Method for predicting human functional cerebral asymmetry pattern

FIELD: medicine.

SUBSTANCE: method involves determining prognostic parameter values like those of lung ventilation function after spoken rational and irrational test texts. Three values are calculated from the obtained data using linear classification functions. They are compared and functional cerebral asymmetry pattern is to be predicted from their values.

EFFECT: high accuracy and reliability of prognosis.

 

The invention relates to the field of physiology, namely, psychophysiology, and is intended for the objectification of the individual profile of functional asymmetry of the human brain.

Under the profile of functional brain asymmetry understand the totality of the many symptoms of a functional inequality of arms, legs, and right and left halves of the face and body in the formation of General motor activity, as well as neravnoznachnost perception of objects located on the right and left of the Central plane of the body. Functional asymmetry is one of the internal determinants of the mental activity of man, reflecting the process of bilateral regulation and functional specialization of the cerebral hemispheres of man. There are left, right and ravnokonechny profiles of functional asymmetry of the brain.

There is a method of determining the profile of functional asymmetry of the human brain with the use of tests to determine the leading of the right (left) eye, ear, leading right (left) hands, legs or their sensory and motor symmetry with the subsequent calculation of the coefficient of functional asymmetry by the formula (Bay and Tagaropoulou).

The main disadvantages of this method are the subjective assessment of various parameters in the absence of a clear lens is s criteria. This fact is the reason for the low accuracy of the forecast profile of functional asymmetry.

The aim of the invention is to increase the objectivity and accuracy of forecasting profile of functional asymmetry of the person.

This goal is achieved by the fact that determine the values of the prognostic parameters of lung ventilation function after pronunciation rational and irrational text tests, use the values to calculate the three integral indicators Y1, Y2, and Y3 on linear classification functions, compare them with each other and their magnitudes predict the profile of functional asymmetry of the brain.

The method of the invention is implemented in a specific sequence of actions for the two stages. At the first stage receives the necessary quantitative information about the target object, at the second stage, carry out the calculations according to the data from the test trials (linear classification functions) modules integrated indicators characterizing the state of the brain as a single functional system.

For each profile, the functional asymmetry of the brain has its own distinctive unit integral indicator. The degree of functional asymmetry of the brain is directly dependent on this value.

The forecast profile functionality is Noah asymmetry of the human brain is based on the values of the parameters of lung ventilation function, registered, for example, on the device "Eton" (Russia) after speaking examinees text tests (rational and irrational), most significantly reflecting the studied phenomenon (test texts in Appendix 1). Parameters of lung ventilation function registered by the subjects immediately after the read-aloud texts, first - rational, then - irrational (average duration 1 minute). Between stages pronunciation of both texts is the pause for 5 minutes to eliminate trace “layering” of the previous research on the subsequent.

For men such parameters registered after pronunciation rational text are: maximum volumetric rate at the time of expiration of the first 25% of FVC in liters/sec (V1); maximum volumetric rate at the time of expiration of the first 50% of FVC in l/s (V3); average flow velocity at the moment of exhalation between 75% and 85% of FVC in liters/sec (V5); the total time for expiratory FVC (V7); the time required to achieve maximum flow rate of exhalation (V9); maximum the volumetric rate at the moment of first breath 50% of FVC in liters/sec (V12); tidal volume in liters (V14) and after pronunciation irrational text: maximum volumetric rate at the time of expiration of the first 25% of FVC in litres/second (V2); average flow speed in oment exhalation between 25 and 75% of FVC in liters/sec (V4); average flow velocity at the moment of exhalation between 75 and 85% of FVC in l/s (V6); the total time for expiratory FVC (V8); the time required to achieve maximum flow rate of exhalation (V10); peak volumetric inspiratory flow in l/s (V11); maximum volumetric rate at the moment of first breath 50% of FVC in liters/sec (V13); tidal volume in liters (V15).

For women such parameters registered after pronunciation rational text are: maximum volumetric rate at the time of expiration of the first 25% of FVC in litres/second (V2); maximum volumetric rate at the time of expiration of the first 75% of FVC in liters/sec (V4); average flow velocity at the moment of exhalation between 25 and 75% of FVC in l/s (V6); average flow velocity at the moment of exhalation between 75 and 85% of FVC in liters/sec (V8); the time required to achieve peak volume exhalation rate in (V10); peak volumetric inspiratory flow in l/s (V12) and after pronunciation irrational text: maximum volumetric expiratory flow rate in l/s (V1); maximum volumetric rate at the time of expiration of the first 25% of FVC in l/s (V3); maximum volumetric rate at the time of expiration of the first 75% of FVC in liters/sec (V5); average flow velocity at the moment of exhalation between 25 and 75% of FVC in liters/sec (V7); average flow velocity in the moment of exhalation between 75 and 85% of FVC in liters/sec 0/9); the time required to achieve maximum volumetric soon the minute exhalation (V11); the maximum volumetric inspiratory flow in l/s (V13); the maximum volumetric rate at the moment of first breath 50% of FVC in liters/sec (V14); tidal volume in liters (V15).

