The method of preparation of the canals of the tooth for the filling

 

(57) Abstract:

The claimed method relates to medicine, namely to dentistry, and can be used in the preparation and sterilization of the root canal system to the filling. In channel enter solution of photosensitizer concentration of 56 M and within 5-6 minutes to process the channel beam of the diode laser power of 0.5-1.0 W and a wavelength of 662 nm, first apical zone, then its median part and then repeat steps, completing the sterilization by irradiation of the mouth of the channel. The method allows to increase the efficiency of root canal treatment due to the fact that the solution of the photosensitizer is adjudged to be in small tubules and anastomoses, thus, the whole root system is exposed to sterilization, as well as to influence the apical and capitalnew pathogenic micro channel, which increases the efficiency of endodontic treatment.

The present invention relates to medicine, namely to dentistry, and can be used in the preparation and sterilization of the root canal system for filling.

Many domestic and foreign scholars in recent years have argued that, despite what exactly high. This is due to the fact that ultimately, a cure and save the tooth must accurately perform three stages of treatment: mechanical expansion of the channel, chemotherapeutic treatment of tooth and full three-dimensional obturation of the root canal system. Although the first and third stages are a requirement for all clinical situations, to enforce them is not always easy (Brayton, S. M., Davis, S. R., and Goldman, M.: Gutta-percha root canal fillings. Oral Surg. 35:226, 1973; Cash, P. W: Electronics in endodontics practices - a clinical report on the Endometer, Those. Dent. J. 90:21, 1972; Seltzer, S.; Endodontology; biologic considerations. In Endodontic procedures. New York, 1971, MeGraw-Hill Book Co., pp. 318-325). In addition, the researchers showed that when sterility channel violation of territorial fit does not necessarily leads to inflammation in the periapical region (Phillips, J. M.: Rat connective tissue response to hollow polyethylene tube implants, J. Can. Dent. Assoc. 33:59, 1967; Tomeck, C. D.: Reaction of rat connective tissue to polyethylene tube implants, part I, Oral Surg. 21:379, 1966; Tomeck, C. D.: Reaction of rat connective tissue to pro tube implants, part II, Oral Surg. 24:674, 1967).

Therefore, although the filling of the root canal system plays an important role, careful processing and purification from microorganisms are equally important condition of successful treatment.

Proper cleaning of the root canal system can gain PAE moves anastomoses and so on (Schilder, N., and Yee, F. S.: Canal gebridement and disinfection. In Cohen, S., and Bums, R. C., editors: Pathways of the puip, ed. 3, St. Louis, 1984, The C. V. Vosby Co). Thus, 95% of all operative complications depends on the quality of biochemical treatment.

A thorough biological and mechanical treatment of the root canal hand tools has always been a tedious process that takes a lot of time (Rubin, L., et al.: The effect of instrumentation and flushing of freshly extracted teeth in endodontic therapy: a scanning electron microscope study, J. Endod. 3:194, 1977).

Effective irrigation of the root canal is also difficult, so as to deliver the washing solution to the apical area is extremely difficult. Often a narrow channel does not allow for adequate irrigation, because of what the inside of the channel is a mixture of dentinal sawdust, bacteria and residues of pulp that contributes to the blocking areas of the root canal including lateral canals, preventing its biological treatment.

Known sterilization method canals before preparing the filling (Harrison, J. W., and Hand, R. E.: The effect of dilution and organic matter on the antibacterial property of the 5.25% sodium hypochlonte, J. Endod. 7:128, 1981), which provides for the irrigation of the root canals of a 3% solution of hydrogen peroxide (H2ABOUT2), as this drug the possession is their and shallow channels.

However, hydrogen peroxide does not dissolve tissue and ineffective as a lubricant. To trigger the release of oxygen, increasing, thus, the foaming and the formation of bubbles needed to penetrate and remove the residual organic substances, it was recommended to combine bleach with 3% hydrogen peroxide in the channel. However, this inhibits their individual antibacterial properties.

