"antipsoriaz" cream

FIELD: pharmaceutical industry.

SUBSTANCE: invention relates to developing medicaments in the form of ointment based on vegetable components and designed, in particular, to treat psoriasis as well as fungus diseases and can also be used in cosmetology. Psoriasis treatment cream includes water extracts of bur-marigold (Bidens tvipartita), white birch leaves (Betula alba L), greater celandine (Chelidonium majus), calendula (Calendula officanalis L), cudweed (Gnphalium uliginosum L), medical vaseline, lanolin, camphor, linseed oil, and medical solid oil at specified proportions of components.

EFFECT: increased treatment efficiency, avoided use of chemical additives, and prolonged shelf time.

 

The invention relates to the medical industry, namely the creation of medicines in the form of creams based on vegetable components, is intended, in particular, for the treatment of psoriasis, and fungal infections and can be used in cosmetology.

From prior art it is known the use of various medicinal ointments for the treatment of skin diseases, particularly psoriasis. So in ed. St. USSR N 198530, class a 61 K 9/06, 1965 described the ointment, which includes fine sulfur 5% emulsifier N 1 18% glycerol 2,8% citric acid 0,003% brown alcohol 0,15% and distilled water 74,047% Known also use "Emulsol" - a mixture of 90% emulsion of grease and 10% vaseline (ed. St. USSR N 351544, class a 61 K 9/06, 1970) and 10-percentage ointments or 2-percentage of oil solutions based on Chrysarobin" (ed. St. N 704619, CL a 61 K 35/78, 1968) for the treatment of skin diseases, including psoriasis.

These tools are not effective enough and require long-term use.

Known ointment for the treatment of various skin diseases, including psoriasis (RF patent N 1787033, class a 61 K 35/78, 1993)containing the powder of the seed of Psoralea kostandovo (Psoralea drupaceo Bye), penicillin and vaseline. The ratio of components, wt.%: the powder of the seed of Psoralea kostandovo - 2,0-2,5, penicillin - 4,5-5,5, petrolatum else. However, the presence of fines is Illina limits the possibility of its use due to possible allergic reactions.

Known ointment, which consists of adipose (fat bear, and/or mink, and/or badger, and/or pork and/or calendula oil, and/or St. John's wort oil and/or butter milk Thistle, and/or mint oil and/or safflower oil and/or olive oil) and the active component of plant origin (10% aqueous-alcoholic extracts of yarrow, and/or hops, and/or calamus, and/or thyme, and/or nettle, and/or calendula, and/or celandine, and/or cleaning and/or St. John's wort, and/or burdock, and/or gorse) in the following ratio, wt.%: 10%aqueous alcoholic extracts - 20-25, fat basis - the rest. For the treatment of psoriasis it contains mercury in a quantity of 0.001 wt.% (patent RF №2151594, a 61 K 9/06, a 61 K 35/78, 2000).

Known ointment for the treatment of psoriasis. In the ointment includes products of natural origin: a series of tripartite, greater celandine, birch tar, sorrel horse (RF patent No. 2171682, class a 61 K 9/06; a 61 K 35/78, 2001).

Most similar in content components and therapeutic purpose is the ointment for the treatment of psoriasis, comprising as active substances a large number of components of natural origin (RF patent N 2091065, class a 61 K 9/06; 35/78, 1997).

In the composition of ointments come in, wt.%: the Manchurian aralia - 0,9-1,0; burdock felt - 0,9-1,0; a series of tripartite - of 0.95-1.1 celandine - 0,9-1,15 flowers lnjanki - 0,4-0,6 ahnfeltia - 1,0-1,gumarabic - 0,4-0,6; glycobiologie mucus - 0,4-0,6; chitin of crab - 1,9-2,0; birch tar - 0,5-0,6; essential oil fir Belokolos - 0,4-0,5; wasgonna water fir Belokolos of 0.4 - 0.6; grease medical - rest. This ointment is versatile enough. However, preparation of starting materials is much more difficult and quite complex because of the large number of components are not readily available.

The claimed invention solves the problem of creating ointment with greater efficacy for the treatment of psoriasis and reduce the overall treatment time. In addition, simplification is achieved creating ointments, stable in composition from natural products without chemical additives with a long shelf life.

The problem is solved in that ointment for the treatment of psoriasis is characterized by the fact that it contains aqueous extracts of Bidens tripartite (Bidens tvipartita), leaves of white birch (Betula alba L.), celandine (Chelidonium majus), calendula (Calendula officinalis L), marsh cudweed herb (Gnaphalium uliginosum) and oil extracts of the same plants, as well as the fatty phase, including medical petroleum jelly, lanolin, camphor, linseed oil and grease medical, in the following ratio, wt.%:

aqueous extract of Bidens tripartite

(Bidens tvipartita) - 0,1-2,9;

an aqueous extract of the leaves of the white birch

(Betula alba L) - 0,1-3,5;

water ex is ract celandine

(Chelidonium majus) - 0,1-2,9;

aqueous extract of calendula

(Calendula officinalis L) - 0,1-2,9;

an aqueous extract of the marsh cudweed herb

(Gnaphalium uliginosum) - 0,1-2,0;

vaseline medical - 0,1-2,0

lanolin - 1,1-5,0

camphor - 0,1-0,5

linseed oil - 0,9-1,0

the grease medical - else

the ratio of water and oil extracts of plants is 5:1.

Ointment called “Antipsoriasis”.

