Method for the treatment and prevention of diseases of vertebrate animals, is caused by mites and botflies

 

(57) Abstract:

The invention relates to the field of veterinary medicine. The composition contains S-fenvalerate as activitiesthese substance and solvent, glycerin, dimethyl sulfoxide, isopropyl alcohol and polyethylene glycol. The method of treatment allows for single and repeated treatment with an interval of 20-25 days, and also during early chemotherapy hypodermatidae cattle. The method is effective for the treatment and prevention of disease caused by mites and botflies. 2 C.p. f-crystals.

The invention relates to the field of veterinary Parasitology.

There is a method of treatment of vertebrate animals from ticks by drug-based desulfonylation, possibly in a mixture with parasiticidal agents, either oral or dermal dose from 1 to 50 mg/kg (RU 2133091, 1999).

Also known is a method of treatment of animals by the introduction of a drug is highly active against ticks, representing a mixture of fenvalerate and azinphos-bromide in a ratio of 1:1 (EN 2145183, No. 4, 9).

However, the known drugs can have adverse side effects.

The closest in technical essence and the achieved re ogic parasites by applying on the hair of limbs and abdomen animals pasty preparation containing 3.5 wt.% fenvalerate and 10 auxiliary non-toxic ingredients (EN 210 2070, 1998).

Known drug has a protective effect for 168 hours at 100% mortality rate.

The present invention is to increase the protective action of the drug in 100% death of the insects while reducing the concentration of active ingredient in the drug.

The problem is solved by the described method of treatment and prevention of diseases of vertebrate animals, caused by the flare and botflies by applying onto the hair along the spine of animals insecticidal composition containing, in wt.%:

S-fenvalerate - 1 - 3

Glycerol - 3 - 10

Dimethyl sulfoxide - 3 - 15

Isopropyl alcohol is 3 - 12

The glycol - Rest

It is possible to conduct treatment against ticks dose of 30 g/ 100 kg of body weight once or repeatedly with an interval of 20-25 days.

Besides, it is fashionable to use composition during early therapy hypodermatidae cattle once the rate of 15 ml per animal.

It was cooked three part Insulated - 15

Isopropyl alcohol - 5

The glycol - 74

Part 2, wt.%:

S-fenvalerate - 3

Glycerol - 3

Dimethyl sulfoxide - 3

Isopropyl alcohol - 12

The glycol - 79

Part 3, wt.%:

S-fenvalerate - 2

Glycerin - 10

Dimethylformamide - 10

Isopropyl alcohol - 12

The glycol - 66

Compounds 1 and 2 were tested on cows infected ticks.

Part 3 is tested against horseflies during early chemotherapy hypodermatidae cattle.

Below are examples of the treatment of animals of a particular composition.

Methodology for conducting experiments for the destruction of ticks in cattle was pouring animals along the vertebral column at the rate of 30 ml per 100 kg of body weight.

Experience 1.

We chose the four bull weight of 605 kg, infected ixodid ticks.

The first 1 calf was treated with composition 1.

The second 2 calf was treated with composition 2.

The third 3 calf was treated with composition 3.

Fourth 4 goby did not process control.

The first 1 ticks died after 96 hours (full exemption).

The second 2 ticks died ESI were present as at the beginning of the experience.

The residual effect of the drug ranged from 19 to 23 days.

Experience 2.

Picked up 35 heifers with an average weight 31010.

The number of ticks varied from 1 to 5 copies on the head.

Were treated at a dose of 30 ml per 100 kg of body weight composition 2.

Animals were divided into 2 groups of 20 goals - group 1 and 15 goals - group 2.

Group 1 in 20 goals processed in the same manner as in experiment 1.

Group 2 in the amount of 15 goals did not process anything - control group.

In group 1 after 24 hours after treatment died 95.6% of ticks within 48 hours of the ticks were not found.

The first ticks appeared on 19-20 days after processing.

In the second group, the number of ticks remained stable and ranged in animals from 1 to 7 instances.

When re-processing all of the mites were killed during the first days and appeared on 21 - 22 days after treatment.

Experience 3.

Evaluated the effectiveness of the proposed composition during early chemotherapy hypodermatidae cattle (larvae subcutaneous gadfly).

The tool used in the amount of 15 ml per animal drawing along pozvonochnyh animals. The control used 15 goals infested animals that have not been processed. Accounting efficacy was performed 8 months after treatment.

The treated animals during examination gadfly larvae were not found.

Control animals found - 51 larva.

Thus, it is possible to conclude that the high efficiency of the claimed method, which allows for multiple processing of cattle.

1. Method for the treatment and prevention of diseases of vertebrate animals, is caused by mites and botflies, including outside processing hairline animal insecticidal composition containing as an active connection fenvalerate, characterized in that the treatment is carried out by applying along the spine of the animal composition containing, by weight. %:

S - fenvalerate - 1-3

Glycerin - 3-10

Dimethyl sulfoxide - 3-15

Isopropyl alcohol - 3-12

The glycol - Rest

2. The method according to p. 1, characterized in that against ticks, the treatment is carried out once or repeatedly with an interval of 20-25 days a dose of 30 g / 100 kg of body weight of the animal.

3. The method according to p. 1, characterized in that the processing for early hamiota

 

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