The method of obtaining politicologie oil "kyzylmai"

 

(57) Abstract:

The invention relates to the pharmaceutical industry. Collect herbs St. John's wort, thyme, nettle, rosehips and licorice root, extraction, filtering and mixing of extracts. And after collecting conduct wilting raw materials for at least 24 h Extraction are consistently small vegetable, beeswax and liquefied carbon dioxide, then added to the mixture of sea buckthorn oil. Filtering is carried out in two stages, using filters rough and deep cleaning. The invention allows to expand the range of tools and to increase its shelf life.

The invention relates to pharmaceutical industry and can be used in the manufacture of medicinal products from vegetable raw materials.

A method of obtaining sea-buckthorn oil by extraction of the berries of sea buckthorn oil at multistage process with the additional use of organic solvents (tsybikova D. I. and other Chemical and pharmacological characterization of fat-soluble complex of sea buckthorn. The science. Siberian branch. 1991).

The disadvantage of this method is that in the as fraction.

A method of obtaining rosehip oil from the seeds and fruits of wild rose by extraction using organic solvents (satuk L. N. Development of preventive foods rich in beta-carotene. Carotenoids in Oncology. The Symposium materials. M., 1992).

The disadvantage of this method is that used dry, dried poroshkovanie raw material that increases the viscosity of the extract and reduces its output, thus reducing the amount of extractives.

A method of obtaining oil extract, including extraction of the crushed plant material, filtering and mixing of extracts (patent RU 2078577, 1997).

The disadvantage of this method is incomplete extraction of biologically active substances.

Closest to the claimed solution is a method for politicologie oil "kyzylmai", including extraction of plant raw materials containing various vegetative organs nettle, licorice, rose hips, lemon balm, thyme, St. John's wort, filtering the obtained extracts and their mixing (PREV. patent of the Republic of Kazakhstan 10174, 2001).

The disadvantage of this method is t is holding extractives, because vegetable oil is used as the sole extractant has a low absorption rate and can not dissolve a significant amount of extractives. In addition, obtained by the above method extracts subjected to the fermentation process due to the lack of stabilizing components, which increases the risk of microbial contamination, reducing the durability of the product and its shelf life.

The task of the claimed invention is to expand the range of therapeutic action politicologie oil by increasing complex extractives, store them in a natural form and layout, as well as increasing the shelf life of the drug.

The method of obtaining politicologie oil enables the collection of plant materials in the period of maximum accumulation of biologically active substances containing the herb St. John's wort, lemon balm, thyme, nettle, wild rose hips, licorice root, extraction, filtering and mixing, and after collecting conduct wilting raw materials for at least 24 h, the extraction are consistent with vegetable oil, beeswax and liquefied carbon dioxide, then added to the mixture of sea buckthorn oil and filter you spend St. John's wort, nettle leaves, rosehips, of sea-buckthorn berries, licorice root, herb, lemon balm and thyme are volatile, essential oils, resins, balsams, fat-soluble and water-soluble vitamins, organic acids and glucosides polifenoles, triterpenoid and antrahinonovye patterns. Poisonous compounds used in the plant is not contained. In-depth biochemical analysis showed the presence of politicum oil mg%: carotenoids is about 2; flavanoids - 0,5; tocopherol - 14,1; retinol - 0,001; unsaturated fatty acids: oleic - 18,5; linolenic - 0,7; erucic - 1, as well as of trace elements such as MnO, Mg, Co, Si, Ca, Ti, etc. Check for radioactivity showed lack thereof.

Carbon dioxide extraction allows you to fully extract essential oils and herbal antibiotics, thereby increasing the antiseptic politicologie oil.

The use of beeswax helps to further extract from plant raw material resins, balsams, vegetable wax, inhibits the rancidification of fats, increases the stability of the drug extends the range of its pharmacological action and increases shelf life.

As the vegetable oil is some degree of purification.

Using sea buckthorn oil provides a tonic effect politicologie oil and cheapens the process of its manufacture.

