Method for rehabilitation in pregnant women with iodine deficiency from ecologically dangerous regions

FIELD: medicine, obstetrics, gynecology.

SUBSTANCE: rehabilitation should be carried out in the third trimester of pregnancy based upon dispensary situated in ecologically safe region, as an enterosorbent one should apply "Carbopect" preparation per 0.5-0.6 g once daily for 3 wk; as an iodine preparation it is necessary to prescribe "Potassium iodide" 200 mcg once daily till the end of pregnancy period and during the whole period of lactation; as adaptogens one should additionally prescribe "Revit" per 2 lozenges thrice daily for 2 wk; vitamin-containing tea; one should, also, apply aerotherapy named "mountain air" per 15-40 min, 15 procedures, totally. The present innovation enables to improve anthropometric parameters in neonatals, decrease the percentage of complications in babies in early neonatal period, among them those that require antibioticotherapy.

EFFECT: higher efficiency of rehabilitation.

2 ex

 

The invention relates to medicine, namely to obstetrics and gynecology, and can be used for the rehabilitation of women who carry a pregnancy in conditions of iodine deficiency and ecological trouble.

There is a method of rehabilitation of pregnant women with iodine deficiency from ecologically disadvantaged areas in the following scheme: step-UPS in the conditions of the perinatal center in terms 8-10 weeks, 20-24 weeks, 30 weeks, 34 and 36 weeks. In addition to traditional research, the survey was conducted on fetal infections, evaluation of immunological status, identification of chemical carriage in biological media. Under this scheme were treated enterosorbent (Carballino) - 3 course for 10-14 days in 8-10 weeks, 20 to 24 and 34 weeks of pregnancy, adaptogens, vitamins 2 courses in 8-10 weeks 20-24 weeks and was carried out prevention of iodine deficiency.

Literature: monograph Features pregnancy, infant health in the conditions of a large industrial city”, MPL, Ipokia, Washeleski. Moscow-Perm, 1999, S. 104.

Disadvantages: this method is not effective enough; long-term (8 to 36 week).

The invention is directed to solving objectives: increase the efficiency of the method rehabilitation pregnant from ecologically unfavorable and iodine-deficient areas.

The specified weight is and is achieved through the rehabilitation course of 24 days on the basis of dispensary, situated in ecologically clean area, starting from the second trimester of pregnancy and destination enterosorbent: “Carbopack” 0.5-0.6 g per day, every day; as iodine-containing drug, “potassium iodide” 200 micrograms a day, every day, until the end of pregnancy and throughout lactation; as adaptogens: “Revit” 2 tablets 3 times a day for 2 weeks, balm “birch”, drug, “Petalon, vitamin tea, holding aerotherapy, “Mountain air” for 15-40 min, a rate of 15 procedures.

The use of these drugs in combination with aerotherapy in the second trimester of pregnancy allows you to achieve optimal results for the rehabilitation of women who carry a pregnancy in terms of ecological and iodine deficiency, and the unborn child.

The method is as follows: a pregnant woman living in conditions of environmental suprisee and iodine deficiency, starting from the second trimester of gestation (from 13 to 26 weeks.) is undergoing rehabilitation at the sanatorium-dispensary, located in the ecologically clean area on the Bank of Kama river.

Destination:

Carbopack 1 chain. (0.5-0.6 g) spoon 1 time/day, daily course of 3 weeks.

Potassium iodide in 200 mg of 1 times/sut., every day, until the end of pregnancy and throughout lactation.

Aerotherapy, “mountain air is, the apparatus Elbrus, exposure 15-40 min, a rate of 15 procedures.

“Revit” 2 other 3 R/day. Course 2 weeks.

Balm “birch” to 1 tablespoon 3 times a day., daily course of 3 weeks.

“Petalon” 30 drops per 50 ml of water 30 minutes before meals 2 times a day for 3 weeks.

Vitamin tea, which includes rose hips, the fruit of the mountain ash, mint, cranberry leaf, 150 ml, 2 times/day., daily course of 3 weeks. Additionally assign:

Diet therapy - with the introduction of iodine-containing foods and iodized mineral water.

Kinesitherapy - exercises for women in the second trimester of pregnancy, including the complex of morning gymnastics, mode gentle, gentle-training, daily course of 24 days.

After a course of rehabilitation as a result of the studies in pregnant normalized rates of thyroid metabolism, decreased the proportion of premature births has increased the number of children with saline during the early neonatal period and decreased time woman and child in the family. branch.

