Method for treating hypercholesterolemia in patients with cardio-vascular diseases

FIELD: medicine, cardiology.

SUBSTANCE: the present innovation includes hypolipidemic diet. Additionally, in the state of meditation one should induce the feeling of thermal disposition in intestinal area due to autosuggestion spirally starting from dextral ileal area and performing about 3-5 circles clockwise, only by narrowing the radius of movement towards navel's area, then about 3-5 circles clockwise by widening the radius of movement against initial circumference. Then one should similarly work with feelings of colic pains and cold. Moreover, autosuggestive impact should be carried out twice daily for 30-40 d, and then - once daily every other day to maintain cholesterol level at normal value. The method enables to treat hypercholesterolemia in patients despite cholesterol level.

EFFECT: higher efficiency of therapy.

1 cl, 1 tbl

 

The invention relates to medicine.

Cardiovascular disease, especially coronary heart disease and hypertension are common and relate to adverse prognostic diseases and occupy the first place among the causes of disability and death in Russia and most countries of the world (Diamonds V.A. et al. 1988, 1992; who, 1988, 1997; Mazur N.A., 1986; Shestov DB, 1985; Tagiev MS and al., 1995, 1999, 2000, 2002). Mortality from cardiovascular diseases in the CIS countries is about 50% of the total mortality and tends to increase (Virganskaya I.M. and others, 1993; Oganov RG, 1990). One of the reasons of reduction of the lumen of blood vessels is the defeat of the arteries with atherosclerosis formation in the walls of atherosclerotic plaques (Mazur N.A., 1986; Lipovetsky BM, Konstantinov V.O., 1993).

It is now established that among the many risk factors for the development of atherosclerosis is one of the first places is high blood cholesterol (hypercholesterolemia) and its major vector - density lipoprotein. The risk of developing atherosclerosis and its main clinical manifestations increases with increased level of cholesterol, especially when the cholesterol concentration greater than 5.2 mmol/l (200 mg/DC). It is proved that the level of Palestrina and the risk of development of ischemic pain is FDI heart especially myocardial infarction, there is a direct relation (Grandy S.M., 1986; Martin M.J. et al., 1986). This dependence has also been shown in Meminjamkan the study, which lasted for more than 30 years. The risk of coronary heart disease is gradually increased, starting from the level of cholesterine the 4.65 mmol/l (Neaton J.D. et al., 1984). The risk increases dramatically when the cholesterol level rises above the 5.7-6.2 mmol/l and increased 4-fold at the level of 6.7 mmol/l and above. There is also an inverse relationship between the level of cholesterol in the blood and the age at which we should expect the development of coronary heart disease. The calculations showed that every 1.3 mmol/l cholesterol shift the critical age for the development of coronary heart disease for 10 years. When cholesterol by 12.9 mmol/l and above myocardial infarction often revealed in youth and even children.

To date, there are numerous drug and non-drug methods of treatment of hypercholesterolemia. When pharmacological treatment, primarily using drugs that reduce the level of cholesterol in the blood (Pozdnyakov, Y.M., V.S. Volkov, 1997; Metelitsa V.I., 1999; Konstantinov V.O., 1999). Lipid-lowering means (Cholesterin, Niacin, Simvastatin, Lovastatin, Colestipol, and others) used long-term, Positano, as is they do not eliminate the cause of hypercholesterolemia. However, most of these tools has a damaging effect on the body it is when long their application. In addition, when short-term cancellation of many lipid-lowering drugs dramatically increases the level of cholesterol and triglycerides in the blood (Pozdnyakov, Y.M., V.S. Volkov, 1997; Konstantinov V.O., 1999). The cost of modern treatment of lipid-lowering drugs high enough (month course of treatment with Lovastatin or Simvastatin costs approximately 25.5 USD).

