Method and device for non-invasive detection of medical conditions due to the current control peripheral arterial tone

 

The invention relates to medicine, namely to a method and apparatus for non-invasive detection of physiological status or medical condition. The method provides detection of such status, or status as myocardial ischemia or attack sleep apnea, due to the detection of the response of peripheral arterial tone on this status or condition. Around the distal part of the finger of the patient create a field of static pressure. Make detection of changes in the peripheral arterial tone and related to volume changes in the distal part of the finger in order to identify the physiological status or medical condition, or to monitor them. The device includes a finger sensor in the form of a tube to enter the finger of a patient, which is designed for the application of pressure, and connecting the cuff pressure for expanding the boundaries of the specified pressure field. Finger sensor or includes a signal sensor/transducer, or combined with them. The invention allows to simplify the means of non-invasive techniques for the detection of ischemia of the heart as a consequence of a lesion of the coronary artery. 10 S. and 47 C.p. f-crystals, 39 ill.

Those who>. The method is non-invasive detection of changes in the physiological state of the patient, namely, that carry out ongoing monitoring of peripheral arterial tone and specific change judge him about the change in the physiological state of the patient, and control peripheral arterial tone is carried out by measuring changes in at least one hemodynamic parameters.

2. The method according to p. 1, characterized in that the physiological condition is either ischemia of the myocardium, or the beginning stage of sleep with rapid eye movement (REM) or attack sleep apnea.

3. The method according to p. 1, characterized in that it further includes the operation of application of pressure to the measuring from about 30 mm RT. Art. to a value greater by about 10% of the diastolic pressure of the patient, and this pressure is sufficient to prevent the accumulation of venous blood in the specified location measurement and uncontrolled venous return blood in this place, as well as for partial unloading stresses in the wall of arteries, but without overlap, and place of measurement, when it is at heart level or below.

4. The method according to p. 1, characterized in that scroll changes in blood flow of the arteries of the skin.

5. The method according to p. 1, characterized in that the operation of the current control changes in the peripheral arterial tone provides ongoing monitoring of changes in blood flow of the arteries of the finger or toe.

6. The method according to p. 1, characterized in that the current control is carried out continuously and/or in real time.

7. The device to detect changes in the physiological state of the patient, characterized in that it includes a finger sensor for application to a finger or leg of the patient, designed to measure changes at least one hemodynamic parameter determining peripheral arterial tone, and a processor configured to receive signals from the sensor and generate an output signal reflecting changes in peripheral arterial tone in the specified finger to determine the physiological status or medical condition of the patient.

8. The device according to p. 7, characterized in that the finger sensor includes a membrane for the application of pressure sufficient to prevent the accumulation of venous blood in the specified finger and partial discharge voltage in the wall of the arteries in the specified finger is for monitoring changes in blood volume in the specified finger.

10. The device according to p. 9, characterized in that the finger sensor further comprises a cuff for expansion of the field of application of pressure to the finger.

11. The device under item 8, wherein the finger sensor is configured to control the peripheral arterial tone continuously and/or in real time.

12. The device application of pressure to the finger or leg of the patient during non-invasive detection of changes in the physiological state of the patient, characterized in that it includes a rigid cylindrical shell having an open end and a closed end, the closed one end of the tubular membrane placed inside this shell, and the open end of the membrane is sealed to the open end of the shell, and located so that the chamber formed between the closed end of the shell and the membrane, connected to the pressure source providing a pressure on the membrane and through it on his finger, and means to prevent the expulsion of the tubular membrane of a cylindrical shell under the application of pressure from the pressure source.

13. The method is non-invasive detection of physiological dysfunction of the patient, characterized in that carciente, including and around the distal tip of the finger, where the field static pressure sufficient to prevent mainly the accumulation of venous blood in the specified distal end, preventing mainly uncontrolled venous return blood flow in the specified distal end, and a partial discharge voltage in the wall of the arteries in the specified distal end, but without overlap, when the distal end is at heart level or below, and the measurement of changes in blood volume or other hemodynamic parameter specified in the distal end of the accompanying arterial pulse wave.

14. The method according to p. 13, characterized in that the measurement of blood volume or other hemodynamic parameter is carried out by measuring changes in the volume specified the distal end of the finger.

