Method for treating skin diseases
SUBSTANCE: the present innovation deals wit treating and preventing skin diseases. One should treat the focal surface with the ointment based upon an antiseptic Dorogov's stimulant followed by intravenous injections of sodium thiosulfate solution and restorative therapy. Moreover, this ointment contains birch oil, ichthyol and lubricant grease. As restorative therapy one should prescribe the tincture of medicinal plants species. This method provides more stable remission.
EFFECT: higher efficiency of therapy.
1 cl, 2 ex
The invention relates to medicine, namely to methods of treatment and prevention, and is intended for the treatment of skin diseases.
It is known that the treatment of skin diseases, including psoriasis, eczema, dermatitis, various forms diathesis is an extremely difficult and lengthy process. It usually includes a complex effect: conducting detoxification and recreation activities, as well as specific treatment. Traditionally used sodium thiosulfate, providing desensitizing, anti-inflammatory and antitoxic action (see, for example, RU 2154480 C1, Hajicova and others, 20.08.2000; EN 2195299 C2, Kleimenova and others, 27.12.2002). For example, in the treatment of trophic ulcers (EN 2121841 C1, Starchenko and others, 20.11.1998) the patient is prescribed a 30%sodium thiosulfate as desensitization means, ointments, methylxanthines, antispasmodics, injections of ascorbic acid, and vitamins b6and PP.
As adaptogene in skin diseases of different etiology known application of antiseptic, stimulant Dorogov - drug DCA fractions 2 and 3 as both internal and external funds (see SU 130857, roads, 16.01.70; literature review in the description of the invention EN 2159116 C1, Dorogov, 20.11.2000). The drug DCA-3 is assigned externally as in pure form and in the form of 1-50%of the energy ointments and pastes (Mashkovsky PPM Drugs is a war funds ed. 12, Rev. and ext., 1993, volume 2, z).
In the complex therapy of skin diseases are also agents of vegetable origin. So for the treatment of seborrheic skin diseases (dermatitis, eczema) described the use of medicinal plants in the form of a tincture for intake, and alcohol rubs, while maintaining diet (EN 2209632 C1, Korsun, and others, 10.08.2003). Infusion for internal reception includes herbs - marjoram, hop cones, root calamus swamp, plantain leaves, chicory roots and elecampane, and for outdoor use recommended alcoholate, including grass yarrow and horsetail.
Closest to the invention is a method of treatment of skin diseases (EN 2210374 C1, Scrapers, etc., 20.09.2003), in which the use of the intravenous infusion of 30%sodium thiosulfate, alternating ointments, including on the basis of 2%of the drug ASD (without specifying fractions) with the addition of siliceous sludge of Tripoli.
The objective of the invention is to increase the efficiency of treatment by optimizing the composition of ointments, as well as the use of infusions fees of a number of medicinal plants, normalizing metabolism and promote regenerative processes on the skin.
Technical result - providing a stable remission when using non-deficient medic the cops and traditional medicine drug without overloading the body, is achieved by a method for the treatment of skin diseases includes processing the surface of the hearth ointment on the basis of antiseptic, stimulant Dorogov - drug ASD, intravenous infusion of sodium thiosulfate and restorative therapy.
The ointment contains the drug ASD in the form of fractions 2 and 3 and additionally birch tar, Ichthyol and grease with the following content of components, parts by weight:
the drug DCA fraction 2 10-30
the drug DCA fraction 3 30-70
Birch tar 20-30
The Ichthyol 8-12
The grease 70-90
When sodium thiosulfate is administered in the form of a 10%-aqueous solution in the amount of 10-15 cm3within 15-21 days. As a restorative therapy is prescribed phyto - infusion collection of medicinal plants, including immortelle, Jerusalem sage, chestnut Crimean, agrimony, hodgepodge Holloway, yarrow herb, chicory root, a succession of grass, with the following content, wt. including:
The Jerusalem sage 30-40
Chestnut Crimean 40-45
Salsola Collina 45-50
Yarrow herb 55-65
Chicory root 35-45
A series of grass 25-35.
The method can be characterized by the fact that extra hold oral infusion collection containing alfredia wilting, leaf weeping birch, Vodyanik bald mountain, the root galichnik of Morison, the root of the elecampane, St. John's wort, Cladonia, is nazek Siberian, the peony, cleaver, greater celandine, a series of tripartite, horsetail, schizonepeta mnogodetnoy, taken in an amount of 2-4 parts, 1/3 Cup 30 minutes before meals, 3 times a day for 45 days.