In the phytocream “Antipsoriasis” used products “cold pressed”, i.e. water extracts juices of fresh plants, obtained immediately after collection. Products “cold pressed” is the number of critical components in the tissue, for the destruction that would require the effort of more than 2 tons KVM Possible pre-dissolving juices of fresh plants - product “cold pressed” in organic oils, such as linseed oil.

Part of the phytocream introduced camphor oil, which contributes to more complete penetration of botanicals in the lower layers of the skin due capillariasis and warming action.

The ointment is prepared as follows. Water extracts juices used plant - products “cold pressed” - receive immediately after collection. Next, a portion of the dried these plants in the shade at a temperature of 25-30°pulverized into powder by ultrafine grinding fractional composition particles to 0.01 mm. Ultrafine grinding not only creates the perfect skin comfort, but also allows you to extract much more number of healing components. The linear decrease of the particle size from 0.3 to 0.01, i.e. in 30 times, increases the reaction area of contact 900 times and gives the possibility of stepwise extraction of practically the entire spectrum of biologically active substances. The first stage translates into an aqueous solution of thermounstable substances. The active components of the plants transferred to the aqueous phase by infusion for 6-8 hours at a temperature of 70-75°in thermostatic vessel or by boiling in water bath for 30-40 minutes While die spores of microorganisms that may be present in the plant material. But most components, however, remains not recovered. The main part is extracted in the second stage at a temperature of not less than 100°With a new portion of herbs by passing steam through the mixture of plants or by heating in an autoclave for 10-20 min and or couple to obtain a solution. Combining water extracts and oil extracts of the same plants receive the mixture, which includes all biologically active substances from thermally unstable difficult to extract. Then the solutions are mixed with the fat phase at a temperature of 80-90°until complete homogenization at the next sod is the neigh ingredients wt %:

aqueous extract of Bidens tripartite

(Bidens tvipartita) - 0,1-2,9;

an aqueous extract of the leaves of the white birch

(Betula alba L) - 0,1-3,5

aqueous extract of celandine

(hlidnium majus) - 0,1-2,9

aqueous extract of calendula

(Calendula officinalis L) - 0,1-2,9

an aqueous extract of the marsh cudweed herb

(Gnaphalium uliginosum) - 0,1-2,0

vaseline medical - 0,1-2,0

lanolin - 1,1-5,0

camphor - 0,1-0,5

linseed oil - 0,9-1,0

the grease medical - rest.

the ratio of water and oil extracts of plants is 5:1.

The resulting mass was incubated for 1-2 months to move drugs into the fatty phase by spontaneous molecular diffusion. Manufactured ointment Packed in standard packaging with sealed lids.

Fitomazi “Antipsoriasis” rubbed into the affected skin until completely absorbed in the skin. Rubbing is performed in the evening hours twice with an interval of 2-3 hours. Qualitative rubbing ointment improves microcirculation in the skin and surrounding tissues, enhances the transport of nutrients to the affected areas. In the morning fitomazi can be washed off.

The second method of applying the phytocream 3 days in a row ointment scrub 1-2 times a day, and then make a break of one day.

Ointment “Antipsoriasis” includes components that allow p and proper rubbing of the affected area as if to create an analogue of a well-functioning, healthy skin. When this blocks unwanted access to patient skin of oxygen, is a barrier to the inflammatory process and the formation of new lesions. In the early days of applying the phytocream may be slight redness, itch, but these effects disappear within a few days. Real noticeable results appear in 25-35 days. Complete purification takes several months. “Antipsoriasis” additionally, you can RUB into zones of lymph nodes, axillary, submandibular or inguinal.

Example.

Sick Vermaelen VI ill psoriasis 15 years ago. Complaints of rash around the skin, periodic skin itch. First psoriatics rash appeared under the arms and hands in 1987, then red spots appeared all over the body and covered with plaques. Spots with plaques were 10 a penny coin, and by 1989 had reached a size of saucers. Notes exacerbation of dermatitis in the autumn-winter period. Since 1989, was seriously engaged in treatment. Went to various doctors, were treated with different drugs - hormonal and non-hormonal - for a long time. Were outpatients and inpatient with temporary improvement. Diagnosis: common psoriasis, plaque type, progressive stage, autumn-winter form. Sick for 15 years did not go to rest to the sea and generally tried not until yatsa on the people.

On the advice of a friend asked the club Sokolniki 7 to doctors dermatologists. Bought two packs of ointment “Antipsoriasis” and began regularly to apply it in the instructions. Spots began to disappear. To place plaques remained a slight redness, which eventually disappeared. For four months the patient got rid of the psoriasis.

Ointment for the treatment of psoriasis, characterized in that it contains aqueous extracts of Bidens tripartite (Bidens tvipartita), leaves of white birch (Betula alba L.), celandine (Chelidonium majus), calendula officinalis (Calendula officanalis L), marsh cudweed herb (Gnaphalium uliginosum) and oil extracts of the same plants, as well as the fatty phase, including medical petroleum jelly, lanolin, camphor, linseed oil and grease medical, in the following ratio, wt.%:

Aqueous extract of Bidens tripartite

(Bidens tvipartita) 0,1-2,9

Aqueous extract of birch leaves

white (Betula alba L) 0,1-3,5

Aqueous extract of celandine

(Chelidonium majus) 0,1-2,9

Aqueous extract of calendula

(Calendula officanalis L) 0,1-2,9

An aqueous extract of the marsh cudweed herb

(Gnaphalium uliginosum) of 0.1-2.0

Vaseline medical 0,1-2,0

Lanolin 1,1-5,0

Camphor 0.1 to 5.0

Flaxseed oil 0,9-1,0

The grease medical Rest,

the ratio in the aqueous and oil extracts of plants is 5:1.



 

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