Device for continuous monitoring of the heart activity

 

The invention relates to the field of medical equipment, namely to design devices for the transfer of electrocardiogram radio, and can be used in practical health care, including in the system of the ambulance, in the system of distance counselling centres. An object of the invention is the increased robustness and selectivity panoramic receiver device. The device includes electrodes, pre-amplifier, a microprocessor, memory blocks of the lower and upper levels, the first block of comparison, adjustable threshold unit, the processing unit alarm, magnetic recorder, the unit audible alarm generator high frequency, the amplitude modulator, the baseband generator code phase manipulator, power amplifier, transmitting antenna, receiving antenna, the power adjustment, the first and second local oscillators, first and second mixers, first and second intermediate frequency amplifiers, a detector, first and second delay lines, the first and second keys, the amplitude limiter, a synchronous detector, a phase detector, a doubler phase, the first and second measures the width of the spectrum, the first and second threshold block is worn to the field of medical technology, namely, to design devices for the transfer of electrocardiogram radio, and can be used in practical health care, including in the system of the ambulance, in the system of distance counselling centres.

Known devices for continuous monitoring heart activity and for diagnosing diseases of the heart (ed. mon. The USSR№№776604, 1301376, 1311706, 1364298, 1377030, 1389751, 1409221, 1421303, 1535529, 1540800, 1641272, 1671264, 1725828, 1797856, 1811380, 1814538; patents of the Russian Federation№№2012225, 2012226, 2026636, 2028077, 2077864, 2080820, 2166798, 2108061, 2128004, 2181258; U.S. patents№№3616790, 4022192, 4231374, 5002064: the heart monitor. Apparatus for continuous ECG monitoring. Edited Baranovskogo A. L. et al. - M Radio and communication, 1993 and others).

Known devices closest to the proposed is a Device for continuous monitoring of the heart activity (patent RF №2181258, And 61 In 5/04, 2000), which is selected as a prototype.

The specified device contains electrodes, pre-amplifier, the microprocessor, the first and second blocks of the comparison, the memory blocks of the lower and upper levels, first adjustable threshold unit, the processing unit alarm, magnetic recorder, the unit audible alarm, a high-frequency generator, amplitudinous antenna, unit realignment, local oscillator, mixer, intermediate frequency amplifier, a detector, first and second delay lines, key, amplitude limiter, a synchronous detector, phase detector, the first and second measures the width of the spectrum, the doubler phase and the second threshold unit. The known device can increase the reliability of remote monitoring heart activity of the observed person.

However, in a panoramic receiver of the known device is the same value intermediate frequency W can be obtained by receiving signals on two frequencies W1and W, i.e. W=W1-W and Wnp=W-W.

Therefore, if the frequency W1to take over the main channel, along with it will be a mirror of the receive channel frequency W which differs from the frequency of W1on 2W and is symmetrical (mirrored) relative to the frequency W lo. Conversion on the image receiving channel is the same conversion factor of the CRC, as the main channel. Therefore, it is most significantly affect the selectivity and robustness panoramic receiver that is part of the known device.

But a mirror there and drumette when the condition is met:

W=/±mWi±nW/,

where wi - frequency Raman receiving channel;

m, n positive integers.

The most harmful combination receiving channels are channels formed by the interaction of the carrier frequency signal with harmonics of the lo frequency of small order (second, third, and so on), because the sensitivity of the panoramic receiver through these channels close to the sensitivity of the main channel.

So, two Raman channel for n=2 and m=1 correspond to the frequencies (Fig.3):

W to1=2W-Wp, W to2=2W+Wp.

The presence of false signals (interference), taken in the mirror and Raman channels, leads to decreased immunity and selectivity panoramic receiver.

An object of the invention is the increased robustness and selectivity panoramic receiver device.