The treatment begins with a deep cleansing of the intestine daily for 7-10 days. For normalization of intestinal flora can be recommended intake of lactobacilli in the morning, the number of 4-6 doses. In addition, the assigned diet: boiled chicken meat and sea fish, boiled vegetables, porridges on water, compote of dried fruits, fresh vegetable juices. Exclude from the menu, milk, eggs, meat and meat products, sweets, coffee, cocoa, pastries and dishes made from white flour.
Sodium thiosulfate in the form of a 10%solution intravenously injected in the amount of 10-15 cm3within 15-21 days, using the significantly lower concentration than the nearest equivalent (30%).
Ointment on the basis of ready-made forms of drugs SDA 2 and SDA-3 with the addition of birch tar, Ichthyol and grease is prepared in a traditional way. It is recommended to lubricate the affected area 1-2 times a day. When processing on the night of ointment applied under compress paper.
As a restorative therapy is prescribed phyto - infusion collection of medicinal plants, including immortelle, Jerusalem sage, chestnut Crimean, agrimony, hodgepodge Holloway, thousands of listrik grass, chicory root, string grass. Phyto-infusion prepared immediately before use like regular tea. One teaspoon with the top collection pour 200 ml boiling water, mix, cover and infuse for 10-15 minutes drink hot and fresh.
As an additional healing tools can be used infusions fees medicinal plants from the series “Altai medical fees” (http://www.altai-balzam.ru/fitosb05.htm), for example, collection No. 44. These fees improve carbohydrate, lipid, protein, enzyme metabolism, reduce autoimmune processes. Fees have analgesic, anti-inflammatory, anti-allergic, antiseptic action. Used infusion collection, containing 2-4 h: alfredia wilting, leaf weeping birch, Vodyanik bald mountain, the root galichnik of Morison, the root of the elecampane, St. John's wort, Cladonia, knezek Siberian, the peony, cleaver, greater celandine, a series of tripartite, horsetail, schizonepeta mnogodetnoy. When using 1 table spoon collection pour a glass of boiling water in thermos in the evening, in the morning - filter. Take 1/3 Cup 30 minutes before meals, 3 times a day for 45 days.
Patent-pending method of complex treatment of chronic skin diseases helps to achieve remission when using the non-deficient medicines and traditional medicines drug without overloading the body (sodium thiosulfate is used in a concentration of 3 times smaller than the equivalent).
Example 1. Patient L.V., 32 years. Entered in August 2003 with complaints of itching and skin rashes. Considers himself to be patient since childhood, when he was first diagnosed with diathesis. Further repeatedly treated in ARCS about atopic dermatitis. Used antihistamines (suprastin, fenkarol), calcium gluconate, ointments with corticosteroids. The effect was negligible, and remission is short. Improvement was noted in the summer months after insolation. On examination, the skin of the neck, flexor surfaces of the upper and lower extremities, there are lots of lichenization with multiple excoriation due to scratching. Diagnosis: atopic dermatitis.
The patient was assigned to deep cleansing of the intestine daily for 10 days with simultaneous reception of lactobacilli in the morning of 5 doses. A diet with a high content of chicken meat and with the exception of milk, sweets, coffee, cocoa, serving from white flour. Intravenous she received a 10%solution of sodium thiosulfate and 10 cm3daily for 15 days. Topically on the affected skin with a thin layer was applied the ointment containing the drug DCA fraction 3 (SDA-3) - 7 h, grease - 9 h, the drug DCA fraction 2 (ASD-2) 3 h, birch tar, 2 h, Ichthyol - 1 h Drug DCA-2, ASD-3 was used in the form of ready-made forms. The patient has a herbal tea - this is the collection of medicinal plants (contains immortelle, the Jerusalem sage, chestnut Crimean, agrimony, hodgepodge Holloway, yarrow herb, chicory root, string grass) within 60 days.
On the 6th day from the beginning of treatment showed a significant improvement of the skin: decreased itching the affected areas was noticeably pale, decreased licensure. The patient is additionally assigned oral infusion of herbs containing alfredia wilting, leaf weeping birch, Vodyanik bald mountain, the root of the elecampane, St. John's wort, Cladonia, the peony, cleaver, greater celandine, a series of tripartite, horsetail, 1/3 Cup 3 times a day for 30-40 minutes before a meal within 45 days.
When viewed on the 20th day of treatment: the condition has improved significantly, skin itching no worries, lots of lichenization almost completely resorbed, restored elasticity and splint skin. The condition is clinical remission. Recommended dynamic observation.
