A way to improve the condition of the endometrium
(57) Abstract:The invention relates to medicine and is intended to improve the condition of the endometrium. Abdominal-vaginally with 5-7 days of the menstrual cycle affect packs bipolar asymmetric pulses with alternating periods of excitation in 6 and relaxation in 2, with pulse repetition rate of 10 Hz, with ischemia and increased rates of 20% from the specified value. The method allows improves the condition of the endometrium. The invention relates to medicine, in particular to the gynecologist, and may find application in the restoration of reproductive function of women.There is a method of improving the condition of the endometrium to restore reproductive function of women, in particular, to prepare for implantation in IVF OD using cyclic hormone [in Vitro fertilization and new directions in the treatment of female and male infertility (theoretical and practical approaches).: A guide for physicians / edited by C. I. Kulakova, B. C. Leonova, M.: Medical information Agency, 2001 - 261 S.].He has certain disadvantages: the possibility of side effects that can impair quality of life PAC is on hemostasis, the function of the liver, the cardiovascular system; the development of allergic reactions.The objective of the invention is a method for improving the state of the endometrium and increase the likelihood of pregnancy, including after IVF and PE and reduce the risk of abortion.This object is achieved by the use of packs asymmetric bipolar pulse both positively and negatively inverted, which are exposed to alternating periods of excitation (6) and relaxation (2), with a frequency of 10 Hz, with ischemia and increased rates of 20% from the specified value, abdominal-vaginally. The intensity ranges from 0 to 100 mA with regard to the individual reactions of the patient.Practically the method is as follows.Treatment starts on the 5-7th day of the menstrual cycle and conduct daily for 10-15 days. Use domestic hardware-software complex "Andro-Gin", intracavitary and plate electrodes of this device.Treatment method.Position of patient: lying on back, legs bent at the knee joints and divorced. Intracavitary electrode is introduced into the posterior fornix of the vagina is p - "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course is 10-15 procedures.The following examples illustrate the proposed method.Example 1/ Patient K., aged 32, outpatient map 12614/1. History: viral hepatitis in 10 years, a violation of fat metabolism 20 years. Gynecological diseases: cervical erosion, diathermocoagulation in 1995; in 1997, the course of inseminate sperm donor without effect; in 1998, conducted IVF attempt and PE without effect. Clinical diagnosis: pelvic peritoneal adhesions. Chronic endometritis. Infertility 1 (male factor). In may 2001, made hysteroscopy, diagnostic curettage of the uterine cavity. When hysteroscopy - mucous uneven thickness, unevenly dyed, vascular pattern is expressed. According to the histological examination of scraping of the endometrium is a chronic endometritis. According to the U.S. from September 21, 2001. (on day 23 of the menstrual cycle the endometrium of heterogeneous structure, thickness 0.8 cmOn the 7th day menstrual lying on his back, legs bent at the knee joints and divorced. Intracavitary electrode was inserted in the posterior vaginal vault. The plate electrode had contact in the suprapubic area. Impact - "stimulation"; choice "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude was determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course was 10 procedures.Directly after a course of physiotherapy noted the approximation determined by palpation of the uterus to the physiological increase the excursion of the uterus, the softening of the adhesive structures. In December 2001 (2 months after completion of the course CFT) on the 23rd day of the cycle, according to the ultrasound endometrium uniform thickness (1.1 cm) and ecoprotect. After IVF and embryo transfer occurred uterine pregnancy, which to date is 29-30 weeks.Example 2. Patient T., 35, outpatient map 1367/01.History: chickenpox, measles. Gynecological diseases: chronic bilateral salpingo-oophoritis, chronic endometritis, adhesions in the pelvis, Trubin.g. conducted two operative laparoscopy in order to restore patency of the fallopian tubes, three hysteroscopy with histological examination of scraping of the endometrium (histologically - chronic endometritis in 1997 and slimy body of the uterus stage of secretion in 2001) and 18 IVF attempts and PE without the effect of pregnancy, except for one biochemical pregnancy. According to the