Examples of specific performance

Example 1. Natalia M 22 years old, born in glycine. This second pregnancy, first - year ago ended medical abortion without complications.

In 15 weeks. pregnancy was sent to a sanatorium-preventorium “Spring”, located is in the green zone on the shore R. “Kama”.

Upon admission to the sanatorium looked obstetrician-gynecologist, physician, dentist. On palpation and ULTRASOUND studies have revealed enlargement of the thyroid gland of the first degree. The level of iodine excretion in the urine corresponded to 2.3 µg% (iodine deficiency severe). The IgE levels in the serum 4 times higher than normal.

The pregnant woman was in a sanatorium for 24 days, during which it was received:

Carbopack 1 chain. (0.5 g) spoon 1 time/day, daily course of 3 weeks.

Potassium iodide in 200 mg of 1 times/sut., every day, until the end of pregnancy and throughout lactation.

Aerotherapy, “mountain air”, the “Elbrus”, exposure 15-40 min rate of 15 procedures.

“Revit” 2 other 3 R/day. course 2 weeks.

Balm “birch” to 1 tablespoon 3 times a day., daily course of 3 weeks.

“Petalon” 30 drops per 50 ml of water 30 minutes before meals 2 times a day for 3 weeks.

Vitamin tea, which includes rose hips, the fruit of the mountain ash, mint, cranberry leaf, 150 ml, 2 times/day., daily course of 3 weeks.

Diet therapy - with the introduction of iodine-containing foods and iodized mineral water.

Therapeutic physical exercise - in a sparing mode, walking.

Ultrasound and palpation studies of the thyroid gland, the excretion of iodine in urine was repeated before discharge. The show is tel ioduria was 16,35 ug% (which showed normal provide the body with iodine), on ultrasound volume of the thyroid gland was 17 ml.

According to our recommendations pregnant before delivery continued prevention of iodine deficiency status drug “Potassium iodide” in the dosage of 200 mcg per day.

The woman was examined in glycine in teams of physicians on the basis of the antenatal clinic. Ultrasound and palpation of the thyroid gland and the urinary excretion of iodine with urine showed an adequate diet with iodine: level ioduria was to 24.7 µg%, thyroid volume was 16 ml.

Extract from the birth history: birth in the period of 39 weeks. pregnancy boy weighing 3457 g, length 50 cm, head circumference 34 cm, chest circumference 33 cm, score on a scale of Apgar at 5 min - 9 points. The duration of the first stage of labor was 9 hours and 15 minutes of the second period to 10 minutes, the third - 8 minutes was performed timely amniotomy, estimated blood loss in childbirth was 250 ml. Early neonatal period proceeded without complicated, the mother and the child was discharged home on the 5th day.

Example 2. Elena L. 22 years, born in halexandria. This first pregnancy. At the dispensary maternity consists of 6 weeks. In 16 weeks. pregnancy is directed to a sanatorium-preventorium “Spring”. On palpation and ultrasound of the thyroid size corresponded to normal. The level of iodine excretion in the urine was 4.6 ág% (iodine deficiency average CTE is Yeni gravity). In the serum were reduced performance-Rattc, E-Rollfr, the IgE level 2 times higher than normal. Rehabilitation course included:

Carbopack 1 chain.(0.5 g) spoon 1 time/day, daily course of 3 weeks.

Potassium iodide in 200 mg of 1 times/sut., every day, until the end of pregnancy and throughout lactation.

Aerotherapy, “mountain air”, the “Elbrus”, exposure 15-40 min, a rate of 15 procedures.

“Revit” 2 other 3 R/day. course 2 weeks.

Balm “birch” to 1 tablespoon 3 times a day., daily course of 3 weeks.

“Petalon” 30 cal. 50 ml of water 30 minutes before meals 2 times a day for 3 weeks.

Vitamin tea, which includes rose hips, the fruit of the mountain ash, mint, cranberry leaf, 150 ml, 2 times/day., daily course of 3 weeks.

Diet therapy - with the introduction of iodine-containing foods and iodized mineral water.

Therapeutic physical exercise - in a sparing mode, walking.

Ultrasound and palpation studies of the thyroid gland, the excretion of iodine in urine was repeated before discharge. Indicator iourii were µg of 12.76% (which showed normal provide the body with iodine), ultrasound volume of the thyroid gland was of 16.5 ml.

