Complex and method of rehabilitation of patients with concomitant vertebral and cardiovascular disease

 

(57) Abstract:

The invention relates to medicines for the rehabilitation of patients with concomitant vertebral and cardiovascular pathology. The proposed group of inventions. Complex rehabilitation of patients with concomitant vertebral and cardiovascular disease includes homeopathic drug “Cralonin and biologically active Supplement “Splat”. The method of rehabilitation of patients with concomitant vertebral and cardiovascular disease is that the patient is given a daily changing at an exponential mode dose homeopathic drug “Cralonin”, then the biologically active Supplement “Splat” and perform a soft traction therapy according to the standard technique. The proposed therapeutic tools allow for purposeful impact on different pathogenetic mechanisms combined vertebral and cardiovascular disease. 2 N. p. F.-ly, 2 tab.

The invention relates to medicines and refers to the complex rehabilitation of patients with concomitant vertebral and cardiovascular disease with the use of homeopathic medicines.

Information theory re system of self-regulation of the organism independently restore the balance. In recent years, proven mechanism of the material effects of homeopathic remedies through the formation of Optimal Nonspecific Adaptive Reactions of the Organism (NARO). These provisions are generally recognized, however, questions about the interaction points homeopathic medicines, tools, physiotherapy and dietary supplements during therapeutic treatment of various pathologies remain open.

The closest known by its technical essence is a method of optimizing drug treatment "Cralonin, including primary control NARO and the formation of installation of the doctor and the patient to achieve by the end of treatment the optimal NARO.

CRALONIN (Cralonin), the production firm “Heel” (Germany) In 100 ml of 45% alcohol solution for oral administration in the form of droplets contains Spigelia anthelmia D2, Kalium carbonicum D3 1 ml matrix of tincture of Crataegus 70 ml; available in bottles dropper 30 and 100 ml. Refers to the sedative, antispasmodic agents. Improves supply of blood and oxygen to the myocardium, regulates blood pressure.

Prescribed for cardiovascular diseases (ischemic heart disease, toxic myocarditis, angina, hypertension, pre - and post-infarction state), “senile behold the night lamp, physical and mental stress).

Apply inside of 10 drops 3 times daily, in acute conditions, 10 drops every 15 minutes (but no more than 2 hours).

Long-term use (several months) should be carried out under the supervision of a physician. (Register of medicines of Russia, 3rd edition, Moscow.: 2000, c.405, Titkov O. C. abstract of dissertation of candidate of med. Sciences. “Blood lipid spectrum and adaptive response in patients with cardiovascular pathology at the sanatorium stage of rehabilitation”, Rostov-on-don, 2000, to 22 C.)

The disadvantage of this method is the narrow focus of therapeutic effects exclusively on the cardiovascular system and the absence of biochemical support, as well as the absence of vertebral pathogenetic mechanisms.

The present invention is to develop a complex and comprehensive rehabilitation of patients with concomitant vertebral and cardiovascular disease in a short period of time and with less cost.

Proposed system for the rehabilitation of patients with concomitant vertebral and cardiovascular pathologies, including homeopathic drug "Cralonin and biologically active Supplement "Splat",different in that the patient is given a daily changing at an exponential mode dose homeopathic drug "Cralonin", then the biologically active Supplement "Splat" and perform a soft traction therapy according to the standard technique.

“Splat” is made from microalgae spirulina platensis grown in environmentally friendly conditions.

"Splat" compensate for vitamin and mineral deficiency, reduces cholesterol and blood sugar, increases the level of hemoglobin, has anti-allergic properties, helps to normalize bowel function, endocrine system. In addition, displays the body of toxins, heavy metals, toxins, radionuclides, normalizes metabolism, stimulates the immune system, prevents the accumulation of excess weight, has hepatoprotective properties, has a tonic effect.