15. The method according to p. 13, characterized in that the measurement of changes in blood volume or other hemodynamic parameter is carried out by measurement of optical density changes specified the distal end of the finger.

16. The method according to one of paragraphs.13-15, characterized in that the current control these changes are to detect the existence of myocardial ischemia in a patient.

17. The method according to one of the least either of beginning and duration of sleep stages rapid eye movement (REM), either attack sleep apnea.

18. The method according to one of paragraphs.13-15, characterized in that the specified static pressure is in the range from 30 mm RT. Art. to a pressure of approximately 10% higher diastolic pressure of the patient.

19. The method according to one of paragraphs.13-15, characterized in that the static pressure is 70 mm RT. Art.

20. The method according to one of paragraphs.13-15, characterized in that the specified static pressure is applied around the area proximal to the extreme tip of the finger, including the specified point.

21. The method according to p. 20, characterized in that the specified static pressure is applied through the device under item 12.

22. The device application of pressure to the finger or leg of the patient during non-invasive detection of the physiological state of the patient, characterized in that it includes a rigid cylindrical shell having an open end and a closed end, one or more membranes placed inside the shell and the open end of the membrane is sealed to the open end of the shell, and between the closed end of the shell and the membrane formed by the camera that is connected to a pressure source providing a pressure on the membrane and through memb is the with the specified cap shaped the application of pressure on the opposite side of the distal part of the finger, to prevent the accumulation of venous blood in the specified finger, to prevent the expulsion of the specified tubular membrane from the specified cap during the application of pressure from the pressure source and to prevent displacement of the specified shell relative to the finger adjacent to the specified shell ring cuff in the form of a cylindrical sleeve attached to the elastic membrane, and this membrane and the inner wall of the specified sleeve form a cavity associated with the source of pressure to compress the membrane to the finger to extend the field of application of pressure to the finger.

23. The device according to p. 22, characterized in that it further includes a heating mechanism.

24. The device according to p. 23, characterized in that it further comprises a vertical displacement sensor device relative to the heart.

25. The device according to p. 22, characterized in that the membrane is divided into two sections at two diametrically opposite sides of the finger.

26. The device according to p. 22, characterized in that the cap is divided into many sections, the NENO together to form a specified cap.

27. The device under item 26, characterized in that the means of preventing ejection of the specified membrane represents a bounding edge attached to the shell and having a middle section, inserted into the tubular membrane to limit internal axial displacement of the membrane.

28. The device application of pressure to the finger or leg of the patient during non-invasive detection of changes in the physiological state of the patient, characterized in that it includes a rigid shell having an open end and a closed end, an elastic membrane is placed inside this shell and hermetically connected with the open end of the specified shell, an annular strip of pressure application, provided inside this shell and located with the possibility of clamping the specified membrane to the inner wall of the specified shell, U-shaped bounding rib provided inside this shell with the ability of the clamp to the specified membrane, so to prevent axial shift of the membrane in order to avoid pushing placed in her fingers.

29. The device according to p. 28, characterized in that the specified tape application pressure divides the membrane into two sealed cameracase tool of pressure application, which includes a tubular socket for input on the specified length of the distal end of the finger or leg of the patient, including the distal tip of the finger, the pressure source for the application fields of static pressure around the distal end of the finger, including the distal tip of the finger or leg of the patient, when he entered into the specified tubular socket, and a measuring device for measuring changes in blood volume or other hemodynamic parameter specified in the distal end of the finger.

31. The device according to p. 30, characterized in that the measuring device is arranged to measure changes in the volume specified the distal end of the finger associated with waves of blood pressure.

32. The device according to p. 30, characterized in that the measuring device is arranged to measure changes in optical density specified in the distal end of the finger associated with waves of blood pressure.

33. Device according to one of paragraphs.30 to 32, characterized in that the said means of pressure application is performed with application of static pressure around the distal end of the finger, and this field is elongated in the proxy the measurements of such changes.

34. Device according to one of paragraphs.30 to 32, characterized in that the said means of pressure application includes a casing installed in her deformable tubular membrane, limiting the tubular chamber in said shell, and a pressure source for its application to the said tubular chamber to create a deformation of the tubular membrane in accordance with changes in the volume of blood flow through put in it a finger of the patient, and the specified deformable tubular membrane is divided into several sections.