Example 2. Patient A.R., 43 years old, was admitted 20.10.2003 years diagnosed with widespread psoriasis, progressive stage. Sick since 1999, when after car crash appeared rash on the abdomen, lumbar region, scalp, knees and elbows. Observed in the ARC at the place of residence. In October 2001 he passed a course of PUVA therapy in clique. Remission until November 2002. is ostrinia occurred in early autumn. On examination: skin, breast, belly and back there are multiple lesions in the form of plaques rich red-purple color with a diameter from 6 to 20 cm with flaking on the surface. In the legs rashes are grouped in plots with palm. On elbows and knees - "on duty" plaques. Rashes on the scalp according to the type of "corona psoriaticum". Psoriatic triad - positive. RV - negative.
The patient is assigned profound colon cleansing in the number of 7 daily sessions; intravenous 10%solution of sodium thiosulfate and 15 cm3within 20 days.
Externally on the affected areas of skin 2 times a day (in the evening under compress paper) was applied ointment containing ASD fraction 3 (SDA-3) 3 h, the grease 7 h, the drug DCA fraction 2 (ASD-2) - 1 h, birch tar, 3 h, Ichthyol - 1 h also appointed phyto - infusion of medicinal plants (immortelle, Jerusalem sage, chestnut Crimean, agrimony, hodgepodge Holloway, yarrow herb, chicory root, string grass) within 60 days.
When viewed on the 10th day from the start of treatment, there is a positive dynamics of the process of the skin: practically disappeared peeling, paint the plaques became much lighter, significantly decreased their infiltration. The patient is advised to take extra oral infusion of medicinal herbs 1/2 Cup 3 times what a day for 30-40 minutes before meals. When viewed on a 20-day treatment: the condition has improved significantly, and new lesions do not appear, small plaques disappeared completely, is a minor redness large pockets and "duty" plaques. The patient is assessed as clinical remission.
1. The method of treatment of skin diseases, including the treatment of the surface of the hearth ointment on the basis of antiseptic, stimulant Dorogov - drug ASD, intravenous infusion of a solution of thiosulfate and restorative therapy, characterized in that the ointment contains the drug ASD in the form of fractions 2 and 3 and additionally birch tar, Ichthyol and grease, with the following content of components, parts by weight:
the drug DCA fraction 2 10-30
the drug DCA fraction 3 30-70
birch tar 20-30
the Ichthyol 8-12
the grease 70-90,
sodium thiosulfate is administered in the form of a 10%solution in the amount of 10-15 cm3within 15-21 days, and as a restorative therapy is prescribed phyto - infusion collection of medicinal plants, including immortelle, Jerusalem sage, chestnut Crimean, agrimony, hodgepodge Holloway, yarrow herb, chicory root, a succession of grass, with the following content of components, parts by weight:
the Jerusalem sage 30-40
chestnut Crimean 40-45
Salsola Collina 45-50
yarrow Tr the VA 55-65
chicory root 35-45
a series of grass 25-35.
2. The method according to claim 1, characterized in that it further conduct oral infusion collection containing alfredia wilting, leaf weeping birch, Vodyanik bald mountain, the root galichnik of Morison, the root of the elecampane, St. John's wort, Cladonia, knezek Siberian, the peony, cleaver, greater celandine, a series of tripartite, horsetail, schizonepeta mnogodetnoy, taken in an amount of 2-4 parts, 1/3 Cup 30 minutes before meals 3 times a day for 45 days.
FIELD: medicine, pharmacology, pharmacy.
SUBSTANCE: invention proposes an agent for treatment of infected wounds that comprises zeolite of Kcholinskiy deposit that represents zeolite powder modified with silver with particles size 17-20 . The proposed form provides enhancing the curative effect of agent due to elevating porosity of zeolite and increasing area in interaction of precipitated silver with wound surface. Invention can be used in surgery for healing wounds, among them chronic sluggish wound and trophic ulcers showing refractory properties to treatment with conventional agents.
EFFECT: improved and valuable properties of agent.
1 tbl, 7 ex
SUBSTANCE: method involves using air-dried vegetable raw. Hollow horse-mint (Monarda) raw treated by steam is extracted with vegetable oil in the ratio raw : extract = 1:10 at heating for 5 h on water bath at temperature 60-70oC followed by filtration. Method provides the possibility for year-round manufacturing the hollow horse-mint (Monarda) oily extract eliciting with the high antibacterial and expressed anti-fungal activity.
EFFECT: improved preparing method.
1 tbl, 1 ex
FIELD: organic chemistry, medicine.