Recommended: as a tonic and to replenish the body with vitamins and trace elements. Dose: 1-2 tablets 3 times a day. Contraindications: individual intolerance to the components (Soloviev A. A., Lyamin M. J., Koveshnikov L. A. Algal energy. M.: Izd-vo MGU, 1997, and 65 C., Pilate T. L., Ivanov A. A. Beanie drug “Splat” on the structure of nonspecific adaptive reactions of the organism (NARO) and the lipid profile of the patients at the sanatorium stage of rehabilitation. Materials of the international scientific conference “Actual problems of development of resorts of the North-West of Russia”, St. Petersburg, April 24-25, 2003 - S. 30-31).

The algorithm for determining NARO and drug administration “Cralonin“ exponential mode.

Criteria adaptive reactions on the signal indicator-percentage of lymphocytes in the leukocyte formula shown in the table. 1.

Reaction training

This is a common nonspecific reaction in response to relatively weak stimuli. For reaction training a characteristic picture in thymicolymphatic, immune and endocrine subsystems of the body coinciding with the lower half of the zone standards (in addition to the secretion of glucocorticoids, which is within the upper half of the zone standards). In the brain - the predominance of soft protective inhibition; active processes of anabolism and catabolism, although anabolism prevails; the processes of accumulation of energy substrates exceed spending and creates energy.

The percentage of lymphocytes - signal indicator is within the lower normal values: 20-27,5%. The level of nonspecific resistance in response to exercise moderately increase is nierownosci - due to active resistance by increasing the activity of protective subsystems of the organism.

Reaction training is accompanied by a mild anti-inflammatory action due to a predominance of secretion of glucocorticoids on mineralocorticoids under normal, moderate functional activity of protective subsystems of the organism.

Biological significance of reaction training - maintaining homeostasis in terms of the weak, insignificant stimuli.

The calm reaction activation

This is a common nonspecific reaction in response to stimuli relative to the average power. For adaptive response tranquil activation of a characteristic picture in thymicolymphatic, immune and endocrine subsystems of the body coinciding with the upper half of the zone standards (in addition to the secretion of glucocorticoids, which is within the lower half of the zone standards); in the brain - the prevalence of moderate excitation. Active processes and catabolism, and anabolism, but anabolic processes prevail.

The level of synchronization of the subsystems of the organism is high when there is high activity of each system.

In the signal indicator - leukocyte formula to the stimulation of regulatory and protective subsystems of the organism, i.e., increases active nonspecific resistance.

The reaction increased activation

This is a common nonspecific reaction to stimuli stronger than for the reaction peaceful activation, but less strong than causing a reaction of stress. For an adaptive response to the increased activation of a characteristic picture in thymicolymphatic, immune and endocrine subsystems of the organism at the level of the upper third of the zone standards and higher (including the secretion of glucocorticoids); the prevalence of significant excitation in the Central nervous system, although, as with calm activation, balance with the processes of inhibition observed with excellent autoregulation. Metabolism: very active processes and catabolism, and anabolism with good balance of flow and fill Energomash substrates. Often a significant predominance of anabolism. The level of synchronization of the operation of the subsystems of the organism is high when there is increased activity of each system.

The signal rate of reaction increased activation from 34 to 40-45% lymphocytes (individually). The resistance increases due to a true stimulation of regulatory and protective subsystems of the organism, it is still higher than in tranquil activation, one is recurrent (see preactivate below). Healthy is the most stable reaction, since the protective system is very active with excellent filling spending and a nice consistency in the work of subsystems.

Biological significance of both reactions activation in an adequate increase in the activity of protective systems in response to the stimulus of the average force, which corresponds to the optimal level of protective response of the organism. When this reaction is most rapid and adequate reconstruction of defenses in response to damage, the rapid healing of wounds or recuperation after illness.

The reaction preactivate

It is not a separate type of adaptive response. This functional condition that occurs when excessive hierarhical and excessive excitation in response to strong effects in organisms, able to respond to such impacts do not stress (that is not a waiver of protection and total activity decline of all subsystems and tissue degeneration), and hyperactivity various subsystems. While too much excitement in the brain excessively increased functional activity of the endocrine glands and thymicolymphatic system; there is hypersynchronization activity subsystems with the failure of the ISM is busy. Increases the rate of spending Energomash substrates, and reproduction gradually behind.

