A method for preventing esophagostomy of young cattle

 

(57) Abstract:

The invention relates to veterinary helminthology. The method includes intramuscular administration of levamisole at a dose of 2 mg/kg three times with an interval of 10 days prior to pasture cattle on pasture. The way you prevent infection esophagostomy during the grazing period. The effectiveness of the method is 80%. table 1.

The invention relates to veterinary helminthology, in particular to methods of prevention esophagostomy cattle.

There is a method of treatment of strangulation cattle by applying a broad-spectrum anthelmintic action of levamisole dose of 7.5 mg/kg with the introduction of its inward and subcutaneous /Kuzmin A. A. Anthelmintic in veterinary medicine. - M.: The Aquarium, 2000.-S. 63-66/.

The disadvantage of this method is the monthly use of the drug in large therapeutic doses for the recovery of animals from strangulation, because the development cycle of the parasite in the host organism in average ranges from 1 to 1.5 months, so in the pasture period required 3-4 deworming. This involves additional cost and is economically not profitable. In addition to t is. ereki the deaths of animals.

The closest way to the same destination to the claimed invention on the totality of symptoms is the way chemoprophylaxis esophagostomy cattle by feeding deworming drugs fenotiazina mixed with feed or grain grinding once in 3 days during the grazing period (2-3 grams of the drug on the animal). Petrukhin, M. A. therapeutic Efficacy of chemical and preventive degelmintizatsii cattle phenothiazines against esophagostomy //Diseases of farm animals and bees zones of the Far East and countermeasures, " Proc. Dalissime. - Omsk, 1978. -S. 115-117.

The disadvantage of this method is the high cost of the desired feed or grain grinding, a trough (trough), for the period of prevention need large quantity fenotiazina, moreover, with a slight overdose affects the nervous system, kidneys, liver of animals. It is known that a significant portion of fenotiazina excreted in urine, bile and milk. The oxidation products fenotiazina stained urine and milk in intense red color. In calves receiving the drug and those on the sun, develop, kerato is esophagostomy. Extendedrequest this method is 40%.

The essence of the invention lies in the fact that to increase the effectiveness of prevention esophagostomy of young cattle, avoid side effects, cheaper way as deworming prevention funds are used levamisole dose of 2 mg/kg (DW) three times with an interval of 10 days, no later than 10-15 days to pasture animals on pasture.

The proposed method for the prevention of esophagostomy allows you to increase extendedrequest up to 80%, eliminate side effects, cheaper way.

The present invention is as follows. The young cattle born in the late autumn, winter and spring, so not Vipassana on pasture and not infected with esophagostomy, before his pasture to pasture administered levamisole dose of 2 mg/kg (DW) intramuscularly, three times with an interval of 10 days, no later than 10-15 days to pasture cattle on pasture. This method provides 80% protection of animals from esophagostomy.

In examples 1-3 and 5-7 uninfected esophagostomy Guinea young cattle intramuscularly injected levamisole and 20 ntronium animals 4-th and 8-th groups levamisole did not apply, they were infected simultaneously with experimental (200 larvae each) 3 days in a row.

Accounting prophylactic efficacy of levamisole were erosophia faeces from experimental and control animals experience before and 90 days after its application. Prophylactic efficacy of levamisole in the experimental groups was determined at the end of the experiment the number of infected animals (extendedrequest - EE%) and the number found in their larvae (intensifications - IE%) in comparison with the number of infected animals and the number found in their larvae in the control groups.

Example 1. In the experience chose not infected with esophagostomy of girls foerste 4 months in the amount of five heads, which was administered levamisole dose of 2 mg/kg (DW), intramuscularly three times with an interval of 10 days. After 90 days in the experimental group was infected animal, he found 12 larvae. In the control group were infected with 5 animals, they found 180 larvae.

Installed 80% prophylactic efficacy of the proposed method of prevention. Intensifications - 95,4%.

Example 2. Animals of the 2nd group has applied levamisole dose of 2.5 mg/kg, three times with an interval of 10 days. Che is July 80%. Intensifications (IE) - 85%.

Example 3. Animals of the 3rd group were injected levamisole dose of 3 mg/kg, three times with an interval of 10 days. The research showed that after 90 days, two infected animals, they found 40 larvae. The efficiency reached: uh - 60%, IE - 77,8%.

Example 4. Control was a group of animals (5 animals), which levamisole did not apply. After 90 days were mostly infested all 5 animals, they found 180 larvae. The control total for the first three experimental groups.

Example 5. The young 5-th group levamisole was applied intramuscularly in a dose of 2 mg/kg twice with an interval of 20 days. After 90 days in this group was infected animal, they found 28 larvae. Extendedrequest (EE) method was 80%, intensifications (IE) - 83,3%.

Example 6. Animals of the 6th group levamisole applied at a dose of 2.5 mg/kg twice with an interval of 20 days. In this group, one animal was found 35 larvae. Therefore, EE has reached 80%, IE - 79.7 per cent.

Example 7. The young 7-th group, the drug was administered at a dose of 3 mg/kg twice with an interval of 20 days. 90 days 2 infected animals, they found 47 larvae. The extense and intensifications respectively reached 60,0 and 73.3%.

Note the SCP in examples 5, 6 and 7. After 90 days in this group were mostly infested all 5 animals, they found 172 larvae.

Thus, the most effective way to prevent esophagostomy of young cattle is the use of levamisole intramuscularly at a dose of 2 mg/kg three times with an interval of 10 days prior to pasture animals on pasture.

Intramuscular injection provides rapid absorption and as a consequence leads to a faster response of the body, does not cause complications. Subcutaneous application of levamisole often leads to the formation of edema at the injection site.

Levamisole used in a low dose (2 mg/kg) three times with an interval of 10 days, blocking mass migration of larvae through the body and provides follow-up immunity of the body to invasion. The protective properties are expressed in reduced survival rate of larvae in 6-15 times (see table).

The proposed method can prevent infection esophagostomy, provides the resistance of animals to esophagostomy 80%, which is stored during the grazing period. The proposed method does not cause side effects, cost-effective, because the drug need only the th cattle, including the introduction of animals chemotherapeutic drug, characterized in that as the drug is administered intramuscularly levamisole dose of 2 mg/kg three times with 10-day intervals to pasture cattle on pasture.

 

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