Patients with high hypercholesterinemia currently used correction of hyperlipidemia through some in vitro methods of purification of blood plasma (hemosorption, plasmapheresis and immunoadsorption). These methods are mainly applied for tertiary prevention of coronary heart disease. With the help of hemosorption from the body removes excess cholesterol through repeated perfusion of the patient's blood through carbon sorbents (Lopukhin, Y.M., Molodenkov M.N., 1985; Lopukhin, Y.M. et al., 1986). When the session duration of hemosorption 60-90 min and repeat procedures after 6-7 days have the opportunity to correct the disturbed lipid composition of blood plasma and significantly reduce the frequency of angina attacks (Lopukhin, Y.M. et al., 1986). However, after the termination of sessions of hemosorption 4-6 weeks the level of cholesterol reaches the initial level (Lopukhin, Y.M. et al., 1986). And therefore the need for repeat procedures. Plasmapheresis cholesterol is reduced through the substitution of plasma albumin (4 %). Plasmapheresis reduces the level of Palestrina 50 % and more. In some cases, prolonged 2-year use of plasmapheresis is possible to achieve regression of atherosclerotic plaques. Angina can get pretty long-term remission in the disease, to relieve the patient sometimes months from angina attacks. Especially these results can be obtained with severe angina resistant to a specific drug therapy. However, this method has some limitations, since prolonged use can lead to the loss of patients immunoglobulins and coagulation factors (Kukharchuk V.V. et al., 1986; Kukharchuk CENTURIES, 1994). Method immunosorption using special columns with antibodies to APO-beta-containing mannoproteins allows you to selectively remove only the atherogenic low-density lipoproteins. Clinical trials of this method has shown its good performance only for a certain period of time (Kukharchuk CENTURIES, Arabidze GG, 1986). These treatment methods are rather time-consuming, expensive, not safe (blood methods). When conducting enter the sorption as sorbents use coal, crystal microcellulose, dextran etc. (Ryzhenkov, V.E. et al., 1994). The approaches to gene therapy of hyperlipidemia (Pozdnyakov, Y.M., V.S. Volkov, 1997). However, these methods are also time consuming and expensive.

There are surgical methods of dealing with hyperlipidemia - different ways to bypass the small intestine (Miettinen T.A., Lempinen M., 1977, Denisenko A.D. and others, 1995). They also give a good but temporary hypocholesterolemic effect. Surgical methods are traumatic, not safe for the patient and costly.

Thus, all medical methods of treatment of hypercholesterolemia along with their inherent disadvantages (invasiveness, complexity, syndrome, high cost) have only a temporary effect.

Known non-pharmacological treatment of hypercholesterolemia by assigning special diets (who, 1993). The basis of lipid-lowering diet are the following provisions: a calorie restriction diet from fat, sugar, and alcohol; the decrease in food saturated fatty acids up to 7-10 % of the total caloric intake; reducing cholesterol levels of 200 to 250 mg per day; the ratio of polyunsaturated to saturated fatty acids should be in the range of 0.8/1; increase consumption of foods rich in vegetable proteins; limiting consumption Legkov aamah carbohydrates. Physiological need the calories for each person is determined in the diet, which does not cause changes in the body weight compared to normal. Treatment of lipid-lowering diet should be continued for at least six months. Lipid-lowering diet events compared with medical therapy are safe and economical. However, the diet of any duration effective only if the level of cholesterol in the blood not higher than 6.5 mmol/l In patients with high cholesterol (>6.5 mmol/l) even the most strict diet has virtually no effect on its level (Pozdnyakov, Y.M., V.S. Volkov, 1997). In this case, you must use medical methods of treatment.

The aim of the invention is to increase the effectiveness of treatment.

This is achieved by the fact that in addition to gipolipidemicescoy diet in meditation by autosuggestive cause stomach a feeling of warmth, then a tingling sensation and at the end of the cold feeling. The total duration of meditation - 10-15 minutes It is held 2 times a day for 30-40 days. After a period of remission 1 times a day through the day.

