The method of treatment of diseases of the vagina and device for its implementation (options)

 

The invention relates to medicine, in particular to the gynecologist, and can be used in the treatment of diseases of the vagina. For this use of sodium chloride in the form of a dry aerosol with a particle size of 0.5 to 20 μm. Sodium chloride is injected into the vagina daily for 10-15 min in the amount of 0.4-4 mg/min 4-5 days using a specially designed speculum. Gynecological mirror in the first embodiment includes an elongated body in the form of interconnected terminals of the rings, the first of which is fixed at the center of the nozzle with means for connection to a source of the working environment, and the second is located at the ends of the rods. The mirror has at least two additional rings installed between the first and second rings, and the source of the working environment. The source operating environment are made in the form of a dispersion chamber from power supply, pump air consumption and air valves. The first valve interconnected with the filter, and the second with means for connection to a source of the working environment. The rods have longitudinal through cavity for delivery of liquid medicines. The second ring is made in the form of the Foundation of the dome-shaped head with a through hole. Second vmeet the possibility of longitudinal displacement. The elongated body is made in the form of an elastic cylinder and has the entire length of the longitudinal troughs with through holes or transverse troughs with through holes. The mirror according to the third variant of execution contains a hollow body in the form of elongated plates. The ends of the plates are interconnected by the ring. The ring has a nozzle. Movable in the longitudinal direction of the pipe is fixed in the center and has a means of connection to the source of the working environment. Extra long plates interconnected with the ring with the possibility of bending, equipped with integral beads and have narrowed to the balls surface. The invention provides a treatment effect due to the rapid decrease in the secretory discharge and prevention of dysbacteriosis and allergic reactions are possible with other methods of treatment. Created versions of devices available for processing the entire surface of the vaginal medicines in the form of aerosols, 4 S. and 7 C.p. f-crystals, 5 Il.

The invention relates to medicine, more specifically to the gynecologist, and may find application in the treatment of diseases of the female genital tract.

Sex the way women are a niche, each segment of which colonizers certain the population is BEGO and local immunity or pH of vaginal contents, exogenous colonization by microorganisms, disruption of microflora in the gut, antibiotic therapy and other changes in the ecosystem of the vagina) can cause disease of the vagina type of non-specific vaginitis bacterial and fungal etiology or vaginosis (dysbacteriosis) and atrophic conditions. Such diseases are often found in the reproductive age (bacterial vaginosis - 24-26% of women, candidiasis - 30-45% and nonspecific vaginitis - 25-30%) and in postmenopausal women (atrophic colpitis in 60-80% of cases). These diseases are accompanied by discharge with odor, itching, discomfort in the vulva and can lead to dyspareunia, inflammation of the upper parts of the genitals (ascending infection) during pregnancy are at risk of interrupting her, chorioamnionitis, infection of the fetus during the passage through the birth canal.

Currently, the treatment of nonspecific vaginitis bacterial and fungal etiology and bacterial vaginosis carry vagina medical suppositories (antibacterial or antifungal) on oily or dry basis, and irrigation vaginal antifungal and/or antimicrobial drugs.

About the cost from sowing flora;

- the rapid development of resistant strains of microorganisms and therefore the need for the appointment of a wide range of medicines, the possibility of allergic reactions to them;

- the possibility of dysbiosis in the use of antibiotics;

- a brief exposition of liquid medicines, and high concentrations of drugs in the initial moment when the use of suppositories that can give irritation at the place of their contact with the vaginal mucosa;

- leakage suppositories and liquid forms of drugs, which creates discomfort.

Closest to the present invention is a method of treatment of nonspecific vaginitis bacterial and fungal etiology of bacterial vaginosis using vaginal suppositories containing antibacterial and antifungal agents such as:

- Klion D 100 (metronidazole 100 mg, clotrimazole 100 mg) 1 tablet in the vagina for 10 days,

- Neo-Penotran (metronidazole 500 mg, miconazole 100 mg) 1-2 candle in the vagina for respectively 14-7 days,

- Interfacially 2% cream clindamycin phosphate on the same dose for 6 days.

This method of treatment recommended E. F. Kira. Bacteria the program has the following disadvantages:

- the duration of treatment (6-10 days);

- leakage of the drug with an oil base (clindamycin), which makes necessary the use of additional spacers, and the violation of the contraceptive effect of condom (erosion latex

- local reactions irritation when using drugs on a dry basis (Klion-D-100),

- allergic reactions;

dysbacteriosis (as used antibacterial agents).

