A way to improve the condition of the endometrium

 

(57) Abstract:

The invention relates to medicine and is intended to improve the condition of the endometrium. Abdominal-vaginally with 5-7 days of the menstrual cycle affect packs bipolar asymmetric pulses with alternating periods of excitation in 6 and relaxation in 2, with pulse repetition rate of 10 Hz, with ischemia and increased rates of 20% from the specified value. The method allows improves the condition of the endometrium.

The invention relates to medicine, in particular to the gynecologist, and may find application in the restoration of reproductive function of women.

There is a method of improving the condition of the endometrium to restore reproductive function of women, in particular, to prepare for implantation in IVF OD using cyclic hormone [in Vitro fertilization and new directions in the treatment of female and male infertility (theoretical and practical approaches).: A guide for physicians / edited by C. I. Kulakova, B. C. Leonova, M.: Medical information Agency, 2001 - 261 S.].

He has certain disadvantages: the possibility of side effects that can impair quality of life PAC is on hemostasis, the function of the liver, the cardiovascular system; the development of allergic reactions.

The objective of the invention is a method for improving the state of the endometrium and increase the likelihood of pregnancy, including after IVF and PE and reduce the risk of abortion.

This object is achieved by the use of packs asymmetric bipolar pulse both positively and negatively inverted, which are exposed to alternating periods of excitation (6) and relaxation (2), with a frequency of 10 Hz, with ischemia and increased rates of 20% from the specified value, abdominal-vaginally. The intensity ranges from 0 to 100 mA with regard to the individual reactions of the patient.

Practically the method is as follows.

Treatment starts on the 5-7th day of the menstrual cycle and conduct daily for 10-15 days. Use domestic hardware-software complex "Andro-Gin", intracavitary and plate electrodes of this device.

Treatment method.

Position of patient: lying on back, legs bent at the knee joints and divorced. Intracavitary electrode is introduced into the posterior fornix of the vagina is p - "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course is 10-15 procedures.

The following examples illustrate the proposed method.

Example 1/ Patient K., aged 32, outpatient map 12614/1. History: viral hepatitis in 10 years, a violation of fat metabolism 20 years. Gynecological diseases: cervical erosion, diathermocoagulation in 1995; in 1997, the course of inseminate sperm donor without effect; in 1998, conducted IVF attempt and PE without effect. Clinical diagnosis: pelvic peritoneal adhesions. Chronic endometritis. Infertility 1 (male factor). In may 2001, made hysteroscopy, diagnostic curettage of the uterine cavity. When hysteroscopy - mucous uneven thickness, unevenly dyed, vascular pattern is expressed. According to the histological examination of scraping of the endometrium is a chronic endometritis. According to the U.S. from September 21, 2001. (on day 23 of the menstrual cycle the endometrium of heterogeneous structure, thickness 0.8 cm

On the 7th day menstrual lying on his back, legs bent at the knee joints and divorced. Intracavitary electrode was inserted in the posterior vaginal vault. The plate electrode had contact in the suprapubic area. Impact - "stimulation"; choice "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude was determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course was 10 procedures.

Directly after a course of physiotherapy noted the approximation determined by palpation of the uterus to the physiological increase the excursion of the uterus, the softening of the adhesive structures. In December 2001 (2 months after completion of the course CFT) on the 23rd day of the cycle, according to the ultrasound endometrium uniform thickness (1.1 cm) and ecoprotect. After IVF and embryo transfer occurred uterine pregnancy, which to date is 29-30 weeks.

Example 2. Patient T., 35, outpatient map 1367/01.

History: chickenpox, measles. Gynecological diseases: chronic bilateral salpingo-oophoritis, chronic endometritis, adhesions in the pelvis, Trubin.g. conducted two operative laparoscopy in order to restore patency of the fallopian tubes, three hysteroscopy with histological examination of scraping of the endometrium (histologically - chronic endometritis in 1997 and slimy body of the uterus stage of secretion in 2001) and 18 IVF attempts and PE without the effect of pregnancy, except for one biochemical pregnancy. According to the U.S. from November 10, 2001 at 22 day cycle endometrial thickness 1.0 cm, homogeneous structure.

On the 7th day of the menstrual cycle started electropulse therapy. Used APK Andro-Gin". Treatment method: position the patient lying on his back, legs bent at the knee joints and divorced. Intracavitary electrode was inserted in the posterior vaginal vault. The plate electrode had contact in the suprapubic area. Impact - "stimulation"; choice "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude was determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course was 10 procedures.

Directly after a course of physiotherapy celebrated approximation by palpation is R. In January 2002 (1 month after completion of the course CFT) on the 23rd day of the cycle according to the ultrasound endometrium, uniform thickness (1.3 cm) and ecoprotect. After IVF and embryo transfer occurred uterine pregnancy (twins), which to date is 16-17 weeks.

Example 3. Patient K., aged 34, outpatient map 17210/1.

Moved and comorbidities: right nephroptosis, dolichosigmoid, chronic pyelonephritis with 7 years, the last exacerbation in 1999 (inpatient treatment), 1999 dystonia in cardiac type. Gynecological anamnesis - 4 pregnancy: timely delivery in 1993 ; artifactual abortion in 1989 and 1994 without complications; in 1999, the scraping of the walls of the uterus on the occasion of missed abortion, complicated by endometritis (inpatient treatment). Since that time, concerned about light perimenstrually allocation and rich, painful menstruation. In 2001, conducted diagnostic curettage with histological examination of scraping of the endometrium (Geest. 8767: ferro-fibrous polyp of endometrium, the mucous membrane of the womb is defective stage secretion), after which these complaints were preserved. According to the ultrasound on the 7th day of the cycle identified assume is initiated electro-therapy. Used APK Andro-Gin". Treatment method: position the patient lying on his back, legs bent at the knee joints and divorced. Intracavitary electrode was inserted in the posterior vaginal vault. The plate electrode had contact in the suprapubic area. Impact - "stimulation"; choice "intraoral"; polarity - positive and negative (10 min); mode 3; frequency 10 Hz deviation 20%; excitation 6; pause 2 C. Indicators individually desired amplitude was determined by the sensations of the patient. The total duration of the procedure 20 minutes Daily. The course was 10 procedures.

Directly after a course of physiotherapy noted the approximation determined by palpation of the uterus to the physiological increase the excursion of the uterus, the softening of the adhesive structures. Two subsequent menstrual period were less abundant and painful, perimenstrually allocation has decreased significantly. In January 2002 (2 months after completion of the course CFT) on the 7th day of the cycle according to the ultrasound endometrium, uniform thickness (0.4 cm) and ecoprotect.

With the aim of improving the condition of the endometrium, we performed electrotherapy 22 women. 18 of them complained of light perimenstrually allocation, the average duration of menstrual blood loss decreased by 1.4 days due to light perimenstrually discharge; according to ultrasound in the dynamics marked the approach of the echographic picture of the endometrium to the physiological in 7 patients, which the study was conducted in the same days of the cycle with an interval of 2 months; 3 patients after IVF and embryo transfer pregnancy.

A way to improve the condition of the endometrium, characterized in that the abdominal-vaginally with 5-7 days of the menstrual cycle affect packs bipolar asymmetric pulses with alternating periods of excitation in 6 and relaxation in 2, with pulse repetition rate of 10 Hz, with ischemia and increased rates of 20% from the specified value.

 

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