In the leukocyte formula, the percentage of lymphocytes more than 40-45%: lymphocytosis. Resistance varies within very wide limits. One of the factors it can be very high (up to failure - even to most of the factors), and at the same time to other very low. There may be significant resistance to psycho-emotional overload, but the lack of resistance to infections and Vice versa irritability, aggression, sleep disturbance without disturbance of appetite.

Biological significance of preactivation - in an attempt to save the activation in response to excessive load without the "reset" in stress. Preactivate really better stress, but dangerous failure and also is a nonspecific basis of some diseases.

Stress

When stress in the brain sharp excitement turns to development beyond inhibition significantly reduced functional activity thymicolymphatic, immune and endocrine subsystems of the body except ACTH - glucocorticoids, the secretion of which is improved. Metabolism is characterized by the predominance of the processes of catabolism, energy metabolism is the primary objective is on wasteful ways, which leads to the depletion or blocking stocks Energomash substrates, the increase in the share of the processes of glycolysis.

For stress is characterized by severe desynchronization operation of the subsystems on all hierarchical levels of the body. For example, even when typical stress degeneration of lymphoid organs (thymus, lymph node, spleen) can be found in it microcare extreme hyperactivity; or high levels of any mediator, enzyme, or hormone will not be tied to him the mediator, enzyme, hormone, without which the existence of the first is meaningless.

In the leukocyte formula, the percentage of lymphocytes of less than 20% (lymphopenia), acute stress - reasinable and leukocytosis, chronic - eosinophils and leukocytes can be reduced, and high, and normal.

Nonspecific resistance when the stress is reduced. A short-term increase resistance to stress, which, Selye called the "stage of resistance", the discovery of other adaptive responses associated with the development after the stages of anxiety beyond inhibition in the brain. Against the backdrop of such inhibition reduces sensitivity and instead strasti. Therefore, normalization of the activity of the subsystems of the organism and increase of resistance in the so-called "stage of resistance" stress is not due to stress, but due to evolved under these conditions, anti-stress reactions activation or training. The reaction stress is characterized by reduced resistance to various degrees pronounced.

The biological meaning of stress Selye in preserving life at any cost. However, the "price" is often far exceeds the "reasonable limits": not all stressors are a real threat to life, but evolved as a result of stress disrupts the processes of life. Stress - it is a failure of adaptation (in varying degrees of severity depending on the level of reactivity in response to excessive load (internal or external).

General rules of admission of cralonin exponential mode.

The patient is given a bottle of cralonin and an eyedropper. Give mode and instructions for use.

Drops take in the morning, once a day, once after waking up and morning shower until morning exercises, to soul, preferably before shaving, especially to the area and before Breakfast. The activation effect should be the first effect on the body in the morning for šnē day the number of drops drip into the Cup with a SIP of water. The throat size is not important. After taking the drops within 15 minutes you cannot drink, eat, smoke, take any other medications (if there is an acute attack) or food additives. You can do morning exercises, take a shower.

15 minutes after the drops are allowed to eat and drink, allowed to undergo massage. However, to take dietary supplements or herbs, as well as physiotherapy preferably more than half an hour.

Non programmed modes for adults with various diseases brought to the table. 2.

The majority of these modes are given without additional guidance. This means that the specified number of drops refers to undiluted pharmacy drug. In some modes, first specify how many times to breed pharmacy drug.

Drug (alcoholic extract or tincture) was diluted with water, or (in hot seasons) vodka avoid from turning sour. To do this, take one volume of the drug (measure or disposable syringe, or a beaker, or a dessert spoon) and a specified number of volumes of water. With diluted tincture should be treated in the same way as with drugstore: to drip into the Cup with a SIP of water. In the beginning Kaji twice - then add the same volume of water, diluted three times - then add two of the same volume of water, etc.

Then it is desirable to continue the activation therapy at home according to the mode before the end of the schema For this discharge, the patient is given a mode corresponding to its adaptive response at the end of the Spa treatment. The mode can be repeated from beginning to end several times with breaks or without.

Mode№1. 25, 23, 21, 19, 13, 12, 11, 8, 7, 7, 5, 22, 20, 18, 13, 12, 11, 10, 7, 7, 7, 5, 5, 5, 4.

