The method of treatment of purulent wounds

 

(57) Abstract:

The invention relates to medicine, namely to surgery, and can be used for the treatment of purulent wounds. Spend ozonation environment and wounds. After that, the wound is treated with a mixture prepared ex tempore of ozonated water and solution powergel. Then put a bandage impregnated with the same mixture. Ozonated water is obtained by passing an ozone-oxygen mixture at a concentration of 200 g/L. Concentration of powergra in a solution of 0.1-0.3%. The method allows to reduce the spread of hospital infections.

The invention relates to medicine, namely to surgery and traumatology, and is intended for the treatment and prevention of suppurative complications of wounds.

There is a method of treatment of postoperative wounds using ozonated aqueous solutions with ozone concentration of 4 mg/l (Vasina T. A., Sidorov, I. C., hares C. J. et al. The results of the application of ozonized solutions in the clinic //Ozone in biology and medicine: abstracts. Dokl. - N.-Novgorod, 1992. - S. 40-41).

However, the proposed method is not very effective at high contamination of postoperative wounds conditionally pathogenic microflora, as for full inactivates, and at the same time manifests toxic effects of ozone.

Also known is a method of treatment of purulent wounds (RF patent 2142279; IPC And 61 To 33/38, And 61 N 7/00, publ. 10.12.99; BI 34) by washing with a solution of silver-containing antiseptic - powergel at low concentrations (0.1% to 0.3%) treated with ultrasound.

However, despite the high bactericidal activity used antiseptics, during sonication the risk of contamination of the air dressing microbes from the wound still remains, and sanitation of premises requires additional cost and time.

Closest to the claimed method is the prevention of septic complications in trauma hospitals, consisting in processing facilities in ozone and the wound surface 1% solution powergra (Getnew A. M. , Kalmykova A. C. Prospects for integrated use of powergra and ozone for nosocomial infection in surgical hospitals //Silver in medicine, biology and engineering. - Novosibirsk, 1996. - Vol.5. - S. 80-84).

The disadvantage of this method is that the ozone is used as a bactericidal agent for air purification dressing and chambers, thereby reducing the microbial contamination of the patients with purulent wounds without bandages in the room working with ozone, generating ozone from 0.2 to 3.5 mg/h in these areas can be created ozone concentrations exceeding the limits of 0.1 mg/m3(Bed, 1981. - So 17. - S. 249).

The objective of the invention is to accelerate the timing of rehabilitation of chronic wounds.

The problem is solved in that in the proposed method of treatment of purulent wounds produce air ozonation environment and the surface of the wound, including locally, then the treatment of wounds is carried out with a mixture prepared ex tempore of ozonated water obtained by passing through it an ozone-oxygen mixture at a concentration of 200 g/l and solution powergra in a concentration of from 0.1 to 0.3%, and then put a bandage impregnated with the same mixture.

The use of air ozonation wound surface and processing it with a mixture of low concentrations of an aqueous solution of powergra and ozonated water and ozone treatment environment can be successfully and quickly sanitize nonhealing purulent wounds, sores, infected polyetheretherketone mixed microflora. This makes it possible to avoid the toxic effects of high concentrations of ozone and more economical use of cerebros the de are bandaging wounds (dressing, chamber), sanitize ozone. After removing the bandages and dressing wounds, limb open wound or area with decubitus placed in a plastic chamber (bag). The wound surface is treated with ozone, through which the tube is fed into the chamber from ozone at a concentration of 200 g/l for 20-30 minutes Then the wound is washed with a mixture of solutions powergra (GOS.reg. 97/167/27; Pharm. senior 42-2845-97 appr. may 27, 1997) at a final concentration of 0.1% to 0.3% and ozonated water, prepared ex tempore by passing through it an ozone-oxygen mixture at a concentration of 200 g/L.

After recovery of the wound on its surface dressings impregnated with the same mixture. Such a treatment of the wound conduct daily dressings, until complete epithelialization or to rehabilitation wounds and preparation for skin grafting.

Example 1. Patient I., 42 years, (I. B. 2636) was treated in Sarnico for a recurrence of a brain tumor. Her operation was performed: removal of a tumor of the middle cranial fossa to the left. In the postoperative period in the rump formed decubitus ulcer size HH cm, the bottom of the wound was the sacrum, there was a great number of purulent discharge, which was isolated Proteus vulgaris (resistant to 18 antibiotics).

To DNEVNOY 30 min treatment of bedsore gaseous ozone, and then the wound was filtered prepared ex tempore by a mixture of ozonized distilled water and powergel and overlap bandage impregnated with this mixture. On the 10th day the wound was cleansed, detachable became serous, scarce, appeared sporadic fresh granulation, began marginal epithelization. Three weeks after the start of treatment decubitus ulcer decreased to the size HH,5 see the bottom of the wound is covered with fresh granulation, is edge epithelialization, wound contraction. Thus, through the month inflammatory process docked, detachable no, the wound is almost completely epithelials. The patient was discharged home.