SUBSTANCE: invention proposes new compounds of the general formula (I):
wherein R1 means one or more similar or different substitutes taken among the group consisting of hydroxy-group, halogen atom including F, Cl, Br and J, (C1-C5)-alkyl, (C1-C5)-alkoxy-group under condition that when R1 means one substitute then it is in ortho-position and when R1 means above one substitute then at least one substitute at R1 is in ortho-position; R2 means halogen atom including F, Cl, Br and J, (C1-C5)-alkyl, (C1-C5)-alkoxy-group; R3 means halogen atom including F, Cl, Br and J; R6 means hydrogen atom or methyl; and its salts with pharmaceutically acceptable acids, hydrates or solvates. Compounds elicit activity against acne and acne-related diseases.
EFFECT: valuable medicinal properties of compounds.
7 cl, 4 tbl, 43 ex
FIELD: chemical and pharmaceutical industry.
SUBSTANCE: the present innovation deals with creating medicinal preparations of plant origin and could be applied for treating functional constipations and affected biorhythm of defecation. It is suggested to apply either dry aqueous or aqueous-alcoholic extract of horse chestnut seeds of Aesculus species to prepare curative-prophylactic preparation in case of constipation and affected biorhythm of defecation. The suggested preparation should be applied in the form of powder, tablets or suppositories. Pharmaceutical composition for preventing and treating constipation and affected biorhythm of defecation contains an active substance out of medicinal plant and a pharmaceutically acceptable filling agent, moreover, this preparation is designed as suppositories and contains either dry aqueous or aqueous-alcoholic extract of horse chestnut seeds of Aesculus species and suppository hydrophobic foundation at certain content of ingredients. Dry aqueous or aqueous-alcoholic extract contains 1-50% active substance as escin. As foundation it could contain either cacao oil or vitepsol. The method for preventing and treating constipations and affected biorhythm of defecation deals with introducing the suggested pharmaceutical composition into patient's anus 5-15 min before planned act of defecation. Application of "Rectum-activ" preparation provides positive result at treating functional psychogenic constipation: in 5-15 min after introducing a suppository into anus pronounced urgency for defecation. In case of course therapy for 4 wk one should observe restoration of natural urgency for intestinal evacuation. Moreover, purgative preparation causes no unfavorable pain feelings.
EFFECT: higher efficiency.
10 cl, 6 ex
FIELD: medicine, surgical gastroenterology.
SUBSTANCE: as a curative preparation one should apply a pectin-containing powder product of table beet out of sublimated raw material. For reducing the powder before application one should apply low-mineralized low-alkaline amicrobial solution of electrochemically activated catholyte. Supernatant transparent fraction of this solution should be constantly introduced by drops into nasobiliary probe, residual fraction should be applied for peroral additional enterosorption. The method provides sanitation of biliary ducts by preventing duodenocholedochous reflux, and enterosorption that decreases portal toxemia.
EFFECT: higher efficiency of therapy.
2 cl, 1 ex
FIELD: medicine, surgery.
SUBSTANCE: the present innovation deals with treating "surgical" endotoxicosis, peritonitis, in particular. For this purpose one should apply powder product of table beet obtained out of sublimated raw material. Since the 1st d after operation one should perform enteral introduction of homogenized aqueous suspension of the product at 20 g dry matter/300 ml drinking water of 18-22 C into nasointestinal probe, after intraoperational washing small intestine. Introduction should be carried out thrice daily, 3-5 d/course. The method provides simultaneous enterosorption, stimulation of intestinal motor system and nutritive support.
EFFECT: higher efficiency of therapy.
23 cl, 8 dwg, 1 ex, 5 tbl
FIELD: medicine, gastroenterology.
SUBSTANCE: one should apply food additives as tablets of oats, corn and cabbage by "Biophyt" company; moreover, to decrease motor system of biliary ducts one should apply tablets of oats, to increase motor system - tablets of corn and for total normalization of kinetics - tablets of cabbage. Treatment lasts for 10 d at the dosage of 1-2 tablets twice daily 30 min meals. The present innovation enables to normalize functional activity of biliary ducts at the background of shortened therapeutic terms.
EFFECT: higher efficiency of therapy.
SUBSTANCE: biologically active additive has propolis and pot marigold tincture, ascorbic acid, calcium gluconate, benadryl, rutin and auxiliary substances like starch, calcium stearate, talc taken in known proportion. The biologically active additive is produced as tablets of mass 0.55 g.
EFFECT: enhanced effectiveness of prophylaxis.
FIELD: medicine, obstetrics, gynecology.