For the prototype we have adopted the way chemomechanical treatment of the root canal, which includes irrigation channels after their expansion with a mixture of irrigating solutions. Used in complex irrigation solutions: sodium hypochlorite and hydrogen peroxide (Ingle, J. I., and Taintor, J. F.: endodontics practices, ed. 3., Philadelphia, 1985, Lea & Febiger, p. 178). It is recognized that the most important irrigating solution used in endodontics is sodium hypochlorite (NaOCl). The concentration of the applied solution ranges from 0.5 to 5.25%, but usually it is 2.5%. Sodium hypochlorite has the property well to dissolve live, necrotic and fixed tissues. He has a strong bactericidal effect, is an excellent lubricant and bleaching agent, the long-term remains and economically profitable (R is comprised of:

- the necessity of their use in a restricted space of the channel, as the hit of these solutions beyond the channel, especially under pressure, leads to severe toxic effects, tissue damage, and give rise to acute pain and swelling. These concerns motivate physicians to significantly reduce the concentration of the fluids used. However, the decrease in the concentration leads to a significant deterioration in the efficiency of irrigant;

- hydrogen peroxide does not dissolve tissue and ineffective as a lubricant;

- when combining sodium hypochlorite with 3% hydrogen peroxide inhibited their individual antibacterial properties;

- to deliver the washing solution to the apical part of the canal is extremely difficult;

- irrigant not get caught in the fine tubules and anastomoses, thus, the whole root system is not processed.

Objectives: increase the efficiency of processing and sterilization of the root canal system.

The invention consists in that the preparation of the canals before filling is carried out using the introduction in the channel of a solution of photosensitizer concentration of 56 M and within 5-6 minutes process is nnow part and then repeat steps, completing the sterilization by irradiation of the mouth of the channel.

The method is as follows.

After trephination, removing the pulp or residual pulp tissue and mechanical expansion of the root canal it is treated with solutions of EDTA, sodium hypochlorite or hydrogen peroxide, cleaned and dried with a paper pins. Then carry out the sterilization of the root canal using the proposed method.

To do this enter channel 56 M aq photosensitizer for 5-6 minutes, to cause absorption of the photosensitizer in all dentinal tubules. The length of the channel defined radiographically or by using an apex locator, is transferred to the laser handpiece flexible fiber length of 30 mm and a diameter of 0.4 mm (with rubber stopper). The fiber is introduced into the channel, not far from 3 mm to the apex, thereby purposefully energy of the diode laser is directed toward the apical area.

Used a diode laser with a wavelength of 662 nm, emission mode continuous power 0,5-1,0 W.

The next step, the fiber is introduced into the middle part of the channel, not reaching apex of about 7 mm, and the manipulation is repeated again as described above for the sterilization of the Central part of the channel. And in conclusion sensibilization, resulting in a high level singleentry oxygen and free radicals, which destroy the membrane of all microbial cells, thereby sterilizing the entire network of the root canal with its branches.

After sterilization of the root canal it is washed with saline and dried with a paper pins. Directly following this, performing the traditional filling of the root canal.

It should be remembered that the laser beam must be moved only in the direction from the apical position out of the channel. Thereby prevent the jam laser tip in the root canal.

During preparation of the root canal for filling the application of the proposed method was tested in 100 patients aged 26 to 74 years, 50 patients was similar in the control group, the treatment which was carried out in the traditional way.

The majority of patients (74%), previously seeking dental care in other dental offices, was denied in endodontic treatment for a variety of reasons: obstruction of root canals (42%), periodontitis with pronounced changes in the periapical area (32%). Patients who trained the cat) did not complain. 4 patients inconvenience arose only when receiving solid foods in 2-3 days.

When preparing channels for filling our proposed method in all patients after 1 month disappeared fistulous passages and other signs of inflammation, while monitoring the long-term exacerbation of chronic periodontitis was not observed.

When x-ray examination 6 months after preparation of root canals in chronic periodontitis is not revealed destructive processes were observed partial or complete elimination of the source of the degradation due to the regeneration of bone tissue in the periapical lesion. The preparation of root canals has led to a complete sanitizing effect in all cases without exception, that is, under the influence of laser radiation in combination with the photosensitizer was the complete elimination of the microflora of root canals. Refractory to laser sterilization of patients was not. Patients of the main group at the control examination after 1 year after treatment with the application of the proposed method the clinical picture was more favorable. It was not marked discomfort and painful sensations. Radiographically in the periodontal tissues patologicheskogo channel with a laser creates the conditions for optimal preparation of the channel followed by filling. Root canal treatment with laser support reduces the frequency of postoperative complications related to the preparation of the root canal, to zero. Sensitivity at namasivaya after filling the root canal is absent.

