Method for evaluating the volume and resistance in the structures of middle ear

FIELD: medicine.

SUBSTANCE: one should measure electric impedance of patient's middle ear. Electrodes should be applied in three localizations: auditory canal, anterior end of lower nasal concha and frontal skin. Electric impedance should be measured at the frequencies of sinusoidal signal being equal to 10, 30, 250 and 1000 Hz, the data obtained should be compared by values of electric impedance in the given area (middle ear) in the group of healthy patients. This method provides the chance to obtain comparative data for diagnostics of middle ear diseases.

EFFECT: higher accuracy of evaluation.

2 ex

 

The invention relates to medicine, namely to otorhinolaryngology. The classic way of impedancometry, the so-called acoustic impedancometry was developed O.Metz in 1946 [2]. Further, the method has undergone several improvements, the most important of which was to replace the Electromechanical principle of registration-acoustic [4]. The basis of the method is the registration of the acoustic resistance (impedance) of the middle ear, depending on the magnitude of the air pressure in the outer ear canal, expressed in mm vods This method was widely used in the clinic in the form of tympanometry and reception of the acoustic reflex.

There is a way of measuring the impedance characteristics of different biological structures, in particular the inner ear by electric impedancometry [3, 5]. These studies included experiments in hearing and has not found clinical application. By definition, the electrical impedance is the ratio of the voltage between the two contacts to the electric current flowing through them. Well-known various electronic circuit to measure the electrical impedance of biological structures 1.

The principle of operation of the device is as follows. Measuring electrodes attached to the biological object, represent one arm of the bridge. Two drugable in the scheme of fixed impedance. The fourth arm of the bridge is adjustable. From the oscillator electrical sinusoidal signal, and the detector in the diagram indicates an imbalance in the shoulders of the bridge. Adjusting the fourth shoulder, bring the bridge into balance all of his shoulders (zero potential in the circuit). The amount required to balance the bridge, and is the impedance of the measured object. Full dimension to produce different frequencies of sinusoidal signal. In addition, applying a phase-sensitive demodulator, can be distinguished in the output signal of the resistive and reactive (capacitive) components of the impedance of the object.

The closest solution is “a Method of predicting the course of encephalopathy diseases and injuries of the brain and a device for its implementation”, patent 02147830 from 27.04.2000, taken as a prototype. The method is performed by examining the anatomical state of the brain by the method of electromagnetopotential impedancometry at three frequencies with three inductive sensors. Impedance measurement performed both in pre - and postoperative periods. The obtained data are compared with the control measured in healthy people. With progressive reduction of the difference between the control parameters and the received data of the patient predicts favorable for encephalopathy. If you increase this difference, or it will postmasterdirect negative for BSE.

The above methods have their disadvantages.

For acoustic impedancometry this:

1. mandatory integrity of the eardrum;

2. the method allows to evaluate the status of the tympanic cavity;

3. the method does not always work in young children.

For the method electromagneticchannel impedancometry in respect of its application for authority hearing this:

1. disproportionately bulky for middle ear inductive sensors;

2. electromagnetic resonance of mixed bone and soft tissue structures, such as the middle ear, is not a physiological effect.

To address the shortcomings of the above clinical methods, a method of electric impedancometry in persons with diseases of the organ of hearing.

The purpose of the invention is to estimate the volume and the electrical impedance of the middle ear structures.

The method consists in the following. Subject patient to impose three electrodes. The electrode is a metal rod with a diameter of 1-2 mm, length 100 mm with thread on one end and soldered to the connecting wire on the other end. At the end of the thread wound with a cotton swab and moisten in physiological solution. One electrode is introduced into the ear canal investigated the ear, the other electrode is introduced into the corresponding cavity of the nose to tightly what about contact with the front end of the lower turbinate. The electrodes are held by placing their volume in the outer ear canal and the nasal cavity. The third electrode fixed with adhesive tape on the skin of the forehead.