The problem is solved in that the device for continuous monitoring of the heart activity, containing series-connected electrodes, pre-amplifier, an amplitude modulator, a second input connected to the output of the high-frequency generator, a phase manipulator, a second input connected to the output of the generator modulating code, Roy entrance through which the first local oscillator coupled to the output block adjustment, the control input of which is connected to the output of the second threshold unit, and the first intermediate frequency amplifier, cascaded detector, the second input is through the first delay line is connected with its output, the first key, the amplitude limiter, a synchronous detector, a second input connected to the output of the first key, the microprocessor and the shaping unit alarm first and second outputs of which are connected respectively to the unit and audible alarm magnetic recorder, the output of the amplitude limiter connected in series, the second delay line and a phase detector, a second input connected to the output of the amplitude limiter, and the output is connected to the second input magnetic recorder, a third input connected to the output of a synchronous detector, the microprocessor is made in the form of the first unit of comparison, the memory blocks of the lower and upper levels and an adjustable first threshold unit whose output is the output of the microprocessor, the input of which is the input of the first unit of comparison, which are connected respectively to the memory blocks of the lower and upper levels and to the first threshold unit comes with a second heterodera key and to the output of the block adjustment sequentially connected to the second local oscillator, a second mixer, a second input connected to the output of the receiving antenna, the second intermediate frequency amplifier, a correlator, a second input connected to the output of the first intermediate frequency amplifier, the third threshold unit and the second key, a second input connected to the output of the first intermediate frequency amplifier, and the output connected to the first input detector and the first key, the first frequency W1and second W2local oscillators separated by twice the value of the intermediate frequency

W2-W1-2Wp,

selected symmetric with respect to the frequency W1the main receive channel

W1-W1=W2-W1=Wp

and rebuilt synchronously.

Structural diagram of the device shown in Fig.1. Block diagram of the detector shown in Fig.2. Frequency chart explaining the process of formation of additional receiving channels is shown in Fig.3 timing diagrams explaining the principle of operation of the device shown in Fig.4.

The device comprises a series-connected electrodes 1, a preamplifier 2, amplitude modulating the od which is connected to the output of the generator 13 modulating code, the amplifier 15 power and transmitting antenna 16, consistently included receiving antenna 17, the first mixer 20, the second input is via the first local oscillator 19 is connected to the output of block 18 of perestroika, the control input of which is connected to the output of the detector 22, and the first amplifier 21 intermediate frequency, connected in series to the output of block 18 of perestroika, the second local oscillator 34, the second mixer 35, a second input connected to the output of the receiving antenna 17, the second amplifier 36 intermediate frequency, the correlator 37, a second input connected to the output of the first amplifier 21 intermediate frequency, the third threshold unit 38, the second key 39, a second input connected to the output of the first amplifier 21 intermediate frequency, detector 22, the second input is through the first delay line 23 is connected with its output, the first key 24, a second input connected to the output of the second key 39, the amplitude limiter 25, synchronous detector 26, a second input connected to the output of the first key 24, the microprocessor 3 and the block 8 of the formation of an alarm signal, the first and second outputs of which are connected to the magnetic recorder 9 and block 10 audible alarm, sequentially connected to the output amplanning limiter 25, and the output is connected to the second input magnetic Registrar 9, a third input connected to the output of the synchronous detector 26.

Thus, the microprocessor 3 is made in the form of the first block 5 comparison of memory blocks of the bottom 4 and top 6 levels, and an adjustable first threshold unit 7, the output of which is the output of the microprocessor 3, the entrance of which is the input of the first block of 5 comparisons, which are connected respectively to the memory blocks of the bottom 4 and top 6 levels and to the first threshold unit 7.

The detector 22 is made in the form of cascaded doubler 30 phase meter 31 spectrum width of the second harmonic, the second unit 32 of the comparison, a second input connected to the output of the meter 29 spectrum width, and the second threshold unit 33, a control input connected to the output of the first delay line 23, and the output is the output of the detector, the input of the doubler 30 phase meter 29 spectrum width of the signal are combined and the input of the detector 22.

As block 18 adjustment is used, as a rule, the sawtooth generator.

Device for continuous monitoring of the heart activity is as follows.

The electrodes 1 krepyatsya disorders and diseases, etc) in places of removing ECG, from which depends largely on the quality of the shooting electrocardiogram. While there is interference due to physiological reasons (artifacts), and interference associated with methodological impediments.

Interference caused by physiological reasons, depend on the potentials of skeletal muscles and are generally considered to be the main factor hindering the registration of the currents of the heart during active muscle activity. To reduce these interference electrodes 1 must be connected in biopolar chest leads. This is because the chest the amplitude of the ECG is the most important, and the pectoral muscles are not actively participating in the movement process. Among the two pole chest leads is advisable to use lead Sky in which three electrodes are as follows.