The technical result of the present invention is to reduce the duration of treatment and reduce side effects.

This result is achieved by the fact that as a remedy using sodium chloride in the form of a dry aerosol with a particle size of 0.5 to 20 μm, which is injected into the vagina daily for 10-15 min in the amount of 0.4-4 mg/min for 4-5 days.

An important technique of this method is pre-instrumental smoothing the folds of the vagina and increase its clearance for effective spraying of aerosol particles across the mucosa to increase the area of effect.

We offer the use of sodium chloride in the form of a dry aerosol contributes to settling it in a thin layer on the walls of the vagina, where it is stored, as we have shown,it).

The use of sodium chloride in dry causes, in addition, a rapid decrease in discharge due to the absorption of moisture that already with the first procedure creates comfort.

When using sodium chloride precluded the development of dysbiosis and allergic reactions and irritation of the vagina.

The essence of the method is illustrated by examples.

EXAMPLE 1. Patient K., aged 27, has complained of profuse vaginal discharge with odor within 2 weeks and discomfort during sexual intercourse.

From the anamnesis it is known that the patient had 2 kinds, 1 abortion, chronic oophoritis and bacterial vaginosis with relapse 2 times a year, a dysbacteriosis of an intestine. Living with one sexual partner (contraception - condom).

On examination, the vagina selection milk-white, foamy, with the smell of fish.

During examination: pH discharge more than 4.5, when conducting amine test, the strengthening of the fish smell, smear - leucocytes in norm, discovered the “key” cells in bacterial seeding - coccobacillary flora, samples of urogenital infections by polymerase chain reaction - negative.

According to the anamnesis, inspection and examination diagnosed with bacterial Vinpocetine using the developed device for processing of the vagina, using every day for 10 minutes (2 days), and then 15 min (3 days) was carried out by feeding the vagina dry aerosol of sodium chloride with the size of its particles of 0.5-20 microns in number on the first day 0.4 mg/min, and then gradually from procedure to procedure increased to 2 mg/min according to the patient, the tolerance of procedures good, positive effect (decrease secretions) noted it was already after the first procedure. Normal sex life. Objectively after 5 days of treatment a significant decrease in discharge or odor, amine test is negative, the pH-rate, smear and bacterial seeding rod flora.

In the light of the good curative effect of the treatment was discontinued.

At the reception after 6 months (routine inspection) - no complaints. Objective: to vagina normalizes.

EXAMPLE 2. Patient M., aged 40, has complained of itching in the vulva and rich cheesy discharge from the vagina.

From the anamnesis: the delivery of one, three abortion, uterus, acute endometritis chlamydial etiology treated 2 weeks ago by antibiotics (unidox-Solutab 0,12 times, nystatin 5000004 times in 10 days).

During the inspection: rich wyim diagnosed vulvovaginal candidiasis.

It was decided to carry out treatment using a dry aerosol of sodium chloride analogously to example 1. In one procedure (10-15 min) were feeding from 2 to 4 mg/min of sodium chloride. Portability procedures good, the decrease in discharge observed already after the first treatment, the itching disappeared. After 4 days from the start of treatment: allocation moderate, mucous, smear and bacterial seeding - normalizes.

The patient within one year passes preventive check-up every 3 months for uterine fibroids, with the above no complaints.

To date, the proposed method were treated 40 patients with diagnoses of:

- 16 patients with bacterial vaginosis,

- 12 patients with vaginal candidiasis,

- 9 patients with a combination of bacterial vaginosis and candidiasis,

- 3 patients with non-specific bacterial vaginitis.

The period of observation after treatment for 1 year - no any complaints. The proposed method is compared with the known has a number of advantages.

1) Provides rapid achievement of a positive therapeutic effect (4-5 days), while when using Klion D 100 duration of treatment of 10 days, Neo-Penotran - from 7 to 14 days.

2) the Duration of remission on to the eating of antibiotics is often a dysbacteriosis, requiring extra long special treatment. The method developed at the Department of obstetrics and gynecology, faculty of dentistry University jointly with CJSC “Aeromed” (St. Petersburg) and was clinically tested on the basis of antenatal 26 maternity homes, Moscow with a positive therapeutic effect.

For implementing the inventive method of treatment offered gynecological mirror and its variants.

Presently known devices are, as a rule, for irrigation of the vagina solutions of medicinal substances.

