A method for the diagnosis of ischemic damage to the heart muscle
The invention relates to medicine, cardiology. Patients continuously, long-term ECG record. Analyzing the deviation from the contour points of the beginning and end of electroneutral plot repolarization curve. The absolute values of the deviations of these points in mV of each cardiac contraction is multiplied by a coefficient snapshot conductivity (k). k is calculated as the ratio 1mV to the magnitude of the amplitude of the RS of the same cardiac cycle. Certain torregiani values of the analyzed points diagnose ischemic damage to the heart muscle. The method allows to diagnose myocardial ischemia taking into account the physiological and external changes. 3 Il. The invention relates to medicine, namely to methods electrocardiographic diagnosis and assess the degree of ischemic damage to the heart muscle.A known method for the diagnosis of ischemic damage to the heart muscle, which is performed through a continuous, for example, the daily record ECG in real time and its memorization and subsequent playback by assessing the deviation from the contour of the pixel values of j and i, the beginning and end of electrometer is a 61 In 5/0468, 26.01.1993.At that, the registered potential on the body surface is formed as the sum of the mutual influences active intracardiac current sources and changes of intracellular potentials, low ongoing area of heterogeneous structure of the lungs, high muscle conducted education and the influence of the surface section of the body of air in a specific point of attachment of the electrodes and additional sources of errors introduced hardware, which is expressed in limited frequency bands of the transmission amplifier and insufficient sample rates and bit depth than do not take into account temporary daily biological cycle and the full range of physiological and phenotypic changes during registration cardiomegaly.As a result, in the conventional method of diagnosis at check cardiomegaly changes the amplitude as high-gradient components of the PQRST complex, and low-amplitude plots of cardiomegaly. Therefore, the amplitude value of a particular point of the PQRST complex for the foregoing reasons, it may be a variable value.The use of standard calibration pulse is equal to 1mV, you can compare the amplitude value of electrocardiograms, i registered, - points at the beginning and end electrically neutral site repolarization curve complex RST the ST segment of the electrocardiogram, diagnose ischemic damage to the heart muscle, not taking into account the amplitude of the oscillations. Thereby by a known method to accurately judge ischemic damage to the heart muscle is not possible, since only the absolute value of cardiomegaly without regard to their level and all sums hardware, physiological and phenotypic changes during its registration.The basis of the invention is to provide a method of diagnosis of ischemic damage to the heart muscle, which would take into account all contributions hardware, physiological and external changes during registration cardiomegaly by using the correction coefficient k than would have increased the accuracy of diagnosis of ischemic damage.This task is solved in that in the known method for the diagnosis of ischemic damage to the heart muscle, which is performed through a continuous, for example, the daily record ECG in real time and its memorization and subsequent playback capability, by assessing deviations of amplexa RST the ST segment of the electrocardiogram, according to the invention the recorded absolute values in mV deviations from the contour points j and i each cardiac contraction corrects by multiplying by a factor of torque conductivity k, is equal to the ratio 1mV to the magnitude of the amplitude of the RS in mV of the same heart beat, and when torregiani the pixel values of j and i +0,20 mV, in the case of elevation of the ST segment, and more -0,10 mV, in the case of ST-segment depression, diagnosed ischemic damage to the heart muscle.Thus, using the adjustment factor torque conductivity k, is equal to the ratio 1mV to the magnitude of the amplitude of the RS in mV of each individual heart beat, and multiplying by him absolute value reported in mV deviations of the points j and i of the ST segment from the contours obtained torregiani values of deviations from the contours of these points, considering that for each heartbeat of the value of the coefficient k is a value of its own and takes into account the whole amount of time, surface, spatial, and electrical events of the heart, and whose values are already diagnosed ischemic damage to the heart muscle.In the following the invention is illustrated by the example of his particular job and drawings, in which: Fig.1 pokarekare one patient presented a number of amplitude values in a single heart beat, taken at different times of the daily record; Fig. 2 shows the same graph with the adjusted amplitude values of the deviations and images the same heart rate, are presented in absolute and adjusted; Fig. 3 shows the amplitude values of the deviations recorded for the three patients with different anatomical structure of the body, where next to each heart contraction shows the absolute and adjusted in this way the values of the deviations from the contour points j and i.The method is as follows.In this particular case portable cardioregulatory with Autonomous power source are recording the electrocardiogram during the day. After conducting such recordings make a reset of the recorded electrocardiogram on your computer's hard drive in a pre-prepared map of the patient for subsequent playback and analysis.Diagnosis of ischemic damage to the heart muscle is produced by evaluating the deviation from the contour of the pixel values of j and i, the beginning and end of electroneutral plot repolarization curve of the RST complex ST segment of each cardiac contraction recorded electrocardiogram.Health the ST segment, namely, the deviation from the contour of the pixel values of j and i, the beginning and end of electroneutral plot repolarization of the heart muscle, ranging from -0,10 mV to +0,20 mV.As seen on electrocardiograms one cardiac contraction, shown in Fig.1, the absolute values of the deviations from the contour points j and i of