The first electrode is located right at the point of insertion of the third rib to the breastbone. The second level of the fifth rib on the left srednerusskoi line. The third electrode is at the level of the fourth rib in the mid-axillary line on the left.

The system leads the Sky includes lead:

And between the first and second electrodes,

D - between the first and third electrodes,

I - between the second and tentially side and rear walls of the heart.

Interference of the second group associated with methodical moments, basically more substantial and control plays a major role. These include interference of two kinds:

a) noise from the bias electrodes when the jolts and shocks that inevitably arise in dynamic conditions;

b) electrical noise and distortion, with sometimes quite complicated.

The displacement of the electrodes causes interference due to the fact that it is accompanied by short change of contact resistance between the electrodes and the skin.

Interference of an electrical nature are diverse, and almost all expressed the greater, the more the resistance value of the transitional contact between the electrodes and the skin.

To combat methodological noise and distortion should:

a) to stabilize the value of contact resistance;

b) to do this magnitude is not only constant, but possibly less.

The first is achieved either by the use of Cup electrodes, filled pasta and attached to the skin by leolam and additionally ribbons of adhesive tape, or the use of liquid electrodes - suckers. The latter provide greater reliability due to the fact that the attachment is an absolute homogeneous contact medium, the property which has not significantly changed by the intense sweating investigated.

The second is the reduction of contact resistance is achieved by a complex process Vodolazskiy P. A. because of the high electrical resistance of the skin is due to the properties as of the stratum corneum of the epidermis, and fat grease. Processing involves two steps - careful removing the top layer of the epidermis by wiping abrasive paste (soap cream with it pumice in the ratio 4:1) and subsequent cleaning and degreasing the skin with a mixture Nikiforova (alcohol and ether in the ratio 1:1).

Recorded by electrodes 1 cardioseal m(t) (Fig.4, a), passing through the pre-amplifier 2, is fed to the first input of the amplitude modulator 12, the second input of which is applied a high-frequency oscillation output from the generator 11 high frequency (Fig.4, b)

U1(t)=V1·Cos (W1·t+1), 0tT1.

where V1, W1,1T1- amplitude, carrier frequency, initial phase, and the duration of harmonic oscillations.

The output amplitude of the Cos (W1·t+1), 0tT1,

where V2=1/2K1·V1;

K1- the ratio of the amplitude modulator;

m(t) - law amplitude modulation;

AM signal U2(t) arrives at the first input of the phase manipulator 14, to the second input of which is applied a modulating code M(t) (Fig.4, g), which in digital form contains brief information about the monitored person, such as name, year of birth, and other bibliographic information. The output of the phase manipulator 14 is formed a complex signal with a combined amplitude modulation and phase shift keying (AM-FMN) (Fig.4, d).

U3(t)=V3·[1+m(t)]· Cos (W1·t+to(t)+1), 0tT1.

where V3=1/2K2·V2;

To2- the ratio of the amplitude modulator;

K(t)={0,} - manipulated component phases, reflecting the law of phase manipulation in accordance with modulate)e and may change abruptly at t=touh, i.e., at the boundaries between elementary parcels (K=0, 1, 2,... N-1);

uh, N - the length and number of basic assumptions which form the signal duration T1(T1=Ne).

This signal, after amplification in the amplifier 15 of the power radiated by the transmitting antenna 16 in the air, the admission antenna 17 and is supplied to the first inputs of the mixers 20 and 35, the second inputs of which are served voltage oscillators 19 and 34, respectively:

IG1(t)=VG1·Cos(W1·t+· t2+g1), 0tTA.

IG2(t)=VG2·Cos(W2·t+· t2+g2),

where VG1, VG2, W1, W2g1,g2, TP - amplitude, initial frequency, initial phase, and the repetition period of the voltages of the oscillators of the Df.

At this frequency the first W1and lo 19 and the second W2lo 35 spaced at twice the value of the intermediate frequency 2 Wp

W2-W1=2Wp,

selected symmetric with respect to the frequency W1main channel

W1-W1=W2-W1=Wp

and rebuilt synchronously.