The proposed method allows for successful treatment of hypercholesterolemia in the vast number of patients, regardless of cholesterol level. Concentration is Listerine sharply decreases to normal and if necessary to continue treatment is withheld in this way is at normal levels all the time. This cleared the walls of arteries, veins from the inside, gradually dissolve atherosclerotic plaques. Vessels becomes elastic. In patients with ischemic heart disease angina in the beginning decrease, and then completely stopped. In patients with arterial hypertension normal or significantly reduced blood pressure (table). In patients with vascular lesions of the brain improves the General condition, stop headaches, dizziness, reduced memory. The majority of patients, reduce the dosage and the number of antianginal, antihypertensive agents, or completely stop taking them. In addition improves the function of the gastrointestinal tract. Many patients are cured gastritis, duodenitis, enteritis, colitis, gastric ulcer and 12 duodenal ulcer, intestinal dysbiosis, chronic cholecystitis, cholangitis, pancreatitis, peritoneal commissures and reduced body weight in obese persons. A 10-day course of patients with obesity to reduce body mass on 4-15 kg For the application of this method does not require virtually any, medicines, special conditions, it is available and can be used with high efficiency from an early enough age for the prevention and treatment of the above pathology throughout life is I.

The method is as follows. The diet should be rational and to help patients to shake the mechanism of self-regulation and self-healing organism. For the first 10-15 days, you must go on a salt-free diet. The organism must be unloaded to the maximum, to create the most unusual diet. Meat, fish, dairy products, bread, sugar, coffee, tea, onions, garlic and alcoholic beverages are excluded entirely. Allowed to eat fresh fruits, fresh vegetables or boiled in their skins, honey, nuts and grains. To conduct meditation sessions required the following sequence: warm up - General part and a special part. The workout begins with an arbitrary adaptive physical exercises for warming up the entire body and includes self-massage of biologically active points of a head, ears, and breathing exercises. General session - achieving a state of meditation, autosuggestion called high emotional state, convincing faith in their own abilities to actively overcome the disease. The patient needs to learn actively encourage yourself in the stomach and intestines consistently sensations of heat, cold and tingling. Every sensation is training for about 1 min consecutively 3 times. Breath when this is set to the rhythm of the breath - 6, exhale - 12 C. Special part of the session - meditation state (eyes closed) autosuggestive called feeling the heat transfer in the gut spiral for 5-8 min and the dispersion is then called a sense of movement tingling and cold for 3-5 min and dispersion tingling and coldness in the gut. Tingling can be combined with heat and cold. Moving sensations is best to start with the right iliac region and produce 3-5 circles only in a clockwise direction, narrowing the range of motion to the umbilicus, then 3-5 circles (also clockwise), extending the range of motion to the original circle. Not stopping the movement, sensations of heat to smoothly switch to a tingling sensation, and likewise go with him the whole cycle (3-5 circles to the center and 3-5 circles back). After that, similarly to work with feeling cold.

Example 1. Patient T., 55 years. Diagnosis: Ischemic heart disease. Angina II functional class. Hypertension stage II. Obesity stage I. Hypercholesterolemia. Blood pressure (BP) - 160-170/100-105 mm Hg, cholesterol (LDL) and 7.6 mmol/L. was Enap N 1 PL., Atenolol 25 mg. Aspirin 125 mg per day. Rational diet for 4 weeks. Autosuggestive 2 times a day for 4 weeks for 10-15 min then 1 every 3-5 days a week for 3 months angina disappeared completely, stopped short of breath when walking, improved sleep, appetite, normalized blood pressure and cholesterol (BP 130/80 mm Hg, XC - 4.7 mmol/l). The patient lost 5 kg Reduced the number and dosage of medications: Enap N 1/2 table.. Aspirin 125 mg per day. Improved quality of life.

Example 2. Patient C., 59 years old. Diagnosis: Ischemic heart disease. Angina II functional class. Diffuse non-toxic goiter (autres). AD - 110-120/70-80 mm Hg, XC - 8.5 mmol/L. Took Kardiket 20 mg 2 times a day, OSMO-adalat 1 table. a day Preductal 1 tab. 3 times a day, Aspirin 125 mg per day. Rational diet for 1 month. Autosuggestion in the beginning 2 times a day for 30 days, then 3-5 times a week during the year. After 3 weeks stopped the strokes and not in the course of the year. The patient has stopped taking drugs. Cholesterol decreased gradually to normal in the course of the year and 7.6 mmol/l 6.5 mmol/l to 5.5 mmol/l, 4.7 mmol/L.