U.S. from November 10, 2001 at 22 day cycle endometrial thickness 1.0 cm, homogeneous structure.On the 7th day of the menstrual cycle started electropulse therapy. Used APK Andro-Gin". Treatment method: position the patient lying on his back, legs bent at the knee joints and divorced. Intracavitary electrode was inserted in the posterior vaginal vault. The plate electrode had contact in the suprapubic area. Impact - "stimulation"; choice "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude was determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course was 10 procedures.Directly after a course of physiotherapy celebrated approximation by palpation is R. In January 2002 (1 month after completion of the course CFT) on the 23rd day of the cycle according to the ultrasound endometrium, uniform thickness (1.3 cm) and ecoprotect. After IVF and embryo transfer occurred uterine pregnancy (twins), which to date is 16-17 weeks.Example 3. Patient K., aged 34, outpatient map 17210/1.Moved and comorbidities: right nephroptosis, dolichosigmoid, chronic pyelonephritis with 7 years, the last exacerbation in 1999 (inpatient treatment), 1999 dystonia in cardiac type. Gynecological anamnesis - 4 pregnancy: timely delivery in 1993 ; artifactual abortion in 1989 and 1994 without complications; in 1999, the scraping of the walls of the uterus on the occasion of missed abortion, complicated by endometritis (inpatient treatment). Since that time, concerned about light perimenstrually allocation and rich, painful menstruation. In 2001, conducted diagnostic curettage with histological examination of scraping of the endometrium (Geest. 8767: ferro-fibrous polyp of endometrium, the mucous membrane of the womb is defective stage secretion), after which these complaints were preserved. According to the ultrasound on the 7th day of the cycle identified assume is initiated electro-therapy. Used APK Andro-Gin". Treatment method: position the patient lying on his back, legs bent at the knee joints and divorced. Intracavitary electrode was inserted in the posterior vaginal vault. The plate electrode had contact in the suprapubic area. Impact - "stimulation"; choice "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude was determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course was 10 procedures.Directly after a course of physiotherapy noted the approximation determined by palpation of the uterus to the physiological increase the excursion of the uterus, the softening of the adhesive structures. Two subsequent menstrual period were less abundant and painful, perimenstrually allocation has decreased significantly. In January 2002 (2 months after completion of the course CFT) on the 7th day of the cycle according to the ultrasound endometrium, uniform thickness (0.4 cm) and ecoprotect.With the aim of improving the condition of the endometrium, we performed electrotherapy 22 women. 18 of them complained of light perimenstrually allocation, the average duration of menstrual blood loss decreased by 1.4 days due to light perimenstrually discharge; according to ultrasound in the dynamics marked the approach of the echographic picture of the endometrium to the physiological in 7 patients, which the study was conducted in the same days of the cycle with an interval of 2 months; 3 patients after IVF and embryo transfer pregnancy. A way to improve the condition of the endometrium, characterized in that the abdominal-vaginally with 5-7 days of the menstrual cycle affect packs bipolar asymmetric pulses with alternating periods of excitation in 6 and relaxation in 2, with pulse repetition rate of 10 Hz, with ischemia and increased rates of 20% from the specified value.
SUBSTANCE: through puncture opening in proximal and distal directions one should perform osseous tunnels being coaxial to osseous log to connect, thus, the cavity of osseous cyst with medullary canal. Through the parts of healthy bone at the distance of 1-2 cm against cyst's edge in oblique direction one should implant rigid electrodes at the angle of 45 deg. against its center by applying beck's needles with dielectric covering. Subcutaneously one should implant elastic electrodes in projection of lesion focus and connect an electrostimulating unit to cutaneous ends of electrodes. Onto intraosseous electrodes one should supply impulse current of negative polarity, and onto elastic ones - of positive polarity at 10-20 mcA power and frequency of 0.5 Hz, of total duration and front of rectangular impulses cut being 200 mcsec, not more.. One should affect with impulse electric currents on the 24-h basis till complete covering the osseous defect observed.
