The biologically active substance is a biologically active food supplement, pharmaceutical drug, biologically active additive for animal feed, veterinary medicine, fertilizer, activator microbiological processes, oral food, perfume and cosmetic, hygienic means, dairy products, confectionery, bakery products, vegetable oil and fat product, sauce, alcoholic drink, soft drink, fish product, meat product, pasta, chewing gum, beer

 

(57) Abstract:

Group of inventions relates to food, biotech and medical industries, in particular to the field of biologically active agents, and can be used in the pharmaceutical industry, agriculture, particularly crop and livestock production in various sectors of the food industry and cosmetic industry. The biologically active substance is a protein hydrolysate obtained by acid hydrolysis and subsequent neutralization peptidebased animal raw material, selected from the series: animal carcasses or fish, albumin, blood, animals or fish, meat or fish, prodeinotherium waste during the production of animals or fish, filtration to obtain a hydrolyzate and the precipitate, followed by drying the hydrolysate, with the finished product contains peptides with a molecular weight above 3000 daltons, less than 25 wt. %, optical activity20Dthe finished product is 5-15, the ratio of amine nitrogen : fatty acids : carbohydrate is(10-30):(0,2-2): (0,4-5), and it also contains sodium, chromium, Nickel, cobalt, selenium, calcium, potassium, sulfur, phosphorus,biologically active food supplements, pharmaceutical drug, biologically active additives for animal feed, veterinary drugs, fertilizers, activator microbiological processes, oral nutrition, perfumes and cosmetics, hygiene products, dairy products, confectionery products, bakery products, oil and fat product, sauce, alcoholic drink, soft drink, fish product, meat product, pasta, chewing gum, beer. This allows to obtain universal substance, due to the wide spectrum of its use and non-waste received. As well as the chemical composition of BAS has a great affinity at the cellular level, human cells, animal and plant, which is provided by the molecular weight of peptides and optical density of BAS. In addition to physico-chemical indicators for the biological activity of this substance when introduced into other products imparts to the finished products with high technological properties, for example: increase the shelf life of products, increase product stability, structural and rheological properties with high water-holding capacity. 22 C. and 50 C. p. F.-ly.

production of biologically active agents, and can be used in the pharmaceutical industry, agriculture, particularly crop and livestock production in various sectors of the food industry and cosmetic industry.

The deteriorating environmental situation environment social conditions of people's lives, as well as a reduction in the diet of valuable substances, such as vitamins, macro - and micronutrients, dietary fiber, proteins, etc. reduce the life expectancy of people and the deterioration of the health status of the population.

To solve these problems, the researchers suggest in the diet of a person to enter complexes of biologically active substances from natural sources, in the form of separate concentrates, and in the form of food products enriched with biologically active substances.

This new direction, the edge with a number of related Sciences: the science of nutrition, pharmacology, animal husbandry.

As shown by the analysis of the prior art, in recent years very actively developing direction of the processing of natural raw materials for the production of biologically active complexes. As a natural raw material used peptidomimetic substances, microorganisms, vegetables, etc.

The prior art mineralokeramicheskie substrate having a property of a biological pacemaker, which represents a protein hydrolysate obtained by grinding of raw materials (protein-rich waste products livestock), acid hydrolysis of the feedstock in 5-20% sulfuric acid for 5-15 hours at a temperature of 90-110oWith subsequent filtration of acid hydrolysate, followed by alkaline hydrolysis of the residue does not dissolve in acid, calcium oxide at 95-105oC for 3-5 h, the mixing and stirring the acid and alkaline hydrolysates, pH correction (if necessary), filtration and freeze-drying of the final solution (MOS), while it has the following composition, wt.%: amino acids 65-67 including, free amino acids: aspartic 7,32, threonine 0,69, serine 1,38, glutamic 3,88, valine 1,73, Proline 5,22, methionine 0.89, alanine 2,39, leucine 1,13, isoleucine 0,56, histidine 22,16, phenylanine 0,61, arginine 1,56, lysine 1,28, fats 18-20, lipids, non-fat 2-2,5, carbohydrates 8-11, organic and inorganic salts of 0.5-2, macronutrients 0,2-2, including, mg/g: calcium 5,72, potassium 7,13, sulfur 24,09, phosphorus 19,15, chlorine 2,0, minerals 0,0005-0,009, including e food cake mix, in which whole blood slaughter of animals mixed with sugar and water in a ratio of 1:(3-4): (0,1-0,6) and sterilize the mixture at 105-110oC for 2-3 min (USSR author's certificate 1729387, class. And 23 J 1/06, 1992).

The disadvantages of the method are a product with a high enough quality and biological value.

Also known is a method of obtaining food cake mix from the blood of slaughtered animals, where the formed elements of blood, pre-haemolytic solution of hydrochloric acid with a concentration of 0.20-0.25 mol/DM3ratio: 1: 1, 3-5 min, mixed with sugar and the mixture is evaporated to the dry matter content of 58-62%, then enter the syrup, mix food bone fat and vegetable oil, followed by heat treatment at 75-80oWith over 8-12 min with subsequent cooling to 38-42oC, and after cooling, bring food additives: honey, ascorbic acid and flavouring in the following ratio of ingredients, wt.%: haemolytic the formed elements of the blood, 40-45, a mixture of food bone fat and vegetable oil - 4-5, sugar - 45-50, syrup - 3-4, honey - 2-3, ascorbic acid - 0,04-0,05, flavor - 0,02-0,03 (RF patent 2126215).

Known biologically active pharmaceutical natural product of nature, which contains an acid hydrolysate of Mytilus species, containing amino acids, melanoidins and traces elements of Mytilus edulis and Mytilus galloprovincialis (DE 19934309339, 19930317 AND 61 TO 35/56). Additionally, the invention includes different ways to use this product. In particular, is used as a prophylactic, therapeutic radiopharmaceutical agent for humans and animals, has antipyretic effect, stimulates regenerative processes after the operation, the production of blood especially in radio and chemo therapy. The product has a proven effect in terms of psychological and/or physical stress, as well as a geroprotector.

It is known the use of peptides as stimulator mineral absorption and to prevent hyperlipidemia and hypercholesterolemia (patent EP 07913 which contain at least 20 moles or more acidic ammo acids, used in the manufacture of medicaments for the stimulation of putting in the absorption of minerals, such as calcium or iron, or for the prevention or treatment of hyperlipidemia and hypercholesterolemia. Peptides receive enzymatic hydrolysis of vegetable proteins (19930317 And 61 To 35/56).

As shown by the analysis of the above sources of information, the range of practical use of known biologically active substances is limited.

As a biologically active substance, in accordance with the invention, is a substance of animal origin, further analysis of the prior art is carried out with consideration given direction.

The group of inventions relates to biologically active substances, biologically active additives to food for human and animal pharmaceutical and veterinary preparations, various food, cosmetic and hygiene products containing the biologically active substance, which are used to normalize the physiological state of the organism. As well as the group of inventions relates to fertilizers and activator of microbiological processes, plant growth and plant cells containing a biologically active substance.

the active agent (BASS), possessing immunomodulatory property, which is obtained by grinding and homogenization of raw materials from animal tissue, then from the homogenate allocate containing cell membrane residue, which after resuspendable receive components of cell membranes, is used as raw material of animal tissue, a modified during embryogenesis, and/or proliferation and/or differentiation of cells, and/or pathology, preceded and/or accompanied regeneration and/or repair tissue, homogenate of which is not clear from the destroyed elements of the tissue by filtration and/or centrifugation during acceleration 150-250 g for 10-15 min and produce sediment, contains the cell membrane, which is subjected to hydrolysis, the products of hydrolysis filtered and/or centrifuged at acceleration over 1500 g for 20-40 min emitting supernatant of the hydrolysis products containing components of cell membranes as the target product (RF patent 2041717). BASS contains organic compounds include peptides, amino acids, carbohydrates, lipids, nucleotides and other organic compounds in certain ratios by weight. Derived biologically active agent in a quantity of 0.001-85,0 wt.% use activity which contains a filler (physiological solution of sodium chloride, and/or salt buffer solution, and/or carbohydrate compounds, and/or fats, mineral, animal, vegetable or synthetic origin, and mixtures thereof), and may also contain a preservative.

In relation to biologically active food supplements, the closest technical solution is a protein Supplement which is obtained by freezing and grinding raw materials of animal origin, extraction of biologically active substances water-salt solution, where the water-salt solution using 1-2,5% solution of sodium carbonate at a ratio of volumes of raw materials and a solution of sodium carbonate in the range from 1:8 to 1: 20, and the extraction is carried out at a pH of 10.4 and 10.8 for 2-4 h in the presence of magnesium chloride in an amount of 0.1 to 0.5%, then the obtained extract is acidified to a pH of 3.8 to 5.5, then remove the ballast substances, rinse the precipitate with an organic solvent and dried at a temperature not exceeding 55oWith the molecular mass of the incoming in addition nucleoprotein components is within 10000-90000 Yes (RF patent 2075944).

The disadvantages of the known technical solutions are of low biological value and a narrow range of prokovich diseases, includes at least three active compounds present in the circulatory system: at least one amino acid, at least one vitamin and at least one component selected from the group consisting of adenine, 2-deoxyribose, D-mannose, D-glucosamine, malic acid, salewoman acid, ATP and/or their pharmaceutically acceptable salts, considering the fact that if the composition contains, in addition to amino acids, only malic acid and vitamin, the vitamin may not be ascorbic acid (RF patent 2138257).

The closest technical solution for pharmaceutical drug is a drug for the prophylaxis and/or treatment of diseases, containing the active principle and a pharmaceutically acceptable carrier, where the active agent contains an effective amount of the dipeptide L-Lys-L-Glu or chemical modification in the form of salts (patent RF 2139085).

As shown by the analysis of the prior art in respect of biologically active additives for animal feed, it became very widespread.