Wire electrodes connected to the electric impedancometry. Measure the magnitude of the electrical impedance. Each measurement performed at different frequencies of sinusoidal signal, usually 10, 30, 250 and 1000 Hz. Record the magnitude of the electrical impedance at each measurement. Analysis of the results is to compare patient-derived data with previously obtained normative data in healthy persons Complied with all necessary rules for registration of electric potentials from the man at the application of non-invasive electrodes.

Positive effect: the possibility of application of the method without contraindications, research can be carried out in the early postoperative period, the possibility of conducting studies in patients of different age groups, taking into account the compactness of the device, it is possible to study not only at the bedside, but in the ENT departments of polyclinics.

Example 1. Extract from the patient card patient Khachaturian I. P., 26 years. Diseases of ENT-organs is not revealed. The result of research carried out by the proposed method at frequencies of 10, 30, 250 and 1000 Hz right ear - 45, 40, 20, 10 kω; left ear - 60, 50, 20, 10 kω with therefore, its.

Example 2. Extract from the patient card patient Epifanova the like, 50 years. Diagnosis: left tubolit. A study by the proposed method at frequencies of 10, 30, 250 and 1000 Hz: left ear - 260, 200, 100, 65 K, respectively, pathological changes on the part of the right ear was not detected.

Sources of information

1. Geddes LA, Baker LE Principles of Applied Biomedical Instrumentation // - 1968. Wiley. New York. 479 p.p.

2. Metz O. The acoustic impedance measured on normal and patological ears // Acta otolaryngol. 1946. Suppl. 63. p.1-254.

3. Misrahy G.A.., et al. Electrical properties of the wall ofendolymphatic space of the cochlea (guinea pig). // Amer. J. Physiol. 1958. v.194. p.396-402.

4. Terkildsen K., Nielsen, S.S. An electroacoustic impedance measuring bridge for clinical use // Arch. otolaringol. 1960. v.72. p.339-346.

5. von Bekesy G. Gross localization of the place of origin of the cochlear microphonics // J. Acoust. Soc. Amer. 1952. v.24. p.399-409.

The way to assess changes in the volume and resistance of the middle ear structures by measuring electrical impedance, characterized in that the electrodes are put in three locations: external auditory meatus, the front end of the lower turbinate and the skin of the forehead, while the electrical impedance is measured at frequencies of sinusoidal signal of 10, 30, 250 and 1000 Hz, the received data is compared by the values of the electrical impedance of this region (middle ear) the group of healthy individuals, which enables the compilation of summary data for the diagnosis of diseases of the middle ear.



 

Same patents:

FIELD: medicine.

SUBSTANCE: method involves carrying out urological examination for determining hydrodynamic resistance of ureter calculated from formula Z=8Lμ/(πR4), where Z is the hydrodynamic resistance of ureter, L is the ureter length, R is the ureter radius, μ is the urine viscosity. Angle α at which the ureter enters the urinary bladder is determined from formula cosα = 8l1μ/(ZπR4), where l1 is the perpendicular drawn from the upper edge of the ureter to the its exit projection line, μ is the urine viscosity, Z is the hydrodynamic resistance of ureter, R is the ureter radius. Vesicoureteral reflux recidivation is predicted when the angle of α+90° is less than 120°.

EFFECT: enhanced effectiveness in reducing the number of recidivation cases.

2 dwg, 1 tbl

The invention relates to medical equipment, namely to diagnostic devices for measuring impedance in specified parts of the body, and can be used for non-invasive determination of volumes of body fluids

The invention relates to medicine, namely to a gastroenterologist, and can be used for both adults and school-aged children
The invention relates to the field of veterinary medicine

The invention relates to animal husbandry

The invention relates to medicine, in particular to normal and clinical physiology

The invention relates to medicine, more specifically to a diagnostic electrode devices for measuring electrical impedance of body tissues

The invention relates to medicine, orthopedics

The invention relates to medicine, in particular for laboratory diagnosis

FIELD: medicine.