EFFECT: higher efficiency of therapy.
FIELD: medicine; cosmetics.
SUBSTANCE: method involves preparing and applying electrically activated cosmetic therapy substance. Preparation process involves passing alternating electric current through electrolyte material. The alternating current is applied for at least 10 min with preferential time being 4-8 h long for changing physical properties of the substance. Then the current is switched off. The active substance is administered as inhalation in pulmonary tract or as injections into human or animal body. The substance properties are retained for some limited time.
EFFECT: enhanced effectiveness of treatment; excluded electric current passage through patient tissues; excluded drug concentration in the vicinity of electrodes.
50 cl, 13 dwg
SUBSTANCE: method involves concurrently acting with stimulating electric pulses and back pressure pulses upon the prostate from the large intestine side synchronized with the stimulating electric pulses under excessive rinsing solution pressure into posterior urethra region. Device has pneumatic massage unit as elastic shell enveloping hollow cylindrical casing having a row of radial holes for supplying compressed air into the shell and periodic pulsating pressure source having at least one unit for producing electric pulses and pneumo-electromagnetic valve which electromagnet anchor is connected to electric pulse production unit outputs. Unit for electrically stimulating perineal muscles and prostate having stimulating catheter electrode and reservoir containing rinsing solution attached to catheter electrode are available in the device. Electric stimulation unit output is connected to input of unit for producing pressure pulses. Periodic pulsating pressure source is manufactured as elastic pneumatic chamber brought in continuous mechanical engagement with electromagnet anchor of the pneumo-electromagnetic valve and tightly joined via tube, cylindrical tube cavity and radial holes therein to the elastic shell of the massage member.
EFFECT: enhanced effectiveness of treatment; accelerated treatment course.
3 cl, 10 dwg
SUBSTANCE: method involves carrying out endoscopic operation. SCENAR-therapy is additionally administered with pulsating bipolar electric current being used without constant component as pulses at succession frequency from 10 to 350 Hz including swinging frequency mode within 30-120 Hz bandwidth with 2 to 8 pulses formed as batches at succession rate of 540 Hz to 4.5 kHz. The signal is modulated by varying ratio of action time to pauze duration within 1:1-1:5. 1-3 SCENAR-therapy courses are administered with 1-3 months long pauses. The first course begins at the first menstrual cycle occurred after endoscopic operation. Each course is carried out according to a scheme. 15-20 sessions are administered during the first menstrual cycle and 7-10 sessions are administered during the second menstrual cycle. The 25-40 min long sessions are applied daily.
EFFECT: enhanced effectiveness of treatment.
SUBSTANCE: method involves concurrently acting upon patient auditory system with acoustic signal produced by a musical composition selected on basis of patient health state and electric signals of the same musical composition acting upon patient skin. The electric signals amplitude-modulated with depth of 15-85%, act upon the patient via adhesive skin electrodes during 15-40 min. Hearing-add device is subjected to acoustic signals amplitude-modulated with depth of 15% and higher. Amplitude-modulation frequency is selected within the limits of 1.2-9.8 Hz. Modulation is carried out with frequency corresponding to patient disease frequency and action power is chosen on basis of subjective patient sensations. Device has unit for performing musical composition, the first and the second power amplifier, matching unit, adhesive electrodes and electroacoustic converter as well as electrostimulation modulator, acoustic modulator, the first and the second modulation depth regulator, the first and the second power control unit. Musical signal reproduction output unit is connected to the first inputs of electrostimulation modulator and acoustic modulator, which second inputs are connected to input of introduced controllable modulation frequency oscillator and modulation depth regulators are connected to their third inputs. Electrostimulation modulator output is connected to adhesive electrodes via the first power amplifier and matching unit. Sound modulator is connected to the electroacoustic converter via the second power amplifier. The first and the second power regulator are connected to the second inputs of the first and the second power amplifier. Unit for recording sessions is additionally introduced for replicating therapeutic sessions, its first input being connected to the electrostimulation modulator and the second one to the sound modulator output.
