A method for the treatment of focal alopecia

 

(57) Abstract:

The invention relates to medicine, and dermatology. Spend pharmacotherapy. Realize the impact of electric current on the reflex zones and biologically active points. Use the reflex zones of the projection area of the upper cervical sympathetic nodes, spine, areas of the face, the projection zones of the liver. Exposure is carried out for 10 days. The parameters of the electric current and the zone of influence developed for each treatment session. The method reduces the number of relapses and complications. 2 C.p. f-crystals.

The invention relates to medicine, dermatology, specifically to methods for treating alopecia baldness.

Known methods of treatment of this disease consist in the appointment of physiotherapy in the form of CMT (sinusoidal modulated currents) [1], d Darsonvalization [1], photochemotherapy [2], cryo [3], electrosleep, electrophoresis, EHF-therapy (electromagnetic waves of millimeter range of extremely high frequency), laser therapy [2, 4], transcranial electrical stimulation [5], as well as pharmacotherapy with the use of drugs. The latter are used in the form of local (local irritant, plumularia, psychotropic drugs, hormones, immunosuppressants) [6-18].

However, despite the large number of proposed methods of treatment of this disease is often resistant to therapy and relapse, which is a clinical problem [19].

In addition, most treatment methods have drawbacks. So, physiotherapeutic methods are contraindicated in many diseases, often cause side effects that require repeated repeated courses of treatment [1-5].

The use of pharmacological means also has a number of disadvantages. Medicines need to be used long-term, some in the form of injections, possible adverse and allergic reactions [6-18].

Medical treatment is expensive due to the duration of application and the simultaneous use of multiple drugs, especially in combination with physiotherapy treatment.

Closest to the present invention is a method for the treatment of focal alopecia, including pharmacotherapy and reflexogenic zones [20]. This method of treatment is not sufficiently effective against drug-resistant forms of the disease.

New technical semeneya.

The task to solve a new method for the treatment of focal alopecia, including pharmacotherapy and reflexogenic zones pulsed bipolar current, 1 times a day, for 10 days, and on the first day affect the spine area and to areas of the face with the current frequency of 59.3 Hz, for a total duration of 15-20 minutes to the center of baldness with the current frequency from 20 to 100 Hz with a duration of 1 minute; on the second day - cervical-collar zone with the current frequency of 59.3 Hz, with a duration of 15-20 minutes on the upper cervical sympathetic nodes with the current frequency from 15 to 60 Hz, duration 1 minute on each side; on the 3rd day of the spine area and to areas of the face with the current frequency from 20 to 100 Hz, for a total duration of 15-20 minutes to the center of baldness with the current frequency of 59.3 Hz, a duration of 5 minutes; 4-th day to the region of the liver with the current frequency of 59.3 Hz, with a duration of 15-20 minutes, at the upper cervical sympathetic nodes with the current frequency from 30 Hz to 120 Hz, the duration of pauses between pulses in a packet 1200 μs, the duration to 5 minutes on each side; on the 5th day - cervical-collar zone with the current frequency from 20 to 100 Hz, for a total duration of 15-20 minutes to the center of baldness with the current frequency of 59.3 Hz, prodolzhitelnost 15-20 minutes on the upper cervical sympathetic nodes with the current frequency from 15 to 60 Hz, duration 1 minute on each side; on the 7th day to the region of the liver with the current frequency from 20 to 100 Hz, for a total duration of 15-20 minutes to the center of baldness with the current frequency of 59.3 Hz, a duration of 5 minutes; 8-th day - cervical-collar zone with the current frequency of 59.3 Hz, with a duration of 15-20 minutes, at the upper cervical sympathetic nodes with the current frequency from 30 Hz to 120 Hz, the duration of pauses between pulses in a packet 1200 μs, 5 minutes on each side; on the 9th day of the spine area and to areas of the face with the current frequency from 20 to 100 Hz, for a total duration of 15-20 minutes to the center of baldness with the current frequency of 59.3 Hz, a duration of 5 minutes; on the 10th day of the spine area and to areas of the face with the current frequency of 59.3 Hz, for a total duration of 15-20 minutes, at the upper cervical sympathetic nodes with the current frequency from 15 to 60 Hz, 5 minutes on each side, repeat the treatment after two months, the scope of the spine includes the line of the spinous processes and paravertebral lines, and areas of the face include the three branches of the trigeminal nerve: ophthalmic nerve, the maxillary nerve and the mandibular nerve.