the ST segment at different times of the day will be different, and for fragment 5 is logged ischemic damage to the heart muscle.Therefore, according to the invention, the recorded absolute values in mV deviations of the points j and i of the ST segment from the contour of each of the RST complex of the electrocardiogram shown in Fig.1, taken into account for the diagnosis only after correction by multiplying these values by the correction factor torque conductivity k=1mV/ARSwhere; ARS- amplitude plot for RS accrued heart of the complex is expressed in mV.And already on the adjusted values of the deviations of the points j and i, shown in Fig.2, it is seen that for fragment 5 ischemic damage to the heart muscle is not confirmed.In the case of multiple patients with different anatomical structure of the body by multiplying the absolute deviations from the contour points j and i, equal -0,10 and -0,09 mV, coefficient and deviation +0.01 and +0,10 mV by a factor of k=0.75 to for the third patient, obtain the total deviation from the contour points j and i, equal -0,03 -0,02 and mV, +0,03 +0,05 mV and +0,007 +0,075 mV, for the third patient, as shown on the electrocardiogram of Fig.3, indicating the absence of the ischemic lesion of the cardiac muscle in all patients. While taking into account their absolute values, without taking into account the correction factor torque conductivity k, 'd have to say ischemic damage to the heart muscle in the first patient.Thus, accounting for the whole range of physiological and phenotypic changes during registration cardiomegaly, through the use of the correction factor torque conductivity k, increases the reliability of the diagnosis of ischemic damage of the heart muscle in various real conditions of registration of the electrocardiogram.In addition, development on this way for each cardiographic lead tolerance will lead to a total system standardized assessments, will allow you to operate on shared values in the interpretation of coronary heart disease, to quantify the magnitude of ischemic damage to the heart muscle.
Formularizing long-term recording of the electrocardiogram in real time and its memorization and subsequent playback by assessing deviations from the contour of the pixel values of j and i - the beginning and end of electroneutral plot repolarization curve of the RST complex ST segment of the electrocardiogram, characterized in that the recorded absolute values in mV deviations from the contour points j and i each cardiac contraction corrects by multiplying by a factor of instantaneous conductance, equal to the ratio 1mV to the magnitude of the amplitude of the RS in mV of the same heart beat, and when torregiani the pixel values of j and i +0,20 mV in the case of elevation of the ST segment, and more -0,10 mV in the case of ST-segment depression, diagnosed ischemic damage to the heart muscle.
FIELD: medicine, cardiology.
SUBSTANCE: one should register rhythmocardiogram, measure current total power in low-frequency and high-frequency areas of dynamic row of cardiointervals. Evaluation of psychophysiological state should be performed by the value of stress index S calculated due to original mathematical formula by taking into account the power of low-frequency and high-frequency constituents of the range of dynamic row of cardiointervals. In case of standard conditions of measurement - the rest lying at one's back position the value of S stress index should be considered to be equal to 1. The method enables to rapidly and noninvasively detect and range human psychophysiological state.
EFFECT: higher accuracy of evaluation.
2 dwg, 1 ex, 2 tbl
SUBSTANCE: method involves estimating vegetative tonus using cardiointervalography approach and its medication adjustment under cardiointervalography control. The cardiointervalography examination is carried out before applying treatment, in the course of and after the treatment. Each time vegetative tonus increment is estimated on the basis of voltage index. When applying medication adjustment, nootrop group preparations are used that are selected before applying treatment with initial vegetative tonus disorder distinguished by vagotonia or sympathicotonia being taken into account. Preparation or combination of preparations or their doses and application duration is adjusted on basis of vegetative status direction changes obtained from cardiointervalography examination data. The treatment is continued until vegetative status direction change stops towards normotonia.
EFFECT: enhanced effectiveness in selecting individual treatment course.
3 cl, 3 dwg
SUBSTANCE: method involves recording rhythmocardiogram. Then, spectral analysis of RR intervalogram components in frequency bandwidth from 0.04 to 0.4 Hz is carried out and information value Z is determined from formula Z=Ahf/Alf, where Ahf is the maximum of high frequency component in bandwidth from 0.14 to 0.4 Hz, Alf is the minimum of high frequency component in bandwidth from 0.04 to 0.14 Hz. Z value being greater than 45 and lower than 14, persons consuming narcotic drugs are detected. Z value being lower than 14, persons consuming sedative drugs like opium, morphine, heroine are detected. Z value being greater than 45, persons consuming psychostimulating drugs like cocaine, amphetamine, efedrone, sydnocarb are detected.
EFFECT: high reliability of screening study data.
4 cl, 6 dwg
FIELD: medicine, diagnostics.
SUBSTANCE: the method deals with monitoring the difference in signals obtained from N pickup units, where N ≥ 2, ECG, pulse, temperature and analysis of the range and variability of their rhythms, nonlinear chaotic fluctuations during the period of registration. During analysis one should detect the values for fractal dimensions of Hirst's index and informational Fischer's index standardized, correspondingly, by the average value during either nocturnal or diurnal period. One should conclude upon improved body state by the normalization of signals' difference of peridiurnal rhythm, increased fractal dimensions, Hirst's index, decreased standardized informational Fischer's index, and one should conclude upon worse physiological or pathophysiological processes according to the opposite alterations. The method enables to widen functional possibilities during diagnostics.