Example 2. Patient U., 30 years, (I. B. 205) was treated in Sarnico about polytrauma: an indoor posterior dislocation of left tibia, fracture of head of left fibula, fracture of left radial bone in a typical place, ripped here-contused wound size h cm in the upper third of the left tibia, closed trauma to the skull, concussion, shock II degree. After primary surgical treatment of wounds without the trim flap perforated leather and excision of subcutaneous tissue in the month was held the traditional treatment using antibiotics. Formed dry necrosis is inoe purulent discharge, of which is allocated to Staphylococcus aureus in Association with Enterobacter agglomerans (resistant 15-18 antibiotics).

On the 8th day after the start of treatment approach appeared fresh granulation was drastically reduced purulent discharge, then began marginal epithelization. After 2.5 weeks, the wound had completely cleared of pus, inflammation docked, the size of the wound decreased to HK,1 see the Wound is prepared for skin grafting. After surgery, the sutures were removed on the 10th day, healing by first intention.

The method applied in the treatment of 63 patients with post-traumatic suppurative complications, nonhealing wounds, the area of which ranged from 10 to 600 cm2and was often covered with necrotic masses. Nine patients had 2-3 wounds. From wound stood out polyetheretherketone microorganisms. All patients continuously and unsuccessfully treated with antibiotics.

After treatment by the proposed method, after 2-5 days decreased purulent discharge, appeared fresh granulation, began marginal epithelization and wound cleansing from purulent discharge. Thus, in the treatment by the proposed method achieved the healing of pathological PTS the Medical and clinical effectiveness of the proposed method is:

- to reduce the risk of spread of hospital infections;

- successful in the treatment of nonhealing purulent post-traumatic wounds without the use of expensive antibiotics;

- in shortening the hospital stay for 10-12 days.

The method of treatment of purulent wounds, including air ozonation environment and the treatment of wounds by poviargol, characterized in that after ozonation environment and RAS process RAS mixture prepared ex tempore of ozonated water obtained by passing through it an ozone-oxygen mixture at a concentration of 200 g/l and solution powergra in a concentration of from 0.1 to 0.3%, and then put a bandage impregnated with the same mixture.

 

Same patents:
The invention relates to medicine, namely to wound healing tools, and can be used for treatment of burns

The invention relates to medicine, namely to the means for treatment based on blood, and can be used in the treatment of patients with defects in epithelial tissues of different etiology
The invention relates to medicine and can be used for the treatment and prevention of the development of hypertrophic scars and keloids
The invention relates to medicine and can be used in dermatology and surgery for the treatment of boils
The invention relates to medicine, namely to hydrocolloid application to coatings based on chitosan containing polyvinyl alcohol, chitosan, organic acid, the biologically active substance, glutaric aldehyde, ethyl alcohol and water, is intended for use in the treatment process to accelerate epithelialization of wounds of different origin and localization on the body, as a means of preventing the formation of hypertrophic and keloid scars, improve trophism of the skin and mucous membranes, can be used hyperkeratosis, age-related pathology of the skin
The invention relates to medicine and can be used for the treatment of wounds of the skin and soft tissues

The invention relates to medicine, namely to veterinary medicine, and can be used for ointments and their subsequent application in the treatment of infected wounds
The invention relates to experimental medicine and can be used to treat a wide circular burns IIIB-IV in a mammal in experiment

The invention relates to medicine, namely to surgery, and may be applicable to the treatment of purulent-inflammatory diseases of the skin and subcutaneous tissue

The invention relates to medicine and can be used for external use of medicinal liquids

The invention relates to medicine and can be used in surgery, dentistry, gynecology, traumatology, sports medicine, at home, with operating procedures and the damage associated with bleeding, especially in the presence of infection
The invention relates to medicine, in particular as antiviral composition for the treatment of HIV-infected patients with high viral load
The invention relates to biologically active composition based on chitosan and can be used in medicine, cosmetics and food industry, because it is a potent stimulator healing of surface wounds - burns, ulcers and other, relieves skin irritation, quickly restores the skin of bedsores patients
The invention relates to medicine and can be used for inactivation of infectious activity of viruses and bacteria

The invention relates to pharmacology and medicine and can be used to treat patients infected with HIV and other viruses, and relates to antiviral compositions, method of activation to its active ingredients and treatment of HIV-infected patients using this composition

The invention relates to veterinary medicine

The invention relates to the field of medicine and biology, and in particular to substances with cytotoxic and bactericidal activity, and can be used for medicine, veterinary medicine and in the pharmaceutical industry

The invention relates to medicine and can be used to inhibit the hemolytic activity of pathogenic strains of E. coli
The invention relates to medicine and cosmetic industry and relates to curative and preventive cosmetic

Antiarrhythmic drug // 2223759
The invention relates to the field of medicine and relates to anti-arrhythmic drug
Up!