The zone of influence of electric pulses specified characteristics determined by the following anatomical boundaries:

- spine area includes the line of the spinous processes and paravertebral lines;

- zone of the face include the three branches of the trigeminal nerve on the face on both sides: the ophthalmic nerve is the top edge of the orbit; maxillary nerve is the lower edge of the orbit; the mandibular nerve at the angle of the mouth;

- cervical-collar region is bounded from above by a line of hair growth, bottom - upper blade spines on the sides - clavicle-acromiale joints;

- the projection area of the liver is determined by its percussion borders;

- hearth alopecia detected visually;

- the area of projection of the upper cervical sympathetic nodes located on Provinciale to tingling. Duration effects on tonic reflex zones (cervico-thoracic area of the spine area, areas of the face and the projection area of the liver) during the session is 15-20 minutes; on the hearth alopecia - up to 5 minutes; on the area of projection of the upper cervical sympathetic nodes - up to 5 minutes on each side. In the subsequent course of treatment is repeated after 2 months on this scheme. In severe forms of the disease (Subtotal alopecia) reflexogenic zones combined with traditionally used medicinal therapy (ascorbic acid, zinc oxide, Niacin, sodium thiosulfate, trental, external treatment).

Diagram of the electrical impulses of the above characteristics on the reflex zones of the body for the treatment of focal alopecia is as follows:

day 1:

- spine area (along the line of the spinous processes and paravertebral lines), the area of the face (the ophthalmic, maxillary and mandibular nerves): current frequency - of 59.3 Hz, total duration - 15-20 minutes;

- the hearth of hair loss: current frequency from 20 to 100 Hz, duration 1 minute.

day 2:

- cervical-gate is s: current frequency - from 15 to 60 Hz, duration 1 minute on each side.

day 3:

- spine area, areas of the face: the current frequency from 20 to 100 Hz, the total duration of 15-20 minutes,

- the hearth of hair loss: current frequency - of 59.3 Hz, a duration of 5 minutes.

day 4:

- the region of the liver: current frequency - of 59.3 Hz, a duration of 15-20 minutes;

- the upper cervical sympathetic nodes: current frequency from 30 Hz to 120 Hz, the duration of pauses between pulses in a packet 1200 μs, the duration - 5 minutes on each side.

day 5:

- cervical-collar zone: current frequency from 20 to 100 Hz, a duration of 15-20 minutes;

- the hearth of hair loss: current frequency - of 59.3 Hz, a duration of 5 minutes.

day 6:

- spine area, zone entity: current frequency - of 59.3 Hz, total duration 15-20 minutes;

- the upper cervical sympathetic nodes: current frequency from 15 to 60 Hz, duration 1 minute on each side.

day 7:

- the region of the liver: current frequency from 20 to 100 Hz, a duration of 15-20 minutes;

- the hearth of hair loss: current frequency - of 59.3 Hz, a duration of 5 minutes.

day 8:

- cervical-Vorotnikov is state current - from 30 to 120 Hz, the duration of pauses between pulses in a packet 1200 μs, the duration - 5 minutes on each side.

9th day:

- spine area, areas of the face: the current frequency from 20 to 100 Hz, a duration of 15-20 minutes,

- the hearth of hair loss: current frequency - of 59.3 Hz, a duration of 5 minutes.

10th day:

- spine area, zone entity: current frequency - of 59.3 Hz, total duration 15-20 minutes;

- the upper cervical sympathetic nodes: current frequency from 15 to 60 Hz, duration - 5 minutes on each side.