Mode№2. 25, 23, 21, 19, 15, 13, 12, 11, 8, 7, 21, 19, 17, 13, 12, 11, 8, 7, 7, 6, 6, 5, 5, 5, 4.

Mode№3. 25, 23, 21, 23, 21, 19, 21, 19, 17, 19, 17, 12, 12, 11, 12, 11, 7, 7, 7, 5, 5, 5, 4, 4, 4.

Mode№4. 25, 23, 21, 19, 14, 12, 11,11, 10, 10, 7, 6, 21, 19, 11,15, 10, 9, 9, 6, 6, 6, 4, 4, 4.

Mode№5. 20, 18, 16, 1, 10, 9, 6, 5, 4, 20, 18, 13, 12, 11, 10, 7, 7, 5, 16, 14, 12, 11, 8, 7, 7, 5, 5, 5.

Mode№6. 20, 18, 16, 15, 13, 12, 8, 7, 18, 16, 14, 13, 12, 8, 7, 16, 14, 12, 11, 10, 7, 7, 5, 5, 5.

Mode№7. 21, 19, 17, 17, 15, 15, 13, 13, 12, 12, 8, 8, 7, 7, 19, 17, 19, 17, 15, 10, 11, 10, 7, 7, 7, 5, 5, 5.

Mode№8. 20, 18, 13, 12, 11, 10, 7, 20, 18, 16, 15, 10, 9, 9, 6, 6, 17, 15, 10, 9, 9, 8, 7, 7, 7, 5, 5, 5.

Mode№9. 17, 15, 13, 11, 7, 7, 5, 5, 4, 15, 13, 12, 8, 7, 7, 5, 5, 12, 11, 10, 7, 7, 6, 6, 5, 5.

Mode№10. 17, 15, 13, 12, 11, 8, 7, 7, 6, 6, 5, 15, 13, 12, 11, 8, 7, 7, 6, 6, 5, 5, 4, 4, 3.

Mode№11. 17, 15, 13, 12, 12, 8, 8, 7, 7, 5, 5, 5, 15, 13, 12, 8, 8, 8, 7, 7, 7, 5, 5, 5, 5.

Mode№12. 25, 23, 21, 15, 13, 12, 8, 7, 25, 23, 21, ">Mode№14. 25, 23, 21, 15, 13, 11, 12, 11, 10, 11, 10, 7, 8, 7, 7, 21, 19, 19, 13, 13, 11, 12, 11, 10, 10, 7, 7, 5, 5.

Mode№15. 22, 20, 18, 16, 11, 10, 9, 6, 20, 18, 16, 14, 9, 8, 7, 5, 18, 16, 14, 12, 8, 7, 7, 5, 5.

Mode№16. 20, 18, 16, 14, 10, 9, 8, 7, 18, 16, 14, 10, 9, 8, 7, 15, 13, 12, 11, 8, 7, 6, 5, 5, 4, 4.

Mode№17. 25, 23, 21, 19, 15, 13, 15, 13, 12, 11, 12, 11, 10, 11, 10, 9, 10, 9, 8, 8, 7, 7, 7, 5, 5, 5.

Mode№18. 18, 16, 14, 10, 9, 8, 7, 5, 5, 4, 4, 3, 3, 15, 13, 11, 10, 7, 7, 5, 5, 5, 4, 4, 3, 3.

Mode No. 19. A pharmaceutical preparation to breed twice(1+1): 32, 29, 26, 24, 18, 16, 14, 10, 9, 28, 25, 23, 21, 16, 14, 12, 11, 8, 7, 7, 5, 5, 4, 3.

Mode№20. 18, 16, 14, 10, 11, 10, 9, 10, 9, 8, 9, 8, 7, 7, 5, 5, 5, 15, 15, 10, 9, 10, 7, 7, 5, 5, 5

Mode№21. 17, 15, 13, 12, 8, 7, 7, 5, 5, 4, 4, 3, 3, 15, 13, 12, 11, 7, 7, 5, 5, 5, 4, 4, 3.