54% of patients in the control group, the treatment which was carried out in the traditional way, within 4-5 days felt pain when namasivaya in the field of causal tooth.

The pain was sometimes increased by food intake, particularly solid. And in patients with initial stages of periodontal diseases and longer.

At the control examination after 12 months after filling channels in 5 (10%) patients of the control group showed slabosolenaja percussion.

4 (8%) patients in the control x-rays increased width of the periodontal gap and foci rarefaction of bone tissue in the apical part of the roots.

The effectiveness of laser sterilization of root canals is confirmed by the following clinical examples.

Example 1. Patient D. 36 years old, complains of pain in the area 21 of the tooth increases with namasivaya. Pain appeared about 1 month ago. About 1 year ago was treating this tooth. Objective: the prevalence of the Sabbath.

Bite orthognathic. CPU=5+4+8=17. In a small number there are soft and hard dental deposits (lingual surface of the anterior teeth of the lower jaw). Data number - 2040 m/sec. Data LDF: MD - 19,6 srvc. unit, PS - 24,0 services. unit, Gr - 0,20. Performed control viziografiya 21 of the tooth. Pictured is determined fragmentary presence of filling material in the channel.

The channel is not sealed to the apex of 3.5 mm is Determined by the presence of the chip tool in the Central part of the channel. In the apex 21 - tooth hearth rarefaction of bone tissue rounded shape with sharp edges with a diameter of 7 mm

On the basis of history, clinical examination and additional laboratory methods was diagnosed with granulomatous periodontitis 21 tooth in the acute stage.

Treatment: Antiseptic mouth. Held the opening 21 of the tooth. Conducted opening and Rosprombank channel 21 of the tooth. Using ultrasonic scaler, profiles and Sonik Air removed from the channel filling material and the chip tool. The extension of the channel 21 of the tooth profile to 40 size ISO. Held laser sterilization of the root canal 21. The channel length is determined using the apex locator, purines M solution of photosensitizer for 5 minutes, that happened absorption it all dentinal tubules.

The fiber was introduced into the canal, not far from 3 mm to the apex, thereby the energy of the diode laser was directed to the apical area. The laser power of 0.5 W, continuous mode.

The next step, the fiber was introduced into the middle part of the channel, not reaching apex of about 7 mm, and the manipulation was repeated again as described above for the sterilization of the Central part of the channel. And finally, the fiber was left in the mouth of the channel and processed in the same way.

After sterilization of the root canal it was washed with saline and dried with a paper pins. Directly following this, held a traditional filling of the root canal.

Example 2. Patient K.,48 years old, came with complaints of spontaneous pain in 36 tooth, occurring mostly at night. The pain is aggravated by eating and thermal stimuli. According to patient's spontaneous pain appeared 7 days ago. The tooth was previously cured about tooth decay.

At objective inspection in 36 tooth found the remains of an old filling. Probing the bottom of the cavity 36 of the tooth is sharply painful. Response to cold sharply positive. Percussion labopol arouno.

Bite orthognathic. CPU=2+6+3=11. In a small number are hard dental deposits (lingual surface of the anterior teeth of the lower jaw). Data number - 2548 m/sec. Data LDF: MD - 18,8 srvc. unit, PS - 23,0 srvc. unit, Gr - 0,12. Performed control viziografiya 36 tooth.

In the picture is determined by a carious cavity, soamsawali with pulp chamber, periodontal gap slightly dilated, rarefaction of bone tissue in the periapical tissue was not found.

On the basis of history, clinical examination and additional laboratory methods was diagnosed with chronic pulpitis of the tooth 36.

Treatment: Under infiltration anesthesia Sol. Ultracain D-S forte, 1.7 ml, prepared carious cavity of the tooth 36. The cavity is disclosed. After trephination, removing the pulp and residual pulp tissue and mechanical expansion of the root canal up to 40 ISO, channels, as usual, washed EDTA, sodium hypochlorite, cleaned and dried the cavity of paper pins. Then performed the sterilization of root canals with a laser. For this purpose, in each channel introduced 56 M aq photosensitizer for 5-6 minutes, to cause absorption of the photosensitizer in all dentinal canals the IR flexible fiber length of 30 mm and a diameter of 0.4 mm (with rubber stopper).