Selection of areas and species effects on the reflex zones of the human body electrical impulses of the specified characteristics for the treatment of focal alopecia attributable to the following:

- stimulation of physical stimuli, including electrical signals of the above mentioned characteristics, reflexogenic zones of the cervico-thoracic area, the area of the spine, areas of the face and the area of projection of the liver have a restorative effect on the body, and helps to restore homeostasis [20-22];

- the impact of physical stimuli, including electrical signals of the above mentioned characteristics, the area of projection SS="ptx2">

"our impact on the area of projection of the upper cervical sympathetic nodes because these nodes implement the autonomic innervation of the scalp [24]. In turn, it is known that stimulation of the projection area of the upper cervical sympathetic nodes (e.g. ITC) increases blood flow and improves trophic tissues of the head, which improves hair growth [1].

In the implementation of impact on the body's electrical impulses above the specified characteristic participate as a local reflex mechanisms, and the General reaction of an organism to the action of external factors [21-23].

The local effect of electric pulses is the activation processes of microcirculation and improve the trophic tissue not only in the area of local impact (moderate persistent hyperemia), but also in the internal organs that are associated with this area of the skin (cutaneous-visceral reflex): increase in pulse blood vessels, reducing vascular tone, improving venous outflow.

The overall effect on the body's electrical impulses activate the non-specific defense mechanisms, as evidenced by:

- have ageusia in optimizing the performance of the immune system by increasing the number of T-active lymphocytes, normalization of the balance of immunoglobulins, the recovery ratio of T-killer cells and T-suppressor cells, increasing the number of b-lymphocytes and total content of immunoglobulins;

optimization of the ratio of the tone of the sympathetic and parasympathetic divisions of the autonomic nervous system.

The mode of exposure, it is time and consistency on reflexogenic zones of the cervical area of the spine, the liver, the source of baldness and the upper cervical sympathetic nodes bipolar pulse electric current that causes hair growth in alopecia alopecia, selected on the basis of clinical observations for this category of patients.

The proposed method of treatment was treated 15 patients with focal alopecia. Of them women (aged from 10 to 37 years) was 46.7%. Men (ages 16 to 45 years) was 53.3%.

Clinical observations on the use of pulsed bipolar current for the treatment of focal alopecia showed that during the first month after treatment, all the patients showed abundant growth of lanugo hair in the centers, and within the next 3 months - growth long hair. Within 1 year after the treatment was not zaregistriruiusi the proposed method of treatment and the feasibility of their use for the treatment of focal alopecia.

Clinical example (extract from the history of the disease). Patient C., age 10, has addressed in clinic of dermal illnesses Siberian state medical University, 4 June 2002 with complaints of hair loss in the form of multiple lesions on the scalp. Sick since June 2001.

Local status. The pathological process is common noninflammatory nature involving the scalp (temporal, parietal and occipital regions). Pathological elements represented by foci of irregular shape with a size from 2 to 17 see In some pockets of the hair is completely missing, others are tiny and long hair. Visible mouth of the hair follicles. The skin in the pockets of ordinary paint, no atrophy. Hair is easily emilyrose throughout the scalp. According to the results of further examination revealed:

- the CBC on June 4, 2002 - erythrocytes - 4,51012Hb - 150 g/l, leucocytes - 6,9109, lymphocytes - 37%, monocytes - 2%, segmented - 58%, eosinophils -3%, ESR - 2 mm/h;

biochemical analysis blood on June 4, 2002 - glucose - 4.3 mmol/l, bilirubin total - 13.3 mmol/l, total protein - 72 g/l;

- urinalysis on June 4, 2002: the color of straw, proseline, epithelium - 2-3 in eyeshot, leukocyte - 1-3 in the field of view;

- Wasserman (RW) and sedimentary response is negative;

- ultrasound examination of abdominal cavity organs from June 7, 2002: echo skopicki without pathology;

- immunofluorescence assay (ELISA), 26 June 2002: antibodies to opisthorchis not detected; antibodies to Giardia - a titer of 1:300.