The outputs of the mixers 20 and 35 are formed of the voltage Raman frequencies. Amplifiers 21 and 36 intermediate frequency allocated voltage differential (intermediate) frequency:

Ypres1(t)=V4·[1+m(t)]· Cos[Wp· t+K(t)-·· t2+PR1],

Ypres2(t)=V5·[1+m(t)]· Cos[Wp· t+K(t)+·· t2+PR2], 0tT1,

where V4=1/2K3·V4·VG1;

V5=1/2K3·V3·VG2;

K3- gain mixers;

Wp=W1-W1=W2-W-g1;PR2=g2-1.

These stresses are complex signals with a combination of amplitude modulation, phase shift keying and linear frequency modulation (AM-FMN-chirp). With linear frequency modulation force occurs due to the adjustment of the frequencies of the local oscillators in a linear fashion.

Voltage Ypres1(t) and Ypres2(t) are fed to the two inputs of the correlator 37, the output of which produces a voltage V(), is proportional to the correlation function R(), which is compared to a threshold unit 38 with a threshold level Uop2. The threshold level Uop2exceeded only at the maximum value of the correlation function Rmax() (Vmax()). Since the channel voltage Ypres1(t) and Ypres2(t) are formed by one and the same complex signal received on two channels at the same frequency W1between the specified channel voltages there is a strong correlation. The correlation function R(Voltage Ypres1(t) from the output of the amplifier 21 intermediate frequency via a public key 39 to the input of the detector 22, consisting of the first 29 and second 31 measures the width of the spectrum of the doubler phase 30, block 32 comparison and threshold unit 33.

At the output of the doubler phase 30 is formed voltage

U4(t)=V6·[1+m(t)]· Cos[2Wp· t-2·· t2+2PR1], 0tT1,

in which phase shift keying already present.

The spectral widthf2the second harmonic signal is determined by the duration of T1signal

f2=1/T1,

while the spectral widthFC of the received signal is determined by the durationuh its basic packages

FC/f2=N.

Therefore, by multiplying the phase of the AM-FMN-chirp signal on two of its range “collapsed” N times. This circumstance allows to detect the input complex signal even when its input power panoramic receiver is less than the noise power and interference.

The spectral widthfc of the input signal is measured using a meter 29 and the width of the spectrumf2the second harmonic signal is measured using a meter 31. Voltage Vc and V2proportional toFC andf2accordingly, outputs of the probes 29 and 31 of the spectrum width is fed to two input block 32 comparison. As Vc>>V2the output of block 32 comparison produces a positive pulse which is compared with the threshold voltage Uop1in the threshold block 33. The threshold voltage Uop1exceeded only upon detection of AM-QPSK signal. If the threshold level Uop1in the threshold block 33 is formed by a constant voltage, hunt control input key 24, opening it.

From this point in time view of the specified frequency range Df and search for AM-QPSK signals terminated at the time of registration of the detected S-QPSK signal, which is determined by the delay time1delay line 23.

At the termination of the restructuring of the local oscillator 19 to the input of the amplifier 21 of the intermediate frequency voltage is formed

Ypres3(t)=V4·[1+m(t)· Cos[Wp· t+K(t)+PR1], 0tTi,

which through the public keys 39 and 24 is fed to the input of the amplitude limiter 25 and the synchronous detector 26. The output of the amplitude limiter 25 is formed QPSK signal (Fig.4,e)

U6=V0·Cos[Wp· t+K(t)+PR1], 0tT1,

where V0the threshold limit,

which is supplied to the second input of the synchronous detector 26 and to the inputs of delay lines 27 and phase detector 28. In the synchronous detection on the output of a synchronous detector 26 is formed of a low-frequency e.g. the ratio of transmission of the synchronous detector;

proportional to the source cardiomegaly m(t) (Fig.4, a). This voltage is fed to the input of block 5 comparison of the microprocessor 3, which compares the recorded signal of a specific patient with established for the normal person, the lower and upper limits input to the block 5 comparison with blocks 4 and 6 of the memory of the lower and upper levels. When the deviation of the recorded signal for the maximum permissible torque is triggered adjustable threshold unit 7, including the block 10 an audible indication and a magnetic recorder 9. Last writes for 5-10 seconds and registration of pathological process on the portable cartridge.