High quality, stability and a wide range of pharmacological actions politicologie oil provided by the peculiarities of the method of its production. The above raw materials are collected in terms of the maximum content of bioactive substances, respectively, by types (may to October). Prepared for the extraction of raw materials moved and displayed on the hair grilles for drying for at least 24 hours This operation increases the amount of bioactive substances and reduces the subsequent risk of fermentation of the extract due to the fact that the dried raw materials significantly reduces the amount of moisture.

Feature extraction three groups lipophilic extracting agent (vegetable oil, beeswax and liquefied carbon dioxide) allows you to completely drain the vegetable raw materials and to obtain the maximum number of biologically active substances.

All operations are carried out at moderate regimes, excluding heated above 80oWith increasing pressure above 2 ATM. In order to avoid microbial contamination, filtration Privoxy fine mechanical impurities (>0.65 micron), including microbial and fungal microflora.

The method of obtaining politicologie oil is as follows. Collect raw materials:

St. John's wort herb (top 5-7 cm) - may-June;

the herb lemon balm (top 7-10 cm) - June-July;

herb thyme (top 7-10 cm) - June-July;

the nettle (5-10 cm) - may-June;

rosehips (2-3 cm) - September-October;

licorice root (3-5 cm) - October-November.

The raw materials were podkalyvali gratings within 24 hours

Dried raw material was poured vegetable oil, insisted within 45 days, then extraction was performed with beeswax and liquefied carbon dioxide. The obtained extracts were mixed, added sea buckthorn oil, defended and held the two-stage filter - coarse delay large particles and deep - for a delay of small particles and eliminate microbiological contamination (bacterial filter Company "Sartorius").

Thus, the inventive method of obtaining politicologie oil allows to obtain multi-component extracts of each of the raw materials, without altering the natural structure and activity of therapeutic substances, to enhance their stability, and became to be, and Spektr due to the multicomponent composition top three extractants, with polypetalae oil has anti-inflammatory, wound healing, immune stimulating, anti-allergic and antiseptic effect. This method is economical due to the complete depletion of raw materials during the extraction, which leads to the reduction of its volume when the workpiece and allows you to continuously reduce the cost of the final product. Add ready buckthorn oil simplifies the manufacturing process, improves the quality of the extract and cheapens the final product.

Clinical trials confirm the effectiveness of the use politicologie oil, obtained by the claimed method.

Use politicologie oil in the treatment of dental diseases showed that the expressed therapeutic effect of the drug was 82-87%, while use of traditional methods of treatment this indicator was equal to 61%.

Positive results were registered in pediatric and adult otolaryngology. Data analysis revealed a pronounced positive effect of the drug when subtropically and purulent rhinitis, acute tonsillitis, subtropically pharyngitis.

The efficiency of the frequency of postoperative complications from 15.5-29,9% to 2.8 to 3.5%.

The positive effect from the use of politicologie oils marked and in gastroenterology. Ulcerative defect in the period of exacerbation of the introduction of this drug led to the disappearance of pain after one or two procedures and scarring ulcers 15-18 day.

Polypetalae oil has also found application in surgery and traumatology. The use of the terms epithelialization of the wound surface was truncated on 38-45%. Burn the surface rapidly epithelials, without suppuration, with complete healing in 5-6 days.

Preventive and curative effect politicologie oil identified and radiation therapy. The application of the drug to the sites of breast irradiation in neither case did not develop postradiation epidermis (in control group - patients (100%).

Thus, the inventive method of obtaining politicologie oil allows to obtain a product with a wide pharmacological spectrum of long term storage.

The method of obtaining politicologie oil, including the collection of plant materials in the period of maximum accumulation of biologically active substances containing St. John's wort, the herb lemon balm, thyme, nettle, rosehips and root solodki the t wilting raw materials for at least 24 h, extraction was carried out consistently with vegetable oil, beeswax and liquefied carbon dioxide, then added to the mixture of sea buckthorn oil, and filtering is carried out in two stages, and use filters rough and deep cleaning.

 

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