35. The device according to p. 34, characterized in that the deformable tubular membrane is divided into two sections at diametrically opposite sides entered into the finger of the patient.

36. The device according to p. 34, characterized in that the shell is divided into many sections, one for each of the sections of the membrane, combined together for the formation of this outer tubular chamber together with the specified sections of the membrane.

37. The device according to p. 34, characterized in that the tubular membrane is divided into many sections by using the bounding edges attached to the shell and having a middle section, inserted into the tubular membrane, so that the Oh tubular chamber.

38. The device according to p. 30, characterized in that the pressure applied to the specified source pressure is in the range from 30 mm RT. century to approximately 70 mm RT. Art.

39. The device according to p. 30, characterized in that the pressure applied is specified by means of application of pressure is 70 mm RT. Art.

40. The device according to p. 30, characterized in that it additionally includes a Converter to convert these measured changes in said end of the finger arterial blood pressure of the patient.

41. The device according to p. 40, characterized in that the Converter comprises a measuring device for measuring the hydrostatic pressure is added to the blood pressure of the patient during vertical movement of the finger of the patient in each of the many vertical positions relative to the level of the patient's heart, and the computing device using the specified field of the static pressure and the measured hydrostatic pressure for calibration of the measured changes at the end of the finger of the patient in the values of the arterial blood pressure of the patient and to convert these measured changes in arterial blood pressure.

42. Ustroystvo patient to a predetermined temperature, in order to maximize arterial blood vessels in the finger.

43. The device according to p. 30, characterized in that the pressure source is embedded in at least one finger of a glove worn by the patient and designed to measure changes in the distal end of the finger of the patient is entered into the finger gloves.

44. Device for monitoring hemodynamic status of the patient, characterized in that it includes a tubular socket to enter the distal end of the finger of the patient, the heater in the specified slot to heat the distal end of the finger of the patient to a predetermined temperature in order to maximize arterial blood vessels in the specified finger, and a measuring device for measuring changes in blood volume or other hemodynamic parameter at the distal end of the finger, accompanying waves of blood pressure.

45. The device according to p. 44, wherein the specified slot additionally includes means application of static pressure around the distal end of the finger is sufficient to prevent the accumulation of venous blood and for partial unloading stresses in the wall of the arteries of the finger, but without overlap, when the finger is N. the STV made with the possibility of measuring changes in the volume specified in the distal part of the finger, accompanying waves of blood pressure.

47. Device according to one of p. 44 or 45, characterized in that the measuring device is arranged to measure changes in optical density specified in the distal part of the finger.

48. Device for the detection of cardiological distress of the patient, characterized in that it includes a means of pressure application, which includes a tubular socket for input on the specified length of the distal end of the finger or leg of the patient, including the distal tip of the finger, the pressure source for the application fields of static pressure around the distal ring finger when he entered in the specified tubular socket, and the specified static pressure is sufficient to prevent the accumulation of venous blood in the distal end of the finger and for partial unloading stresses in the wall of arteries, but without overlap, in the specified finger with its location at the heart level, measuring device for measuring changes in blood volume or other hemodynamic parameter at the distal end of the finger, accompanying waves of blood pressure, and an indicator to provide indication of the existence of cardial the cent compared to known normal condition of the patient without the presence of cardiological distress.

49. Device for monitoring the sleep state of the patient, characterized in that it includes a means of pressure application, which includes a tubular socket for input on the specified length of the distal end of the finger or leg of the patient, including the distal tip of the finger, the pressure source for the application fields of static pressure around the distal end of the finger when he entered in the specified tubular socket, and the specified static pressure is sufficient to prevent, in General, the accumulation of venous blood in the distal end of the finger and for partial unloading stresses in the wall of arteries, but without overlap, in that finger when he is at heart level, measuring device for measuring changes in blood volume or other hemodynamic parameter at the distal end of the finger associated with the waves, blood pressure, and an indicator to provide indication of the sleep state of the patient based on the measured changes of hemodynamic parameters.

50. Device according to one of p. 48 or 49, characterized in that the measuring device is arranged to measure changes in the volume of the specified end Panino with the possibility of measuring changes in optical density of the specified end of the finger.