Based on the results of the examination diagnosed with alopecia alopecia, severe form.

The patient received the following treatment: zinc oxide 0.05 g 2 times a day, nicotinic acid 1% - 1 ml/m 1 time per day No. 10, ascorbic acid 5% - 1 ml/m 1 time per day No. 10, pyridoxine hydrochloride 6% - 1 ml/m 1 time per day No. 10, reflexogenic zones bipolar pulse current according to the formula of the invention to the indicated mode apparatus for physical therapy SCENAR 97.4+”.

At the end of treatment visible changes were observed. At the control examination after 1 month - abundant growth of lanugo hair in all places. When viewed through 3 months - abundant growth of long and lanugo hair in all places.

The proposed method of treatment meets the criterion of “industrial applicability”, since it is uspekha University and MUE Clinic checkups” ,Tomsk.

Thus, the proposed method for the treatment of focal alopecia can achieve a stable clinical effect in patients with focal alopecia mild, severe and resistant forms, as well as to reduce the frequency of relapses and complications. This, of course, determines the proposed method of treatment as more effective than the present known methods of treatment of this disease. In addition, non-invasiveness of the proposed method, no side effects and complications to widely use this method of treatment, all patients presenting with about focal alopecia, both in an inpatient and outpatient basis.

Sources of information

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2. Mikhailova N. In., Arakcheev A. P. Complex method of treatment of alopecia areata in children with the use of low-intensity laser radiation and external photosensitizers // journal of dermatology and venereology. - 1994. No. 4. - S. 50.

3. Arutyunov C. J., Gutman, S. E. experience in the treatment of some of the hair loss liquid nitrogen and Lee-neon laser in the treatment of patients with alopecia // Kazan medical journal. - 1991. - So 72, No. 4. - S. 297-298.

5. Samsonov C. A., Rezaikina A. C., Myagkova, M. A., Volnuhin C. A., N. Kharitonova.And., Gryshchenko A. P., Tsaregorodtseva E. E., Kovalenko Y. Y. Transcranial electrical stimulation of subcortical brain structures in complex treatment of patients with alopecia areata // journal of dermatology and venereology. - 2000. No. 2. - S. 59.

6. Samsonov C. A., Markushev L. I., Fomkin, I., volnuhin C. A., Tsaregorodtseva E. E. Therapy of patients with alopecia areata taking into account the rheological reagents and coagulation of blood // the journal of dermatology and venereology. - 2000. No. 3. - S. 76.

7. Tsvetkov, M., Samsonov C. A., Sirchenko M. A. Influence verapamilo ointment on the morphology of the hair follicles of the skin of Guinea pigs // journal of dermatology and venereology. - 1999. No. 1. - S. 65.

8. Suvorov K. N., Gadzhigoroeva A., alopecia areata. Part 3. Treatment // journal of dermatology and venereology. - 1999. No. 2. - S. 76.

9. Popov A. E., Anisimov I. I., Rubin C. C., Kuznetsov, S., Bender, K. I., Durain K. C., Elastin - a new tool for the treatment of hair loss // journal of dermatology and venereology. - 1994. No. 6. - C. 35.

10. Suvorov K. topical application of diphencyprone for the treatment of alopecia areata: assessment of the 48 cases after 30-month follow-up //ysenia // journal of dermatology and venereology. - 1992. No. 3. - S. 54-56.

12. Sagnes I. E. the Application of timisora and glycyram in treatment of alopecia baldness // journal of dermatology and venereology. - 1993. No. 5. - S. 41-43.

13. Wachtmeister I. J., Ryabinina M. E., Dandashi A. M. Centeral in the treatment of various forms of hair loss // journal of dermatology and venereology. - 1993. No. 4. - S. 62-64.