Thus the prior art feed additive containing choline and methionine, Treo the following relation, % diet: choline - 0,08-0,12, methionine - 0,13-0,16, threonine - 0,13-0,16 (RF patent 2131678).

Known feed additive possessing biological activity, obtained by extraction of nutrients in one metal salt solution under heat and high pressure and subsequent heat treatment at a temperature not lower than 450oWith not less than 20 min (RF patent 2151521, 2000).

Known preventive fodder bioconcentrate, which contains the drug bifidobacteria and Lactobacillus acidophilus, syrup of lactulose in the following ratio, wt.%: the preparation of bifidobacteria and Lactobacillus acidophilus - 1,2-92,3, syrup lactulose - else, while an additional may contain vitamins such as a and/or group D and/or E and/or K and/or group b and/or C and/or N in the amount of 0.0001-12 wt.%, trace elements in quantities of 0.001-0.8 wt. %, amino acids such as methionine, in an amount of 0.6-20.0 wt.% (RF patent 2123346).

The prior art additive in animal feed consisting of copper sulfate, zinc sulfate, magnesium sulfate, sulfate, selenium, sulfate Germany, rare earth composition and amino acids, which are subjected to special treatment (CN, 1101799, 26.04.1985).

Additive for food home gilotynowych needles and materials of Chinese medicine, to mix and further processed (CN, 1173292, 18.02.1998).

The disadvantages of these feed additives is that they can be used only as a Supplement to a balanced diet.

Known methods for producing protein feed additives of keratin and collagen containing raw materials by enzymatic hydrolysis with proteolytic enzymes (see SU, ed. St. 1517005, 1989; SU, ed. St. 1554173, RF patent 2133097).

The disadvantages of this technology are high energy intensity and duration of the hydrolysis process, and the use of scarce enzyme systems

The closest technical solution to declared biologically active additive for animal feed will be biologically active drug for horses, including species-specific protein which it contains products of cultivation-induced lymphoid cells horses, proteins, amino acids, salts of mineral acids, and optionally, fatty acids, sugars, ascorbic acid, water in the following ratio, wt. %: protein of 5.0-60.0 sec, amino acids, 1,6-5,0, fatty acids 0,10-12,0, sugar 2,0-20,0, ascorbic acid and 0.6 to 10.0, water 1,0-5,0, salts of mineral acids - octalin The prior art feed additive, which composition refers to the veterinary products containing biologically active ingredient of natural origin, characterized in that it further comprises an antibiotic, as a biologically active ingredient of natural origin used biosorbent yeast-based table and sparkling wines, and the surface of the particles of the additive has the electrokinetic potential of not less than 10 mV, the content of the antibiotic is 5-50 g per 1 kg of the additive, and as an antibiotic used derivatives of tetracycline (RF patent 2131677).

Also the prior art food product for Pets, primarily cats and dogs, consisting of edible particles and edible shell, the particles consist of a mixture of hydrocarbons, proteins, fats, fiber and minerals, and may also include veterinary medicines, vitamins, trace elements, amino acids preservatives, antioxidants and flavoring (DE 19610389, 10.07.1997).

Known peptides that consist of several molecules of amino acids and having molecularly weight from 2500 to 10,000 daltons and isoelectrically point between pH 8-11, they are obtained by extraction from moosavi in veterinary medicine for the treatment of man (DE 3325689, 17.01.1985). This veterinary drug accepted as the closest analogue to declare a veterinary drug.

A disadvantage of the known technical solution is a narrow spectrum of action.

Known activator of microbiological processes, plant growth and plant cells containing a mixture of three chemical compounds belonging to the group of ammonium salts alloxanic acids, taken in the ratio 0,1 : 10,0 0,1 : 10,0 : 0,1 : 10 when the total amount of the mixture 1x10-10, 1x10-1 g per 1 g of the obtained or processed biomass (EN, 2092547). This activator is adopted as the closest analogue in respect of the activator microbiological processes, plant growth and plant cells.

The closest technical solution, in relation to fertilizer is fertilizer, which is obtained by mixing the algal and animal (aquatic) raw materials with additional botanicals, followed by fermentation of the mixture at 20-38oWith over 28-48 h, fermented mass is boiled at 75-85oC for 5-15 min, apressofymay cooked mass to obtain a liquid fraction and pulp is separated from the liquid fraction of the fat to fat add waste grow the particular liquid fraction add preservative, cool and freeze the pulp is dried to a residual mass fraction of water 10% (RF patent 2095005, 1995).

The disadvantage of this solution is that the resulting product is not ready for immediate use.

It is well known that deficiencies in the structure and quality of the food accompanied by the inability of the relevant protective systems of the body to adequately respond to the adverse effects of the environment, which dramatically increases the risk of many diseases. Therefore, restoring the structure of power, improve its quality and safety is currently one of the most important and priority tasks.

As well known food mixture for adaptation of the organism to stress, which is obtained by mixing glucose, fructose, oligo - and polysaccharides, amino acid ligand, potassium chloride and water or fruit juice (US, patent, 5270297, class. And 23 L 3/08, 1993).

Disadvantages are getting a product with a short shelf-life and the impossibility of its application to adapt to the conditions of the hermetic isolation of the organism from the external environment by promoting urine formation, and intestinal peristalsis.

Known nutrient composition on the (US, 4368204, 11.01.1983).

The closest technical solution, in relation to oral nutrition, will be acceptable formula of the main power supply, which is suitable for a person with specific dietary requirements (US, 6245803, 12.06.2001). Way to support nutrition for the person suffering from food protein allergens, predusmatrivaet the use of the composition as a sole source of nutrition, consisting of: carbohydrate component in the amount of 38-56% cal. of the total content; the fat component in the amount of 38-50% cal; free amino acid components in an amount of 10-20% in the feces. Thus the composition may further contain vitamins, micro - and macro-elements.

The disadvantage of this product is that it has a low biological value.

The prior art is widely known, the introduction of various biologically active components in the composition of cosmetic products that contribute to turgor of the skin, smoothing out wrinkles, giving the skin a fresh and velvety [ed. St. N 822824, 1979, ed. St. N 822825, 1979, ed. St. 1335288, 1985].

Also widespread cosmetic products containing substances isolated from various Ogadenia, amino acids, cocoa butter, glycerine, emulsifier, mineral salts, vitamins, preservative and water [RF patent 2013088, 1994].

Well-known cosmetic preparations containing polypeptides of collagen and elastin [U.S. patent 4585797, 1986].

Known cosmetic product containing a cosmetic basis, suitable for external use in the form of a lotion, gel, cream or ointment, and bioactive substance obtained from animal organs and tissues, a complex of polypeptides with mol. m 1000-10000 Yes sufficient for the manifestation of its biological activity and of 0.1-2.0% of the cosmetic foundations [RF patent 2161974]. This tool is taken as the closest analogue in relation to cosmetic products.

The disadvantage of this product is its low biological activity.

Currently, the composition of hygiene products such as shampoos, containing a surfactant, is widely includes various components that create an enabling environment for hair growth and normal functioning of the skin.

Known means for washing the hair, which contains lactic acid, oily extracts of the low-melting fraction mink W is dostatkom this well-known detergent is: use an expensive lactic acid and necessity in the preparation of shampoo additional component to reduce the acidity of shampoo.

The closest technical solution, in relation to hygiene, will be detergent containing concentrate deproteinizing whey and additionally sulfosalicylate, glycerine, formaldehyde, ethyl alcohol (Veh. St. USSR 1342503).

The disadvantage of this known detergent is: using concentrate deproteinizing breast serum-free useful protein which is not enough helps to maintain skin and hair in good condition.

The closest technical solution, in relation to bakery products are bakery products obtained by kneading dough from flour, water, yeast, protein supplementation, which is used ledbelly complex from pea in the amount of 2.5 to 4.5% of dry substance to the weight of flour in the dough, and other components, provided the recipe (RF patent 2098966).

Known confection and chocolate, which contains cocoa mass, cocoa butter, soy phosphatidyl concentrate and powdered sugar, soy milk powder and balm "Nazir" (patent of the Russian Federation 2128445). While soy milk powder is injected as a valuable source of protein and essential amino acids.

Terek product including protein fortifier, which is used as the protein hydrolysate of gelatin, sweetening component, milk powder, flavouring, contains lecithin, alcohol extract of Eleutherococcus with a solids content of 5%, food deodorized vegetable oil and water (patent RF 2043731).

The disadvantage of this confection is a low biological value.

Famous mayonnaise, which includes vegetable protein, dried skimmed milk, sodium alginate, mustard powder, drinking soda, salt, sugar, vegetable oil and water. To obtain such a mayonnaise separately prepared water-protein mixture, which 3,0-3,5% vegetable protein mixed with water at 35-40oWith the ratio of 1:7. The mixture is intensively stirred for 2-5 minutes Then in the slurry, add 0.3 to 0.5% of sodium alginate and water in the ratio 1: (10-15), then it is pasteurized at 60-65oC and stirring for 15-20 min and cooled to 30-35oC. the Obtained suspension is injected into the mayonnaise in the number of 24-28% of the total mass. At the same time preparing milk mustard paste. For its preparation 1,0-1,5% mustard powder and 2,5-3,0% skimmed milk powder mixed with water is but mustard paste pasteurized at 90-95oC for 15-20 min and then cooled to 35-40oC. Chilled dairy-horticul pasta and water-protein suspension is mixed and the obtained mixture at 20-25oWith gradually add 30-40% deodorized vegetable oil and 12-14% solution of acetic acid 6% concentration. Next, the emulsion is homogenized at a pressure of 1.05-2.0 MPa and Packed (USSR author's certificate 11194370, 1984).

The disadvantages of this mayonnaise is the need to introduce a large number of vegetable protein, which gives the product a foreign flavor of munisteri and grayish shade, multi-stage and duration of the technological process of obtaining, due to the separate preparation of the two mixtures and separate pasteurization.