Mode No. 22. A pharmaceutical preparation to breed twice(1+1): 30, 27, 24, 22, 17, 15, 13, 12, 9, 8, 26, 23, 21, 16, 14, 12, 11, 8, 22, 20, 18, 16, 12, 11, 10, 7, 7.

Mode№23. 16, 14, 10, 11, 10, 9, 10, 9, 8, 8, 9, 8, 7, 7, 7, 5, 5, 5, 4, 4, 4, 4, 3, 3.

Mode No. 24. A pharmaceutical preparation to breed twice(1+1): 28, 25, 22, 16, 14, 12, 11, 7, 7, 6, 28, 25, 23, 16, 14, 12, 8, 8, 7, 7, 6, 6, 6.

Mode No. 25. A pharmaceutical preparation to breed twice(1+1): 28, 25, 23, 21, 16, 14, 12, 11, 8, 7, 6, 25, 23, 21, 16, 14, 12, 11, 10, 7, 7, 6, 6.

Mode№26. 14, 12, 11, 10, 10, 7, 7, 5, 5, 4, 4, 4, 14, 12, 11, 8, 8, 7, 7, 5, 5, 4, 4, 4.

The invention is illustrated by the following examples:

EXAMPLE 1

Man K., 39 years old, a soldier. He entered the sanatorium treatment with a diagnosis of Neurocirculatory on the primary area in Art. unstable remission. Condition after suffering (more than 10 years ago) closed craniocerebral injury. Alimentary obesity 2-tbsp.”.

Upon receipt complained of irritability, poor sleep, fatigue, shortness of breath, decreased recently portability neuro-emotional and physical stress that occurs after overloads pain behind the breastbone, which periodically takes nitroglycerin, as well as dizziness, pain in the lumbar spine. The worsening of his condition relates to unresolved financial and domestic problems that arose after graduating at the Academy of the Ministry of defense and the arrival to a new place of service.

Objective: Growth 176 see Weight - 98 kg HELL - of 145/90 mm RT.article HR - 76-82 beats per 1 minute sinus tachyarrhythmia. NARO - reaction preactivation. Cholesterol 7,72 mmol/l calcium Levels in the plasma - 9.0 mg/DL, the level of magnesium 1.7 mg/DL, the level of iron and 75.5 ág/DL. AST - 42,7 units/l, CRP is 1.0. Glucose - 5.1 mmol/L. Other indicators within the physiological norm.

Assigned to: Health mode No. 1-3 days, then the mode No. 2. Diet No. 10 with fasting days (kefir) 1-2 per week, Galatasaray on toniziruushii mode, gym, relaxing herbal tea 3 R/day, p is salonin regime No. 2, (Mode№2. 25, 23, 21, 19, 15, 13, 12, 11, 8, 7, 21, 19, 17, 13, 12, 11, 8, 7, 7, 6, 6, 5, 5, 5, 4.)

Splat on 3 tables. 3 R/day.

Traction therapy therapeutic mate “Detensor” No. 18, every day for 35-40 minutes

After treatment of complaints virtually no presents, notes the increase in the overall tone, normalization of sleep, the disappearance of dyspnea, weakness, chest pain. The reduced weight 2.7 kg increased growth of 1.2 see AD - 125/80 mm RT. Art. heart rate is 72 beats per 1 minute ECG sinus rhythm, right. NARO - reaction of increased activation. Decreased cholesterol up of 5.05 mmol/l Increased the content in plasma calcium (to 10.3 mg/DL), magnesium (up to 2.1 mg/DL), iron (to 89.3 mg/DL). The normalized content of the ACT (to 22.7 units/l), CRP (0), glucose (up to 4.3 mmol/l). Recommendations for follow-up treatment of cralonin in mode # 2, the reception splat in table 2. 3 R/day after meals.

After 6 months (postal questionnaire). NARO - calm activation, no complaints, was not in pain, exacerbation of existing diseases was not. The weight has not increased, the growth rate of discharge from the sanatorium, allopathic medicines did not accept.