14. Sheeva O. F., Isupov, I. C., Anisimov, I. assessment of the safety of the juvenile Palastina // journal of dermatology and venereology. - 1994. No. 4. - S. 8-10.

15. Volkov, P. C., Kalmykova I.e., Alekseev, K. C. Means local action for the treatment of various forms of alopecia // Medical care. - 1997. No. 2. - S. 32-35.

16. Fomkin I. G., Auerbach B. C. Alopecia alopecia: clinical features and treatment // Russian medical journal. - 1997. No. 4. - S. 34-36.

17. Gonchar N. In., Sokolov, M. I., N. Muraviev.N., Melnikova I. Y. and other Efficiency sapropel in the treatment of children suffering from alopecia // Medical-social problems of health care in transition to insurance medicine. - SPb., 1992. - S. 123-125.

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1. A method for the treatment of focal alopecia, including pharmacotherapy and reflexogenic zones, characterized in that the effect of pulsed bipolar current, 1 times a day, for 10 days, and on the first day affect the spine area and to areas of the face with the current frequency of 59.3 Hz, for a total duration of 15-20 min, the focus of baldness with the current frequency from 20 to 100 Hz, duration 1 min; on the second day - on a neck collar--the area with the current frequency of 59.3 Hz, with a duration of 15-20 min, on the upper cervical sympathetic nodes with the current frequency from 15 to 60 Hz, duration 1 minimalnosti 15-20 min, the focus of baldness with the current frequency of 59.3 Hz, a duration of 5 min; 4-th day to the region of the liver with the current frequency of 59.3 Hz, with a duration of 15-20 min, the upper cervical sympathetic nodes with the current frequency from 30 Hz to 120 Hz, the duration of pauses between pulses in a packet 1200 μs, the duration of 5 min on each side; on the 5th day - cervical-collar zone with the current frequency from 20 to 100 Hz, for a total duration of 15-20 min, the focus of baldness with the current frequency of 59.3 Hz, duration: 5 min; 6-th day - on the spine area and to areas of the face with the current frequency of 59.3 Hz, for a total duration of 15-20 min, the upper cervical sympathetic nodes with the current frequency from 15 to 60 Hz, duration 1 min on each side; on the 7th day to the region of the liver with the current frequency from 20 to 100 Hz, for a total duration of 15-20 min, the focus of baldness with the current frequency of 59.3 Hz, a duration of 5 min; on the 8th day - cervical-collar zone with the current frequency of 59.3 Hz, with a duration of 15-20 min, the upper cervical sympathetic nodes with the current frequency from 30 Hz to 120 Hz, the duration of pauses between pulses in a packet 1200 μs, duration 5 min on each side; on the 9th day of the spine area and to areas of the face with the current frequency from 20 to 100 Hz, the total length of the well and on areas of the face with the current frequency of 59.3 Hz, the total duration of 15-20 min, the upper cervical sympathetic nodes with the current frequency from 15 to 60 Hz, with a duration of 5 min on each side, repeat the treatment after two months.

2. The method according to p. 1, characterized in that region of the spine includes the line of the spinous processes and paravertebral lines.

3. The method according to p. 1, characterized in that the zones of the face include the three branches of the trigeminal nerve: ophthalmic nerve, the maxillary nerve mandibular nerve.

 

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SUBSTANCE: method involves administering diet with high content of nutrient fibers and restricted amount of ordinary hydrocarbons, animal fats and meat broth. Massage is done with manual massage machine Acupress being four-roller bronze or ebonite massage instrument operating along small intestine during 5-6min and then with movements across the abdomen from left to right during 3-4 min. The like movements are done with two-roller bronze or ebonite massage instrument operating along large intestine meridian symmetrically relative to the right and left arm during 4-5 min. All massage movements are done slowly. Procedures are given daily in the morning on empty stomach, before dinner and before going to bed.

EFFECT: enhanced effectiveness in treating chronic constipation cases.

4 dwg

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