There is mayonnaise, containing vegetable oil, egg and mustard powders, dry cheese whey or whey protein concentrate, sodium alginate, glucose-fructose syrup or sucrose drinking soda, acetic acid, salt. For making it take (0.3 to 1.0)% of sodium alginate and (1,5-2,2)% sucrose, which is dissolved in water at 35-40oC. Then, in the same capacity add 1.6 to 4.0 percent dry whey, 0.03-0.05% of drinking soda, 1.0 to 1.5% of salt is the cooled to 30-35oAnd it consistently give 35-47% vegetable oil and 0,55-0,75% acetic acid 80% concentration. The resulting emulsion is homogenized at a pressure of 2.5 to 5.0 MPa and Packed (USSR author's certificate 1287833, 1987).

The disadvantage of this mayonnaise is the need for strict adherence to the sequence of input components in predetermined ratios, as otherwise the finished product acquires the consistency, not typical mayonnaise.

Closest to the proposed invention to the technical essence and the achieved result, in relation to the subject - the sauce is a sauce type mayonnaise, which along with dry skim milk injected protein concentrate whey in the following ratio, wt.%: vegetable oil 30-65,40, egg powder of 0.01-4,50, skim milk 0,01-6,55, protein concentrate whey 0,50-7,00, dry mustard 0.25 to 2.50, the sugar 0,26-3,50, salt 0,90-2,00, baking soda 0,04-0,10, acetic acid or citric 0,65-1,25, flavorings and fillers 0,001-50,00, water - the rest (USSR author's certificate 1243687, 1983).

Mayonnaise sauce is prepared as follows. In the capacity serves mustard powder and fill it with water is the water is added, the dry protein concentrate of whey, egg powder, skimmed milk powder, baking soda, salt, granulated sugar and heated to 85-90oWith, maintaining the resulting mixture at this temperature for 15-20 minutes when the composition of mayonnaise is egg powder, the mixture is heated to 60oC to prevent denaturation of the protein. After pasteurization, and dissolution of all components in the mixture is cooled to 25-30oWith and with constant stirring a squirt enter a deodorized vegetable oil. Then after a homogeneous stable emulsion injected a solution of acetic or citric acid, flavours or fillers. All carefully mix for 5-7 minutes, homogenized at a pressure of 1.0-3.0 MPa and packaged.

The disadvantages of this mayonnaise are: mandatory joint input of skimmed milk powder and protein concentrate whey; significant consumption of skimmed milk powder (up 6,55%) and protein concentrate whey (to 7.0%); low biological value; not satisfactory rheological parameters of mayonnaise and its storage stability.

As shown by the analysis of the level technousa desired color and do not have undesirable taste, it contains 5-100%, preferably 25-35% of the USRDI (daily consumption) of iron, and mentioned iron is an iron chelated with amino acids, or encapsulated ferrous sulfate, 5-100% of the USRDI of zinc, preferably in the form of zinc gluconate, about 0.001-0.05% of a coloring agent, preferably selected from the group consisting of yellow dye Lake, Yellow # 6, red dye Lake Red #40, blue dye Blue Lake #1, Riboflavin, beta-carotene and mixtures thereof, optionally, up to 98%, preferably 10-98% sweetener, preferably sugar, 0.001 to 10%, preferably 3-5% flavoring agent, and mentioned flavoring agent selected from fruit or Botanical flavouring substances or mixtures thereof, preferably from the group consisting of flavorings "Jamaica", "mango", "orange", "lemon-lime", "strawberry", "peach", "lemon", lime and mixtures thereof, and 1-50% of the edible acid, preferably selected from the group consisting of citric acid, malic acid, tartaric acid, lactic acid and their mixtures (RF application 98109944).

The closest technical solution in respect of non-alcoholic beverage will be bezalkagolny drink rehabilitation actions containing fruit juice, mono - and/or diseny composition of mineral-organic substrate lenkin, because the raw material for its production is molepolole water-soluble substance, which is formed in the bowels of the earth crust and mined as ore from the rock.

Regarding alcoholic drink, the closest technical solution is vodka special "Polski souvenir", includes 1000 gave the finished drink: honey bees - 30 kg, aromatic spirit of rye malt - 500 l and aqueous-alcoholic liquid. The ratio of dry rye malt to alcohol ethyl alcohol upon receipt of the aromatic alcohol rye malt is /0,18-0,22/: 1, which allows to enrich vodka amylolytic enzymes and amino acids, which would contribute to the breakdown of starch in the human body to easily digestible dextrins and maltose, thereby improving digestion and the functioning of the human body (patent RF 2112796).

The disadvantage is low organoleptic quality of the product.

The closest technical solution against the butter-fat product is margarine containing tallow, vegetable oil, emulsifier, coloring, dairy products, flavoring additives, and water, as a solid fat it contains hydrogenated fat food with SUP>oWith and hardness 160-600 g/cm and a melting point 37-47oWith and hardness 600-1000 g/cm, and in the quality of dairy products - milk powder and/or dry cheese whey and/or whey protein concentrate, and/or dry cream, and/or "BK-lacto" (patent of the Russian Federation 2110184).

The disadvantage is the low biological value.

The prior art enriched fish product, which is obtained by processing fish raw or semi-finished products activator, a refinery, a stabilizer or their carriers, and the Ambassador of fish raw materials, as activators, supplements, stabilizers apply carbohydrates, hydrocarbons, nitrogen and mineral substances, their derivatives or mixtures (RF patent 2054875). This product is adopted as the closest analogue in the fisheries of the product.

The disadvantage is the low biological value.

In respect of a meat product, the closest technical solution is a meat product in the form of pashtetnoyi mass for therapeutic products obtained by pre-treatment at a temperature of 60-65oC for 2 h and grinding of raw meat, preparing meat and then adding Oia shells, cooking loaves and cooling the raw meat used beef second grade and mesomechanical dabwali (MMD) pork, as well as the protein component of lentil flour, pre-soaked in blood plasma in a ratio of 1:1 for 1.5-2.0 hours at a temperature of 20-22oWith, at the stage of preparation of meat additionally make pumpkin powder milk mix (PTMP), hydrated in water at a ratio of 1:1 at a temperature of 20-22oTo achieve a uniform consistency (RF patent 2137403). The presence in the composition of blood plasma enriches soluble easily digestible protein.

The disadvantage of this product is low organoleptic properties.

The prior art pasta fast food containing flour, liquid, salt and seasonings, biologically active cuspidate additives and/or preservatives and/or vitamins, while the liquid phase is velociraptorinae aqueous solution, at the same time as bloggericedream solution using a broth of meat and/or chicken concentrates, and/or egg powder or protein of eggs and/or milk powder and starch-containing element (RF application 97104449). E is rigid, that put bloggericedream supplements do not provide the product with high organoleptic characteristics.

The closest technical solution, in relation to chewing gum is a chewing gum containing a flavoring, flavouring, chewing basis and food acid (patent US 4931293, 14.11.1988).

The disadvantage is the low biological activity.

Famous drink of the beer type, in which the wort is produced from glucose syrup based on starch, soluble protein material, water and hops, with glucose syrup based on starch obtained from wheat, potatoes, maize, sorghum, barley, rice or tapioca, and soluble protein material contains at least one amino acid selected from the following group: glutamine, aspartic acid, asparagine, glutamic acid, series, threonine, lysine and arginine, and in which the composition and concentration of amino acids are sufficient for carrying out the process of fermentation with brewer's yeast (RF application 2000115726). This drink is adopted as the closest analogue in respect of beer.

The disadvantage of this product is its low biological Cena, which is stable and can be easily introduced in the pharmaceutical or veterinary drugs, dietary supplements for humans and animals, as well as in foodstuffs and cosmetic preparations in solid form and in the form of any convenient solution.

This is achieved by obtaining biologically active substances (BAS), which can be used as a dietary food Supplement and is a protein hydrolysate obtained by acid hydrolysis and subsequent neutralization peptidebased animal raw material, selected from the series: animal carcasses or fish, albumin, blood, animals or fish, meat or fish, prodeinotherium waste during the production of animals or fish, filtration to obtain a hydrolyzate and the precipitate, followed by drying the hydrolysate, with the finished product contains peptides with a molecular weight above 3000 daltons, less than 25 wt.%optical activity20Dthe finished product is 5-15, the ratio of amine nitrogen : fatty acids : carbohydrate is(10-30):(0,2-2):(0,4-5), and it also contains sodium, chromium, Nickel, cobalt, selenium, calcium, potassium, sulfur, phosphorus, chlorine, iron, zinc, copper, manganese.

While carbohydrates are selected from a number of: glucose, fructose, lactose, starch, sucrose, maltose, deoxyribose, soluble and insoluble dietary fiber, inulin, ribose.

Lipids selected from the range: triglycerides, phospholipids, sterols, sterols, microbial lipids.

Vitamins are selected from a number of: vitamin a, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, Niacin, vitamin PP, Niacin, Pantothenic acid, pyridoxine, folic acid, folacin, cyanocobalamin, vitamin C, and vitamin-like substances selected from the range: BIOMIN T, carnitine, vitamin U, lipoic acid, lipoic acid, thioctic acid.

Mineral components selected from a number of: calcium, phosphorus, magnesium, sodium, potassium, sulfur, chlorine, iron, copper, selenium, iodine, chromium, zinc, fluorine, manganese, cobalt, molybdenum, silicon, bromine, silver, boron, vanadium, germanium.

Alkaloids selected from the range: derivatives pyrrolidine, derivatives of piperidine derivatives of pyridine, quinoline derivatives, derivatives of isoquinoline, indole derivatives, imidazole derivatives, purine derivatives, alkaloids, diterpenoid structure, steroid alkaloids, glycoalkaloids, acyclic and peptide alkaloids containing sulphur, urea derivatives.

