Derivatives of indole, drug, containing the retrieval method (variants)
The invention relates to inhibitors tyrosinekinase type bis-indolylmaleimide compounds of the formula I


Claims
1. Derivatives of indole of General formula













Same patents:
The invention relates to derivatives of benzimidazole and their use in therapy, in particular for the treatment or prophylaxis of viral infections such as caused by herpes viruses
The invention relates to 3'-substituted derivative of a nucleoside represented by the General formula (1), where B is a base of the nucleic acid, which may have a Deputy, Z represents a lower alkylamino or lower alkenylphenol group which may be substituted by a group represented by the General formula (2), in which Ra, Rband Rcthe same and are lower alkyl or phenyl group, R1and R2individually represent a hydrogen atom or a benzoyl and R3represents a hydrogen atom, a residue of a mono - or polyphosphoric acid, or benzoic acid, provided that the sugar component is ribose, or its pharmaceutically acceptable salt
The invention relates to the derivatives of introperative General formula
< / BR>in which R1and R2each independently H, lower alkyl, lower alkenyl, phenyl, phenylalkyl, pyridyl or imidazolyl, and each of the groups lower alkyl, lower alkenyl, phenyl, phenylalkyl is optional from 1 to 5 substituents selected from carboxy, carbamoyl, cyano and hydroxy-group; or the group-Y - R2where Y is a carbonyl, thiocarbonyl or sulfonyl, and R3- H, lower alkyl, trifluoromethyl, phenyl, lower alkoxy, hydrazino, amino, phenylamino, carbarnoyl or Peregrina group, the lower alkyl or phenyl group are optionally 1 to 4 substituents such as hydroxy-group adjacent to the hydroxy-group-protected alkalinous group, carboxy or cyano, or R1and R2taken together with the nitrogen atom to which they are attached, form a piperazinilnom or pyrrolidinyloxy the group may hydroxylamino lower alkyl group, G - pentasa or hexana group, X1and X2independently H or halogen, OH, lower alkoxy - or benzyloxy

The way to obtain the pyridine nucleosides // 2036199
The invention relates to pyrimidine nucleosides used in medicine, in particular for the treatment and prevention of viral diseases herpes
The invention relates to the chemistry of biologically active compounds, and specifically to an improved process for the preparation of a derivative of hematoporphyrin, which is used as a photosensitizer for photodynamic therapy (PDT) of malignant tumors
The invention relates to a hydrazides in a series of bacteriochlorophyll and General formula I, where R1=COCH3CH(OH)CH3CH=CH2; R2=H,CH3C2H5; R3and R4=H, CH3, Tos, and the method of obtaining hydrazides I by reacting derivatives of bacteriochlorophyll and with additional anhydrous cycle with hydrazinehydrate and subsequent cyclization of the resulting intermediate hydrazide by adding to the reaction mass of hydrochloric acid; the proposed hydrazides have high photoinduced activity; in the absence of light irradiation hydrazides I at concentrations 6-15 times phototoxic not affect the growth of the cell culture
Underrattelsetjansten phthalocyanine cobalt // 2210572
Underrattelsetjansten phthalodinitrile // 2206563
The invention relates to novel disubstituted phthalodinitrile, which can be used as intermediate products in the synthesis of new octasubstituted of metallophthalocyanines used as dyes, liquid-crystalline compounds, catalysts of different processes, one-dimensional conductors, materials sensitive elements of sensors gases, photosensitive materials for siteregistered devices
The invention relates to organic chemistry, specifically to a method for 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo-[5,5,0,03,11that 05,9] dodecane used as high-performance explosives
The invention relates to the field of medicine and for the use of OCTA-4,5-carboxyfullerenes aluminum or zinc formula
< / BR>where M= AlOH, Zn, as photosensitizers for photodynamic therapy

The invention relates to a new method of obtaining metallizovannyh derived bacteriochlorophyll for use in the methods of photodynamic therapy (PDT) and in vivo diagnostics and photodynamic destruction of viruses and microorganisms in vitro, as well as some new metallosalen derived bacteriochlorophyll
,,
,
-tetramethylcyclotetrasiloxane and methods for their production" target="_blank">
The invention relates to chemistry and chemical technology, and more specifically to the synthesis of a new breed of macroheterocyclic compounds, tetrasauropus chlorine, namely
,
,
,
-tetramethylcyclotetrasiloxane






A method of obtaining a condensed polycyclic alkaloids, compounds, method of inducing apoptosis // 2215737
The invention relates to a method for producing a condensed polycyclic alkaloids of General formula I, including new, including phase cyclization of azometynoylid General formula II, where a is optionally substituted aryl, Z is oxygen, n = 1, Y is optionally substituted aryl, W and X together with the nitrogen atoms and the carbon to which they are attached, form a saturated or unsaturated nitrogen-containing heterocyclic group, possibly substituted and possibly condensed with aryl, carbocyclic or heterocyclic group
The invention relates to novel condensed pyrrolo (2,3-C)carbazole-6-Onam represented by the General formulas (I) and (II)
The invention relates to polypeptide to the compound of General formula I, where R1indicates the lowest alkanoyl, substituted unsaturated 6-membered heterophilically group containing at least one nitrogen atom which may have one or more suitable substituents; lower alkanoyl, substituted 1,2,3,4-tetrahydroisoquinoline, which may have one or more suitable substituents; lower alkanoyl, substituted unsaturated condensed heterocyclic group containing at least one oxygen atom, which may have one or more suitable substituents, or pharmaceutically acceptable salts
The invention relates to new compounds include,
-,
or
-cyclodextrin or its alkyl - or hydroxyalkylated and (6R)-, (6S) - or (6R,S)-5,10 - methylenetetrahydrofolic acid or its salts, stable solutions of compounds include cyclodextrin, a method of stabilizing aqueous solutions and the way to obtain stable solutions, which can be used in the pharmaceutical industry