The device is powered by a portable power source (not shown). The delay line 27 and a phase detector 28 provides detection of QPSK signal U6(t) (Fig.4, e) by the method of relative phase manipulation, which is free from the phenomenon of “reverse”. When this delay time2the delay line 27 is equal durationE. elementary parcels (2=e) (Fig.4 is oselka. The output of the delay line 27 is formed voltage (Fig.4, C)

U7(t)=V0·Cos[Wp· (t-2)+K(t-2)+PR1], 0tT1,

which comes to the second input of phase detector 28. The output of the last formed of the low-frequency voltage (Fig.4,)

UH2(t)=VH2·CosK(t)

where VH2=1/2K5V20;

K6- gain of the phase detector;

proportional to the modulating code M(t) (Fig.4, g). This voltage is fixed magnetic Registrar 9.

Thus, the magnetic recorder 9 provides registration information about the patient and his pathological data on the cardiovascular system.

Latency1delay line 23 is selected such that it was possible to record information about the patient and his pathological data on the cardiovascular system on the magnetic tape. After this time, the voltage output from the delay line 23 is fed to the input Speroni mode adjustment, and the keys 39 and 24 are closed, i.e. they must be in their original condition. From this point in time view of the specified frequency range Df u search AM-QPSK signals continues.

In case of detection of the next S-QPSK-signal operation of the device is similar.

The device may be made in versions designed for patients with various cardiovascular disorders (arrhythmia, ischemic heart disease), enter the reference information to the microprocessor, which will be the comparison of the recorded signals. For example, a patient with a predisposition to proximale tachycardia will be monitored cardiac cycles, if extrasystole - periodicity, the number and shape of extrasystoles, myocardial ischemia, a programming device is configured to compare the amplitude, direction and duration of waves and intervals of the ECG.

The device provides remote obtain objective information about the condition of the heart in real conditions of social and industrial life, provides personalized remote monitoring of heart activity in a specific patient, promptly notifies you of appearance is whitesky and rehabilitation measures. This remote control is carried out simultaneously with the heart activity of several patients, which use radio signals of different frequencies and modulation codes, which transmit radio except kardiosignalas still and patient information.

The device can be used in preventive cardiology research, practical work with the appropriate contingent, in sports medicine, aerospace flight for diagnosis and prevention of disorders and abnormalities of cardiac activity among truck drivers.

The above operation corresponds to the case of receiving useful S-QPSK signals in the main channel at the frequency W1(Fig.3).

If a false signal (interferer) is received at the first mirror frequency W1(Fig.3), the mixers 20 and 35, it is converted to voltage following frequencies:

W11=W1-W1+1t=Wp+1t;

W12=W2-W1+1t=3Wp+1t;

W(2)11=2W1-W1+2t;

W(2)

the second index denotes the number of the local oscillator, the frequency of which is involved in the conversion of the carrier frequency of the received false signal (interference);

index to the extent denotes a second harmonic of the lo frequency;

1,2- the rate of change of the first and second harmonics of the frequencies of the local oscillators (2=21).

However, only the voltage with a frequency W11fall in bandwidthW amplifier 21 intermediate frequency. The output voltage of the correlator 37 is zero, since the bandwidthW amplifier 36 intermediate frequency voltage is missing. The key 39 is opened and a false signal (interferer) taken on the first mirror frequency W1suppressed.

For a similar reason is suppressed and a false signal (interferer), adopted at the second mirror frequency W2at first W to1the second W to2, W to third3and the fourth W to4Raman frequencies.

If the interfering signals (noise) are taken of the following frequencies:

W11=W1+W1t-W1=Wp+1t;

W12=W2-W1t-3Wp+1t;

W(2)11=2W1+2t-W1;

W(2)12=2W2+2t-W1;

W21=W2-W1-1t=3Wp1t;

W22=W2-W1-1t=Wp1t;

W(2)21=2W1+2t-W2;

W(2)22=2W2+2t-W2;

In this case, the voltage and frequency W11and W22fall respectively in bandwidthW amplifiers 21 and 36 intermediate frequency. However, the key 39 is opened. It declares the fact that different interfering signals (noise) are taken at different frequencies W1and W2so between the channel voltages there is a weak correlation. The output voltage of the correlator 37 does not exceed the threshold level Vop2<1and second W2mirror frequencies are suppressed.