Example 3. Patient A., 63. Diagnosis: Ischemic heart disease. Angina functional class I. Atherosclerosis and myocardial infarction (myocardial infarction in 1989). Atherosclerosis coronary artery surgery coronary artery bypass surgery in 1990. Supraventricular and ventricular premature beats. Hernia hiatal. Var is cosna veins of the lower extremities. AD - 140/80 mm Hg, XC - 6.5 mmol/L. Took Lokren 2.5 mg per day, Aspirin 125 mg per day, moduretic 1 table. in 3 days. Rational diet for 30 days. Autosuggestive 2 times a day for 2 weeks, then 3-5 times a week for 2 months. Completely stopped angina, reduced the number of extrasystoles, improved General condition, sleep and appetite. Blood pressure and cholesterol normalized (BP - 120/80 mm Hg, XC - 4.8 mmol/l). The patient currently takes Lokren 2.5 mg 2-3 times a week, Aspirin 125 mg per day. Improved quality of life.

Example 4. Patient L., 74 years. Diagnosis: Ischemic heart disease. Angina II-III functional class. Atherosclerosis and myocardial infarction (myocardial infarction in 1991, 1995). Residual effect of acute disorders of cerebral circulation since 1988 Hypertension III senior Cyst of the left kidney. Diabetes mellitus type II. Extirpate uterus with appendages in 1979 Osteochondrosis of the lumbosacral spine. AD - 170/90 mm Hg, XC - 6.4 mmol/l, blood sugar - 11.0 mmol/L. Took Maninil in table 2. 2 times a day, Sustak Forte 1 tab. 3 times a day, Aspirin 125 mg per day, Korinfar 1 tab. 3 times a day. Rational diet for 4 weeks. Autosuggestive 2 times a day for 4 weeks, then 3-5 times a week for 35 days. Gone is restapi angina, shortness of breath, dry mouth, improved General condition, normalized sleep, appetite. Improved quality of life. AD - 135/85 mm Hg, XC - 4.9 mmol/l, blood sugar - 5.7 mmol/l body Weight decreased by 5 kg

As seen from the above examples, the proposed method is effective in the treatment of hypercholesterolemia as in individuals with borderline cholesterol level (examples 3, 4), and in persons with high cholesterol levels (examples 1, 2).

Table.

Changes in the concentration of blood cholesterol and blood pressure in patients with cardiovascular diseases as a result of treatment by the proposed method.
Nosological formsThe number of patientsBefore the treatment3 months after starting treatment
XC

(mmol/l)
HELL (mm RT. Art.)Cholesterol (mmol/l)HELL

(mm RT. Art.)
Just IBS23measuring 6.5 9.1110-200/60-110of 3.9 to 4.9110-140/60-90
Including:     
CH FC I-III8the 6.5 to 8.1110-130/60-854,1-5,2 110-120/60-80
CH FC I-III96,6-8,5160-190/90-1104,0-5,3130-140/80-90
CH FC I-III36,8-8,9160-200/90-1104,3-5,1130-140/70-90
post-infarction atherosclerosis, cardiosclerosis, GB III St SN FC I-III36,7-9,1165-195/85-110the 4.9 to 5.3130-140/75-90
post-infarction atherosclerosis, cardiosclerosis, GB III V. MTA     
Only GB11of 6.3-9.0160-190/90-110the 3.7 to 5.3130-140/70-90
Including:     
GB II article9of 6.3 to 7.9160-180/90-1003,7-5,0130-140/70-90
GB II, article,

MTA
26,8-9,0180-190/95-1104,5-5,3130-140/80-90
Note: LDL - cholesterol, BP - blood pressure, CHD - coronary heart disease, CH - angina, hypertension hypertension, SPM - vascular lesion of cord, FC - functional the grade, St - stage.

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1. A method of treating hypercholesterolemia in patients with cardiovascular diseases on the responses of lipid-lowering diet, characterized in that advanced state of meditation autosuggestive exposure to evoke the feeling of the heat transfer in the gut in a spiral, starting from the right iliac region and producing 3-5 circles only in a clockwise direction, narrowing the range of motion to the umbilicus, then 3-5 circles clockwise, extending the range of motion to the original circle, also consistently work with sensations of tingling and cold.

2. The method according to claim 1, characterized in that the autosuggestive impact carried out 2 times a day for 30-40 days, and then 1 time a day every other day to maintain cholesterol at a normal level.



 

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