Plate for osteosynthesis

 

(57) Abstract:

The invention relates to medicine and can be used in oral and maxillofacial surgery, traumatology and orthopedics. Plate for osteosynthesis made of N-vinylpyrrolidone (N-VP) with a thickness of 1-1 .5 mm with the addition of drugs, accelerating regeneration and osseointegration of bone tissue. The invention provides for reduction of terms of treatment of fractures. 1 PL.

The invention relates to medicine and can be used in oral and maxillofacial surgery, traumatology and orthopedics.

It is known to use metal plates for osteosynthesis of fractures of the jaw bone, in particular, made of titanium, which require removal after healing, which leads to the need for additional surgical intervention, increased duration of treatment and disability (Surgery: Textbook / Ed. by T. G. Robotboy. 2nd ed., revised and enlarged extra - M.: Medicine, 1996. S. 402-403).

It is also known the use of plates for osteosynthesis, made of polylactide and polyglycolides, in particular LACTOSORB (Eppley B. L. The Journal of Craniofacial Surgery, vol. 8, No. 2, march, 1997, p.85-86) that undergo resorption, which is Sorbie plate of polylactide and polyglycolides takes from 12 to 24 months. These plates are available only to a thickness of 1.5 and 2.0 mm

LACTOSORB plate, made of a copolymer of polylactic and polyglycolic acids in the ratio of 82:18, selected as a prototype.

The objective of the invention is the reduction of terms of treatment of fractures.

This is due to the fact that the plate is made of N-vinylpyrrolidone (N-VP) with a thickness of 1-1 .5 mm with the addition of drugs, accelerating regeneration and osseointegration of bone tissue.

N-VP - synthesized copolymer of vinylpyrrolidone with methylmethacrylate, reinforced polyamide fiber, previously used for fixation of bone fragments bones of the limbs in the form of intraosseous pins, as well as mass to eliminate bone cavities (defects of the lower jaw and chin). Approved for use by the orders of the Ministry of health No. 1217 from 25.10.84, No. 386 from 20.03.86, No. 1027 from 06.08.86, No. 1025 from 05.08.86, and the Commission decision on General surgery (Protocol No. 6 of 20.12.89 year). During implantation in biological tissues pins and weight are gradual resorption. During use has proved to be the best.

In the experiment on the animals (25 adult rabbits of Parodia (see table).

The appearance in the damage zone of cellular elements, characteristic of a normal hard and soft tissues, is faster at the plate of N-VP and greater N-EAP with orotovoy acid.

In addition, N-EAP in comparison with LACTOSORB has an adjustable period of resorption due to the properties of N-VP, thickness and additives included, accelerating regeneration and osseointegration, which is of great importance to determine the timing of subsequent stages of treatment (orthopedics, rehabilitation). The terms biodegradable and strength depend on the percentage of copolymers and sizes of plates. The plate thickness is taken in the range from 1 to 1.5 mm depending on the severity of the fracture. The plate is fixed to the bone by a standard method.

Plate for osteosynthesis of a polymeric material, characterized in that it is made of N-vinylpyrrolidone (N-VP) with a thickness of 1-1 .5 mm and with the addition of drugs, accelerating regeneration and osseointegration of bone tissue.



 

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