In addition, it should be noted that the correlation function of noise does not have a clearly defined main lobe, as is the case in complex signals.

For a similar reason suppressed and false signals (interference), taken at the same time on the first W to1and the second W to2Raman frequencies, or two or more other Raman or other frequencies.

Thus, the proposed device is compared with the prototype and other technical solutions for a similar purpose provides increased robustness and selectivity panoramic receiver device. This processing channel stress and remarkable property of the correlation function of complex signals. When this frequency W1and W2local oscillators separated by twice the value of the intermediate frequency

W2-W1=2Wp,

selected symmetric with respect to the frequency W1the main receive channel

W1-W1=W2-W1=Wp

and rebuilt synchronously. This circumstance leads to a doubling of the number of additional receiving channels, but creates favorable conditions for their suppression of the correlation Elnett heart containing series-connected electrodes, pre-amplifier, an amplitude modulator, a second input connected to the output of the high-frequency generator, a phase manipulator, a second input connected to the output of the generator modulating code, the power amplifier and transmitting antenna series the receiving antenna, the first mixer, the second input is via the first local oscillator coupled to the output block adjustment, the control input of which is connected to the output of the first threshold unit, which is the output of the detector, and the first intermediate frequency amplifier, cascaded detector, a second input which are combined inputs of measuring the width of the signal spectrum and doubler phase, to which are connected in series meter width of the spectrum of the second harmonic and the second block of comparison, a second input connected to the meter output spectrum width of the signal, and the first threshold unit, the control input of which is through the first delay line coupled to the output of the detector, the first key, the amplitude limiter, a synchronous detector, a second input connected to the output of the first key, the microprocessor and the forming unit C is magnetic to the Registrar, the output of the amplitude limiter connected in series, the second delay line and a phase detector, a second input connected to the output of the amplitude limiter, and the output connected to the second input magnetic recorder, a third input connected to the output of a synchronous detector, the microprocessor is made in the form of the first unit of comparison, the memory blocks of the lower and upper levels and adjustable threshold block whose output is the output of the microprocessor, the input of which is the input of the first unit of comparison, which are connected respectively to the memory blocks of the lower and upper levels and to the first threshold unit, characterized in that it is provided with a second local oscillator, the second mixer, the second intermediate frequency amplifier, a correlator, a second threshold unit and the second key, and to the output of the block adjustment sequentially connected to the second local oscillator, a second mixer, a second input connected to the output of the receiving antenna, the second intermediate frequency amplifier, a correlator, a second input connected to the output of the first amplifier intermediate frequency, the second threshold unit and the second key, a second input connected to the output Progetti first Wr1and the second Wr2local oscillators separated by twice the value of the intermediate frequency

Wr2-Wr1=2W,

selected symmetric with respect to the frequency W1the main receive channel

W1-Wr1=Wr2-W1=W,

synchronous with their rebuilding.



 

Same patents:

The invention relates to the field of medical equipment, namely to design devices for the transfer of electrocardiogram radio, and can be used in practical health care, including in the system of the ambulance, in the system of distance counselling centres

The invention relates to medicine, namely to identify informative parameters of ST-segment electrocardiograma, namely the displacement, slope, shape, deviation of the peak ST-segment from its center, and combinations of these parameters, and can be used to analyze changes in ST-segment electrocardiogram (EX) to detect abnormalities in the early stages of heart disease

The invention relates to medicine, namely to identify informative parameters of ST-segment electrocardiograma, namely the displacement, slope, shape, deviation of the peak ST-segment from its center, and combinations of these parameters, and can be used to analyze changes in ST-segment electrocardiogram (EX) to detect abnormalities in the early stages of heart disease
The invention relates to medicine, namely to orthopedics

The invention relates to medicine, namely to pediatric cardiology

The invention relates to medicine, particularly cardiology

The invention relates to medicine, obstetrics

The invention relates to medicine, obstetrics

The invention relates to medicine, in particular to electronic devices for reflexology, and can be used to identify and influence on biologically active points

The invention relates to medicine, and is intended for examination (screening) of the population in order to identify the pathology of internal organs at the early stages of the disease and can be used for examination in the hospital, outpatient clinic, at home and in the field in the absence of computer

FIELD: medicine.