A device for irrigation of the vagina, is described in U.S. patent No. 4061144 (1977). This so-called portable syringe made from environmentally friendly paper in a funnel mounted on the tubular tip having this side extended part (reservoir). The other end of the tip is narrow and ends in a hole (it is introduced into the vagina, through the axial passage).

It is known device, namely vaginal spray (U.S. patent No. 4167186, 1979), made in the form of a reservoir tip, form of a hollow tube, 1/2 of which is conical and formed opening (at the tank), the second half of the tube to which the edges”, where there are openings.

All the above devices are, as already mentioned, for irrigation of the vagina with liquid medicines and unsuitable for the purposes of the present invention.

Closest to the first two variants of the present invention is gynecological mirror containing an elongated housing in the form of interconnected terminals of the rings, the first of which is fixed at the center of the nozzle with means for connection to a source of the working environment, and the second is located at the ends of the rods (see catalog And/Schwab, Moscow, 1901, S. 605, No. 10116).

Closest to the third variant of the present invention is used as a gynecological mirror device containing an elongated housing in the form of plates, interconnected by a ring having a fixed center pipe with means for connection to a source of the working environment (see above directory, S. 617, No. 10416).

The disadvantages of these devices are adapted for use with such a source the working environment, as the camera dispersion.

The technical result of the present invention is to create variants of the device, suitable for processing all p what erom version of its execution gynecological mirror, containing an elongated housing in the form of interconnected terminals of the rings, the first of which is fixed at the center of the nozzle with means for connection to a source of the working environment, and the second is located at the ends of the rods, in contrast to the nearest analogue contains at least two additional rings installed between the first and second rings, and the source of the working environment, made in the form of a dispersion chamber from power supply, pump air consumption and air valves, the first of which is interconnected with the filter, and the second with means for connection to a source of the working environment, when the rods have longitudinal through cavity for flow of the liquid drug and the second ring is made in the form of the base of the dome-shaped head with the hole.

In some cases, its performance or use of gynecological mirror can have the camera dispersion made in the form of device for grinding salt, and the pump flow may be a mechanical actuator, or an electric actuator or manual drive, the device for grinding salt may be in the form of a mill, and the pump flow in the form of a fan, or the pumping device, or membrane pump device, or in the form of microphone, or in the form of a microcompressor.

In the second embodiment, the gynecological mirror containing an elongated body with a fixed center pipe having means connected to a source of the working environment, in contrast to the closest analogue is the pipe, which is connected with the elongated body through the ring and has the possibility of longitudinal movement, with its elongated body is made in the form of an elastic cylinder and has the entire length of the longitudinal gutters with through holes or transverse gutters with through holes, and the source operating environment are made in the form of a dispersion chamber from power supply, pump air consumption and air valves, the first of which is interconnected with the filter, and the second tool connected to a source of the working environment.

In some cases, of its execution or use the second option speculum may also contain a camera dispersion made in the form of device for grinding salt, and booster air flow, which has a mechanical actuator or electric actuator or manual actuator, a device for smallarea of compressed air and a shut-off valve or in the form of elastic, for example, rubber containers, or pumping device, or membrane pump device, or in the form of microphone, or in the form of a microcompressor. In addition, longitudinal gutters can be made spiral or transverse gutters can be made wavy.

In the third variant of its execution gynecological mirror, containing a hollow body in the form of elongated plates, interconnected by a ring having a fixed center pipe with means for connection to a source of a working environment that differs from the closest analogue to the fact that its elongated plate interconnected with the ring with the possibility of bending, equipped with integral beads and have narrowed to the ball surface, and the nozzle has a possibility of longitudinal displacement, and the source operating environment are made in the form of a dispersion chamber from power supply, pump air consumption and air valves, the first of which is interconnected with the filter, and the second tool connected to a source of the working environment.

In some cases, of its execution or use of the third option speculum may contain, as the two previous options, the camera dispel anceschi drive, engine or electric motor or manual drive, the device for grinding salt may be in the form of a mill, and the pump flow in the form of a fan, or in the form of compressed air and shut-off valve, or in the form of elastic, for example, rubber containers, or pumping device, or membrane pump device, or in the form of microphone, or in the form of a microcompressor.

In Fig.1 shows a diagram of a speculum, where 1 is the camera dispersion, 2 - output hole of her 3 - booster air flow, 4 - power supply 5 - air filter, 6 - outlet, 7 - ring, 8 - rods, 9 - domed head. In Fig.2-5 presents embodiments of the speculum.