SUBSTANCE: rehabilitation should be carried out in the third trimester of pregnancy based upon dispensary situated in ecologically safe region, as an enterosorbent one should apply "Carbopect" preparation per 0.5-0.6 g once daily for 3 wk; as an iodine preparation it is necessary to prescribe "Potassium iodide" 200 mcg once daily till the end of pregnancy period and during the whole period of lactation; as adaptogens one should additionally prescribe "Revit" per 2 lozenges thrice daily for 2 wk; vitamin-containing tea; one should, also, apply aerotherapy named "mountain air" per 15-40 min, 15 procedures, totally. The present innovation enables to improve anthropometric parameters in neonatals, decrease the percentage of complications in babies in early neonatal period, among them those that require antibioticotherapy.
EFFECT: higher efficiency of rehabilitation.
FIELD: medicine, cosmetology.
SUBSTANCE: one should restore and strengthen lipid epidermal barrier, activate metabolic processes in skin cells and protect skin against damaging factors by applying sea buckthorn lipids, moreover, before restoring and strengthening lipid epidermal barrier one should additionally purify the skin deeply against contamination and sebum; moreover, the above-mentioned stages of restoration and strengthening lipid epidermal barrier, activation of metabolic processes in skin cells and its protection against damaging factors should be carried out successively, moreover, activation of metabolic processes in skin cells should be performed by applying a preparation containing sea buckthorn and cedar lipids at their ratio being 0.5 - 1.5, correspondingly. Moreover, deep skin purification against contamination and sebum should be conducted by applying a preparation containing cedar lipids. Moreover, restoration and strengthening of lipid epidermal barrier should be performed with a preparation containing sea buckthorn lipids, and skin protection against damaging factors - with a preparation containing cedar lipids.
EFFECT: higher efficiency of skin aging prevention.
3 cl, 3 ex
FIELD: food industry.
SUBSTANCE: invention relates to biologically active additives containing carbohydrate syrups and provides biologically active additive based on plant Comarum palustre L. Additive is prepared in the from of in the form of syrup and contains aqueous extract of Comarum palustre L. Extract is obtained by infusion of broken raw material for 20 h at 80-90оС and raw material-to-water ratio 1:10. Additive further includes citric acid, sorbic acid, and sugar at specified proportions. Additive can be used as preventive health-improving agent in cases of elevated loadings on locomotor system as well as in cases of such diseases osteochondrosis, gout, rheumatism, polyarthritis.
EFFECT: enhanced preventive and healing effect.
FIELD: medicine, phytotherapy, pharmacy.
SUBSTANCE: invention relates to preparations of vegetable origin. Invention proposes the preparation eliciting immunomodulating effect and comprising aqueous-alcoholic extracts of the following plants, mas. p. p.: glabrous licorice roots, 5.0-15.0; fenestrate Saint-John's-wort herb 4.0-16.0; dandelion roots, 4.0-16.0; sandy immortelle flowers, 3.5-14.0; senna leaves, 3.5-14.0; thyme herb, 1.0-4.0; snowdon rose (rosewort) rhizomes and roots, 0.05-0.2. Also, invention proposes the preparation comprising condensed or an aqueous-alcoholic extract of above said plants and a filling agent. The preparation can be made as tablet or capsule. The preparation normalizes the blood free radicals content and provides elevating level of T-suppressors with the simultaneous reducing amount of T-helpers in blood of patients in treatment of acute and chronic inflammatory diseases of breathing organs.
EFFECT: valuable medicinal properties of preparation.
2 cl, 3 tbl, 1 ex
FIELD: medicine, virology, pharmaceutical industry, pharmacy.
SUBSTANCE: invention proposes the preparation used for treatment of viral hepatitis C that comprises birch bark extract with the content of betulin above 70% and a pharmaceutically acceptable carrier. The preparation is administrated to patient by oral route. The preparation promotes to the effective treatment of viral hepatitis C. Invention can be used in treatment of viral hepatitis C.
EFFECT: valuable medicinal properties of agent.
4 cl, 2 tbl
SUBSTANCE: the present innovation includes synthetic zeolite Na-A, sulfur and flavoring at the following ratio of components, weight%: sulfur 0.03-0.08, flavoring 1.0-1.5, synthetic zeolite Na-A - the rest. As flavoring one should apply food flavorings with the odor of vanillin, lemon, prune, almond, coffee. Organoleptic evaluation of preparation's properties has shown that it causes no irritation of human hand skin: hands become dry and demonstrate pleasant odor. Due to supplementing sulfur the suggested preparation provides elimination of harmful microflora, protects hand skin against infection. Preparation is simple to be manufactured and applied along with its low price and ecological safety.
EFFECT: higher efficiency.
1 cl, 1 tbl