SUBSTANCE: method involves carrying out urological examination for determining hydrodynamic resistance of ureter calculated from formula Z=8Lμ/(πR4), where Z is the hydrodynamic resistance of ureter, L is the ureter length, R is the ureter radius, μ is the urine viscosity. Angle α at which the ureter enters the urinary bladder is determined from formula cosα = 8l1μ/(ZπR4), where l1 is the perpendicular drawn from the upper edge of the ureter to the its exit projection line, μ is the urine viscosity, Z is the hydrodynamic resistance of ureter, R is the ureter radius. Vesicoureteral reflux recidivation is predicted when the angle of α+90° is less than 120°.

EFFECT: enhanced effectiveness in reducing the number of recidivation cases.

2 dwg, 1 tbl

FIELD: medicine.

SUBSTANCE: one should measure electric impedance of patient's middle ear. Electrodes should be applied in three localizations: auditory canal, anterior end of lower nasal concha and frontal skin. Electric impedance should be measured at the frequencies of sinusoidal signal being equal to 10, 30, 250 and 1000 Hz, the data obtained should be compared by values of electric impedance in the given area (middle ear) in the group of healthy patients. This method provides the chance to obtain comparative data for diagnostics of middle ear diseases.

EFFECT: higher accuracy of evaluation.

2 ex

FIELD: medicine; medical engineering.

SUBSTANCE: method involves doing multi-channel recording of electroencephalogram and carrying out functional tests. Recording and storing rheoencephalograms is carried out additionally with multi-channel recording of electroencephalogram synchronously and in real time mode in carotid and vertebral arteries. Electroencephalograms and rheoencephalograms are visualized in single window with single time axis. Functional brain state is evaluated from synchronous changes of electroencephalograms, rheoencephalograms and electrocardiograms in response to functional test. The device has electrode unit 1 for recording bioelectric brain activity signals, electrode unit 2 for recording electric cardiac activity signals, current and potential electrode unit 3 for recording rheosignals, leads commutator 4, current rheosignal oscillator 5, synchronous rheosignal detector 6, multi-channel bioelectric brain activity signals amplifier 7, electrophysiological signal amplifier 8, demultiplexer 9, multi-channel rheosignal amplifier 10, multi-channel analog-to-digital converter 11, micro-computer 12 having galvanically isolated input/output port and personal computer 13 of standard configuration.

EFFECT: enhanced effectiveness of differential diagnosis-making.

11 cl, 6 dwg

FIELD: medical engineering.

SUBSTANCE: device has acting upon skin between electrodes with DC potential of given magnitude for producing temporary breakdown. Skin impedance is measured between measuring electrode first negatively polarized relative to control electrode and the control electrode, and then, DC current resistance is measured once more by means of measuring electrode positively polarized relative to the control electrode. Ratio of the obtained values is used for determining internal organ health state, corresponding to skin area.

EFFECT: enhanced accuracy of diagnosis.

11 cl, 14 dwg, 2 tbl

FIELD: poultry science.

SUBSTANCE: the present innovation deals with visual evaluation in chicken followed by testing them by the value of bioelectric potential. Chickens with bioelectric potential being significantly higher against average values are considered to be stress-resistant ones and those with bioelectric potential being significantly lower against average values in concrete population are concluded to be stress-sensitive ones. The method is very simple in its implementation and efficient for large-scale selection in poultry on stress-resistance.

EFFECT: higher efficiency.

1 cl, 2 dwg, 2 ex, 4 tbl

FIELD: medicine.