On the obtained three indicators are calculated integral indicator Y1, Y2 and Y3 linear classification functions:

for men

Y1=is 540+26,03·V1+28,55·V2-42,42·V3-5,80·V4=59,67·V5=22,31·V6=193,06·

V7+135,26·V8-90,41·V9+472,97·V10++309,72·V11+11,90·V12-301,61·V13-

68,20·V14+154,26·V15;

Y2=-581,46+31,97·V1+24,36·V2-52,74·V3-1,83·V4+65,76·V5+21,03·V6+209,95·V7+132,08·V8-

50,78·V9+476,38·V10+301,50·V11+16,07·V12-294,31·V13-68,90·V·14+154,30·V15-

-10,2·V16+11,8·V17-5,9·V18;

Y3=-637,99+18,31·V1+35,57·V2-32,52·V3

are 11.62·V4+62,88·V5+24,14·V6+177,01·V7+180,05·V8-

111,65·V9+446,66·V10++344,65·V11+3,52·V11+3,52·V12-329,26·V13-79,34·V14+167,43·V15.

for women

Y1=-30,10+3,97·V1+14,75·V2-2,71·V3+to 12.44·V4-5,86·V5-

17,65·V6+2,77·V7+0,58·V8+0,64·V9+103,52·V10+3,02V11-388·V12+of 6.31·V13-2,56·V14-7,07·V15;

Y2=-50,63+20,93·V1+24,68·V2-20,63·V3+25,56·V4-11,65·V5-

38,79·V6+17,13·V7-6,29·V8-1,58·V9+256,63·V10-35,17·V11-

13,59·V12-30,82·V13+43,67·V14-12,56·V15;

Y3=-39,45+to 19.74·V1+20,56·V2-19,32·V3+20,96·V4-18,61·V5-

51,53·V6+15,61·V7-1,08·V8+1,32·V9+173,60·V10-26,44·V11-

5,65V·12+10,77·V13-5,79V·14-11,26·V15.

When assessing each participant carried out the comparison of the obtained values Y1, Y2 and Y3. For example, if the largest is the value of Y1, then the test is attributed to the left hemisphere, if the largest is the value of Y2 to the right, if Y3 - to ravnokonechnogo profile of functional asymmetry of the brain.

Example 1. Subject-23 years. Conducted the registration parameters of lung ventilation function on the device "Eton" (Russia) after the speech text tests (rational and irrational) to determine the mathematical model of the profile of functional brain asymmetry. Calculations were set values of integral parameters: Y1=446,84: Y2=423,63; Y3=439,69. The maximum value was integral indicator Y1, which corresponds to the left profile of functional asymmetry of the brain.

Example 2. Tested R-VA, 24 years. Conducted the registration parameters of lung ventilation function on the device "Eton" (Russia) after the speech text tests (rational and irrational) to determine the mathematical model of the profile of functional brain asymmetry. Calculations were set values of integral parameters: Y1=35,07; Y2=29,29; Y3=48,19. The maximum value was integral indicator Y3, which corresponded ravnokonechnogo profile functional asymmetry and brain.

The proposed method allows to objectively predict the profile of functional asymmetry of the brain and can be recommended for use in practical psychophysiology.

Appendix 1

Text 1

Macro - and microcosm or two specific areas of objective reality, different levels of structural organization of matter. The scope of macrolane is the ordinary world in which he lives and acts of people (planet, earthly bodies, crystals, and so on). Qualitatively different area represents the microcosm (atoms, nuclei, elementary particles and other), where the object size is less than the billions of shares centimeters, and the time intervals of the order of billionths of a second, i.e. not directly accessible to observation. Each of these worlds is characterized by the peculiarity of the structure of matter, temporal, spatial and causal relations, patterns of movement. So, in the macrocosm material objects have an explicit discontinuous, particulate, or continuous wave, nature and their movement is subject to dynamic law of classical mechanics. For the phenomena of the microcosm, on the contrary, characterized by a close connection of corpuscular and wave properties, which is reflected in the statistical laws of quantum mechanics.

Text 2

The ineluctable modality of the visible. At least this, if not more, speak my thoughts, my g is Aza. I'm here to read the signs of the essence of things: all of these algae, fry, incoming tide, that won rusty boot. Green, bluesilver, rust, coloured signs. The limits of transparency. But he adds - in bodies. It means that body, he learned before that color. How? And knocking his head on them as of yet. Caution. He bald he was and a millionaire, the master of those who know. The limit of the transparent century. Why? Transparent, opaque. If you can put your five fingers through it, it is a gate, if not a door. Close your eyes and see. Open your eyes. No. Lord! If I fall from the terrible cliff overhanging the sea, will fall irrevocably. Excellent move in the dark. On the side ashen sword. Tap with it - they do. My feet in his boots and his legs, one after another. The sound of solid - forged hammer demiurge Loos. Not in eternity if I go along Sandymount? Directions-crackle, squeak-squeak. The wild sea money. Now open your eyes. Open. Wait. And suddenly everything disappeared during this time? All I will reveal and will be forever in black opaque. Noisemakers! Able to see, will see. Well, look. Was in place and without you; and I will abide.