The fiber alternately introduced into the channels, not reaching 3 mm to the apex, thereby purposefully energy of the diode laser was directed to the apical area. The laser power was 1 W, continuous mode.

The next step, the fiber was introduced into the middle part, not reaching apex of about 7 mm, and the manipulation was repeated again as described above for the sterilization of the Central part of each of the channels. And finally, the fiber was left in the mouth of the channel and processed in the same way.

After sterilization of root canals they were washed with saline and dried with a paper pins. Directly following this, held a traditional root canal filling. The channels 36 of the tooth sealed material EN 26 using guttapercha pins method of lateral condensation.

The crown part of the tooth was recovered material "SYNERGY" ("Coltene", Swiss quality for Dentistry).

When viewed in 3 days the patient to the pain and discomfort did not complain.

At the control examination after 1 year after treatment, the clinical picture was favorable. It was not marked discomfort and painful sensations. Radiographically in the periodontal tissues, there were no changes obner gangrenous pulpitis in many cases, if time and circumstances, the teeth can be sealed in one visit. But usually after sterilization in the root canal left the medicinal substance, and during the second visit is the filling channel. Thus, it is possible to carry out a successful root canal treatment and save important for prosthetic teeth.

After that, the channel can be sealed without causing further postoperative complaints. Due to the effect of sterilization in the apical region is achieved reduction of bacteria by 99%. Qualitative canal filling completely closes the lumen of the channel and completes the treatment.

Treatment of root canals with a laser effective, easy and quickly creates conditions for optimal preparation of the channels to filling. Sensitivity at namasivaya after obturation of root canals minimal and lasts no more than 2-3 days.

Analyzing the results of the testing method, it can be concluded that the proposed method is easy to use, well tolerated, has no side effects and contraindications for use.

The technical result of this method is:

- utsutsu hit these solutions beyond them, especially under pressure, and does not lead to a strong intoxication, damage to the surrounding tissues and give rise to acute pain and swelling.

- increases the efficiency of root canal treatment due to the fact that the solution of the photosensitizer is adjudged to be in small tubules and anastomoses, thus, the whole root system is exposed to sterilization;

- potential impact on apical and capitalnew pathogenic micro channels, which increases the efficiency of endodontic treatment;

- the ability to achieve good success without the use of antibiotics and all the negative consequences associated with it.

Clinical benefits of applying the proposed method are the ease and speed of application, the sterility of the treated surface.

The method can be recommended to improve the quality of therapeutic treatment of root canals, especially in terms of health insurance.

The method of preparation of tooth for filling, including the expansion of channels, the extirpation of pulp or tissue, characterized in that the channel enter solution of photosensitizer concentration of 56 M and within 5-6 min education the middle part and then the steps again, completing the sterilization by irradiation of the mouth of the channel.



 

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FIELD: medicine.

SUBSTANCE: method involves introducing 0.1-0.3 ml of photosensitizing gel preliminarily activated with laser radiation, after having removed neovascular membrane. The photosensitizing gel is based on a viscoelastic of hyaluronic acid containing khlorin, selected from group containing photolon, radachlorine or photoditazine in the amount of 0.1-2% by mass. The photosensitizing gel is in vitro activated with laser radiation having wavelength of 661-666 nm during 3-10 min with total radiation dose being equal to 100-600 J/cm2. The gel is introduced immediately after being activated. To compress the retina, vitreous cavity is filled with perfluororganic compound or air to be further substituted with silicon oil. The operation is ended with placing sutures on sclerotomy and conjunctiva areas. Compounds like chealon, viscoate or hyatulon are used as viscoelastic based on hyaluronic acid. Perfluormetylcyclohexylperidin, perfluortributylamine or perfluorpolyester or like are used as the perfluororganic compound for filling vitreous cavity.

EFFECT: excluded recurrences of surgically removed neovascular membrane and development of proliferative retinopathy and retina detachment; retained vision function.