EXAMPLE 2

Male R. ' 73, retired MO. He entered the sanatorium treatment with a diagnosis of Ischemic heart disease, staros spine common with a primary lesion of the lumbar region in Art. unstable remission. Condition after fracture (more than 55 years ago) of the lumbar spine”.

Upon receipt complained of constant noise in the ears, impaired sleep, weakness, shortness of breath, fell sharply in the last time tolerability neuro-emotional and physical stress, dizziness, frequent pain in the chest, pain in all parts of the spine, reduction in connection with motor activity.

Objective: height 170 see Weight - 68 kg HELL - 155/95 mm RT.article Heart rate of 78 beats per 1 min, sinus rhythm. NARO - response training. Cholesterol 6,24 mmol/l calcium Levels in the plasma of 6.7 mg/DL, the level of magnesium 2.5 mg/DL, the level of iron and 63.4 ág/DL. AST - 11,1 units/l CRP - 2,0, glucose - 5.3 mmol/l

Appointed: Sanatorium "mode 1".

Diet number 10. Galatasaray low mode, relaxing herbal tea 3 R/day after meals. Baths with lavender and eucalyptus to alternate every other day. Mineral water “lasarevskoye” 100,0 3 R/day for 30 minutes before eating. Enap 1 tab. 3 R/day, nitroglycerin with strokes.

Cralonin mode No. 20 (№20. 18, 16, 14, 10, 11, 10, 9, 10, 9, 8, 9, 8, 7, 7, 5, 5, 5, 15, 15, 10, 9, 10, 7, 7, 5, 5, 5).

Splat in table 2. 3P/day.

Traction therapy treatment maté De the corresponding tone, improved sleep, a clear reduction in dyspnea, practical disappearance of weakness and chest pain. Weight 1.3 kg increased growth by 0.5 see HELL - of 145/90 mm RT. Art. heart rate is 72 beats per 1 minute ECG sinus rhythm, right. NARO - calm reaction activation. Decreased cholesterol levels to 4,94 mmol/L. Content in plasma calcium was not changed (6,7 mg/DL), the normalized level of magnesium (up to 2.3 mg/DL), increased iron content (up to 99.6 mg/DL). The normalized content of the ACT (to 19.2 units/l), CRP (0), glucose (up to 4.6 mmol/l). Recommendations for follow-up treatment of cralonin mode No. 20, the reception splat in table 2. 3 R/day after meals.

After 6 months (postal questionnaire). NARO - calm activation, complaints on the level of discharge from the sanatorium, sharply reduced nitroglycerine, a reduced dose of Enap - up to 1 tab./day, exacerbation of the main disease was not, other allopathic medicines did not accept.

EXAMPLE 3

Woman L, 76 years, family member, retiree MO. He entered the sanatorium treatment with a diagnosis of Coronary heart disease, angina II FK Atherosclerotic myocardiocytes. Osteochondrosis common”. Upon receipt predavariynyh and physical activity, dizziness, pain in the chest, pain in the spine, the cervical-thoracic Department, the reduction in connection with motor activity.

Objective: Growth 161 see Weight - 63 kg HELL - 150/100 mm RT.article Heart rate is 80 BPM 1 min, sinus rhythm, the blockade of the right bundle branch, signs of myocardial ischemia and hypertrophy of the left ventricle. NARO - stress. Cholesterol 10,48 mmol/l calcium Levels in the plasma of 8.7 mg/DL, the level of magnesium 1.6 mg/DL, the level of iron of 51.7 µg/DL. AST - a 12.7 units/l CRP - 0. Glucose - 4.5 mmol/l

Assigned to: Health mode No. 1. Diet number 10. Galatasaray low mode, relaxing herbal tea 3 R/day after meals. Baths with eucalyptus in a day, a gentle massage of the cervical spine No. 10. Mineral water “lasarevskoye” 100,0 3 R/day 30 min before meals, Riboxin 1 tab. 3P/day, nitroglycerin with strokes.

Cralonin mode No. 18 (Mode№18. 18, 16, 14, 10, 9, 8, 7, 5, 5, 4, 4, 3, 3, 15, 13, 11, 10, 7, 7, 5, 5, 5, 4, 4, 3, 3.