SUBSTANCE: the method deals with measuring geometric body size and electric impedances of patient's hands, body and legs at their probing with low- and high-frequency current due to current and potential electrodes applied onto distal parts of limbs, and, thus, detecting extracellular, cellular and total volumes of liquid in patient's hands, body and legs. While implementing the method one should additionally apply current electrodes onto left-hand and right-hand parts of neck, and potential electrodes - onto distal femoral parts. Body impedance (Zb) should be measured due to successive measuring the impedance of its right-hand Zrb and left-hand Zlb parts at probing current coming between electrodes of similar sides of patient's neck and legs to detect Zb, as Zb = Ѕ x (Zrb + Zlb), impedance of legs Zl should be detected due to measuring femoral impedance Zf and that of shins Zs, as Zl = Zf + Zs. At detecting the volumes of liquid in body and legs one should apply measured values of Zb and Zl, moreover, as geometric body size one should apply the distance against the plane coming through the upper brachial surface up to the middle of radiocarpal articulation in case of patient's hand being along the body.

EFFECT: higher accuracy of detection.

5 dwg, 2 ex, 3 tbl

FIELD: medicine; medical engineering.

SUBSTANCE: method involves applying electrodes to injured extremity tissue under study. The electrodes are arranged in diametrically opposite points of horizontal plane transaction to extremity surface. Two electrodes are applied to the other extremity. The electrodes are arranged in diametrically opposite points of horizontal plane transaction to extremity surface. An initial point is selected relative to which pairs of electrodes are equidistantly arranged on the extremity. Active and reactive impedance components are measured at the places of electrodes positioning. Viability condition of the injured extremity tissue under study is diagnosed depending on ratio of reactive to active impedance component on injured and intact extremity and difference between reactive impedance component on injured and intact extremity. Device has transducer unit, computer and unit for processing signals having interface units, central subscriber station, autonomous transmission center, commutator which input is connected to transducer unit output and commutator output is connected to central subscriber station input, the first input is connected to autonomous transmission center output.

EFFECT: high accuracy in diagnosing biological object condition.

5 cl, 5 dwg, 4 tbl

FIELD: medicine, psychotherapy.

SUBSTANCE: the method deals with correcting neurological and psychopathological disorders with anxiety-phobic symptomatics due to individual trainings. The method includes evaluation of body reaction to stimulating signals, seances of individual training performed due to the impact of two quasiantipodal stimulating signals of similar physical modality applied in time of sporadic character, and as a signal one should present biological feedback for the altered value of physiological parameter adequately reflecting body reaction to the impact of stimulating signal. At the first stage of training it is necessary to achieve body adaptation to the impact of quasiantipodal stimulating signals, at the second stage it is necessary to obtain conditional reflex for one out of stimulating signals, for this purpose one should accompany this stimulating signal with discomfort impact, during the third stage, finally, due to volitional efforts one should suppress body reaction to stimulating signal. The devise suggested contains successively connected a transformer of physiological parameter into electric signal and a bioamplifier, an analysis and control block with a connected block to present the signals of biological feedback, a block for presenting discomfort impact, an indication block and that of forming and presenting quasiantipodal stimulating signals. The innovation enables to have skills to control one's emotions, decrease sensitivity threshold to environmental impacts and learn to how behave during stress situations.

EFFECT: higher efficiency of training.