Glycosides selected from the range: saponins, antraglikozida, bitter glycosides, thioglycoside.

Phenolic compounds selected from the series: simple phenols, penelopie, phenolic acids, coumarins, chromone, lignans, flavonoids, isoflavones, flavanone, flavones, retinoid, tannins, lignin, melanin, humic acid.

Biologically active food Supplement contains enzymes selected from the series: one-component enzymes, the two enzymes.

Terpenoids selected from the range: monoterpene and p is osvitnye.

Biologically active food Supplement contains herbal products, chosen from a number of higher plants, components fractionation of higher plants, lower plants, components fractionation. The components of fractionation products of plant origin may be in the form of tinctures, extracts, decoctions, pressed powder, and can also be obtained by extraction of various extractants.

Products of microbial origin selected from the range: bifidobacteria, lactobacilli, E. coli, yeast, Lactobacillus acidophilus.

Technological additives can be selected from a number of technological components for tabletting, food additives, flavors, sweeteners, preservatives, dyes, liquid.

The pharmaceutical preparation contains a biologically active substance and pharmaceutical base, selected from the series: homeopathic remedies, analgesics, sclerosant, means for correction of disorders in alcoholism, toxic and drug addiction, regenerants referenti, vegetotherapy funds hematotherapy tools, hormones and their antagonists, immunotropic tools, intermediate, necrotrophy the funds technological additives, or their mixture, in the following ratio, wt.%: BAS is 0.0001-50, the pharmaceutical basis of the rest.

This vegetotherapy means selected from the range: adrenolytic funds adrenomimeticescoe tools, cholinolytic drugs, cholinomimetics.

Hematotherapy means selected from the range: antiplatelet agents, anticoagulants, substitutes of plasma and other blood components, fibrinolysis inhibitors, coagulants, blood coagulation factors, hemostatic, stimulators of hematopoiesis, fibrinolitiki.

Hormones and their antagonists selected from the range: androgens, antiandrogens, glucagon and its analogues, the hormones of the hypothalamus, pituitary gonadotropins and their antagonists, thyroid hormones, their analogues and antagonists, anti-thyroid tools, insulin, corticosteroids, estrogens, gestagens, their homologues and antagonists.

Immunotropic means selected from a number of: immunoglobulins, immunosuppressants, immunomodulators.

Intermediate selected from the range: adenosinergic tools, antagonists of angiotensin II receptors, AT1-subtype, histaminergic tools, diaminopimelic, prostaglandins and their antagonists, thromboxane of the series: anabolic steroids, antihypoxants and antioxidants, vitamins and vitamin-like tools, synthetic hypoglycemic and other means, lipid-lowering means, detoxifying remedies, antidotes, proofreaders metabolism of bone and cartilage tissue, macro - and microelements, rehydralyte, regulators of water and electrolyte balance and KHS, means affecting uric acid metabolism, means for enteral and parenteral nutrition, enzymes and encipherment, means that prevent the formation and contributing to the dissolution of calculus.

Neurotropic means selected from the range: anxiolytics, sedatives and sleeping pills, antidepressants, antipsychotics and drugs lithium tonic, tonic and adaptogen, opioids and their analogues and antagonists, ANTIPARKINSONISM funds, antiepileptic drugs, psychostimulants and nootropics, means affecting neuromuscular transmission.

Organotropic means selected from the range: dermatotropnoe tools, gastrointestinal remedies, respiratory means, cardiovascular drugs, antispasmodics myotropic, money, regulate the function of organs of the urogenital system and reproduction.

Protivomikrobnye tools in combination, synthetic antibacterial agents.

Antineoplastic agents selected from the range: alkylating tools, antimetabolites, antitumor antibiotics, antineoplastic hormonal drugs and hormone antagonists, antineoplastic agents of plant origin, including alkaloids.

Analgesics selected from the range: non-steroidal drugs, anti-inflammatory agents.

Technological additives selected from a number of technological components for tabletting, flavorings, flavoring agents, sweeteners, liquid base for the suppository, the basis for films, the basis for gels, hydrophilic base, base for powders, lipophilic base, devilina base, base for ointment form.

Biologically active additive for animal feed contains BAS and a component selected from a number of: carbohydrates, lipids, vitamins, vitamin-like substances, minerals, alkaloids, homeopathic remedies, glycosides, immunoglobulin preparations, phenolic compounds, organic acids, enzymes, terpenoids, hormones and hormone-like substances, cytokines, products of vegetable origin, products mi the VA natural origin, detoxicant, technological additives, or mixtures thereof, in the following ratio, wt.%: BAS - 10-90, component or mixture of components - the rest.

Carbohydrates selected from the range: glucose, fructose, lactose, starch, sucrose, maltose, deoxyribose, soluble and insoluble dietary fiber, inulin, ribose.

Lipids selected from the range: triglycerides, phospholipids, sterols, sterols, microbial lipids.

Vitamins are selected from a number of: vitamin a, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, Niacin, vitamin PP, Niacin, Pantothenic acid, pyridoxine, folic acid, folacin, cyanocobalamin, vitamin C.

Vitamin-like substance selected from the range of: Biotin, bioflavonoids, orotic acid, pangamic acid, paraaminobenzoic acid PABK, choline, Inositol, vitamin T, carnitine, vitamin U, lipoic acid, lipoic acid, thioctic acid.

Mineral components selected from a number of: calcium, phosphorus, magnesium, sodium, potassium, sulfur, chlorine, iron, copper, selenium, iodine, chromium, zinc, fluorine, manganese, cobalt, molybdenum, silicon, bromine, silver, boron, vanadium, germanium.

Alkaloids selected from the range: derivatives pyrrolidine, derivatives of piperidine is asola, derivatives of purine alkaloids diterpene structure, steroid alkaloids, glycoalkaloids, acyclic and peptide alkaloids containing sulphur, urea derivatives.

Glycosides selected from the range: saponins, antraglikozida, bitter glycosides, thioglycoside.

Phenolic compounds selected from the series: simple phenols, penelopie, phenolic acids, coumarins, chromone, lignans, flavonoids, isoflavones, flavanone, flavones, retinoid, tannins, lignin, melanin, humic acid.

The enzymes selected from the series: one-component enzymes, the two enzymes.

Terpenoids selected from the range: monoterpene and their derivatives, sesquiterpenes, diterpenes, sesquiterpene lactones, triterpene saponins, tetraterpene and their derivatives.

Products of vegetable origin is selected from a number of higher plants, components fractionation of higher plants, lower plants, components fractionation of lower plants.

Products of microbial origin selected from the range: bifidobacteria, lactobacilli, E. coli, yeast, Lactobacillus acidophilus.

Technological additives selected from a number of technological components for tabla is rinary the drug contains active substances and pharmaceutical base, selected from the series: homeopathic remedies, analgesics, sclerosant, means for correction of disorders in alcoholism, toxic and drug addiction, regenerants referenti, vegetotherapy funds hematotherapy tools, hormones and their antagonists, immunotropic tools, intermediate, neurotropic tools, organotropic means, an antimicrobial agent, a sedative, anti-cancer agents, processing AIDS, or their mixture, in the following ratio, wt.%: BAS is 0.0001-50, the pharmaceutical basis of the rest.

Vegetotherapy means selected from the range: adrenolytic funds adrenomimeticescoe tools, cholinolytic drugs, cholinomimetics.

Hematotherapy means selected from the range: antiplatelet agents, anticoagulants, substitutes of plasma and other blood components, fibrinolysis inhibitors, coagulants, blood coagulation factors, hemostatic, stimulators of hematopoiesis, fibrinolitiki.

Hormones and their antagonists selected from the range: androgens, antiandrogens, glucagon and its analogues, the hormones of the hypothalamus, pituitary gonadotropins and their antagonists, thyroid hormones, their analogues and ety.

Immunotropic means selected from a number of: immunoglobulins, immunosuppressants, immunomodulators.

Intermediate selected from the range: adenosinergic tools, antagonists of angiotensin II receptors, AT1-subtype, histaminergic tools, diaminopimelic, prostaglandins and their antagonists, thromboxanes and their antagonists, leukotrienes and their antagonists, serotonergic tools.

Metabolite selected from the range: anabolics, antihypoxants and antioxidants, vitamins and vitamin-like tools, synthetic hypoglycemic and other means, lipid-lowering means, detoxifying remedies, antidotes, proofreaders metabolism of bone and cartilage tissue, macro - and microelements, rehydralyte, regulators of water and electrolyte balance and KHS, means affecting uric acid metabolism, means for enteral and parenteral nutrition, enzymes and encipherment, means that prevent the formation and contributing to the dissolution of calculus.

Neurotropic means selected from the range: anxiolytics, sedatives and sleeping pills, antidepressants, antipsychotics and drugs lithium tonic, tonic and adaptogen, opioids and their anisotropy, tools affecting neuromuscular transmission.

Organotropic means selected from the range: dermatotropnoe tools, gastrointestinal remedies, respiratory means, cardiovascular drugs, antispasmodics myotropic, money, regulate the function of organs of the urogenital system and reproduction.

Antimicrobial agents selected from the range of: antibiotics, antiviral agents, antifungal agents, antimicrobial agents in combination, a synthetic antibacterial agents.

Antineoplastic agents selected from the range: alkylating tools, antimetabolites, antitumor antibiotics, antineoplastic hormonal drugs and hormone antagonists, antineoplastic agents of plant origin, including alkaloids.

Analgesics selected from the range: non-steroidal drugs, anti-inflammatory agents.

Technological additives selected from a number of technological components for tabletting, flavorings, flavoring agents, sweeteners, liquid base for the suppository, the basis for gels, the basis for films, the basis for powder, hydrophilic base, lipophilic base, di and receive filtering the precipitate, which is used as fertilizer.