Splat in table 2. 3 R/day.

Traction therapy therapeutic mate “Detensor” No. 20, every day for 35-40 minutes

After treatment of complaints has declined, notes the growth in the overall tone, better sleep, a significant decrease in shortness of breath, weakness and chest pain. Weight increased n is th, the reduction of signs of myocardial ischemia. NARO - response training. Decreased cholesterol levels to 5,98 mmol/L. the plasma blood calcium increased (10,2 mg/DL), the normalized level of magnesium (up to 2.5 mg/DL), increased iron content (up to 101,7 µg/DL). The normalized content of the ACT (to 12.1 units/l), CRP (0), glucose (up to 4.0 mmol/l). Recommendations for follow-up treatment of cralonin on No. 18, the reception splat in table 2. 3 R/day after meals.

After 6 months (postal questionnaire). NARO - calm activation, complaints on the level of discharge from the sanatorium, has dramatically reduced the nitroglycerine. Exacerbation of the main disease was not, other allopathic drugs was not accepted.

EXAMPLE 4

The Century man, 23 years old, a family member of a soldier. He entered the sanatorium treatment with a diagnosis of Neurocirculatory dystonia of mixed type. Cervicalgia unknown etiology”.

Upon receipt complained of irritability, poor sleep, fatigue, decreased recently portability neuro-emotional and physical stress, as well as dizziness and pain in the cervical spine. The worsening of his condition associates with fatigue after passing the state exams and postupy. NARO - reaction preactivation. Cholesterol 6,36 mmol/l calcium Levels in the plasma of 8.7 mg/DL, the level of magnesium 1.2 mg/DL, the level of iron and 47.5 mg/DL. AST - 32,7%/l CRP - 1,0. Glucose - 4,6 mmol/L. Other indicators within the physiological norm.

Assigned to: Health mode No. 1 - 3 days, then the mode No. 2. Diet No. 15, Galatasaray on the toning regime, exercising in the gym, relaxing herbal tea 3 R/day after meals. Bath with lavender in a day. Mineral water “lasarevskoye” 100,0 3 R/day 30 minutes before meals.

Cralonin mode No. 19 (Mode No. 19. A pharmaceutical preparation to breed twice(1+1): 32, 29, 26, 24, 18, 16, 14, 10, 9, 28, 25, 23, 21, 16, 14, 12, 11, 8, 7, 7, 5, 5, 4, 3.)

Splat on 3 tables. 3 R/day.

Traction therapy therapeutic mate “Detensor” No. 18, every day for 35-40 minutes

After treatment of complaints virtually no presents, notes the increase in the overall tone, normalization of sleep, the disappearance of weakness. Weight increased by 2.8 kg increased growth of 1.5 see AD - 115/75 mm RT. Art. heart rate of 68 beats per 1 minute ECG sinus rhythm, right. NARO - reaction of increased activation. Decreased levels of cholesterol up to 5.93 mmol/l Increased the content in plasma calcium (up to 9.3 mg/DL), magnesium (up to 2.3 mg/DL), iron (up to 76.4 ág/DL). Norma of cralonin mode No. 19, receiving splat in table 2. 3 R/day after meals.

After 6 months (postal questionnaire). NARO - increased activation, no complaints, was not sick, allopathic medicines did not accept.

Clinical trials show that the proposed therapeutic tools allow for purposeful impact on different pathogenetic mechanisms combined vertebral and cardiovascular disease.

1. Complex rehabilitation of patients with concomitant vertebral and cardiovascular pathology, characterized in that it includes homeopathic drug “Cralonin and biologically active Supplement “Splat”.

2. The method of rehabilitation of patients with concomitant vertebral and cardiovascular disease, characterized by the fact that the patient is given a daily changing at an exponential mode dose homeopathic drug “Cralonin”, then the biologically active Supplement “Splat” and perform a soft traction therapy according to the standard technique.

