Derivatives of indole, having antiviral activity
The invention relates to new indole derivative of the formula I

Claims
1. Derivatives of indole of the formula
Same patents:
The invention relates to a group of new compounds - heterocyclic derivatives of glycyl-beta-alanine General formula I
< / BR>or pharmaceutically acceptable salt of this compound, where
< / BR>is a 5-8-membered monocyclic heterocyclic, optionally unsaturated ring containing from 1 to 4 heteroatoms selected from the group comprising N and S, and1selected from the group comprising SN, SN2, N, NH, O and S, provided that
< / BR>is not pyrrolidinium when V represents NH;
A represents a group of the formula
< / BR>where Y1selected from the group comprising N-R2and R2means hydrogen; R2means hydrogen, R7when not with R2and R8mean hydrogen, alkyl, substituted alkoxy group, or R2together with R7form a 4 to 12-membered ring containing 2 nitrogen atom a heterocycle, optionally substituted by one or more substituents selected from the group comprising hydroxy, C1-C10< / BR>where R2together with R7form a 5-8-membered ring containing two nitrogen atom a heterocycle, R5means hydrogen, R8means alkyl, optionally substituted by alkoxygroup; or A signifies a group
< / BR>where R2together with R7form a 5-8-membered ring containing 2 nitrogen atom a heterocycle, optionally substituted hydroxy-group; R8- alkyl, substituted alkoxygroup; V means-N(R6)-; R6is hydrogen; Y and Z denote hydrogen, t = 0, n and R = 1, 2; R means X-R3where X is-O-; R3is hydrogen, alkyl; R1selected from the group including aryl, alkyl, optionally substituted one or more times by halogen, alkyl, HE; monocyclic heterocycle; haloalkyl; R11means hydrogen, or a pharmaceutically acceptable salt of the compounds; pharmaceutical compositions having properties antagonist
V
3-integrin, as well as to a method of treating diseases mediated
V
3-integrin in a mammal



A represents a group of the formula






The invention relates to new chemical compounds derived from anthra[2,1-d]isothiazol-3,6,11-trione General formula I, where a is the lowest alkylene, R1and R2(independent) - lower alkyl, or R1and R2together with the nitrogen atom form a six-membered saturated, a heterocycle, which may optionally contain a heteroatom such as oxygen atom, and their pharmaceutically acceptable salts
The invention relates to new epothilone formula 1, where R=CH3N
The invention relates to a derivative benzofurazan or benzo-2,1,3-thiadiazole of the formula I, in which R1represents oxygen or sulfur, R2and R3independently selected from the group consisting of-CR=, M is =CR4- where R4independently represents R, R8is hydrogen, R5selected from the group consisting of-CR=CR1-, -CR=CX-, -(СRR1)n-, R7selected from the group consisting of -(CRR1)n-, -C(O)-, -CRX-, -CXX1-, R6selected from the group consisting of -(CRR1)m-, -C(O)-, -CRX -, -CXX1-, -S - and-O-
The invention relates to a series peptidergic heterocyclic compounds, intermediates used in their receiving and containing pharmaceutical compositions
The invention relates to new imidazole derivative of General formula (1), where n1is an integer from 1 to 3, a represents hydrogen, linear or branched C1-C10-alkyl, which may be optionally substituted C3-C7-cycloalkyl or lower alkoxy, or a radical selected from the group shown in the formula of the invention, Y represents a radical selected from the group described in the claims, or to his new pharmaceutically acceptable salts
The invention relates to new heterocyclic compounds with valuable biological properties, in particular derived dioxide benzothiazine, the pharmaceutical compositions based on them having inhibitory receptor endothelin activity, and to a method of inhibiting endothelin receptor
5-hydroxypyrazol-4-ylcarbamate derivatives of saccharin with herbicide action and herbicide tool // 2159244
The invention relates to new 5-hydroxypyrazol-4-incorporatedin saccharin derivative of formula I
< / BR>in which the substituents have the following meaning: L, M means hydrogen, C1-C4alkyl, chlorine, Z denotes hydrogen, C1-C4alkyl, C3-C8alkenyl, C3-C5quinil, phenyl, Q means the radical CO-J; J means connected to position 4 of the benzene ring 5-hydroxypyrazoles ring of formula II
< / BR>in which R1means C1-C4alkyl, and R2means hydrogen or methyl, and is usually used in agriculture salts of compounds (I)


The invention relates to a new derived benzoxazole General formula (1) or salts thereof, R1represents a chlorine atom, R2is hydrogen, R3represents a methyl group
-acetylthio)-1,3,5-triazine as an antioxidant" target="_blank">
The invention relates to the field of organic chemistry and oil industry, specifically to the new derived contrasena - 2-methoxy-4-morpholin-6-(
-acetylthio)-1,3,5-triazine (OATT), which is active additive, inhibiting the oxidation of vegetable oils (antioxidant)

Piperazine derivatives // 2197488
The invention relates to a method for producing derivatives of imidazole of formula A, where R1represents a substituted heterocycle, R4is phenyl, optionally substituted, R2represents the алкилN3, -(CR10R20)nOR9further as stated in the description
The invention relates to billnum compounds or substituted pyridinium formula (I), where X denotes N or CR8where R8denotes hydrogen, halogen, phenyl, alkyl, alkoxy, alkoxycarbonyl, carboxy, formyl or-NR4R5where R4and R5denote hydrogen, alkyl, alkenyl, cycloalkyl, phenyl, naphthyl; R1aand R1Brepresent trifluoromethyl, alkyl, alkenyl, quinil, cycloalkyl, alkanoyl; R2denotes alkyl, alkenyl, quinil, cycloalkyl; R3denotes hydroxy, TRIFLUOROACETYL, alkanoyl, alkenyl; AG denotes an aromatic or heteroaromatic ring, for example phenyl, naphthyl, pyridyl, furanyl, thiophenyl
The invention relates to a method for 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl] -4H-carbazole-4-she of the formula (I)