Activator microbiological processes, plant growth and plant cells is the BAS solution with a concentration of 110-1-110-12%.

Oral food contains BAS food and reasonable basis, in the following ratio, wt.%: BAS - 0,001-50, food reasonable basis - the rest.

Perfume and cosmetic contains BAS and cosmetic acceptable basis for external use, selected from the series: module oil-based module based on the emulsion, the module on the base gel, the module on aqueous-alcoholic basis, in the following ratio, wt.%: BAS - up to 20, cosmetics Foundation - the rest.

Hygienic means includes BAS and hygienically acceptable basis for external use, selected from the series: module for toothpaste, a module for shampoo, module for liquid soap, a module for soap, foaming basis, wt.%: BAS - up to 20, cosmetics Foundation - the rest.

Dairy product contains BAS and dairy basis, selected from the range: a dairy unit, curd module, dairy module, in the following ratio to the, is selected from the series: module for candies, module for jelly products, module for marmalade, module soufflé module for Fudge, the module for chocolate, module for Oriental sweets, module for sherbet, in the following ratio, wt.%: BAS - up to 25, the base - rest.

Bread-bakery product contains a substance and a base selected from the series: module for gingerbread, the module for cakes, module for biscuits, module wafer, module for bread, module for bakery products in the following ratio, wt.%: biologically active food Supplement - 40, the base - rest.

The oil and fat product contains substance and the basis chosen from a number of: margarine, butter, vegetable oil, combined oil, butter substitute, fat, in the following ratio, wt.%: BAS - 15, the base - rest.

Sauce, biologically active food Supplement obtained under item 1, and the basis chosen from a number of: a module for mayonnaise, module for ketchup, the module for dressing, module adzhika, soy module, spices, horseradish, mustard, in the following ratio, wt. %: BAS - up to 25, the base - rest.

Alcoholic drink contains BAS and water-alcohol foundations of locally drink contains BAS and the basis selected from the range: drinking water, mineral water, juice, nectar, juice, lemonade, mineral water, non-alcoholic beer, kvass, in the following ratio, wt. %: BAS - 15, the base - rest.

Fish product contains BAS and fish basis, in the following ratio, wt.%: BAS - 40, fish base - the rest.

The meat product contains substance and the basis chosen from a number of: a module for boiled sausage, module boiled-smoked sausages, module for semi-smoked sausages, module for meat products, the module for stuffing, module for raw-smoked sausages, module for sausages, module for wieners, in the following ratio, wt.%: BAS - up to 40, the base - rest.

Pasta containing substance and a test basis, in the following ratio, wt.%: BAS - 35, the test basis - the rest.

Chewing gum contains a BAS module chewing gum, in the following ratio, wt. %: BAS - up to 25 module for chewing gum - rest.

Beer contains BAS and beer basis, in the following ratio, wt.%: BAS - up to 40, the beer base - the rest.

Biologically active substance sadakata, Proline, glycine, alanine, cystine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine.

The technical result of the claimed invention is the versatility of BAS due to the wide spectrum of its use and non-waste received. As well as the chemical composition of BAS has a great affinity at the cellular level, human cells, animal and plant, which is provided by the molecular weight of peptides and optical density of BAS. In addition to physico-chemical indicators for the biological activity of this substance when introduced into other products imparts to the finished products with high technological properties, for example: increase the shelf life of products, increase the stability of the product (beer, soft drinks, sauces, hygiene, fat and dairy products), structural and rheological properties with high water-holding capacity (meat products, bakery products, confectionery and pasta).

Human nutrition is the most important environmental factors throughout life affects the human body. Nutrients into the process MetaPost, define health and longevity. Disturbances in power always lead to various negative consequences. Therefore, rational, appropriate age, professional activity, health food is considered as the most important factor in the prevention of most diseases, including cardiovascular (atherosclerosis, myocardial infarction, stroke, hypertension and others), Oncology, gastrointestinal, metabolic (obesity, low back pain) (So L Pilate and other "Biologically active food Supplement), 2002, S. 11).

For this purpose it is necessary to optimize the human diet to improve health, reduce the risk of disease development, prevention and treatment of diseases in the nutritional composition of events by filling complex of biologically active substances that our body loses due to the abrupt change in power structures; compensation of additional loads on the human body resulting from disease and man-made civilization (urbanization).

Optimization of human nutrition can be achieved as the direct use of biologically active dabanovic functional ingredients.

Therefore, this invention is directed not only to the creation of biologically active substances and biologically active additives to food, but also to receive food with high biological and organoleptic properties.

In this invention under the terms "module" and "basis" should be understood classical composition, acceptable for this product.

Studies have shown that Biologicheskie active substance has hepatocarcinoma activity. Its use promotes more rapid recovery of indicators of blood after application of the cytostatic cyclophosphamide or total gamma irradiation. The most effective is the exchange rate (5-10 days) application. BAS is active as when parenteral application, and when introduced into the stomach. Runepriest application of BAS in doses of 100 and 1000 mg/kg allows to judge about the great breadth of therapeutic doses of the drug. This allows us to recommend BAS to study in the clinic as hemocorrection.

On the basis of biologically active substances and additives was obtained biologically active additive to food. The tests received BAD lady stimulating effect on simpato-adrenal system of the body, optimizing on psycho-physiological functions and processes of adaptation, a normalizing effect on the backup capabilities, mental and physical performance, state night's sleep, it helps to reduce recovery times psychophysiological changes after work. It was also found effective in comparison with control over the use of dietary SUPPLEMENTS to increase the resilience of the human operator when running in extreme conditions of activity. Compared with the control detected a pronounced bioprotective effect of increasing the natural resistance of the human body as in the period preceding activities in special and extreme conditions, and during its execution, as well as in the recovery period.

Was identified bioprotectant and optimizing the effect of SBC on the body's functions and performance of the operator when working in conditions of adverse conditions and working conditions (noise, high and low ambient temperatures, high static loads, psycho-emotional stress, orthostatic stress, high level of functional voltage).

To ascertain the possible functional changes in athletes and professionals operating in adverse environmental conditions. The use of dietary SUPPLEMENTS can serve as a means of improving adaptationist, prevention of occupational fatigue, psycho-physiological and functional changes to prevent chronic exhaustion of functional reserves of the organism.

Two months taking SUPPLEMENTS contributed to the decrease in the rate of biological aging test, increase energy capacity compared with the results of the background research. These preliminary experimental data substantiate the possibility of using SUPPLEMENTS in order to extend the professional longevity of the various contingents.

The use of BAS in the experiment showed that the drug increases the body's resistance and possesses protective properties if the damage Cyclophosphamide and irradiation, promotes faster recovery indicators haematopoietic system, has a stimulating effect on the phagocytic activity of neutrophils. The use of BAS in the study of regularities of chemical carcinogenesis of the gastrointestinal tract in the experiment showed a reduction in the incidence of tumours at 10-12%, which is indicative of protivoorechii skin helped to reduce healing time by 1/3. Pharmaceutical drug can be introduced into the body by injection, inhalation, suppository, sublingual administration, drink, interlego introduction pills, intranasal, or by application to mucous membrane or wound surface in the form of poultices, powders, ointments and gels.

Perfume and cosmetic reasonable basis for external use may be aqueous solutions of alcohols, all types of emulsions, gels and essential fatty basis. The use of one specific bases selected from the group of the above-mentioned substances and biologically active substances allows to create different types of perfume and cosmetic products in accordance with the invention, such as tonics, creams, balms, lotion, skin cleansing cream for nails, massage cream, lipstick, mascara for eye makeup, etc. for daily body care. A particularly good effect when applying a new cosmetic compositions observed in the case when the composition also contains herbal extracts. Choosing the right herbal extract based on known normal use of such extracts in cosmetics with a change in activity SS="ptx2">

Also using the BAS can be obtained by a variety of hygiene products: shampoos, conditioners for hair washing tools for baths, Soaps, toothpastes, elixirs, etc. that also have a high biological properties.

Waste produced during the production of biologically active substances on stage filtration, widely used as fertilizer. Studies have shown that received fertilizer optimally balanced set of macro - and micronutrients.

When using dietary supplements for animal feeding showed that the biologically active components of BAS are in the optimum ratio. Therefore, when using feed containing SUPPLEMENTS, increased international organism of animals and birds, metabolism, leading to increased health and productivity of animals and birds.

Example 1: a Biologically active substance (BAS)

Fish meat is ground and subjected to acid hydrolysis in 15% sulfuric acid to a negative reaction to the protein, then subjected to neutralization and filtration to obtain a hydrolyzate and the precipitate obtained hydrolyzate is subjected to spray drying, with the finished product contains peptides with m is t 8, the ratio of amine nitrogen : fatty acids : carbohydrate is 15: 1,3:2.8 and contains sodium, chromium, Nickel, cobalt, selenium, calcium, potassium, sulfur, phosphorus, chlorine, iron, zinc, copper, manganese.

Example 2: Biologically active food Supplement

Biologically active food Supplement in tablet contains:

BAS - 0.3 grams

Immunoglobulin fraction of human serum - 0.1 g

Bifidobacteria - 0,007 g

Vitamin a - 1650 ME

Vitamin E - 0,005 grams

Vitamin C - 0.05 g

Skimmed milk powder 0.1 g

Flavor - 0.001 g

Calcium stearate - 0.01 g

CMC - Up weight of the tablet 0.55 g

Derived biologically active food Supplement has a high biological value.

Example 3: Pharmaceutical drug

Pharmaceutical preparation in the form of tablets contains:

BAS - 0.2 g

The emoxipin - 0.2 g

Starch - 0.05 g

Talc - 0.05 g

Sugar - 0.5 g

In narcological hospital was testing the use of the drug in the clinic relief of withdrawal hangover disorders.