According to our recommendations pregnant before delivery continued prevention of iodine deficiency status drug “Potassium iodide” in the dosage of 200 mcg per day.

The woman was examined by the in halexandria-based antenatal clinic. Ultrasound and palpation of the thyroid gland and the urinary excretion of iodine with urine showed an adequate diet with iodine: level ioduria was of 18.2 ág%, the volume of the thyroid gland was 17 ml.

Extract from the birth history: birth in term of 40 weeks. pregnant girl weighing 3357 g, length 51 cm, head circumference 33 cm, chest circumference 32 cm, score on a scale of Apgar at 5 min - 9 points. The duration of the first stage of labor was 10 h 18 min, second period - 10 minutes, the third is 5 minutes was performed timely amniotomy, estimated blood loss in childbirth was 180 ml. Early neonatal period proceeded without complicated, the mother and the child was discharged home on the 5th day.

The positive effect of using the proposed method medico-ecological rehabilitation, received the improve the quality of service of obstetrics and childhood Perm region: increased proportion of normal physiological childbirth, improved anthropometric indicators of children decreased the percentage of complications in children in the early neonatal period, including requiring treatment with antibiotics, and the percentage of children requiring second phase of nursing in the hospital.

The method of rehabilitation of pregnant women with iodine deficiency from ecologically disadvantaged areas by assigning chelators, drugs iodine and adaptogens, including balsam birch and drug Fitolon”, and diet therapy, physical therapy and symptomatic treatment, physical therapy, characterized in that the rehabilitation is conducted in the second trimester of pregnancy on the basis of dispensary, located in an ecologically clean area, as enterosorbent drug use “Carbopack” 0.5-0.6 g of 1 times a day, every day, the course of 3 weeks; as preparation of iodine designate “potassium iodide” 200 mg of 1 times a day, every day, until the end of pregnancy and throughout lactation; as adaptogens appoint “Revit” 2 tablets 3 times a day, the course 2 weeks; vitamin tea, which includes rosehips, Rowan, mint and cranberry leaf; as physiotherapy use aerotherapy: procedure “mountain air” for 15-40 min, the rate of 15 procedures.



 

Same patents:

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention describes compound of the formula (I):

as a free form or salt wherein Ar means group of the formula (II):

wherein R1 means hydrogen atom or hydroxy-group; R2 and R3 each means independently of one another hydrogen atom or (C1-C4)-alkyl; R4, R5, R6 and R7 each means independently of one another hydrogen atom, (C1-C4)-alkoxy-group, (C1-C4)-alkyl or (C1-C4)-alkyl substituted with (C1-C4)-alkoxy-group; or R5 and R6 in common with carbon atoms to which they are joined mean 6-membered cycloaliphatic ring or 6-membered heterocyclic ring comprising two oxygen atoms; R8 means -NHR13 wherein R13 means hydrogen atom, (C1-C4)-alkyl or -COR14 wherein R14 means hydrogen atom; or R13 means -SO2R17 wherein R17 means (C1-C4)-alkyl; R9 means hydrogen atom; or R8 means -NHR18 wherein -NHR18 and R9 in common with carbon atoms to which they are joined mean 6-membered heterocycle; R10 means -OH; X means (C1-C4)-alkyl; Y means carbon atom; n = 1 or 2; p = 1; q = 1; r = 0 or 1. Also, invention describes pharmaceutical composition based on compound of the formula (I), a method for preparing compound of the formula (I) and intermediate compound that is used in the method for preparing. Compounds elicit the positive stimulating effect of β2-adrenoceptor.

EFFECT: improved preparing method, valuable medicinal properties of compounds.

13 cl, 3 tbl, 35 ex

The invention relates to new imidazole compounds of the formula I:

where R1represents hydrogen, hydroxy, protected hydroxy, or aryl, optionally substituted with a suitable(and) substituent(s) selected from the group consisting of halogen(lower)alkyl, halogen, hydroxy, protected carboxy, carbamoyl, lower alkylenedioxy, lower alkoxy, optionally substituted aryl, and lower alkyl, optionally substituted by hydroxy or protected carboxy; R2represents hydrogen or lower alkyl; R3is hydroxy or protected hydroxy; R4represents cyano, (hydroxy)minamino(lower)alkyl, carboxy, protected carboxy, N-containing heterocyclic group, optionally substituted amino, or carbarnoyl, optionally substituted with a suitable(s) of the substituent(s) selected from the group consisting of amino, hydroxy, lower alkyl, lower alkylsulfonyl, amidoamine(lower)alkyl, optionally substituted by hydroxy; and-And - is-Q -, or-O-Q-, where Q is a single bond or lower alkylene, or its salt, provided when R2is the lowest Ala the substituent(s), the above, and also provided that the compound of formula I is not 1-(hydroxyethyl)-4-(etoxycarbonyl)imidazole or anilide 1-(2-hydroxyethyl)imidazole-4-carboxylic acid