3 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: method involves making incision in conjunctiva and Tenon's capsule of 3-4 mm in size in choroid hemangioma projection to sclera 3-4 mm far from limb. Tunnel is built between sclera and Tenon's capsule to extrasclerally introduce flexible polymer magnetolaser implant through the tunnel to the place, the choroid hemangioma is localized, after performing transscleral diaphanoscopic adjustment of choroid hemangioma localization and size, under visual control using guidance beam. The implant has permanent ring-shaped magnet in the center of which a short focus scattering lens of laser radiator is fixed. The lens is connected to light guide in soft flexible envelope. The permanent implant magnet is axially magnetized and produces permanent magnetic field of 2-3 mTesla units intensity. It is arranged with its north pole turned towards the choroid hemangioma so that extrascleral implant laser radiator disposition. The other end of the implant is sutured to sclera 5-6 mm far from the limb with two interrupted sutures through prefabricated openings. The implant is covered with conjunctiva and relaxation sutures are placed over it. Light guide outlet is attached to temple using any known method. 0.1-1% khlorin solution is injected in intravenous bolus dose of 0.8-1.1 mg/kg as photosensitizer and visual control of choroid hemangioma cells fluorescence and fluorescent diagnosis methods are applied. After saturating choroid hemangioma with the photosensitizer to maximum level, transscleral choroid hemangioma laser radiation treatment is carried out via laser light guide and implant lens using divergent laser radiation at wavelength of 661-666 nm with total radiation dose being equal to 30-120 J/cm2. The flexible polymer magnetolaser implant is removed and sutures are placed on conjunctiva. Permanent magnet of the flexible polymer magnetolaser implant is manufactured from samarium-cobalt, samarium-iron-nitrogen or neodymium-iron-boron system material. The photosensitizer is repeatedly intravenously introduced at the same dose in 2-3 days after the first laser radiation treatment. Visual intraocular neoplasm cells fluorescence control is carried out using fluorescent diagnosis techniques. Maximum level of saturation with the photosensitizer being achieved in the intraocular neoplasm, repeated laser irradiation of the choroid hemangioma is carried out with radiation dose of 30-60 J/cm2.

EFFECT: enhanced effectiveness of treatment.

4 cl

FIELD: medicine.

SUBSTANCE: method involves creating tunnel between sclera and Tenon's capsule in intraocular neoplasm projection. Intraocular neoplasm localization and size is adjusted by applying transscleral diaphanoscopic examination method. 0.1-0.3 ml of photosensitizing gel based on viscoelastic of hyaluronic acid, selected from group containing chealon, viscoate or hyatulon, is transsclerally introduced into intraocular neoplasm structure using special purpose needle in dosed manner. The photosensitizing gel contains khlorin, selected from group containing photolon, radachlorine or photoditazine in the amount of 0.1-1% by mass. Flexible polymer magnetolaser implant is extrasclerally introduced into the built tunnel in intraocular neoplasm projection zone under visual control using guidance beam. The implant has permanent ring-shaped magnet axially magnetized and producing permanent magnetic field of 3-4 mTesla units intensity, in the center of which a short focus scattering lens of laser radiator is fixed. The lens is connected to light guide in soft flexible envelope. The implant is arranged with its north pole turned towards the intraocular neoplasm so that implant laser radiator lens is extrasclerally arranged in intraocular neoplasm projection zone. The implant light guide is sutured to sclera 5-6 mm far from the limb with single interrupted suture. The implant is covered with conjunctiva and relaxation sutures are placed over it. Light guide outlet is attached to temple using any known method. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, transscleral intraocular neoplasm laser radiation treatment is carried out via laser light guide and implant lens using divergent laser radiation at wavelength of 661-666 nm. The treatment course being over, the flexible polymer magnetolaser implant is removed and sutures are placed on conjunctiva. Permanent magnet of the flexible polymer magnetolaser implant is manufactured from samarium-cobalt, neodymium-iron-boron or samarium-iron-nitrogen. 0.1-1% khlorin solution as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is additionally intravenously introduced in 2-3 days at a dose of 0.8-1.1 mg/kg and repeated laser irradiation of the intraocular neoplasm is carried out with radiation dose of 30-45 J/cm2 15-20 min later during 30-90 s.

EFFECT: complete destruction of neoplasm; excluded its further growth.

4 cl

FIELD: medicine.