SUBSTANCE: method involves carrying out pulsating Doppler echocardiographic examination. Mean pressure is determined in pulmonary artery. Mean pressure in pulmonary artery being less than 13 mm of mercury column, no cardiac rhythm disorders risk is considered to take place. The value being greater than 13 mm of mercury column, complex cardiac rhythm disorder occurrence risk is considered to be the case.

EFFECT: accelerated noninvasive method.

1 tbl

FIELD: medicine, neurology, psychopathology, neurosurgery, neurophysiology, experimental neurobiology.

SUBSTANCE: one should simultaneously register electroencephalogram (EEG) to detect the level of constant potential (LCP). At LCP negativization and increased EEG power one should detect depolarizational activation of neurons and enhanced metabolism. At LCP negativization and decreased EEG power - depolarized inhibition of neurons and metabolism suppression. At LCP positivation and increased EEG power - either repolarized or hyperpolarized activation of neurons and enhanced metabolism. At LCP positivation and decreased EEG power - hyperpolarized suppression of neurons and decreased metabolism of nervous tissue. The method enables to correctly detect therapeutic tactics due to simultaneous LCP and EEG registration that enables to differentiate transition from one functional and metabolic state into another.

EFFECT: higher accuracy of diagnostics.

5 dwg, 1 ex, 1 tbl

FIELD: medicine, neurology, psychopathology, neurosurgery, neurophysiology, experimental neurobiology.

SUBSTANCE: one should simultaneously register electroencephalogram (EEG) to detect the level of constant potential (LCP). At LCP negativization and increased EEG power one should detect depolarizational activation of neurons and enhanced metabolism. At LCP negativization and decreased EEG power - depolarized inhibition of neurons and metabolism suppression. At LCP positivation and increased EEG power - either repolarized or hyperpolarized activation of neurons and enhanced metabolism. At LCP positivation and decreased EEG power - hyperpolarized suppression of neurons and decreased metabolism of nervous tissue. The method enables to correctly detect therapeutic tactics due to simultaneous LCP and EEG registration that enables to differentiate transition from one functional and metabolic state into another.

EFFECT: higher accuracy of diagnostics.

5 dwg, 1 ex, 1 tbl

FIELD: veterinary medicine.

SUBSTANCE: method involves interpreting dynamic omega potential behavior pattern relative to its initial level during 6-7 min after applying artificial pain irritation. The method is applied beginning from animal age of 1 month. Omega potential is measured before and after pain irritation test. Omega potential level growing down, the animal is considered to be of low stress stability. Omega potential level growing high, the animal is considered to be of high stress stability.

EFFECT: enhanced effectiveness of method.

2 dwg, 2 tbl

FIELD: medicine, cardiology.

SUBSTANCE: one should register rhythmocardiogram, measure current total power in low-frequency and high-frequency areas of dynamic row of cardiointervals. Evaluation of psychophysiological state should be performed by the value of stress index S calculated due to original mathematical formula by taking into account the power of low-frequency and high-frequency constituents of the range of dynamic row of cardiointervals. In case of standard conditions of measurement - the rest lying at one's back position the value of S stress index should be considered to be equal to 1. The method enables to rapidly and noninvasively detect and range human psychophysiological state.

EFFECT: higher accuracy of evaluation.

2 dwg, 1 ex, 2 tbl

FIELD: medicine, neurology.