The drug was performed in 2 groups of 10 people each. In the 1st group was selected patients with mild signs of withdrawal alcohol when security hemodynamics and relatively calm state of health. The drug helped to arrest the disorder without the use of tranquilizers, vitamin therapy and other means of detoxification.

In the 2nd group also selected 10 people with severe withdrawal hangover disorders in the autonomic, SOMATO-vegetative type and mood swings, increased blood pressure, with large periods of binge and with a high degree of tolerance. Taking the drug at a dose of 2 tablets 2 times a day for 7 days allowed in conjunction with detoxification therapy, vitamin therapy to normalize hemodynamic disorders, relieve somatic and autonomic disorders, to create a favorable background mood. In some cases, the drug was accompanied together with the introduction of haloperidol for the night.

Thus, the use of the drug in the practice of alcoholism treatment effectively and requires a further application for the treatment of acute alcoholism.

Example 4: Pharmaceutical drug

Pharmaceutical preparation in the form of tablets contains:

BAS - 0.2 g

Immunoglobulin G man - 0.2 g

Interferon- - 0.02 g

Flavor - 0,005

Magnesium stearate - Up weight of the tablet 0.5 g
BAS 0.1 g

Immunoglobulin G man - 0.05 g

Extract of chamomile flowers - 0.02 g

Polietilenoksidnoy base for suppositories - Before the weight of the suppository 1.4 g

Example 5: Pharmaceutical drug

Pharmaceutical preparation in the form of ointment contains:

BAS - 5.0 g

Streptocide - 5.0 g

Oil-fatty base - 90.0 g

The resulting ointment promotes rapid healing of wounds.

Example 6: a dietary Supplement for animal feed

Biologically active additive for animal feed contains (1 kg):

BAS - 500,

Vitamin-mineral premix - 500g

In horse SUPPLEMENTS are used in a mixture of porridge once a day at a dose of 80 mg/kg of body weight. As shown by tests in horses treated with the BAD, strength is maintained throughout the course of the run. They did not lose the pace of the course at the end of the race, which happened in horses in the control group

Example 7: Veterinary drug

Veterinary drug in the form of powder contains:

BAS - 10 wt.%

Ptacin - 90 wt.%

Received a veterinary drug used for the treatment of calves suffering from gastroenterocolitis. The drug is used inside for 30 minutes before feeding the s is subjected to acid hydrolysis in 19% sulfuric acid to a negative reaction to the protein, then subjected to neutralization and filtration to obtain a hydrolysate and a precipitate, the precipitate is used as fertilizer.

Example 9: the Activator microbiological processes, plant growth and plant cells

We studied the effect of BAS on the processes of callus formation and regeneration in cereal plants. BAS at a concentration of 10-5added to the nutrient medium of Linsmeier and Skoog (when the tissue cultivation of wheat) and Gamborg B5 (when the tissue cultivation of barley). As a control investigated the growing tissues of these cultures in the presence of traditional stimulants (6-BAP, kinetics, and IAA - the study of the effects on regeneration). As shown by the analysis, the number of regenerated plants adding substance to the culture medium in wheat 2 times higher than the control, and barley 2.5 times. It should be noted that the use of BAS in other quantities positive effect is observed to a lesser extent.

Thus, adding to the nutrient medium as a stimulant substance leads to a significant increase in the frequency of callus formation and regeneration.

Example 10: Oral nutrition

Components are prepared by mixing, in the sequential introduction into the mixer loose components and BAS. Mix and thus obtained mixture is Packed in a sealed package and stored until use. The shelf life of the mixture without changes in consumer properties is not less than 2 years. Before use, the mixture was diluted with boiled or disinfected water. The recovered mixture is an opaque liquid, not containing solid phase and which is suitable for use through a system of water intake. A mixture is prepared from a pre-prepared glucose, juice freeze-drying, potassium chloride, citric acid, dry substance, at a ratio of 1:6:2.

Thus, the nutrient mixture of long-term storage has adaptogenic and radioprotective properties.

Example 11: Cosmetic

The oil-based cream that contains: active substance - 0.1, paraffin - 7-11, beeswax - 5-9, ceresin - 4-8, oil extracts of nettle, St. John's wort, chamomile, calendula - 5-10, olive oil - 10-20, fragrance oil - 100.

The resulting cream is easily and evenly glides on skin, absorbs quickly without leaving a film. Has a beneficial effect on the skin, which is associated with the inclusion content of biologically active cobacterial properties of the skin 15.1% /according to alagomeji/. Skin elasticity is increased in terms of elastometry 17%.

Skin after regular use of the cream becomes smooth, elastic, relieves the feeling of tightening after washing, the phenomena of irritation, peeling.

Example 12: Cosmetic

Gel for the face, containing the biologically active substance is 0.5, carbopol - 0,2-0,6, hydroxyethylcellulose - 0,1-1,0, propylene glycol - 1-5, triethanolamine - 0,1-0,6, alcohol-water-glycerin extracts of calendula, chamomile, nettle - 1-4, water up to 100. The tool is prepared as follows.

Biologically active substance in the amount of 0.5% of the cosmetic bases receive the same manner as described in example 1. Components in the reactor are fed through the dispensers. In the reactor consistently contribute components and mix. Gelling components are dispersed in water at 150oC. After swelling and uniform distribution, i.e., the formation of a dispersion, homogeneous mass is neutralized and cooled, with stirring, to room temperature. Then, under stirring, bring the biologically active substance. Then make filtering and filling.

The inventive tool increases the body's resistance to damage is ture persons prevents the destruction of the structure of the fibers of the skin of the face and neck, restores the skin surface and enhances skin elasticity.

Example 13: Hygienic means

To obtain the shampoo in the digester load water in an amount of 7.8 kg and heated to 70oC. When operating the mixer and turned on the heating serves pre-melted monoethanolamide in the amount of 0.5 kg After complete dissolution slowly, in portions with constant stirring served ethoxylated lauryl sulfate in an amount of 2.0 kg Then add gidrometeotsentra calendula in the amount of 0.005 kg, previously dissolved in a little water. The mass is cooled and at 45-50oServed with citric acid in the amount of 0.001 kg, resorcinol 0.05 kg, perfume 0,13 kg, biologically active substance in quantities of 0.5 kg, the dye 0,00025 kg, salt 0.5 kg After cooling, the total weight of the shampoo is ready.

The resulting shampoo stable during storage and has a high biological activity.

Example 14: Dairy product

Dairy product in the form of paste contains, wt%:

BAS - 3

Curd with 9% fat content - 80

Whole milk - 8

60% sugar syrup - 5%

Example 15: confection

To obtain chocolate prepare a mixture of cocoa liquor, soy milk dried and powdered sugar with 26% of the prescription amount of cocoa butter. Mixing is carried out at a temperature of 60oWith over 8 minutes the resulting mixture was milled on patially mill, and then mixed with the remaining amount of cocoa butter at a temperature of 50oTo achieve the viscosity of the mass 130 P. At the end of kneading add substance and flavor. The finished chocolate is directed to the manufacture of the tiles.

Components of chocolate are taken in the following ratio, wt.%: cocoa mass - 40,1; cocoa-butter - 9,1; BAS - 0,5; milk powder and 10.8; sugar - rest.

The resulting product has a taste of bitter chocolate and has a strong biological effect.

Example 16: Breads and bakery products.

The dough is prepared from 100 g of flour 1 C., 3 g of yeast baking pressed, 1.3 g of salt, 10 g of BAS, 0.08 g of citric acid, 0.04 g of acetic acid. The kneaded dough is subjected to fermentation for 30 min, cutting, proofing and baking.

The resulting product has a high organoleptic and biological indicators.

Case 17: the Oil and fat products is Gator - 0,40, dye - 0,15, flavour - 0,50), dry milk 1,0, BAS - 1,0, water - the rest, total - 100. The resulting margarine is packaged in cups made of PVC, has a fine structure with a strong milk flavor and shelf life of about 90 days at a storage temperature from 0 to +5oC.

Example 18: Mayonnaise

In the mixer in accordance with the recipe serves water at a temperature of 35-40oAnd the dry ingredients: sugar, salt, egg powder, mustard powder, baking soda, BAS. The mixture is heated to a temperature of 45-50oC and incubated for 20-25 minutes the resulting mass is cooled to 30oAnd it is injected vegetable oil and a solution of acetic or citric acid. The resulting emulsion is homogenized at a pressure of 2.0 to 5.0 MPa.

In the following ratio included in the formulation, wt.%:

Vegetable oil - 30,00-65,40

Egg powder is 0.01-4,00

The biologically active substance is 1.5-10

Mustard dry - 0,50-1,20

Sugar - 0,80-2,50

Sol - 0,1-1,6

Baking soda - 0,03-0,10

Acetic acid or lemon - 0,10-0,47

Flavorings and fillers - 0,001-50,00

Water - the Rest

The use of biologically active which improves the organoleptic and rheological properties of the final product.

High quality and biological value of the proposed mayonnaise due to the content of the biologically active substance is a protein nitrogenous compounds, carbohydrates, immune proteins, mineral salts, trace elements, and water - and fat-soluble vitamins.

Example 19: Alcoholic drink

Vodka contains: filtrate water-alcohol infusion BAS strength of 40% to 10 wt. %; aqueous-alcoholic liquid from ethyl alcohol - the rest.

The resulting vodka has a pleasant taste.

Example 20: Bezalkogolny drink

To obtain 100 liters of drink take components in the following ratio (kg): BAS 0,4; sugar 33,0; plum juice the rest.

The drink has a high biological activity, increases immunity with addiction and chronic alcoholism.