EFFECT: enhanced effectiveness of treatment.
4 cl, 1 dwg
SUBSTANCE: method involves specifying disease stage, determining suggestibility degree, programming on abstinence from alcohol consumption for a 6-12 months long period the patient determines on the own free will. Treatment is administered with bipolar electric asymmetric current pulses of 3-5 mA being applied on the background of relaxing melody later on in reanimation room. Assurance in overcoming difficulties of life and becoming free of alcohol addiction is suggested on this background. Placebo is concurrently intravenously administered as drop infusion imitating coding preparation as alcohol receptor blocker. Suggestive accentuation is concentrated on possible complications caused by alcohol consumption after introducing the preparation. The aversion against alcohol is invoked by making drop infusion of medicament mixture causing fever sensation and myorelaxation. The patient swallows 2-3 gulps of alcohol and the provoked responses are associated to them with a cause-effect relation like alcohol-bad health state and fixed with intramuscular placebo injection simulating oil code preparation.
EFFECT: enhanced effectiveness of treatment; prolonged remission period.
FIELD: medicine, neurosurgery.
SUBSTANCE: the present innovation deals with surgical treatment of neurological complications in patients with degenerative-dystrophic vertebral lesion and partial disorder of conductor-segmental spinal functions. One should surgically remove spinal compression due to resecting anterior departments of affected osseous-cartilaginous structures of vertebral-motor segment. One should apply electrodes: one pair - intraoperationally epidurally upon dura mater above anterior spinal departments being above the level of its lesion; then another pair of electrodes - by puncturing into area of posterior departments being below the level of its lesion to conduct electrostimulation. Moreover, therapy should be supplemented with phonophoresis with neuroprotector preparations. Electrostimulation of posterior spinal departments starts on the 2nd d, and that of anterior departments - on the 3d or 4th d after operation. Parameters of curative electrostimulation should be matches for every patient individually with the help of electroneuromyography. The innovation enables to decrease postoperative complications.
EFFECT: higher efficiency of therapy.
2 cl,1 ex
FIELD: medicine, traumatology, neurosurgery, microsurgery, neurotraumatology.
SUBSTANCE: one should fulfill autoneuroplasty of nervous defect, implantation of wire electrodes epineurally for both ends of contact areas of nerve's affected part at arranging insulation-free electrodes with their opened active ends along the direction of affected nerve. Moreover, before implantation of wire electrodes one should divide their ends into fibers to obtain filamentous wires and embrace nerve trunk and autoneurotransplant along their circumference. Electrodes should be placed at distal and proximal ends of affected nerve being about 5-10 mm above and below neurorhaphy area to perform electrostimulation. The method enables to accelerate regeneration of nervous fiber and decrease lesions of nervous tissue.
EFFECT: higher efficiency of therapy.
1 cl, 5 dwg, 1 ex
FIELD: medicine, physiotherapy.
SUBSTANCE: at the first stage, one should affect with magnetic field upon vertebral reflexogenic areas - volar surfaces - located at colored plates as straps. At the second stage, one should affect with magnetic field upon the area of vertebral column that helps to improve psychoemotional state in patients.
EFFECT: higher efficiency of therapy.
2 cl, 1 ex
FIELD: medicine, neurology, psychiatry.
SUBSTANCE: one should affect with amplipulsephoresis of "Berlition" preparation in rectified mode. One should apply types III and V of operations at modulation frequency being 130-150 Hz, modulation depth of 50-75%, impact duration for every type of operation lasts for 5-7 min. During the 1st d electrode-cathode should be located in inferior cervical - superior thoracic department of vertebral column, and electrode-anode - at anterior and posterior surfaces of forearms. During the 2nd d - in inferior thoracic - superior lumbar department of vertebral column and at anterior-lateral and posterior surfaces of shins, correspondingly. The present method improves clinico-electrophysiological and biochemical parameters.
EFFECT: higher efficiency of therapy.
5 ex, 8 tbl