 

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The invention relates to new derivatives chromanone and chromanone selected from the group comprising: ethyl ester of (2S)-3-{2-[3-(1H-imidazol-2-ylamino)propyl]-4-oxo-4H-chromen-6-yl]-2-(2,2-dimethylpropanamide)propionic acid, (2S)-3-[2-[3-(1H-imidazol-2-ylamino)propyl]-4-oxo-4H-chromen-6-yl}-2-(2,2-dimethylpropanamide)propionic acid, (2S)-3-[2-[3-(pyridine-2-ylamino)propyl]-4-oxo-4H-chromen-6-yl}-2-(2,2-dimethylpropanamide)propionic acid, (2S)-3-{2-[3-(pyridine-2-ylamino)propyl]-4-oxo-4H-chromen-6-yl}-2-butylcyclopentadienyl acid, (2S)-3-{2-[3-(pyridine-2-ylamino)propyl]-4-oxo-4H-chromen-6-yl}-2-benzisothiazolinone acid, and also their physiologically acceptable salts, enantiomers or diastereomers

The invention relates to new derivatives of benzopyran formula (I)

where R1and R2each independently represent a hydrogen atom, a C1-6-alkyl group, where this alkyl group may be optionally substituted by a halogen atom, a C1-6-alkoxygroup or a hydroxyl group; R3represents a hydroxyl group or a C1-6-alkylcarboxylic; R4represents a hydrogen atom, or R3and R4together form a bond, m is an integer from 0 to 4, n represents an integer from 0 to 4, Y is absent or represents CR11R12where R11and R12each independently represents a hydrogen atom or a C1-6is an alkyl group, R5represents an aryl group or heteroaryl group, such as thienyl, pyridyl or indolyl, where this aryl group may be optionally substituted(R10), where R10represents a halogen atom, a hydroxyl group, a C1-6-alkyl group, where this alkyl group may be optionally substituted by atom galactography, di-C1-6-alkylamino, C1-6-alkoxycarbonyl group, carboxyl group, q is an integer from 1 to 3, and each R10may be the same or different when q is 2 or 3, R6represents a hydrogen atom or a C1-6is an alkyl group, R10represents a hydrogen atom or a C1-6is an alkyl group, X is absent or represents C=O or SO2; R8represents a hydrogen atom, a C1-6-alkyl group, where this alkyl group may be optionally substituted by a halogen atom, or WITH3-6-cycloalkyl group, and R9represents a halogen atom, a nitro-group, or cyano; or their pharmaceutically acceptable salts, as well as a drug on the basis of these compounds with anti-arrhythmic activity

The invention relates to medicine, namely to breast care, gynecology, endocrinology

The invention relates to the field of medicine, biology, physiology, politicologie and is intended to reduce the content and excretion of uric acid from the body

The invention relates to the field of drug biomass of spirulina

Medical-cosmetic // 2230546
The invention relates to the field of drugs of natural origin
The invention relates to pharmaceutical, cosmetic and food industry

The invention relates to medicine and can be used as a complex chemoradiation therapy for treatment and prevention of food-based dietary supplements containing activated natural antioxidants

The invention relates to the field of biotechnology, microbiological and pharmaceutical industries

The invention relates to medicine, namely to the creation of drugs of natural origin for the treatment of diseases of the thyroid gland

The invention relates to medicine, namely to breast care, gynecology, endocrinology
The invention relates to medical, pharmaceutical and food industries

FIELD: medicine, pharmaceutical, cosmetic and food industry.

SUBSTANCE: method involves destruction and hydrolysis of alga taken among the group including: laminaria, zooster and focus followed by separating the cytoplasmatic fraction and addition of food acid polyvalent metal salt. Then correction of acidity is carried out to obtain pH = 5-7 followed by drying and conversion of fraction to form useful for storage by sterilization or freezing, or drying, or preserving. The food acid polyvalent metal an aqueous solution is added preferably in the amount 0.75% of preparation mass. Invention provides expanding functional capacity of the preparation with respect to stimulation of processes in healing wounds and burns, regeneration of post-traumatic damages, oncoprotecting and photo-sensitizing activity with respect to cancer cells at maximal absorption of light radiation in the region 630-770 nm.

EFFECT: improved producing method, valuable medicinal properties of preparation.

11 cl, 3 ex

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