processing the burn with a weak solution of potassium permanganate, the wound was imposed ointment N 4 with subsequent fixation. The treatment lasted for 45 days without a break. Wound healing occurred quickly, without scarring. The patient was also recommended exercises to restore hand. At the end of the treatment course the patient has fully recovered the operability of the hand.

Example 12.

Use the ointment N 5 for the treatment of papillomas.

Patient W. - 49 years. Complaints of papilloma in the neck, chest. Assigned ointment N 5, which the patient daily and rubbed in the layout area of papillomas. In parallel recommended to undergo a course of cleansing enemas scheme: 4 days per month, entering with mugs esmarkha respectively of 0.5, 1.0, 1.5 and 2.0 liters of water. The course of treatment was 2.5 months. In the treatment of papilloma began to dry up, to darken, and then became hard and fall off. By the end of treatment number of papillomas was reduced 3 times. After 3 months, the patient repeated the treatment, which was achieved complete clearance of the skin papillomas.

Example 13.

Use the ointment N 5 for the treatment of birthmarks.

Patient F. - 7 years. On the forearm were hard, rough, dark bug is anoe birthmark with blood points. Birthmark was ochotorena fair skin. Recommended treatment ointment N 5. Ointment rubbed in over 8 months, and each month take a break for 10 days. By the end of the first month birthmark became softer, softer to the touch. As continuation blood point was pale and was resolved. After treatment birthmark disappeared completely.

Example 14.

Use the ointment N 5 for the treatment of psoriasis.

Patient L. - 19 years. Diagnosis: psoriasis, often growing in the cold season. Struck the face and scalp all year round, and the hands, forearm and chest periodically. On the scalp rashes were weeping, extensive, painful, face red rough spots. The patient was in a state of depression. Treatment ointment N 5. After 5 days of treatment plaque was softened, rarely reduced redness, decreased itching. Two weeks later the scalp completely cleared from psoriatic plaques. The skin on the body after 2.5 months was healthy. Improved psycho-emotional condition of the patient.

Example 15.

Use the ointment N 6 for the treatment of wounds.

Patient C. - 29 years. Received on the production of stabbing wounds of the wrist, affected bone. The wound is infected. Hand turned red and swollen. Treatment ointment N 6. The wound disinfectant on the wound with the Ali daily to apply the ointment. Swelling and redness of the wound disappeared on the second day of the application of the ointment. Wound healing occurred in 9 days. The wound healed without complications. After 20 days of treatment left a small mark on the place penetrating wounds.

Example 16.

Use the ointment N 6 for the treatment of seborrhea.

Patient R. 32 years. Turned diagnosed with seborrhea of the scalp. Hair greasy, the skin has a greasy luster. In some parts of the head is observed flaky skin (dandruff). For the treatment applied ointment N 6, which daily rubbed into the scalp. After 8 days of treatment the scalp cleansed from dandruff, oily skin luster disappeared. The patient was excluded shampoos, Soaps head with baby soap and continued rubbing ointment for 3 weeks. Upon completion of treatment the patient visited a skin doctor who took previously diagnosed.

Example 17.

Use the ointment N 6 for the treatment of gangrene.

Patient U. 58. Addressed with gangrene of the left leg. After treatment in the clinic doctors suggested amputation. The patient complained of severe pain in her leg, and walked with crutches. The patient's condition is complicated by hypertension and unstable glucose levels and blood. Treatment ointment N 6. After applying the ointment patient on the 7th day felt the pain. The redness began to subside and 17-s the day did not rise above the ankle. The foot remained swollen. The toe was black and dry. A month later, the question arose about the amputation 1 phalanx of the thumb, as dead dry tissue was not allowed to complete the recovery. Was eventually removed one phalanx of the great toe. To heal wounds again applied the ointment N 6, which is rubbed into the skin to the knee, to improve circulation. Wound healing occurred on the 4th day. The skin of the legs had a natural healthy look. Swelling disappeared. The patient began to move without crutches. Stabilized level of blood sugar by observing the patient a strict diet.

Example 1-17 follows that the proposed ointment has anti-inflammatory, wound healing, analgesic, biodegradable, antibacterial, antiseptic, adavipolam, blood purifying action, restores regenerative tissue functions, regulates hormonal and metabolic processes in the body.

The ointment can be applied for the treatment of hemorrhoids, burns, sinusitis, post-stroke state, gunshot and stab wounds, trophic ulcers, postoperative fistula, inflammation of appendages, diabetic microangiopathy of the lower extremities, as well as papillomas, birthmarks, seborrhea and psoriasis, which allows to expand the range of therapeutic effects on the body and to expand the range of m is of sa anti-inflammatory and wound-healing action.

When using the ointment does not have any harmful side effects on the body and has no contraindications for use. The ointment can be used for the treatment of adult patients and children.

1. Ointment anti-inflammatory and wound-healing actions, including botanicals and lanolin, characterized in that the quality of herbal ingredients it contains oil, aloe oil, Mandrake root, and optionally contains honey, mummy, bear fat mass ratio of components 1:1:1:1:1:1.

2. Ointment anti-inflammatory and wound-healing actions, including botanicals and lanolin, characterized in that the quality of herbal ingredients it contains oil, aloe Vera, oil, plantain, oil of sea-buckthorn berries and additionally contains honey, mummy, bear fat mass ratio of components 1:1:1:1:1:1:1

3. Ointment anti-inflammatory and wound-healing actions, including botanicals and lanolin, characterized in that the quality of herbal ingredients it contains oil, aloe Vera, oil, plantain, oil sazegara openaudio and additionally contains honey, mummy, bear bile, bear fat mass ratio of components 1:1:1:1:1:1:1:1

4. Ointment anti-inflammatory and wound-healing actions, including botanicals and lanolin different is connected with the fact, as herbal ingredients it contains oil, aloe Vera, oil, plantain oil, Mandrake root, oil Kalanchoe, oil korostenka, garlic oil and additionally contains honey, mummy, birch tar when the mass ratio of the components 1:1:1:1:1:1:1:1:1:1

5. Ointment anti-inflammatory and wound-healing actions, including botanicals and lanolin, characterized in that the quality of herbal ingredients it contains oil, aloe Vera, oil, plantain oil, Mandrake root oil, clover oil, Kalanchoe, oil korostenka, oil Cassady, oil cleaning large oil Pamela, Ledum oil and optionally contains honey, mummy, bear bile when the mass ratio of the components 1:1:1:1:1:1:1:1:1:1:1:1:1:1.

6. Ointment anti-inflammatory and wound-healing actions, including botanicals and lanolin, characterized in that the quality of herbal ingredients it contains oil, plantain oil, clover oil of sea-buckthorn berries oil, herb, calendula oil, oil ephedra homeboy, St. John's wort oil, oil of fireweed herb, butter buds, butter buds of birch, fir oil, and optionally contains honey, mummy, bear bile, propolis when the mass ratio of the components 1:1:2:1:1:1:2:1:2:1:1:1:2:2:2:2.



 

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