The invention relates to medicine, in particular to cancer, and can be used in radiation therapy of malignant tumors of the pelvic organs

The invention relates to medicine and concerns of Pediatrics and treatment of infectious diseases, namely infectious mononucleosis in children

The invention relates to the objects of the invention characterized in the claims, i.e

The invention relates to medicine, endocrinology, anesthesiology and critical care medicine and can be used as infusion therapy when ketoacidotic coma in patients with diabetes mellitus
The invention relates to medicine, operative gynecology, anesthesiology and can be used for anesthesia in cosmetic surgery for vulva in women

The invention relates to an extract of Tanacetum parthenium, practically does not containunsaturated-lactones

The invention relates to medicine, obstetrics, and can be used to increase nonspecific resistance of the pregnant woman to the generic act

The invention relates to medicine, pharmacology, and can be used for the treatment in mammals of infertility, disorders of spermatogenesis failure of the reproductive function, as well as to enhance the ability to fertilize

FIELD: medicine, cosmetology.

SUBSTANCE: one should restore and strengthen lipid epidermal barrier, activate metabolic processes in skin cells and protect skin against damaging factors by applying sea buckthorn lipids, moreover, before restoring and strengthening lipid epidermal barrier one should additionally purify the skin deeply against contamination and sebum; moreover, the above-mentioned stages of restoration and strengthening lipid epidermal barrier, activation of metabolic processes in skin cells and its protection against damaging factors should be carried out successively, moreover, activation of metabolic processes in skin cells should be performed by applying a preparation containing sea buckthorn and cedar lipids at their ratio being 0.5 - 1.5, correspondingly. Moreover, deep skin purification against contamination and sebum should be conducted by applying a preparation containing cedar lipids. Moreover, restoration and strengthening of lipid epidermal barrier should be performed with a preparation containing sea buckthorn lipids, and skin protection against damaging factors - with a preparation containing cedar lipids.

EFFECT: higher efficiency of skin aging prevention.

3 cl, 3 ex

FIELD: food industry.

SUBSTANCE: invention relates to biologically active additives containing carbohydrate syrups and provides biologically active additive based on plant Comarum palustre L. Additive is prepared in the from of in the form of syrup and contains aqueous extract of Comarum palustre L. Extract is obtained by infusion of broken raw material for 20 h at 80-90оС and raw material-to-water ratio 1:10. Additive further includes citric acid, sorbic acid, and sugar at specified proportions. Additive can be used as preventive health-improving agent in cases of elevated loadings on locomotor system as well as in cases of such diseases osteochondrosis, gout, rheumatism, polyarthritis.

EFFECT: enhanced preventive and healing effect.

3 cl

FIELD: medicine, phytotherapy, pharmacy.

SUBSTANCE: invention relates to preparations of vegetable origin. Invention proposes the preparation eliciting immunomodulating effect and comprising aqueous-alcoholic extracts of the following plants, mas. p. p.: glabrous licorice roots, 5.0-15.0; fenestrate Saint-John's-wort herb 4.0-16.0; dandelion roots, 4.0-16.0; sandy immortelle flowers, 3.5-14.0; senna leaves, 3.5-14.0; thyme herb, 1.0-4.0; snowdon rose (rosewort) rhizomes and roots, 0.05-0.2. Also, invention proposes the preparation comprising condensed or an aqueous-alcoholic extract of above said plants and a filling agent. The preparation can be made as tablet or capsule. The preparation normalizes the blood free radicals content and provides elevating level of T-suppressors with the simultaneous reducing amount of T-helpers in blood of patients in treatment of acute and chronic inflammatory diseases of breathing organs.

EFFECT: valuable medicinal properties of preparation.

2 cl, 3 tbl, 1 ex

FIELD: medicine, virology, pharmaceutical industry, pharmacy.

SUBSTANCE: invention proposes the preparation used for treatment of viral hepatitis C that comprises birch bark extract with the content of betulin above 70% and a pharmaceutically acceptable carrier. The preparation is administrated to patient by oral route. The preparation promotes to the effective treatment of viral hepatitis C. Invention can be used in treatment of viral hepatitis C.