15 cl, 8 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves recording multichannel electroencephalogram, electrocardiogram record and carrying out functional test and computer analysis of electrophysiological signals synchronously with multichannel record of electroencephalogram and electrocardiogram in real time mode. Superslow brain activity is recorded, carotid and spinal artery pools rheoelectroencephalogram is recorded and photopletysmogram of fingers and/or toes is built and subelectrode resistance of electrodes for recording bioelectrical cerebral activity is measured. Physiological values of bioelectrical cerebral activity are calculated and visualized in integrated cardiac cycle time scale as absolute and relative values of alpha-activity, pathological slow wave activity in delta and theta wave bandwidth. Cerebral metabolism activity dynamics level values are calculated and visualized at constant potential level. Heart beat rate is determined from electrocardiogram, pulsating blood-filling of cerebral blood vessels are determined from rheological indices data. Peripheral blood vessel resistance level, peripheral blood vessel tonus are determined as peripheral photoplethysmogram pulsation amplitude, large blood vessel tonus is determined from pulse wave propagation time data beginning from Q-tooth signal of electrocardiogram to the beginning of systolic wave of peripheral photoplethysmogram. Postcapillary venular blood vessels tonus is determined from constant photoplethysmogram component. Functional brain state is determined from dynamic changes of physiological values before during and after the functional test. Device for evaluating functional brain state has in series connected multichannel analog-to-digital converter, microcomputer having galvanically isolated input/output ports and PC of standard configuration and electrode unit for reading bioelectric cerebral activity signals connected to multichannel bioelectric cerebral activity signals amplifier. Current and potential electrode unit for recording rheosignals, multichannel rheosignals amplifier, current rheosignals generator and synchronous rheosignals detector are available. The device additionally has two-frequency high precision current generator, master input of which is connected to microcomputer. The first output group is connected to working electrodes and the second one is connected to reference electrodes of electrode unit for reading bioelectrical cerebral activity signals. Lead switch is available with its first input group being connected to potential electrodes of current and potential electrodes unit for recording rheosignals. The second group of inputs is connected to outputs of current rheosignals oscillator. The first group of outputs is connected to current electrodes of current and potential electrodes unit for recording rheosignals. The second group of outputs is connected to inputs of synchronous detector of rheosignals. Demultiplexer input is connected to output of synchronous detector of rheosignals and its outputs are connected to multichannel rheosignals amplifier inputs. Outputs of multichannel bioelectrical cerebral activity signals amplifier, multichannel rheosignals amplifier and electrophysiological signal amplifier are connected to corresponding inputs of multichannel analog-to-digital converter. Microcomputer outputs are connected to control input of lead switch, control input of multichannel demultiplexer, control input of multichannel analog-to-digital converter and synchronization inputs of current rheosignals oscillator and synchronous detector of rheosignals. To measure subelectrode resistance, a signal from narrow bandwidth current generator of frequency f1 exceeding the upper frequency fup of signals under recording is supplied. A signal from narrow bandwidth current generator of frequency f2≠ f1>fup is supplied to reference electrode. Voltages are selected and measured at output of each amplifier with frequencies of f1, f2 - Uf1 and Uf2 using narrow bandwidth filtering. Subelectrode resistance of each working electrode is determined from formula Zj=Ujf1 :(Jf1xKj), where Zj is the subelectrode resistance of j-th electrode, Ujf1 is the voltage at output from j-th amplifier with frequency of f1, Kj is the amplification coefficient of the j-th amplifier. Subelectrode resistance of reference electrode is determined from formula ZA=Ujf2 :(Jf2xKj), where ZA is the subelectrode resistance of reference electrode, Ujf2 is the voltage at output from j-th amplifier with frequency of f2, Jf2 is the voltage of narrow bandwidth current oscillator with frequency of f2.

EFFECT: wide range of functional applications.

15 cl, 10 dwg

FIELD: medical engineering.

SUBSTANCE: device has divider, comparison unit, oscillator, acoustic radiator, controllable current source, stable constant voltage source, perspiration equivalent unit, key member, illumination source, conductivity transducer having two electrodes, the first commutator, delay unit, trigger, inverter, discharge unit, the second commutator and feeding voltage availability indicator unit. The first delay unit inputs and the first commutator inputs are connected to comparison unit output. The first commutator input is connected to the first oscillator input which delay unit, trigger and inverter are connected in series. Inverter output is connected to the second input of the first and the second commutator. The first input of the second commutator is connected to the other conductivity transducer electrode and its output is connected to device body via resistor.

EFFECT: reduced current intensity passing through patient skin; excluded negative influence upon skin during prolonged operation time on patient arm during hypoglycemia attack; low power consumption.

2 cl, 4 dwg

Up!