SUBSTANCE: method involves applying transscleral diaphanoscopic examination method for adjusting intraocular neoplasm localization and size. Rectangular scleral pocket is built 2/3 times as large as sclera thickness which base is turned from the limb. Several electrodes manufactured from a metal of platinum group are introduced into intraocular neoplasm structure via the built scleral pocket. Next to it, intraocular neoplasm electrochemical destruction is carried out in changing electrodes polarity with current intensity of 100 mA during 1-10 min, and the electrodes are removed. Superficial scleral flap is returned to its place and fixed with interrupted sutures. 0.1-2% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, transpupillary laser radiation of 661-666 nm large wavelength is applied at a dose of 30-120 J/cm2. the operation is ended with placing sutures on conjunctiva. Platinum, iridium or rhodium are used as the metals of platinum group. The number of electrodes is equal to 4-8. 0.1-1% khlorin solution, selected from group containing photolon, radachlorine or photoditazine, is additionally repeatedly intravenously introduced in 2-3 days at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, repeated laser irradiation of the intraocular neoplasm is carried out with radiation dose of 30-45 J/cm2.

EFFECT: complete destruction of neoplasm; excluded tumor recurrence; reduced risk of tumor cells dissemination.

3 cl, 3 dwg

FIELD: medicine.

SUBSTANCE: the present innovation deals with treating vascular cutaneous neoplasms, such as nevus flammeus and gemangiomas. Light-thermal impact at energy ranged 39-47 J/sq. cm should be performed in two stages, and between them, 2-3 wk after the onset of vascular resistance at the first stage one should perform beta-therapy daily for 2-3 d at single dosage being 20 g. Then, 3 wk later it is necessary to conduct the second stage of light-thermal impact by starting at energy value being 42 J/sq. cm, not less. The method enables to shorten therapy terms due to applying combined method to affect vascular cutaneous neoplasms.

EFFECT: higher therapeutic and cosmetic effect.

1 ex

FIELD: medicine.

SUBSTANCE: method involves intravitreously introducing two electrodes into intraocular neoplasm after carrying out vitrectomy and retinotomy to expose the intraocular neoplasm. The electrodes are manufactured from platinum group metal. Electrochemical destruction is carried out with current intensity of 100 mA during 1-10 min or 10 mA during 10 min in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous laser radiation is carried out in parallel light beam of wavelength equal to 661-666 nm is applied at a dose of 30-120 J/cm2.The transformed retina and tumor destruction products are intravitreally removed. Boundary-making endolasercoagulation of retinotomy area is carried out after having smoothed and compressed retina with perfluororganic compound. The operation is finished with placing sutures on sclerotomy and conjunctiva. Platinum, iridium or rhodium are used as the platinum group metals. Another embodiment of the invention involves adjusting position and size of the intraocular neoplasm in trans-scleral diaphanoscopic way. Rectangular scleral pocket is built above the intraocular neoplasm to 2/3 of sclera thickness with its base turned away from limb. Several electrodes are introduced into intraocular neoplasm structure via the built bed. The electrodes are manufactured from platinum group metal. Electrochemical destruction is carried out with the same current intensity in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. Superficial scleral flat is returned to its place and fixed with interrupted sutures. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg after having carried out vitrectomy and retinotomy. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous laser radiation is carried out in parallel light beam of wavelength equal to 661-666 nm is applied at a dose of 30-120 J/cm2. The transformed retina and tumor destruction products are intravitreally removed using vitreotome. Boundary-making endolasercoagulation of retinotomy area is carried out after having smoothed and compressed retina with perfluororganic compound. The operation is finished with placing sutures on sclerotomy and conjunctiva. Platinum, iridium or rhodium are used as the platinum group metals. The number of electrodes is equal to 4-8.

EFFECT: reduced risk of metastasizing.

4 cl, 13 dwg

FIELD: medicine.