52. Device according to one of p. 48 or 49, characterized in that the pressure applied is specified by means of application of pressure is in the range from 30 mm RT. Art. to 70 mm RT. Art.

53. Device according to one of p. 48 or 49, characterized in that the said means of pressure application is performed with application of static pressure around the distal end of the finger, where the field static pressure is expanded in the direction of the patient's heart at a certain distance from the place in which to measure such changes.

54. Device according to one of p. 48 or 49, characterized in that the said means of pressure application contains a shell installed in her deformable tubular membrane bounding together with the specified outer shell of the tubular chamber, and the inner tubular socket to enter him in the distal end of the finger of the patient, and the specified pressure source is made with the possibility of application fields static pressure to the specified external tubular chamber to create a deformation of the tubular membrane in accordance with changes in the volume injected in it the finger of a patient associated with waves of blood pressure, with the specified deformiruemym each section has a Central region and an outer periphery, the external periphery of each section is limited relative displacement inside, so that the pressure within the outer tubular camera moves inside the Central area of each section of the membrane to a greater degree than its outer periphery to provide a tight clamping finger of the patient in the device and exceptions axial and rotary movement of the device relative to the body's extremities when shifting into the Central areas of many sections of the membrane.

55. The device according to p. 54, characterized in that the deformable tubular membrane is divided into two sections at two diametrically opposite sides put in her finger.

56. The device according to p. 54, characterized in that the shell is divided into many sections, one for each of the sections of the membrane, combined together for the formation of this outer tubular chamber together with the specified sections of the membrane, and each of the sections of the membrane are quadrilateral membrane attached at its peripheral edges to the peripheral edges of its corresponding section of the shell.

57. The device according to p. 54, characterized in that the tubular membrane is divided into many sections by using granitic to limit the offset inside the outer periphery of each section of the membrane during the application of the specified pressure to the said tubular chamber.

Priority items:

30.01.1997 on PP.1, 4-6, 11, 16, and 48;

30.07.1996 on PP.7-10, 12-15, 20-27, 30-36, 40-42, 44-47, 49-51 and 53-57;

21.05.1997 on PP.2-3, 17-19, 28-29, 37-39, 43, 52.

 

Same patents:

The invention relates to medicine, neonatology

The invention relates to medicine, cardiology

The invention relates to medicine, namely, neurology, neurosurgery, manual therapy, traumatology, orthopedics, obstetrics, gynecology, and is intended for diagnostics development of piriformis syndrome
The invention relates to the field of medicine, particularly cardiology

The invention relates to medicine, in particular to electrocardiography

The invention relates to medicine and can be used as an effective method of increasing human efficiency by preventing the fatigue of students, in particular, in the preparation and training in using computers

The invention relates to medicine, namely to traumatology and is intended for the diagnosis of suppurative inflammation of the soft tissues in the treatment apparatus of external fixation external fixation

The invention relates to medical equipment, namely, devices for measuring intracranial pressure non-invasive method using ultrasonic Doppler device which measures the speed of blood flow within the ophthalmic artery as in intracranial and veneciano area of the ophthalmic artery

The invention relates to medicine, namely to measure parameters of cardiovascular system

FIELD: medicine.

SUBSTANCE: method involves recording heart beat rate and systolic arterial blood pressure before and after two-stage exercise stress. The first stage is of 50 W within 3 min and the second one is of 75 W during 2 min. Patient rest pause is available between loading stages to recover initial heart beat rate. Prognostic estimation of cardiopulmonary complications is carried out with mathematical formula applied.

EFFECT: reduced risk of complications in performing tests.

FIELD: medicine.

SUBSTANCE: method involves measuring cardio- and hemodynamic values, calculating estimates of the values and displaying the estimates on monitor. Measuring and calculating each cardio- and hemodynamic value is carried out during basic periods of their oscillations corresponding to heart contraction cycle and respiratory cycle related to absolute time.

EFFECT: high accuracy of estimation.

4 dwg, 1 tbl

FIELD: animal science.