Sources of information

1. Bragin N.N., Dobrokhotova T.A. Functional asymmetry of human rights. - M.: Medicine. - 1988.

2. Lavrov O.V., Pyatin SCI Guide for practical training in psychophysiology. - Samara., IAF “WITH WHOM”. - 1999.

The method for determining the profile of functional asymmetry of the brain that includes the calculations according to the test research, characterized in that the determined values of lung ventilation function after pronunciation of rational and irrational texts when speaking of rational text for men define:

- maximum volumetric rate at the time of expiration of the first 25% of FVC in l/s (VI)

- maximum volumetric rate at the time of expiration of the first 50% of FVC in l/s (V3),

- average flow velocity at the moment of exhalation between 75% and 85% of FVC in liters/sec (V5),

- total time to expiratory FVC (V7),

the time required to achieve maximum flow rate of exhalation (V9),

- maximum volumetric rate at the moment of first breath 50% of FVC in liters/sec (V12),

- tidal volume in liters (V14);

for women:

- maximum volumetric rate at the time of expiration of the first 25% of FVC in litres/second (V2)

- maximum volumetric rate at the time of expiration of the first 75% of FVC in liters/sec (V4)

- average flow velocity at the moment of exhalation between 25% and 75% of FVC in l/s (V6),

- average flow velocity at the moment of exhalation between 75% and 85% of FVC in liters/sec (V8),

the time required to reach peak volume is karasti exhalation (V10),

- peak volumetric inspiratory flow in l/s (V12);

after speaking of irrational text determine for men:

- maximum volumetric rate at the time of expiration of the first 25% of FVC in litres/second (V2)

- average flow velocity at the moment of exhalation between 25% and 75% of FVC in liters/sec (V4)

- average flow velocity at the moment of exhalation between 75% and 85% of FVC in l/s (V6),

- total time to expiratory FVC (V8),

the time required to achieve maximum flow rate of exhalation (V10),

- peak volumetric inspiratory flow in l/s (V11),

- maximum volumetric rate at the moment of first breath 50% of FVC in liters/sec (V13),

- tidal volume in liters (V15);

for women:

- peak volumetric expiratory flow rate in l/s (V1)

- maximum volumetric rate at the time of expiration of the first 25% of FVC in l/s (V3),

- maximum volumetric rate at the time of expiration of the first 75% of FVC in liters/sec (V5),

- average flow velocity at the moment of exhalation between 25% and 75% of FVC in liters/sec (V7),

- average flow velocity at the moment of exhalation between 75% and 85% of FVC in liters/sec (V9),

the time required to achieve maximum flow rate of exhalation (V11),

- peak volumetric inspiratory flow in l/s (V13),

- maximum volumetric rate at the time of breaths per what's 50% of FVC in liters/sec (V14),

- tidal volume in liters (V15);

on the obtained three indicators are calculated integral indicator Y1, Y2 and Y3 linear classification functions for men:

Y1=is 540+26,03·V1+28,55·V2-42,42·V3-5,80·V4=59,67·V5=

=22,31·V6=193,06·V7+135,26·V8-90,41·V9+472,97·V10+

+309,72·V11+11,90·V12-301,61·V13-68,20·V14+154,26·V15;

Y2=-581,46+31,97·V1+24,36·V2-52,74·V3=1,83·V4+65,76·V5+

+21,03·V6+209,95·V7+132,08·V8-50,78·V9+476,38·V10+

+301,50·V11+16,07·V12-294,31·V13-68,90·V14+154,30·V15-

-10,2·V16+11,8·V17-5,9·V18;

Y3=-637,99+18,31·V1+35,57·V2-32,52·V3-are 11.62·V4+62,88·V5

+24,14·V6+177,01·V7+180,05·V8-111,65·V9+446,66·V10+

+344,65·V11+3,52·V11+3,52·V12-

-329,26·V13-79,34·V14+167,43·V15.

for women:

Y1=-30,10+3,9·V1+14,75·V2-2,71·3+to 12.44·V4-5,86·V5-

17,65·V6+2,77·V7+0,58·V8+0,64·9+103,52·V10+3,02·V11

-388·V12+of 6.31·V13-2,56·V14-7,07·V15;

Y2=-50,63+20,93·V1+24,68·V2-20,63·V3+25,56=V4-11,65·V5-

-38,79·V6+17,13·V7-6,29·V8,58·V9+256,63·V10-35,17·V11-

-13,59·V12-30,82·V13+43,67·V14-12,56·V15;

Y3=-39,45+to 19.74·V1+20,56·V2-19,32·V3+20,96·V4-18,61·V5-

-51,53·V6+15,61·V7-1,08·V8+1,32·V9+173,60·V10-26,44·V11-

-5,65V·12+10,77·V13-5,79V·14-11,26· V15

and, at the greatest value Y1 define the left hemisphere, while the highest value Y2 - right hemisphere and the highest Y3 - ravnokonechny profile of functional asymmetry of the brain.



 

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