SUBSTANCE: method involves building tunnel to posterior eyeball pole in inferoexterior and superexterior quadrants. The tunnel is used for implanting flexible polymer magnetolaser implant to the place, the subretinal neovascular membrane is localized. The implant has a permanent magnet shaped as a cut ring and is provided with drug delivery system and a short focus scattering lens of laser radiator connected to light guide. The permanent implant magnet is axially magnetized and produces permanent magnetic field of 5-7 mTesla units intensity. It is arranged with its north pole turned towards sclera at the place of the subretinal neovascular membrane projection with extrascleral arrangement of laser radiator lens membrane being provided in the subretinal neovascular membrane projection area. The other implant end is sutured to sclera 5-6 mm far from the limb via holes made in advance. The implant is covered with conjunctiva and retention sutures are placed thereon. Light guide and drug supply system lead is attached to temple with any known method applied. Drugs are supplied via the implant drug supply system in retrobulbary way in any order. Triombrast is given in the amount of 0,4-0,6 ml and dexamethasone or dexone in the amount of 0,4-0,6 ml during 3-4 days every 12 h. 0.1-1% aqueous solution of khlorin is intravenously introduced at the third-fourth day after setting the implant as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, at a bolus dose of 0.8-1.1 mg/kg. Visual control of subretinal neovascular membrane cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the subretinal neovascular membrane with the photosensitizer to maximum saturation level, intravitreous, transretinal laser radiation of 661-666 nm large wavelength is applied at general dose of 30-120 J/cm2. The flexible polymer magnetolaser implant is removed and sutures are placed on conjunctiva. Permanent magnet of the flexible polymer magnetolaser implant is manufactured from samarium-cobalt, samarium-iron-nitrogen or neodymium-iron-boron system material. The photosensitizer is repeatedly intravenously introduced at the same dose in 2-3 days after the first laser radiation treatment. Visual intraocular neoplasm cells fluorescence control is carried out using fluorescent diagnosis techniques. Maximum level of saturation with the photosensitizer being achieved in the subretinal neovascular membrane via laser light guide and implant lens, repeated laser irradiation of the subretinal neovascular membrane is carried out with radiation dose of 30-60 J/cm2.

EFFECT: accelerated subretinal edema and hemorrhages resorption; regression and obliteration of the subretinal neovascular membrane; prolonged vision function stabilization.

6 cl

FIELD: medicine.

SUBSTANCE: method involves filling vitreous cavity with perfluororganic compound. Two electrodes manufactured from platinum group metal are intravitreally, transretinally introduced into intraocular neoplasm. Electrochemical destruction is carried out with current intensity of 10-100 mA during 1-10 min in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous, transretinal laser radiation of 661-666 nm large wavelength is applied at a dose of 30-120 J/cm2 in perfluororganic compound medium. The transformed retina and tumor destruction products are intravitreally removed with perfluororganic compound volume being compensated with its additional introduction. Boundary-making endolasercoagulation of retinotomy area is carried out. The perfluororganic compound is substituted with silicon oil. The operation is ended in placing sutures over sclerotmy areas and over conjunctiva. Perfluormetylcyclohexylperidin, perfluortributylamine or perfluorpolyester or like are used as the perfluororganic compound for filling vitreous cavity. Platinum, iridium or rhodium are used as the platinum group metals.

EFFECT: complete destruction of neoplasm; reduced dissemination risk.

6 cl, 12 dwg

FIELD: medicine, applicable for stopping of pains of various nature.

SUBSTANCE: the device has a quantum-mechanical oscillator located in a casing, magnet, vessel for medicinal agent and a hollow cylinder. The magnet is installed between the oscillator and the vessel. Positioned in the vessel is a hollow cylinder having through holes on its surface.

EFFECT: quick and absolute anestesia.

2 ex, 1 dwg

FIELD: medicine.

SUBSTANCE: method involves administering laser radiation therapy once a day using low intensity pulsating radiation of wavelength equal to 890nmand power density of 0.03 mW/cm2. Injured organ projection to frontal abdominal wall is exposed to radiation at the first laser therapy stage in two fields acting upon each field for 2 min with radiation pulse succession frequency equal to 80 Hz in applying stable contact-type method. Total treatment dose on two fields is equal to 0.008 J/cm2. The second laser therapy stage begins immediately after having finished the first one in applying radiation along the large intestine path using labile contact-type method in a way that radiation pulse succession frequency equal to 80 Hz is applied first during 1 min and then frequencies of 600, 150 and 300 Hz are applied also during 1 min, respectively. Total treatment dose is equal to 0.032 J/cm2 at the second stage. Total treatment dose is equal to 0.04 J/cm2 at both stages.

EFFECT: enhanced effectiveness in inhibiting dysbacteriosis; reduced frequency of postoperative complications.

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