SUBSTANCE: the present innovation deals with dynamic loading onto cardio-vascular system in animals. Selection should be carried out by the following parameters: , ΔT3 and Δn, where ΔT1 - the time for pulse increase at running, ΔT2 - the time for pulse stabilization after running, ΔT3 - the time for pulse increase after running, Δn - the increase of pulse frequency after running. One should select animals into milking herd at the following values; ΔT3 ≤ 10 sec, Δn ≤ 10 beats/min. The method enables to present perspective evaluation of lactation capacity in animals.

EFFECT: higher efficiency of selection.

1 dwg, 1 ex, 1 tbl

FIELD: medicine.

SUBSTANCE: method involves recording rheogram from feet and legs lifted and fixed at an angle of 45є. Then, rheogram is recorded on inhaling from legs directed vertically downward. Functional blood circulation reserve index is calculated as product of results of dividing and subtracting rheographic indices recorded under conditions of lifted and lowered extremities that means under conditions of functional venous system relief and venous hypertension, respectively.

EFFECT: enhanced effectiveness in recognizing patient group suffering from severe lower extremities ischemia.

6 dwg

FIELD: medicine.

SUBSTANCE: method involves recording rheogram from feet and legs lifted and fixed at an angle of 45є. Then, rheogram is recorded on inhaling from legs directed vertically downward. Functional blood circulation reserve index is calculated as product of results of dividing and subtracting rheographic indices recorded under conditions of lifted and lowered extremities that means under conditions of functional venous system relief and venous hypertension, respectively.

EFFECT: enhanced effectiveness in recognizing patient group suffering from severe lower extremities ischemia.

6 dwg

FIELD: medicine.

SUBSTANCE: method involves applying a set of reference values like body mass, arterial blood pressure, pulse rate in rest state and general physical condition values. Exercise stress is sequentially applied for evaluating vertebral column flexibility, response quickness, dynamic leg force, speed-and-force tolerance. Each value is compared to a reference value, the differences of each item between reference and actual values are summed and the total value is interpreted in terms of complex human physical condition.

EFFECT: high reliability of the method; simplified testing process requiring no complex and expensive equipment and high skill personnel.

6 cl

FIELD: medicine.

SUBSTANCE: method involves applying a set of reference values like body mass, arterial blood pressure, pulse rate in rest state and general physical condition values. Exercise stress is sequentially applied for evaluating vertebral column flexibility, response quickness, dynamic leg force, speed-and-force tolerance. Each value is compared to a reference value, the differences of each item between reference and actual values are summed and the total value is interpreted in terms of complex human physical condition.

EFFECT: high reliability of the method; simplified testing process requiring no complex and expensive equipment and high skill personnel.

6 cl

FIELD: medicine, juvenile clinical nephrology.

SUBSTANCE: disease duration in case of obstructive pyelonephritis should be detected by two ways: either by detecting the value of NADPH-diaphorase activity, as the marker of nitroxide synthase activity in different renal department and comparing it to established norm, or by detecting clinico-laboratory values, such as: hemoglobin, leukocytes, eosinophils, urea, beta-lipoproteides, lymphocytes, neutrophils, the level of glomerular filtration, that of canalicular reabsorption, urinary specific weight, daily excretion of oxalates, arterial pressure, and estimating their deviation against average statistical values by taking into account a child's age.

EFFECT: higher efficiency of detection.

7 dwg, 1 ex, 6 tbl

FIELD: medicine, neurosurgery.

SUBSTANCE: one should measure blood pressure in afferent vessel of cerebral arteriovenous malformation (AVM). If measured pressure is above that of functionally insignificant vessel being 25% against systemic arterial pressure for AVM at blood flow of 1000 ml/min and 50% for AVM at blood flow of 500 ml/min one should conclude the vessel to be functionally valuable. The method enables to decrease complications due to increased reliability in detecting functional value of ABM-supplying vessels.

EFFECT: higher efficiency of detection.

1 ex

FIELD: medicine, cardiology.

SUBSTANCE: in male patients of elderly and senile age one should register electrocardiogram and its first derivative in 12 leads to evaluate the rate of ventricular activation. In case of this rate being below 34.9 one should evaluate high degree of lethality risk. The method enables to detect the risk for availability of complex cardiac rhythmic disorders more rapidly and non invasively in case of exacerbation of bronchoobstructive diseases.

EFFECT: higher efficiency of diagnostics.

4 ex, 1 tbl

Up!