EFFECT: valuable medicinal properties of agent.

4 cl, 2 tbl

FIELD: medicine, pharmaceutical industry.

SUBSTANCE: invention relates to agents used for treatment of chronic hepatitis. The hepatoprotective agent representing extract prepared from biomass of Maackia amurensis Rupr. et Maxim and obtained by the callus culture method comprises polyphenolic complex consisting of daidzein, retusin, genistein, formononetin, maackianin and medicarpin. The hepatoprotective agent promotes to effective treatment of chronic hepatitis.

EFFECT: valuable medicinal properties of agent.

2 tbl

FIELD: medicine.

SUBSTANCE: method involves using air-dried vegetable raw. Hollow horse-mint (Monarda) raw treated by steam is extracted with vegetable oil in the ratio raw : extract = 1:10 at heating for 5 h on water bath at temperature 60-70oC followed by filtration. Method provides the possibility for year-round manufacturing the hollow horse-mint (Monarda) oily extract eliciting with the high antibacterial and expressed anti-fungal activity.

EFFECT: improved preparing method.

1 tbl, 1 ex

FIELD: pharmaceutical industry and technology, pharmacy.

SUBSTANCE: invention relates to a method for preparing extract based on walnuts at milkwax stage of ripeness. Method for preparing extract based on walnuts involves grinding walnuts at milkwax stage of ripeness taken with pericarps, drying to air-dry state, mixing with wild rose fruits ground and dried to air-dry state and taken in the definite ratio of components followed by treatment with aviation kerosene and stirring at room temperature. Method provides preparing extract with the higher content of biologically valuable substances and to increase the assortment of vegetable supplements.

EFFECT: improved preparing method.

2 tbl

FIELD: organic chemistry, natural compounds, medicine, oncology.

SUBSTANCE: invention represents new saponin mixtures used for inhibition of initiation and activation of mammalian epithelial cell in pre-malignant or malignant state, for stimulation of apoptosis of mammalian malignant cell, prophylaxis of anomalous proliferation of mammalian epithelial cell, for treatment of inflammatory and regulation of angiogenesis in mammal. These mixtures are isolated form plants of species Acacia victoriae. Also, invention relates to methods for their applying. These compounds can comprise triterpene component, such as acacic or oleanolic acid to which oligosaccharides and monoterpenoid components are joined. Mixtures and compounds elicit properties associated with regulation of apoptosis and cytotoxicity of cells and strong anti-tumor effect with respect to different tumor cells.

EFFECT: valuable medicinal properties of compositions.

43 cl, 53 tbl, 50 dwg, 44 ex

FIELD: beauty products manufacturing.

SUBSTANCE: the present innovation deals with manufacturing cosmetic composition that contains solubilized cumic alcohol of a certain formula, glucose, ascorbic acid or compound which is split in skin up to glucose or ascorbic acid and a cosmetically acceptable carrier. Components should be taken at a certain quantitative ratio. The suggested composition improves expression of transglutaminase-1 and ceramides in skin cells and enhances absorption of glucose and ascorbic acid by cells.

EFFECT: higher efficiency.

1 cl, 5 ex, 12 tbl

FIELD: organic chemistry, chemical technology, agriculture.

SUBSTANCE: invention relates to a method for preparing the preparation comprising triterpenic acid water-soluble salts and additionally added protein-containing product and vegetable raw, the source of triterpenic acids taken in the following ratio of components, wt.-%: protein-containing product, 10-17; triterpenic acid sodium salts, 4-5, and vegetable raw, the balance. Method involves mixing triterpenic acid-containing vegetable raw with the protein-containing product taken in the ratio = (9-11):(1-2), mechanical-chemical treatment of this mixture in activator device, mixing of prepared semi-finished product with sodium carbonate or sodium hydrocarbonate taken in the ratio = (92-97):(3.5-8.3) and repeated treatment in the activator device. Method involves applying flow-type ball vibration-centrifugal or ellipse-centrifugal mills as the activator device that provide the acceleration of milling bodies up to 170-250 m/c2 and time for treatment for 1.5-3 min. Invention provides simplifying the process and the complex processing waste in lumber industry.

EFFECT: improved preparing method.

6 cl, 1 tbl, 6 ex

The invention relates to medicine, namely to neurology, and can be used for the treatment of dyscirculatory encephalopathy
Up!