EFFECT: higher accuracy of diagnostics.
3 dwg, 6 ex
FIELD: medicine; cardiology.
SUBSTANCE: electrocardiogram of patients with arterial hypertension is subject to twenty-four-hours monitoring. Spectral analysis of variability of heart beating is conducted and low-frequency, very low frequency and high frequency wave components of heart beating are selected. Strength of wave components of heart beating is determined as general, day and night ones. Generalized factor W is calculated by original relation. Value of W is used for diagnosing absence or presence of hormone-active hyper-plastic process of adrenal glands.
EFFECT: screening testing at out-patient conditions.
2 ex, 2 tbl
FIELD: medicine; cardiology.
SUBSTANCE: electrocardiogram of patients suffering from arterial hypertension is subject to twenty-four-hours monitoring. Spectral analysis of variability of heart beating is carried out. Very low frequency, low frequency and high frequency wave components are selected. General, day and night strength of wave components of heart beating is determined. Any factor is estimated according to the data taken from the spreadsheet. Generalized factor Z is calculated by original mathematical relation. Value of Z is used for judging on level of influence of hormones of adrenal gland onto pace-maker activity of sinus node.
EFFECT: comfort at usage; higher efficiency at non-invasive application.
2 ex, 2 tbl
FIELD: medicine; functional medicine.
SUBSTANCE: method in based upon remote irradiation of human body with set of super wide-band electromagnet pulses with duration of 0,2-1,0 ns, repetition rate of 0,05-30,0 MHZ and average density of flow of energy at irradiated part of human body being equal or less than 0,2 mcW/cm2. Modulation component of pulse repetition rate is selected from received reflected signal which pulse repetition rate is determined by heart activity, which is used for forming heart beat rate signal. The latter is used additionally for estimating index of stress which value of index of stress is included into transmitted communication message of mobile phone.
EFFECT: prolonged monitoring of functional condition of human.
3 cl, 2 dwg
FIELD: medicine, cardiology.
SUBSTANCE: one should register a rhythmocardiogram, detect spectral values for variability of cardiac rhythm, calculate the value of autonomic index, calculate the value of autonomic tonicity by the following formula: AI/lnTp m sq. sec., where AI - autonomic index, lnTp - total power for the spectrum of variability of cardiac rhythm. At values above 3.1 one should diagnose severe flow of autonomic dystonia syndrome, at values being 3.1-2.2 - moderate flow of the mentioned disease, at values ranged 2.1-1.5 - light flow. The method enables to predict the development of hemodynamic disorders.
EFFECT: higher efficiency and accuracy of diagnostics.
FIELD: medicine; cardiology.
SUBSTANCE: device for processing intervals of electrocardiogram has plate with Q-T (J-T) and R-R scales applied onto the plate. Plate is additionally provided with legs, rod and scale pointer at the end, arrows, and catches disposed at ends of Q-T (J-T) scale, Q-Tc (J-Tc) correlated values curves and Q-Tc (J-Tc) scale related to them. Rod is divided by axis to parts to relate as 1:5 in such a way that shorter part of rod has to be movable leg and longer part has to be the pointer of Q-T (J-T) scale. Pointer takes "0" position of Q-T (J-) scale to rest against left catch when legs close up. Motionless arrow is disposed onto longer part of rod under pointer of Q-T and/or J-T scale at level of "0" position of R-R scale. Slider with lock is mounted onto pointer to move along pointer. Slider is provided with two arrows. Formulas for building curves of Q-Tc (J-Tc) corrected values are given.
EFFECT: higher speed and comfort at processing of electrocardiograms.
3 cl, 8 dwg, 1 tbl
FIELD: medicine, electrocardiography.
SUBSTANCE: the present innovation deals with measuring parameters of electrocardiosignal (ECS) ST-segment and their analysis to detect deviations against the norm. At every step of quantization one should form the readings of first-order differences and modules of first-order differences. One should memorize N of readings for the modules of first-order differences coming after ECS readings that correspond to the onset of cardiocycle. Then it is necessary to sum up memorized values of modules and at every step of quantization one should compare the obtained current sum value with previous one. It is necessary to memorize the greater of them and according to maximal value one should form threshold level to compare current value of modules sum. Time moments when sum value is at first greater and then lower against threshold level one should consider to be, correspondingly the onset and the end of ST-segment. Time segment between the onset and the end of ST-segment should be considered as duration of ECS ST-signal. Device to isolate ECS ST-signal on-line contains a block for forming ECS, a block for primary ECS processing, a quantization block, a block for isolating the point of cardiocycle onset and measurement of its duration, a block to form first-order differences, a block to form modules of first-order differences, a block to memorize readings for the modules of first-order differences, a block to detect the number of summarized readings for the modules of first-order differences, a summarizing block, a block to form a threshold level, a block for comparison and a key device. The innovation enables to isolate ST-segment more reliably for wider class of electrocardiograms at different modifications of QRS-complex form.
EFFECT: higher efficiency.
2 cl, 12 dwg