The mirror works as follows. In the camera dispersion 1 is loaded sodium chloride, due to the rotation of the activators grinding powder and mixing it with air (gas) coming from the pump air flow 3. Through the outlet 2 and the pipe 6, the aerosol enters the vagina, the presence of rings 7 passing through them by the rods 8 can push all the folds of the vagina, providing good access and settling of aerosol on all the walls here are more effective treatment of posterior wall of vagina. If necessary, prior or subsequent irrigation of the vagina with liquid medicine is supplied through the fitting in the hollow tubes to the rear, then washing all the vagina. Due to the hygroscopicity of the particles of sodium chloride grinding it just before the introduction into the vagina excludes the formation of a dense mass or large crystals, and prevents sticking of particles due to agglomeration.

Two further variants of the speculum is the same as his first option and also provides the best possible treatment of the whole surface of the walls of the vagina.

In more detail, you can focus on the work of its third variant, which is shown in Fig.5.

Flexible mounting plates to the ring provides the ability to make them different positions: closed with the introduction of the device into the vagina and unveiled inside it. The open position of the plates, which is their natural state, contributes to the smoothing of the inner folds of the vagina and with the passage of salt spray provides effective treatment throughout its surface. When removing the speculum from the vagina petals again smigo mucosa.

Claims

1. The method of treatment of diseases of the vagina through medical means, characterized in that as a therapeutic agent use of sodium chloride in the form of a dry aerosol with a particle size of 0.5 to 20 μm, which is injected into the vagina using a speculum daily in the amount of 0.4-4 mg/min for 10-15 minutes for 4-5 days.

2. Gynecological mirror containing an elongated housing in the form of interconnected terminals of the rings, the first of which is fixed at the center of the nozzle with means for connection to a source of the working environment, and the second is located at the ends of the rods, characterized in that it has at least two additional rings installed between the first and second rings, and the source of the working environment, made in the form of a dispersion chamber from power supply, pump air consumption and air valves, the first of which is interconnected with the filter, and the second with means for connection to a source of the working environment, when the rods have longitudinal through cavity for flow of the liquid drug and the second ring is made in the form of the base of the dome-shaped head with the hole.

3. Mirror on p. 2, eachoda air has a mechanical actuator, engine or electric motor or manual drive.

4. Mirror on p. 3, characterized in that the device for grinding salt is made in the form of a mill, and the pump flow is executed in the form of a fan, or in the form of compressed air and shut-off valve, or in the form of elastic, such as rubber, capacity, or pumping device, or membrane pump device, or in the form of microphone, or in the form of a microcompressor.

5. Gynecological mirror containing an elongated body with a fixed center pipe having means connected to a source of working medium, characterized in that the pipe connected to the elongated body through the ring and has the possibility of longitudinal movement, and the elongated body is made in the form of an elastic cylinder and has the entire length of the longitudinal gutters with through holes or transverse gutters with through holes, and the source operating environment are made in the form of a dispersion chamber from power supply, pump air consumption and air valves, the first of which is interconnected with the filter, and the second with means for connection to a source of the working environment.

6. Mirror on p. 5, characterized in that the camera dispergirovany the electric actuator, or manual drive.

7. Mirror on p. 6, characterized in that the device for grinding salt is made in the form of a mill, and the pump flow is executed in the form of a fan, or in the form of compressed air and shut-off valve, or in the form of elastic, such as rubber, capacity, or pumping device, or membrane pump device, or in the form of microphone, or in the form of a microprocessor.

8. The mirror on the PP.5-7, characterized in that the longitudinal gutters made spiral or transverse gutters made wavy.

9. Gynecological mirror, containing a hollow body in the form of elongated plates, interconnected by a ring having a fixed center pipe with means for connection to a source of working medium, characterized in that the elongated plate interconnected with the ring with the possibility of bending, equipped with integral beads and have narrowed to the ball surface, and the nozzle has a possibility of longitudinal displacement, and the source operating environment are made in the form of a dispersion chamber from power supply, pump air consumption and air valves, the first of which is interconnected with the filter, and the second with means for connection to the East the STS to grind salt, and the winner of the air flow has a mechanical actuator or electric actuator or manual drive.

11. Mirror on p. 10, characterized in that the device for grinding salt is made in the form of a mill, and the pump flow is executed in the form of a fan, or in the form of compressed air and shut-off valve, or in the form of elastic, such as rubber, capacity, or pumping device, or membrane pump device, or in the form of microphone, or in the form of a microcompressor.