SUBSTANCE: one should establish neurological status, bioelectric cerebral activity, availability of perinatal and ORL pathology in patients, establish their gradations and numerical values followed by calculation of prognostic coefficients F1 and F2 by the following formulas: F1=-31,42+1,49·a1-2,44·a2+0,2·а3+1,63·a4+0,62·а5+3,75·a6+1,8·а7-3,23·a8-0,8·а9-1,32·а10+3,26·а11+8,92·a12-2,0·a13+3,88·а14+1,79·a15+0,83·a16-2,78·a17; F2=-27,58+1,43·a1+3,31·а2+0,08·а3+3,05·а4-0,27·а5+2,69·а6+3,11·а7-6,47·a8-6,55·a9+1,99·а10+5,25·а11+7,07·a12-0,47·a13+0,13·a14+4,04·a15-1,0·a16-1,14·а17, correspondingly, where a1 - patient's age, a2 - studying either at the hospital or polyclinic, a3 - duration of stationary treatment (in days), a4 - unconscious period, a5 - terms of hospitalization since the moment of light close craniocerebral trauma, a6 - smoking, a7 - alcohol misuse, a8 - arterial hypertension, a9 - amnesia, a10 - close craniocerebral trauma in anamnesis, a11 - psychoemotional tension, a12 - meteolability, a13 - cervical osteochondrosis, a14 - ORL pathology, a15 - availability of perinatal trauma in anamnesis with pronounced hypertension-hydrocephalic syndrome, a16 - availability of paroxysmal activity, a17 - availability and manifestation value of dysfunction of diencephalic structures. At F1 ≥ F2 on should predict the development of remote aftereffects in young people due to evaluating premorbid background of a patients at the moment of trauma.

EFFECT: higher reliability of prediction.

2 ex, 1 tbl

FIELD: medicine; medical engineering.

SUBSTANCE: method involves doing multi-channel recording of electroencephalogram and carrying out functional tests. Recording and storing rheoencephalograms is carried out additionally with multi-channel recording of electroencephalogram synchronously and in real time mode in carotid and vertebral arteries. Electroencephalograms and rheoencephalograms are visualized in single window with single time axis. Functional brain state is evaluated from synchronous changes of electroencephalograms, rheoencephalograms and electrocardiograms in response to functional test. The device has electrode unit 1 for recording bioelectric brain activity signals, electrode unit 2 for recording electric cardiac activity signals, current and potential electrode unit 3 for recording rheosignals, leads commutator 4, current rheosignal oscillator 5, synchronous rheosignal detector 6, multi-channel bioelectric brain activity signals amplifier 7, electrophysiological signal amplifier 8, demultiplexer 9, multi-channel rheosignal amplifier 10, multi-channel analog-to-digital converter 11, micro-computer 12 having galvanically isolated input/output port and personal computer 13 of standard configuration.

EFFECT: enhanced effectiveness of differential diagnosis-making.

11 cl, 6 dwg

FIELD: medicine, pulmonology.

SUBSTANCE: in patients with chronic bronchitis one should detect the level of central frequency of diaphragmatic spectrum due to myography at attempt of inhalation in case of overlapping respiratory tract at the level of residual volume (CFRVD) in Hz. Simultaneously, one should detect maximal oral inspiratory pressure (Oip)in kPa. Due to mathematical formula including altered parameters it is necessary to calculate criterial D value to diagnose hyperreactivity of respiratory tract.

EFFECT: higher efficiency of diagnostics.

2 ex

FIELD: poultry science.

SUBSTANCE: the present innovation deals with visual evaluation in chicken followed by testing them by the value of bioelectric potential. Chickens with bioelectric potential being significantly higher against average values are considered to be stress-resistant ones and those with bioelectric potential being significantly lower against average values in concrete population are concluded to be stress-sensitive ones. The method is very simple in its implementation and efficient for large-scale selection in poultry on stress-resistance.

EFFECT: higher efficiency.

1 cl, 2 dwg, 2 ex, 4 tbl

FIELD: medicine, functional diagnostics.

SUBSTANCE: one should apply active electrodes in frontal (Fz), occipital (Cz), parietal (Td, Ts) areas, as for reference electrode it should be applied in area of right-hand wrist. Registration of constant potential level (CPL) should be performed under conditions of decreased impact of cutaneous resistance. Then the data obtained should be compared with pre-established normative ones for this age group. One should apply mean values and root-mean-square (rms) deviations, moreover, if CPL value obtained is not beyond the limits of Fz = 15.95 ± 3.88 mV, Cz = 25.71 ± 4.56 mV, Oz = 25.92 ± 5.39 mV, Td = 24.18 ± 5.45 mV, Ts = 22.51 ± 6.06 mV, in this case CPL distribution shows normal cerebral energetic state.

EFFECT: higher accuracy of evaluation.

2 ex

Up!