Example 21: Fish product

To obtain fish cutlets into the mixer serves the following components, kg:

Mackerel - 15

BAS - 15

The salt solution in the amount of 10 l

Spices black pepper - 1

Coriander - 0.15 g

Sugar - 0,1

Pollock - Rest

Received fish cakes subjected to freezing. The resulting product has a pleasant taste and the Ute in the following order and amounts kg:

Meat beef cutlet - 52

Meat pork - 22

The salt solution in the amount of 13.6 l

BAS - 12

Spices black pepper - 0,1

Coriander - 0.15 g

Sugar - 0,1

Stirring is carried out until a homogeneous mass. Cooked meat is subjected to grinding to the top with a hole diameter of the grating 3 mm Molded semi-frozen and Packed.

Example 23: Pasta

To get pasta for fast cooking, prepare the dough by mixing flour, salt, cuspidati additives, preservatives, BAS and fats with water, formed into semi-finished and handle it with steam, portion cut, remove moisture, cooled, Packed and Packed, in the following ratio, wt.%: flour - 75, g - 10, cuspidate supplements - 0,02, preservatives - 0,002, BAS - 1, fat - 2, water - the rest.

The resulting pasta have a high organoleptic characteristics and have a high biological activity.

Example 24: Chewing gum

Chewing gum contains: a base comprising a modified resin, plasticizer, flavouring, sweetener and BAS in the following ratio, wt.%:

BAS rosemeyer - Else

The obtained chewing gum has a pleasant taste and high biological properties.

Example 25: Beer

The method of preparation of the beverage type beer involves the following stages: mixing glucose syrup, rich in fermentable sugars and BAS, in the amount of 20% of the amount of syrup with getting songs like "wort, wort boiling with hops for flavoring, clarification, wort cooling and aeration, the introduction of yeast into the wort, fermentation of wort to convert sugar into ethanol and carbon dioxide with obtaining immature or young beer, maturation or aging fermented wort, usually through a second fermentation, filtration, pasteurization and bottling of beer.

Biologically active substance due to the content of nourishing and stimulating components has healing effects on the body of humans and mammals, therefore, obtained from petitcodiac animal bioactive compositions contain biological substances in the proportions characteristic of living organisms; it can be considered as an explanation of the beneficial effects of food, cosmetic, hygiene and pharmaceutically what>The claimed group of inventions combined to form a single inventive concept, which is aimed at ensuring that the person is necessary for the body with nutrients, due to the introduction in the diet and use of various products containing the substance.

1. Biologically active substance (BAS), characterized by the fact that it is a protein hydrolysate obtained by acid hydrolysis and subsequent neutralization peptidebased animal raw material, selected from the series: animal carcasses or fish, albumin, blood, animals or fish, meat or fish, prodeinotherium waste during the production of animals or fish, filtration to obtain a hydrolyzate and the precipitate, followed by drying the hydrolysate, with the finished product contains peptides with a molecular weight above 3000 daltons, less than 25 wt.%, optical activity20Dthe finished product is 5-15, the ratio of amine nitrogen: fatty acids: carbohydrate is(10-30):(0,2-2):(0,4-5), and it also contains sodium, chromium, Nickel, cobalt, selenium, calcium, potassium, sulfur, phosphorus, chlorine, iron, zinc, copper, manganese.

2. Biologically active food Supplement, characterized in that it contains biologically active ve is esta, mineral components, alkaloids, homeopathic remedies, glycosides, immunoglobulin preparations, phenolic compounds, organic acids, enzymes, terpenoids, hormones and hormone-like substances, cytokines, products of vegetable origin, products of microbial origin, bee products, animal products, mineraloterapiya substances of natural origin, detoxicant, technological additives, or mixtures thereof in the following ratio, wt.%:

Biologically active substance to food 10-90

Component or mixture of components Else

3. Biologically active food Supplement under item 2, wherein the carbohydrate is selected from the range: glucose, fructose, lactose, starch, sucrose, maltose, deoxyribose, soluble and insoluble dietary fiber, inulin, ribose.

4. Biologically active food Supplement under item 2, wherein the lipid is selected from the range: triglycerides, phospholipids, sterols, sterols, microbial lipids.

5. Biologically active food Supplement under item 2, wherein the vitamins are selected from a number of: vitamin a, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, Niacin, vitamin PP, the CLASS="ptx2">

6. Biologically active food Supplement under item 2, characterized in that the vitamin-like substance selected from the range of: Biotin, bioflavonoids, orotic acid, pangamic acid, paraaminobenzoic acid PABK, choline, Inositol, vitamin T, carnitine, vitamin U, lipoic acid, lipoic acid, thioctic acid.

7. Biologically active food Supplement under item 2, characterized in that the mineral components are selected from a number of: calcium, phosphorus, magnesium, sodium, potassium, sulfur, chlorine, iron, copper, selenium, iodine, chromium, zinc, fluorine, manganese, cobalt, molybdenum, silicon, bromine, silver, boron, vanadium, germanium.

8. Biologically active food Supplement under item 2, characterized in that the alkaloids selected from the range: derivatives pyrrolidine, derivatives of piperidine derivatives of pyridine, quinoline derivatives, derivatives of isoquinoline, indole derivatives, imidazole derivatives, purine derivatives, alkaloids, diterpenoid structure, steroid alkaloids, glycoalkaloids, acyclic and peptide alkaloids containing sulphur, urea derivatives.

9. Biologically active food Supplement under item 2, wherein the glycoside is selected from the range: saponins, antraglikozida, bitter glycosides, thioglycoside.

11. Biologically active food Supplement under item 2, wherein the enzyme is selected from the series: one-component enzymes, the two enzymes.

12. Biologically active food Supplement under item 2, characterized in that the terpenoids selected from the range: monoterpene and their derivatives, sesquiterpenes, diterpenes, sesquiterpene lactones, triterpene saponins, tetraterpene and their derivatives.

13. Biologically active food Supplement under item 2, characterized in that the products of vegetable origin is selected from a number of higher plants, components fractionation of higher plants, lower plants, components fractionation of lower plants.

14. Biologically active food Supplement under item 2, characterized in that the products of microbial origin selected from the range: bifidobacteria, lactobacilli, E. coli, yeast, Lactobacillus acidophilus.

15. Biologically active food Supplement under item 2, wherein the processing additives selected from a number of technological components for cabramazepine drug containing a biologically active substance (BAS), obtained under item 1, and a pharmaceutical base, selected from the series: homeopathic remedies, analgesics, sclerosant, means for correction of disorders in alcoholism, toxic and drug addiction, regenerants referenti, vegetotherapy funds hematotherapy tools, hormones and their antagonists, immunotropic tools, intermediate, neurotropic tools, organotropic means, an antimicrobial agent, a sedative, anti-cancer agents, processing AIDS, or their mixture in the following ratio, wt.%:

Biologically active substance of 0.0001-50

Pharmaceutical basis of the Rest

17. Pharmaceutical drug under item 16, characterized in that vegetotherapy means selected from the range: adrenolytic funds adrenomimeticescoe tools, cholinolytic drugs, cholinomimetics.

18. Pharmaceutical drug under item 16, characterized in that hematotherapy means selected from the range: antiplatelet agents, anticoagulants, substitutes of plasma and other blood components, fibrinolysis inhibitors, coagulants, blood coagulation factors, blood is eat, what hormones and their antagonists selected from the range: androgens, antiandrogens, glucagon and its analogues, the hormones of the hypothalamus, pituitary gonadotropins and their antagonists, thyroid hormones, their analogues and antagonists, anti-thyroid tools, insulin, corticosteroids, estrogens, gestagens, their homologues and antagonists.

20. Pharmaceutical drug under item 16, characterized in that the immunotropic means selected from a number of: immunoglobulins, immunosuppressants, immunomodulators.

21. Pharmaceutical drug under item 16, characterized in that intermediate selected from the range: adenosinergic tools, antagonists of angiotensin II receptors, AT1-subtype, histaminergic tools, diaminopimelic, prostaglandins and their antagonists, thromboxanes and their antagonists, leukotrienes and their antagonists, serotonergic tools.

22. Pharmaceutical drug under item 16, characterized in that metabolite selected from the range: anabolics, antihypoxants and antioxidants, vitamins and vitamin-like tools, hypoglycemic, synthetic and other means, lipid-lowering means, detoxifying remedies, antidotes, proofreaders metabolism of bone and cartilage tissue, macro - and microelement means for enteral and parenteral nutrition, enzymes and encipherment, means that prevent the formation and contributing to the dissolution of calculus.

23. Pharmaceutical drug under item 16, wherein the neurotropic means selected from the range: anxiolytics, sedatives and sleeping pills, antidepressants, antipsychotics and drugs lithium tonic, tonic and adaptogen, opioids and their analogues and antagonists, ANTIPARKINSONISM funds, antiepileptic drugs, psychostimulants and nootropics, means affecting neuromuscular transmission.

24. Pharmaceutical drug under item 16, characterized in that an organotropic means selected from the range: dermatotropnoe tools, gastrointestinal remedies, respiratory means, cardiovascular drugs, antispasmodics myotropic, money, regulate the function of organs of the urogenital system and reproduction.

25. Pharmaceutical drug under item 16, wherein the antimicrobial agent is selected from a range of: antibiotics, antiviral agents, antifungal agents, antimicrobial agents in combination, a synthetic antibacterial agents.

26. The pharmaceutical preparation according to p. 16 different what's antibiotics, antineoplastic hormonal drugs and hormone antagonists, antineoplastic agents of plant origin, including alkaloids.

27. Pharmaceutical drug under item 16, wherein the non-narcotic analgesics selected from the range: non-steroidal drugs, anti-inflammatory agents.

28. Pharmaceutical drug under item 16, wherein the processing additives selected from a number of technological components for tabletting, flavorings, flavoring agents, sweeteners, liquid base for suppositories, the basis for films, the basis for gels, the basis for powder, hydrophilic base, lipophilic base, devilina base, base for ointment form.

29. Biologically active additive for animal feed, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and a component selected from a number of: carbohydrates, lipids, vitamins, vitamin-like substances, minerals, alkaloids, homeopathic remedies, glycosides, immunoglobulin preparations, phenolic compounds, organic acids, enzymes, terpenoids, hormones and hormone-like substances, cytokines, products of vegetable produced in relaterade substances of natural origin, detoxicant, technological additives, or mixtures thereof in the following ratio, wt.%:

Biologically active substance 10-90

Component or mixture of components Else

30. Biologically active additive for animal feeding on p. 29, wherein the carbohydrate is selected from the range: glucose, fructose, lactose, starch, sucrose, maltose, deoxyribose, soluble and insoluble dietary fiber, inulin, ribose.

31. Biologically active additive for animal feeding on p. 29, wherein the lipid is selected from the range: triglycerides, phospholipids, sterols, sterols, microbial lipids.

32. Biologically active additive for animal feeding on p. 29, wherein the vitamins are selected from a number of: vitamin a, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, Niacin, vitamin PP, Niacin, Pantothenic acid, pyridoxine, folic acid, folacin, cyanocobalamin, vitamin C.

33. Biologically active additive for animal feeding on p. 29, characterized in that the vitamin-like substance selected from the range of: Biotin, bioflavonoids, orotic acid, pangamic acid, paraaminobenzoic acid PABK, choline, Inositol, VI active additive for animal feeding on p. 29, characterized in that the mineral components are selected from a number of: calcium, phosphorus, magnesium, sodium, potassium, sulfur, chlorine, iron, copper, selenium, iodine, chromium, zinc, fluorine, manganese, cobalt, molybdenum, silicon, bromine, silver, boron, vanadium, germanium.

35. Biologically active additive for animal feeding on p. 29, wherein said alkaloid is selected from the range: derivatives pyrrolidine, derivatives of piperidine derivatives of pyridine, quinoline derivatives, derivatives of isoquinoline, indole derivatives, imidazole derivatives, purine derivatives, alkaloids, diterpenoid structure, steroid alkaloids, glycoalkaloids, acyclic and peptide alkaloids containing sulphur, urea derivatives.

36. Biologically active additive for animal feeding on p. 29, wherein the glycoside is selected from the range: saponins, antraglikozida, bitter glycosides, thioglycoside.

37. Biologically active additive for animal feeding on p. 29, wherein the phenolic compound is selected from the series: simple phenols, penelopie, phenolic acids, coumarins, chromone, lignans, flavonoids, isoflavones, flavanone, flavones, retinoid, tannins, lignin, melanin, humic acid.

38 one-component enzymes, two enzymes.

39. Biologically active additive for animal feeding on p. 29, characterized in that the terpenoids selected from the range: monoterpene and their derivatives, sesquiterpenes, diterpenes, sesquiterpene lactones, triterpene saponins, tetraterpene and their derivatives.

40. Biologically active additive for animal feeding on p. 29, characterized in that the products of vegetable origin is selected from a number of higher plants, components fractionation of higher plants, lower plants, components fractionation of lower plants.

41. Biologically active additive for animal feeding on p. 29, characterized in that the products of microbial origin selected from the range: bifidobacteria, lactobacilli, E. coli, yeast, Lactobacillus acidophilus.

42. Biologically active additive for animal feeding on p. 29, wherein the processing additives selected from a number of technological components for tabletting, food additives, flavors, sweeteners, preservatives, dyes, liquid.

43. Veterinary drug, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and pharmace the funds means for correcting disorders in alcoholism, toxic and drug addiction, regenerants referenti, vegetotherapy funds hematotherapy tools, hormones and their antagonists, immunotropic tools, intermediate, neurotropic tools, organotropic means, an antimicrobial agent, a sedative, anti-cancer agents, processing AIDS, or their mixture in the following ratio, wt.%:

Biologically active substance of 0.0001-50

Pharmaceutical basis of the Rest

44. Veterinary drug under item 43, wherein vegetotherapy means selected from the range: adrenolytic funds adrenomimeticescoe tools, cholinolytic drugs, cholinomimetics.

45. Veterinary drug under item 43, wherein hematotherapy means selected from the range: antiplatelet agents, anticoagulants, substitutes of plasma and other blood components, fibrinolysis inhibitors, coagulants, blood coagulation factors, hemostatic, stimulators of hematopoiesis, fibrinolitiki.

46. Veterinary drug for p. 43, characterized in that the hormones and their antagonists selected from the range: androgens, antiandrogens, glucagon and its analogues, honesty, antithyroid tools, insulin, corticosteroids, estrogens, gestagens, their homologues and antagonists.

47. Veterinary drug under item 43, wherein the immunotropic means selected from a number of: immunoglobulins, immunosuppressants, immunomodulators.

48. Veterinary drug under item 43, wherein intermediate selected from the range: adenosinergic tools, antagonists of angiotensin II receptors, AT1-subtype, histaminergic tools, diaminopimelic, prostaglandins and their antagonists, thromboxanes and their antagonists, leukotrienes and their antagonists, serotonergic tools.

49. Veterinary drug under item 43, wherein metabolite selected from the range: anabolics, antihypoxants and antioxidants, vitamins and vitamin-like tools, synthetic hypoglycemic and other means, lipid-lowering means, detoxifying remedies, antidotes, proofreaders metabolism of bone and cartilage tissue, macro - and microelements, rehydralyte, regulators of water and electrolyte balance and KHS., tools affecting uric acid metabolism, means for enteral and parenteral nutrition, enzymes and encipherment, means preventing obrazovanie neurotropic means selected from the range: anxiolytics, sedatives and sleeping pills, antidepressants, antipsychotics and drugs lithium tonic, tonic and adaptogen, opioids and their analogues and antagonists, ANTIPARKINSONISM funds, antiepileptic drugs, psychostimulants and nootropics, means affecting neuromuscular transmission.

51. Veterinary drug under item 43, wherein the organotropic means selected from the range: dermatotropnoe tools, gastrointestinal remedies, respiratory means, cardiovascular drugs, antispasmodics myotropic, money, regulate the function of organs of the urogenital system and reproduction.

52. Veterinary drug under item 43, wherein the antimicrobial agent is selected from a range of: antibiotics, antiviral agents, antifungal agents, antimicrobial agents in combination, a synthetic antibacterial agents.

53. Veterinary drug under item 43, wherein the anti-cancer agents selected from the range: alkylating tools, antimetabolites, antitumor antibiotics, antineoplastic hormonal drugs and hormone antagonists, antineoplastic agents of plant origin is algetic selected from the range: non-steroidal drugs, anti-inflammatory agents.

55. Veterinary drug under item 43, wherein the processing additives selected from a number of technological components for tabletting, flavorings, flavoring agents, sweeteners, liquid base for suppositories, the basis for gels, the basis for films, the basis for powder, hydrophilic base, lipophilic base, devilina base, base for ointment form.

56. Fertilizer, characterized in that a represents a residue obtained by p. 1.

57. Activator microbiological processes, plant growth and plant cells, characterized by the fact that is a solution of biologically active substances (BAS), obtained under item 1, with a concentration of 110-1-110-12.

58. Oral nutrition, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and the food is acceptable based on the following ratio of components, wt.%:

The biologically active substance is 0.001-50

Food acceptable basis for the Rest

59. Perfume and cosmetic, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and PA is ve, the module is based on the emulsion, the module on the base gel, the module on aqueous-alcoholic basis, in the following ratio, wt.%:

Biologically active substance 20

Perfume and cosmetic basis of the Rest

60. Hygienic means, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and hygienically acceptable basis for external use, selected from the series: module for toothpaste, a module for shampoo, module for liquid soap, a module for soap, foaming basis, in the following ratio, wt.%:

Biologically active substance To 25

Hygienically acceptable basis for the Rest

61. Dairy product, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and dairy basis, selected from the range: a dairy unit, curd module, dairy module, in the following ratio, wt.%:

Biologically active substance To 25

Lactic basis of the Rest

62. Confection, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and the basis chosen ADCI, module for chocolate, module for Oriental sweets, module for sherbet, in the following ratio, wt.%:

Biologically active substance To 25

The basis of the Rest

63. Bakery product, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and a base selected from the series: module for gingerbread, the module for cakes, module for biscuits, module wafer, module for bread, module for bakery products in the following ratio, wt.%:

Biologically active substance To 40

The basis of the Rest

64. Oil and fat product, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and a base selected from the range: margarine, butter, vegetable oil, combined oil, butter substitute, fat, in the following ratio, wt.%:

Biologically active substance To 15

The basis of the Rest

65. Sauce, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and the basis chosen from a number of: a module for mayonnaise, module for ketchup, the module for dressing, module adzhika, soy mi active substance To 25

The basis of the Rest

66. Alcoholic beverage, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and the aqueous-alcoholic basis in the following ratio, wt.%:

Biologically active substance To 35

Water-alcohol base the Rest

67. Soft drink, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and a base selected from the range: drinking water, mineral water, mineral water, juice, nectar, juice, lemonade, non-alcoholic beer, kvass, in the following ratio, wt.%:

Biologically active substance To 15

The basis of the Rest

68. Fish product, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and fish based on the following ratio, wt.%:

Biologically active substance To 40

Fish the basis of the Rest

69. Meat product, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and the basis chosen from a number of: a module for boiled sausages, module boiled-smoked sausages, module Procope module for wieners, in the following ratio, wt.%:

Biologically active substance To 40

The basis of the Rest

70. Pasta, characterized by the fact that they contain biologically active substance (BAS), obtained under item 1, and a test basis in the following ratio, wt.%:

Biologically active substance To 35

Test the basis of the Rest

71. Chewing gum, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and the module for chewing gum in the following ratio, wt.%:

Biologically active substance To 25

Module for chewing gum the Rest

72. Beer, characterized in that it contains a biologically active substance (BAS), obtained under item 1, and beer basis in the following ratio, wt.%:

Biologically active substance To 40

Beer basis of the Rest

 

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